Year |
Citation |
Score |
2023 |
McGrail DJ, Li Y, Smith RS, Feng B, Dai H, Hu L, Dennehey B, Awasthi S, Mendillo ML, Sood AK, Mills GB, Lin SY, Yi SS, Sahni N. Widespread BRCA1/2-independent homologous recombination defects are caused by alterations in RNA-binding proteins. Cell Reports. Medicine. 101255. PMID 37909041 DOI: 10.1016/j.xcrm.2023.101255 |
0.302 |
|
2023 |
Li MM, Awasthi S, Ghosh S, Bisht D, Coban Akdemir ZH, Sheynkman GM, Sahni N, Yi SS. Gain-of-Function Variomics and Multi-omics Network Biology for Precision Medicine. Methods in Molecular Biology (Clifton, N.J.). 2660: 357-372. PMID 37191809 DOI: 10.1007/978-1-0716-3163-8_24 |
0.332 |
|
2020 |
Li Y, Burgman B, Khatri IS, Pentaparthi SR, Su Z, McGrail DJ, Li Y, Wu E, Eckhardt SG, Sahni N, Yi SS. e-MutPath: computational modeling reveals the functional landscape of genetic mutations rewiring interactome networks. Nucleic Acids Research. PMID 33211847 DOI: 10.1093/nar/gkaa1015 |
0.328 |
|
2020 |
Li Y, Burgman B, McGrail DJ, Sun M, Qi D, Shukla SA, Wu E, Capasso A, Lin SY, Wu CJ, Eckhardt SG, Mills GB, Li B, Sahni N, Yi SS. Integrated Genomic Characterization of the Human Immunome in Cancer. Cancer Research. PMID 32855206 DOI: 10.1158/0008-5472.Can-20-0384 |
0.43 |
|
2020 |
Liu XD, Kong W, Peterson CB, McGrail DJ, Hoang A, Zhang X, Lam T, Pilie PG, Zhu H, Beckermann KE, Haake SM, Isgandrova S, Martinez-Moczygemba M, Sahni N, Tannir NM, et al. PBRM1 loss defines a nonimmunogenic tumor phenotype associated with checkpoint inhibitor resistance in renal carcinoma. Nature Communications. 11: 2135. PMID 32358509 DOI: 10.1038/S41467-020-15959-6 |
0.334 |
|
2020 |
Daniels J, Doukas PG, Escala MEM, Ringbloom KG, Shih DJH, Yang J, Tegtmeyer K, Park J, Thomas JJ, Selli ME, Altunbulakli C, Gowthaman R, Mo SH, Jothishankar B, Pease DR, ... ... Sahni N, et al. Cellular origins and genetic landscape of cutaneous gamma delta T cell lymphomas. Nature Communications. 11: 1806. PMID 32286303 DOI: 10.1038/S41467-020-15572-7 |
0.321 |
|
2020 |
McGrail DJ, Garnett J, Yin J, Dai H, Shih DJH, Lam TNA, Li Y, Sun C, Li Y, Schmandt R, Wu JY, Hu L, Liang Y, Peng G, Jonasch E, ... ... Sahni N, et al. Proteome Instability Is a Therapeutic Vulnerability in Mismatch Repair-Deficient Cancer. Cancer Cell. PMID 32109374 DOI: 10.1016/J.Ccell.2020.01.011 |
0.394 |
|
2020 |
Sahni N, McGrail DJ, Garnett J, Yin J, Dai H, Shih DJH, Peng G, Menter D, Yates MS, Kopetz S, Lu K, Broaddus R, Mills GB, Lin SY. Abstract NG14: Proteome instability is an immunogenic therapeutic vulnerability in mismatch repair deficient cancer Cancer Research. 80. DOI: 10.1158/1538-7445.Am2020-Ng14 |
0.386 |
|
2019 |
Li Y, McGrail DJ, Xu J, Li J, Yi S, Sahni N. Abstract 3390: RNA interactome topology perturbation analysis reveals candidate driver mutations in cancer Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-3390 |
0.556 |
|
2019 |
Sahni N, McGrail D, Li Y, Mills G, Yi S(. Abstract 1646: Beyond BRCA: Discovery of novel drivers of homologous recombination deficiencies in cancer Cancer Research. 79: 1646-1646. DOI: 10.1158/1538-7445.Am2019-1646 |
0.418 |
|
2018 |
Ip CKM, Ng PKS, Jeong KJ, Shao SH, Ju Z, Leonard PG, Hua X, Vellano CP, Woessner R, Sahni N, Scott KL, Mills GB. Neomorphic PDGFRA extracellular domain driver mutations are resistant to PDGFRA targeted therapies. Nature Communications. 9: 4583. PMID 30389923 DOI: 10.1038/S41467-018-06949-W |
0.363 |
|
2018 |
Li Y, McGrail DJ, Xu J, Li J, Liu NN, Sun M, Lin R, Pancsa R, Zhang J, Lee JS, Wang H, Mills GB, Li X, Yi S, Sahni N. MERIT: Systematic analysis and characterization of Mutational Effect on RNA Interactome Topology. Hepatology (Baltimore, Md.). PMID 30153342 DOI: 10.1002/Hep.30242 |
0.617 |
|
2018 |
Lu J, Xu J, Li J, Pan T, Bai J, Wang L, Jin X, Lin X, Zhang Y, Li Y, Sahni N, Li X. FACER: comprehensive molecular and functional characterization of epigenetic chromatin regulators. Nucleic Acids Research. PMID 30102398 DOI: 10.1093/Nar/Gky679 |
0.353 |
|
2018 |
Li Y, McGrail DJ, Xu J, Mills GB, Sahni N, Yi S. Gene Regulatory Network Perturbation by Genetic and Epigenetic Variation. Trends in Biochemical Sciences. PMID 29941230 DOI: 10.1016/J.Tibs.2018.05.002 |
0.574 |
|
2018 |
Li Y, McGrail DJ, Latysheva N, Yi S, Babu MM, Sahni N. Pathway perturbations in signaling networks: Linking genotype to phenotype. Seminars in Cell & Developmental Biology. PMID 29738884 DOI: 10.1016/J.Semcdb.2018.05.001 |
0.614 |
|
2018 |
McGrail DJ, Federico L, Li Y, Dai H, Lu Y, Mills GB, Yi S, Lin SY, Sahni N. Multi-omics analysis reveals neoantigen-independent immune cell infiltration in copy-number driven cancers. Nature Communications. 9: 1317. PMID 29615613 DOI: 10.1038/S41467-018-03730-X |
0.548 |
|
2018 |
Ng PK, Li J, Jeong KJ, Shao S, Chen H, Tsang YH, Sengupta S, Wang Z, Bhavana VH, Tran R, Soewito S, Minussi DC, Moreno D, Kong K, Dogruluk T, ... ... Sahni N, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 33: 450-462.e10. PMID 29533785 DOI: 10.1016/J.Ccell.2018.01.021 |
0.607 |
|
2018 |
Li Y, Li L, Wang Z, Pan T, Sahni N, Jin X, Wang G, Li J, Zheng X, Zhang Y, Xu J, Yi S, Li X. LncMAP: Pan-cancer atlas of long noncoding RNA-mediated transcriptional network perturbations. Nucleic Acids Research. PMID 29325141 DOI: 10.1093/Nar/Gkx1311 |
0.582 |
|
2018 |
Liang H, Ng PK, Li J, Jeong KJ, Lu Y, Yi S, Sahni N, Mills G. Abstract 397: Systematic functional annotation of somatic mutations in cancer Cancer Research. 78: 397-397. DOI: 10.1158/1538-7445.Am2018-397 |
0.611 |
|
2017 |
Li Y, Sahni N, Pancsa R, McGrail DJ, Xu J, Hua X, Coulombe-Huntington J, Ryan M, Tychhon B, Sudhakar D, Hu L, Tyers M, Jiang X, Lin SY, Babu MM, et al. Revealing the Determinants of Widespread Alternative Splicing Perturbation in Cancer. Cell Reports. 21: 798-812. PMID 29045845 DOI: 10.1016/J.Celrep.2017.09.071 |
0.62 |
|
2017 |
Yi S, Liu NN, Hu L, Wang H, Sahni N. Base-resolution stratification of cancer mutations using functional variomics. Nature Protocols. 12: 2323-2341. PMID 28981122 DOI: 10.1038/Nprot.2017.086 |
0.597 |
|
2017 |
Yi S, Sahni N. Regulome Networks and Mutational Landscape in Liver Cancer: An Informative Path to Precision Medicine. Hepatology (Baltimore, Md.). PMID 28422313 DOI: 10.1002/Hep.29220 |
0.552 |
|
2017 |
Yi S, Lin S, Li Y, Zhao W, Mills GB, Sahni N. Functional variomics and network perturbation: connecting genotype to phenotype in cancer. Nature Reviews. Genetics. PMID 28344341 DOI: 10.1038/Nrg.2017.8 |
0.63 |
|
2017 |
Karras GI, Yi S, Sahni N, Fischer M, Xie J, Vidal M, D'Andrea AD, Whitesell L, Lindquist S. HSP90 Shapes the Consequences of Human Genetic Variation. Cell. PMID 28215707 DOI: 10.1016/J.Cell.2017.01.023 |
0.556 |
|
2017 |
Chung CY, Khurana V, Yi S, Sahni N, Loh KH, Auluck PK, Baru V, Udeshi ND, Freyzon Y, Carr SA, Hill DE, Vidal M, Ting AY, Lindquist S. In Situ Peroxidase Labeling and Mass-Spectrometry Connects Alpha-Synuclein Directly to Endocytic Trafficking and mRNA Metabolism in Neurons. Cell Systems. PMID 28131823 DOI: 10.1016/J.Cels.2017.01.002 |
0.525 |
|
2017 |
Sahni N, Yi S. Abstract B03: Functional Stratification of Cancer Variants via Network Perturbations Molecular Cancer Therapeutics. 16. DOI: 10.1158/1538-8514.Synthleth-B03 |
0.625 |
|
2017 |
Yi S, Sahni N. Abstract 5556: Widespread protein interactome network rewiring in human cancer Cancer Research. 77: 5556-5556. DOI: 10.1158/1538-7445.Am2017-5556 |
0.629 |
|
2017 |
Sahni N, Yi S. Abstract 5555: Integrative network variomics reveals complex genotype to phenotype relationships in cancer Cancer Research. 77: 5555-5555. DOI: 10.1158/1538-7445.Am2017-5555 |
0.549 |
|
2016 |
Li Y, Sahni N, Yi S. Comparative analysis of protein interactome networks prioritizes candidate genes with cancer signatures. Oncotarget. PMID 27791983 DOI: 10.18632/Oncotarget.12879 |
0.601 |
|
2016 |
Yi S, Chen S, Zhang L, Sahni N. Signal Transduction and Regulation: Insights into Evolution. Biomed Research International. 2016: 8604245. PMID 27525280 DOI: 10.1155/2016/8604245 |
0.542 |
|
2016 |
Lin S, Yin YA, Jiang X, Sahni N, Yi S. Multi-OMICs and Genome Editing Perspectives on Liver Cancer Signaling Networks. Biomed Research International. 2016: 6186281. PMID 27403431 DOI: 10.1155/2016/6186281 |
0.589 |
|
2016 |
Yachie N, Petsalaki E, Mellor JC, Weile J, Jacob Y, Verby M, Ozturk SB, Li S, Cote AG, Mosca R, Knapp JJ, Ko M, Yu A, Gebbia M, Sahni N, et al. Pooled-matrix protein interaction screens using Barcode Fusion Genetics. Molecular Systems Biology. 12: 863. PMID 27107012 DOI: 10.15252/Msb.20156660 |
0.537 |
|
2016 |
Barrera LA, Vedenko A, Kurland JV, Rogers JM, Gisselbrecht SS, Rossin EJ, Woodard J, Mariani L, Kock KH, Inukai S, Siggers T, Shokri L, Gordân R, Sahni N, Cotsapas C, et al. Survey of variation in human transcription factors reveals prevalent DNA binding changes. Science (New York, N.Y.). 351: 1450-4. PMID 27013732 DOI: 10.1126/Science.Aad2257 |
0.518 |
|
2016 |
Sun S, Yang F, Tan G, Costanzo M, Oughtred R, Hirschman J, Theesfeld C, Bansal P, Sahni N, Yi S, Yu A, Tyagi T, Tie C, Hill DE, Vidal M, et al. An extended set of yeast-based functional assays accurately identifies human disease mutations. Genome Research. PMID 26975778 DOI: 10.1101/Gr.192526.115 |
0.562 |
|
2016 |
Yang X, Coulombe-Huntington J, Kang S, Sheynkman GM, Hao T, Richardson A, Sun S, Yang F, Shen YA, Murray RR, Spirohn K, Begg BE, Duran-Frigola M, MacWilliams A, Pevzner SJ, ... ... Sahni N, et al. Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing. Cell. 164: 805-817. PMID 26871637 DOI: 10.1016/J.Cell.2016.01.029 |
0.567 |
|
2015 |
Wang Y, Sahni N, Vidal M. Global Edgetic Rewiring in Cancer Networks. Cell Systems. 1: 251-253. PMID 27136053 DOI: 10.1016/J.Cels.2015.10.006 |
0.389 |
|
2015 |
Fuxman Bass JI, Sahni N, Shrestha S, Garcia-Gonzalez A, Mori A, Bhat N, Yi S, Hill DE, Vidal M, Walhout AJ. Human gene-centered transcription factor networks for enhancers and disease variants. Cell. 161: 661-73. PMID 25910213 DOI: 10.1016/J.Cell.2015.03.003 |
0.607 |
|
2015 |
Sahni N, Yi S, Taipale M, Fuxman Bass JI, Coulombe-Huntington J, Yang F, Peng J, Weile J, Karras GI, Wang Y, Kovács IA, Kamburov A, Krykbaeva I, Lam MH, Tucker G, et al. Widespread macromolecular interaction perturbations in human genetic disorders. Cell. 161: 647-60. PMID 25910212 DOI: 10.1016/J.Cell.2015.04.013 |
0.579 |
|
2015 |
Sharma A, Menche J, Huang CC, Ort T, Zhou X, Kitsak M, Sahni N, Thibault D, Voung L, Guo F, Ghiassian SD, Gulbahce N, Baribaud F, Tocker J, Dobrin R, et al. A disease module in the interactome explains disease heterogeneity, drug response and captures novel pathways and genes in asthma. Human Molecular Genetics. 24: 3005-20. PMID 25586491 DOI: 10.1093/Hmg/Ddv001 |
0.316 |
|
2014 |
Rolland T, TaÅŸan M, Charloteaux B, Pevzner SJ, Zhong Q, Sahni N, Yi S, Lemmens I, Fontanillo C, Mosca R, Kamburov A, Ghiassian SD, Yang X, Ghamsari L, Balcha D, et al. A proteome-scale map of the human interactome network. Cell. 159: 1212-26. PMID 25416956 DOI: 10.1016/J.Cell.2014.10.050 |
0.559 |
|
2014 |
Hill SJ, Rolland T, Adelmant G, Xia X, Owen MS, Dricot A, Zack TI, Sahni N, Jacob Y, Hao T, McKinney KM, Clark AP, Reyon D, Tsai SQ, Joung JK, et al. Systematic screening reveals a role for BRCA1 in the response to transcription-associated DNA damage. Genes & Development. 28: 1957-75. PMID 25184681 DOI: 10.1101/Gad.241620.114 |
0.354 |
|
2014 |
Dittmer TA, Sahni N, Kubben N, Hill DE, Vidal M, Burgess RC, Roukos V, Misteli T. Systematic identification of pathological lamin A interactors. Molecular Biology of the Cell. 25: 1493-510. PMID 24623722 DOI: 10.1091/Mbc.E14-02-0733 |
0.403 |
|
2013 |
Sahni N, Yi S, Zhong Q, Jailkhani N, Charloteaux B, Cusick ME, Vidal M. Edgotype: a fundamental link between genotype and phenotype. Current Opinion in Genetics & Development. 23: 649-57. PMID 24287335 DOI: 10.1016/J.Gde.2013.11.002 |
0.593 |
|
2012 |
Srikantha T, Daniels KJ, Pujol C, Sahni N, Yi S, Soll DR. Nonsex genes in the mating type locus of Candida albicans play roles in a/α biofilm formation, including impermeability and fluconazole resistance. Plos Pathogens. 8: e1002476. PMID 22253594 DOI: 10.1371/Journal.Ppat.1002476 |
0.662 |
|
2011 |
Yi S, Sahni N, Daniels KJ, Lu KL, Srikantha T, Huang G, Garnaas AM, Soll DR. Alternative mating type configurations (a/α versus a/a or α/α) of Candida albicans result in alternative biofilms regulated by different pathways. Plos Biology. 9: e1001117. PMID 21829325 DOI: 10.1371/Journal.Pbio.1001117 |
0.654 |
|
2011 |
Yi S, Sahni N, Daniels KJ, Lu KL, Huang G, Srikantha T, Soll DR. Self-induction of a/a or alpha/alpha biofilms in Candida albicans is a pheromone-based paracrine system requiring switching. Eukaryotic Cell. 10: 753-60. PMID 21498642 DOI: 10.1128/Ec.05055-11 |
0.661 |
|
2011 |
Yi S, Sahni N, Daniels KJ, Lu KL, Huang G, Garnaas AM, Pujol C, Srikantha T, Soll DR. Utilization of the mating scaffold protein in the evolution of a new signal transduction pathway for biofilm development. Mbio. 2: e00237-10. PMID 21221248 DOI: 10.1128/Mbio.00237-10 |
0.68 |
|
2010 |
Sahni N, Yi S, Daniels KJ, Huang G, Srikantha T, Soll DR. Tec1 mediates the pheromone response of the white phenotype of Candida albicans: insights into the evolution of new signal transduction pathways. Plos Biology. 8: e1000363. PMID 20454615 DOI: 10.1371/Journal.Pbio.1000363 |
0.657 |
|
2010 |
Huang G, Yi S, Sahni N, Daniels KJ, Srikantha T, Soll DR. N-acetylglucosamine induces white to opaque switching, a mating prerequisite in Candida albicans. Plos Pathogens. 6: e1000806. PMID 20300604 DOI: 10.1371/Journal.Ppat.1000806 |
0.655 |
|
2010 |
Huang G, Yi S, Sahni N, Daniels KJ, Srikantha T, Soll DR. Correction: N-Acetylglucosamine Induces White to Opaque Switching, a Mating Prerequisite in Candida albicans Plos Pathogens. 6. DOI: 10.1371/Annotation/Ed4D1473-Cf80-4E85-Ad9D-7A390Be260F6 |
0.583 |
|
2009 |
Sahni N, Yi S, Daniels KJ, Srikantha T, Pujol C, Soll DR. Genes selectively up-regulated by pheromone in white cells are involved in biofilm formation in Candida albicans. Plos Pathogens. 5: e1000601. PMID 19798425 DOI: 10.1371/Journal.Ppat.1000601 |
0.67 |
|
2009 |
Huang G, Srikantha T, Sahni N, Yi S, Soll DR. CO(2) regulates white-to-opaque switching in Candida albicans. Current Biology : Cb. 19: 330-4. PMID 19200725 DOI: 10.1016/J.Cub.2009.01.018 |
0.655 |
|
2009 |
Yi S, Sahni N, Pujol C, Daniels KJ, Srikantha T, Ma N, Soll DR. A Candida albicans-specific region of the alpha-pheromone receptor plays a selective role in the white cell pheromone response. Molecular Microbiology. 71: 925-47. PMID 19170873 DOI: 10.1111/J.1365-2958.2008.06575.X |
0.654 |
|
2009 |
Sahni N, Yi S, Pujol C, Soll DR. The white cell response to pheromone is a general characteristic of Candida albicans strains. Eukaryotic Cell. 8: 251-6. PMID 19074600 DOI: 10.1128/Ec.00320-08 |
0.631 |
|
2008 |
Srikantha T, Daniels KJ, Wu W, Lockhart SR, Yi S, Sahni N, Ma N, Soll DR. Dark brown is the more virulent of the switch phenotypes of Candida glabrata. Microbiology (Reading, England). 154: 3309-18. PMID 18957584 DOI: 10.1099/Mic.0.2008/020578-0 |
0.635 |
|
2008 |
Yi S, Sahni N, Daniels KJ, Pujol C, Srikantha T, Soll DR. The same receptor, G protein, and mitogen-activated protein kinase pathway activate different downstream regulators in the alternative white and opaque pheromone responses of Candida albicans. Molecular Biology of the Cell. 19: 957-70. PMID 18162580 DOI: 10.1091/Mbc.E07-07-0688 |
0.674 |
|
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