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Kenneth E. Prehoda - Publications

Affiliations: 
Chemistry and Biochemistry University of Oregon, Eugene, OR, United States 
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69 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Vargas E, Penkert RR, Prehoda KE. A PDZ-kinase allosteric relay mediates Par complex regulator exchange. The Journal of Biological Chemistry. 301: 108097. PMID 39706275 DOI: 10.1016/j.jbc.2024.108097  0.371
2024 LaFoya B, Welch SE, Prehoda KE. Lgl resets Par complex membrane loading at mitotic exit to enable asymmetric neural stem cell division. Biorxiv : the Preprint Server For Biology. PMID 39677723 DOI: 10.1101/2024.09.29.615680  0.314
2024 Vargas E, Penkert RR, Prehoda KE. A PDZ-kinase allosteric relay mediates Par complex regulator exchange. Biorxiv : the Preprint Server For Biology. PMID 39464081 DOI: 10.1101/2024.10.18.619144  0.377
2023 Jones KA, Drummond ML, Penkert RR, Prehoda KE. Cooperative regulation of C1-domain membrane recruitment polarizes atypical protein kinase C. The Journal of Cell Biology. 222. PMID 37589718 DOI: 10.1083/jcb.202112143  0.791
2023 LaFoya B, Prehoda KE. Consumption of a polarized membrane reservoir drives asymmetric membrane expansion during the unequal divisions of neural stem cells. Developmental Cell. 58: 993-1003.e3. PMID 37116487 DOI: 10.1016/j.devcel.2023.04.006  0.343
2022 Vargas E, Prehoda KE. Negative cooperativity underlies dynamic assembly of the Par complex regulators Cdc42 and Par-3. The Journal of Biological Chemistry. 299: 102749. PMID 36436559 DOI: 10.1016/j.jbc.2022.102749  0.484
2022 Penkert RR, Vargas E, Prehoda KE. Energetic determinants of animal cell polarity regulator Par-3 interaction with the Par complex. The Journal of Biological Chemistry. 102223. PMID 35787373 DOI: 10.1016/j.jbc.2022.102223  0.504
2021 Oon CH, Prehoda KE. Phases of cortical actomyosin dynamics coupled to the neuroblast polarity cycle. Elife. 10. PMID 34779402 DOI: 10.7554/eLife.66574  0.385
2021 LaFoya B, Prehoda KE. Actin-dependent membrane polarization reveals the mechanical nature of the neuroblast polarity cycle. Cell Reports. 35: 109146. PMID 34010656 DOI: 10.1016/j.celrep.2021.109146  0.39
2021 Dishman AF, Tyler RC, Fox JC, Kleist AB, Prehoda KE, Babu MM, Peterson FC, Volkman BF. Evolution of fold switching in a metamorphic protein. Science (New York, N.Y.). 371: 86-90. PMID 33384377 DOI: 10.1126/science.abd8700  0.338
2020 Holly RW, Jones K, Prehoda KE. A Conserved PDZ-Binding Motif in aPKC Interacts with Par-3 and Mediates Cortical Polarity. Current Biology : Cb. PMID 32084408 DOI: 10.1016/J.Cub.2019.12.055  0.811
2019 Holly RW, Prehoda KE. Phosphorylation of Par-3 by Atypical Protein Kinase C and Competition between Its Substrates. Developmental Cell. 49: 678-679. PMID 31163172 DOI: 10.1016/J.Devcel.2019.05.002  0.407
2019 Oon CH, Prehoda KE. Asymmetric recruitment and actin-dependent cortical flows drive the neuroblast polarity cycle. Elife. 8. PMID 31066675 DOI: 10.7554/Elife.45815  0.493
2019 Oon CH, Prehoda KE. Author response: Asymmetric recruitment and actin-dependent cortical flows drive the neuroblast polarity cycle Elife. DOI: 10.7554/Elife.45815.025  0.43
2017 Golub O, Wee B, Newman RA, Paterson NM, Prehoda KE. Activation of Discs large by aPKC aligns the mitotic spindle to the polarity axis during asymmetric cell division. Elife. 6. PMID 29185419 DOI: 10.7554/Elife.32137  0.584
2017 Golub O, Wee B, Newman RA, Paterson NM, Prehoda KE. Author response: Activation of Discs large by aPKC aligns the mitotic spindle to the polarity axis during asymmetric cell division Elife. DOI: 10.7554/Elife.32137.018  0.457
2016 Whitney DS, Volkman BF, Prehoda KE. Evolution of a protein interaction domain family by tuning conformational flexibility. Journal of the American Chemical Society. PMID 27502157 DOI: 10.1021/Jacs.6B05954  0.512
2016 Whitney DS, Peterson FC, Kittell AW, Egner JM, Prehoda KE, Volkman BF. Correction to Binding of Crumbs to the Par-6 CRIB-PDZ Module Is Regulated by Cdc42. Biochemistry. PMID 27012924 DOI: 10.1021/Acs.Biochem.6B00254  0.442
2016 Drummond ML, Prehoda KE. Molecular control of atypical protein kinase C: Tipping the balance between self-renewal and differentiation. Journal of Molecular Biology. PMID 26992354 DOI: 10.1016/J.Jmb.2016.03.003  0.45
2016 Whitney DS, Peterson FC, Kittell AW, Egner JM, Prehoda KE, Volkman BF. Crumbs binding to the Par-6 CRIB-PDZ module is regulated by Cdc42. Biochemistry. PMID 26894406 DOI: 10.1021/Acs.Biochem.5B01342  0.53
2016 Anderson DP, Whitney DS, Hanson-Smith V, Woznica A, Campodonico-Burnett W, Volkman BF, King N, Thornton JW, Prehoda KE. Correction: Evolution of an ancient protein function involved in organized multicellularity in animals. Elife. 5. PMID 26790885 DOI: 10.7554/Elife.14311  0.603
2016 Anderson DP, Whitney DS, Hanson-Smith V, Woznica A, Campodonico-Burnett W, Volkman BF, King N, Prehoda KE, Thornton JW. Evolution of an ancient protein function involved in organized multicellularity in animals. Elife. 5. PMID 26740169 DOI: 10.7554/Elife.10147  0.687
2015 Bailey MJ, Prehoda KE. Establishment of Par-Polarized Cortical Domains via Phosphoregulated Membrane Motifs. Developmental Cell. 35: 199-210. PMID 26481050 DOI: 10.1016/J.Devcel.2015.09.016  0.587
2014 Graybill C, Prehoda KE. Ordered multisite phosphorylation of lethal giant larvae by atypical protein kinase C. Biochemistry. 53: 4931-7. PMID 25000553 DOI: 10.1021/Bi500748W  0.471
2013 Lu MS, Prehoda KE. A NudE/14-3-3 pathway coordinates dynein and the kinesin Khc73 to position the mitotic spindle. Developmental Cell. 26: 369-80. PMID 23987511 DOI: 10.1016/J.Devcel.2013.07.021  0.506
2013 Johnston CA, Manning L, Lu MS, Golub O, Doe CQ, Prehoda KE. Formin-mediated actin polymerization cooperates with Mushroom body defect (Mud)-Dynein during Frizzled-Dishevelled spindle orientation. Journal of Cell Science. 126: 4436-44. PMID 23868974 DOI: 10.1242/Dev.104356  0.656
2012 Prehoda KE. Microtubules in distress release arrest. Developmental Cell. 23: 233-4. PMID 22898771 DOI: 10.1016/J.Devcel.2012.07.005  0.375
2012 Lu MS, Mauser JF, Prehoda KE. Ultrasensitive synthetic protein regulatory networks using mixed decoys. Acs Synthetic Biology. 1: 65-72. PMID 22639735 DOI: 10.1021/Sb200010W  0.763
2012 Johnston CA, Doe CQ, Prehoda KE. Structure of an enzyme-derived phosphoprotein recognition domain. Plos One. 7: e36014. PMID 22545154 DOI: 10.1371/Journal.Pone.0036014  0.675
2012 Graybill C, Wee B, Atwood SX, Prehoda KE. Partitioning-defective protein 6 (Par-6) activates atypical protein kinase C (aPKC) by pseudosubstrate displacement. The Journal of Biological Chemistry. 287: 21003-11. PMID 22544755 DOI: 10.1074/Jbc.M112.360495  0.759
2012 Mauser JF, Prehoda KE. Inscuteable regulates the Pins-Mud spindle orientation pathway. Plos One. 7: e29611. PMID 22253744 DOI: 10.1371/Journal.Pone.0029611  0.787
2011 Wee B, Johnston CA, Prehoda KE, Doe CQ. Canoe binds RanGTP to promote Pins(TPR)/Mud-mediated spindle orientation. The Journal of Cell Biology. 195: 369-76. PMID 22024168 DOI: 10.1083/Jcb.201102130  0.651
2011 Johnston CA, Whitney DS, Volkman BF, Doe CQ, Prehoda KE. Conversion of the enzyme guanylate kinase into a mitotic-spindle orienting protein by a single mutation that inhibits GMP-induced closing. Proceedings of the National Academy of Sciences of the United States of America. 108: E973-8. PMID 21990344 DOI: 10.1073/Pnas.1104365108  0.647
2011 Connell M, Cabernard C, Ricketson D, Doe CQ, Prehoda KE. Asymmetric cortical extension shifts cleavage furrow position in Drosophila neuroblasts. Molecular Biology of the Cell. 22: 4220-6. PMID 21937716 DOI: 10.1091/Mbc.E11-02-0173  0.746
2011 Smith NR, Prehoda KE. Robust spindle alignment in Drosophila neuroblasts by ultrasensitive activation of pins. Molecular Cell. 43: 540-9. PMID 21855794 DOI: 10.1016/J.Molcel.2011.06.030  0.555
2010 Ricketson D, Johnston CA, Prehoda KE. Multiple tail domain interactions stabilize nonmuscle myosin II bipolar filaments. Proceedings of the National Academy of Sciences of the United States of America. 107: 20964-9. PMID 21078954 DOI: 10.1073/Pnas.1007025107  0.764
2010 Ségalen M, Johnston CA, Martin CA, Dumortier JG, Prehoda KE, David NB, Doe CQ, Bellaïche Y. The Fz-Dsh planar cell polarity pathway induces oriented cell division via Mud/NuMA in Drosophila and zebrafish. Developmental Cell. 19: 740-52. PMID 21074723 DOI: 10.1016/J.Devcel.2010.10.004  0.672
2010 Cabernard C, Prehoda KE, Doe CQ. A spindle-independent cleavage furrow positioning pathway. Nature. 467: 91-4. PMID 20811457 DOI: 10.1038/Nature09334  0.518
2010 Prehoda KE, Bowerman B. Cell polarity: keeping worms LeGaL. Current Biology : Cb. 20: R646-8. PMID 20692616 DOI: 10.1016/J.Cub.2010.06.011  0.491
2009 Prehoda KE. Polarization of Drosophila neuroblasts during asymmetric division. Cold Spring Harbor Perspectives in Biology. 1: a001388. PMID 20066083 DOI: 10.1101/Cshperspect.A001388  0.547
2009 Marcette J, Hood IV, Johnston CA, Doe CQ, Prehoda KE. Allosteric control of regulated scaffolding in membrane-associated guanylate kinases. Biochemistry. 48: 10014-9. PMID 19769408 DOI: 10.1021/Bi901160F  0.691
2009 Johnston CA, Hirono K, Prehoda KE, Doe CQ. Identification of an Aurora-A/PinsLINKER/Dlg spindle orientation pathway using induced cell polarity in S2 cells. Cell. 138: 1150-63. PMID 19766567 DOI: 10.1016/J.Cell.2009.07.041  0.683
2009 Atwood SX, Prehoda KE. aPKC phosphorylates Miranda to polarize fate determinants during neuroblast asymmetric cell division. Current Biology : Cb. 19: 723-9. PMID 19375318 DOI: 10.1016/J.Cub.2009.03.056  0.752
2009 Newman RA, Prehoda KE. Intramolecular interactions between the SRC homology 3 and guanylate kinase domains of discs large regulate its function in asymmetric cell division. The Journal of Biological Chemistry. 284: 12924-32. PMID 19261607 DOI: 10.1074/Jbc.M809304200  0.553
2008 Liu SL, Fewkes N, Ricketson D, Penkert RR, Prehoda KE. Filament-dependent and -independent localization modes of Drosophila non-muscle myosin II. The Journal of Biological Chemistry. 283: 380-7. PMID 17989074 DOI: 10.1074/Jbc.M703924200  0.782
2007 Nipper RW, Siller KH, Smith NR, Doe CQ, Prehoda KE. Galphai generates multiple Pins activation states to link cortical polarity and spindle orientation in Drosophila neuroblasts. Proceedings of the National Academy of Sciences of the United States of America. 104: 14306-11. PMID 17726110 DOI: 10.1073/Pnas.0701812104  0.558
2007 Atwood SX, Chabu C, Penkert RR, Doe CQ, Prehoda KE. Cdc42 acts downstream of Bazooka to regulate neuroblast polarity through Par-6 aPKC. Journal of Cell Science. 120: 3200-6. PMID 17726059 DOI: 10.1242/Jcs.014902  0.743
2007 Peterson FC, Deng Q, Zettl M, Prehoda KE, Lim WA, Way M, Volkman BF. Multiple WASP-interacting protein recognition motifs are required for a functional interaction with N-WASP. The Journal of Biological Chemistry. 282: 8446-53. PMID 17229736 DOI: 10.1074/Jbc.M609902200  0.527
2006 Qian Y, Prehoda KE. Interdomain interactions in the tumor suppressor discs large regulate binding to the synaptic protein GukHolder. The Journal of Biological Chemistry. 281: 35757-63. PMID 16982606 DOI: 10.1074/Jbc.M607057200  0.635
2005 Papayannopoulos V, Co C, Prehoda KE, Snapper S, Taunton J, Lim WA. A polybasic motif allows N-WASP to act as a sensor of PIP(2) density. Molecular Cell. 17: 181-91. PMID 15664188 DOI: 10.1016/J.Molcel.2004.11.054  0.43
2004 Penkert RR, DiVittorio HM, Prehoda KE. Internal recognition through PDZ domain plasticity in the Par-6-Pals1 complex. Nature Structural & Molecular Biology. 11: 1122-7. PMID 15475968 DOI: 10.1038/Nsmb839  0.52
2004 McGee AW, Nunziato DA, Maltez JM, Prehoda KE, Pitt GS, Bredt DS. Calcium channel function regulated by the SH3-GK module in beta subunits. Neuron. 42: 89-99. PMID 15066267 DOI: 10.1016/S0896-6273(04)00149-7  0.373
2004 Peterson FC, Penkert RR, Volkman BF, Prehoda KE. Cdc42 regulates the Par-6 PDZ domain through an allosteric CRIB-PDZ transition. Molecular Cell. 13: 665-76. PMID 15023337 DOI: 10.1016/S1097-2765(04)00086-3  0.568
2002 Volkman BF, Prehoda KE, Scott JA, Peterson FC, Lim WA. Structure of the N-WASP EVH1 domain-WIP complex: insight into the molecular basis of Wiskott-Aldrich Syndrome. Cell. 111: 565-76. PMID 12437929 DOI: 10.1016/S0092-8674(02)01076-0  0.505
2002 Prehoda KE, Lim WA. How signaling proteins integrate multiple inputs: a comparison of N-WASP and Cdk2. Current Opinion in Cell Biology. 14: 149-54. PMID 11891112 DOI: 10.1016/S0955-0674(02)00307-1  0.42
2001 McGee AW, Dakoji SR, Olsen O, Bredt DS, Lim WA, Prehoda KE. Structure of the SH3-guanylate kinase module from PSD-95 suggests a mechanism for regulated assembly of MAGUK scaffolding proteins. Molecular Cell. 8: 1291-301. PMID 11779504 DOI: 10.1016/S1097-2765(01)00411-7  0.508
2001 Prehoda KE, Lim WA. The double life of PX domains. Nature Structural Biology. 8: 570-2. PMID 11427879 DOI: 10.1038/89586  0.518
2000 Prehoda KE, Scott JA, Mullins RD, Lim WA. Integration of multiple signals through cooperative regulation of the N-WASP-Arp2/3 complex. Science (New York, N.Y.). 290: 801-6. PMID 11052943 DOI: 10.1126/Science.290.5492.801  0.525
1999 Prehoda KE, Lee DJ, Lim WA. Structure of the enabled/VASP homology 1 domain-peptide complex: a key component in the spatial control of actin assembly. Cell. 97: 471-80. PMID 10338211 DOI: 10.1016/S0092-8674(00)80757-6  0.546
1999 Hillier BJ, Christopherson KS, Prehoda KE, Bredt DS, Lim WA. Unexpected modes of PDZ domain scaffolding revealed by structure of nNOS-syntrophin complex. Science (New York, N.Y.). 284: 812-5. PMID 10221915 DOI: 10.1126/Science.284.5415.812  0.508
1998 Prehoda KE, Mooberry ES, Markley JL. Pressure denaturation of proteins: evaluation of compressibility effects. Biochemistry. 37: 5785-90. PMID 9558311 DOI: 10.1021/Bi980384U  0.486
1997 Chivers PT, Prehoda KE, Volkman BF, Kim BM, Markley JL, Raines RT. Microscopic pKa values of Escherichia coli thioredoxin. Biochemistry. 36: 14985-91. PMID 9398223 DOI: 10.1021/Bi970071J  0.576
1997 Chivers PT, Prehoda KE, Raines RT. The CXXC motif: a rheostat in the active site. Biochemistry. 36: 4061-6. PMID 9099998 DOI: 10.1021/Bi9628580  0.437
1996 Truckses DM, Somoza JR, Prehoda KE, Miller SC, Markley JL. Coupling between trans/cis proline isomerization and protein stability in staphylococcal nuclease. Protein Science : a Publication of the Protein Society. 5: 1907-16. PMID 8880915 DOI: 10.1002/Pro.5560050917  0.769
1996 Prehoda KE, Loh SN, Markley JL. Modeling Volume Changes in Proteins Using Partial Molar Volumes of Model Compounds Techniques in Protein Chemistry. 7: 433-438. DOI: 10.1016/S1080-8914(96)80047-0  0.644
1994 Markley JL, Prehoda K, Truckses D, Wang J, Hinck AP, Loh SN, Walkenhorst WF. Case study of protein structure, stability, and function: NMR investigations of the proline residues in staphylococcal nuclease Pure and Applied Chemistry. 66: 65-69. DOI: 10.1351/Pac199466010065  0.716
1994 Loh SN, Prehoda KE, Wang J, Markley JL. Measuring Global and Local Structural Free Energy Changes in Staphylococcal Nuclease by NMR-Observed Hydrogen Exchange Techniques in Protein Chemistry. 5: 431-438. DOI: 10.1016/B978-0-12-194710-1.50053-9  0.712
1993 Royer CA, Hinck AP, Loh SN, Prehoda KE, Peng X, Jonas J, Markley JL. Effects of amino acid substitutions on the pressure denaturation of staphylococcal nuclease as monitored by fluorescence and nuclear magnetic resonance spectroscopy. Biochemistry. 32: 5222-32. PMID 8494899 DOI: 10.1021/Bi00070A034  0.758
1993 Loh SN, Prehoda KE, Wang J, Markley JL. Hydrogen exchange in unligated and ligated staphylococcal nuclease. Biochemistry. 32: 11022-8. PMID 8218167 DOI: 10.1021/Bi00092A011  0.692
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