Carolyn Coyne - Publications

Affiliations: 
Cell Biology University of Pittsburgh, Pittsburgh, PA, United States 
Area:
Virology Biology, Cell Biology

93 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Cabo LF, Yang L, Gao M, da Silva RJ, Washington NN, Reilly SM, Megli CJ, Coyne CB, Boyle JP. infection misdirects placental trophoblast lineage specification. Biorxiv : the Preprint Server For Biology. PMID 39314453 DOI: 10.1101/2024.09.10.612241  0.395
2024 da Silva RJ, Cabo LF, George JL, Cahoon LA, Yang L, Coyne CB, Boyle JP. The trophoblast surface becomes refractory to adhesion by congenitally transmitted and during cytotrophoblast to syncytiotrophoblast development. Msphere. e0074823. PMID 38771057 DOI: 10.1128/msphere.00748-23  0.315
2023 da Silva RJ, Cabo LF, George JL, Cahoon LA, Yang L, Coyne CB, Boyle JP. Human trophoblast stem cells can be used to model placental susceptibility to and highlight the critical importance of the trophoblast cell surface in pathogen resistance. Biorxiv : the Preprint Server For Biology. PMID 37986837 DOI: 10.1101/2023.11.10.566663  0.348
2023 Semmes EC, Nettere DR, Nelson AN, Hurst JH, Cain D, Burt TD, Kurtzberg J, Reeves RK, Coyne CB, Fouda GG, Pollara J, Permar SR, Walsh KM. In utero human cytomegalovirus infection expands NK cell-like FcγRIII-expressing CD8+ T cells that mediate antibody-dependent functions. Medrxiv : the Preprint Server For Health Sciences. PMID 37745390 DOI: 10.1101/2023.09.08.23295279  0.318
2022 Trimarco JD, Nelson SL, Chaparian RR, Wells AI, Murray NB, Azadi P, Coyne CB, Heaton NS. Cellular glycan modification by B3GAT1 broadly restricts influenza virus infection. Nature Communications. 13: 6456. PMID 36309510 DOI: 10.1038/s41467-022-34111-0  0.335
2022 Frank JA, Singh M, Cullen HB, Kirou RA, Benkaddour-Boumzaouad M, Cortes JL, Garcia Pérez J, Coyne CB, Feschotte C. Evolution and antiviral activity of a human protein of retroviral origin. Science (New York, N.Y.). 378: 422-428. PMID 36302021 DOI: 10.1126/science.abq7871  0.337
2022 Yang L, Semmes EC, Ovies C, Megli C, Permar S, Gilner JB, Coyne CB. Innate immune signaling in trophoblast and decidua organoids defines differential antiviral defenses at the maternal-fetal interface. Elife. 11. PMID 35975985 DOI: 10.7554/eLife.79794  0.381
2022 Wells AI, Coyne CB. An Model of Echovirus-Induced Meningitis Defines the Differential Roles of Type I and Type III Interferon Signaling in Central Nervous System Infection. Journal of Virology. 96: e0033022. PMID 35699446 DOI: 10.1128/jvi.00330-22  0.343
2022 Wells AI, Grimes KA, Coyne CB. Enterovirus Replication and Dissemination Are Differentially Controlled by Type I and III Interferons in the Gastrointestinal Tract. Mbio. e0044322. PMID 35604122 DOI: 10.1128/mbio.00443-22  0.363
2021 Rudzki EN, Ander SE, Coombs RS, Alrubaye HS, Cabo LF, Blank ML, Gutiérrez-Melo N, Dubey JP, Coyne CB, Boyle JP. Toxoplasma gondii Is Required for Placenta-Specific Induction of the Regulatory Chemokine CCL22 in Human and Mouse. Mbio. 12: e0159121. PMID 34781732 DOI: 10.1128/mBio.01591-21  0.816
2021 Megli CJ, Coyne CB. Infections at the maternal-fetal interface: an overview of pathogenesis and defence. Nature Reviews. Microbiology. PMID 34433930 DOI: 10.1038/s41579-021-00610-y  0.382
2021 Roberts DJ, Edlow AG, Romero RJ, Coyne CB, Ting DT, Hornick JL, Zaki SR, Adhikari UD, Serghides L, Gaw SL, Metz TD. SPECIAL REPORT: A standardized definition of placental infection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a consensus statement from the National Institutes of Health/Eunice Kennedy Shriver National Institute of Child Health and Human Development (NIH/NICHD) SARS-CoV-2 placental infection workshop. American Journal of Obstetrics and Gynecology. PMID 34364845 DOI: 10.1016/j.ajog.2021.07.029  0.353
2021 Wells AI, Grimes KA, Kim K, Branche E, Bakkenist CJ, DePas WH, Shresta S, Coyne CB. Human FcRn expression and Type I Interferon signaling control Echovirus 11 pathogenesis in mice. Plos Pathogens. 17: e1009252. PMID 33513208 DOI: 10.1371/journal.ppat.1009252  0.305
2021 Megli C, Morosky S, Rajasundaram D, Coyne CB. Inflammasome signaling in human placental trophoblasts regulates immune defense against Listeria monocytogenes infection. The Journal of Experimental Medicine. 218. PMID 32976558 DOI: 10.1084/jem.20200649  0.327
2020 Evans AS, Lennemann NJ, Coyne CB. BPIFB3 interacts with ARFGAP1 and TMED9 to regulate non-canonical autophagy and RNA virus infection. Journal of Cell Science. PMID 34005375 DOI: 10.1242/jcs.251835  0.354
2020 Evans AS, Lennemann NJ, Coyne CB. BPIFB3 interacts with ARFGAP1 and TMED9 to regulate non-canonical autophagy and RNA virus infection. Journal of Cell Science. PMID 33277377 DOI: 10.1242/jcs.251835  0.776
2020 Ferrari M, Zevini A, Palermo E, Muscolini M, Alexandridi M, Etna MP, Coccia EM, Fernandez-Sesma A, Coyne C, Zhang D, Marques ETA, Olagnier D, Hiscott J. Dengue virus targets Nrf2 for NS2B3-mediated degradation leading to enhanced oxidative stress and viral replication. Journal of Virology. PMID 32999020 DOI: 10.1128/JVI.01551-20  0.316
2020 Lennemann NJ, Evans AS, Coyne CB. Imaging-Based Reporter Systems to Define CVB-Induced Membrane Remodeling in Living Cells. Viruses. 12. PMID 32992749 DOI: 10.3390/v12101074  0.787
2020 Evans AS, Lennemann NJ, Coyne CB. BPIFB3 regulates ER morphology to facilitate flavivirus replication. Journal of Virology. PMID 32102874 DOI: 10.1128/JVI.00029-20  0.79
2020 Kim AS, Zimmerman O, Fox JM, Nelson CA, Basore K, Zhang R, Durnell L, Desai C, Bullock C, Deem SL, Oppenheimer J, Shapiro B, Wang T, Cherry S, Coyne CB, et al. An Evolutionary Insertion in the Mxra8 Receptor-Binding Site Confers Resistance to Alphavirus Infection and Pathogenesis. Cell Host & Microbe. PMID 32075743 DOI: 10.1016/J.Chom.2020.01.008  0.36
2019 Wells AI, Coyne CB. Enteroviruses: A Gut-Wrenching Game of Entry, Detection, and Evasion. Viruses. 11. PMID 31117206 DOI: 10.3390/v11050460  0.329
2019 Good C, Wells AI, Coyne CB. Type III interferon signaling restricts enterovirus 71 infection of goblet cells. Science Advances. 5: eaau4255. PMID 30854425 DOI: 10.1126/sciadv.aau4255  0.41
2019 Morosky S, Wells AI, Lemon K, Evans AS, Schamus S, Bakkenist CJ, Coyne CB. The neonatal Fc receptor is a pan-echovirus receptor. Proceedings of the National Academy of Sciences of the United States of America. 116: 3758-3763. PMID 30808762 DOI: 10.1073/Pnas.1817341116  0.355
2019 Caine EA, Scheaffer SM, Arora N, Zaitsev K, Artyomov MN, Coyne CB, Moley KH, Diamond MS. Interferon lambda protects the female reproductive tract against Zika virus infection. Nature Communications. 10: 280. PMID 30655513 DOI: 10.1038/S41467-018-07993-2  0.679
2019 Ander SE, Diamond MS, Coyne CB. Immune responses at the maternal-fetal interface. Science Immunology. 4. PMID 30635356 DOI: 10.1126/Sciimmunol.Aat6114  0.787
2019 Ouyang Y, Li H, Krawczynski K, Mouillet J, Coyne C, Sorkin A, Sadovsky Y. B-101 Placental exosomes in maternal-placental-fetal communication and viral resistance Jaids Journal of Acquired Immune Deficiency Syndromes. 81: 35. DOI: 10.1097/01.Qai.0000557950.13625.84  0.342
2018 McMillen CM, Arora N, Boyles DA, Albe JR, Kujawa MR, Bonadio JF, Coyne CB, Hartman AL. Rift Valley fever virus induces fetal demise in Sprague-Dawley rats through direct placental infection. Science Advances. 4: eaau9812. PMID 30525107 DOI: 10.1126/Sciadv.Aau9812  0.711
2018 Zimmerman MG, Quicke KM, O'Neal JT, Arora N, Machiah D, Priyamvada L, Kauffman RC, Register E, Adekunle O, Swieboda D, Johnson EL, Cordes S, Haddad L, Chakraborty R, Coyne CB, et al. Cross-Reactive Dengue Virus Antibodies Augment Zika Virus Infection of Human Placental Macrophages. Cell Host & Microbe. 24: 731-742.e6. PMID 30439342 DOI: 10.1016/J.Chom.2018.10.008  0.696
2018 Wells AI, Coyne CB. Type III Interferons in Antiviral Defenses at Barrier Surfaces. Trends in Immunology. PMID 30219309 DOI: 10.1016/j.it.2018.08.008  0.328
2018 Delorme-Axford E, Abernathy E, Lennemann NJ, Bernard A, Ariosa A, Coyne CB, Kirkegaard K, Klionsky DJ. The Exoribonuclease Xrn1 Is a Post-Transcriptional Negative Regulator of Autophagy. Autophagy. 1-47. PMID 29465287 DOI: 10.1080/15548627.2018.1441648  0.769
2018 Platt DJ, Smith AM, Arora N, Diamond MS, Coyne CB, Miner JJ. Zika virus-related neurotropic flaviviruses infect human placental explants and cause fetal demise in mice. Science Translational Medicine. 10. PMID 29386359 DOI: 10.1126/Scitranslmed.Aao7090  0.716
2018 Ander SE, Rudzki EN, Arora N, Sadovsky Y, Coyne CB, Boyle JP. Human Placental Syncytiotrophoblasts Restrict Toxoplasma gondii Attachment and Replication and Respond to Infection by Producing Immunomodulatory Chemokines. Mbio. 9. PMID 29317509 DOI: 10.1128/Mbio.01678-17  0.816
2018 Yockey LJ, Jurado KA, Arora N, Millet A, Rakib T, Milano KM, Hastings AK, Fikrig E, Kong Y, Horvath TL, Weatherbee S, Kliman HJ, Coyne CB, Iwasaki A. Type I interferons instigate fetal demise after Zika virus infection. Science Immunology. 3. PMID 29305462 DOI: 10.1126/Sciimmunol.Aao1680  0.709
2018 Bayer A, Lennemann NJ, Ouyang Y, Sadovsky E, Sheridan MA, Roberts RM, Coyne CB, Sadovsky Y. Chromosome 19 microRNAs exert antiviral activity independent from type III interferon signaling. Placenta. 61: 33-38. PMID 29277269 DOI: 10.1016/J.Placenta.2017.11.004  0.816
2017 Jagger BW, Miner JJ, Cao B, Arora N, Smith AM, Kovacs A, Mysorekar IU, Coyne CB, Diamond MS. Gestational Stage and IFN-λ Signaling Regulate ZIKV Infection In Utero. Cell Host & Microbe. 22: 366-376.e3. PMID 28910635 DOI: 10.1016/J.Chom.2017.08.012  0.705
2017 Corry J, Arora N, Good CA, Sadovsky Y, Coyne CB. Organotypic models of type III interferon-mediated protection from Zika virus infections at the maternal-fetal interface. Proceedings of the National Academy of Sciences of the United States of America. PMID 28784796 DOI: 10.1073/pnas.1707513114  0.831
2017 Bramley JC, Drummond CG, Lennemann NJ, Good CA, Kim KS, Coyne CB. A Three-Dimensional Cell Culture System To Model RNA Virus Infections at the Blood-Brain Barrier. Msphere. 2. PMID 28656176 DOI: 10.1128/mSphere.00206-17  0.805
2017 Arora N, Sadovsky Y, Dermody TS, Coyne CB. Microbial Vertical Transmission during Human Pregnancy. Cell Host & Microbe. 21: 561-567. PMID 28494237 DOI: 10.1016/J.Chom.2017.04.007  0.695
2017 Dumont TMF, Mouillet JF, Bayer A, Gardner CL, Klimstra WB, Wolf DG, Yagel S, Balmir F, Binstock A, Sanfilippo JS, Coyne CB, Larkin JC, Sadovsky Y. The expression level of C19MC miRNAs in early pregnancy and in response to viral infection. Placenta. 53: 23-29. PMID 28487016 DOI: 10.1016/J.Placenta.2017.03.011  0.315
2017 Drummond CG, Bolock AM, Ma C, Luke CJ, Good M, Coyne CB. Enteroviruses infect human enteroids and induce antiviral signaling in a cell lineage-specific manner. Proceedings of the National Academy of Sciences of the United States of America. PMID 28137842 DOI: 10.1073/pnas.1617363114  0.829
2017 Lennemann NJ, Coyne CB. Dengue and Zika viruses subvert reticulophagy by NS2B3-mediated cleavage of FAM134B. Autophagy. 0. PMID 28102736 DOI: 10.1080/15548627.2016.1265192  0.783
2017 Rausch K, Hackett BA, Weinbren NL, Reeder SM, Sadovsky Y, Hunter CA, Schultz DC, Coyne CB, Cherry S. Screening Bioactives Reveals Nanchangmycin as a Broad Spectrum Antiviral Active against Zika Virus. Cell Reports. 18: 804-815. PMID 28099856 DOI: 10.1016/J.Celrep.2016.12.068  0.362
2016 Ouyang Y, Bayer A, Chu T, Tyurin VA, Kagan VE, Morelli AE, Coyne CB, Sadovsky Y. Isolation of human trophoblastic extracellular vesicles and characterization of their cargo and antiviral activity. Placenta. 47: 86-95. PMID 27780544 DOI: 10.1016/J.Placenta.2016.09.008  0.763
2016 Coyne CB, Lazear HM. Zika virus - reigniting the TORCH. Nature Reviews. Microbiology. PMID 27573577 DOI: 10.1038/nrmicro.2016.125  0.385
2016 Olagnier D, Muscolini M, Coyne CB, Diamond MS, Hiscott J. Mechanisms of Zika Virus Infection and Neuropathogenesis. Dna and Cell Biology. PMID 27348136 DOI: 10.1089/Dna.2016.3404  0.352
2016 Drummond CG, Nickerson CA, Coyne CB. A Three-Dimensional Cell Culture Model To Study Enterovirus Infection of Polarized Intestinal Epithelial Cells. Msphere. 1. PMID 27303677 DOI: 10.1128/mSphere.00030-15  0.809
2016 Bayer A, Lennemann NJ, Ouyang Y, Bramley JC, Morosky S, Marques ET, Cherry S, Sadovsky Y, Coyne CB. Type III Interferons Produced by Human Placental Trophoblasts Confer Protection against Zika Virus Infection. Cell Host & Microbe. PMID 27066743 DOI: 10.1016/J.Chom.2016.03.008  0.834
2016 Cuevas RA, Ghosh A, Wallerath C, Hornung V, Coyne CB, Sarkar SN. MOV10 Provides Antiviral Activity against RNA Viruses by Enhancing RIG-I-MAVS-Independent IFN Induction. Journal of Immunology (Baltimore, Md. : 1950). PMID 27016603 DOI: 10.4049/Jimmunol.1501359  0.303
2016 McConkey CA, Delorme-Axford E, Nickerson CA, Kim KS, Sadovsky Y, Boyle JP, Coyne CB. A three-dimensional culture system recapitulates placental syncytiotrophoblast development and microbial resistance. Science Advances. 2: e1501462. PMID 26973875 DOI: 10.1126/Sciadv.1501462  0.757
2016 Morosky S, Lennemann NJ, Coyne CB. BPIFB6 regulates secretory pathway trafficking and enterovirus replication. Journal of Virology. PMID 26962226 DOI: 10.1128/JVI.00170-16  0.763
2016 Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Coyne CB, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222. PMID 26799652 DOI: 10.1080/15548627.2015.1100356  0.686
2016 Hendricks MR, Lashua LP, Fischer DK, Flitter BA, Eichinger KM, Durbin JE, Sarkar SN, Coyne CB, Empey KM, Bomberger JM. Respiratory syncytial virus infection enhances Pseudomonas aeruginosa biofilm growth through dysregulation of nutritional immunity. Proceedings of the National Academy of Sciences of the United States of America. PMID 26729873 DOI: 10.1073/Pnas.1516979113  0.326
2016 Ouyang Y, Bayer A, Chu T, Tyurin V, Kagan V, Morelli AE, Coyne CB, Sadovsky Y. Isolation of human trophoblastic extracellular vesicles and characterization of their cargo and antiviral activity Placenta. 47: 86-95. DOI: 10.1016/j.placenta.2016.09.008  0.771
2015 Shu Q, Lennemann NJ, Sarkar SN, Sadovsky Y, Coyne CB. ADAP2 Is an Interferon Stimulated Gene That Restricts RNA Virus Entry. Plos Pathogens. 11: e1005150. PMID 26372645 DOI: 10.1371/Journal.Ppat.1005150  0.771
2015 Harris KG, Morosky SA, Drummond CG, Patel M, Kim C, Stolz DB, Bergelson JM, Cherry S, Coyne CB. RIP3 Regulates Autophagy and Promotes Coxsackievirus B3 Infection of Intestinal Epithelial Cells. Cell Host & Microbe. 18: 221-32. PMID 26269957 DOI: 10.1016/J.Chom.2015.07.007  0.817
2015 Sadovsky Y, Mouillet JF, Ouyang Y, Bayer A, Coyne CB. The Function of TrophomiRs and Other MicroRNAs in the Human Placenta. Cold Spring Harbor Perspectives in Medicine. 5: a023036. PMID 25877393 DOI: 10.1101/Cshperspect.A023036  0.762
2015 Lennemann NJ, Coyne CB. Catch me if you can: the link between autophagy and viruses. Plos Pathogens. 11: e1004685. PMID 25811485 DOI: 10.1371/journal.ppat.1004685  0.732
2015 Bayer A, Delorme-Axford E, Sleigher C, Frey TK, Trobaugh DW, Klimstra WB, Emert-Sedlak LA, Smithgall TE, Kinchington PR, Vadia S, Seveau S, Boyle JP, Coyne CB, Sadovsky Y. Human trophoblasts confer resistance to viruses implicated in perinatal infection. American Journal of Obstetrics and Gynecology. 212: 71.e1-8. PMID 25108145 DOI: 10.1016/J.Ajog.2014.07.060  0.823
2015 Ouyang Y, Mouillet J, Chang G, Chu T, Sadovsky E, Bayer A, Mishima T, Coyne CB, Sadovsky Y. MiRNA trafficking across the maternal-placental-fetal compartments Placenta. 36: 481. DOI: 10.1016/J.Placenta.2015.01.422  0.744
2014 Delorme-Axford E, Sadovsky Y, Coyne CB. The Placenta as a Barrier to Viral Infections. Annual Review of Virology. 1: 133-46. PMID 26958718 DOI: 10.1146/Annurev-Virology-031413-085524  0.758
2014 Delorme-Axford E, Morosky S, Bomberger J, Stolz DB, Jackson WT, Coyne CB. BPIFB3 regulates autophagy and coxsackievirus B replication through a noncanonical pathway independent of the core initiation machinery. Mbio. 5: e02147. PMID 25491355 DOI: 10.1128/Mbio.02147-14  0.738
2014 Mouillet JF, Ouyang Y, Bayer A, Coyne CB, Sadovsky Y. The role of trophoblastic microRNAs in placental viral infection. The International Journal of Developmental Biology. 58: 281-9. PMID 25023694 DOI: 10.1387/Ijdb.130349Ys  0.772
2014 Zhu J, Zhang Y, Ghosh A, Cuevas RA, Forero A, Dhar J, Ibsen MS, Schmid-Burgk JL, Schmidt T, Ganapathiraju MK, Fujita T, Hartmann R, Barik S, Hornung V, Coyne CB, et al. Antiviral activity of human OASL protein is mediated by enhancing signaling of the RIG-I RNA sensor. Immunity. 40: 936-48. PMID 24931123 DOI: 10.1016/J.Immuni.2014.05.007  0.345
2014 Jacobs JL, Zhu J, Sarkar SN, Coyne CB. Regulation of mitochondrial antiviral signaling (MAVS) expression and signaling by the mitochondria-associated endoplasmic reticulum membrane (MAM) protein Gp78. The Journal of Biological Chemistry. 289: 1604-16. PMID 24285545 DOI: 10.1074/Jbc.M113.520254  0.685
2014 Ouyang Y, Mouillet J, Chang G, Chu T, Sadovsky E, Bayer A, Mishima T, Coyne C, Sadovsky Y. MiRNA nano-packages for maternal-placental-fetal communication Placenta. 35: A5. DOI: 10.1016/J.Placenta.2014.06.016  0.781
2013 Delorme-Axford E, Bayer A, Sadovsky Y, Coyne CB. Autophagy as a mechanism of antiviral defense at the maternal-fetal interface. Autophagy. 9: 2173-4. PMID 24231730 DOI: 10.4161/Auto.26558  0.828
2013 Jacobs JL, Coyne CB. Mechanisms of MAVS regulation at the mitochondrial membrane. Journal of Molecular Biology. 425: 5009-19. PMID 24120683 DOI: 10.1016/j.jmb.2013.10.007  0.681
2013 Bergelson JM, Coyne CB. Picornavirus entry. Advances in Experimental Medicine and Biology. 790: 24-41. PMID 23884584 DOI: 10.1007/978-1-4614-7651-1_2  0.639
2013 Delorme-Axford E, Donker RB, Mouillet JF, Chu T, Bayer A, Ouyang Y, Wang T, Stolz DB, Sarkar SN, Morelli AE, Sadovsky Y, Coyne CB. Human placental trophoblasts confer viral resistance to recipient cells. Proceedings of the National Academy of Sciences of the United States of America. 110: 12048-53. PMID 23818581 DOI: 10.1073/Pnas.1304718110  0.821
2013 Harris KG, Coyne CB. Enter at your own risk: how enteroviruses navigate the dangerous world of pattern recognition receptor signaling. Cytokine. 63: 230-6. PMID 23764548 DOI: 10.1016/j.cyto.2013.05.007  0.401
2013 Delorme-Axford E, Sadovsky Y, Coyne CB. Lipid raft- and SRC family kinase-dependent entry of coxsackievirus B into human placental trophoblasts. Journal of Virology. 87: 8569-81. PMID 23720726 DOI: 10.1128/Jvi.00708-13  0.757
2012 Bozym RA, Delorme-Axford E, Harris K, Morosky S, Ikizler M, Dermody TS, Sarkar SN, Coyne CB. Focal adhesion kinase is a component of antiviral RIG-I-like receptor signaling. Cell Host & Microbe. 11: 153-66. PMID 22341464 DOI: 10.1016/J.Chom.2012.01.008  0.809
2011 Delorme-Axford E, Coyne CB. The actin cytoskeleton as a barrier to virus infection of polarized epithelial cells. Viruses. 3: 2462-77. PMID 22355449 DOI: 10.3390/V3122462  0.75
2011 Bozym RA, Patel K, White C, Cheung KH, Bergelson JM, Morosky SA, Coyne CB. Calcium signals and calpain-dependent necrosis are essential for release of coxsackievirus B from polarized intestinal epithelial cells. Molecular Biology of the Cell. 22: 3010-21. PMID 21737691 DOI: 10.1091/Mbc.E11-02-0094  0.809
2011 Morosky SA, Zhu J, Mukherjee A, Sarkar SN, Coyne CB. Retinoic acid-induced gene-I (RIG-I) associates with nucleotide-binding oligomerization domain-2 (NOD2) to negatively regulate inflammatory signaling. The Journal of Biological Chemistry. 286: 28574-83. PMID 21690088 DOI: 10.1074/Jbc.M111.227942  0.521
2011 Mukherjee A, Morosky SA, Delorme-Axford E, Dybdahl-Sissoko N, Oberste MS, Wang T, Coyne CB. The coxsackievirus B 3C protease cleaves MAVS and TRIF to attenuate host type I interferon and apoptotic signaling. Plos Pathogens. 7: e1001311. PMID 21436888 DOI: 10.1371/Journal.Ppat.1001311  0.768
2011 Coyne CB, Cherry S. RNAi screening in mammalian cells to identify novel host cell molecules involved in the regulation of viral infections. Methods in Molecular Biology (Clifton, N.J.). 721: 397-405. PMID 21431700 DOI: 10.1007/978-1-61779-037-9_25  0.343
2011 Coyne CB, Bozym R, Morosky SA, Hanna SL, Mukherjee A, Tudor M, Kim KS, Cherry S. Comparative RNAi screening reveals host factors involved in enterovirus infection of polarized endothelial monolayers. Cell Host & Microbe. 9: 70-82. PMID 21238948 DOI: 10.1016/J.Chom.2011.01.001  0.823
2010 Bozym RA, Morosky SA, Kim KS, Cherry S, Coyne CB. Release of intracellular calcium stores facilitates coxsackievirus entry into polarized endothelial cells. Plos Pathogens. 6: e1001135. PMID 20949071 DOI: 10.1371/Journal.Ppat.1001135  0.775
2010 Moser TS, Jones RG, Thompson CB, Coyne CB, Cherry S. A kinome RNAi screen identified AMPK as promoting poxvirus entry through the control of actin dynamics. Plos Pathogens. 6: e1000954. PMID 20585561 DOI: 10.1371/Journal.Ppat.1000954  0.376
2009 Patel KP, Coyne CB, Bergelson JM. Dynamin- and lipid raft-dependent entry of decay-accelerating factor (DAF)-binding and non-DAF-binding coxsackieviruses into nonpolarized cells. Journal of Virology. 83: 11064-77. PMID 19710132 DOI: 10.1128/Jvi.01016-09  0.759
2009 Mukherjee A, Morosky SA, Shen L, Weber CR, Turner JR, Kim KS, Wang T, Coyne CB. Retinoic acid-induced gene-1 (RIG-I) associates with the actin cytoskeleton via caspase activation and recruitment domain-dependent interactions. The Journal of Biological Chemistry. 284: 6486-94. PMID 19122199 DOI: 10.1074/Jbc.M807547200  0.503
2007 Coyne CB, Shen L, Turner JR, Bergelson JM. Coxsackievirus entry across epithelial tight junctions requires occludin and the small GTPases Rab34 and Rab5. Cell Host & Microbe. 2: 181-92. PMID 18005733 DOI: 10.1016/J.Chom.2007.07.003  0.638
2007 Coyne CB, Kim KS, Bergelson JM. Poliovirus entry into human brain microvascular cells requires receptor-induced activation of SHP-2. The Embo Journal. 26: 4016-28. PMID 17717529 DOI: 10.1038/Sj.Emboj.7601831  0.668
2006 Cherry S, Kunte A, Wang H, Coyne C, Rawson RB, Perrimon N. COPI activity coupled with fatty acid biosynthesis is required for viral replication. Plos Pathogens. 2: e102. PMID 17040126 DOI: 10.1371/Journal.Ppat.0020102  0.378
2006 Coyne CB, Bergelson JM. Virus-induced Abl and Fyn kinase signals permit coxsackievirus entry through epithelial tight junctions. Cell. 124: 119-31. PMID 16413486 DOI: 10.1016/J.Cell.2005.10.035  0.659
2005 Coyne CB, Bergelson JM. CAR: a virus receptor within the tight junction. Advanced Drug Delivery Reviews. 57: 869-82. PMID 15820557 DOI: 10.1016/J.Addr.2005.01.007  0.661
2004 Coyne CB, Voelker T, Pichla SL, Bergelson JM. The coxsackievirus and adenovirus receptor interacts with the multi-PDZ domain protein-1 (MUPP-1) within the tight junction. The Journal of Biological Chemistry. 279: 48079-84. PMID 15364909 DOI: 10.1074/Jbc.M409061200  0.579
2003 Coyne CB, Gambling TM, Boucher RC, Carson JL, Johnson LG. Role of claudin interactions in airway tight junctional permeability. American Journal of Physiology. Lung Cellular and Molecular Physiology. 285: L1166-78. PMID 12909588 DOI: 10.1152/Ajplung.00182.2003  0.615
2003 Johnson LG, Vanhook MK, Coyne CB, Haykal-Coates N, Gavett SH. Safety and efficiency of modulating paracellular permeability to enhance airway epithelial gene transfer in vivo. Human Gene Therapy. 14: 729-47. PMID 12804137 DOI: 10.1089/104303403765255138  0.582
2003 Coyne CB, Ribeiro CM, Boucher RC, Johnson LG. Acute mechanism of medium chain fatty acid-induced enhancement of airway epithelial permeability. The Journal of Pharmacology and Experimental Therapeutics. 305: 440-50. PMID 12606647 DOI: 10.1124/Jpet.102.047654  0.599
2002 Coyne CB, Vanhook MK, Gambling TM, Carson JL, Boucher RC, Johnson LG. Regulation of airway tight junctions by proinflammatory cytokines. Molecular Biology of the Cell. 13: 3218-34. PMID 12221127 DOI: 10.1091/Mbc.E02-03-0134  0.588
2000 Coyne CB, Kelly MM, Boucher RC, Johnson LG. Enhanced epithelial gene transfer by modulation of tight junctions with sodium caprate. American Journal of Respiratory Cell and Molecular Biology. 23: 602-9. PMID 11062138 DOI: 10.1165/Ajrcmb.23.5.4164  0.61
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