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Jacklyn N. Hellwege, Ph.D. - Publications

Affiliations: 
2014 Molecular Genetics & Genomics Wake Forest University, Winston-Salem, NC, United States 
Area:
Genetics, Epidemiology
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36 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Siew ED, Hellwege JN, Hung AM, Birkelo BC, Vincz AJ, Parr SK, Denton J, Greevy RA, Robinson-Cohen C, Liu H, Susztak K, Matheny ME, Velez Edwards DR. Genome-Wide Association Study of Hospitalized Patients and Acute Kidney Injury. Kidney International. PMID 38797326 DOI: 10.1016/j.kint.2024.04.019  0.361
2024 Keaton JM, Kamali Z, Xie T, Vaez A, Williams A, Goleva SB, Ani A, Evangelou E, Hellwege JN, Yengo L, Young WJ, Traylor M, Giri A, Zheng Z, Zeng J, et al. Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits. Nature Genetics. PMID 38689001 DOI: 10.1038/s41588-024-01714-w  0.375
2024 Breeyear JH, Mautz BS, Keaton JM, Hellwege JN, Torstenson ES, Liang J, Bray MJ, Giri A, Warren HR, Munroe PB, Velez Edwards DR, Zhu X, Li C, Edwards TL. A new test for trait mean and variance detects unreported loci for blood-pressure variation. American Journal of Human Genetics. PMID 38614075 DOI: 10.1016/j.ajhg.2024.03.014  0.313
2023 Armstrong ND, Srinivasasainagendra V, Ammous F, Assimes TL, Beitelshees AL, Brody J, Cade BE, Ida Chen YD, Chen H, de Vries PS, Floyd JS, Franceschini N, Guo X, Hellwege JN, House JS, et al. Whole genome sequence analysis of apparent treatment resistant hypertension status in participants from the Trans-Omics for Precision Medicine program. Frontiers in Genetics. 14: 1278215. PMID 38162683 DOI: 10.3389/fgene.2023.1278215  0.609
2022 Piekos JA, Hellwege JN, Zhang Y, Torstenson ES, Jarvik GP, Dikilitas O, Kullo IJ, Schaid DJ, Crosslin DR, Pendergrass SA, Lee MTM, Roden D, Denny JC, Edwards TL, Velez Edwards DR. Uterine fibroid polygenic risk score (PRS) associates and predicts risk for uterine fibroid. Human Genetics. PMID 35226188 DOI: 10.1007/s00439-022-02442-z  0.326
2021 Keaton JM, Jasper EA, Hellwege JN, Jones SH, Torstenson ES, Edwards TL, Velez Edwards DR. Evidence that geographic variation in genetic ancestry associates with uterine fibroids. Human Genetics. PMID 34302236 DOI: 10.1007/s00439-021-02322-y  0.305
2020 Surendran P, Feofanova EV, Lahrouchi N, Ntalla I, Karthikeyan S, Cook J, Chen L, Mifsud B, Yao C, Kraja AT, Cartwright JH, Hellwege JN, Giri A, Tragante V, Thorleifsson G, et al. Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals. Nature Genetics. PMID 33230300 DOI: 10.1038/s41588-020-00713-x  0.413
2020 Mosley JD, Levinson RT, Farber-Eger E, Edwards TL, Hellwege JN, Hung AM, Giri A, Shuey MM, Shaffer CM, Shi M, Brittain EL, Chung WK, Kullo IJ, Arruda-Olson AM, Jarvik GP, et al. The polygenic architecture of left ventricular mass mirrors the clinical epidemiology. Scientific Reports. 10: 7561. PMID 32372017 DOI: 10.1038/S41598-020-64525-Z  0.373
2020 Kelly TN, Sun X, Brody JA, Gagliano SA, He KY, Hellwege JN. Abstract 46: Whole Genome Sequence Analysis Of Blood Pressure Phenotypes In The Trans-omics For Precision Medicine And Centers For Common Disease Genomics Programs Circulation. 141. DOI: 10.1161/Circ.141.Suppl_1.46  0.396
2019 Irvin MR, Sitlani CM, Floyd JS, Psaty BM, Bis JC, Wiggins KL, Whitsel EA, Sturmer T, Stewart J, Raffield L, Sun F, Liu CT, Xu H, Cupples AL, Tanner RM, ... ... Hellwege JN, et al. Genome wide association study of apparent treatment resistant hypertension in the CHARGE consortium: The CHARGE Pharmacogenetics Working Group. American Journal of Hypertension. PMID 31545351 DOI: 10.1093/Ajh/Hpz150  0.336
2019 Hellwege JN, Velez Edwards DR, Giri A, Qiu C, Park J, Torstenson ES, Keaton JM, Wilson OD, Robinson-Cohen C, Chung CP, Roumie CL, Klarin D, Damrauer SM, DuVall SL, Siew E, et al. Mapping eGFR loci to the renal transcriptome and phenome in the VA Million Veteran Program. Nature Communications. 10: 3842. PMID 31451708 DOI: 10.1038/S41467-019-11704-W  0.367
2019 Edwards TL, Giri A, Hellwege JN, Hartmann KE, Stewart EA, Jeff JM, Bray MJ, Pendergrass SA, Torstenson ES, Keaton JM, Jones SH, Gogoi RP, Kuivaniemi H, Jackson KL, Kho AN, et al. A -Ethnic Genome-Wide Association Study of Uterine Fibroids. Frontiers in Genetics. 10: 511. PMID 31249589 DOI: 10.3389/Fgene.2019.00511  0.528
2019 Hellwege JN, Stallings S, Torstenson ES, Carroll R, Borthwick KM, Brilliant MH, Crosslin D, Gordon A, Hripcsak G, Jarvik GP, Linneman JG, Devi P, Peissig PL, Sleiman PAM, Hakonarson H, et al. Heritability and genome-wide association study of benign prostatic hyperplasia (BPH) in the eMERGE network. Scientific Reports. 9: 6077. PMID 30988330 DOI: 10.1038/S41598-019-42427-Z  0.456
2019 Giri A, Hellwege JN, Keaton JM, Park J, Qiu C, Warren HR, Torstenson ES, Kovesdy CP, Sun YV, Wilson OD, Robinson-Cohen C, Roumie CL, Chung CP, Birdwell KA, Damrauer SM, et al. Trans-ethnic association study of blood pressure determinants in over 750,000 individuals. Nature Genetics. 51: 51-62. PMID 30578418 DOI: 10.1038/S41588-018-0303-9  0.374
2018 Evangelou E, Warren HR, Mosen-Ansorena D, Mifsud B, Pazoki R, Gao H, Ntritsos G, Dimou N, Cabrera CP, Karaman I, Ng FL, Evangelou M, Witkowska K, Tzanis E, Hellwege JN, et al. Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits. Nature Genetics. PMID 30429575 DOI: 10.1038/S41588-018-0297-3  0.351
2018 Wang H, Nandakumar P, Tekola-Ayele F, Tayo BO, Ware EB, Gu CC, Lu Y, Yao J, Zhao W, Smith JA, Hellwege JN, Guo X, Edwards TL, Loos RJF, Arnett DK, et al. Combined linkage and association analysis identifies rare and low frequency variants for blood pressure at 1q31. European Journal of Human Genetics : Ejhg. PMID 30262922 DOI: 10.1038/S41431-018-0277-1  0.537
2018 Evangelou E, Warren HR, Mosen-Ansorena D, Mifsud B, Pazoki R, Gao H, Ntritsos G, Dimou N, Cabrera CP, Karaman I, Ng FL, Evangelou M, Witkowska K, Tzanis E, Hellwege JN, et al. Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits. Nature Genetics. PMID 30224653 DOI: 10.1038/S41588-018-0205-X  0.328
2018 Keaton JM, Gao C, Guan M, Hellwege JN, Palmer ND, Pankow JS, Fornage M, Wilson JG, Correa A, Rasmussen-Torvik LJ, Rotter JI, Chen YI, Taylor KD, Rich SS, Wagenknecht LE, et al. Genome-wide interaction with the insulin secretion locus MTNR1B reveals CMIP as a novel type 2 diabetes susceptibility gene in African Americans. Genetic Epidemiology. PMID 29691896 DOI: 10.1002/Gepi.22126  0.601
2018 Weigl K, Thomsen H, Balavarca Y, Hellwege JN, Shrubsole MJ, Brenner H. Genetic Risk Score is Associated With Prevalence of Advanced Neoplasms in a Colorectal Cancer Screening Population. Gastroenterology. PMID 29574091 DOI: 10.1053/J.Gastro.2018.03.030  0.378
2018 Hellwege JN, Russell SB, Williams SM, Edwards TL, Velez Edwards DR. Gene-based evaluation of low-frequency variation and genetically-predicted gene expression impacting risk of keloid formation. Annals of Human Genetics. PMID 29484647 DOI: 10.1111/Ahg.12245  0.436
2018 Warren H, Evangelou E, Mosen D, Mifsud B, Pazoki R, Gao H, Ntritsos G, Dimou N, Evangelou M, Hellwege J, Giri A, Esko T, Metspalu A, Tzoulaki I, Barnes M, et al. GENETIC ANALYSIS OF OVER ONE MILLION PEOPLE IDENTIFIES 535 NOVEL LOCI ASSOCIATED WITH BLOOD PRESSURE AND RISK OF CARDIOVASCULAR DISEASE Journal of Hypertension. 36: e229. DOI: 10.1097/01.Hjh.0000539644.13726.3B  0.373
2017 Gao C, Langefeld CD, Ziegler JT, Taylor KD, Norris JM, Chen YI, Hellwege JN, Guo X, Allison MA, Speliotes EK, Rotter JI, Bowden DW, Wagenknecht LE, Palmer ND. Genome-Wide Study of Subcutaneous and Visceral Adipose Tissue Reveals Novel Sex-Specific Adiposity Loci in Mexican Americans. Obesity (Silver Spring, Md.). PMID 29178545 DOI: 10.1002/Oby.22074  0.524
2017 Hellwege JN, Keaton JM, Giri A, Gao X, Velez Edwards DR, Edwards TL. Population Stratification in Genetic Association Studies. Current Protocols in Human Genetics. 95: 1.22.1-1.22.23. PMID 29044472 DOI: 10.1002/Cphg.48  0.373
2017 Hellwege JN, Jeff JM, Wise LA, Gallagher CS, Wellons M, Hartmann KE, Jones SF, Torstenson ES, Dickinson S, Ruiz-Narváez EA, Rohland N, Allen A, Reich D, Tandon A, Pasaniuc B, et al. Erratum to: A multi-stage genome-wide association study of uterine fibroids in African Americans. Human Genetics. PMID 28975356 DOI: 10.1007/S00439-017-1846-Z  0.327
2017 Hellwege JN, Jeff JM, Wise LA, Gallagher CS, Wellons M, Hartmann KE, Jones SF, Torstenson ES, Dickinson S, Ruiz-Narváez EA, Rohland N, Allen A, Reich D, Tandon A, Pasaniuc B, et al. A multi-stage genome-wide association study of uterine fibroids in African Americans. Human Genetics. PMID 28836065 DOI: 10.1007/S00439-017-1836-1  0.44
2017 Hellwege JN, Torstenson ES, Russell SB, Edwards TL, Velez Edwards DR. Evidence of selection as a cause for racial disparities in fibroproliferative disease. Plos One. 12: e0182791. PMID 28792542 DOI: 10.1371/Journal.Pone.0182791  0.413
2017 Tabb KL, Hellwege JN, Palmer ND, Dimitrov L, Sajuthi S, Taylor KD, Ng MC, Hawkins GA, Chen YI, Brown WM, McWilliams D, Williams A, Lorenzo C, Norris JM, Long J, et al. Analysis of Whole Exome Sequencing with Cardiometabolic Traits Using Family-Based Linkage and Association in the IRAS Family Study. Annals of Human Genetics. PMID 28067407 DOI: 10.1111/Ahg.12184  0.632
2016 Keaton JM, Hellwege JN, Ng MC, Palmer ND, Pankow JS, Fornage M, Wilson JG, Correa A, Rasmussen-Torvik LJ, Rotter JI, Chen YI, Taylor KD, Rich SS, Wagenknecht LE, Freedman BI, et al. GENOME-WIDE INTERACTION WITH SELECTED TYPE 2 DIABETES LOCI REVEALS NOVEL LOCI FOR TYPE 2 DIABETES IN AFRICAN AMERICANS. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 22: 242-253. PMID 27896979 DOI: 10.1142/9789813207813_0024  0.588
2016 Hellwege JN, Palmer ND, Dimitrov L, Keaton JM, Tabb KL, Sajuthi S, Taylor KD, Ng MC, Speliotes EK, Hawkins GA, Long J, Ida Chen YD, Lorenzo C, Norris JM, Rotter JI, et al. Genome-wide linkage and association analysis of cardiometabolic phenotypes in Hispanic Americans. Journal of Human Genetics. PMID 27535031 DOI: 10.1038/Jhg.2016.103  0.665
2016 Keaton JM, Hellwege JN, Ng MC, Palmer ND, Pankow JS, Fornage M, Wilson JG, Correa A, Rasmussen-Torvik LJ, Rotter JI, Chen YI, Taylor KD, Rich SS, Wagenknecht LE, Freedman BI, et al. Genome-Wide Interaction with Insulin Secretion Loci Reveals Novel Loci for Type 2 Diabetes in African Americans. Plos One. 11: e0159977. PMID 27448167 DOI: 10.1371/Journal.Pone.0159977  0.602
2015 Hellwege JN, Palmer ND, Mark Brown W, Brown MW, Ziegler JT, Sandy An S, An SS, Guo X, Ida Chen YD, Chen IY, Taylor K, Hawkins GA, Ng MC, Speliotes EK, Lorenzo C, et al. Empirical characteristics of family-based linkage to a complex trait: the ADIPOQ region and adiponectin levels. Human Genetics. 134: 203-13. PMID 25447270 DOI: 10.1007/S00439-014-1511-8  0.687
2014 Hellwege JN, Palmer ND, Raffield LM, Ng MC, Hawkins GA, Long J, Lorenzo C, Norris JM, Ida Chen YD, Speliotes EK, Rotter JI, Langefeld CD, Wagenknecht LE, Bowden DW. Genome-wide family-based linkage analysis of exome chip variants and cardiometabolic risk. Genetic Epidemiology. 38: 345-52. PMID 24719370 DOI: 10.1002/Gepi.21801  0.654
2014 Hellwege JN, Palmer ND, Ziegler JT, Langefeld CD, Lorenzo C, Norris JM, Takamura T, Bowden DW. Genetic variants in selenoprotein P plasma 1 gene (SEPP1) are associated with fasting insulin and first phase insulin response in Hispanics. Gene. 534: 33-9. PMID 24161883 DOI: 10.1016/J.Gene.2013.10.035  0.588
2014 Hellwege JN, Palmer ND, Brown WM, Ziegler JT, An SS, Guo X, Chen YI, Taylor K, Hawkins GA, Ng MCY, Speliotes EK, Lorenzo C, Norris JM, Rotter JI, Wagenknecht LE, et al. Erratum to: Empirical characteristics of family-based linkage to a complex trait: the ADIPOQ region and adiponectin levels Human Genetics. 134: 215-215. DOI: 10.1007/S00439-014-1518-1  0.49
2012 Cooke JN, Bostrom MA, Hicks PJ, Ng MC, Hellwege JN, Comeau ME, Divers J, Langefeld CD, Freedman BI, Bowden DW. Polymorphisms in MYH9 are associated with diabetic nephropathy in European Americans. Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. 27: 1505-11. PMID 21968013 DOI: 10.1093/Ndt/Gfr522  0.595
2011 Hellwege JN, Hicks PJ, Palmer ND, Ng MC, Freedman BI, Bowden DW. Examination of Rare Variants in HNF4 α in European Americans with Type 2 Diabetes. Journal of Diabetes & Metabolism. 2. PMID 23227446 DOI: 10.4172/2155-6156.1000145  0.575
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