| Year |
Citation |
Score |
| 2023 |
Wang K, Marciani L, Amidon GL, Smith DE, Sun D. Stochastic Differential Equation-based Mixed Effects Model of the Fluid Volume in the Fasted Stomach in Healthy Adult Human. The Aaps Journal. 25: 76. PMID 37498389 DOI: 10.1208/s12248-023-00840-3 |
0.407 |
|
| 2022 |
Wang K, Li Y, Chen B, Chen H, Smith DE, Sun D, Feng MR, Amidon GL. In Vitro Predictive Dissolution Test Should Be Developed and Recommended as a Bioequivalence Standard for the Immediate-Release Solid Oral Dosage Forms of the Highly Variable Mycophenolate Mofetil. Molecular Pharmaceutics. PMID 35603895 DOI: 10.1021/acs.molpharmaceut.1c00792 |
0.442 |
|
| 2020 |
Huddle BC, Grimley E, Chtcherbinine M, Buchman CD, Takahashi C, Debnath B, McGonigal SC, Mao S, Li S, Felton J, Pan S, Wen B, Sun D, Neamati N, Buckanovich RJ, et al. Development of 2,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one inhibitors of aldehyde dehydrogenase 1A (ALDH1A) as potential adjuncts to ovarian cancer chemotherapy. European Journal of Medicinal Chemistry. 211: 113060. PMID 33341649 DOI: 10.1016/j.ejmech.2020.113060 |
0.539 |
|
| 2020 |
Hu S, Sechi M, Singh PK, Dai L, McCann S, Sun D, Ljungman M, Neamati N. A Novel Redox Modulator Induces a GPX4-mediated Cell Death That Is Dependent on Iron and Reactive Oxygen Species. Journal of Medicinal Chemistry. PMID 32809827 DOI: 10.1021/Acs.Jmedchem.0C01016 |
0.352 |
|
| 2020 |
Bailey CM, Liu Y, Peng G, Zhang H, He M, Sun D, Zheng P, Liu Y, Wang Y. Liposomal formulation of HIF-1α inhibitor Echinomycin eliminates established metastases of triple-negative breast Cancer. Nanomedicine : Nanotechnology, Biology, and Medicine. 102278. PMID 32738299 DOI: 10.1016/J.Nano.2020.102278 |
0.327 |
|
| 2020 |
Rej RK, Wang C, Lu J, Wang M, Petrunak E, Zawacki KP, McEachern D, Fernandez-Salas E, Yang CY, Wang L, Li R, Chinnaswamy K, Wen B, Sun D, Stuckey J, et al. EEDi-5285: An Exceptionally Potent, Efficacious, and Orally Active Small-Molecule Inhibitor of Embryonic Ectoderm Development. Journal of Medicinal Chemistry. PMID 32580550 DOI: 10.1021/Acs.Jmedchem.0C00479 |
0.344 |
|
| 2020 |
Yuan H, Guo H, Luan X, He M, Li F, Burnett J, Truchan N, Sun D. Albumin Nanoparticle of Paclitaxel (Abraxane) Decreases while Taxol Increases Breast Cancer Stem Cells in Treatment of Triple Negative Breast Cancer. Molecular Pharmaceutics. PMID 32485107 DOI: 10.1021/Acs.Molpharmaceut.9B01221 |
0.387 |
|
| 2020 |
Gasparyan M, Lo MC, Jiang H, Lin CC, Sun D. Combined P53/PTEN deficiency activates expression of mesenchyme homeobox 1 (MEOX1) required for growth of triple-negative breast cancer. The Journal of Biological Chemistry. PMID 32467227 DOI: 10.1074/Jbc.Ra119.010710 |
0.353 |
|
| 2020 |
Lin CC, Lo MC, Moody R, Jiang H, Harouaka R, Stevers N, Tinsley S, Gasparyan M, Wicha M, Sun D. Corrigendum to "Targeting LRP8 inhibits breast cancer stem cells in triple-negative breast cancer" [Canc. Lett. 438 (2018, Dec 1) 165-173]. Cancer Letters. PMID 32229161 DOI: 10.1016/J.Canlet.2020.01.013 |
0.341 |
|
| 2020 |
Tan YS, Heath BR, Hill BD, Luo X, Rizvi SM, Moghbeli T, Hu H, Siismets E, Wen H, Xie Y, Sun D, Young S, Zou W, Wen F, Lei YL. Abstract A08: Resolving STING-mediated tumor immune microenvironment shift at single-cell resolution Clinical Cancer Research. 26. DOI: 10.1158/1557-3265.Aacrahns19-A08 |
0.327 |
|
| 2020 |
Burnett JP, Johnson G, Truchan N, Brooks M, Wicha MS, Sun D. Abstract 500: Discovering epigenetic regulators of cells states in triple negative breast cancers Cancer Research. 80: 500-500. DOI: 10.1158/1538-7445.Am2020-500 |
0.372 |
|
| 2019 |
Wang Y, Zhao L, Han X, Wang Y, Mi J, Wang C, Sun D, Fu Y, Zhao X, Guo H, Wang Q. Saikosaponin A Inhibits Triple-Negative Breast Cancer Growth and Metastasis Through Downregulation of CXCR4. Frontiers in Oncology. 9: 1487. PMID 32047724 DOI: 10.3389/Fonc.2019.01487 |
0.365 |
|
| 2019 |
Zhou H, Bai L, Xu R, Zhao Y, Chen J, McEachern D, Chinnaswamy K, Wen B, Dai L, Kumar P, Yang CY, Liu Z, Wang M, Liu L, Meagher JL, ... ... Sun D, et al. Structure-Based Discovery of SD-36 as a Potent, Selective and Efficacious PROTAC Degrader of STAT3 Protein. Journal of Medicinal Chemistry. PMID 31747516 DOI: 10.1021/Acs.Jmedchem.9B01530 |
0.345 |
|
| 2019 |
Bai L, Zhou H, Xu R, Zhao Y, Chinnaswamy K, McEachern D, Chen J, Yang CY, Liu Z, Wang M, Liu L, Jiang H, Wen B, Kumar P, Meagher JL, ... Sun D, et al. A Potent and Selective Small-Molecule Degrader of STAT3 Achieves Complete Tumor Regression In Vivo. Cancer Cell. 36: 498-511.e17. PMID 31715132 DOI: 10.1016/J.Ccell.2019.10.002 |
0.363 |
|
| 2019 |
Yu A, Koenigsknecht MJ, Hens B, Baker JR, Wen B, Jackson TL, Pai MP, Hasler W, Amidon GL, Sun D. Mechanistic Deconvolution of Oral Absorption Model with Dynamic Gastrointestinal Fluid to Predict Regional Rate and Extent of GI Drug Dissolution. The Aaps Journal. 22: 3. PMID 31712917 DOI: 10.1208/S12248-019-0385-Z |
0.522 |
|
| 2019 |
Kahl D, Hutchings KM, Lisabeth EM, Haak A, Leipprandt JR, Dexheimer TS, Khanna D, Tsou PS, Campbell PL, Fox DA, Wen B, Sun D, Bailie M, Neubig RR, Larsen SD. 5-Aryl-1,3,4-oxadiazol-2-ylthioalkanoic Acids: A Highly Potent New Class of Inhibitors of Rho/Myocardin-Related Transcription Factor (MRTF)/Serum Reponse Factor (SRF)-Mediated Gene Transcription as Potential Antifibrotic Agents for Scleroderma. Journal of Medicinal Chemistry. PMID 30951312 DOI: 10.1021/Acs.Jmedchem.8B01772 |
0.316 |
|
| 2019 |
Sun L, Yuan H, Burnett J, Gasparyan M, Zhang Y, Zhang F, Yang Z, Ran Y, Sun D. MEOX1 Promotes Tumor Progression and Predicts Poor Prognosis in Human Non-Small-Cell Lung Cancer. International Journal of Medical Sciences. 16: 68-74. PMID 30662330 DOI: 10.7150/Ijms.27595 |
0.332 |
|
| 2019 |
Baker JR, Dickens JR, Koenigsknecht M, Frances A, Lee AA, Shedden KA, Brasseur JG, Amidon GL, Sun D, Hasler WL. Propagation Characteristics of Fasting Duodeno-Jejunal Contractions in Healthy Controls Measured by Clustered Closely-spaced Manometric Sensors. Journal of Neurogastroenterology and Motility. 25: 100-112. PMID 30646481 DOI: 10.5056/Jnm18112 |
0.423 |
|
| 2019 |
Chen H, Luan X, Paholak H, Burnett J, Stevers N, Sansanaphongpricha K, He M, Chang A, Li Q, Sun D. Abstract 3220: Enhancing breast cancer immunotherapy via IONP-mediated photothermal therapy Immunology. DOI: 10.1158/1538-7445.Sabcs18-3220 |
0.311 |
|
| 2019 |
Truchan NA, Burnett JP, Sun D. Abstract 968: Targeting intratumoral heterogeneity in TNBC with novel combinations of FDA-approved drugs Cancer Research. 79: 968-968. DOI: 10.1158/1538-7445.Am2019-968 |
0.388 |
|
| 2018 |
Paixão P, Bermejo M, Hens B, Tsume Y, Dickens J, Shedden K, Salehi N, Koenigsknecht MJ, Baker JR, Hasler WL, Lionberger R, Fan J, Wysocki J, Wen B, Lee A, ... ... Sun D, et al. Linking the Gastrointestinal Behavior of Ibuprofen with the Systemic Exposure between and within Humans-Part 2: Fed State. Molecular Pharmaceutics. PMID 30417648 DOI: 10.1021/Acs.Molpharmaceut.8B00736 |
0.711 |
|
| 2018 |
Bermejo M, Paixão P, Hens B, Tsume Y, Koenigsknecht MJ, Baker JR, Hasler WL, Lionberger R, Fan J, Dickens J, Shedden KA, Wen B, Wysocki J, Löbenberg R, Lee A, ... ... Sun D, et al. Linking the Gastrointestinal Behavior of Ibuprofen with The Systemic Exposure Between and Within Humans - Part 1: Fasted State. Molecular Pharmaceutics. PMID 30372084 DOI: 10.1021/Acs.Molpharmaceut.8B00515 |
0.708 |
|
| 2018 |
Lin CC, Lo MC, Moody R, Jiang H, Harouaka R, Stevers N, Tinsley S, Gasparyan M, Wicha M, Sun D. Targeting LRP8 inhibits breast cancer stem cells in triple-negative breast cancer. Cancer Letters. PMID 30227220 DOI: 10.1016/J.Canlet.2018.09.022 |
0.366 |
|
| 2018 |
Huddle BC, Grimley E, Buchman CD, Chtcherbinine M, Debnath B, Mehta P, Yang K, Morgan CA, Li S, Felton JA, Sun D, Metha G, Neamati N, Buckanovich RJ, Hurley TD, et al. Structure-Based Optimization of a Novel Class of Aldehyde Dehydrogenase 1A (ALDH1A) Subfamily-Selective Inhibitors as Potential Adjuncts to Ovarian Cancer Chemotherapy. Journal of Medicinal Chemistry. PMID 30221940 DOI: 10.1021/Acs.Jmedchem.8B00930 |
0.59 |
|
| 2018 |
Tsume Y, Patel S, Fotaki N, Bergstrӧm C, Amidon GL, Brasseur JG, Mudie DM, Sun D, Bermejo M, Gao P, Zhu W, Sperry DC, Vertzoni M, Parrott N, Lionberger R, et al. In Vivo Predictive Dissolution and Simulation Workshop Report: Facilitating the Development of Oral Drug Formulation and the Prediction of Oral Bioperformance. The Aaps Journal. 20: 100. PMID 30191341 DOI: 10.1208/S12248-018-0260-3 |
0.699 |
|
| 2018 |
Li F, Zhang H, He M, Liao J, Chen N, Li Y, Zhou S, Palmisano M, Yu A, Pai MP, Yuan H, Sun D. Different nanoformulations alter the tissue distribution of paclitaxel, which aligns with reported distinct efficacy and safety profiles. Molecular Pharmaceutics. PMID 30180593 DOI: 10.1021/Acs.Molpharmaceut.8B00527 |
0.306 |
|
| 2018 |
Qin C, Hu Y, Zhou B, Fernandez-Salas E, Yang CY, Liu L, McEachern D, Przybranowski S, Wang M, Stuckey J, Meagher J, Bai L, Chen Z, Lin M, Yang J, ... ... Sun D, et al. Discovery of QCA570 as an Exceptionally Potent and Efficacious Proteolysis Targeting Chimera (PROTAC) Degrader of the Bromodomain and Extra-Terminal (BET) Proteins Capable of Inducing Complete and Durable Tumor Regression. Journal of Medicinal Chemistry. PMID 30019901 DOI: 10.1021/Acs.Jmedchem.8B00506 |
0.584 |
|
| 2018 |
Zhao Y, Zhou B, Bai L, Liu L, Yang CY, Meagher JL, Stuckey JA, McEachern D, Przybranowski S, Wang M, Ran X, Aguilar A, Hu Y, Kampf JW, Li X, ... ... Sun D, et al. Structure-Based Discovery of CF53 as a Potent and Orally Bioavailable Bromodomain and Extra-Terminal (BET) Bromodomain Inhibitor. Journal of Medicinal Chemistry. PMID 30015487 DOI: 10.1021/Acs.Jmedchem.8B00483 |
0.582 |
|
| 2018 |
Hens B, Sinko P, Job N, Dean M, Al-Gousous J, Salehi N, Ziff RM, Tsume Y, Bermejo M, Paixão P, Brasseur JG, Yu A, Talattof A, Benninghoff G, Langguth P, ... ... Sun D, et al. Formulation Predictive Dissolution (fPD) Testing to Advance Oral Drug Product Development: an Introduction to the US FDA Funded '21 Century BA/BE' Project. International Journal of Pharmaceutics. PMID 29944899 DOI: 10.1016/J.Ijpharm.2018.06.050 |
0.763 |
|
| 2018 |
Paixão P, Bermejo M, Hens B, Tsume Y, Dickens J, Shedden K, Salehi N, Koenigsknecht MJ, Baker JR, Hasler WL, Lionberger R, Fan J, Wysocki J, Wen B, Lee A, ... ... Sun D, et al. Gastric Emptying and Intestinal Appearance of Nonabsorbable Drugs Phenol Red and Paromomycin in Human Subjects: A Multi-Compartment Stomach Approach. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. PMID 29857136 DOI: 10.1016/J.Ejpb.2018.05.033 |
0.704 |
|
| 2018 |
Li W, Tanikawa T, Kryczek I, Xia H, Li G, Wu K, Wei S, Zhao L, Vatan L, Wen B, Shu P, Sun D, Kleer C, Wicha M, Sabel M, et al. Aerobic Glycolysis Controls Myeloid-Derived Suppressor Cells and Tumor Immunity via a Specific CEBPB Isoform in Triple-Negative Breast Cancer. Cell Metabolism. PMID 29805099 DOI: 10.1016/J.Cmet.2018.04.022 |
0.349 |
|
| 2018 |
Borkin D, Klossowski S, Pollock J, Miao H, Linhares B, Kempinska K, Jin Z, Purohit T, Wen B, He M, Sun D, Cierpicki T, Grembecka J. The complexity of blocking bivalent protein-protein interactions: development of a highly potent inhibitor of the menin-Mixed Lineage Leukemia (MLL) interaction. Journal of Medicinal Chemistry. PMID 29738674 DOI: 10.1021/Acs.Jmedchem.8B00071 |
0.314 |
|
| 2018 |
Lin CC, Lo MC, Moody RR, Stevers NO, Tinsley SL, Sun D. Doxycycline targets aldehyde dehydrogenase‑positive breast cancer stem cells. Oncology Reports. PMID 29620216 DOI: 10.3892/Or.2018.6337 |
0.411 |
|
| 2018 |
Hens B, Al-Gousous J, Wang K, Salehi N, Ziff RM, Tsume Y, Bermejo M, Paixão P, Brasseur JG, Yu A, Talattof A, Benninghoff G, Langguth P, Lennernäs H, Hasler WL, ... ... Sun D, et al. Summary of the In Vivo Predictive Dissolution (iPD) - Oral Drug Delivery (ODD) Conference 2018 Dissolution Technologies. 25: 50-53. DOI: 10.14227/Dt250218P50 |
0.708 |
|
| 2018 |
Luo M, Brooks M, Burnett J, Truchan N, Sun D, Wicha MS. Abstract LB-053: Tracing redox-regulated breast cancer stem cell state transition using a dual fluorescent reporter system Cancer Research. 78. DOI: 10.1158/1538-7445.Am2018-Lb-053 |
0.339 |
|
| 2018 |
Truchan NA, Buschhaus J, Brooks M, Halabu A, Guo H, Yuan H, Luker K, Wicha M, Sun D, Burnett JP. Abstract 2007: A novel CRISPR/Cas9 reporter system to monitor TNBC cancer stem cells in real time Cancer Research. 78: 2007-2007. DOI: 10.1158/1538-7445.Am2018-2007 |
0.402 |
|
| 2018 |
Lin C, Lo M, Moody R, Stevers N, Tinsley S, Gasparyan M, Wicha M, Sun D. Abstract 2004: Identification of MLK4 as a novel regulator of cancer stem cells in triple-negative breast cancer Tumor Biology. DOI: 10.1158/1538-7445.Am2018-2004 |
0.352 |
|
| 2018 |
Kump KJ, Tong J, Mady AS, Miao L, Li S, Sun D, Yu J, Zhang L, Nikolovska-Coleska Z. Abstract 1970: Novel Mcl-1 inhibitor effectively restores in vivo regorafenib sensitivity in resistant colorectal cancer Cancer Research. 78: 1970-1970. DOI: 10.1158/1538-7445.Am2018-1970 |
0.377 |
|
| 2018 |
Hasler WL, Baker J, Dickens J, Koenigsknecht M, Frances A, Lee A, Shedden K, Harer K, Amidon G, Sun D. Sa1561 - Standardizing Parameters of Fasting Duodenojejunal Manometry in Healthy Volunteers Using Clustered High-Resolution Pressure Ports: Focus on Migrating Motor Complex Phase 2 Contractions Gastroenterology. 154: S-311. DOI: 10.1016/S0016-5085(18)31385-4 |
0.415 |
|
| 2017 |
Moody RR, Lo MC, Meagher JL, Lin CC, Stevers NO, Tinsley SL, Jung I, Matvekas A, Stuckey JA, Sun D. Probing the interaction between the histone methyltransferase/deacetylase subunit RBBP4/7 and the transcription factor BCL11A in epigenetic complexes. The Journal of Biological Chemistry. PMID 29263092 DOI: 10.1074/Jbc.M117.811463 |
0.301 |
|
| 2017 |
Conner TM, Nikolian VC, Georgoff PE, Pai MP, Alam HB, Sun D, Reed RC, Zhang T. Physiologically based pharmacokinetic modeling of disposition and drug-drug interactions for valproic acid and divalproex. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. PMID 29030176 DOI: 10.1016/J.Ejps.2017.10.009 |
0.327 |
|
| 2017 |
Yu A, Jackson T, Tsume Y, Koenigsknecht M, Wysocki J, Marciani L, Amidon GL, Frances A, Baker JR, Hasler W, Wen B, Pai A, Sun D. Mechanistic Fluid Transport Model to Estimate Gastrointestinal Fluid Volume and Its Dynamic Change Over Time. The Aaps Journal. PMID 28980204 DOI: 10.1208/S12248-017-0145-X |
0.694 |
|
| 2017 |
Sun D, Baker JR, Wen B, Frances A, Zhang H, Yu A, Zhao T, Tsume Y, Pai M, Bleske B, Zhang X, Lionberger R, Lee A, Amidon G, Hasler WL, et al. In Vivo Dissolution and Systemic Absorption of Immediate Release Ibuprofen in Human Gastrointestinal Tract Under Fed and Fasted Conditions. Molecular Pharmaceutics. PMID 28937221 DOI: 10.1021/Acs.Molpharmaceut.7B00425 |
0.719 |
|
| 2017 |
Hens B, Tsume Y, Bermejo M, Paixao P, Koenigsknecht M, Baker JR, Hasler WL, Lionberger R, Fan J, Dickens J, Shedden KA, Wen B, Wysocki J, Löbenberg R, Lee A, ... ... Sun D, et al. Low Buffer Capacity and Alternating Motility Along The Human Gastrointestinal Tract: Implications for In Vivo Dissolution and Absorption of Ionizable Drugs. Molecular Pharmaceutics. PMID 28737409 DOI: 10.1021/Acs.Molpharmaceut.7B00426 |
0.709 |
|
| 2017 |
Zhao Y, Bai L, Liu L, McEachern D, Stuckey JA, Meagher JL, Yang CY, Ran X, Zhou B, Hu Y, Li X, Wen B, Zhao T, Li S, Sun D, et al. Structure-Based Discovery of 4-(6-Methoxy-2-methyl-4-(quinolin-4-yl)-9H-pyrimido[4,5-b]indol-7-yl)-3,5-dimethylisoxazole (CD161) as a Potent and Orally Bioavailable BET Bromodomain Inhibitor. Journal of Medicinal Chemistry. PMID 28463487 DOI: 10.1021/Acs.Jmedchem.7B00193 |
0.572 |
|
| 2017 |
Wang M, Xie F, Wen X, Chen H, Zhang H, Liu J, Zhang H, Zou H, Yu Y, Chen Y, Sun Z, Wang X, Zhang G, Yin C, Sun D, et al. Therapeutic PEG-ceramide nanomicelles synergize with salinomycin to target both liver cancer cells and cancer stem cells. Nanomedicine (London, England). PMID 28440698 DOI: 10.2217/Nnm-2016-0408 |
0.529 |
|
| 2017 |
Aguilar A, Lu J, Liu L, Du D, Bernard D, McEachern D, Przybranowski S, Li X, Luo R, Wen B, Sun D, Wang H, Wen J, Wang G, Zhai Y, et al. Discovery of 4-((3'R,4'S,5'R)-6″-Chloro-4'-(3-chloro-2-fluorophenyl)-1'-ethyl-2″-oxodispiro[cyclohexane-1,2'-pyrrolidine-3',3″-indoline]-5'-carboxamido)bicyclo[2.2.2]octane-1-carboxylic Acid (AA-115/APG-115): A Potent and Orally Active Murine Double Minute 2 (MDM2) Inhibitor in Clinical Development. Journal of Medicinal Chemistry. PMID 28339198 DOI: 10.1021/Acs.Jmedchem.6B01665 |
0.318 |
|
| 2017 |
Zhou B, Hu J, Xu F, Chen Z, Bai L, Fernandez-Salas E, Lin M, Liu L, Yang CY, Zhao Y, McEachern D, Przybranowski S, Wen B, Sun D, Wang S. Discovery of a Small-Molecule Degrader of Bromodomain and Extra-Terminal (BET) Proteins with Picomolar Cellular Potencies and Capable of Achieving Tumor Regression. Journal of Medicinal Chemistry. PMID 28339196 DOI: 10.1021/Acs.Jmedchem.6B01816 |
0.338 |
|
| 2017 |
Hutchings KM, Lisabeth EM, Rajeswaran W, Wilson MW, Sorenson RJ, Campbell PL, Ruth JH, Amin A, Tsou PS, Leipprandt JR, Olson SR, Wen B, Zhao T, Sun D, Khanna D, et al. Pharmacokinetic optimitzation of CCG-203971: Novel inhibitors of the Rho/MRTF/SRF transcriptional pathway as potential antifibrotic therapeutics for systemic scleroderma. Bioorganic & Medicinal Chemistry Letters. PMID 28285914 DOI: 10.1016/J.Bmcl.2017.02.070 |
0.321 |
|
| 2017 |
Tsume Y, Matsui K, Searls AL, Takeuchi S, Amidon GE, Sun D, Amidon GL. The impact of supersaturation level for oral absorption of BCS class IIb drugs, dipyridamole and ketoconazole, using in vivo predictive dissolution system: Gastrointestinal Simulator (GIS). European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. PMID 28263914 DOI: 10.1016/J.Ejps.2017.02.042 |
0.726 |
|
| 2017 |
Burnett JP, Lim G, Li Y, Shah RB, Lim R, Paholak HJ, McDermott SP, Sun L, Tsume Y, Bai S, Wicha MS, Sun D, Zhang T. Sulforaphane Enhances the Anticancer Activity of Taxanes against Triple Negative Breast Cancer by Killing Cancer Stem Cells. Cancer Letters. PMID 28254410 DOI: 10.1016/J.Canlet.2017.02.023 |
0.683 |
|
| 2017 |
Bai L, Zhou B, Yang CY, Ji J, McEachern D, Przybranowski S, Jiang H, Hu J, Xu F, Zhao Y, Liu L, Fernandez-Salas E, Xu J, Dou Y, Wen B, ... Sun D, et al. Targeted degradation of BET proteins in triple-negative breast cancer. Cancer Research. PMID 28209615 DOI: 10.1158/0008-5472.Can-16-2622 |
0.394 |
|
| 2017 |
Guo H, Luo H, Yuan H, Xia Y, Shu P, Huang X, Lu Y, Liu X, Keller ET, Sun D, Deng J, Zhang J. Litchi seed extracts diminish prostate cancer progression via induction of apoptosis and attenuation of EMT through Akt/GSK-3β signaling. Scientific Reports. 7: 41656. PMID 28134352 DOI: 10.1038/Srep41656 |
0.319 |
|
| 2017 |
Sun L, Guo C, Burnett J, Pan J, Yang Z, Ran Y, Sun D. Association between expression of Carboxypeptidase 4 and stem cell markers and their clinical significance in liver cancer development. Journal of Cancer. 8: 111-116. PMID 28123604 DOI: 10.7150/Jca.17060 |
0.311 |
|
| 2017 |
Burnett JP, Fouladdel S, Truchan N, Azizi E, Wicha M, Sun D. Abstract 940: Altering intratumoral heterogeneity in HER2+ breast cancers with PTEN inactivation and trastuzumab therapy Cancer Research. 77: 940-940. DOI: 10.1158/1538-7445.Am2017-940 |
0.307 |
|
| 2017 |
Mahran R, Shu P, Sun D, Brenner DE. Abstract 5257: Cellular pharmacology of curcumin cellular pharmacology of curcumin±piperine Cancer Research. 77: 5257-5257. DOI: 10.1158/1538-7445.Am2017-5257 |
0.321 |
|
| 2017 |
Wu T, Kessler L, Li S, Purohit T, Li S, Miao H, Linhares B, Hansen R, Kucharski J, Wang Y, Yu K, Kempinska K, Ely T, Klossowski S, Zarieh A, ... ... Sun D, et al. Abstract 5077: A novel small molecule menin-MLL inhibitor for potential treatment of MLL-rearranged leukemias Cancer Research. 77: 5077-5077. DOI: 10.1158/1538-7445.Am2017-5077 |
0.378 |
|
| 2017 |
Yuan H, Guo H, Li F, Burnett J, He M, Truchan N, Myers I, Sun D. Abstract 4788: Abraxane eliminates cancer stem cells in triple-negative breast cancers Cancer Research. 77: 4788-4788. DOI: 10.1158/1538-7445.Am2017-4788 |
0.393 |
|
| 2017 |
Lin C, Lo M, Moody R, Stevers N, Tinsley S, Wicha M, Sun D. Abstract 4767: Identifying CDCA7 as a novel regulator of tumor-initiating cells in triple-negative breast cancer Cancer Research. 77: 4767-4767. DOI: 10.1158/1538-7445.Am2017-4767 |
0.346 |
|
| 2017 |
Stevers NO, Tinsley SL, Moody R, Lin C, Meagher J, Stuckey JA, Lo M, Sun D. Abstract 4495: Elucidating BCL11A’s function in triple negative breast cancer Cancer Research. 77: 4495-4495. DOI: 10.1158/1538-7445.Am2017-4495 |
0.306 |
|
| 2017 |
Chen H, Paholak HJ, Luan X, Burnett JP, Stevers NO, Sansanaphongpricha K, Sun D. Abstract 2002: Disrupting immunosuppressive tumor microenvironment via stealthy nanobombs to enhance T-cell anticancer efficacy Cancer Research. 77: 2002-2002. DOI: 10.1158/1538-7445.Am2017-2002 |
0.321 |
|
| 2017 |
Koenigsknecht M, Baker J, Fioritto AF, Tsume Y, Wen B, Dickens J, Yu A, Wysocki J, Shedden K, Bleske B, Lee A, Hasler WL, Amidon G, Sun D. Gastrointestinal Motility and Luminal pH Influence in Vivo Dissolution and Systemic Absorption of Drug Product in Human Gastrointestinal Tract Under Fed and Fasted Conditions Gastroenterology. 152: S206. DOI: 10.1016/S0016-5085(17)30994-0 |
0.703 |
|
| 2016 |
Huang J, Tao C, Yu Y, Yu F, Zhang H, Gao J, Wang D, Chen Y, Gao J, Zhang G, Zhou G, Liu J, Sun Z, Sun D, Zou H, et al. Simultaneous Targeting of Differentiated Breast Cancer Cells and Breast Cancer Stem Cells by Combination of Docetaxel- and Sulforaphane-Loaded Self-Assembled Poly(D, L-lactide-co-glycolide)/Hyaluronic Acid Block Copolymer-Based Nanoparticles. Journal of Biomedical Nanotechnology. 12: 1463-77. PMID 29337484 DOI: 10.1166/Jbn.2016.2234 |
0.36 |
|
| 2016 |
Yu A, Baker JR, Fioritto AF, Wang Y, Luo R, Li S, Wen B, Bly M, Tsume Y, Koenigsknecht MJ, Zhang X, Lionberger R, Amidon GL, Hasler WL, Sun D. Measurement of in vivo Gastrointestinal Release and Dissolution of Three Locally Acting Mesalamine Formulations in Regions of the Human Gastrointestinal Tract. Molecular Pharmaceutics. PMID 28009518 DOI: 10.1021/Acs.Molpharmaceut.6B00641 |
0.76 |
|
| 2016 |
Patel TS, Cinti S, Sun D, Li S, Luo R, Wen B, Gallagher BA, Stevenson JG. Oseltamivir for pandemic influenza preparation: Maximizing the use of an existing stockpile. American Journal of Infection Control. PMID 27816215 DOI: 10.1016/J.Ajic.2016.09.024 |
0.49 |
|
| 2016 |
Mahran RI, Hagras MM, Sun D, Brenner DE. Bringing Curcumin to the Clinic in Cancer Prevention: a Review of Strategies to Enhance Bioavailability and Efficacy. The Aaps Journal. PMID 27783266 DOI: 10.1208/S12248-016-0003-2 |
0.327 |
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| 2016 |
Jia T, Sun Z, Lu Y, Gao J, Zou H, Xie F, Zhang G, Xu H, Sun D, Yu Y, Zhong Y. A dual brain-targeting curcumin-loaded polymersomes ameliorated cognitive dysfunction in intrahippocampal amyloid-β1-42-injected mice. International Journal of Nanomedicine. 11: 3765-75. PMID 27540290 DOI: 10.2147/IJN.S94622 |
0.406 |
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| 2016 |
Paholak HJ, Stevers NO, Chen H, Burnett JP, He M, Korkaya H, McDermott SP, Deol Y, Clouthier SG, Luther T, Li Q, Wicha MS, Sun D. Elimination of epithelial-like and mesenchymal-like breast cancer stem cells to inhibit metastasis following nanoparticle-mediated photothermal therapy. Biomaterials. 104: 145-157. PMID 27450902 DOI: 10.1016/J.Biomaterials.2016.06.045 |
0.375 |
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| 2016 |
Chang Y, Sun D, Zhang Z, Zhang Y, Yao X, Jiang D, Yu Y, Mi L, Chen L, Zhong H, Jiang Y. High Color-Rendering-index Hybrid White LEDs Employing CdSe/ZnS Core/Shell Quantum Dots. Journal of Nanoscience and Nanotechnology. 16: 670-6. PMID 27398506 |
0.353 |
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| 2016 |
Sun L, Burnett J, Gasparyan M, Xu F, Jiang H, Lin CC, Myers I, Korkaya H, Liu Y, Connarn J, He H, Zhang N, Wicha MS, Sun D. Novel cancer stem cell targets during epithelial to mesenchymal transition in PTEN-deficient trastuzumab-resistant breast cancer. Oncotarget. PMID 27285982 DOI: 10.18632/Oncotarget.9839 |
0.375 |
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| 2016 |
Yu F, Huang J, Yu Y, Lu Y, Chen Y, Zhang H, Zhou G, Sun Z, Liu J, Sun D, Zhang G, Zou H, Zhong Y. Glutathione-Responsive Multilayer Coated Gold Nanoparticles for Targeted Gene Delivery. Journal of Biomedical Nanotechnology. 12: 503-15. PMID 27280248 DOI: 10.1166/Jbn.2016.2177 |
0.492 |
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| 2016 |
Passalacqua KD, Charbonneau ME, Donato NJ, Showalter HD, Sun D, Wen B, He M, Sun H, O'Riordan MX, Wobus CE. Anti-infective activity of 2-cyano-3-acrylamide inhibitors with improved drug-like properties against two intracellular pathogens. Antimicrobial Agents and Chemotherapy. PMID 27139470 DOI: 10.1128/Aac.03021-15 |
0.31 |
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| 2016 |
Li Y, Sun D, Palmisano M, Zhou S. Slow drug delivery decreased total body clearance and altered bioavailability of immediate- and controlled-release oxycodone formulations. Pharmacology Research & Perspectives. 4: e00210. PMID 26977300 DOI: 10.1002/Prp2.210 |
0.323 |
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| 2016 |
Ren Y, Wang R, Gao L, Li K, Zhou X, Guo H, Liu C, Han D, Tian J, Ye Q, Hu YT, Sun D, Yuan X, Zhang N. Sequential co-delivery of miR-21 inhibitor followed by burst release doxorubicin using NIR-responsive hollow gold nanoparticle to enhance anticancer efficacy. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 26956593 DOI: 10.1016/J.Jconrel.2016.03.008 |
0.313 |
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| 2016 |
Dickens J, Baker J, Lee A, Koenigsknecht M, Fioritto A, Amidon G, Shedden K, Sun D, Hasler W. Discrimination of Fasting and Fed Manometric Gastric and Small Bowel Contraction Morphology in Healthy Humans Using Principal Components Analysis American Journal of Gastroenterology. 111: S460-S461. DOI: 10.14309/00000434-201610001-01059 |
0.446 |
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| 2016 |
Yu F, Huang J, Yu Y, Lu Y, Chen Y, Zhang H, Zhou G, Sun Z, Liu J, Sun D, Zhang G, Zou H, Zhong Y. Glutathione-responsive multilayer coated gold nanoparticles for targeted gene delivery Journal of Biomedical Nanotechnology. 12: 503-515. DOI: 10.1166/jbn.2016.2177 |
0.374 |
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| 2016 |
Chen H, Luan X, Stevers N, Sansanaphongpricha K, Burnett J, Paholak H, Sun D. Abstract 4912: Boosting immunotherapy via stealthy nanoparticle-mediated photothermal therapy Cancer Research. 76: 4912-4912. DOI: 10.1158/1538-7445.Am2016-4912 |
0.354 |
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| 2016 |
Pollock J, Borkin D, Kempinska K, Purohit T, Li X, Wen B, Zhao T, Miao H, Shukla S, He M, Sun D, Cierpicki T, Grembecka J. Abstract 3898: Structure-based optimization of small molecule inhibitors of the protein-protein interaction between menin and mixed lineage leukemia (MLL) Cancer Research. 76: 3898-3898. DOI: 10.1158/1538-7445.Am2016-3898 |
0.339 |
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| 2016 |
Reed R, Lo M, Lin C, Sun D. Abstract 3091: Development and optimization of a fluorescence polarization-based assay for the discovery of inhibitors of the RBBP4/7-Histone H3 interaction Cancer Research. 76: 3091-3091. DOI: 10.1158/1538-7445.Am2016-3091 |
0.338 |
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| 2016 |
Gasparyan M, Burnett JP, Sun L, Sun D. Abstract 2509: Determining the functional and mechanistic role of homeobox transcription factor Meox1 in breast cancer and breast cancer stem cells Cancer Research. 76: 2509-2509. DOI: 10.1158/1538-7445.Am2016-2509 |
0.395 |
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| 2016 |
Sansanaphongpricha K, Chen H, Sun K, Wen B, Sun D. Abstract 1331: Janus nanostructures for magnetic resonance imaging and enhanced photothermal therapy for cancer theranostics Cancer Research. 76: 1331-1331. DOI: 10.1158/1538-7445.Am2016-1331 |
0.302 |
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| 2016 |
Bai L, Zhao Y, Liu L, Yang C, McEachern D, Stuckey J, Meagher J, Wen B, Sun D, Wang S. Abstract 1250: Antitumor activities of CD161, a structurally novel and orally bioavailable BET inhibitor, in leukemia and triple negative breast cancer cellsin vitroandin vivo Cancer Research. 76: 1250-1250. DOI: 10.1158/1538-7445.Am2016-1250 |
0.344 |
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| 2016 |
Fioritto AF, Yu A, Baker J, Collins K, Wen B, Wang Y, Luo R, Li S, Bleske B, Johnson M, Koenigsknecht M, Hasler WL, Sun D. Mo1318 Direct Comparison of In Vivo Drug Release Profiles of Three Locally-Acting Drug Products of Mesalamine in the Gastrointestinal Tract and Correlation With Systemic Exposure and Fecal Concentrations in Healthy Humans Gastroenterology. 150: S696. DOI: 10.1016/S0016-5085(16)32375-7 |
0.564 |
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| 2015 |
Wu S, Yang Z, Ye R, An D, Li C, Wang Y, Wang Y, Huang Y, Liu H, Li F, He L, Sun D, Yu Y, Li Q, Huang P, et al. Novel variants in MLL confer to bladder cancer recurrence identified by whole-exome sequencing. Oncotarget. PMID 26625313 DOI: 10.18632/Oncotarget.6380 |
0.485 |
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| 2015 |
Wu N, Wei J, Wang Y, Yan J, Qin Y, Tong D, Pang B, Sun D, Sun H, Yu Y, Sun W, Meng X, Zhang C, Bai J, Chen F, et al. Ribosomal L22-like1 (RPL22L1) Promotes Ovarian Cancer Metastasis by Inducing Epithelial-to-Mesenchymal Transition. Plos One. 10: e0143659. PMID 26618703 DOI: 10.1371/journal.pone.0143659 |
0.484 |
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| 2015 |
Chen C, Zhang T, Zhang Q, Feng Z, Zhu C, Yu Y, Li K, Zhao M, Yang J, Liu J, Sun D. Three-Dimensional BC/PEDOT Composite Nanofibers with High Performance for Electrode-Cell Interface. Acs Applied Materials & Interfaces. PMID 26550840 DOI: 10.1021/Acsami.5B07273 |
0.421 |
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| 2015 |
Burnett JP, Korkaya H, Ouzounova MD, Jiang H, Conley SJ, Newman BW, Sun L, Connarn JN, Chen CS, Zhang N, Wicha MS, Sun D. Trastuzumab resistance induces EMT to transform HER2(+) PTEN(-) to a triple negative breast cancer that requires unique treatment options. Scientific Reports. 5: 15821. PMID 26522776 DOI: 10.1038/Srep15821 |
0.728 |
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| 2015 |
Yang S, Li C, Xie Y, Cui X, Li X, Wei J, Zhang Y, Yu Y, Wang Y, Zhang S, Zhang Q, Sun D. Detection of functional polymorphisms influencing the promoter activity of the SAA2 gene and their association with milk production traits in Chinese Holstein cows. Animal Genetics. PMID 26373797 DOI: 10.1111/age.12332 |
0.397 |
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| 2015 |
Wang X, Ma P, Liu J, Zhang Q, Zhang Y, Ding X, Jiang L, Wang Y, Zhang Y, Sun D, Zhang S, Su G, Yu Y. Genome-wide association study in Chinese Holstein cows reveal two candidate genes for somatic cell score as an indicator for mastitis susceptibility. Bmc Genetics. 16: 111. PMID 26370837 DOI: 10.1186/s12863-015-0263-3 |
0.382 |
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| 2015 |
Sun D, Lu J, Zhong Y, Yu Y, Wang Y, Zhang B, Chen Z. Sensitive electrochemical aptamer cytosensor for highly specific detection of cancer cells based on the hybrid nanoelectrocatalysts and enzyme for signal amplification. Biosensors & Bioelectronics. 75: 301-307. PMID 26332382 DOI: 10.1016/j.bios.2015.08.056 |
0.427 |
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| 2015 |
Xiong X, Sun D, Chai H, Shan W, Yu Y, Pu L, Cheng F. MiR-145 functions as a tumor suppressor targeting NUAK1 in human intrahepatic cholangiocarcinoma. Biochemical and Biophysical Research Communications. 465: 262-9. PMID 26255969 DOI: 10.1016/j.bbrc.2015.08.013 |
0.394 |
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| 2015 |
Sun D, Lu J, Chen Z, Yu Y, Mo M. A repeatable assembling and disassembling electrochemical aptamer cytosensor for ultrasensitive and highly selective detection of human liver cancer cells. Analytica Chimica Acta. 885: 166-73. PMID 26231902 DOI: 10.1016/j.aca.2015.05.027 |
0.42 |
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| 2015 |
Hsu EC, Kulp SK, Huang HL, Tu HJ, Salunke SB, Sullivan NJ, Sun D, Wicha MS, Shapiro CL, Chen CS. Function of Integrin-Linked Kinase in Modulating the Stemness of IL-6-Abundant Breast Cancer Cells by Regulating γ-Secretase-Mediated Notch1 Activation in Caveolae. Neoplasia (New York, N.Y.). 17: 497-508. PMID 26152358 DOI: 10.1016/J.Neo.2015.06.001 |
0.341 |
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| 2015 |
Borkin D, He S, Miao H, Kempinska K, Pollock J, Chase J, Purohit T, Malik B, Zhao T, Wang J, Wen B, Zong H, Jones M, Danet-Desnoyers G, Guzman ML, ... ... Sun D, et al. Pharmacologic inhibition of the Menin-MLL interaction blocks progression of MLL leukemia in vivo. Cancer Cell. 27: 589-602. PMID 25817203 DOI: 10.1016/J.Ccell.2015.02.016 |
0.313 |
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| 2015 |
Peterson LF, Sun H, Liu Y, Potu H, Kandarpa M, Ermann M, Courtney SM, Young M, Showalter HD, Sun D, Jakubowiak A, Malek SN, Talpaz M, Donato NJ. Targeting deubiquitinase activity with a novel small-molecule inhibitor as therapy for B-cell malignancies. Blood. 125: 3588-97. PMID 25814533 DOI: 10.1182/Blood-2014-10-605584 |
0.365 |
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| 2015 |
Wang Y, Liu Y, Liu Y, Zhou W, Wang H, Wan G, Sun D, Zhang N, Wang Y. A polymeric prodrug of cisplatin based on pullulan for the targeted therapy against hepatocellular carcinoma. International Journal of Pharmaceutics. 483: 89-100. PMID 25681730 DOI: 10.1016/J.Ijpharm.2015.02.027 |
0.313 |
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| 2015 |
Dong T, Yan Y, Chai H, Chen S, Xiong X, Sun D, Yu Y, Deng L, Cheng F. Pyruvate kinase M2 affects liver cancer cell behavior through up-regulation of HIF-1α and Bcl-xL in culture. Biomedicine & Pharmacotherapy = BioméDecine & PharmacothéRapie. 69: 277-84. PMID 25661370 DOI: 10.1016/j.biopha.2014.12.010 |
0.458 |
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| 2015 |
Yu Y, Chen Z, Jian W, Sun D, Zhang B, Li X, Yao M. Ultrasensitive electrochemical detection of avian influenza A (H7N9) virus DNA based on isothermal exponential amplification coupled with hybridization chain reaction of DNAzyme nanowires. Biosensors & Bioelectronics. 64: 566-71. PMID 25310490 DOI: 10.1016/j.bios.2014.09.080 |
0.376 |
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| 2015 |
Paholak HJ, Stevers NO, Burnett JP, Chen H, McDermott SP, He M, Luther T, Clouthier SG, Wicha MS, Sun D. Abstract 4239: Epithelial-like breast cancer stem cells are preferentially sensitive to nanoparticle-mediated hyperthermia Cancer Research. 75: 4239-4239. DOI: 10.1158/1538-7445.Am2015-4239 |
0.361 |
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| 2015 |
Burnett JP, Shah RB, Paholak HJ, McDermott SP, Tsume Y, Wicha MW, Sun D. Abstract 4076: Combination of docetaxel with sulforaphane synergistically inhibits triple negative breast cancer and cancer stem cells Cancer Research. 75: 4076-4076. DOI: 10.1158/1538-7445.Am2015-4076 |
0.679 |
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| 2015 |
Reed RA, Lo M, Sun D. Abstract 106: Characterization of polycomb repressive complex 2 (PRC2) subunits retinoblastoma-binding protein 4 and 7 (RbBP4/7) in triple-negative breast cancer Cancer Research. 75: 106-106. DOI: 10.1158/1538-7445.Am2015-106 |
0.382 |
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| 2014 |
Chen S, Shao C, Dong T, Chai H, Xiong X, Sun D, Zhang L, Yu Y, Wang P, Cheng F. Transplantation of ATP7B-transduced bone marrow mesenchymal stem cells decreases copper overload in rats. Plos One. 9: e111425. PMID 25375371 DOI: 10.1371/journal.pone.0111425 |
0.381 |
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| 2014 |
Liu Y, Wang Y, Zhang C, Zhou P, Liu Y, An T, Sun D, Zhang N, Wang Y. Core-shell nanoparticles based on pullulan and poly(β-amino) ester for hepatoma-targeted codelivery of gene and chemotherapy agent. Acs Applied Materials & Interfaces. 6: 18712-20. PMID 25289563 DOI: 10.1021/Am504203X |
0.303 |
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| 2014 |
Yu Y, Chen Z, Shi L, Yang F, Pan J, Zhang B, Sun D. Ultrasensitive electrochemical detection of microRNA based on an arched probe mediated isothermal exponential amplification. Analytical Chemistry. 86: 8200-5. PMID 25054588 DOI: 10.1021/ac501505a |
0.375 |
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| 2014 |
Sun D, Sun W, Yu Y, Li Z, Deng Z, Lin S. A new glutarimide derivative from marine sponge-derived Streptomyces anulatus S71. Natural Product Research. 28: 1602-6. PMID 24949797 DOI: 10.1080/14786419.2014.928877 |
0.361 |
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| 2014 |
Zhang Y, Li Q, Ye S, Faruque MO, Yu Y, Sun D, Zhang S, Wang Y. New variants in the melanocortin 1 receptor gene (MC1R) in Asian cattle. Animal Genetics. 45: 609-10. PMID 24702190 DOI: 10.1111/age.12160 |
0.351 |
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| 2014 |
Huang J, Zhang H, Yu Y, Chen Y, Wang D, Zhang G, Zhou G, Liu J, Sun Z, Sun D, Lu Y, Zhong Y. Biodegradable self-assembled nanoparticles of poly (D,L-lactide-co-glycolide)/hyaluronic acid block copolymers for target delivery of docetaxel to breast cancer. Biomaterials. 35: 550-66. PMID 24135268 DOI: 10.1016/J.Biomaterials.2013.09.089 |
0.506 |
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| 2014 |
Abulwerdi F, Liao C, Liu M, Azmi AS, Aboukameel A, Mady AS, Gulappa T, Cierpicki T, Owens S, Zhang T, Sun D, Stuckey JA, Mohammad RM, Nikolovska-Coleska Z. A novel small-molecule inhibitor of mcl-1 blocks pancreatic cancer growth in vitro and in vivo. Molecular Cancer Therapeutics. 13: 565-75. PMID 24019208 DOI: 10.1158/1535-7163.Mct-12-0767 |
0.373 |
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| 2014 |
Pan J, Chen Z, Yao M, Li X, Li Y, Sun D, Yu Y. A two-electrode system-based electrochemiluminescence detection for microfluidic capillary electrophoresis and its application in pharmaceutical analysis. Luminescence : the Journal of Biological and Chemical Luminescence. 29: 427-32. PMID 23913856 DOI: 10.1002/bio.2565 |
0.364 |
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| 2014 |
Gu M, Yu Y, Gunaherath GM, Gunatilaka AA, Li D, Sun D. Structure-activity relationship (SAR) of withanolides to inhibit Hsp90 for its activity in pancreatic cancer cells. Investigational New Drugs. 32: 68-74. PMID 23887853 DOI: 10.1007/S10637-013-9987-Y |
0.525 |
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| 2014 |
Zhang H, Sun S, Chen Q, Zhang G, Zhang Z, Sun D, Zhang W. A Screening Method for Potential Anti-pancreatic Cancer Candidate Compounds Based on Hsp90-Cdc37 Interaction Model in vitro Letters in Drug Design & Discovery. 12: 66-71. DOI: 10.2174/1570180811666140725185235 |
0.305 |
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| 2014 |
Sun L, Burnett JP, Gasparyan M, Korkaya H, Jiang H, Liu Y, Connarn J, Wicha M, Sun D. Abstract 218: MEOX-1 as a novel cancer stem cell target for treatment of trastuzumab-resistant Her2+ breast cancers Cancer Research. 74: 218-218. DOI: 10.1158/1538-7445.Am2014-218 |
0.393 |
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| 2013 |
Lin L, Hutzen B, Lee HF, Peng Z, Wang W, Zhao C, Lin HJ, Sun D, Li PK, Li C, Korkaya H, Wicha MS, Lin J. Evaluation of STAT3 signaling in ALDH+ and ALDH+/CD44+/CD24- subpopulations of breast cancer cells. Plos One. 8: e82821. PMID 24376586 DOI: 10.1371/Journal.Pone.0082821 |
0.553 |
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| 2013 |
Wang XS, Zhang Y, He YH, Ma PP, Fan LJ, Wang YC, Zhang YI, Sun DX, Zhang SL, Wang CD, Song JZ, Yu Y. Aberrant promoter methylation of the CD4 gene in peripheral blood cells of mastitic dairy cows. Genetics and Molecular Research : Gmr. 12: 6228-39. PMID 24338418 DOI: 10.4238/2013.December.4.10 |
0.372 |
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| 2013 |
Li X, Srinivasan SR, Connarn J, Ahmad A, Young ZT, Kabza AM, Zuiderweg ER, Sun D, Gestwicki JE. Analogs of the Allosteric Heat Shock Protein 70 (Hsp70) Inhibitor, MKT-077, as Anti-Cancer Agents. Acs Medicinal Chemistry Letters. 4. PMID 24312699 DOI: 10.1021/Ml400204N |
0.361 |
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| 2013 |
Jia X, Zhang F, Bai J, Gao L, Zhang X, Sun H, Sun D, Guan R, Sun W, Xu L, Yue Z, Yu Y, Fu S. Combinational analysis of linkage and exome sequencing identifies the causative mutation in a Chinese family with congenital cataract. Bmc Medical Genetics. 14: 107. PMID 24103489 DOI: 10.1186/1471-2350-14-107 |
0.355 |
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| 2013 |
Yu L, Zhao Y, Quan C, Ji W, Zhu J, Huang Y, Guan R, Sun D, Jin Y, Meng X, Zhang C, Yu Y, Bai J, Sun W, Fu S. Gemcitabine eliminates double minute chromosomes from human ovarian cancer cells. Plos One. 8: e71988. PMID 23991020 DOI: 10.1371/journal.pone.0071988 |
0.473 |
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| 2013 |
Chen H, Paholak H, Ito M, Sansanaphongpricha K, Qian W, Che Y, Sun D. 'Living' PEGylation on gold nanoparticles to optimize cancer cell uptake by controlling targeting ligand and charge densities. Nanotechnology. 24: 355101. PMID 23940104 DOI: 10.1088/0957-4484/24/35/355101 |
0.3 |
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| 2013 |
Li Y, Zhang T, Li X, Zou P, Schwartz SJ, Sun D. Kinetics of sulforaphane in mice after consumption of sulforaphane-enriched broccoli sprout preparation. Molecular Nutrition & Food Research. 57: 2128-36. PMID 23929742 DOI: 10.1002/Mnfr.201300210 |
0.301 |
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| 2013 |
Wang D, Huang J, Wang X, Yu Y, Zhang H, Chen Y, Liu J, Sun Z, Zou H, Sun D, Zhou G, Zhang G, Lu Y, Zhong Y. The eradication of breast cancer cells and stem cells by 8-hydroxyquinoline-loaded hyaluronan modified mesoporous silica nanoparticle-supported lipid bilayers containing docetaxel. Biomaterials. 34: 7662-73. PMID 23859657 DOI: 10.1016/J.Biomaterials.2013.06.042 |
0.535 |
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| 2013 |
Zhang T, Li Y, Zou P, Yu JY, McEachern D, Wang S, Sun D. Physiologically based pharmacokinetic and pharmacodynamic modeling of an antagonist (SM-406/AT-406) of multiple inhibitor of apoptosis proteins (IAPs) in a mouse xenograft model of human breast cancer. Biopharmaceutics & Drug Disposition. 34: 348-59. PMID 23813446 DOI: 10.1002/Bdd.1850 |
0.338 |
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| 2013 |
Zhao Y, Yu S, Sun W, Liu L, Lu J, McEachern D, Shargary S, Bernard D, Li X, Zhao T, Zou P, Sun D, Wang S. A potent small-molecule inhibitor of the MDM2-p53 interaction (MI-888) achieved complete and durable tumor regression in mice. Journal of Medicinal Chemistry. 56: 5553-61. PMID 23786219 DOI: 10.1021/Jm4005708 |
0.336 |
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| 2013 |
Ding X, Zhang Z, Li X, Wang S, Wu X, Sun D, Yu Y, Liu J, Wang Y, Zhang Y, Zhang S, Zhang Y, Zhang Q. Accuracy of genomic prediction for milk production traits in the Chinese Holstein population using a reference population consisting of cows. Journal of Dairy Science. 96: 5315-23. PMID 23746588 DOI: 10.3168/jds.2012-6194 |
0.36 |
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| 2013 |
Zhao Y, Liu L, Sun W, Lu J, McEachern D, Li X, Yu S, Bernard D, Ochsenbein P, Ferey V, Carry JC, Deschamps JR, Sun D, Wang S. Diastereomeric spirooxindoles as highly potent and efficacious MDM2 inhibitors. Journal of the American Chemical Society. 135: 7223-34. PMID 23641733 DOI: 10.1021/Ja3125417 |
0.318 |
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| 2013 |
Zhou G, Lu Y, Zhang H, Chen Y, Yu Y, Gao J, Sun D, Zhang G, Zou H, Zhong Y. A novel pulsed drug-delivery system: polyelectrolyte layer-by-layer coating of chitosan-alginate microgels. International Journal of Nanomedicine. 8: 877-87. PMID 23486565 DOI: 10.2147/Ijn.S38144 |
0.479 |
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| 2013 |
Miyata Y, Li X, Lee HF, Jinwal UK, Srinivasan SR, Seguin SP, Young ZT, Brodsky JL, Dickey CA, Sun D, Gestwicki JE. Synthesis and initial evaluation of YM-08, a blood-brain barrier permeable derivative of the heat shock protein 70 (Hsp70) inhibitor MKT-077, which reduces tau levels. Acs Chemical Neuroscience. 4: 930-9. PMID 23472668 DOI: 10.1021/Cn300210G |
0.554 |
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| 2013 |
Yestrepsky BD, Xu Y, Breen ME, Li X, Rajeswaran WG, Ryu JG, Sorenson RJ, Tsume Y, Wilson MW, Zhang W, Sun D, Sun H, Larsen SD. Novel inhibitors of bacterial virulence: development of 5,6-dihydrobenzo[h]quinazolin-4(3H)-ones for the inhibition of group A streptococcal streptokinase expression. Bioorganic & Medicinal Chemistry. 21: 1880-97. PMID 23433668 DOI: 10.1016/J.Bmc.2013.01.046 |
0.638 |
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| 2013 |
Lin YW, Ren LL, Xiong H, Du W, Yu YN, Sun TT, Weng YR, Wang ZH, Wang JL, Wang YC, Cui Y, Sun DF, Han ZG, Shen N, Zou W, et al. Role of STAT3 and vitamin D receptor in EZH2-mediated invasion of human colorectal cancer. The Journal of Pathology. 230: 277-90. PMID 23424038 DOI: 10.1002/Path.4179 |
0.437 |
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| 2013 |
Yang Q, Liu H, Qu L, Fu X, Yu Y, Yu G, Tian H, Yu Y, Sun D, Peng J, Bao F, Yuan C, Lu N, Li J, Zhang Y, et al. Investigation of 20 non-HLA (human leucocyte antigen) psoriasis susceptibility loci in Chinese patients with psoriatic arthritis and psoriasis vulgaris. The British Journal of Dermatology. 168: 1060-5. PMID 23252691 DOI: 10.1111/bjd.12142 |
0.358 |
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| 2013 |
Burnett J, Korkaya H, Newman B, Conley S, Connarn J, Sun L, Lee H, Ouzounova M, Wicha M, Sun D. Abstract 913: Natural product sulforaphane selectively inhibits breast cancer stem cells in basal and trastuzumab resistant Her2+ breast cancer. Cancer Research. 73: 913-913. DOI: 10.1158/1538-7445.Am2013-913 |
0.776 |
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| 2013 |
Shayman J, Arthur J, Seyfried T, Wilson M, Tsume Y, Li X, Sun D, Larsen S. Property based designed inhibitors of glycosphingolipid synthesis lower ganglioside GM2 in the Sandhoff mouse Molecular Genetics and Metabolism. 108: S85. DOI: 10.1016/J.Ymgme.2012.11.227 |
0.62 |
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| 2012 |
Zhang X, Qiao H, Zhao Y, Wang X, Sun H, Liu A, Xu L, Sun D, Jin Y, Yu Y, Meng X, Bai J, Chen F, Fu S. Association of single nucleotide polymorphisms in TCF2 with type 2 diabetes susceptibility in a Han Chinese population. Plos One. 7: e52938. PMID 23300827 DOI: 10.1371/journal.pone.0052938 |
0.359 |
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| 2012 |
Zhang Y, Fan X, Sun D, Wang Y, Yu Y, Xie Y, Zhang S, Zhang Y. A novel method for rapid and reliable detection of complex vertebral malformation and bovine leukocyte adhesion deficiency in Holstein cattle. Journal of Animal Science and Biotechnology. 3: 24. PMID 22958243 DOI: 10.1186/2049-1891-3-24 |
0.381 |
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| 2012 |
He Y, Yu Y, Zhang Y, Song J, Mitra A, Zhang Y, Wang Y, Sun D, Zhang S. Genome-wide bovine H3K27me3 modifications and the regulatory effects on genes expressions in peripheral blood lymphocytes. Plos One. 7: e39094. PMID 22761725 DOI: 10.1371/journal.pone.0039094 |
0.4 |
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| 2012 |
Newman B, Liu Y, Lee HF, Sun D, Wang Y. HSP90 inhibitor 17-AAG selectively eradicates lymphoma stem cells. Cancer Research. 72: 4551-61. PMID 22751135 DOI: 10.1158/0008-5472.Can-11-3600 |
0.78 |
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| 2012 |
Burnett J, Newman B, Sun D. Targeting cancer stem cells with natural products. Current Drug Targets. 13: 1054-64. PMID 22594473 DOI: 10.2174/138945012802009062 |
0.729 |
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| 2012 |
Zou P, Zheng N, Yu Y, Yu S, Sun W, McEachem D, Yang Y, Yu LX, Wang S, Sun D. Preclinical pharmacokinetics of MI-219, a novel human double minute 2 (HDM2) inhibitor and prediction of human pharmacokinetics. Journal of Pharmacy & Pharmaceutical Sciences : a Publication of the Canadian Society For Pharmaceutical Sciences, Sociã©Tã© Canadienne Des Sciences Pharmaceutiques. 15: 265-80. PMID 22579006 DOI: 10.18433/J34S4N |
0.495 |
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| 2012 |
Yu S, Zhang G, Zhang W, Luo H, Qiu L, Liu Q, Sun D, Wang PG, Wang F. Synthesis and biological activities of a 3'-azido analogue of Doxorubicin against drug-resistant cancer cells. International Journal of Molecular Sciences. 13: 3671-84. PMID 22489175 DOI: 10.3390/Ijms13033671 |
0.333 |
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| 2012 |
Li Y, Karagöz GE, Seo YH, Zhang T, Jiang Y, Yu Y, Duarte AM, Schwartz SJ, Boelens R, Carroll K, Rüdiger SG, Sun D. Sulforaphane inhibits pancreatic cancer through disrupting Hsp90-p50(Cdc37) complex and direct interactions with amino acids residues of Hsp90. The Journal of Nutritional Biochemistry. 23: 1617-26. PMID 22444872 DOI: 10.1016/J.Jnutbio.2011.11.004 |
0.535 |
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| 2012 |
Zou P, Yu Y, Zheng N, Yang Y, Paholak HJ, Yu LX, Sun D. Applications of human pharmacokinetic prediction in first-in-human dose estimation. The Aaps Journal. 14: 262-81. PMID 22407287 DOI: 10.1208/S12248-012-9332-Y |
0.464 |
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| 2012 |
Zhu J, Lee H, Korkaya H, Liu S, McDemott S, Wicha MS, Sun D. Abstract LB-100: Computational assessment of oncogenic pathways modulated by vorinostat in breast cancer stem cells Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-100 |
0.582 |
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| 2011 |
Li Y, Zhang T, Schwartz SJ, Sun D. Sulforaphane potentiates the efficacy of 17-allylamino 17-demethoxygeldanamycin against pancreatic cancer through enhanced abrogation of Hsp90 chaperone function. Nutrition and Cancer. 63: 1151-9. PMID 21875325 DOI: 10.1080/01635581.2011.596645 |
0.378 |
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| 2011 |
Yu Y, Zick S, Li X, Zou P, Wright B, Sun D. Examination of the pharmacokinetics of active ingredients of ginger in humans. The Aaps Journal. 13: 417-26. PMID 21638149 DOI: 10.1208/S12248-011-9286-5 |
0.479 |
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| 2011 |
Sun H, Liu L, Lu J, Bai L, Li X, Nikolovska-Coleska Z, McEachern D, Yang CY, Qiu S, Yi H, Sun D, Wang S. Potent bivalent Smac mimetics: effect of the linker on binding to inhibitor of apoptosis proteins (IAPs) and anticancer activity. Journal of Medicinal Chemistry. 54: 3306-18. PMID 21462933 DOI: 10.1021/Jm101651B |
0.345 |
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| 2011 |
Cai Q, Sun H, Peng Y, Lu J, Nikolovska-Coleska Z, McEachern D, Liu L, Qiu S, Yang CY, Miller R, Yi H, Zhang T, Sun D, Kang S, Guo M, et al. A potent and orally active antagonist (SM-406/AT-406) of multiple inhibitor of apoptosis proteins (IAPs) in clinical development for cancer treatment. Journal of Medicinal Chemistry. 54: 2714-26. PMID 21443232 DOI: 10.1021/Jm101505D |
0.373 |
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| 2011 |
Li Y, Wicha MS, Schwartz SJ, Sun D. Implications of cancer stem cell theory for cancer chemoprevention by natural dietary compounds. The Journal of Nutritional Biochemistry. 22: 799-806. PMID 21295962 DOI: 10.1016/J.Jnutbio.2010.11.001 |
0.366 |
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| 2011 |
Grembecka J, He S, Shi A, Purohit T, Muntean AG, Li X, Hartley T, Sun D, Hess JL, Cierpicki T. Targeting Menin-MLL Interaction to Inhibit MLL Fusion Oncoproteins in Leukemia Blood. 118: 2497-2497. DOI: 10.1182/Blood.V118.21.2497.2497 |
0.322 |
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| 2011 |
Wang S, Sun W, Yu S, Zhao Y, Kumar S, McEachern D, Liu L, Bernard D, Sun D, Zou P, Li X, Yi H, Stuckey J, Long J, Malek S, et al. Abstract LB-204: Highly potent and optimized small-molecule inhibitors of MDM2 achieve complete tumor regression in animal models of solid tumors and leukemia. Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Lb-204 |
0.35 |
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| 2011 |
Newman BW, Zhang Q, Lu Y, Zhai J, Ding Y, Ma W, Fan H, Long J, Zhang H, Wang M, Chen Y, Sun D. Abstract 3350: Inhibition of breast cancer and cancer stem cells via a novel micheliolide analogue CY-9 Cancer Research. 71: 3350-3350. DOI: 10.1158/1538-7445.Am2011-3350 |
0.755 |
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| 2010 |
Yu Y, Sun D. Superparamagnetic iron oxide nanoparticle 'theranostics' for multimodality tumor imaging, gene delivery, targeted drug and prodrug delivery. Expert Review of Clinical Pharmacology. 3: 117-30. PMID 22111537 DOI: 10.1586/ecp.09.39 |
0.432 |
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| 2010 |
Zou P, Yu Y, Wang YA, Zhong Y, Welton A, Galbán C, Wang S, Sun D. Superparamagnetic iron oxide nanotheranostics for targeted cancer cell imaging and pH-dependent intracellular drug release. Molecular Pharmaceutics. 7: 1974-84. PMID 20845930 DOI: 10.1021/Mp100273T |
0.517 |
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| 2010 |
Zhang T, Li Y, Zhu Z, Gu M, Newman B, Sun D. MEK inhibition potentiates the activity of Hsp90 inhibitor 17-AAG against pancreatic cancer cells. Molecular Pharmaceutics. 7: 1576-84. PMID 20669973 DOI: 10.1021/Mp900321A |
0.736 |
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| 2010 |
Liu Q, Zhang H, Zhou G, Xie S, Zou H, Yu Y, Li G, Sun D, Zhang G, Lu Y, Zhong Y. In vitro and in vivo study of thymosin alpha1 biodegradable in situ forming poly(lactide-co-glycolide) implants. International Journal of Pharmaceutics. 397: 122-9. PMID 20650309 DOI: 10.1016/J.Ijpharm.2010.07.015 |
0.473 |
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| 2010 |
Zhu Z, Xu X, Yu Y, Graham M, Prince ME, Carey TE, Sun D. Silencing heat shock protein 27 decreases metastatic behavior of human head and neck squamous cell cancer cells in vitro. Molecular Pharmaceutics. 7: 1283-90. PMID 20540527 DOI: 10.1021/Mp100073S |
0.517 |
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| 2010 |
Jiang Y, Bernard D, Yu Y, Xie Y, Zhang T, Li Y, Burnett JP, Fu X, Wang S, Sun D. Split Renilla luciferase protein fragment-assisted complementation (SRL-PFAC) to characterize Hsp90-Cdc37 complex and identify critical residues in protein/protein interactions. The Journal of Biological Chemistry. 285: 21023-36. PMID 20413594 DOI: 10.1074/Jbc.M110.103390 |
0.466 |
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| 2010 |
Li Y, Zhang T, Korkaya H, Liu S, Lee HF, Newman B, Yu Y, Clouthier SG, Schwartz SJ, Wicha MS, Sun D. Sulforaphane, a dietary component of broccoli/broccoli sprouts, inhibits breast cancer stem cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 2580-90. PMID 20388854 DOI: 10.1158/1078-0432.Ccr-09-2937 |
0.79 |
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| 2010 |
Yu Y, Fang L, Sun D. Biodistribution of HuCC49DeltaCH2-beta-galactosidase in colorectal cancer xenograft model. International Journal of Pharmaceutics. 386: 208-15. PMID 19944136 DOI: 10.1016/J.Ijpharm.2009.11.020 |
0.478 |
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| 2010 |
Yu Y, Hamza A, Zhang T, Gu M, Zou P, Newman B, Li Y, Gunatilaka AA, Zhan CG, Sun D. Withaferin A targets heat shock protein 90 in pancreatic cancer cells. Biochemical Pharmacology. 79: 542-51. PMID 19769945 DOI: 10.1016/J.Bcp.2009.09.017 |
0.767 |
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| 2010 |
Kakarala M, Sun D, Wicha MS. Abstract CN08-02: Implications of the cancer stem cell hypothesis for breast cancer prevention Cancer Prevention Research. 3. DOI: 10.1158/1940-6207.Prev-10-Cn08-02 |
0.361 |
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| 2010 |
Li Y, Zhang T, Korkaya H, Liu S, Lee H, Newman B, Yu Y, Clouthier S, Schwartz S, Wicha M, Sun D. Abstract 4271: Sulforaphane, a Dietary Component of Broccoli/Broccoli Sprouts, Inhibits Breast Cancer Stem Cells Cancer Research. 70: 4271-4271. DOI: 10.1158/1538-7445.Am10-4271 |
0.793 |
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| 2010 |
Zhu Z, Xu X, Yu Y, Graham M, Liu G, Prince M, Carey T, Sun D. Abstract 3392: Heat shock protein 27 increases metastasis of human head and neck squamous cancer cellsin vitro Cancer Research. 70: 3392-3392. DOI: 10.1158/1538-7445.Am10-3392 |
0.529 |
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| 2010 |
Jiang Y, Bernard D, Yu Y, Zhang T, Li Y, Fu X, Wang S, Sun D. Abstract 2672: Characterization of Hsp90/Cdc37 interaction and their critical residues using luciferase fragment complementation imaging Cancer Research. 70: 2672-2672. DOI: 10.1158/1538-7445.Am10-2672 |
0.478 |
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| 2009 |
Zhang T, Li Y, Yu Y, Zou P, Jiang Y, Sun D. Characterization of celastrol to inhibit hsp90 and cdc37 interaction. The Journal of Biological Chemistry. 284: 35381-9. PMID 19858214 DOI: 10.1074/Jbc.M109.051532 |
0.5 |
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| 2009 |
Shin HC, Kim HR, Cho HJ, Yi H, Cho SM, Lee DG, Abd El-Aty AM, Kim JS, Sun D, Amidon GL. Comparative gene expression of intestinal metabolizing enzymes. Biopharmaceutics & Drug Disposition. 30: 411-21. PMID 19746353 DOI: 10.1002/Bdd.675 |
0.494 |
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| 2009 |
Li Y, Zhang T, Jiang Y, Lee HF, Schwartz SJ, Sun D. (-)-Epigallocatechin-3-gallate inhibits Hsp90 function by impairing Hsp90 association with cochaperones in pancreatic cancer cell line Mia Paca-2. Molecular Pharmaceutics. 6: 1152-9. PMID 19438225 DOI: 10.1021/Mp900037P |
0.575 |
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| 2009 |
Li Y, Zhang T, Schwartz SJ, Sun D. New developments in Hsp90 inhibitors as anti-cancer therapeutics: mechanisms, clinical perspective and more potential. Drug Resistance Updates : Reviews and Commentaries in Antimicrobial and Anticancer Chemotherapy. 12: 17-27. PMID 19179103 DOI: 10.1016/J.Drup.2008.12.002 |
0.352 |
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| 2008 |
Shen J, Woodward R, Kedenburg JP, Liu X, Chen M, Fang L, Sun D, Wang PG. Histone deacetylase inhibitors through click chemistry. Journal of Medicinal Chemistry. 51: 7417-27. PMID 19007204 DOI: 10.1021/Jm8005355 |
0.325 |
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| 2008 |
Polli JE, Abrahamsson BS, Yu LX, Amidon GL, Baldoni JM, Cook JA, Fackler P, Hartauer K, Johnston G, Krill SL, Lipper RA, Malick WA, Shah VP, Sun D, Winkle HN, et al. Summary workshop report: bioequivalence, biopharmaceutics classification system, and beyond. The Aaps Journal. 10: 373-9. PMID 18679807 DOI: 10.1208/S12248-008-9040-9 |
0.489 |
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| 2008 |
Fang L, Sun D. Predictive physiologically based pharmacokinetic model for antibody-directed enzyme prodrug therapy. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 36: 1153-65. PMID 18356268 DOI: 10.1124/Dmd.107.019182 |
0.313 |
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| 2008 |
Cao X, Bloomston M, Zhang T, Frankel WL, Jia G, Wang B, Hall NC, Koch RM, Cheng H, Knopp MV, Sun D. Synergistic antipancreatic tumor effect by simultaneously targeting hypoxic cancer cells with HSP90 inhibitor and glycolysis inhibitor. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 1831-9. PMID 18347186 DOI: 10.1158/1078-0432.Ccr-07-1607 |
0.381 |
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| 2008 |
Cao X, Jia G, Zhang T, Yang M, Wang B, Wassenaar PA, Cheng H, Knopp MV, Sun D. Non-invasive MRI tumor imaging and synergistic anticancer effect of HSP90 inhibitor and glycolysis inhibitor in RIP1-Tag2 transgenic pancreatic tumor model. Cancer Chemotherapy and Pharmacology. 62: 985-94. PMID 18253734 DOI: 10.1007/S00280-008-0688-8 |
0.33 |
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| 2008 |
Zhang T, Hamza A, Cao X, Wang B, Yu S, Zhan CG, Sun D. A novel Hsp90 inhibitor to disrupt Hsp90/Cdc37 complex against pancreatic cancer cells. Molecular Cancer Therapeutics. 7: 162-70. PMID 18202019 DOI: 10.1158/1535-7163.Mct-07-0484 |
0.361 |
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| 2008 |
Cui H, Shen J, Lu D, Zhang T, Zhang W, Sun D, Wang PG. 4-Aryl-1,3,2-oxathiazolylium-5-olate: a novel GST inhibitor to release JNK and activate c-Jun for cancer therapy. Cancer Chemotherapy and Pharmacology. 62: 509-15. PMID 18008069 DOI: 10.1007/S00280-007-0632-3 |
0.338 |
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| 2007 |
Kim HR, Park SW, Cho HJ, Chae KA, Sung JM, Kim JS, Landowski CP, Sun D, Abd El-Aty AM, Amidon GL, Shin HC. Comparative gene expression profiles of intestinal transporters in mice, rats and humans. Pharmacological Research. 56: 224-36. PMID 17681807 DOI: 10.1016/J.Phrs.2007.06.005 |
0.71 |
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| 2007 |
Battisti RF, Zhong Y, Fang L, Gibbs S, Shen J, Nadas J, Zhang G, Sun D. Modifying the sugar moieties of daunorubicin overcomes P-gp-mediated multidrug resistance. Molecular Pharmaceutics. 4: 140-53. PMID 17274671 DOI: 10.1021/Mp060075V |
0.305 |
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| 2007 |
Cao X, Fang L, Gibbs S, Huang Y, Dai Z, Wen P, Zheng X, Sadee W, Sun D. Glucose uptake inhibitor sensitizes cancer cells to daunorubicin and overcomes drug resistance in hypoxia. Cancer Chemotherapy and Pharmacology. 59: 495-505. PMID 16906425 DOI: 10.1007/S00280-006-0291-9 |
0.357 |
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| 2006 |
Nadas J, Sun D. Anthracyclines as effective anticancer drugs. Expert Opinion On Drug Discovery. 1: 549-68. PMID 23506066 DOI: 10.1517/17460441.1.6.549 |
0.337 |
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| 2006 |
Cao X, Gibbs ST, Fang L, Miller HA, Landowski CP, Shin HC, Lennernas H, Zhong Y, Amidon GL, Yu LX, Sun D. Why is it challenging to predict intestinal drug absorption and oral bioavailability in human using rat model. Pharmaceutical Research. 23: 1675-86. PMID 16841194 DOI: 10.1007/S11095-006-9041-2 |
0.735 |
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| 2006 |
Zhang G, Fang L, Zhu L, Zhong Y, Wang PG, Sun D. Syntheses and biological activities of 3'-azido disaccharide analogues of daunorubicin against drug-resistant leukemia. Journal of Medicinal Chemistry. 49: 1792-9. PMID 16509594 DOI: 10.1021/Jm050916M |
0.325 |
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| 2006 |
Fang L, Zhang G, Li C, Zheng X, Zhu L, Xiao JJ, Szakacs G, Nadas J, Chan KK, Wang PG, Sun D. Discovery of a daunorubicin analogue that exhibits potent antitumor activity and overcomes P-gp-mediated drug resistance. Journal of Medicinal Chemistry. 49: 932-41. PMID 16451059 DOI: 10.1021/Jm050800Q |
0.344 |
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| 2006 |
Zhang G, Fang L, Zhu L, Sun D, Wang PG. Syntheses and biological activity of bisdaunorubicins. Bioorganic & Medicinal Chemistry. 14: 426-34. PMID 16182536 DOI: 10.1016/J.Bmc.2005.08.014 |
0.325 |
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| 2005 |
Zhu L, Cao X, Chen W, Zhang G, Sun D, Wang PG. Syntheses and biological activities of daunorubicin analogs with uncommon sugars. Bioorganic & Medicinal Chemistry. 13: 6381-7. PMID 16055335 DOI: 10.1016/J.Bmc.2005.06.053 |
0.34 |
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| 2005 |
Cao X, Yu LX, Barbaciru C, Landowski CP, Shin HC, Gibbs S, Miller HA, Amidon GL, Sun D. Permeability dominates in vivo intestinal absorption of P-gp substrate with high solubility and high permeability. Molecular Pharmaceutics. 2: 329-40. PMID 16053336 DOI: 10.1021/Mp0499104 |
0.73 |
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| 2005 |
Zhou R, Moench P, Heran C, Lu X, Mathias N, Faria TN, Wall DA, Hussain MA, Smith RL, Sun D. pH-dependent dissolution in vitro and absorption in vivo of weakly basic drugs: development of a canine model. Pharmaceutical Research. 22: 188-92. PMID 15783065 DOI: 10.1007/S11095-004-1185-3 |
0.304 |
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| 2004 |
Landowski CP, Anderle P, Sun D, Sadee W, Amidon GL. Transporter and ion channel gene expression after Caco-2 cell differentiation using 2 different microarray technologies. The Aaps Journal. 6: e21. PMID 15760106 DOI: 10.1208/Aapsj060321 |
0.717 |
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| 2004 |
Sun D, Yu LX, Hussain MA, Wall DA, Smith RL, Amidon GL. In vitro testing of drug absorption for drug 'developability' assessment: forming an interface between in vitro preclinical data and clinical outcome. Current Opinion in Drug Discovery & Development. 7: 75-85. PMID 14982151 |
0.463 |
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| 2003 |
Shin HC, Landowski CP, Sun D, Vig BS, Kim I, Mittal S, Lane M, Rosania G, Drach JC, Amidon GL. Functional expression and characterization of a sodium-dependent nucleoside transporter hCNT2 cloned from human duodenum. Biochemical and Biophysical Research Communications. 307: 696-703. PMID 12893280 DOI: 10.1016/S0006-291X(03)01259-2 |
0.792 |
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| 2003 |
Qi X, Liu RR, Sun D, Ackermann C, Hou H. Convolution method to predict drug concentration profiles of 2,3,5,6-tetramethylpyrazine following transdermal application. International Journal of Pharmaceutics. 259: 39-45. PMID 12787634 DOI: 10.1016/S0378-5173(03)00184-4 |
0.322 |
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| 2003 |
Landowski CP, Sun D, Foster DR, Menon SS, Barnett JL, Welage LS, Ramachandran C, Amidon GL. Gene expression in the human intestine and correlation with oral valacyclovir pharmacokinetic parameters. The Journal of Pharmacology and Experimental Therapeutics. 306: 778-86. PMID 12750437 DOI: 10.1124/Jpet.103.051011 |
0.782 |
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| 2002 |
Sun D, Lennernas H, Welage LS, Barnett JL, Landowski CP, Foster D, Fleisher D, Lee KD, Amidon GL. Comparison of human duodenum and Caco-2 gene expression profiles for 12,000 gene sequences tags and correlation with permeability of 26 drugs. Pharmaceutical Research. 19: 1400-16. PMID 12425456 DOI: 10.1023/A:1020483911355 |
0.744 |
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| 2001 |
Sun D, Landowski CP, Chu X, Wallsten R, Komorowski TE, Fleisher D, Amidon GL. Drug inhibition of Gly-Sar uptake and hPepT1 localization using hPepT1-GFP fusion protein. Aaps Pharmsci. 3: E2. PMID 11741253 DOI: 10.1208/Ps030102 |
0.735 |
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