Vikram Khurana - Publications

Whitehead Institute, Cambridge, MA, United States 
Neurodegeneration (Drosophila, Yeast, Stem Cell)

43 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Sanz R, Ovando-Roche P, Udeshi ND, Carr SA, Chung CY, Khurana V. In Situ Peroxidase Labeling and Mass Spectrometry of Alpha-Synuclein in Rat Cortical Neurons. Methods in Molecular Biology (Clifton, N.J.). 1948: 235-246. PMID 30771182 DOI: 10.1007/978-1-4939-9124-2_18  0.8
2018 Vincent BM, Tardiff DF, Piotrowski JS, Aron R, Lucas MC, Chung CY, Bacherman H, Chen Y, Pires M, Subramaniam R, Doshi DB, Sadlish H, Raja WK, Solís EJ, Khurana V, et al. Inhibiting Stearoyl-CoA Desaturase Ameliorates α-Synuclein Cytotoxicity. Cell Reports. 25: 2742-2754.e31. PMID 30517862 DOI: 10.1016/J.Celrep.2018.11.028  0.8
2017 Jarosz DF, Khurana V. Specification of Physiologic and Disease States by Distinct Proteins and Protein Conformations. Cell. 171: 1001-1014. PMID 29149602 DOI: 10.1016/J.Cell.2017.10.047  0.96
2017 Mittal S, Bjørnevik K, Im DS, Flierl A, Dong X, Locascio JJ, Abo KM, Long E, Jin M, Xu B, Xiang YK, Rochet JC, Engeland A, Rizzu P, Heutink P, ... ... Khurana V, et al. β2-Adrenoreceptor is a regulator of the α-synuclein gene driving risk of Parkinson's disease. Science (New York, N.Y.). 357: 891-898. PMID 28860381 DOI: 10.1126/Science.Aaf3934  0.52
2017 Khurana V, Chung CY, Tardiff DF. From Yeast to Patients: The Audacity and Vision of Susan Lindquist. Cell Systems. 4: 147-148. PMID 28231447 DOI: 10.1016/J.Cels.2017.02.007  0.8
2017 Chung CY, Khurana V, Yi S, Sahni N, Loh KH, Auluck PK, Baru V, Udeshi ND, Freyzon Y, Carr SA, Hill DE, Vidal M, Ting AY, Lindquist S. In Situ Peroxidase Labeling and Mass-Spectrometry Connects Alpha-Synuclein Directly to Endocytic Trafficking and mRNA Metabolism in Neurons. Cell Systems. PMID 28131823 DOI: 10.1016/J.Cels.2017.01.002  0.8
2017 Khurana V, Peng J, Chung CY, Auluck PK, Fanning S, Tardiff DF, Bartels T, Koeva M, Eichhorn SW, Benyamini H, Lou Y, Nutter-Upham A, Baru V, Freyzon Y, Tuncbag N, et al. Genome-Scale Networks Link Neurodegenerative Disease Genes to α-Synuclein through Specific Molecular Pathways. Cell Systems. PMID 28131822 DOI: 10.1016/J.Cels.2016.12.011  0.8
2015 Khurana V, Tardiff DF, Chung CY, Lindquist S. Toward stem cell-based phenotypic screens for neurodegenerative diseases. Nature Reviews. Neurology. 11: 339-50. PMID 25986505 DOI: 10.1038/Nrneurol.2015.79  1
2015 Sahni N, Yi S, Taipale M, Fuxman Bass JI, Coulombe-Huntington J, Yang F, Peng J, Weile J, Karras GI, Wang Y, Kovács IA, Kamburov A, Krykbaeva I, Lam MH, Tucker G, ... Khurana V, et al. Widespread macromolecular interaction perturbations in human genetic disorders. Cell. 161: 647-60. PMID 25910212 DOI: 10.1016/J.Cell.2015.04.013  1
2014 Tardiff DF, Khurana V, Chung CY, Lindquist S. From yeast to patient neurons and back again: powerful new discovery platform. Movement Disorders : Official Journal of the Movement Disorder Society. 29: 1231-40. PMID 25131316 DOI: 10.1002/Mds.25989  1
2013 Tardiff DF, Jui NT, Khurana V, Tambe MA, Thompson ML, Chung CY, Kamadurai HB, Kim HT, Lancaster AK, Caldwell KA, Caldwell GA, Rochet JC, Buchwald SL, Lindquist S. Yeast reveal a "druggable" Rsp5/Nedd4 network that ameliorates α-synuclein toxicity in neurons. Science (New York, N.Y.). 342: 979-83. PMID 24158909 DOI: 10.1126/Science.1245321  0.8
2013 Chung CY, Khurana V, Auluck PK, Tardiff DF, Mazzulli JR, Soldner F, Baru V, Lou Y, Freyzon Y, Cho S, Mungenast AE, Muffat J, Mitalipova M, Pluth MD, Jui NT, et al. Identification and rescue of α-synuclein toxicity in Parkinson patient-derived neurons. Science (New York, N.Y.). 342: 983-7. PMID 24158904 DOI: 10.1126/Science.1245296  0.8
2013 Ding H, Dhima K, Lockhart KC, Locascio JJ, Hoesing AN, Duong K, Trisini-Lipsanopoulos A, Hayes MT, Sohur US, Wills AM, Mollenhauer B, Flaherty AW, Hung AY, Mejia N, Khurana V, et al. Unrecognized vitamin D3 deficiency is common in Parkinson disease: Harvard Biomarker Study. Neurology. 81: 1531-7. PMID 24068787 DOI: 10.1212/Wnl.0B013E3182A95818  1
2012 Khurana V, Merlo P, DuBoff B, Fulga TA, Sharp KA, Campbell SD, Götz J, Feany MB. A neuroprotective role for the DNA damage checkpoint in tauopathy. Aging Cell. 11: 360-2. PMID 22181010 DOI: 10.1111/J.1474-9726.2011.00778.X  1
2011 Soldner F, Laganière J, Cheng AW, Hockemeyer D, Gao Q, Alagappan R, Khurana V, Golbe LI, Myers RH, Lindquist S, Zhang L, Guschin D, Fong LK, Vu BJ, Meng X, et al. Generation of isogenic pluripotent stem cells differing exclusively at two early onset Parkinson point mutations. Cell. 146: 318-31. PMID 21757228 DOI: 10.1016/J.Cell.2011.06.019  1
2010 Khurana V, Elson-Schwab I, Fulga TA, Sharp KA, Loewen CA, Mulkearns E, Tyynelä J, Scherzer CR, Feany MB. Lysosomal dysfunction promotes cleavage and neurotoxicity of tau in vivo. Plos Genetics. 6: e1001026. PMID 20664788 DOI: 10.1371/Journal.Pgen.1001026  1
2010 Khurana V, Lindquist S. Modelling neurodegeneration in Saccharomyces cerevisiae: why cook with baker's yeast? Nature Reviews. Neuroscience. 11: 436-49. PMID 20424620 DOI: 10.1038/Nrn2809  1
2009 Atwood C, Brewer G, Herrup K, Kim D, Khurana V, Lamb B, Langley B, Leitner M, Muresan V, Neve R, Park K, Patzke H, Strobel G, Tsai LH, Yankner B. Alzheimer research forum live discussion: Meet new players, histone deacetylase and sirtuin - Will they help the cell cycle, DNA repair, and gene expression break into alzheimerology's major league? Journal of Alzheimer's Disease. 17: 233-238. PMID 19433902 DOI: 10.3233/Jad-2009-1084  1
2008 Khurana V. Modeling Tauopathy in the fruit fly Drosophila melanogaster. Journal of Alzheimer's Disease : Jad. 15: 541-53. PMID 19096155 DOI: 10.3233/Jad-2008-15403  1
2008 Sheth A, Khurana R, Khurana V. Potential liver damage associated with over-the-counter vitamin supplements. Journal of the American Dietetic Association. 108: 1536-7. PMID 18755329 DOI: 10.1016/j.jada.2008.06.443  0.36
2008 Khurana V, Caldito G, Ankem M. Statins might reduce risk of renal cell carcinoma in humans: case-control study of 500,000 veterans. Urology. 71: 118-22. PMID 18242378 DOI: 10.1016/j.urology.2007.08.039  0.36
2008 Sheth A, Train P, Kochhar R, Arbour GT, Khurana V. Para-aortic retained bullet causing aortic thrombosis: a case report. The Journal of Trauma. 64: 1625-7. PMID 17429321 DOI: 10.1097/01.ta.0000195493.00091.b0  0.36
2007 Khurana V, Bejjanki HR, Caldito G, Owens MW. Statins reduce the risk of lung cancer in humans: a large case-control study of US veterans. Chest. 131: 1282-8. PMID 17494779 DOI: 10.1378/chest.06-0931  0.36
2007 Khurana V, Sheth A, Caldito G, Barkin JS. Statins reduce the risk of pancreatic cancer in humans: a case-control study of half a million veterans. Pancreas. 34: 260-5. PMID 17312467 DOI: 10.1097/MPA.0b013e318030e963  0.36
2007 Fulga TA, Elson-Schwab I, Khurana V, Steinhilb ML, Spires TL, Hyman BT, Feany MB. Abnormal bundling and accumulation of F-actin mediates tau-induced neuronal degeneration in vivo. Nature Cell Biology. 9: 139-48. PMID 17187063 DOI: 10.1038/Ncb1528  1
2007 Khurana V, Feany MB. Connecting cell-cycle activation to neurodegeneration in Drosophila. Biochimica Et Biophysica Acta. 1772: 446-56. PMID 17141486 DOI: 10.1016/J.Bbadis.2006.10.007  1
2006 Gavin BA, Dolph MJ, Deleault NR, Geoghegan JC, Khurana V, Feany MB, Dolph PJ, Supattapone S. Accelerated accumulation of misfolded prion protein and spongiform degeneration in a Drosophila model of Gerstmann-Sträussler-Scheinker syndrome. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 12408-14. PMID 17135402 DOI: 10.1523/Jneurosci.3372-06.2006  1
2006 Khurana V. Tandem utilization of a hemostatic clip and a banding device in the esophagus: a novel hemostatic technique. Gastrointestinal Endoscopy. 63: 517-9. PMID 16500414 DOI: 10.1016/j.gie.2005.09.038  0.36
2006 Khurana V, Lu Y, Steinhilb ML, Oldham S, Shulman JM, Feany MB. TOR-mediated cell-cycle activation causes neurodegeneration in a Drosophila tauopathy model. Current Biology : Cb. 16: 230-41. PMID 16461276 DOI: 10.1016/J.Cub.2005.12.042  1
2005 Khurana V, Fulga TA, Feany MB. Senseless makes sense for spinocerebellar ataxia-1. Nature Neuroscience. 8: 1422-4. PMID 16251977 DOI: 10.1038/Nn1105-1422  1
2005 Khurana V, Singh T. Percutaneous endoscopic gastrostomy site metastasis in esophageal cancer. Gastrointestinal Endoscopy. 62: 612. PMID 16185981 DOI: 10.1016/S0016-5107(05)01642-1  0.36
2005 Abou-Assi SG, Khurana V, Schubert ML. Gastric and Postpyloric Total Enteral Nutrition. Current Treatment Options in Gastroenterology. 8: 145-152. PMID 15769436  0.36
2004 Jaganmohan S, Khurana V, Nopajaroonsri C. Squamous cell carcinoma of the penis presenting as a sterile inguinal abscess. The Journal of Urology. 172: 1877. PMID 15540742 DOI: 10.1097/01.ju.0000142720.74312.6e  0.36
2004 Khurana V, Dala R, Barkin JS. Small bowel cavernous hemangioma. Gastrointestinal Endoscopy. 60: 96. PMID 15229433 DOI: 10.1016/S0016-5107(04)01292-1  0.36
2003 Khurana V, Singh T. Gastric mucosal fibrosis: a novel explanation for dyspepsia. Medical Hypotheses. 61: 513-6. PMID 14592778 DOI: 10.1016/S0306-9877(03)00203-2  0.36
2003 Montijo IJ, Khurana V, Alazmi WM, Order SE, Barkin JS. Vascular pancreatic gastric fistula: a complication of colloidal 32P injection for nonresectable pancreatic cancer. Digestive Diseases and Sciences. 48: 1758-9. PMID 14560996 DOI: 10.1023/A:1025447128887  0.36
2001 Khurana V, Nehme O, Khurana R, Barkin JS. Urinary retention secondary to detrusor muscle hypofunction after botulinum toxin injection for achalasia. The American Journal of Gastroenterology. 96: 3211-2. PMID 11721783 DOI: 10.1111/j.1572-0241.2001.05290.x  0.36
2001 Khurana V, Barkin JS. Pancreatitis induced by environmental toxins. Pancreas. 22: 102-5. PMID 11138962 DOI: 10.1097/00006676-200101000-00019  0.36
2000 Khurana V, Stollman N, Rogers AI. Colorectal cancer: predicting prognosis for patients and probands using immunohistochemistry. The American Journal of Gastroenterology. 95: 2981-2. PMID 11051382  0.36
2000 Khurana V, Stollman N, Rogers AI. Colorectal cancer: predicting prognosis for patients and probands using immunohistochemistry. The American Journal of Gastroenterology. 95: 2119-20. PMID 10950070  0.36
1999 Khurana V, Bradley TP. Lead poisoning from a retained bullet: a case report and review. Journal of the Association For Academic Minority Physicians : the Official Publication of the Association For Academic Minority Physicians. 10: 48-9. PMID 10826009  0.36
1999 Khurana V, de la Fuente M, Bradley TP. Hypertensive crisis secondary to phenylpropanolamine interacting with triple-drug therapy for HIV prophylaxis. The American Journal of Medicine. 106: 118-9. PMID 10320127 DOI: 10.1016/S0002-9343(98)00370-2  0.36
1998 Khurana V, Bradley TP. Adult-onset Still's disease associated with G6PD deficiency: a case report and literature review. Journal of the Association For Academic Minority Physicians : the Official Publication of the Association For Academic Minority Physicians. 9: 56-8. PMID 9747060  0.36
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