| Year |
Citation |
Score |
| 2019 |
Goldman A, Smalley JL, Mistry M, Krenzlin H, Zhang H, Dhawan A, Caldarone B, Moss SJ, Silbersweig DA, Lawler SE, Braun IM. A computationally inspired in-vivo approach identifies a link between amygdalar transcriptional heterogeneity, socialization and anxiety. Translational Psychiatry. 9: 336. PMID 31819040 DOI: 10.1038/S41398-019-0677-1 |
0.308 |
|
| 2019 |
Liu B, Hinshaw RG, Le KX, Park MA, Wang S, Belanger AP, Dubey S, Frost JL, Shi Q, Holton P, Trojanczyk L, Reiser V, Jones PA, Trigg W, Di Carli MF, ... ... Caldarone BJ, et al. Space-like Fe irradiation manifests mild, early sex-specific behavioral and neuropathological changes in wildtype and Alzheimer's-like transgenic mice. Scientific Reports. 9: 12118. PMID 31431669 DOI: 10.1038/S41598-019-48615-1 |
0.375 |
|
| 2019 |
Albayram O, MacIver B, Mathai J, Verstegen A, Baxley S, Qiu C, Bell C, Caldarone BJ, Zhou XZ, Lu KP, Zeidel M. Traumatic Brain Injury-related voiding dysfunction in mice is caused by damage to rostral pathways, altering inputs to the reflex pathways. Scientific Reports. 9: 8646. PMID 31201348 DOI: 10.1038/S41598-019-45234-8 |
0.349 |
|
| 2017 |
Lanser AJ, Rezende RM, Rubino S, Lorello PJ, Donnelly DJ, Xu H, Lau LA, Dulla CG, Caldarone BJ, Robson SC, Weiner HL. Disruption of the ATP/Adenosine Balance in CD39-/- Mice is Associated with Handling-Induced Seizures. Immunology. PMID 28742222 DOI: 10.1111/Imm.12798 |
0.306 |
|
| 2017 |
Shi Q, Chowdhury S, Ma R, Le KX, Hong S, Caldarone BJ, Stevens B, Lemere CA. Complement C3 deficiency protects against neurodegeneration in aged plaque-rich APP/PS1 mice. Science Translational Medicine. 9. PMID 28566429 DOI: 10.1126/Scitranslmed.Aaf6295 |
0.39 |
|
| 2016 |
Rennekamp AJ, Huang XP, Wang Y, Patel S, Lorello PJ, Cade L, Gonzales AP, Yeh JJ, Caldarone BJ, Roth BL, Kokel D, Peterson RT. σ1 receptor ligands control a switch between passive and active threat responses. Nature Chemical Biology. PMID 27239788 DOI: 10.1038/Nchembio.2089 |
0.313 |
|
| 2016 |
Onajole OK, Vallerini GP, Eaton JB, Lukas RJ, Brunner D, Caldarone BJ, Kozikowski AP. Synthesis and Behavioral Studies of Chiral Cyclopropanes as Selective α4β2-Nicotinic Acetylcholine Receptor Partial Agonists Exhibiting an Antidepressant Profile. Part III. Acs Chemical Neuroscience. PMID 27035276 DOI: 10.1021/Acschemneuro.6B00050 |
0.395 |
|
| 2016 |
Lemere C, Crehan H, Liu B, Kleinschmidt M, Rahfeld J, Fitzpatrick E, Caldarone B, Le K, Frost J, O'Nuallain B, Park M, DiCarli M, Reiser V, Trigg W, Lues I, et al. Phagocytic characterization and therapeutic efficacy of an anti-PyroGlutamate-3 Aβ IgG2a antibody in aged APP/PS1dE9 mice Neurobiology of Aging. 39: S12-S13. DOI: 10.1016/j.neurobiolaging.2016.01.062 |
0.323 |
|
| 2016 |
Shi Q, Liu B, Man Hung AS, Le KX, Caldarone B, Ghosh S, Watson R, Lemere CA. P3-108: Beneficial Effects of Anti-Inflammatory, RNS60, in Aged APPSWE/PS1DE9 Mice Alzheimer's & Dementia. 12: P860-P860. DOI: 10.1016/J.Jalz.2016.06.1766 |
0.321 |
|
| 2015 |
Frost JL, Liu B, Rahfeld JU, Kleinschmidt M, O'Nuallain B, Le KX, Lues I, Caldarone BJ, Schilling S, Demuth HU, Lemere CA. An anti-pyroglutamate-3 Aβ vaccine reduces plaques and improves cognition in APPswe/PS1ΔE9 mice. Neurobiology of Aging. PMID 26453001 DOI: 10.1016/j.neurobiolaging.2015.08.021 |
0.348 |
|
| 2015 |
Shi Q, Colodner KJ, Matousek SB, Merry K, Hong S, Kenison JE, Frost JL, Le KX, Li S, Dodart JC, Caldarone BJ, Stevens B, Lemere CA. Complement C3-Deficient Mice Fail to Display Age-Related Hippocampal Decline. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 13029-42. PMID 26400934 DOI: 10.1523/Jneurosci.1698-15.2015 |
0.39 |
|
| 2015 |
Mably AJ, Kanmert D, Mc Donald JM, Liu W, Caldarone BJ, Lemere CA, O'Nuallain B, Kosik KS, Walsh DM. Tau immunization: a cautionary tale? Neurobiology of Aging. 36: 1316-32. PMID 25619661 DOI: 10.1016/j.neurobiolaging.2014.11.022 |
0.335 |
|
| 2015 |
Caldarone BJ, Zachariou V, King SL. Rodent models of treatment-resistant depression. European Journal of Pharmacology. 753: 51-65. PMID 25460020 DOI: 10.1016/j.ejphar.2014.10.063 |
0.657 |
|
| 2014 |
Onajole OK, Eaton JB, Lukas RJ, Brunner D, Thiede L, Caldarone BJ, Kozikowski AP. Enantiopure Cyclopropane-Bearing Pyridyldiazabicyclo[3.3.0]octanes as Selective α4β2-nAChR Ligands. Acs Medicinal Chemistry Letters. 5: 1196-201. PMID 25408831 DOI: 10.1021/Ml500129K |
0.369 |
|
| 2014 |
Yu LF, Zhang HK, Caldarone BJ, Eaton JB, Lukas RJ, Kozikowski AP. Recent developments in novel antidepressants targeting α4β2-nicotinic acetylcholine receptors. Journal of Medicinal Chemistry. 57: 8204-23. PMID 24901260 DOI: 10.1021/Jm401937A |
0.417 |
|
| 2014 |
Lemere CA, Shi Q, Caldarone B, Chowdhury S, Ma R, Hong S, Stevens B. S4-02-03: COMPLEMENT IN ALZHEIMER'S DISEASE: LESSONS FROM C3-DEFICIENT MICE Alzheimer's & Dementia. 10: P240-P240. DOI: 10.1016/J.Jalz.2014.04.360 |
0.312 |
|
| 2013 |
Stratinaki M, Varidaki A, Mitsi V, Ghose S, Magida J, Dias C, Russo SJ, Vialou V, Caldarone BJ, Tamminga CA, Nestler EJ, Zachariou V. Regulator of G protein signaling 4 [corrected] is a crucial modulator of antidepressant drug action in depression and neuropathic pain models. Proceedings of the National Academy of Sciences of the United States of America. 110: 8254-9. PMID 23630294 DOI: 10.1073/Pnas.1214696110 |
0.634 |
|
| 2013 |
Stratinaki M, Varidaki A, Mitsi V, Ghose S, Magida J, Dias C, Russo SJ, Vialou V, Caldarone BJ, Tamminga CA, Nestler EJ, Zachariou V. Regulator of G protein signaling is a crucial modulator of antidepressant drug action in depression and neuropathic pain models(Proceedings of the National Academy of Sciences of the United States of America (2013) 110, 20 (8254-8259)) Proceedings of the National Academy of Sciences of the United States of America. 110: 11660. DOI: 10.1073/Pnas.1311399110 |
0.585 |
|
| 2013 |
Frost J, Kleinschmidt M, O'Nuallian B, Le KX, Caldarone B, Schilling S, Demuth H, Lemere C. Passive immunization against pyroglutamate-3 beta-amyloid decreases total plaque load in the absence of microhemorrhage and attenuates cognitive deficits in APP/PS1dE9 mice Alzheimers & Dementia. 9: 508. DOI: 10.1016/J.Jalz.2013.05.1062 |
0.363 |
|
| 2013 |
Shi Q, Caldarone B, Merry K, Hong S, McKinney PP, Frost J, Matousek S, Kenison J, Chowdhury S, Le KX, Stevens B, Lemere C. P2-375: Behavioral changes associated with complement C3-deficiency in aged Alzheimer's disease-like Tg mice Alzheimer's & Dementia. 9: P496-P497. DOI: 10.1016/J.Jalz.2013.05.1024 |
0.332 |
|
| 2013 |
Lemere C, Shi Q, Colodner K, Matousek S, Merry K, Frost J, Kenison J, Chowdhury S, McKinney P, Caldarone B, Stevens B. O2-07-03: Complement C3-deficiency preserves hippocampal synapses and neurons with aging and improves learning and memory compared to WT mice Alzheimer's & Dementia. 9: P328-P328. DOI: 10.1016/J.Jalz.2013.04.173 |
0.343 |
|
| 2012 |
Zhang H, Tückmantel W, Eaton JB, Yuen PW, Yu LF, Bajjuri KM, Fedolak A, Wang D, Ghavami A, Caldarone B, Paterson NE, Lowe DA, Brunner D, Lukas RJ, Kozikowski AP. Chemistry and behavioral studies identify chiral cyclopropanes as selective α4β2-nicotinic acetylcholine receptor partial agonists exhibiting an antidepressant profile. Journal of Medicinal Chemistry. 55: 717-24. PMID 22171543 DOI: 10.1021/Jm201157C |
0.413 |
|
| 2012 |
Yu LF, Tückmantel W, Eaton JB, Caldarone B, Fedolak A, Hanania T, Brunner D, Lukas RJ, Kozikowski AP. Identification of novel α4β2-nicotinic acetylcholine receptor (nAChR) agonists based on an isoxazole ether scaffold that demonstrate antidepressant-like activity. Journal of Medicinal Chemistry. 55: 812-23. PMID 22148173 DOI: 10.1021/Jm201301H |
0.446 |
|
| 2011 |
Liu J, Yu LF, Eaton JB, Caldarone B, Cavino K, Ruiz C, Terry M, Fedolak A, Wang D, Ghavami A, Lowe DA, Brunner D, Lukas RJ, Kozikowski AP. Discovery of isoxazole analogues of sazetidine-A as selective α4β2-nicotinic acetylcholine receptor partial agonists for the treatment of depression. Journal of Medicinal Chemistry. 54: 7280-8. PMID 21905669 DOI: 10.1021/Jm200855B |
0.422 |
|
| 2011 |
Kozikowski AP, Gunosewoyo H, Guo S, Gaisina IN, Walter RL, Ketcherside A, McClung CA, Mesecar AD, Caldarone B. Identification of a glycogen synthase kinase-3β inhibitor that attenuates hyperactivity in CLOCK mutant mice. Chemmedchem. 6: 1593-602. PMID 21732538 DOI: 10.1002/Cmdc.201100188 |
0.352 |
|
| 2011 |
Caldarone BJ, Wang D, Paterson NE, Manzano M, Fedolak A, Cavino K, Kwan M, Hanania T, Chellappan SK, Kozikowski AP, Olivier B, Picciotto MR, Ghavami A. Dissociation between duration of action in the forced swim test in mice and nicotinic acetylcholine receptor occupancy with sazetidine, varenicline, and 5-I-A85380. Psychopharmacology. 217: 199-210. PMID 21487659 DOI: 10.1007/S00213-011-2271-Y |
0.64 |
|
| 2010 |
Caldarone BJ, Paterson NE, Zhou J, Brunner D, Kozikowski AP, Westphal KG, Korte-Bouws GA, Prins J, Korte SM, Olivier B, Ghavami A. The novel triple reuptake inhibitor JZAD-IV-22 exhibits an antidepressant pharmacological profile without locomotor stimulant or sensitization properties. The Journal of Pharmacology and Experimental Therapeutics. 335: 762-70. PMID 20864506 DOI: 10.1124/Jpet.110.174011 |
0.329 |
|
| 2010 |
Liu J, Eaton JB, Caldarone B, Lukas RJ, Kozikowski AP. Chemistry and pharmacological characterization of novel nitrogen analogues of AMOP-H-OH (Sazetidine-A, 6-[5-(azetidin-2-ylmethoxy)pyridin-3-yl]hex-5-yn-1-ol) as α4β2-nicotinic acetylcholine receptor-selective partial agonists. Journal of Medicinal Chemistry. 53: 6973-85. PMID 20822184 DOI: 10.1021/jm100765u |
0.384 |
|
| 2010 |
Paterson NE, Min W, Hackett A, Lowe D, Hanania T, Caldarone B, Ghavami A. The high-affinity nAChR partial agonists varenicline and sazetidine-A exhibit reinforcing properties in rats. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 34: 1455-64. PMID 20708056 DOI: 10.1016/j.pnpbp.2010.07.037 |
0.425 |
|
| 2010 |
Paterson NE, Fedolak A, Olivier B, Hanania T, Ghavami A, Caldarone B. Psychostimulant-like discriminative stimulus and locomotor sensitization properties of the wake-promoting agent modafinil in rodents. Pharmacology, Biochemistry, and Behavior. 95: 449-56. PMID 20346966 DOI: 10.1016/J.Pbb.2010.03.006 |
0.332 |
|
| 2009 |
Kozikowski AP, Eaton JB, Bajjuri KM, Chellappan SK, Chen Y, Karadi S, He R, Caldarone B, Manzano M, Yuen PW, Lukas RJ. Chemistry and pharmacology of nicotinic ligands based on 6-[5-(azetidin-2-ylmethoxy)pyridin-3-yl]hex-5-yn-1-ol (AMOP-H-OH) for possible use in depression. Chemmedchem. 4: 1279-91. PMID 19569163 DOI: 10.1002/Cmdc.200900079 |
0.441 |
|
| 2009 |
Traynor JR, Terzi D, Caldarone BJ, Zachariou V. RGS9-2: probing an intracellular modulator of behavior as a drug target. Trends in Pharmacological Sciences. 30: 105-11. PMID 19211160 DOI: 10.1016/j.tips.2008.11.006 |
0.617 |
|
| 2009 |
Caldarone B, Manzano M, Paterson N, Kozikowksi A, Olivier B, Ghavami A. Antidepressant-like activity of AMOP-H-OH (‘sazetidine-A’) in the forced swim test is mediated by high affinity nicotinic acetylcholine receptors Biochemical Pharmacology. 78: 921-922. DOI: 10.1016/j.bcp.2009.06.085 |
0.408 |
|
| 2008 |
Caldarone BJ, King SL, Picciotto MR. Sex differences in anxiety-like behavior and locomotor activity following chronic nicotine exposure in mice. Neuroscience Letters. 439: 187-91. PMID 18524488 DOI: 10.1016/j.neulet.2008.05.023 |
0.723 |
|
| 2007 |
Kozikowski AP, Gaisina IN, Yuan H, Petukhov PA, Blond SY, Fedolak A, Caldarone B, McGonigle P. Structure-based design leads to the identification of lithium mimetics that block mania-like effects in rodents. possible new GSK-3beta therapies for bipolar disorders. Journal of the American Chemical Society. 129: 8328-32. PMID 17552518 DOI: 10.1021/Ja068969W |
0.317 |
|
| 2007 |
Lynch WJ, Kiraly DD, Caldarone BJ, Picciotto MR, Taylor JR. Effect of cocaine self-administration on striatal PKA-regulated signaling in male and female rats. Psychopharmacology. 191: 263-71. PMID 17180335 DOI: 10.1007/s00213-006-0656-0 |
0.486 |
|
| 2006 |
Rabenstein RL, Caldarone BJ, Picciotto MR. The nicotinic antagonist mecamylamine has antidepressant-like effects in wild-type but not beta2- or alpha7-nicotinic acetylcholine receptor subunit knockout mice. Psychopharmacology. 189: 395-401. PMID 17016705 DOI: 10.1007/s00213-006-0568-z |
0.783 |
|
| 2006 |
Miwa JM, Stevens TR, King SL, Caldarone BJ, Ibanez-Tallon I, Xiao C, Fitzsimonds RM, Pavlides C, Lester HA, Picciotto MR, Heintz N. The prototoxin lynx1 acts on nicotinic acetylcholine receptors to balance neuronal activity and survival in vivo. Neuron. 51: 587-600. PMID 16950157 DOI: 10.1016/J.Neuron.2006.07.025 |
0.811 |
|
| 2005 |
Rabenstein RL, Addy NA, Caldarone BJ, Asaka Y, Gruenbaum LM, Peters LL, Gilligan DM, Fitzsimonds RM, Picciotto MR. Impaired synaptic plasticity and learning in mice lacking beta-adducin, an actin-regulating protein. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 2138-45. PMID 15728854 DOI: 10.1523/JNEUROSCI.3530-04.2005 |
0.707 |
|
| 2004 |
Caldarone BJ, Harrist A, Cleary MA, Beech RD, King SL, Picciotto MR. High-affinity nicotinic acetylcholine receptors are required for antidepressant effects of amitriptyline on behavior and hippocampal cell proliferation. Biological Psychiatry. 56: 657-64. PMID 15522249 DOI: 10.1016/J.Biopsych.2004.08.010 |
0.79 |
|
| 2004 |
Harrist A, Beech RD, King SL, Zanardi A, Cleary MA, Caldarone BJ, Eisch A, Zoli M, Picciotto MR. Alteration of hippocampal cell proliferation in mice lacking the beta 2 subunit of the neuronal nicotinic acetylcholine receptor. Synapse (New York, N.Y.). 54: 200-6. PMID 15472930 DOI: 10.1002/Syn.20081 |
0.765 |
|
| 2004 |
King SL, Caldarone BJ, Picciotto MR. Beta2-subunit-containing nicotinic acetylcholine receptors are critical for dopamine-dependent locomotor activation following repeated nicotine administration. Neuropharmacology. 47: 132-9. PMID 15464132 DOI: 10.1016/j.neuropharm.2004.06.024 |
0.737 |
|
| 2003 |
Caldarone BJ, Karthigeyan K, Harrist A, Hunsberger JG, Wittmack E, King SL, Jatlow P, Picciotto MR. Sex differences in response to oral amitriptyline in three animal models of depression in C57BL/6J mice. Psychopharmacology. 170: 94-101. PMID 12879206 DOI: 10.1007/S00213-003-1518-7 |
0.692 |
|
| 2003 |
King SL, Marks MJ, Grady SR, Caldarone BJ, Koren AO, Mukhin AG, Collins AC, Picciotto MR. Conditional expression in corticothalamic efferents reveals a developmental role for nicotinic acetylcholine receptors in modulation of passive avoidance behavior. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 3837-43. PMID 12736354 DOI: 10.1523/Jneurosci.23-09-03837.2003 |
0.754 |
|
| 2002 |
Picciotto MR, Brunzell DH, Caldarone BJ. Effect of nicotine and nicotinic receptors on anxiety and depression. Neuroreport. 13: 1097-106. PMID 12151749 DOI: 10.1097/00001756-200207020-00006 |
0.769 |
|
| 2002 |
Di Paolo G, Sankaranarayanan S, Wenk MR, Daniell L, Perucco E, Caldarone BJ, Flavell R, Picciotto MR, Ryan TA, Cremona O, De Camilli P. Decreased synaptic vesicle recycling efficiency and cognitive deficits in amphiphysin 1 knockout mice. Neuron. 33: 789-804. PMID 11879655 DOI: 10.1016/S0896-6273(02)00601-3 |
0.565 |
|
| 2001 |
Picciotto MR, Caldarone BJ, Brunzell DH, Zachariou V, Stevens TR, King SL. Neuronal nicotinic acetylcholine receptor subunit knockout mice: physiological and behavioral phenotypes and possible clinical implications. Pharmacology & Therapeutics. 92: 89-108. PMID 11916531 DOI: 10.1016/S0163-7258(01)00161-9 |
0.775 |
|
| 2001 |
Zachariou V, Caldarone BJ, Weathers-Lowin A, George TP, Elsworth JD, Roth RH, Changeux JP, Picciotto MR. Nicotine receptor inactivation decreases sensitivity to cocaine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 24: 576-89. PMID 11282258 DOI: 10.1016/S0893-133X(00)00224-4 |
0.741 |
|
| 2000 |
Bolivar VJ, Caldarone BJ, Reilly AA, Flaherty L. Habituation of activity in an open field: A survey of inbred strains and F1 hybrids. Behavior Genetics. 30: 285-93. PMID 11206083 DOI: 10.1023/A:1026545316455 |
0.506 |
|
| 2000 |
Caldarone BJ, Duman CH, Picciotto MR. Fear conditioning and latent inhibition in mice lacking the high affinity subclass of nicotinic acetylcholine receptors in the brain. Neuropharmacology. 39: 2779-84. PMID 11044747 DOI: 10.1016/S0028-3908(00)00137-4 |
0.681 |
|
| 2000 |
Caldarone BJ, George TP, Zachariou V, Picciotto MR. Gender differences in learned helplessness behavior are influenced by genetic background. Pharmacology, Biochemistry, and Behavior. 66: 811-7. PMID 10973520 DOI: 10.1016/S0091-3057(00)00271-9 |
0.705 |
|
| 2000 |
Picciotto MR, Caldarone BJ, King SL, Zachariou V. Nicotinic receptors in the brain. Links between molecular biology and behavior. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 22: 451-65. PMID 10731620 DOI: 10.1016/S0893-133X(99)00146-3 |
0.781 |
|
| 1997 |
Caldarone B, Saavedra C, Tartaglia K, Wehner JM, Dudek BC, Flaherty L. Quantitative trait loci analysis affecting contextual conditioning in mice. Nature Genetics. 17: 335-7. PMID 9354801 DOI: 10.1038/Ng1197-335 |
0.517 |
|
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