| Year |
Citation |
Score |
| 2021 |
Urrutia G, de Assuncao TM, Mathison AJ, Salmonson A, Kerketta R, Zeighami A, Stodola TJ, Adsay V, Pehlivanoglu B, Dwinell MB, Zimmermann MT, Iovanna JL, Urrutia R, Lomberk G. Inactivation of the Euchromatic Histone-Lysine -Methyltransferase 2 Pathway in Pancreatic Epithelial Cells Antagonizes Cancer Initiation and Pancreatitis-Associated Promotion by Altering Growth and Immune Gene Expression Networks. Frontiers in Cell and Developmental Biology. 9: 681153. PMID 34249932 DOI: 10.3389/fcell.2021.681153 |
0.338 |
|
| 2020 |
Lan W, Santofimia-Castaño P, Swayden M, Xia Y, Zhou Z, Audebert S, Camoin L, Huang C, Peng L, Jiménez-Alesanco A, Velázquez-Campoy A, Abian O, Lomberk G, Urrutia R, Rizzuti B, et al. ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents. Jci Insight. PMID 32780723 DOI: 10.1172/Jci.Insight.138117 |
0.349 |
|
| 2020 |
Che M, Kweon SM, Teo JL, Yuan YC, Melstrom LG, Waldron RT, Lugea A, Urrutia RA, Pandol SJ, Lai KKY. Targeting the CBP/β-Catenin Interaction to Suppress Activation of Cancer-Promoting Pancreatic Stellate Cells. Cancers. 12. PMID 32516943 DOI: 10.3390/Cancers12061476 |
0.384 |
|
| 2020 |
Yang C, Siebert JR, Burns R, Zheng Y, Mei A, Bonacci B, Wang D, Urrutia RA, Riese MJ, Rao S, Carlson KS, Thakar MS, Malarkannan S. Single-cell transcriptome reveals the novel role of T-bet in suppressing the immature NK gene signature. Elife. 9. PMID 32406817 DOI: 10.7554/Elife.51339 |
0.334 |
|
| 2020 |
Muraki T, Reid MD, Pehlivanoglu B, Gonzalez RS, Sekhar A, Memis B, Xue Y, Cheng J, Jang KT, Mittal P, Cardona K, Kooby DA, Maithel S, Sarmiento JM, El-Rayes B, ... ... Urrutia RA, et al. Variant anatomy of the biliary system as a cause of pancreatic and peri-ampullary cancers. Hpb : the Official Journal of the International Hepato Pancreato Biliary Association. PMID 32336556 DOI: 10.1016/J.Hpb.2020.03.014 |
0.313 |
|
| 2020 |
Yamazaki Y, Urrutia R, Franco LM, Giliani S, Zhang K, Alazami AM, Dobbs AK, Masneri S, Joshi A, Otaizo-Carrasquero F, Myers TG, Ganesan S, Bondioni MP, Ho ML, Marks C, et al. PAX1 is essential for development and function of the human thymus. Science Immunology. 5. PMID 32111619 DOI: 10.1126/Sciimmunol.Aax1036 |
0.354 |
|
| 2020 |
Mathison A, Milech De Assuncao T, Dsouza NR, Williams M, Zimmermann MT, Urrutia R, Lomberk G. Discovery, expression, cellular localization, and molecular properties of a novel, alternative spliced HP1γ isoform, lacking the chromoshadow domain. Plos One. 15: e0217452. PMID 32027651 DOI: 10.1371/Journal.Pone.0217452 |
0.327 |
|
| 2020 |
Yang C, Siebert JR, Burns R, Zheng Y, Mei A, Bonacci B, Wang D, Urrutia RA, Riese MJ, Rao S, Carlson K, Thakar MS, Malarkannan S. Author response: Single-cell transcriptome reveals the novel role of T-bet in suppressing the immature NK gene signature Elife. DOI: 10.7554/Elife.51339.Sa2 |
0.31 |
|
| 2020 |
Urrutia G, Dusetti N, Iovanna J, Urrutia R, Lomberk G. Gemcitabine Exposure Induces Epigenomic Remodeling in Pancreatic Cancer Cells during Resistance Development The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.05341 |
0.318 |
|
| 2019 |
Urrutia G, Salmonson A, Toro-Zapata J, de Assuncao TM, Mathison A, Dusetti N, Iovanna J, Urrutia R, Lomberk G. Combined Targeting of G9a and Checkpoint Kinase 1 Synergistically Inhibits Pancreatic Cancer Cell Growth by Replication Fork Collapse. Molecular Cancer Research : McR. 18: 448-462. PMID 31822519 DOI: 10.1158/1541-7786.Mcr-19-0490 |
0.346 |
|
| 2019 |
Santofimia-Castaño P, Xia Y, Peng L, Velázquez-Campoy A, Abián O, Lan W, Lomberk G, Urrutia R, Rizzuti B, Soubeyran P, Neira JL, Iovanna J. Targeting the Stress-Induced Protein NUPR1 to Treat Pancreatic Adenocarcinoma. Cells. 8. PMID 31744261 DOI: 10.3390/Cells8111453 |
0.376 |
|
| 2019 |
He C, Danes JM, Hart PC, Zhu Y, Huang Y, de Abreu AL, O'Brien J, Mathison AJ, Tang B, Frasor JM, Wakefield LM, Ganini D, Stauder E, Zielonka J, Gantner BN, ... Urrutia RA, et al. SOD2 acetylation on lysine 68 promotes stem cell reprogramming in breast cancer. Proceedings of the National Academy of Sciences of the United States of America. PMID 31591207 DOI: 10.1073/Pnas.1902308116 |
0.355 |
|
| 2019 |
Lomberk G, Dusetti N, Iovanna J, Urrutia R. Emerging epigenomic landscapes of pancreatic cancer in the era of precision medicine Nature Communications. 10: 3875. PMID 31462645 DOI: 10.1038/S41467-019-11812-7 |
0.333 |
|
| 2019 |
Han EH, Singh P, Lee IK, Urrutia R, Chi YI. ErbB3-binding protein 1 (EBP1) represses HNF4α-mediated transcription and insulin secretion in pancreatic β-cells. The Journal of Biological Chemistry. PMID 31362984 DOI: 10.1074/Jbc.Ra119.009558 |
0.39 |
|
| 2019 |
Zimmermann MT, Williams MM, Klee EW, Lomberk GA, Urrutia R. Modeling Post-Translational Modifications and Cancer-Associated Mutations that Impact the Heterochromatin Protein 1α-Importin Α Heterodimers. Proteins. PMID 31152607 DOI: 10.1002/Prot.25752 |
0.355 |
|
| 2019 |
Ligresti G, Caporarello N, Meridew JA, Jones DL, Tan Q, Choi KM, Haak AJ, Aravamudhan A, Roden AC, Prakash YS, Lomberk G, Urrutia RA, Tschumperlin DJ. CBX5/G9a/H3K9me-mediated gene repression is essential to fibroblast activation during lung fibrosis. Jci Insight. 5. PMID 31095524 DOI: 10.1172/Jci.Insight.127111 |
0.322 |
|
| 2019 |
Bamidele AO, Svingen PA, Sagstetter MR, Sarmento OF, Gonzalez M, Braga Neto MB, Kugathasan S, Lomberk G, Urrutia RA, Faubion WA. Disruption of FOXP3-EZH2 Interaction Represents a Pathobiological Mechanism in Intestinal Inflammation. Cellular and Molecular Gastroenterology and Hepatology. 7: 55-71. PMID 30510991 DOI: 10.1016/J.Jcmgh.2018.08.009 |
0.358 |
|
| 2019 |
Abrudan J, Tsai S, Demos W, Zimmermann MT, Tschannen M, Geurts J, Mathison A, Lomberk G, Evans D, Urrutia R. Abstract 4163: Genomic variation in PDAC-predisposing genes identified using the MCW germline exome panel Cancer Research. 79: 4163-4163. DOI: 10.1158/1538-7445.Sabcs18-4163 |
0.334 |
|
| 2018 |
Santofimia-Castaño P, Lan W, Bintz J, Gayet O, Carrier A, Lomberk G, Neira JL, González A, Urrutia R, Soubeyran P, Iovanna J. Inactivation of NUPR1 promotes cell death by coupling ER-stress responses with necrosis. Scientific Reports. 8: 16999. PMID 30451898 DOI: 10.1038/S41598-018-35020-3 |
0.341 |
|
| 2018 |
Stoltz KP, Jondle CN, Pulakanti K, Sylvester PA, Urrutia R, Rao S, Tarakanova VL. Tumor suppressor Interferon Regulatory Factor 1 selectively blocks expression of endogenous retrovirus. Virology. 526: 52-60. PMID 30342302 DOI: 10.1016/J.Virol.2018.10.003 |
0.351 |
|
| 2018 |
Seo S, Mathison A, Grzenda A, Podratz J, Calvo E, Brimijoin S, Windebank A, Iovanna J, Lomberk G, Urrutia R. Mechanisms Underlying the Regulation of HP1γ by the NGF-PKA Signaling Pathway. Scientific Reports. 8: 15077. PMID 30305677 DOI: 10.1038/S41598-018-33475-Y |
0.764 |
|
| 2018 |
Lomberk G, Blum Y, Nicolle R, Nair A, Gaonkar KS, Marisa L, Mathison A, Sun Z, Yan H, Elarouci N, Armenoult L, Ayadi M, Ordog T, Lee JH, Oliver G, ... ... Urrutia R, et al. Distinct epigenetic landscapes underlie the pathobiology of pancreatic cancer subtypes. Nature Communications. 9: 1978. PMID 29773832 DOI: 10.1038/S41467-018-04383-6 |
0.367 |
|
| 2018 |
Dou C, Liu Z, Tu K, Zhang H, Chen C, Yaqoob U, Wang Y, Wen J, van Deursen J, Sicard D, Tschumperlin D, Zou H, Huang WC, Urrutia R, Shah VH, et al. P300 Acetyltransferase Mediates Stiffness-Induced Activation of Hepatic Stellate Cells Into Tumor-promoting Myofibroblasts. Gastroenterology. PMID 29454793 DOI: 10.1053/J.Gastro.2018.02.015 |
0.346 |
|
| 2017 |
Drinane MC, Yaqoob U, Yu H, Luo F, Greuter T, Arab JP, Kostallari E, Verma VK, Maiers J, De Assuncao TM, Simons M, Mukhopadhyay D, Kisseleva T, Brenner DA, Urrutia R, et al. Synectin promotes fibrogenesis by regulating PDGFR isoforms through distinct mechanisms. Jci Insight. 2. PMID 29263300 DOI: 10.1172/Jci.Insight.92821 |
0.387 |
|
| 2017 |
Nicolle R, Blum Y, Marisa L, Loncle C, Gayet O, Moutardier V, Turrini O, Giovannini M, Bian B, Bigonnet M, Rubis M, Elarouci N, Armenoult L, Ayadi M, Duconseil P, ... ... Urrutia R, et al. Pancreatic Adenocarcinoma Therapeutic Targets Revealed by Tumor-Stroma Cross-Talk Analyses in Patient-Derived Xenografts. Cell Reports. 21: 2458-2470. PMID 29186684 DOI: 10.1016/J.Celrep.2017.11.003 |
0.352 |
|
| 2017 |
Santofimia-Castaño P, Rizzuti B, Pey ÁL, Soubeyran P, Vidal M, Urrutia R, Iovanna JL, Neira JL. Intrinsically disordered chromatin protein NUPR1 binds to the C-terminal region of Polycomb RING1B. Proceedings of the National Academy of Sciences of the United States of America. 114: 201619932. PMID 28720707 DOI: 10.1073/Pnas.1619932114 |
0.34 |
|
| 2017 |
Blackburn PR, Williams M, Cousin MA, Boczek NJ, Beek GJ, Lomberk GA, Urrutia RA, Babovic-Vuksanovic D, Klee EW. A novel de novo frameshift deletion in EHMT1 in a patient with Kleefstra Syndrome results in decreased H3K9 dimethylation. Molecular Genetics & Genomic Medicine. 5: 141-146. PMID 28361100 DOI: 10.1002/Mgg3.268 |
0.31 |
|
| 2017 |
Higgins EM, Bos JM, Mason-Suares H, Tester DJ, Ackerman JP, MacRae CA, Sol-Church K, Gripp KW, Urrutia R, Ackerman MJ. Elucidation of MRAS-mediated Noonan syndrome with cardiac hypertrophy. Jci Insight. 2: e91225. PMID 28289718 DOI: 10.1172/Jci.Insight.91225 |
0.301 |
|
| 2017 |
Bian B, Bigonnet M, Gayet O, Loncle C, Maignan A, Gilabert M, Moutardier V, Garcia S, Turrini O, Delpero JR, Giovannini M, Grandval P, Gasmi M, Ouaissi M, Secq V, ... ... Urrutia R, et al. Gene expression profiling of patient-derived pancreatic cancer xenografts predicts sensitivity to the BET bromodomain inhibitor JQ1: implications for individualized medicine efforts. Embo Molecular Medicine. PMID 28275007 DOI: 10.15252/Emmm.201606975 |
0.386 |
|
| 2017 |
Blackburn PR, Tischer A, Zimmermann MT, Kemppainen JL, Sastry S, Knight Johnson AE, Cousin MA, Boczek NJ, Oliver G, Misra VK, Gavrilova RH, Lomberk GA, Auton M, Urrutia RA, Klee EW. A Novel Kleefstra Syndrome Associated Variant that Affects the Conserved TPLX Motif within the Ankyrin Repeat of EHMT1 Leads to Abnormal Protein Folding. The Journal of Biological Chemistry. PMID 28057753 DOI: 10.1074/Jbc.M116.770545 |
0.302 |
|
| 2017 |
Nicolle R, Blum Y, Marisa L, Loncle C, Gayet O, Moutardier V, Turrini O, Giovannini M, Bian B, Bigonnet M, Rubis M, Elarouci N, Armenoult L, Ayadi M, Duconseil P, ... ... Urrutia R, et al. Abstract 4396: Multiomics assessment of the cancer and stromal compartments of patient-derived pancreatic xenografts reveals clinically-relevant subtypes and novel targeted therapies Cancer Research. 77: 4396-4396. DOI: 10.1158/1538-7445.Am2017-4396 |
0.369 |
|
| 2017 |
Mathison A, Salmonson A, Paradise B, Missfeldt M, Iovanna J, Billadeau D, Urrutia R, Lomberk G. Abstract 1391: The epigenetic regulator, G9a, is a KRAS-inducible protein and its inactivation inhibits PanIN formation by this oncogene Cancer Research. 77: 1391-1391. DOI: 10.1158/1538-7445.Am2017-1391 |
0.403 |
|
| 2017 |
Sarmento OF, Svingen P, Sun Z, Nair A, Sagstetter M, Gonzalez M, Bamidele AO, Friton J, Urrutia R, Faubion W. HIF1Α Regulates FOXP3 Epigenetic Complexes Implicated in IBD Gastroenterology. 152. DOI: 10.1016/S0016-5085(17)30609-1 |
0.323 |
|
| 2016 |
Jalan-Sakrikar N, De Assuncao TM, Lu J, Almada LL, Lomberk G, Fernandez-Zapico ME, Urrutia R, Huebert RC. Hedgehog Signaling Overcomes an EZH2-Dependent Epigenetic Barrier to Promote Cholangiocyte Expansion. Plos One. 11: e0168266. PMID 27936185 DOI: 10.1371/Journal.Pone.0168266 |
0.352 |
|
| 2016 |
Sarmento OF, Svingen PA, Xiong Y, Sun Z, Bamidele AO, Mathison AJ, Smyrk TC, Nair AA, Gonzalez MM, Sagstetter MR, Baheti S, McGovern DP, Friton JJ, Papadakis KA, Gautam G, ... ... Urrutia RA, et al. The Role of the Histone Methyltransferase Enhancer of Zeste Homolog 2 (EZH2) in the Pathobiological Mechanisms Underlying Inflammatory Bowel Disease (IBD). The Journal of Biological Chemistry. PMID 27909059 DOI: 10.1074/Jbc.M116.749663 |
0.342 |
|
| 2016 |
Wang J, Galvao J, Beach KM, Luo W, Urrutia RA, Goldberg JL, Otteson DC. Novel roles and mechanism for Krüppel-like factor 16 (KLF16) regulation of neurite outgrowth and ephrin receptor A5 (EphA5) expression in retinal ganglion cells. The Journal of Biological Chemistry. 291: 21422. PMID 27825077 DOI: 10.1074/Jbc.A116.732339 |
0.306 |
|
| 2016 |
Saha S, Xiong X, Chakraborty PK, Shameer K, Arvizo RR, Kudgus RA, Dwivedi SK, Hossen MN, Gillies EM, Robertson JD, Dudley JT, Urrutia RA, Postier RG, Bhattacharya R, Mukherjee P. Gold Nanoparticle Reprograms Pancreatic Tumor Microenvironment and Inhibits Tumor Growth. Acs Nano. PMID 27758098 DOI: 10.1021/Acsnano.6B02231 |
0.351 |
|
| 2016 |
Loncle C, Molejon MI, Lac S, Tellechea JI, Lomberk G, Gramatica L, Zapico MFF, Dusetti N, Urrutia R, Iovanna JL. The pancreatitis-associated protein VMP1, a key regulator of inducible autophagy, promotes Kras(G12D)-mediated pancreatic cancer initiation. Cell Death and Disease. 7: 0. PMID 27415425 DOI: 10.1038/Cddis.2016.202 |
0.398 |
|
| 2016 |
Wang J, Galvao J, Beach KM, Luo W, Urrutia RA, Goldberg JL, Otteson DC. Novel Roles and Mechanism for Kruppel-like factor 16 (KLF16) Regulation of Neurite Outgrowth and Ephrin Receptor A5 (EphA5) Expression in Retinal Ganglion Cells. The Journal of Biological Chemistry. PMID 27402841 DOI: 10.1074/Jbc.M116.732339 |
0.394 |
|
| 2016 |
Lomberk GA, Iovanna J, Urrutia R. The promise of epigenomic therapeutics in pancreatic cancer Epigenomics. 8: 831-842. PMID 27337224 DOI: 10.2217/Epi-2015-0016 |
0.367 |
|
| 2016 |
Loncle C, Bonjoch L, Folch-Puy E, Lopez-Millan MB, Lac S, Molejon MI, Chuluyan E, Cordelier P, Dubus P, Lomberk G, Urrutia R, Closa D, Iovanna JL. REG3β Plays a Key Role in IL17RA Protumoral Effect—Response Cancer Research. 76: 2051-2051. PMID 26992425 DOI: 10.1158/0008-5472.Can-15-3355 |
0.321 |
|
| 2016 |
Sarmento O, Xiong Y, Sun Z, Svingen P, Bamidele A, Smyrk T, Nair A, Baheti S, McGovern D, Friton J, Papadakis K, Goel G, Xavier R, Urrutia R, Faubion W. O-015 YI Alterations in the FOXP3-EZH2 Pathway Associates with Increased Susceptibility to Colitis in Both Mice and Human. Inflammatory Bowel Diseases. 22: S5-S6. PMID 26849732 DOI: 10.1097/01.Mib.0000480101.02647.09 |
0.375 |
|
| 2016 |
Velez G, Lin M, Christensen T, Faubion WA, Lomberk G, Urrutia R. Evidence supporting a critical contribution of intrinsically disordered regions to the biochemical behavior of full-length human HP1γ. Journal of Molecular Modeling. 22: 12. PMID 26680990 DOI: 10.1007/S00894-015-2874-Z |
0.341 |
|
| 2016 |
Lomberk GA, Mathison A, Missfeldt M, Salmonson A, Kossak S, Buttar N, Urrutia R. Inhibition of pancreatic cancer by targeting the epigenetic EZH2 complex. Journal of Clinical Oncology. 34. DOI: 10.1200/Jco.2016.34.15_Suppl.E15736 |
0.383 |
|
| 2016 |
Yaqoob U, Drinane M, Yu H, Tang D, Kostallari E, Lomberk G, Mathison A, Urrutia R, Shah V. 505 Synectin Regulates Liver Fibrosis In Vivo and In Vitro Through Regulated Production of Insulin Like Growth Factor Binding Protein-3 in Hepatic Stellate Cells Gastroenterology. 150. DOI: 10.1016/S0016-5085(16)33506-5 |
0.318 |
|
| 2016 |
Syed SA, Lee JH, Hayashi Y, Gajdos GB, Asuzu DT, Nie JJ, Yan H, Rubin BP, Urrutia R, Klein S, Saur D, Zhang Z, Ordog T. Sa1677 The Polycomb Histone Lysine Methyltransferase EZH2 Controls Interstitial Cell of Cajal Populations by Regulating Stem Cell Differentiation and Self-Renewal Gastroenterology. 150: S343-S344. DOI: 10.1016/S0016-5085(16)31206-9 |
0.32 |
|
| 2016 |
Hessmann E, Chen N-, Zhang J-, Urrutia R, Koenig AO, Ellenrieder V. Nuclear transcription complexes mediate inflammation-associated pancreatic carcinogenesis Pancreatology. 16. DOI: 10.1016/J.Pan.2015.12.084 |
0.342 |
|
| 2015 |
Grasso D, Bintz J, Lomberk G, Molejon MI, Loncle C, Garcia MN, Lopez MB, Urrutia R, Iovanna JL. Pivotal Role of the Chromatin Protein Nupr1 in Kras-Induced Senescence and Transformation. Scientific Reports. 5: 17549. PMID 26617245 DOI: 10.1038/Srep17549 |
0.385 |
|
| 2015 |
Branham MT, Campoy E, Laurito S, Branham R, Urrutia G, Orozco J, Gago F, Urrutia R, Roqué M. Epigenetic regulation of ID4 in the determination of the BRCAness phenotype in breast cancer. Breast Cancer Research and Treatment. PMID 26610810 DOI: 10.1007/S10549-015-3648-0 |
0.325 |
|
| 2015 |
Loncle C, Bonjoch L, Folch-Puy E, Lopez-Millan MB, Lac S, Molejon MI, Chuluyan E, Cordelier P, Dubus P, Lomberk G, Urrutia R, Closa D, Iovanna JL. IL17 Functions through the Novel REG3β–JAK2–STAT3 Inflammatory Pathway to Promote the Transition from Chronic Pancreatitis to Pancreatic Cancer Cancer Research. 75: 4852-4862. PMID 26404002 DOI: 10.1158/0008-5472.Can-15-0896 |
0.376 |
|
| 2015 |
Guo Y, Fan Y, Zhang J, Lomberk GA, Zhou Z, Sun L, Mathison AJ, Garcia-Barrio MT, Zhang J, Zeng L, Li L, Pennathur S, Willer CJ, Rader DJ, Urrutia R, et al. Perhexiline activates KLF14 and reduces atherosclerosis by modulating ApoA-I production. The Journal of Clinical Investigation. PMID 26368306 DOI: 10.1172/Jci79048 |
0.305 |
|
| 2015 |
Lomberk GA, Urrutia R. The Triple-Code Model for Pancreatic Cancer: Cross Talk Among Genetics, Epigenetics, and Nuclear Structure. Surgical Clinics of North America. 95: 935-952. PMID 26315515 DOI: 10.1016/J.Suc.2015.05.011 |
0.348 |
|
| 2015 |
Mathison A, Escande C, Calvo E, Seo S, White T, Salmonson A, Faubion WA, Buttar N, Iovanna J, Lomberk G, Chini EN, Urrutia R. Phenotypic Characterization of Mice Carrying Homozygous Deletion of KLF11, a Gene in Which Mutations Cause Human Neonatal and MODY VII Diabetes. Endocrinology. 156: 3581-95. PMID 26248217 DOI: 10.1210/En.2015-1145 |
0.586 |
|
| 2015 |
Leonard PH, Grzenda A, Mathison A, Morbeck DE, Fredrickson JR, de Assuncao TM, Christensen T, Salisbury J, Calvo E, Iovanna J, Coddington CC, Urrutia R, Lomberk G. The Aurora A-HP1γ pathway regulates gene expression and mitosis in cells from the sperm lineage. Bmc Developmental Biology. 15: 23. PMID 26021315 DOI: 10.1186/S12861-015-0073-X |
0.708 |
|
| 2015 |
Lopez MB, Garcia MN, Grasso D, Bintz J, Molejon MI, Velez G, Lomberk G, Neira JL, Urrutia R, Iovanna J. Functional Characterization of Nupr1L, a novelp53-Regulated Isoform of the High Mobility Group (HMG)-Related Protumoral Protein Nupr1. Journal of Cellular Physiology. PMID 25899918 DOI: 10.1002/Jcp.25022 |
0.41 |
|
| 2015 |
De Assuncao TM, Sun Y, Jalan-Sakrikar N, Drinane MC, Huang BQ, Li Y, Davila JI, Wang R, O'Hara SP, Lomberk GA, Urrutia RA, Ikeda Y, Huebert RC. Development and characterization of human-induced pluripotent stem cell-derived cholangiocytes. Laboratory Investigation; a Journal of Technical Methods and Pathology. 95: 684-96. PMID 25867762 DOI: 10.1038/Labinvest.2015.51 |
0.343 |
|
| 2015 |
Sarmento OF, Svingen PA, Xiong Y, Xavier RJ, McGovern D, Smyrk TC, Papadakis KA, Urrutia RA, Faubion WA. A novel role for KLF14 in T regulatory cell differentiation. Cellular and Molecular Gastroenterology and Hepatology. 1: 188-202.e4. PMID 25750932 DOI: 10.1016/J.Jcmgh.2014.12.007 |
0.403 |
|
| 2015 |
Floris I, Descamps B, Vardeu A, Mitić T, Posadino AM, Shantikumar S, Sala-Newby G, Capobianco G, Mangialardi G, Howard L, Dessole S, Urrutia R, Pintus G, Emanueli C. Gestational diabetes mellitus impairs fetal endothelial cell functions through a mechanism involving microRNA-101 and histone methyltransferase enhancer of zester homolog-2. Arteriosclerosis, Thrombosis, and Vascular Biology. 35: 664-74. PMID 25614281 DOI: 10.1161/Atvbaha.114.304730 |
0.331 |
|
| 2015 |
Kang N, Shah VH, Urrutia R. Membrane-to-Nucleus Signals and Epigenetic Mechanisms for Myofibroblastic Activation and Desmoplastic Stroma: Potential Therapeutic Targets for Liver Metastasis? Molecular Cancer Research : McR. 13: 604-12. PMID 25548101 DOI: 10.1158/1541-7786.Mcr-14-0542 |
0.362 |
|
| 2015 |
Loft A, Forss I, Siersbæk MS, Schmidt SF, Larsen AS, Madsen JG, Pisani DF, Nielsen R, Aagaard MM, Mathison A, Neville MJ, Urrutia R, Karpe F, Amri EZ, Mandrup S. Browning of human adipocytes requires KLF11 and reprogramming of PPARγ superenhancers. Genes & Development. 29: 7-22. PMID 25504365 DOI: 10.1101/Gad.250829.114 |
0.33 |
|
| 2015 |
Harris S, Johnson S, Duncan JW, Udemgba C, Meyer JH, Albert PR, Lomberk G, Urrutia R, Ou XM, Stockmeier CA, Wang JM. Evidence revealing deregulation of the KLF11-MAO A pathway in association with chronic stress and depressive disorders. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 1373-82. PMID 25502632 DOI: 10.1038/Npp.2014.321 |
0.315 |
|
| 2015 |
Papadakis KA, Krempski J, Reiter J, Svingen P, Xiong Y, Sarmento OF, Huseby A, Johnson AJ, Lomberk GA, Urrutia RA, Faubion WA. Krüppel-like factor KLF10 regulates transforming growth factor receptor II expression and TGF-β signaling in CD8+ T lymphocytes. American Journal of Physiology. Cell Physiology. 308: C362-71. PMID 25472963 DOI: 10.1152/Ajpcell.00262.2014 |
0.303 |
|
| 2015 |
Mitić T, Caporali A, Floris I, Meloni M, Marchetti M, Urrutia R, Angelini GD, Emanueli C. EZH2 modulates angiogenesis in vitro and in a mouse model of limb ischemia. Molecular Therapy : the Journal of the American Society of Gene Therapy. 23: 32-42. PMID 25189741 DOI: 10.1038/Mt.2014.163 |
0.357 |
|
| 2014 |
Grasso D, Garcia MN, Hamidi T, Cano C, Calvo E, Lomberk G, Urrutia R, Iovanna JL. Pancreatitis promotes oncogenic Kras(G12D)-induced pancreatic transformation through activation of Nupr1. Molecular & Cellular Oncology. 1: e29913. PMID 27308320 DOI: 10.4161/Mco.29913 |
0.351 |
|
| 2014 |
Garcia MN, Grasso D, Lopez-Millan MB, Hamidi T, Loncle C, Tomasini R, Lomberk G, Porteu F, Urrutia R, Iovanna JL. IER3 supports KRASG12D-dependent pancreatic cancer development by sustaining ERK1/2 phosphorylation. The Journal of Clinical Investigation. 124: 4709-22. PMID 25250570 DOI: 10.1172/Jci76037 |
0.393 |
|
| 2014 |
Koh KH, Pan X, Zhang W, McLachlan A, Urrutia R, Jeong H. Krüppel-like factor 9 promotes hepatic cytochrome P450 2D6 expression during pregnancy in CYP2D6-humanized mice. Molecular Pharmacology. 86: 727-35. PMID 25217496 DOI: 10.1124/Mol.114.093666 |
0.35 |
|
| 2014 |
Urrutia R, Velez G, Lin M, Lomberk G, Neira JL, Iovanna J. Evidence supporting the existence of a NUPR1-like family of helix-loop-helix chromatin proteins related to, yet distinct from, AT hook-containing HMG proteins Journal of Molecular Modeling. 20: 2357-2357. PMID 25056123 DOI: 10.1007/S00894-014-2357-7 |
0.34 |
|
| 2014 |
Xiong Y, Svingen PA, Sarmento OO, Smyrk TC, Dave M, Khanna S, Lomberk GA, Urrutia RA, Faubion WA. Differential coupling of KLF10 to Sin3-HDAC and PCAF regulates the inducibility of the FOXP3 gene. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 307: R608-20. PMID 24944246 DOI: 10.1152/Ajpregu.00085.2014 |
0.381 |
|
| 2014 |
Grasso D, Garcia MN, Hamidi T, Cano C, Calvo E, Lomberk G, Urrutia R, Iovanna JL. Genetic inactivation of the pancreatitis-inducible gene Nupr1 impairs PanIN formation by modulating Kras(G12D)-induced senescence. Cell Death and Differentiation. 21: 1633-41. PMID 24902898 DOI: 10.1038/Cdd.2014.74 |
0.432 |
|
| 2014 |
Calvo E, Grzenda A, Lomberk G, Mathison A, Iovanna J, Urrutia R. Single and combinatorial chromatin coupling events underlies the function of transcript factor Krüppel-like factor 11 in the regulation of gene networks. Bmc Molecular Biology. 15: 10. PMID 24885560 DOI: 10.1186/1471-2199-15-10 |
0.712 |
|
| 2014 |
de Assuncao TM, Lomberk G, Cao S, Yaqoob U, Mathison A, Simonetto DA, Huebert RC, Urrutia RA, Shah VH. New role for Kruppel-like factor 14 as a transcriptional activator involved in the generation of signaling lipids. The Journal of Biological Chemistry. 289: 15798-809. PMID 24759103 DOI: 10.1074/Jbc.M113.544346 |
0.405 |
|
| 2014 |
Baumgart S, Chen NM, Siveke JT, König A, Zhang JS, Singh SK, Wolf E, Bartkuhn M, Esposito I, Heßmann E, Reinecke J, Nikorowitsch J, Brunner M, Singh G, Fernandez-Zapico ME, ... ... Urrutia R, et al. Inflammation-induced NFATc1-STAT3 transcription complex promotes pancreatic cancer initiation by KrasG12D. Cancer Discovery. 4: 688-701. PMID 24694735 DOI: 10.1158/2159-8290.Cd-13-0593 |
0.42 |
|
| 2014 |
Ou XM, Udemgba C, Wang N, Dai X, Lomberk G, Seo S, Urrutia R, Wang J, Duncan J, Harris S, Fairbanks CA, Zhang X. Diabetes-causing gene, kruppel-like factor 11, modulates the antinociceptive response of chronic ethanol intake. Alcoholism, Clinical and Experimental Research. 38: 401-8. PMID 24428663 DOI: 10.1111/Acer.12258 |
0.584 |
|
| 2014 |
Cano CE, Hamidi T, Garcia MN, Grasso D, Loncle C, Garcia S, Calvo E, Lomberk G, Dusetti N, Bartholin L, Urrutia R, Iovanna JL. Genetic inactivation of Nupr1 acts as a dominant suppressor event in a two-hit model of pancreatic carcinogenesis. Gut. 63: 984-95. PMID 24026351 DOI: 10.1136/Gutjnl-2013-305221 |
0.381 |
|
| 2014 |
Goicoechea SM, García-Mata R, Staub J, Valdivia A, Sharek L, McCulloch CG, Hwang RF, Urrutia R, Yeh JJ, Kim HJ, Otey CA. Palladin promotes invasion of pancreatic cancer cells by enhancing invadopodia formation in cancer-associated fibroblasts. Oncogene. 33: 1265-73. PMID 23524582 DOI: 10.1038/Onc.2013.68 |
0.403 |
|
| 2014 |
Bi Y, Li J, Ji B, Kang N, Urrutia RA, Shah V. Tu1910 Pancreatic Stellate Cell Sphingosine 1 Phosphate Receptor-2 Regulates Cancer Growth In Vivo Through Effects on Tumor Microenvironment Gastroenterology. 146. DOI: 10.1016/S0016-5085(14)63165-6 |
0.357 |
|
| 2014 |
Sharma AN, Kossak S, Chowdhury S, Chandra R, Singh I, Baruah A, DeMars CJ, Iyer PG, Urrutia RA, Wang KK, Krishnadath KK, Buttar N. Sa1965 Garcinol Interferes With Oncogenic IL1b-STAT3 and Facilitates Tumor Suppressive KLF11-Sin3A to Down-Regulate AKT1 Expression and Cell Growth in Barrett's Epithelium Gastroenterology. 146. DOI: 10.1016/S0016-5085(14)61234-8 |
0.377 |
|
| 2013 |
Hayashi Y, Asuzu DT, Gibbons SJ, Aarsvold KH, Bardsley MR, Lomberk GA, Mathison AJ, Kendrick ML, Shen KR, Taguchi T, Gupta A, Rubin BP, Fletcher JA, Farrugia G, Urrutia RA, et al. Membrane-to-nucleus signaling links insulin-like growth factor-1- and stem cell factor-activated pathways. Plos One. 8: e76822. PMID 24116170 DOI: 10.1371/Journal.Pone.0076822 |
0.388 |
|
| 2013 |
Mathison A, Grzenda A, Lomberk G, Velez G, Buttar N, Tietz P, Hendrickson H, Liebl A, Xiong YY, Gores G, Fernandez-Zapico M, Larusso NF, Faubion W, Shah VH, Urrutia R. Role for Krüppel-like transcription factor 11 in mesenchymal cell function and fibrosis. Plos One. 8: e75311. PMID 24069400 DOI: 10.1371/Journal.Pone.0075311 |
0.729 |
|
| 2013 |
Grzenda A, Leonard P, Seo S, Mathison AJ, Urrutia G, Calvo E, Iovanna J, Urrutia R, Lomberk G. Functional impact of Aurora A-mediated phosphorylation of HP1γ at serine 83 during cell cycle progression. Epigenetics & Chromatin. 6: 21. PMID 23829974 DOI: 10.1186/1756-8935-6-21 |
0.762 |
|
| 2013 |
Seo S, Grzenda A, Lomberk G, Ou XM, Cruciani RA, Urrutia R. Epigenetics: a promising paradigm for better understanding and managing pain. The Journal of Pain : Official Journal of the American Pain Society. 14: 549-57. PMID 23602266 DOI: 10.1016/J.Jpain.2013.01.772 |
0.742 |
|
| 2013 |
Lomberk G, Grzenda A, Mathison A, Escande C, Zhang JS, Calvo E, Miller LJ, Iovanna J, Chini EN, Fernandez-Zapico ME, Urrutia R. Krüppel-like factor 11 regulates the expression of metabolic genes via an evolutionarily conserved protein interaction domain functionally disrupted in maturity onset diabetes of the young. The Journal of Biological Chemistry. 288: 17745-58. PMID 23589285 DOI: 10.1074/Jbc.M112.434670 |
0.709 |
|
| 2013 |
Daftary GS, Zheng Y, Tabbaa ZM, Schoolmeester JK, Gada RP, Grzenda AL, Mathison AJ, Keeney GL, Lomberk GA, Urrutia R. A novel role of the Sp/KLF transcription factor KLF11 in arresting progression of endometriosis. Plos One. 8: e60165. PMID 23555910 DOI: 10.1371/Journal.Pone.0060165 |
0.708 |
|
| 2013 |
Gilabert M, Vaccaro MI, Fernandez-Zapico ME, Calvo EL, Turrini O, Secq V, Garcia S, Moutardier V, Lomberk G, Dusetti N, Urrutia R, Iovanna JL. Novel role of VMP1 as modifier of the pancreatic tumor cell response to chemotherapeutic drugs. Journal of Cellular Physiology. 228: 1834-43. PMID 23460482 DOI: 10.1002/Jcp.24343 |
0.318 |
|
| 2013 |
Paulo JA, Urrutia R, Kadiyala V, Banks P, Conwell DL, Steen H. Cross-species analysis of nicotine-induced proteomic alterations in pancreatic cells Proteomics. 13: 1499-1512. PMID 23456891 DOI: 10.1002/Pmic.201200492 |
0.309 |
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| 2013 |
Grzenda A, Lomberk G, Svingen P, Mathison A, Calvo E, Iovanna J, Xiong Y, Faubion W, Urrutia R. Functional characterization of EZH2β reveals the increased complexity of EZH2 isoforms involved in the regulation of mammalian gene expression. Epigenetics & Chromatin. 6: 3. PMID 23448518 DOI: 10.1186/1756-8935-6-3 |
0.718 |
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| 2013 |
Yin KJ, Fan Y, Hamblin M, Zhang J, Zhu T, Li S, Hawse JR, Subramaniam M, Song CZ, Urrutia R, Lin JD, Chen YE. KLF11 mediates PPARγ cerebrovascular protection in ischaemic stroke. Brain : a Journal of Neurology. 136: 1274-87. PMID 23408111 DOI: 10.1093/Brain/Awt002 |
0.302 |
|
| 2013 |
Iovanna JL, Marks DL, Fernandez-Zapico ME, Urrutia R. Mechanistic insights into self-reinforcing processes driving abnormal histogenesis during the development of pancreatic cancer. The American Journal of Pathology. 182: 1078-86. PMID 23375449 DOI: 10.1016/J.Ajpath.2012.12.004 |
0.375 |
|
| 2013 |
McCleary-Wheeler AL, Lomberk GA, Weiss FU, Schneider G, Fabbri M, Poshusta TL, Dusetti NJ, Baumgart S, Iovanna JL, Ellenrieder V, Urrutia R, Fernandez-Zapico ME. Insights into the epigenetic mechanisms controlling pancreatic carcinogenesis. Cancer Letters. 328: 212-21. PMID 23073473 DOI: 10.1016/J.Canlet.2012.10.005 |
0.366 |
|
| 2013 |
Hamidi T, Cano CE, Grasso D, Garcia MN, Sandi MJ, Calvo EL, Dagorn JC, Lomberk G, Goruppi S, Urrutia R, Carracedo A, Velasco G, Iovanna JL. NUPR1 works against the metabolic stress-induced autophagy-associated cell death in pancreatic cancer cells. Autophagy. 9: 95-7. PMID 23047430 DOI: 10.4161/Auto.22258 |
0.342 |
|
| 2013 |
Sharma AN, Chowdhury S, Lomberk GA, DeMars CJ, Iyer PG, Limburg PJ, Krishnadath KK, Wang KK, Urrutia RA, Buttar N. Sa1685 Chromatin Remodeling via Sin3-HDAC and Hp1-Hmt Pathways in the Regulation of Oncogenic AKT1 Gastroenterology. 144. DOI: 10.1016/S0016-5085(13)60998-1 |
0.35 |
|
| 2013 |
Sharma AN, Chowdhury S, DeMars CJ, Lomberk GA, Lutzke LS, Iyer PG, Wang KK, Krishnadath KK, Urrutia RA, Buttar N. 388 IL-1β-STAT3 Mediated Up-Regulation of AKT1 Expression in Barrett's Esophagus: A Potential Link Between Inflammation and Carcinogenesis Gastroenterology. 144. DOI: 10.1016/S0016-5085(13)60273-5 |
0.306 |
|
| 2013 |
Lomberk G, Urrutia R. Studies on polycomb identify new EZH2-type epigenetic oncogene for pancreatic cancer Pancreatology. 13. DOI: 10.1016/J.Pan.2013.07.069 |
0.342 |
|
| 2013 |
Lomberk G, Grzenda A, Mathison A, Calvo E, Zapico MF, Iovanna J, Urrutia R. Modeling of metabolic gene networks regulated by KLF-mediated epigenetic pathways working at the intersection of pancreatic cancer and diabetes Pancreatology. 13. DOI: 10.1016/J.Pan.2012.12.227 |
0.7 |
|
| 2013 |
Grzenda A, Leonard P, Urrutia G, Mathison A, Fernandez-Zapico M, Urrutia R, Lomberk G. Aurora A phosphorylation of the epigenetic regulator HP1γ mediates cell division in pancreatic cancer cells Pancreatology. 13. DOI: 10.1016/J.Pan.2012.12.152 |
0.722 |
|
| 2013 |
Grzenda A, Lomberk G, Svingen P, Mathison A, Calvo E, Iovanna J, Xiong Y, Faubion W, Urrutia R. Functional characterization of EZH2β, a newly identified epigenetic oncogene for pancreatic cancer Pancreatology. 13. DOI: 10.1016/J.Pan.2012.12.151 |
0.703 |
|
| 2013 |
McCleary-Wheeler AL, Lomberk GA, Weiss FU, Schneider G, Fabbri M, Poshusta TL, Dusetti NJ, Baumgart S, Iovanna JL, Ellenrieder V, Urrutia R, Fernandez-Zapico ME. Corrigendum to "Insights into the epigenetic mechanisms controlling pancreatic carcinogenesis" [Cancer Lett. 328 (2) (2012) 212-221] Cancer Letters. 337: 143-144. DOI: 10.1016/J.Canlet.2013.05.024 |
0.339 |
|
| 2012 |
Fan Y, Guo Y, Zhang J, Subramaniam M, Song CZ, Urrutia R, Chen YE. Krüppel-like factor-11, a transcription factor involved in diabetes mellitus, suppresses endothelial cell activation via the nuclear factor-κB signaling pathway. Arteriosclerosis, Thrombosis, and Vascular Biology. 32: 2981-8. PMID 23042817 DOI: 10.1161/Atvbaha.112.300349 |
0.337 |
|
| 2012 |
Hamidi T, Cano CE, Grasso D, Garcia MN, Sandi MJ, Calvo EL, Dagorn JC, Lomberk G, Urrutia R, Goruppi S, Carracedo A, Velasco G, Iovanna JL. Nupr1-aurora kinase A pathway provides protection against metabolic stress-mediated autophagic-associated cell death. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 5234-46. PMID 22899799 DOI: 10.1158/1078-0432.Ccr-12-0026 |
0.371 |
|
| 2012 |
Xiong Y, Khanna S, Grzenda AL, Sarmento OF, Svingen PA, Lomberk GA, Urrutia RA, Faubion WA. Polycomb antagonizes p300/CREB-binding protein-associated factor to silence FOXP3 in a Kruppel-like factor-dependent manner. The Journal of Biological Chemistry. 287: 34372-85. PMID 22896699 DOI: 10.1074/Jbc.M111.325332 |
0.721 |
|
| 2012 |
Cano CE, Sandí MJ, Hamidi T, Calvo EL, Turrini O, Bartholin L, Loncle C, Secq V, Garcia S, Lomberk G, Kroemer G, Urrutia R, Iovanna JL. Homotypic cell cannibalism, a cell-death process regulated by the nuclear protein 1, opposes to metastasis in pancreatic cancer. Embo Molecular Medicine. 4: 964-79. PMID 22821859 DOI: 10.1002/Emmm.201201255 |
0.396 |
|
| 2012 |
Grunewald M, Johnson S, Lu D, Wang Z, Lomberk G, Albert PR, Stockmeier CA, Meyer JH, Urrutia R, Miczek KA, Austin MC, Wang J, Paul IA, Woolverton WL, Seo S, et al. Mechanistic role for a novel glucocorticoid-KLF11 (TIEG2) protein pathway in stress-induced monoamine oxidase A expression. The Journal of Biological Chemistry. 287: 24195-206. PMID 22628545 DOI: 10.1074/Jbc.M112.373936 |
0.585 |
|
| 2012 |
Hamidi T, Algül H, Cano CE, Sandi MJ, Molejon MI, Riemann M, Calvo EL, Lomberk G, Dagorn JC, Weih F, Urrutia R, Schmid RM, Iovanna JL. Nuclear protein 1 promotes pancreatic cancer development and protects cells from stress by inhibiting apoptosis. The Journal of Clinical Investigation. 122: 2092-103. PMID 22565310 DOI: 10.1172/Jci60144 |
0.406 |
|
| 2012 |
Seo S, Lomberk G, Mathison A, Buttar N, Podratz J, Calvo E, Iovanna J, Brimijoin S, Windebank A, Urrutia R. Krüppel-like factor 11 differentially couples to histone acetyltransferase and histone methyltransferase chromatin remodeling pathways to transcriptionally regulate dopamine D2 receptor in neuronal cells. The Journal of Biological Chemistry. 287: 12723-35. PMID 22375010 DOI: 10.1074/Jbc.M112.351395 |
0.646 |
|
| 2012 |
Lomberk G, Mathison AJ, Grzenda A, Seo S, DeMars CJ, Rizvi S, Bonilla-Velez J, Calvo E, Fernandez-Zapico ME, Iovanna J, Buttar NS, Urrutia R. Sequence-specific recruitment of heterochromatin protein 1 via interaction with Krüppel-like factor 11, a human transcription factor involved in tumor suppression and metabolic diseases. The Journal of Biological Chemistry. 287: 13026-39. PMID 22318730 DOI: 10.1074/Jbc.M112.342634 |
0.786 |
|
| 2012 |
Daftary GS, Lomberk GA, Buttar NS, Allen TW, Grzenda A, Zhang J, Zheng Y, Mathison AJ, Gada RP, Calvo E, Iovanna JL, Billadeau DD, Prendergast FG, Urrutia R. Detailed structural-functional analysis of the Krüppel-like factor 16 (KLF16) transcription factor reveals novel mechanisms for silencing Sp/KLF sites involved in metabolism and endocrinology. The Journal of Biological Chemistry. 287: 7010-25. PMID 22203677 DOI: 10.1074/Jbc.M111.266007 |
0.731 |
|
| 2012 |
Chowdhury S, DeMars CJ, Elebiary A, Singh A, Lutzke LS, Wang KK, Lomberk GA, Faubion WA, Daftary G, Urrutia RA, Buttar N. 407a Oncogenic AKT1 Regulation by Tumor Suppressor KLF11: Implications in Growth Regulation During Neoplastic Transformation in Barrett's Esophagus and Interference by Carcinogenic Bile Acid Dependent Erk2 and PKCa Activation Gastroenterology. 142. DOI: 10.1016/S0016-5085(12)60344-8 |
0.394 |
|
| 2011 |
Paulo JA, Urrutia R, Banks PA, Conwell DL, Steen H. Proteomic analysis of a rat pancreatic stellate cell line using liquid chromatography tandem mass spectrometry (LC-MS/MS). Journal of Proteomics. 75: 708-17. PMID 21968429 DOI: 10.1016/J.Jprot.2011.09.009 |
0.345 |
|
| 2011 |
Xiao TZ, Bhatia N, Urrutia R, Lomberk GA, Simpson A, Longley BJ. MAGE I transcription factors regulate KAP1 and KRAB domain zinc finger transcription factor mediated gene repression. Plos One. 6: e23747. PMID 21876767 DOI: 10.1371/Journal.Pone.0023747 |
0.428 |
|
| 2011 |
Paulo JA, Urrutia R, Banks PA, Conwell DL, Steen H. Proteomic analysis of an immortalized mouse pancreatic stellate cell line identifies differentially-expressed proteins in activated vs nonproliferating cell states. Journal of Proteome Research. 10: 4835-44. PMID 21838295 DOI: 10.1021/Pr2006318 |
0.368 |
|
| 2011 |
Singh SK, Baumgart S, Singh G, König AO, Reutlinger K, Hofbauer LC, Barth P, Gress TM, Lomberk G, Urrutia R, Fernandez-Zapico ME, Ellenrieder V. Disruption of a nuclear NFATc2 protein stabilization loop confers breast and pancreatic cancer growth suppression by zoledronic acid. The Journal of Biological Chemistry. 286: 28761-71. PMID 21628454 DOI: 10.1074/Jbc.M110.197533 |
0.357 |
|
| 2011 |
Bonnefond A, Lomberk G, Buttar N, Busiah K, Vaillant E, Lobbens S, Yengo L, Dechaume A, Mignot B, Simon A, Scharfmann R, Neve B, Tanyolaç S, Hodoglugil U, Pattou F, ... ... Urrutia R, et al. Disruption of a novel Kruppel-like transcription factor p300-regulated pathway for insulin biosynthesis revealed by studies of the c.-331 INS mutation found in neonatal diabetes mellitus. The Journal of Biological Chemistry. 286: 28414-24. PMID 21592955 DOI: 10.1074/Jbc.M110.215822 |
0.354 |
|
| 2011 |
Thabut D, Routray C, Lomberk G, Shergill U, Glaser K, Huebert R, Patel L, Masyuk T, Blechacz B, Vercnocke A, Ritman E, Ehman R, Urrutia R, Shah V. Complementary vascular and matrix regulatory pathways underlie the beneficial mechanism of action of sorafenib in liver fibrosis. Hepatology (Baltimore, Md.). 54: 573-85. PMID 21567441 DOI: 10.1002/Hep.24427 |
0.324 |
|
| 2011 |
Grzenda A, Ordog T, Urrutia R. Polycomb and the emerging epigenetics of pancreatic cancer. Journal of Gastrointestinal Cancer. 42: 100-11. PMID 21336826 DOI: 10.1007/S12029-011-9262-4 |
0.726 |
|
| 2011 |
Grasso D, Ropolo A, Lo Ré A, Boggio V, Molejón MI, Iovanna JL, Gonzalez CD, Urrutia R, Vaccaro MI. Zymophagy, a novel selective autophagy pathway mediated by VMP1-USP9x-p62, prevents pancreatic cell death. The Journal of Biological Chemistry. 286: 8308-24. PMID 21173155 DOI: 10.1074/Jbc.M110.197301 |
0.373 |
|
| 2011 |
Fernandez-Zapico ME, Lomberk GA, Tsuji S, DeMars CJ, Bardsley MR, Lin YH, Almada LL, Han JJ, Mukhopadhyay D, Ordog T, Buttar NS, Urrutia R. A functional family-wide screening of SP/KLF proteins identifies a subset of suppressors of KRAS-mediated cell growth. The Biochemical Journal. 435: 529-37. PMID 21171965 DOI: 10.1042/Bj20100773 |
0.395 |
|
| 2011 |
Singh A, DeMars CJ, Virk CS, Lomberk GA, Chowdhury S, Faridar A, Seo S, Lutzke LS, Wang KK, Urrutia RA, Buttar N. The Tumor Suppressor KLF11 and Bile Acid Modulate Notch Signaling in Barrett's Epithelium Gastroenterology. 140. DOI: 10.1016/S0016-5085(11)63379-9 |
0.542 |
|
| 2011 |
Chowdhury S, Faridar A, DeMars CJ, Singh A, Lomberk GA, Prasad GA, Urrutia RA, Buttar N. HDAC-Mediated Gene Silencing of AKT1 by the Tumor Suppressor KLF11: Implications in Growth Regulation and Bile Salt Mediated Neoplastic Transformation in Barrett's Esophagus Gastroenterology. 140. DOI: 10.1016/S0016-5085(11)60666-5 |
0.341 |
|
| 2011 |
Hayashi Y, Asuzu DT, Bardsley MR, Lomberk GA, Farrugia G, Urrutia RA, Ordog T. Chromatin-Remodeling Events Reveal a Novel Paradigm for the Epigenetic Control of Stem Cell Factor ( Kitl ) Expression in Gastrointestinal Smooth Muscles, Mesenchymal Cells and Stromal Tumors Gastroenterology. 140: S-120. DOI: 10.1016/S0016-5085(11)60488-5 |
0.342 |
|
| 2011 |
Asuzu DT, McGehee CD, Hayashi Y, Bardsley MR, Grzenda AL, Lomberk GA, Farrugia G, Urrutia RA, Ordog T. Epigenetic Control of Kit Expression in Murine Kit Low Interstitial Cell of Cajal (ICC) Stem Cells and Gastrointestinal Stromal Tumors (GIST) Gastroenterology. 140: S-119-S-120. DOI: 10.1016/S0016-5085(11)60485-X |
0.687 |
|
| 2010 |
Cao Y, Szabolcs A, Dutta SK, Yaqoob U, Jagavelu K, Wang L, Leof EB, Urrutia RA, Shah VH, Mukhopadhyay D. Neuropilin-1 mediates divergent R-Smad signaling and the myofibroblast phenotype. The Journal of Biological Chemistry. 285: 31840-8. PMID 20675371 DOI: 10.1074/Jbc.M110.151696 |
0.315 |
|
| 2010 |
Lomberk GA, Imoto I, Gebelein B, Urrutia R, Cook TA. Conservation of the TGFbeta/Labial homeobox signaling loop in endoderm-derived cells between Drosophila and mammals. Pancreatology : Official Journal of the International Association of Pancreatology (Iap) ... [Et Al.]. 10: 74-84. PMID 20339309 DOI: 10.1159/000276895 |
0.413 |
|
| 2010 |
Das A, Shergill U, Thakur L, Sinha S, Urrutia R, Mukhopadhyay D, Shah VH. Ephrin B2/EphB4 pathway in hepatic stellate cells stimulates Erk-dependent VEGF production and sinusoidal endothelial cell recruitment. American Journal of Physiology. Gastrointestinal and Liver Physiology. 298: G908-15. PMID 20338920 DOI: 10.1152/Ajpgi.00510.2009 |
0.318 |
|
| 2010 |
Buttar NS, DeMars CJ, Lomberk G, Rizvi S, Bonilla-Velez J, Achra S, Rashtak S, Wang KK, Fernandez-Zapico ME, Urrutia R. Distinct role of Kruppel-like factor 11 in the regulation of prostaglandin E2 biosynthesis. The Journal of Biological Chemistry. 285: 11433-44. PMID 20154088 DOI: 10.1074/Jbc.M109.077065 |
0.403 |
|
| 2010 |
Mathison A, Liebl A, Bharucha J, Mukhopadhyay D, Lomberk G, Shah V, Urrutia R. Pancreatic Stellate Cell Models for Transcriptional Studies of Desmoplasia-Associated Genes Pancreatology. 10: 505-516. DOI: 10.1159/000320540 |
0.449 |
|
| 2009 |
Fernandez-Zapico ME, van Velkinburgh JC, Gutiérrez-Aguilar R, Neve B, Froguel P, Urrutia R, Stein R. MODY7 gene, KLF11, is a novel p300-dependent regulator of Pdx-1 (MODY4) transcription in pancreatic islet beta cells. The Journal of Biological Chemistry. 284: 36482-90. PMID 19843526 DOI: 10.1074/Jbc.M109.028852 |
0.397 |
|
| 2009 |
Guturu P, Shah V, Urrutia R. Interplay of tumor microenvironment cell types with parenchymal cells in pancreatic cancer development and therapeutic implications. Journal of Gastrointestinal Cancer. 40: 1-9. PMID 19513861 DOI: 10.1007/S12029-009-9071-1 |
0.341 |
|
| 2009 |
Grzenda A, Lomberk G, Zhang JS, Urrutia R. Sin3: master scaffold and transcriptional corepressor. Biochimica Et Biophysica Acta. 1789: 443-450. PMID 19505602 DOI: 10.1016/J.Bbagrm.2009.05.007 |
0.715 |
|
| 2009 |
Truty MJ, Lomberk G, Fernandez-Zapico ME, Urrutia R. Silencing of the transforming growth factor-beta (TGFbeta) receptor II by Kruppel-like factor 14 underscores the importance of a negative feedback mechanism in TGFbeta signaling. The Journal of Biological Chemistry. 284: 6291-300. PMID 19088080 DOI: 10.1074/Jbc.M807791200 |
0.416 |
|
| 2009 |
Lomberk G, Urrutia R. Primers on Molecular Pathways — Caspase Pathway Pancreatology. 9: 6-8. PMID 19077449 DOI: 10.1159/000178860 |
0.352 |
|
| 2009 |
Bhardwaj Y, DeMars CJ, Achra S, Anderson M, Prasad GA, Wang KK, Urrutia RA, Buttar N. T1898 SOX2 and CDx2, Transcriptional Regulators of Early Differentation, Play a Key Role in the Development of Acid and Bile-Associated Columnar Metaplasia Gastroenterology. 136. DOI: 10.1016/S0016-5085(09)62746-3 |
0.314 |
|
| 2009 |
Rashtak S, DeMars CJ, Lomberk GA, Stein R, Urrutia RA, Buttar N. M1747 Knockout of KLF11, a Tumor Suppressor for Pancreatic Cancer, Displays An Abnormal Glucose Metabolism Gastroenterology. 136: A-423. DOI: 10.1016/S0016-5085(09)61947-8 |
0.357 |
|
| 2008 |
Lomberk G, Mathison AJ, Grzenda A, Urrutia R. The sunset of somatic genetics and the dawn of epigenetics: a new frontier in pancreatic cancer research. Current Opinion in Gastroenterology. 24: 597-602. PMID 19122501 DOI: 10.1097/Mog.0B013E32830B111D |
0.694 |
|
| 2008 |
Decker NK, Abdelmoneim SS, Yaqoob U, Hendrickson H, Hormes J, Bentley M, Pitot H, Urrutia R, Gores GJ, Shah VH. Nitric oxide regulates tumor cell cross-talk with stromal cells in the tumor microenvironment of the liver. The American Journal of Pathology. 173: 1002-12. PMID 18755846 DOI: 10.2353/Ajpath.2008.080158 |
0.307 |
|
| 2008 |
Lomberk G, Urrutia R. Primers on Molecular Pathways – Notch Pancreatology. 8: 103-104. PMID 18382095 DOI: 10.1159/000123603 |
0.401 |
|
| 2008 |
Aerssens J, Camilleri M, Talloen W, Thielemans L, Göhlmann HW, Van Den Wyngaert I, Thielemans T, De Hoogt R, Andrews CN, Bharucha AE, Carlson PJ, Busciglio I, Burton DD, Smyrk T, Urrutia R, et al. Alterations in mucosal immunity identified in the colon of patients with irritable bowel syndrome. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. 6: 194-205. PMID 18237869 DOI: 10.1016/J.Cgh.2007.11.012 |
0.318 |
|
| 2008 |
Ilyas S, Rizvi Z, DeMars C, Bhardwaj Y, Achra S, Lomberk G, Buttar N, Urrutia R. Urso And Aspirin In Combination Downregulate Pancreatic Cancer Cell Survival Pancreas. 37: 475-476. DOI: 10.1097/01.Mpa.0000335479.69474.3E |
0.331 |
|
| 2008 |
Bhardwaj Y, Achra S, DeMars C, Ilyas S, Rizvi Z, Lomberk G, Urrutia R, Buttar N. Distinct Inflammatory Mediators Regulate Survival Of Pancreatic Cancer Cells Pancreas. 37: 463. DOI: 10.1097/01.Mpa.0000335396.83508.D1 |
0.364 |
|
| 2008 |
Randriamahefa A, Rolle I, Grzenda A, Paul A, Lomberk G, Fernandez-Zapico M, Urrutia R. CHARACTERIZATION OF THE TGFβ MINUS MOUSE REVEALS A ROLE FOR FOXM1 AS A NOVEL PANCREATIC ONCOGENE Pancreas. 37: 491-492. DOI: 10.1097/01.Mpa.0000335369.62631.6F |
0.698 |
|
| 2008 |
Lomberk G, Zhang J, Truty MJ, Urrutia R. A NEW MOLECULAR MODEL FOR REGULATING THE TGFβ RECEPTOR II PROMOTER IN PANCREATIC CELLS Pancreas. 36: 223. DOI: 10.1097/01.Mpa.0000311855.41914.C8 |
0.342 |
|
| 2008 |
Evans W, Lokko C, Fernandez-Zapico ME, Randriamahefa A, Lomberk G, Urrutia R. A COOPERATIVE MODEL FOR PANCREATIC CANCER: ABNORMALITIES IN ONE TUMOR SUPPRESSOR PATHWAY (TGFβ) IN THE PANCREAS OF TRANSGENIC MICE INDUCES ALTERATION OF A SECOND TUMOR SUPPRESSOR PATHWAY (p53) Pancreas. 36: 223. DOI: 10.1097/01.Mpa.0000311854.03796.E5 |
0.317 |
|
| 2008 |
Lomberk G, Ilyas S, Mathison A, Conde-Perez A, Bonilla J, Demars C, Buttar N, Urrutia R. Klf11 Complexes With The Epigenetic Gene Silencer Protein, Hp1 To Mediate Tumor Suppressor Activities Pancreas. 37: 481. DOI: 10.1097/00006676-200811000-00112 |
0.347 |
|
| 2007 |
Lomberk G, Bensi D, Christensen T, Salisbury J, Urrutia R. HP1 γ HAS A SIGNIFICANT IMPACT ON CELL CYCLE PROGRESSION THROUGH THE REGULATION OF G2/M, CENTROSOME BIOLOGY AND, CHROMOSOMAL STABILITY IN PANCREATIC CANCER CELLS Pancreas. 35: 412. DOI: 10.1097/01.Mpa.0000297734.76617.E9 |
0.331 |
|
| 2007 |
Lomberk G, Zhang JS, Truty MJ, Urrutia R. A NEW MOLECULAR MODEL FOR REGULATION OF THE TGFβ RECEPTOR II PROMOTER VIA INTERACTION WITH THE LONG-TERM CHROMATIN REPRESSOR PROTEIN, HP1 WITH THE TUMOR SUPPRESSOR KLF11 Pancreas. 35: 412. DOI: 10.1097/01.Mpa.0000297733.68994.37 |
0.323 |
|
| 2007 |
Grzenda AL, Lomberk G, Urrutia R. DIFFERENT EZH2 ISOFORMS ARE EXPRESSED IN PANCREATIC CELLS Pancreas. 35: 404. DOI: 10.1097/01.Mpa.0000297707.83348.3D |
0.693 |
|
| 2007 |
Buttar N, DeMars C, Madhavan M, Mokkala V, Fernandez-Zapico ME, Wang K, Lutzke L, Urrutia R. Tumor Suppressor Protein, Kl11, Modulates Pge2 Synthesis Via The Regulation Of The Cplaá Pancreas. 35: 395. DOI: 10.1097/01.Mpa.0000297673.06288.Cc |
0.304 |
|
| 2007 |
Truty MJ, Tsuji S, Lomberk GA, Fernandez-Zapico M, Urrutia R. 38: Gene silencing in pancreatic cancer: Identification of novel transcriptional repressors Journal of Surgical Research. 137. DOI: 10.1016/J.Jss.2006.12.047 |
0.395 |
|
| 2006 |
Billadeau DD, Chatterjee S, Bramati P, Sreekumar R, Shah V, Hedin K, Urrutia R. Characterization of the CXCR4 signaling in pancreatic cancer cells. International Journal of Gastrointestinal Cancer. 37: 110-9. PMID 18175225 DOI: 10.1007/S12029-007-0011-7 |
0.367 |
|
| 2006 |
Lomberk G, Wallrath L, Urrutia R. The Heterochromatin Protein 1 family. Genome Biology. 7: 228. PMID 17224041 DOI: 10.1186/Gb-2006-7-7-228 |
0.366 |
|
| 2006 |
Das A, Fernandez-Zapico ME, Cao S, Yao J, Fiorucci S, Hebbel RP, Urrutia R, Shah VH. Disruption of an SP2/KLF6 repression complex by SHP is required for farnesoid X receptor-induced endothelial cell migration. The Journal of Biological Chemistry. 281: 39105-13. PMID 17071613 DOI: 10.1074/Jbc.M607720200 |
0.381 |
|
| 2006 |
Buttar NS, Fernandez-Zapico ME, Urrutia R. Key role of Krüppel-like factor proteins in pancreatic cancer and other gastrointestinal neoplasias. Current Opinion in Gastroenterology. 22: 505-11. PMID 16891881 DOI: 10.1097/01.Mog.0000239864.73962.Db |
0.399 |
|
| 2006 |
Lomberk G, Bensi D, Fernandez-Zapico ME, Urrutia R. Evidence for the existence of an HP1-mediated subcode within the histone code. Nature Cell Biology. 8: 407-15. PMID 16531993 DOI: 10.1038/Ncb1383 |
0.354 |
|
| 2006 |
Toruner M, Fernandez-Zapico M, Sha JJ, Pham L, Urrutia R, Egan LJ. Antianoikis effect of nuclear factor-kappaB through up-regulated expression of osteoprotegerin, BCL-2, and IAP-1. The Journal of Biological Chemistry. 281: 8686-96. PMID 16407217 DOI: 10.1074/Jbc.M512178200 |
0.368 |
|
| 2006 |
Natesampillai S, Fernandez-Zapico ME, Urrutia R, Veldhuis JD. A novel functional interaction between the Sp1-like protein KLF13 and SREBP-Sp1 activation complex underlies regulation of low density lipoprotein receptor promoter function. The Journal of Biological Chemistry. 281: 3040-7. PMID 16303770 DOI: 10.1074/Jbc.M509417200 |
0.387 |
|
| 2006 |
Tsuji S, Zhang J, Lomberk G, Fernadez-Zapico M, Urrutia R. Isolation Of Wd40 Proteins As Potential Co-Repressors For The Tgf-??-Inducible Tumor Suppressor Gene Klf11 Pancreas. 33: 503-504. DOI: 10.1097/00006676-200611000-00225 |
0.315 |
|
| 2006 |
Truty MJ, Tsuji S, Lomberk G, Fernandez-Zapico M, Urrutia R. Klf14: A Novel Sp/Klf Transcriptional Repressor Of The Type Ii Tgf-?? Receptor In Pancreatic Cancer Leading To Gene Silencing Pancreas. 33: 503. DOI: 10.1097/00006676-200611000-00223 |
0.36 |
|
| 2005 |
Lomberk G, Urrutia R. The family feud: turning off Sp1 by Sp1-like KLF proteins Biochemical Journal. 392: 1-11. PMID 16266294 DOI: 10.1042/Bj20051234 |
0.36 |
|
| 2005 |
Lomberk G, Fernandez-Zapico ME, Urrutia R. When developmental signaling pathways go wrong and their impact on pancreatic cancer development. Current Opinion in Gastroenterology. 21: 555-60. PMID 16093769 DOI: 10.1097/01.Mog.0000175462.38153.F7 |
0.338 |
|
| 2005 |
Ougolkov AV, Fernandez-Zapico ME, Savoy DN, Urrutia RA, Billadeau DD. Glycogen synthase kinase-3beta participates in nuclear factor kappaB-mediated gene transcription and cell survival in pancreatic cancer cells. Cancer Research. 65: 2076-81. PMID 15781615 DOI: 10.1158/0008-5472.Can-04-3642 |
0.336 |
|
| 2005 |
Neve B, Fernandez-Zapico ME, Ashkenazi-Katalan V, Dina C, Hamid YH, Joly E, Vaillant E, Benmezroua Y, Durand E, Bakaher N, Delannoy V, Vaxillaire M, Cook T, Dallinga-Thie GM, Jansen H, ... ... Urrutia R, et al. Role of transcription factor KLF11 and its diabetes-associated gene variants in pancreatic beta cell function. Proceedings of the National Academy of Sciences of the United States of America. 102: 4807-12. PMID 15774581 DOI: 10.1073/Pnas.0409177102 |
0.36 |
|
| 2005 |
Fernandez-Zapico ME, Gonzalez-Paz NC, Weiss E, Savoy DN, Molina JR, Fonseca R, Smyrk TC, Chari ST, Urrutia R, Billadeau DD. Ectopic expression of VAV1 reveals an unexpected role in pancreatic cancer tumorigenesis. Cancer Cell. 7: 39-49. PMID 15652748 DOI: 10.1016/J.Ccr.2004.11.024 |
0.408 |
|
| 2005 |
Cao S, Fernandez-Zapico ME, Jin D, Puri V, Cook TA, Lerman LO, Zhu XY, Urrutia R, Shah V. KLF11-mediated repression antagonizes Sp1/sterol-responsive element-binding protein-induced transcriptional activation of caveolin-1 in response to cholesterol signaling. The Journal of Biological Chemistry. 280: 1901-10. PMID 15531587 DOI: 10.1074/Jbc.M407941200 |
0.381 |
|
| 2005 |
Truty MJ, Fernandez-Zapico ME, Urrutia R. Comprehensive Analysis Of The Sp/Klf Family Of Transcription Factors In The Tgf-Beta Signaling In Pancreatic Cancer Cells Pancreas. 31: 474. DOI: 10.1097/01.Mpa.0000193781.42217.51 |
0.342 |
|
| 2005 |
Ougolkov AV, Savoy DN, Fernandez-Zapico ME, Urrutia R, Smyrk TC, Chari ST, Billadeau DD. NUCLEAR ACCUMULATION OF ACTIVE GSK-3?? CONTRIBUTES TO NF??B-MEDIATED PANCREATIC CANCER CELL SURVIVAL AND PROLIFERATION Pancreas. 31: 461. DOI: 10.1097/01.Mpa.0000193736.49910.78 |
0.339 |
|
| 2005 |
Fernandez-Zapico ME, Tsuji S, Urrutia R. Global Functional Analysis Of Sp/Klf Proteins Identify Klf11 As Novel Tumor Suppressor Candidate For Pancreatic Cancer Pancreas. 31: 441. DOI: 10.1097/01.Mpa.0000193667.32396.85 |
0.355 |
|
| 2004 |
Ellenrieder V, Buck A, Harth A, Jungert K, Buchholz M, Adler G, Urrutia R, Gress TM. KLF11 mediates a critical mechanism in TGF-beta signaling that is inactivated by Erk-MAPK in pancreatic cancer cells. Gastroenterology. 127: 607-20. PMID 15300592 DOI: 10.1053/J.Gastro.2004.05.018 |
0.39 |
|
| 2004 |
Lomberk G, Bensi D, Urrutia R. REGULATION OF THE CHROMATIN PROTEIN HP1γ BY THE MITOTIC AURORA ONCOPROTEINS. Pancreas. 29: 356. DOI: 10.1097/00006676-200411000-00118 |
0.354 |
|
| 2004 |
Lomberk G, Bensi D, Urrutia R. HP1γ, A REGULATOR OF EPIGENETIC GENE SILENCING BY DNA METHYLATION, IS REGULATED BY CHANGES IN NUCLEAR LOCALIZATION IN RESPONSE TO PHOSPHORYLATION. Pancreas. 29: 356. DOI: 10.1097/00006676-200411000-00117 |
0.337 |
|
| 2004 |
Fernandez-Zapico ME, Urrutia R. Molecular pathways of pancreatic carcinogenesis Drug Discovery Today: Disease Mechanisms. 1: 247-252. DOI: 10.1016/J.Ddmec.2004.09.003 |
0.356 |
|
| 2003 |
Fernandez-Zapico ME, Callahan G, Delgado S, Urrutia R. Expression profiling in pancreatic cancer research: the initial steps and the road ahead. Current Opinion in Gastroenterology. 19: 467-72. PMID 15703590 DOI: 10.1097/00001574-200309000-00005 |
0.323 |
|
| 2003 |
Urrutia R. KRAB-containing zinc-finger repressor proteins Genome Biology. 4: 231-231. PMID 14519192 DOI: 10.1186/Gb-2003-4-10-231 |
0.332 |
|
| 2003 |
Fernandez-Zapico ME, Mladek A, Ellenrieder V, Folch-Puy E, Miller L, Urrutia R. An mSin3A interaction domain links the transcriptional activity of KLF11 with its role in growth regulation. The Embo Journal. 22: 4748-58. PMID 12970187 DOI: 10.1093/Emboj/Cdg470 |
0.418 |
|
| 2003 |
Fernandez-Zapico ME, Bramati PS, Zakaria S, Kaczynski JA, Urrutia R. Fundamentals of transcription factors and their impact on pancreatic development and cancer. Pancreatology : Official Journal of the International Association of Pancreatology (Iap) ... [Et Al.]. 3: 276-83. PMID 12890989 DOI: 10.1159/000071765 |
0.393 |
|
| 2003 |
Zhang M, Kalinec GM, Urrutia R, Billadeau DD, Kalinec F. ROCK-dependent and ROCK-independent control of cochlear outer hair cell electromotility. The Journal of Biological Chemistry. 278: 35644-50. PMID 12837763 DOI: 10.1074/Jbc.M301668200 |
0.353 |
|
| 2003 |
Kaczynski J, Cook T, Urrutia R. Sp1- and Krüppel-like transcription factors. Genome Biology. 4: 206. PMID 12620113 DOI: 10.1186/Gb-2003-4-2-206 |
0.393 |
|
| 2003 |
Callahan G, Delgado S, Urrutia R. Regulatory mechanisms of position effect variegation in pancreatic epithelial cancer cells by HP1 isoform modifications Gastroenterology. 124. DOI: 10.1016/S0016-5085(03)81765-1 |
0.377 |
|
| 2002 |
Fernandez-Zapico ME, Kaczynski JA, Urrutia R. Pancreatic cancer research: challenges, opportunities, and recent developments. Current Opinion in Gastroenterology. 18: 563-7. PMID 17033334 DOI: 10.1097/00001574-200209000-00007 |
0.309 |
|
| 2002 |
Urrutia R. Emerging cellular and molecular themes in pancreatic cancer research International Journal of Gastrointestinal Cancer. 31: 1-4. PMID 12622409 DOI: 10.1385/Ijgc:31:1-3:1 |
0.312 |
|
| 2002 |
Kaczynski JA, Conley AA, Zapico MF, Delgado SM, Zhang JS, Urrutia R. Functional analysis of basic transcription element (BTE)-binding protein (BTEB) 3 and BTEB4, a novel Sp1-like protein, reveals a subfamily of transcriptional repressors for the BTE site of the cytochrome P4501A1 gene promoter. Biochemical Journal. 366: 873-882. PMID 12036432 DOI: 10.1042/Bj20020388 |
0.376 |
|
| 2002 |
Ellenrieder V, Zhang JS, Kaczynski J, Urrutia R. Signaling disrupts mSin3A binding to the Mad1-like Sin3-interacting domain of TIEG2, an Sp1-like repressor. The Embo Journal. 21: 2451-2460. PMID 12006497 DOI: 10.1093/Emboj/21.10.2451 |
0.356 |
|
| 2002 |
Cook T, Mesa K, Urrutia R. Three Dynamin‐Encoding Genes Are Differentially Expressed in Developing Rat Brain Journal of Neurochemistry. 67: 927-931. PMID 8752097 DOI: 10.1046/J.1471-4159.1996.67030927.X |
0.313 |
|
| 2001 |
Ellenrieder V, Fernandez Zapico ME, Urrutia R. TGFbeta-mediated signaling and transcriptional regulation in pancreatic development and cancer. Current Opinion in Gastroenterology. 17: 434-40. PMID 17031197 DOI: 10.1097/00001574-200109000-00006 |
0.444 |
|
| 2001 |
Fernandez Zapico ME, Ahmad US, Urrutia R. DNA microarrays: revolutionary insight into the living genome. Surgery. 130: 403-7. PMID 11562660 DOI: 10.1067/Msy.2001.112635 |
0.315 |
|
| 2001 |
Kaczynski J, Zhang JS, Ellenrieder V, Conley A, Duenes T, Kester H, Burg BVd, Urrutia R. The Sp1-like protein BTEB3 inhibits transcription via the basic transcription element box by interacting with mSin3A and HDAC-1 co-repressors and competing with Sp1. Journal of Biological Chemistry. 276: 36749-36756. PMID 11477107 DOI: 10.1074/Jbc.M105831200 |
0.365 |
|
| 2001 |
Zhang J, Moncrieffe MC, Kaczynski J, Ellenrieder V, Prendergast FG, Urrutia R. A Conserved α-Helical Motif Mediates the Interaction of Sp1-Like Transcriptional Repressors with the Corepressor mSin3A Molecular and Cellular Biology. 21: 5041-5049. PMID 11438660 DOI: 10.1128/Mcb.21.15.5041-5049.2001 |
0.361 |
|
| 2001 |
Gebelein B, Urrutia R. Sequence-specific transcriptional repression by KS1, a multiple-zinc-finger-Krüppel-associated box protein. Molecular and Cellular Biology. 21: 928-39. PMID 11154279 DOI: 10.1128/Mcb.21.3.928-939.2001 |
0.344 |
|
| 2001 |
Ellenrieder V, Zhang J, Kaczynski J, Urrutia R. The activity of the TGFβ-inducible transcription factor TIEG2 is antagonized by the proliferative EGFR-MEK-ERK signaling pathway Gastroenterology. 120. DOI: 10.1016/S0016-5085(08)82467-5 |
0.302 |
|
| 2001 |
Conley A, Kaczynski J, Ellenrieder V, Urrutia R. Four different Sp1-like proteins bind to the BTE box element present in the promoter of the carcinogen encoding enzyme P4501A1 gene Gastroenterology. 120. DOI: 10.1016/S0016-5085(08)81692-7 |
0.313 |
|
| 2001 |
Kaczynski J, Zhang J, Stroope A, Urrutia R. A novel mechanism for the regulation of the carcinogen-metabolizing enzyme CYP1A1 gene promoter in pancreatic cells* Gastroenterology. 120. DOI: 10.1016/S0016-5085(08)81688-5 |
0.373 |
|
| 2001 |
Zhang J, Moncrieffe M, Kaczynski J, Prendergast F, Urrutia R. Molecular mechanisms of transcriptional repression shared by the growth regulatory Sp1-like proteins and the tumor suppressor Mad1 Gastroenterology. 120. DOI: 10.1016/S0016-5085(08)80685-3 |
0.344 |
|
| 2001 |
Zapico MF, Mladek a, Wilson T, Ellenrieder V, Wille A, Urrutia R. Identification of genes differentially expressed in mice that are overexpressing the TGF β-inducible transcription factor TIEG2 by microarray hybridization Gastroenterology. 120. DOI: 10.1016/S0016-5085(08)80649-X |
0.312 |
|
| 2000 |
Kalinec F, Zhang M, Urrutia R, Kalinec G. Rho GTPases mediate the regulation of cochlear outer hair cell motility by acetylcholine. Journal of Biological Chemistry. 275: 28000-28005. PMID 10862776 DOI: 10.1074/Jbc.M004917200 |
0.337 |
|
| 2000 |
Cook T, Urrutia R. TIEG proteins join the Smads as TGF-β-regulated transcription factors that control pancreatic cell growth American Journal of Physiology-Gastrointestinal and Liver Physiology. 278. PMID 10762604 DOI: 10.1152/Ajpgi.2000.278.4.G513 |
0.403 |
|
| 2000 |
Kaczynski JA, Urrutia R. BTEB3, a novel Sp1-like protein represses gene expression by a dual mechanism: Direct repression and competition with the activator Sp1 Gastroenterology. 118. DOI: 10.1016/S0016-5085(00)84696-X |
0.338 |
|
| 2000 |
Gebelein BA, Urrutia R. KS1, a novel suppressor of neoplastic transformation, represses transcription through interactions with the KAP1 co-repressor protein Gastroenterology. 118. DOI: 10.1016/S0016-5085(00)84694-6 |
0.322 |
|
| 1999 |
Cook T, Gebelein B, Belal M, Mesa K, Urrutia R. Three conserved transcriptional repressor domains are a defining feature of the TIEG subfamily of Sp1-like zinc finger proteins. The Journal of Biological Chemistry. 274: 29500-4. PMID 10506214 DOI: 10.1074/Jbc.274.41.29500 |
0.311 |
|
| 1999 |
Cook T, Gebelein B, Urrutia R. Sp1 and its likes: biochemical and functional predictions for a growing family of zinc finger transcription factors. Annals of the New York Academy of Sciences. 880: 94-102. PMID 10415854 DOI: 10.1111/J.1749-6632.1999.Tb09513.X |
0.395 |
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| 1998 |
Gebelein B, Fernandez-Zapico M, Imoto M, Urrutia R. KRAB-independent suppression of neoplastic cell growth by the novel zinc finger transcription factor KS1. The Journal of Clinical Investigation. 102: 1911-9. PMID 9835615 DOI: 10.1172/Jci1919 |
0.368 |
|
| 1998 |
Zhang JS, Nelson M, Wang L, Liu W, Qian CP, Shridhar V, Urrutia R, Smith DI. Identification and chromosomal localization of CTNNAL1, a novel protein homologous to α-catenin Genomics. 54: 149-154. PMID 9806841 DOI: 10.1006/Geno.1998.5458 |
0.362 |
|
| 1998 |
Cook T, Gebelein B, Mesa K, Mladek A, Urrutia R. Molecular cloning and characterization of TIEG2 reveals a new subfamily of transforming growth factor-beta-inducible Sp1-like zinc finger-encoding genes involved in the regulation of cell growth. The Journal of Biological Chemistry. 273: 25929-36. PMID 9748269 DOI: 10.1074/Jbc.273.40.25929 |
0.385 |
|
| 1998 |
Urrutia R, Miller LJ, DiMagno EP. 1996 Comfort Symposium on pancreatic carcinogenesis Pancreas. 16: 1-5. PMID 9436855 DOI: 10.1097/00006676-199801000-00001 |
0.371 |
|
| 1998 |
Urrutia R, Miller LJ. Novel membrane-to-nucleus pathways in the regulation of pancreatic acinar cell function Current Opinion in Gastroenterology. 14: 369-375. DOI: 10.1097/00001574-199809000-00003 |
0.343 |
|
| 1998 |
Gebelein B, Zapico MF, Urrutia R. Exocrine pancreatic cells express a novel family of KRAB/ID zinc finger transcriptional repressors involved in growth regulation Gastroenterology. 114. DOI: 10.1016/S0016-5085(98)82446-3 |
0.384 |
|
| 1998 |
Cook T, Tuma A, Urrutia R. Regulation of epithelial cell growth by the pancreas-enriched zinc finger transcription factor, PKLF Gastroenterology. 114: A581. DOI: 10.1016/S0016-5085(98)82366-4 |
0.367 |
|
| 1998 |
Cook T, Tachibana I, Mesa K, Imoto M, Gebelein B, Tuma A, Urrutia R. Characterization of a highly related family of SP1-like transcriptional repressor proteins from pancreatic epithelial cell populations Gastroenterology. 114: A581. DOI: 10.1016/S0016-5085(98)82365-2 |
0.352 |
|
| 1997 |
Urrutia R. Exploring the role of homeobox and zinc finger proteins in pancreatic cell proliferation, differentiation, and apoptosis. International Journal of Pancreatology. 22: 1-14. PMID 9387019 DOI: 10.1007/Bf02803899 |
0.435 |
|
| 1997 |
Tachibana I, Imoto M, Adjei PN, Gores GJ, Subramaniam M, Spelsberg TC, Urrutia R. Overexpression of the TGFbeta-regulated zinc finger encoding gene, TIEG, induces apoptosis in pancreatic epithelial cells. Journal of Clinical Investigation. 99: 2365-2374. PMID 9153278 DOI: 10.1172/Jci119418 |
0.411 |
|
| 1997 |
Urrutia R, Henley JR, Cook T, McNiven MA. The dynamins: redundant or distinct functions for an expanding family of related GTPases? Proceedings of the National Academy of Sciences of the United States of America. 94: 377-84. PMID 9012790 DOI: 10.1073/Pnas.94.2.377 |
0.336 |
|
| 1996 |
Cook TA, Mesa KJ, Gebelein BA, Urrutia RA. Upregulation of dynamin II expression during the acquisition of a mature pancreatic acinar cell phenotype. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 44: 1373-8. PMID 8985129 DOI: 10.1177/44.12.8985129 |
0.382 |
|
| 1996 |
Gebelein B, Mesa K, Urrutia R. A novel profile of expressed sequence tags for zinc finger encoding genes from the poorly differentiated exocrine pancreatic cell line AR4IP. Cancer Letters. 105: 225-31. PMID 8697448 DOI: 10.1016/0304-3835(96)04286-3 |
0.402 |
|
| 1996 |
Török N, Urrutia R, Nakamura T, McNiven MA. Upregulation of molecular motor-encoding genes during hepatocyte growth factor- and epidermal growth factor-induced cell motility. Journal of Cellular Physiology. 167: 422-33. PMID 8655596 DOI: 10.1002/(Sici)1097-4652(199606)167:3<422::Aid-Jcp6>3.0.Co;2-R |
0.3 |
|
| 1996 |
Mesa K, Gebelein B, Cook T, Urrutia R. Identification and characterization of zinc finger encoding genes from the tumoral exocrine pancreatic cell line AR42J. Cancer Letters. 103: 143-9. PMID 8635150 DOI: 10.1016/0304-3835(96)04204-8 |
0.422 |
|
| 1996 |
Valentich MA, Cook T, Urrutia R. Expression of dynamin immunoreactivity in experimental pancreatic tumors induced in rat by mancozeb-nitrosomethylurea Cancer Letters. 102: 23-29. PMID 8603375 DOI: 10.1016/0304-3835(96)04162-6 |
0.375 |
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