Anna A. DePaoli-Roach - Publications

Affiliations: 
Indiana University, Bloomington, Bloomington, IN, United States 
Area:
Biochemistry

125 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Ullman JC, Mellem KT, Xi Y, Ramanan V, Merritt H, Choy R, Gujral T, Young LEA, Blake K, Tep S, Homburger JR, O'Regan A, Ganesh S, Wong P, Satterfield TF, ... ... DePaoli-Roach AA, et al. Small-molecule inhibition of glycogen synthase 1 for the treatment of Pompe disease and other glycogen storage disorders. Science Translational Medicine. 16: eadf1691. PMID 38232139 DOI: 10.1126/scitranslmed.adf1691  0.696
2022 Fastman NM, Liu Y, Ramanan V, Merritt H, Ambing E, DePaoli-Roach AA, Roach PJ, Hurley TD, Mellem KT, Ullman JC, Green E, Morgans D, Tzitzilonis C. The structural mechanism of human glycogen synthesis by the GYS1-GYG1 complex. Cell Reports. 40: 111041. PMID 35793618 DOI: 10.1016/j.celrep.2022.111041  0.691
2021 Sun RC, Young LEA, Bruntz RC, Markussen KH, Zhou Z, Conroy LR, Hawkinson TR, Clarke HA, Stanback AE, Macedo JKA, Emanuelle S, Brewer MK, Rondon AL, Mestas A, Sanders WC, ... ... DePaoli-Roach AA, et al. Brain glycogen serves as a critical glucosamine cache required for protein glycosylation. Cell Metabolism. PMID 34043942 DOI: 10.1016/j.cmet.2021.05.003  0.666
2020 Chown EE, Wang P, Zhao X, Crowder JJ, Strober JW, Sullivan MA, Xue Y, Bennett CS, Perri AM, Evers BM, Roach PJ, Depaoli-Roach AA, Akman HO, Pederson BA, Minassian BA. GYS1 or PPP1R3C deficiency rescues murine adult polyglucosan body disease. Annals of Clinical and Translational Neurology. PMID 33034425 DOI: 10.1002/acn3.51211  0.467
2020 Tang B, Frasinyuk MS, Chikwana VM, Mahalingan KK, Morgan CA, Segvich DM, Bondarenko SP, Mrug GP, Wyrebek P, Watt DS, DePaoli-Roach AA, Roach PJ, Hurley TD. Discovery and development of small-molecule inhibitors of glycogen synthase. Journal of Medicinal Chemistry. PMID 32134266 DOI: 10.1021/acs.jmedchem.9b01851  0.692
2020 Young LEA, Brizzee CO, Macedo JKA, Murphy RD, Contreras CJ, DePaoli-Roach AA, Roach PJ, Gentry MS, Sun RC. Accurate and sensitive quantitation of glucose and glucose phosphates derived from storage carbohydrates by mass spectrometry. Carbohydrate Polymers. 230: 115651. PMID 31887930 DOI: 10.1016/J.Carbpol.2019.115651  0.586
2019 Brewer MK, Uittenbogaard A, Austin GL, Segvich DM, DePaoli-Roach A, Roach PJ, McCarthy JJ, Simmons ZR, Brandon JA, Zhou Z, Zeller J, Young LEA, Sun RC, Pauly JR, Aziz NM, et al. Targeting Pathogenic Lafora Bodies in Lafora Disease Using an Antibody-Enzyme Fusion. Cell Metabolism. PMID 31353261 DOI: 10.1016/J.Cmet.2019.07.002  0.548
2019 Burlet-Godinot S, Petit J-, Roach PJ, Depaoli-Roach AA, Magistretti PJ. New insights into the “Glycogenetic” hypothesis of sleep: brain glycogen availability affects REM-related theta rhythm providing a possible link with emotional memory mechanisms Sleep Medicine. 64. DOI: 10.1016/J.Sleep.2019.11.841  0.465
2017 Irimia JM, Meyer CM, Segvich DM, Surendran S, DePaoli-Roach AA, Morral N, Roach PJ. Lack of liver glycogen causes hepatic insulin resistance and Steatosis in mice. The Journal of Biological Chemistry. PMID 28483921 DOI: 10.1074/Jbc.M117.786525  0.525
2017 Skurat AV, Segvich D, DePaoli-Roach AA, Roach PJ. NOVEL METHOD FOR DETECTION OF GLYCOGEN IN CELLS. Glycobiology. PMID 28077463 DOI: 10.1093/Glycob/Cwx005  0.561
2017 Burlet-Godinot S, Allaman I, Grenningloh G, Roach P, Depaoli-Roach A, Magistretti P, Petit J. Functional consequences of brain glycogen deficiency on the sleep-wake cycle regulation in PTG-KO mice Sleep Medicine. 40: e43-e44. DOI: 10.1016/J.Sleep.2017.11.121  0.488
2016 Ruchti E, Roach PJ, DePaoli-Roach AA, Magistretti PJ, Allaman I. Protein targeting to glycogen is a master regulator of glycogen synthesis in astrocytes Ibro Reports. 1: 46-53. PMID 30135927 DOI: 10.1016/J.Ibror.2016.10.002  0.571
2016 Mahalingan KK, Baskaran S, Depaoli-Roach AA, Roach PJ, Hurley TD. Redox switch for the inhibited state of yeast glycogen synthase mimics regulation by phosphorylation. Biochemistry. PMID 27935293 DOI: 10.1021/Acs.Biochem.6B00884  0.76
2016 Contreras CJ, Segvich DM, Mahalingan K, Chikwana VM, Kirley TL, Hurley TD, DePaoli-Roach AA, Roach PJ. Incorporation of phosphate into glycogen by glycogen synthase. Archives of Biochemistry and Biophysics. PMID 27036853 DOI: 10.1016/J.Abb.2016.03.020  0.707
2015 Irimia JM, Tagliabracci VS, Meyer CM, Segvich DM, DePaoli-Roach AA, Roach PJ. Muscle Glycogen Remodeling and Glycogen Phosphate Metabolism following Exhaustive Exercise of Wild Type and Laforin Knockout Mice. The Journal of Biological Chemistry. 290: 22686-98. PMID 26216881 DOI: 10.1074/Jbc.M115.673897  0.577
2015 DePaoli-Roach AA, Contreras CJ, Segvich DM, Heiss C, Ishihara M, Azadi P, Roach PJ. Glycogen phosphomonoester distribution in mouse models of the progressive myoclonic epilepsy, Lafora disease. The Journal of Biological Chemistry. 290: 841-50. PMID 25416783 DOI: 10.1074/Jbc.M114.607796  0.594
2015 Chikwana VM, Khanna M, Baskaran S, Tagliabracci VS, Contreras CJ, DePaoli-Roach A, Roach PJ, Hurley TD. Correction: Structural basis for 2′-phosphate incorporation into glycogen by glycogen synthase (Proceedings of the National Academy of Sciences of the United States of America (2013) 110, 52 (20976-20981) DOI: 10.1073/pnas.1310106111) Proceedings of the National Academy of Sciences of the United States of America. 112: E2264. DOI: 10.1073/Pnas.1506041112  0.724
2014 Garyali P, Segvich DM, DePaoli-Roach AA, Roach PJ. Protein degradation and quality control in cells from laforin and malin knockout mice. The Journal of Biological Chemistry. 289: 20606-14. PMID 24914213 DOI: 10.1074/Jbc.M114.580167  0.528
2014 Ruiz R, Jideonwo V, Ahn M, Surendran S, Tagliabracci VS, Hou Y, Gamble A, Kerner J, Irimia-Dominguez JM, Puchowicz MA, DePaoli-Roach A, Hoppel C, Roach P, Morral N. Sterol regulatory element-binding protein-1 (SREBP-1) is required to regulate glycogen synthesis and gluconeogenic gene expression in mouse liver. The Journal of Biological Chemistry. 289: 5510-7. PMID 24398675 DOI: 10.1074/Jbc.M113.541110  0.549
2013 Chikwana VM, Khanna M, Baskaran S, Tagliabracci VS, Contreras CJ, DePaoli-Roach A, Roach PJ, Hurley TD. Structural basis for 2'-phosphate incorporation into glycogen by glycogen synthase. Proceedings of the National Academy of Sciences of the United States of America. 110: 20976-81. PMID 24324135 DOI: 10.1073/Pnas.1310106111  0.758
2013 Roach PJ, Depaoli-Roach AA. Glycogen metabolism and lafora disease Protein Tyrosine Phosphatase Control of Metabolism. 239-262. DOI: 10.1007/978-1-4614-7855-3_13  0.454
2012 Roach PJ, Depaoli-Roach AA, Hurley TD, Tagliabracci VS. Glycogen and its metabolism: some new developments and old themes. The Biochemical Journal. 441: 763-87. PMID 22248338 DOI: 10.1042/Bj20111416  0.703
2012 DePaoli-Roach AA, Segvich DM, Meyer CM, Rahimi Y, Worby CA, Gentry MS, Roach PJ. Laforin and malin knockout mice have normal glucose disposal and insulin sensitivity. Human Molecular Genetics. 21: 1604-10. PMID 22186021 DOI: 10.1093/Hmg/Ddr598  0.58
2011 Baskaran S, Chikwana VM, Contreras CJ, Davis KD, Wilson WA, DePaoli-Roach AA, Roach PJ, Hurley TD. Multiple glycogen-binding sites in eukaryotic glycogen synthase are required for high catalytic efficiency toward glycogen. The Journal of Biological Chemistry. 286: 33999-4006. PMID 21835915 DOI: 10.1074/Jbc.M111.264531  0.736
2011 Turnbull J, DePaoli-Roach AA, Zhao X, Cortez MA, Pencea N, Tiberia E, Piliguian M, Roach PJ, Wang P, Ackerley CA, Minassian BA. PTG depletion removes Lafora bodies and rescues the fatal epilepsy of Lafora disease. Plos Genetics. 7: e1002037. PMID 21552327 DOI: 10.1371/Journal.Pgen.1002037  0.532
2011 Tagliabracci VS, Heiss C, Karthik C, Contreras CJ, Glushka J, Ishihara M, Azadi P, Hurley TD, DePaoli-Roach AA, Roach PJ. Phosphate incorporation during glycogen synthesis and Lafora disease. Cell Metabolism. 13: 274-82. PMID 21356517 DOI: 10.1016/J.Cmet.2011.01.017  0.728
2011 Jiang S, Heller B, Tagliabracci VS, Zhai L, Irimia JM, DePaoli-Roach AA, Wells CD, Skurat AV, Roach PJ. Starch binding domain-containing protein 1/genethonin 1 is a novel participant in glycogen metabolism (Journal of Biological Chemistry (2010) 285, (34960-34971)) Journal of Biological Chemistry. 286: 39673. DOI: 10.1074/Jbc.A110.150839  0.53
2010 Baskaran S, Roach PJ, DePaoli-Roach AA, Hurley TD. Structural basis for glucose-6-phosphate activation of glycogen synthase. Proceedings of the National Academy of Sciences of the United States of America. 107: 17563-8. PMID 20876143 DOI: 10.1073/Pnas.1006340107  0.797
2010 Jiang S, Heller B, Tagliabracci VS, Zhai L, Irimia JM, DePaoli-Roach AA, Wells CD, Skurat AV, Roach PJ. Starch binding domain-containing protein 1/genethonin 1 is a novel participant in glycogen metabolism. The Journal of Biological Chemistry. 285: 34960-71. PMID 20810658 DOI: 10.1074/Jbc.M110.150839  0.581
2010 DePaoli-Roach AA, Tagliabracci VS, Segvich DM, Meyer CM, Irimia JM, Roach PJ. Genetic depletion of the malin E3 ubiquitin ligase in mice leads to lafora bodies and the accumulation of insoluble laforin. The Journal of Biological Chemistry. 285: 25372-81. PMID 20538597 DOI: 10.1074/Jbc.M110.148668  0.592
2010 Irimia JM, Meyer CM, Peper CL, Zhai L, Bock CB, Previs SF, McGuinness OP, DePaoli-Roach A, Roach PJ. Impaired glucose tolerance and predisposition to the fasted state in liver glycogen synthase knock-out mice. The Journal of Biological Chemistry. 285: 12851-61. PMID 20178984 DOI: 10.1074/Jbc.M110.106534  0.574
2010 DePaoli-Roach AA. Protein Phosphatase 1 Binding Proteins Handbook of Cell Signaling, 2/E. 2: 689-697. DOI: 10.1016/B978-0-12-374145-5.00088-7  0.317
2009 Eckerdt F, Pascreau G, Phistry M, Lewellyn AL, DePaoli-Roach AA, Maller JL. Phosphorylation of TPX2 by Plx1 enhances activation of Aurora A. Cell Cycle (Georgetown, Tex.). 8: 2413-9. PMID 19556869 DOI: 10.4161/Cc.8.15.9086  0.418
2008 Tagliabracci VS, Girard JM, Segvich D, Meyer C, Turnbull J, Zhao X, Minassian BA, Depaoli-Roach AA, Roach PJ. Abnormal metabolism of glycogen phosphate as a cause for Lafora disease. The Journal of Biological Chemistry. 283: 33816-25. PMID 18852261 DOI: 10.1074/Jbc.M807428200  0.632
2008 Savage DB, Zhai L, Ravikumar B, Choi CS, Snaar JE, McGuire AC, Wou SE, Medina-Gomez G, Kim S, Bock CB, Segvich DM, Solanky B, Deelchand D, Vidal-Puig A, Wareham NJ, ... ... DePaoli-Roach AA, et al. A prevalent variant in PPP1R3A impairs glycogen synthesis and reduces muscle glycogen content in humans and mice. Plos Medicine. 5: e27. PMID 18232732 DOI: 10.1371/Journal.Pmed.0050027  0.559
2007 Tagliabracci VS, Turnbull J, Wang W, Girard JM, Zhao X, Skurat AV, Delgado-Escueta AV, Minassian BA, Depaoli-Roach AA, Roach PJ. Laforin is a glycogen phosphatase, deficiency of which leads to elevated phosphorylation of glycogen in vivo. Proceedings of the National Academy of Sciences of the United States of America. 104: 19262-6. PMID 18040046 DOI: 10.1073/Pnas.0707952104  0.625
2007 Hurley TD, Yang J, Zhang L, Goodwin KD, Zou Q, Cortese M, Dunker AK, DePaoli-Roach AA. Structural basis for regulation of protein phosphatase 1 by inhibitor-2. The Journal of Biological Chemistry. 282: 28874-83. PMID 17636256 DOI: 10.1074/Jbc.M703472200  0.626
2007 Wang W, Lohi H, Skurat AV, DePaoli-Roach AA, Minassian BA, Roach PJ. Glycogen metabolism in tissues from a mouse model of Lafora disease. Archives of Biochemistry and Biophysics. 457: 264-9. PMID 17118331 DOI: 10.1016/J.Abb.2006.10.017  0.627
2006 Wang W, Parker GE, Skurat AV, Raben N, DePaoli-Roach AA, Roach PJ. Relationship between glycogen accumulation and the laforin dual specificity phosphatase. Biochemical and Biophysical Research Communications. 350: 588-92. PMID 17022935 DOI: 10.1016/J.Bbrc.2006.09.091  0.602
2006 Jeoung NH, Wu P, Joshi MA, Jaskiewicz J, Bock CB, Depaoli-Roach AA, Harris RA. Role of pyruvate dehydrogenase kinase isoenzyme 4 (PDHK4) in glucose homoeostasis during starvation. The Biochemical Journal. 397: 417-25. PMID 16606348 DOI: 10.1042/Bj20060125  0.393
2005 Pederson BA, Schroeder JM, Parker GE, Smith MW, DePaoli-Roach AA, Roach PJ. Glucose metabolism in mice lacking muscle glycogen synthase. Diabetes. 54: 3466-73. PMID 16306363 DOI: 10.2337/Diabetes.54.12.3466  0.603
2005 Kirchhefer U, Baba HA, Bokník P, Breeden KM, Mavila N, Brüchert N, Justus I, Matus M, Schmitz W, Depaoli-Roach AA, Neumann J. Enhanced cardiac function in mice overexpressing protein phosphatase Inhibitor-2. Cardiovascular Research. 68: 98-108. PMID 15975567 DOI: 10.1016/J.Cardiores.2005.05.019  0.304
2005 Pederson BA, Cope CR, Irimia JM, Schroeder JM, Thurberg BL, Depaoli-Roach AA, Roach PJ. Mice with elevated muscle glycogen stores do not have improved exercise performance. Biochemical and Biophysical Research Communications. 331: 491-6. PMID 15850786 DOI: 10.1016/J.Bbrc.2005.03.206  0.551
2005 Pathak A, del Monte F, Zhao W, Schultz JE, Lorenz JN, Bodi I, Weiser D, Hahn H, Carr AN, Syed F, Mavila N, Jha L, Qian J, Marreez Y, Chen G, ... ... DePaoli-Roach AA, et al. Enhancement of cardiac function and suppression of heart failure progression by inhibition of protein phosphatase 1. Circulation Research. 96: 756-66. PMID 15746443 DOI: 10.1161/01.Res.0000161256.85833.Fa  0.332
2005 Pederson BA, Cope CR, Schroeder JM, Smith MW, Irimia JM, Thurberg BL, DePaoli-Roach AA, Roach PJ. Exercise capacity of mice genetically lacking muscle glycogen synthase: in mice, muscle glycogen is not essential for exercise. The Journal of Biological Chemistry. 280: 17260-5. PMID 15711014 DOI: 10.1074/Jbc.M410448200  0.544
2004 Pederson BA, Chen H, Schroeder JM, Shou W, DePaoli-Roach AA, Roach PJ. Abnormal cardiac development in the absence of heart glycogen. Molecular and Cellular Biology. 24: 7179-87. PMID 15282316 DOI: 10.1128/Mcb.24.16.7179-7187.2004  0.539
2004 Braz JC, Gregory K, Pathak A, Zhao W, Sahin B, Klevitsky R, Kimball TF, Lorenz JN, Nairn AC, Liggett SB, Bodi I, Wang S, Schwartz A, Lakatta EG, DePaoli-Roach AA, et al. PKC-alpha regulates cardiac contractility and propensity toward heart failure. Nature Medicine. 10: 248-54. PMID 14966518 DOI: 10.1038/Nm1000  0.345
2003 DePaoli-Roach AA, Vilardo PG, Kim JH, Mavila N, Vemuri B, Roach PJ. Determination of mammalian glycogen synthase phosphatase activity. Methods in Enzymology. 366: 17-34. PMID 14674236 DOI: 10.1016/S0076-6879(03)66002-7  0.587
2003 Hurley JH, Zhang S, Bye LS, Marshall MS, DePaoli-Roach AA, Guan K, Fox AP, Yu L. Insulin signaling inhibits the 5-HT2C receptor in choroid plexus via MAP kinase. Bmc Neuroscience. 4: 10. PMID 12795815 DOI: 10.1186/1471-2202-4-10  0.387
2003 Isoda T, Paolocci N, Haghighi K, Wang C, Wang Y, Georgakopoulos D, Servillo G, Della Fazia MA, Kranias EG, Depaoli-Roach AA, Sassone-Corsi P, Kass DA. Novel regulation of cardiac force-frequency relation by CREM (cAMP response element modulator). Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 144-51. PMID 12554693 DOI: 10.1096/Fj.01-0981Com  0.331
2003 DePaoli-Roach AA, Vilardo PG, Kim JH, Mavila N, Vemuri B, Roach PJ. [2] Determination of Mammalian Glycogen Synthase Phosphatase Activity Methods in Enzymology. 366: 17-34. DOI: 10.1016/S0076-6879(03)66002-7  0.531
2002 Carr AN, Schmidt AG, Suzuki Y, del Monte F, Sato Y, Lanner C, Breeden K, Jing SL, Allen PB, Greengard P, Yatani A, Hoit BD, Grupp IL, Hajjar RJ, DePaoli-Roach AA, et al. Type 1 phosphatase, a negative regulator of cardiac function. Molecular and Cellular Biology. 22: 4124-35. PMID 12024026 DOI: 10.1128/Mcb.22.12.4124-4135.2002  0.305
2001 Aschenbach WG, Suzuki Y, Breeden K, Prats C, Hirshman MF, Dufresne SD, Sakamoto K, Vilardo PG, Steele M, Kim JH, Jing SL, Goodyear LJ, DePaoli-Roach AA. The Muscle-specific Protein Phosphatase PP1G/RGL(GM) Is Essential for Activation of Glycogen Synthase by Exercise Journal of Biological Chemistry. 276: 39959-39967. PMID 11522787 DOI: 10.1074/Jbc.M105518200  0.422
2001 Lannér C, Suzuki Y, Bi C, Zhang H, Cooper LD, Bowker-Kinley MM, DePaoli-Roach AA. Gene structure and expression of the targeting subunit, RGL, of the muscle-specific glycogen-associated type 1 protein phosphatase, PP1G Archives of Biochemistry and Biophysics. 388: 135-145. PMID 11361130 DOI: 10.1006/Abbi.2001.2283  0.386
2001 Suzuki Y, Lanner C, Kim JH, Vilardo PG, Zhang H, Yang J, Cooper LD, Steele M, Kennedy A, Bock CB, Scrimgeour A, Lawrence JC, DePaoli-Roach AA. Insulin control of glycogen metabolism in knockout mice lacking the muscle-specific protein phosphatase PP1G/RGL. Molecular and Cellular Biology. 21: 2683-94. PMID 11283248 DOI: 10.1128/Mcb.21.8.2683-2694.2001  0.46
2000 Yang J, Hurley TD, DePaoli-Roach AA. Interaction of inhibitor-2 with the catalytic subunit of type 1 protein phosphatase: Identification of a sequence analogous to the consensus type 1 protein phosphatase-binding motif Journal of Biological Chemistry. 275: 22635-22644. PMID 10807923 DOI: 10.1074/Jbc.M003082200  0.607
2000 Connor JH, Frederick D, Huang Hb, Yang J, Helps NR, Cohen PT, Nairn AC, DePaoli-Roach A, Tatchell K, Shenolikar S. Cellular mechanisms regulating protein phosphatase-1. A key functional interaction between inhibitor-2 and the type 1 protein phosphatase catalytic subunit. The Journal of Biological Chemistry. 275: 18670-5. PMID 10748125 DOI: 10.1074/Jbc.M909312199  0.369
2000 Zhai L, Mu J, Zong H, DePaoli-Roach AA, Roach PJ. Structure and chromosomal localization of the human glycogenin-2 gene GYG2 Gene. 242: 229-235. PMID 10721716 DOI: 10.1016/S0378-1119(99)00520-X  0.492
1999 Hall KU, Collins SP, Gamm DM, Massa E, DePaoli-Roach AA, Uhler MD. Phosphorylation-dependent inhibition of protein phosphatase-1 by G-substrate. A Purkinje cell substrate of the cyclic GMP-dependent protein kinase. The Journal of Biological Chemistry. 274: 3485-95. PMID 9920894 DOI: 10.1074/Jbc.274.6.3485  0.41
1998 Neumann J, Boknik P, DePaoli-Roach AA, Field LJ, Rockman HA, Kobayashi YM, Kelley JS, Jones LR. Targeted overexpression of phospholamban to mouse atrium depresses Ca2+ transport and contractility Journal of Molecular and Cellular Cardiology. 30: 1991-2002. PMID 9799653 DOI: 10.1006/Jmcc.1998.0760  0.323
1997 Zhao Y, Boguslawski G, Zitomer RS, DePaoli-Roach AA. Saccharomyces cerevisiae homologs of mammalian B and B' subunits of protein phosphatase 2A direct the enzyme to distinct cellular functions Journal of Biological Chemistry. 272: 8256-8262. PMID 9079645 DOI: 10.1074/Jbc.272.13.8256  0.333
1997 Komalavilas P, DePaoli-Roach AA, Lincoln TM. The B' γ subunit of protein phosphatase 2A is phosphorylated by cGMP-dependent protein kinase Faseb Journal. 11.  0.344
1996 Daniel S, Zhang S, DePaoli-Roach AA, Kim KH. Dephosphorylation of Sp1 by protein phosphatase 1 is involved in the glucose-mediated activation of the acetyl-CoA carboxylase gene Journal of Biological Chemistry. 271: 14692-14697. PMID 8663083 DOI: 10.1074/Jbc.271.25.14692  0.363
1996 Azpiazu I, Saltiel AR, DePaoli-Roach AA, Lawrence JC. Regulation of both glycogen synthase and PHAS-I by insulin in rat skeletal muscle involves mitogen-activated protein kinase-independent and rapamycin-sensitive pathways Journal of Biological Chemistry. 271: 5033-5039. PMID 8617780 DOI: 10.1074/Jbc.271.9.5033  0.445
1996 Csortos C, Zolnierowicz S, Bakó E, Durbin SD, DePaoli-Roach AA. High complexity in the expression of the B′ subunit of protein phosphatase 2A0: Evidence for the existence of at least seven novel isoforms Journal of Biological Chemistry. 271: 2578-2588. PMID 8576224 DOI: 10.1074/Jbc.271.5.2578  0.32
1995 Zhai L, Graves PR, Robinson LC, Italiano M, Culbertson MR, Rowles J, Cobb MH, DePaoli-Roach AA, Roach PJ. Casein kinase I gamma subfamily. Molecular cloning, expression, and characterization of three mammalian isoforms and complementation of defects in the Saccharomyces cerevisiae YCK genes. The Journal of Biological Chemistry. 270: 12717-24. PMID 7759525 DOI: 10.1074/Jbc.270.21.12717  0.624
1995 Pitcher JA, Payne ES, Csortos C, DePaoli-Roach AA, Lefkowitz RJ. The G-protein-coupled receptor phosphatase: a protein phosphatase type 2A with a distinct subcellular distribution and substrate specificity. Proceedings of the National Academy of Sciences of the United States of America. 92: 8343-7. PMID 7667292 DOI: 10.1073/Pnas.92.18.8343  0.359
1995 Wang QM, Guan KL, Roach PJ, DePaoli-Roach AA. Phosphorylation and activation of the ATP-Mg-dependent protein phosphatase by the mitogen-activated protein kinase Journal of Biological Chemistry. 270: 18352-18358. PMID 7629158 DOI: 10.1074/Jbc.270.31.18352  0.633
1994 Park IK, Roach P, Bondor J, Fox SP, DePaoli-Roach AA. Molecular mechanism of the synergistic phosphorylation of phosphatase inhibitor-2: Cloning, expression, and site-directed mutagenesis of inhibitor-2 Journal of Biological Chemistry. 269: 944-954. PMID 8288648  0.401
1994 Wang QM, Park IK, Fiol CJ, Roach PJ, DePaoli-Roach AA. Isoform differences in substrate recognition by glycogen synthase kinases 3α and 3β in the phosphorylation of phosphatase inhibitor 2 Biochemistry. 33: 143-147. PMID 8286331 DOI: 10.1021/Bi00167A018  0.609
1994 Bollen M, DePaoli-Roach AA, Stalmans W. Native cytosolic protein phosphatase-1 (PP-1S) containing modulator (inhibitor-2) is an active enzyme Febs Letters. 344: 196-200. PMID 8187883 DOI: 10.1016/0014-5793(94)00391-2  0.428
1994 Dutil EM, Keranen LM, DePaoli-Roach AA, Newton AC. In vivo regulation of protein kinase C by trans-phosphorylation followed by autophosphorylation Journal of Biological Chemistry. 269: 29359-29362. PMID 7961910  0.349
1994 Depaoli-Roach AA, Park IK, Cerovsky V, Csortos C, Durbin SD, Kuntz MJ, Sitikov A, Tang PM, Verin A, Zolnierowicz S. Serine/threonine protein phosphatases in the control of cell function Advances in Enzyme Regulation. 34: 199-224. PMID 7942275 DOI: 10.1016/0065-2571(94)90017-5  0.454
1994 Zolnierowicz S, Csortos C, Bondor J, Verin A, Mumby MC, DePaoli-Roach AA. Diversity in the regulatory B-subunits of protein phosphatase 2A: identification of a novel isoform highly expressed in brain. Biochemistry. 33: 11858-67. PMID 7918404 DOI: 10.1021/Bi00205A023  0.304
1994 Wang QM, Fiol CJ, DePaoli-Roach AA, Roach PJ. Glycogen synthase kinase-3β is a dual specificity kinase differentially regulated by tyrosine and serine/threonine phosphorylation Journal of Biological Chemistry. 269: 14566-14574. PMID 7514173  0.607
1993 Graves PR, Haas DW, Hagedorn CH, DePaoli-Roach AA, Roach PJ. Molecular cloning, expression, and characterization of a 49-kilodalton casein kinase I isoform from rat testis Journal of Biological Chemistry. 268: 6394-6401. PMID 8454611  0.579
1993 Cao Y, Skurat AV, DePaoli-Roach AA, Roach PJ. Initiation of glycogen synthesis: Control of glycogenin by glycogen phosphorylase Journal of Biological Chemistry. 268: 21717-21721. PMID 8408025  0.559
1993 Cao Y, Mahrenholz AM, DePaoli-Roach AA, Roach PJ. Characterization of rabbit skeletal muscle glycogenin: Tyrosine 194 is essential for function Journal of Biological Chemistry. 268: 14687-14693. PMID 8325847  0.586
1992 Robinson LC, Hubbard EJ, Graves PR, DePaoli-Roach AA, Roach PJ, Kung C, Haas DW, Hagedorn CH, Goebl M, Culbertson MR. Yeast casein kinase I homologues: an essential gene pair. Proceedings of the National Academy of Sciences of the United States of America. 89: 28-32. PMID 1729698 DOI: 10.1073/Pnas.89.1.28  0.592
1992 Zhai L, Graves PR, Longenecker KL, DePaoli-Roach AA, Roach PJ. Recombinant rabbit muscle casein kinase I α is inhibited by heparin and activated by polylysine Biochemical and Biophysical Research Communications. 189: 944-949. PMID 1472067 DOI: 10.1016/0006-291X(92)92295-9  0.635
1992 Yamanouchi K, Stephens TW, Chikada K, Dominianni SJ, Behforouz H, Scislowski P, DePaoli-Roach A, Allmann DW, Harris RA. Metabolic effects of proglycosyn Archives of Biochemistry and Biophysics. 294: 609-615. PMID 1314546 DOI: 10.1016/0003-9861(92)90732-C  0.349
1992 Viskupic E, Cao Y, Zhang W, Cheng C, DePaoli-Roach AA, Roach PJ. Rabbit skeletal muscle glycogenin: Molecular cloning and production of fully functional protein in Escherichia coli Journal of Biological Chemistry. 267: 25759-25763. PMID 1281472  0.554
1991 Picking WD, Kudlicki W, Kramer G, Hardesty B, Vandenheede JR, Merlevede W, Park IK, DePaoli-Roach A. Fluorescence studies on the interaction of inhibitor 2 and okadaic acid with the catalytic subunit of type 1 phosphoprotein phosphatases. Biochemistry. 30: 10280-7. PMID 1657143 DOI: 10.1021/Bi00106A028  0.375
1991 Roach PJ, Cao Y, Corbett CA, DePaoli-Roach AA, Farkas I, Fiol CJ, Flotow H, Graves PR, Hardy TA, Hrubey TW. Glycogen metabolism and signal transduction in mammals and yeast. Advances in Enzyme Regulation. 31: 101-20. PMID 1652188 DOI: 10.1016/0065-2571(91)90011-A  0.637
1990 Farkas I, Hardy TA, DePaoli-Roach AA, Roach PJ. Isolation of the GSY1 gene encoding yeast glycogen synthase and evidence for the existence of a second gene Journal of Biological Chemistry. 265: 20879-20886. PMID 2123485  0.545
1989 Zhang W, Browner MF, Fletterick RJ, DePaoli-Roach AA, Roach PJ. Primary structure of rabbit skeletal muscle glycogen synthase deduced from cDNA clones Faseb Journal. 3: 2532-2536. PMID 2509275 DOI: 10.1096/Fasebj.3.13.2509275  0.572
1988 Wang Y, Fiol CJ, DePaoli-Roach AA, Bell AW, Hermodson MA, Roach PJ. Identification of phosphorylation sites in peptides using a gas-phase sequencer Analytical Biochemistry. 174: 537-547. PMID 3239755 DOI: 10.1016/0003-2697(88)90053-X  0.481
1988 Mahrenholz AM, Votaw P, Roach PJ, Depaoli-Roach AA, Zioncheck TF, Harrison ML, Geahlen RL. Phosphorylation of glycogen synthase by a bovine thymus protein-tyrosine kinase, p40 Biochemical and Biophysical Research Communications. 155: 52-58. PMID 3137939 DOI: 10.1016/S0006-291X(88)81048-9  0.626
1988 Corvera S, Roach PJ, DePaoli-Roach AA, Czech MP. Insulin action inhibits insulin-like growth factor-II (IGF-II) receptor phosphorylation in H-35 hepatoma cells. IGF-II receptors isolated from insulin-treated cells exhibit enhanced in vitro phosphorylation by casein kinase II Journal of Biological Chemistry. 263: 3116-3122. PMID 2963823  0.521
1988 Fiol CJ, Haseman JH, Wang Y, Roach PJ, Roeske RW, Kowalczuk M, DePaoli-Roach AA. Phosphoserine as a recognition determinant for glycogen synthase kinase-3: Phosphorylation of a synthetic peptide based on the G-component of protein phosphatase-1 Archives of Biochemistry and Biophysics. 267: 797-802. PMID 2850771 DOI: 10.1016/0003-9861(88)90089-6  0.631
1988 Lawrence JC, Hiken J, Burnette B, DePaoli-Roach AA. Phosphorylation of phosphoprotein phosphatase inhibitor-2 (I-2) in rat fat cells Biochemical and Biophysical Research Communications. 150: 197-203. PMID 2827665 DOI: 10.1016/0006-291X(88)90505-0  0.39
1987 Lee FT, Ahmad Z, DePaoli-Roach AA, Roach PJ. Multiple phosphorylation of mouse muscle glycogen synthase Archives of Biochemistry and Biophysics. 258: 615-620. PMID 3118813 DOI: 10.1016/0003-9861(87)90384-5  0.636
1986 DePaoli-Roach A, Roach PJ, Zucker KE, Smith SS. Selective phosphorylation of human DNA methyltransferase by protein kinase C Febs Letters. 197: 149-153. PMID 3949011 DOI: 10.1016/0014-5793(86)80316-7  0.571
1986 Wang Y, Camici M, Lee FT, Ahmad Z, DePaoli-Roach AA, Roach PJ. Multiple phosphorylation sites of rat liver glycogen synthase Bba - Molecular Cell Research. 888: 225-236. PMID 3091084 DOI: 10.1016/0167-4889(86)90025-X  0.661
1986 Corvera S, Davis RJ, Roach PJ, DePaoli-Roach A, Czech MP. Mechanism of receptor kinase action on membrane protein recycling Annals of the New York Academy of Sciences. 488: 419-429. PMID 3034121 DOI: 10.1111/J.1749-6632.1986.Tb54421.X  0.535
1986 Ahmad Z, Lee FT, DePaoli-Roach AA, Roach PJ. Heparin-activated protein kinase from rabbit muscle: Relationship to enzymes of the glycogen synthase kinase-3 category Archives of Biochemistry and Biophysics. 250: 329-335. PMID 3022646 DOI: 10.1016/0003-9861(86)90734-4  0.658
1985 DePaoli-Roach AA, Lee FT. Phosphoprotein phosphatase inhibitor-2 is phosphorylated at both serine and threonine residues in mouse diaphragm Febs Letters. 183: 423-429. PMID 3921407 DOI: 10.1016/0014-5793(85)80824-3  0.437
1985 Haring HU, White MF, Kahn CR, Ahmad Z, DePaoli-Roach AA, Roach PJ. Interaction of the insulin receptor kinase with serine/threonine kinases in vitro Journal of Cellular Biochemistry. 28: 171-182. PMID 3001107 DOI: 10.1002/Jcb.240280209  0.609
1985 Roach P, Roach PJ, DePaoli-Roach AA. Phosphoprotein phosphatase inhibitor-2. Identification as a species of molecular weight 31,000 in rabbit muscle, liver, and other tissues Journal of Biological Chemistry. 260: 6314-6317. PMID 2987219  0.492
1985 Ahmad Z, DePaoli-Roach AA, Roach PJ. Novel heparin-activated protein kinase activity in rabbit skeletal muscle Federation Proceedings. 44. DOI: 10.1016/0014-5793(85)80199-X  0.666
1985 Ahmad Z, DePaoli-Roach AA, Roach PJ. Novel heparin-activated protein kinase activity in rabbit skeletal muscle Federation Proceedings. 44.  0.313
1985 Lee FT, Ahmad Z, DePaoli-Roach AA, Roach PJ. Epinephrine control of multiple phosphorylation sites of glycogen synthase in mouse diaphragms Federation Proceedings. 44.  0.535
1984 Ciudad C, Camici M, Ahmad Z, Wang Y, DePaoli-Roach AA, Roach PJ. Control of glycogen synthase phosphorylation in isolated rat hepatocytes by epinephrine, vasopressin and glucagon European Journal of Biochemistry. 142: 511-520. PMID 6432531 DOI: 10.1111/J.1432-1033.1984.Tb08315.X  0.648
1984 Camici M, DePaoli-Roach AA, Roach PJ. Rabbit liver glycogen synthase. Purification and comparison of the properties of glucose-6-P-dependent and glucose-6-P-independent forms of the enzyme Journal of Biological Chemistry. 259: 3429-3434. PMID 6423631  0.542
1984 Ciudad C, DePaoli-Roach A, Roach PJ. Phosphorylation of glycogen synthase in isolated rabbit hepatocytes Bba - Molecular Cell Research. 804: 261-263. PMID 6326853 DOI: 10.1016/0167-4889(84)90158-7  0.625
1984 Ahmad Z, Camici M, DePaoli-Roach AA, Roach PJ. Glycogen synthase kinases. Classification of a rabbit liver casein and glycogen synthase kinase (casein kinase-1) as a distinct enzyme Journal of Biological Chemistry. 259: 3420-3428. PMID 6323424  0.617
1984 DePaoli-Roach AA. Synergistic phosphorylation and activation of ATP-Mg-dependent phosphoprotein phosphatase by F(A)/GSK-3 and casein kinase II (PC0.7) Journal of Biological Chemistry. 259: 12144-12152. PMID 6090457  0.33
1984 DePaoli-Roach AA. Potentiation by casein kinase II (PC0.7) of the phosphorylation and activation of the ATP-Mg dependent protein phosphatase Federation Proceedings. 43.  0.307
1984 Ahmed Z, Lee FT, DePaoli-Roach AA, Roach PJ. Phosphorylation of glycogen synthase by the Ca2+ and phospholipid dependent protein kinase (protein kinase C) Federation Proceedings. 43.  0.554
1983 DePaoli-Roach AA, Ahmad Z, Camici M, Lawrence JC, Roach PJ. Multiple phosphorylation of rabbit skeletal muscle glycogen synthase. Evidence for interactions among phosphorylation sites and the resolution of electrophoretically distinct forms of the subunit Journal of Biological Chemistry. 258: 10702-10709. PMID 6309812  0.598
1982 Camici M, DePaoli-Roach AA, Roach PJ. Rabbit liver glycogen synthase. Susceptibility of the enzyme subunit to proteolysis Journal of Biological Chemistry. 257: 9898-9901. PMID 6809751  0.558
1982 DePaoli-Roach AA, Roach PJ. Heparin inhibition and polyamine stimulation of a glycogen synthase kinase (PC0.7) from rabbit skeletal muscle Archives of Biochemistry and Biophysics. 217: 305-311. PMID 6289752 DOI: 10.1016/0003-9861(82)90506-9  0.611
1982 Ahmad Z, DePaoli-Roach AA, Roach PJ. Purification and characterization of a rabbit liver calmodulin-dependent protein kinase able to phosphorylate glycogen synthase Journal of Biological Chemistry. 257: 8348-8355. PMID 6282881  0.577
1982 Ahmad Z, DePaoli-Roach AA, Roach PJ. Rabbit liver glycogen synthase kinases. Characterization of a protein kinase (PC0.7) able to phosphorylate glycogen synthase and phosvitin Journal of Biological Chemistry. 257: 5873-5876. PMID 6279617  0.613
1982 DePaoli-Roach AA, Roach PJ. Heparin inhibition and polyamine stimulation of a rabbit muscle glycogen synthese kinase (PC0.7) Federation Proceedings. 41.  0.543
1982 Ahmad Z, DePaoli-Roach AA, Roach PJ. Calmodulin-stimulated glycogen synthase kinase from rabbit liver Federation Proceedings. 41.  0.528
1981 Depaoli-Roach AA, Bingham EW, Roach PJ. Phosphorylase kinase from rabbit skeletal muscle: Phosphorylation of κ-casein Archives of Biochemistry and Biophysics. 212: 229-236. PMID 7305404 DOI: 10.1016/0003-9861(81)90362-3  0.629
1981 DePaoli-Roach AA, Ahmad Z, Roach PJ. Characterization of a rabbit skeletal muscle protein kinase (PC0.7) able to phosphorylate glycogen synthase and phosvitin Journal of Biological Chemistry. 256: 8955-8962. PMID 6790548  0.623
1981 DePaoli-Roach AA, Roach PJ, Pham K, Kramer G, Hardesty B. Phosphorylation of glycogen synthase and of the β subunit of eukaryotic initiation factor two by a common protein kinase Journal of Biological Chemistry. 256: 8871-8874. PMID 6790546  0.587
1979 Depaoli-Roach AA, Gibbs JB, Roach PJ. Calcium and calmodulin activation of muscle phosphorylase kinase. Effect of tryptic proteolysis Febs Letters. 105: 321-324. PMID 488359 DOI: 10.1016/0014-5793(79)80639-0  0.533
1979 Larner J, Galasko G, Cheng K, DePaoli-Roach AA, Huang L, Daggy P, Kellogg J. Generation by insulin of a chemical mediator that controls protein phosphorylation and dephosphorylation Science. 206: 1408-1410. PMID 228395 DOI: 10.1126/Science.228395  0.603
1979 DePaoli-Roach AA, Roach PJ, Larner J. Multiple phosphorylation of rabbit skeletal muscle glycogen synthase. Comparison of the actions of different protein kinases capable of catalyzing phosphorylation in vitro Journal of Biological Chemistry. 254: 12062-12068. PMID 115877  0.602
1979 DePaoli-Roach AA, Roach PJ, Larner J. Rabbit skeletal muscle phosphorylase kinase. Comparison of glycogen synthase and phosphorylase as substrates Journal of Biological Chemistry. 254: 4212-4219. PMID 108271  0.575
1978 Roach PJ, DePaoli-Roach AA, Larner J. Ca2+-stimulated phosphorylation of muscle glycogen synthase by phosphorylase b kinase Journal of Cyclic Nucleotide Research. 4: 245-257. PMID 102668  0.544
1978 DePaoli-Roach AA, Villar-Palasi C, Bergamini E. Effect of denervation on muscle glycogen synthase kinase activity Experimental Neurology. 62: 494-496. PMID 32065 DOI: 10.1016/0014-4886(78)90072-9  0.323
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