| Year |
Citation |
Score |
| 2023 |
Plaza-G A I, Lemishko KM, Crespo R, Truong TQ, Kaguni LS, Cao-García FJ, Ciesielski GL, Ibarra B. Mechanism of strand displacement DNA synthesis by the coordinated activities of human mitochondrial DNA polymerase and SSB. Nucleic Acids Research. 51: 1750-1765. PMID 36744436 DOI: 10.1093/nar/gkad037 |
0.488 |
|
| 2021 |
So M, Stiban J, Ciesielski GL, Hovde SL, Kaguni LS. Implications of Membrane Binding by the Fe-S Cluster-Containing N-Terminal Domain in the Mitochondrial Replicative DNA Helicase. Frontiers in Genetics. 12: 790521. PMID 34950192 DOI: 10.3389/fgene.2021.790521 |
0.461 |
|
| 2021 |
Ciesielski GL, Kim S, de Bovi Pontes C, Kaguni LS. Physical and Functional Interaction of Mitochondrial Single-Stranded DNA-Binding Protein and the Catalytic Subunit of DNA Polymerase Gamma. Frontiers in Genetics. 12: 721864. PMID 34539752 DOI: 10.3389/fgene.2021.721864 |
0.609 |
|
| 2020 |
González de Cózar JM, Carretero-Junquera M, Ciesielski GL, Miettinen SM, Varjosalo M, Kaguni LS, Dufour E, Jacobs HT. A second hybrid-binding domain modulates the activity of Drosophila ribonuclease H1. Journal of Biochemistry. PMID 32589740 DOI: 10.1093/Jb/Mvaa067 |
0.504 |
|
| 2019 |
Salminen TS, Cannino G, Oliveira MT, Lillsunde P, Jacobs HT, Kaguni LS. Lethal Interaction of Nuclear and Mitochondrial Genotypes in Drosophila melanogaster. G3 (Bethesda, Md.). 9: 2225-2234. PMID 33877349 DOI: 10.1534/g3.119.400315 |
0.727 |
|
| 2019 |
Khodour Y, Kaguni LS, Stiban J. Iron-sulfur clusters in nucleic acid metabolism: Varying roles of ancient cofactors. The Enzymes. 45: 225-256. PMID 31627878 DOI: 10.1016/Bs.Enz.2019.08.003 |
0.316 |
|
| 2019 |
Salminen TS, Cannino G, Oliveira MT, Lillsunde P, Jacobs HT, Kaguni LS. Lethal Interaction of Nuclear and Mitochondrial Genotypes in . G3 (Bethesda, Md.). PMID 31076384 DOI: 10.1534/G3.119.400315 |
0.744 |
|
| 2019 |
Cerrón F, de Lorenzo S, Lemishko KM, Ciesielski GL, Kaguni LS, Cao FJ, Ibarra B. Replicative DNA polymerases promote active displacement of SSB proteins during lagging strand synthesis. Nucleic Acids Research. PMID 30968132 DOI: 10.1093/Nar/Gkz249 |
0.544 |
|
| 2019 |
Picchioni D, Antolin-Fontes A, Camacho N, Schmitz C, Pons-Pons A, Rodríguez-Escribà M, Machallekidou A, Güler MN, Siatra P, Carretero-Junquera M, Serrano A, Hovde SL, Knobel PA, Novoa EM, Solà-Vilarrubias M, ... Kaguni LS, et al. Mitochondrial Protein Synthesis and mtDNA Levels Coordinated through an Aminoacyl-tRNA Synthetase Subunit. Cell Reports. 27: 40-47.e5. PMID 30943413 DOI: 10.1016/J.Celrep.2019.03.022 |
0.629 |
|
| 2019 |
Cerron F, Ciesielski GL, Kaguni LS, Cao FJ, Ibarra B. Mechanism of SSB Displacement by Replicative DNA Polymerases During Lagging Strand Synthesis Biophysical Journal. 116: 74a. DOI: 10.1016/J.Bpj.2018.11.443 |
0.463 |
|
| 2018 |
Ciesielski GL, Nadalutti CA, Oliveira MT, Jacobs HT, Griffith JD, Kaguni LS. Structural rearrangements in the mitochondrial genome of Drosophila melanogaster induced by elevated levels of the replicative DNA helicase. Nucleic Acids Research. PMID 29432582 DOI: 10.1093/Nar/Gky094 |
0.763 |
|
| 2018 |
Cerron F, Morin J, Jarillo J, Beltrán-Heredia E, Ciesielski G, Cao F, Kaguni LS, Ibarra B. DNA Synthesis Determines the Binding Mode of the Human Mitochondrial SSB Protein Biophysical Journal. 114: 81a. DOI: 10.1016/J.Bpj.2017.11.490 |
0.573 |
|
| 2017 |
Matsushima Y, Hirofuji Y, Aihara M, Yue S, Uchiumi T, Kaguni LS, Kang D. Drosophila protease ClpXP specifically degrades DmLRPPRC1 controlling mitochondrial mRNA and translation. Scientific Reports. 7: 8315. PMID 28814717 DOI: 10.1038/S41598-017-08088-6 |
0.568 |
|
| 2017 |
Morin JA, Cerrón F, Jarillo J, Beltran-Heredia E, Ciesielski GL, Arias-Gonzalez JR, Kaguni LS, Cao FJ, Ibarra B. DNA synthesis determines the binding mode of the human mitochondrial single-stranded DNA-binding protein. Nucleic Acids Research. PMID 28486639 DOI: 10.1093/Nar/Gkx395 |
0.518 |
|
| 2017 |
Nurminen A, Farnum GA, Kaguni LS. Pathogenicity in POLG syndromes: DNA polymerase gamma pathogenicity prediction server and database. Bba Clinical. 7: 147-156. PMID 28480171 DOI: 10.1016/J.Bbacli.2017.04.001 |
0.517 |
|
| 2017 |
Salminen TS, Oliveira MT, Cannino G, Lillsunde P, Jacobs HT, Kaguni LS. Mitochondrial genotype modulates mtDNA copy number and organismal phenotype in Drosophila. Mitochondrion. PMID 28214560 DOI: 10.1016/J.Mito.2017.02.001 |
0.721 |
|
| 2016 |
Stiban J, So M, Kaguni LS. Iron-Sulfur Clusters in Mitochondrial Metabolism: Multifaceted Roles of a Simple Cofactor. Biochemistry. Biokhimiia. 81: 1066-1080. PMID 27908232 DOI: 10.1134/S0006297916100059 |
0.422 |
|
| 2016 |
Kaguni LS, Oliveira MT, Tamanoi F. Preface. The Enzymes. 39: xi. PMID 27241935 DOI: 10.1016/S1874-6047(16)30017-8 |
0.494 |
|
| 2016 |
Ciesielski GL, Oliveira MT, Kaguni LS. Animal Mitochondrial DNA Replication. The Enzymes. 39: 255-92. PMID 27241933 DOI: 10.1016/bs.enz.2016.03.006 |
0.761 |
|
| 2016 |
Ciesielski GL, Hytönen VP, Kaguni LS. Biolayer Interferometry: A Novel Method to Elucidate Protein-Protein and Protein-DNA Interactions in the Mitochondrial DNA Replisome. Methods in Molecular Biology (Clifton, N.J.). 1351: 223-31. PMID 26530686 DOI: 10.1007/978-1-4939-3040-1_17 |
0.646 |
|
| 2016 |
Ciesielski GL, Rosado-Ruiz FA, Kaguni LS. Purification and Comparative Assay of Human Mitochondrial Single-Stranded DNA-Binding Protein. Methods in Molecular Biology (Clifton, N.J.). 1351: 211-22. PMID 26530685 DOI: 10.1007/978-1-4939-3040-1_16 |
0.637 |
|
| 2016 |
Gajewski JP, Arnold JJ, Salminen TS, Kaguni LS, Cameron CE. Expression and Purification of Mitochondrial RNA Polymerase and Transcription Factor A from Drosophila melanogaster. Methods in Molecular Biology (Clifton, N.J.). 1351: 199-210. PMID 26530684 DOI: 10.1007/978-1-4939-3040-1_15 |
0.53 |
|
| 2016 |
Rosado-Ruiz FA, So M, Kaguni LS. Purification and Comparative Assay of the Human Mitochondrial Replicative DNA Helicase. Methods in Molecular Biology (Clifton, N.J.). 1351: 185-98. PMID 26530683 DOI: 10.1007/978-1-4939-3040-1_14 |
0.663 |
|
| 2016 |
Stiban J, So M, Kaguni LS. Iron-sulfur clusters in mitochondrial metabolism: Multifaceted roles of a simple cofactor Biochemistry (Moscow). 81: 1066-1080. DOI: 10.1134/S0006297916100059 |
0.314 |
|
| 2015 |
Kaguni LS, Oliveira MT. Structure, function and evolution of the animal mitochondrial replicative DNA helicase. Critical Reviews in Biochemistry and Molecular Biology. 1-12. PMID 26615986 DOI: 10.3109/10409238.2015.1117056 |
0.771 |
|
| 2015 |
Ciesielski GL, Bermek O, Rosado-Ruiz FA, Hovde SL, Neitzke OJ, Griffith JD, Kaguni LS. Mitochondrial Single-stranded DNA-binding Proteins Stimulate the Activity of DNA Polymerase γ by Organization of the Template DNA. The Journal of Biological Chemistry. PMID 26446790 DOI: 10.1074/Jbc.M115.673707 |
0.602 |
|
| 2015 |
Oliveira MT, Haukka J, Kaguni LS. Evolution of the metazoan mitochondrial replicase. Genome Biology and Evolution. 7: 943-59. PMID 25740821 DOI: 10.1093/Gbe/Evv042 |
0.74 |
|
| 2014 |
Zabalza R, Nurminen A, Kaguni LS, Garesse R, Gallardo ME, Bornstein B. Co-occurrence of four nucleotide changes associated with an adult mitochondrial ataxia phenotype. Bmc Research Notes. 7: 883. PMID 25488682 DOI: 10.1186/1756-0500-7-883 |
0.624 |
|
| 2014 |
Baqri RM, Pietron AV, Gokhale RH, Turner BA, Kaguni LS, Shingleton AW, Kunes S, Miller KE. Mitochondrial chaperone TRAP1 activates the mitochondrial UPR and extends healthspan in Drosophila. Mechanisms of Ageing and Development. 141: 35-45. PMID 25265088 DOI: 10.1016/J.Mad.2014.09.002 |
0.461 |
|
| 2014 |
Stiban J, Farnum GA, Hovde SL, Kaguni LS. The N-terminal domain of the Drosophila mitochondrial replicative DNA helicase contains an iron-sulfur cluster and binds DNA. The Journal of Biological Chemistry. 289: 24032-42. PMID 25023283 DOI: 10.1074/Jbc.M114.587774 |
0.485 |
|
| 2014 |
Farnum GA, Nurminen A, Kaguni LS. Mapping 136 pathogenic mutations into functional modules in human DNA polymerase γ establishes predictive genotype-phenotype correlations for the complete spectrum of POLG syndromes. Biochimica Et Biophysica Acta. 1837: 1113-21. PMID 24508722 DOI: 10.1016/J.Bbabio.2014.01.021 |
0.405 |
|
| 2014 |
Kaguni LS, Farnum GA, Nurminen A. Predictive clustering of POLG disease mutations into functional modules in the human mitochondrial replicase Biochimica Et Biophysica Acta (Bba) - Bioenergetics. 1837: e58. DOI: 10.1016/J.Bbabio.2014.05.227 |
0.44 |
|
| 2013 |
Fernández-Moreno MA, Hernández R, Adán C, Roberti M, Bruni F, Polosa PL, Cantatore P, Matsushima Y, Kaguni LS, Garesse R. Drosophila nuclear factor DREF regulates the expression of the mitochondrial DNA helicase and mitochondrial transcription factor B2 but not the mitochondrial translation factor B1 Biochimica Et Biophysica Acta - Gene Regulatory Mechanisms. 1829: 1136-1146. PMID 23916463 DOI: 10.1016/J.Bbagrm.2013.07.006 |
0.529 |
|
| 2013 |
Martínez-Azorín F, Calleja M, Hernández-Sierra R, Farr CL, Kaguni LS, Garesse R. Muscle-specific overexpression of the catalytic subunit of DNA polymerase γ induces pupal lethality in Drosophila melanogaster. Archives of Insect Biochemistry and Physiology. 83: 127-37. PMID 23729397 DOI: 10.1002/Arch.21101 |
0.48 |
|
| 2012 |
Sanchez-Martinez A, Calleja M, Peralta S, Matsushima Y, Hernandez-Sierra R, Whitworth AJ, Kaguni LS, Garesse R. Modeling pathogenic mutations of human twinkle in Drosophila suggests an apoptosis role in response to mitochondrial defects. Plos One. 7: e43954. PMID 22952820 DOI: 10.1371/Journal.Pone.0043954 |
0.551 |
|
| 2012 |
Chen S, Oliveira MT, Sanz A, Kemppainen E, Fukuoh A, Schlicht B, Kaguni LS, Jacobs HT. A cytoplasmic suppressor of a nuclear mutation affecting mitochondrial functions in Drosophila. Genetics. 192: 483-93. PMID 22851652 DOI: 10.1534/Genetics.112.143719 |
0.749 |
|
| 2012 |
Peralta S, Clemente P, Sánchez-Martínez A, Calleja M, Hernández-Sierra R, Matsushima Y, Adán C, Ugalde C, Fernández-Moreno MÁ, Kaguni LS, Garesse R. Coiled coil domain-containing protein 56 (CCDC56) is a novel mitochondrial protein essential for cytochrome c oxidase function. The Journal of Biological Chemistry. 287: 24174-85. PMID 22610097 DOI: 10.1074/Jbc.M112.343764 |
0.446 |
|
| 2012 |
Matsushima Y, Kaguni LS. Matrix proteases in mitochondrial DNA function. Biochimica Et Biophysica Acta. 1819: 1080-7. PMID 22172992 DOI: 10.1016/J.Bbagrm.2011.11.008 |
0.628 |
|
| 2011 |
Oliveira MT, Kaguni LS. Reduced stimulation of recombinant DNA polymerase γ and mitochondrial DNA (mtDNA) helicase by variants of mitochondrial single-stranded DNA-binding protein (mtSSB) correlates with defects in mtDNA replication in animal cells. The Journal of Biological Chemistry. 286: 40649-58. PMID 21953457 DOI: 10.1074/Jbc.M111.289983 |
0.79 |
|
| 2011 |
Euro L, Farnum GA, Palin E, Suomalainen A, Kaguni LS. Clustering of Alpers disease mutations and catalytic defects in biochemical variants reveal new features of molecular mechanism of the human mitochondrial replicase, Pol γ. Nucleic Acids Research. 39: 9072-84. PMID 21824913 DOI: 10.1093/Nar/Gkr618 |
0.51 |
|
| 2010 |
Oliveira MT, Kaguni LS. Functional roles of the N- and C-terminal regions of the human mitochondrial single-stranded DNA-binding protein. Plos One. 5: e15379. PMID 21060847 DOI: 10.1371/Journal.Pone.0015379 |
0.779 |
|
| 2010 |
Matsushima Y, Goto Y, Kaguni LS. Mitochondrial Lon protease regulates mitochondrial DNA copy number and transcription by selective degradation of mitochondrial transcription factor A (TFAM). Proceedings of the National Academy of Sciences of the United States of America. 107: 18410-5. PMID 20930118 DOI: 10.1073/Pnas.1008924107 |
0.572 |
|
| 2010 |
Makowska-Grzyska MM, Ziebarth TD, Kaguni LS. Physical analysis of recombinant forms of the human mitochondrial DNA helicase. Methods (San Diego, Calif.). 51: 411-5. PMID 20347039 DOI: 10.1016/J.Ymeth.2010.03.005 |
0.611 |
|
| 2010 |
Ziebarth TD, Gonzalez-Soltero R, Makowska-Grzyska MM, Núñez-Ramírez R, Carazo JM, Kaguni LS. Dynamic effects of cofactors and DNA on the oligomeric state of human mitochondrial DNA helicase. The Journal of Biological Chemistry. 285: 14639-47. PMID 20212038 DOI: 10.1074/Jbc.M109.099663 |
0.636 |
|
| 2010 |
Dallmann HG, Fackelmayer OJ, Tomer G, Chen J, Wiktor-Becker A, Ferrara T, Pope C, Oliveira MT, Burgers PM, Kaguni LS, McHenry CS. Parallel multiplicative target screening against divergent bacterial replicases: identification of specific inhibitors with broad spectrum potential. Biochemistry. 49: 2551-62. PMID 20184361 DOI: 10.1021/Bi9020764 |
0.588 |
|
| 2010 |
Palin EJ, Lesonen A, Farr CL, Euro L, Suomalainen A, Kaguni LS. Functional analysis of H. sapiens DNA polymerase gamma spacer mutation W748S with and without common variant E1143G. Biochimica Et Biophysica Acta. 1802: 545-51. PMID 20153822 DOI: 10.1016/J.Bbadis.2010.02.003 |
0.636 |
|
| 2010 |
Oliveira MT, Garesse R, Kaguni LS. Animal models of mitochondrial DNA transactions in disease and ageing. Experimental Gerontology. 45: 489-502. PMID 20123011 DOI: 10.1016/J.Exger.2010.01.019 |
0.759 |
|
| 2009 |
Baqri RM, Turner BA, Rheuben MB, Hammond BD, Kaguni LS, Miller KE. Disruption of mitochondrial DNA replication in Drosophila increases mitochondrial fast axonal transport in vivo. Plos One. 4: e7874. PMID 19924234 DOI: 10.1371/Journal.Pone.0007874 |
0.57 |
|
| 2009 |
Ziebarth TD, Kaguni LS. Purification strategy for recombinant forms of the human mitochondrial DNA helicase. Methods in Molecular Biology (Clifton, N.J.). 554: 121-6. PMID 19513671 DOI: 10.1007/978-1-59745-521-3_8 |
0.59 |
|
| 2009 |
Oliveira MT, Kaguni LS. Comparative purification strategies for Drosophila and human mitochondrial DNA replication proteins: DNA polymerase gamma and mitochondrial single-stranded DNA-binding protein. Methods in Molecular Biology (Clifton, N.J.). 554: 37-58. PMID 19513666 DOI: 10.1007/978-1-59745-521-3_3 |
0.794 |
|
| 2009 |
Matsushima Y, Kaguni LS. Functional importance of the conserved N-terminal domain of the mitochondrial replicative DNA helicase. Biochimica Et Biophysica Acta. 1787: 290-5. PMID 19063859 DOI: 10.1016/J.Bbabio.2008.11.005 |
0.563 |
|
| 2008 |
Matsushima Y, Farr CL, Fan L, Kaguni LS. Physiological and biochemical defects in carboxyl-terminal mutants of mitochondrial DNA helicase. The Journal of Biological Chemistry. 283: 23964-71. PMID 18593709 DOI: 10.1074/Jbc.M803674200 |
0.599 |
|
| 2008 |
Adán C, Matsushima Y, Hernández-Sierra R, Marco-Ferreres R, Fernández-Moreno MA, González-Vioque E, Calleja M, Aragón JJ, Kaguni LS, Garesse R. Mitochondrial transcription factor B2 is essential for metabolic function in Drosophila melanogaster development. The Journal of Biological Chemistry. 283: 12333-42. PMID 18308726 DOI: 10.1074/Jbc.M801342200 |
0.54 |
|
| 2008 |
Martínez-Azorín F, Calleja M, Hernández-Sierra R, Farr CL, Kaguni LS, Garesse R. Over-expression of the catalytic core of mitochondrial DNA (mtDNA) polymerase in the nervous system of Drosophila melanogaster reduces median life span by inducing mtDNA depletion. Journal of Neurochemistry. 105: 165-76. PMID 17999718 DOI: 10.1111/J.1471-4159.2007.05122.X |
0.566 |
|
| 2007 |
Matsushima Y, Adán C, Garesse R, Kaguni LS. Functional analysis by inducible RNA interference in Drosophila melanogaster. Methods in Molecular Biology (Clifton, N.J.). 372: 207-17. PMID 18314728 DOI: 10.1007/978-1-59745-365-3_15 |
0.359 |
|
| 2007 |
Fernández-Moreno MA, Farr CL, Kaguni LS, Garesse R. Drosophila melanogaster as a model system to study mitochondrial biology. Methods in Molecular Biology (Clifton, N.J.). 372: 33-49. PMID 18314716 DOI: 10.1007/978-1-59745-365-3_3 |
0.508 |
|
| 2007 |
Ziebarth TD, Farr CL, Kaguni LS. Modular architecture of the hexameric human mitochondrial DNA helicase. Journal of Molecular Biology. 367: 1382-91. PMID 17324440 DOI: 10.1016/J.Jmb.2007.01.079 |
0.606 |
|
| 2007 |
Matsushima Y, Kaguni LS. Differential phenotypes of active site and human autosomal dominant progressive external ophthalmoplegia mutations in Drosophila mitochondrial DNA helicase expressed in Schneider cells. The Journal of Biological Chemistry. 282: 9436-44. PMID 17272269 DOI: 10.1074/Jbc.M610550200 |
0.576 |
|
| 2006 |
Sánchez-Martínez A, Luo N, Clemente P, Adán C, Hernández-Sierra R, Ochoa P, Fernández-Moreno MA, Kaguni LS, Garesse R. Modeling human mitochondrial diseases in flies. Biochimica Et Biophysica Acta. 1757: 1190-8. PMID 16806050 DOI: 10.1016/J.Bbabio.2006.05.008 |
0.726 |
|
| 2006 |
Fan L, Kim S, Farr CL, Schaefer KT, Randolph KM, Tainer JA, Kaguni LS. A novel processive mechanism for DNA synthesis revealed by structure, modeling and mutagenesis of the accessory subunit of human mitochondrial DNA polymerase. Journal of Molecular Biology. 358: 1229-43. PMID 16574152 DOI: 10.1016/J.Jmb.2006.02.073 |
0.55 |
|
| 2005 |
Garesse R, Kaguni LS. A Drosophila model of mitochondrial DNA replication: proteins, genes and regulation. Iubmb Life. 57: 555-61. PMID 16118113 DOI: 10.1080/15216540500215572 |
0.658 |
|
| 2005 |
Luoma PT, Luo N, Löscher WN, Farr CL, Horvath R, Wanschitz J, Kiechl S, Kaguni LS, Suomalainen A. Functional defects due to spacer-region mutations of human mitochondrial DNA polymerase in a family with an ataxia-myopathy syndrome. Human Molecular Genetics. 14: 1907-20. PMID 15917273 DOI: 10.1093/Hmg/Ddi196 |
0.664 |
|
| 2005 |
Matsushima Y, Adán C, Garesse R, Kaguni LS. Drosophila mitochondrial transcription factor B1 modulates mitochondrial translation but not transcription or DNA copy number in Schneider cells. The Journal of Biological Chemistry. 280: 16815-20. PMID 15749697 DOI: 10.1074/Jbc.M500569200 |
0.567 |
|
| 2005 |
Luo N, Kaguni LS. Mutations in the spacer region of Drosophila mitochondrial DNA polymerase affect DNA binding, processivity, and the balance between Pol and Exo function. The Journal of Biological Chemistry. 280: 2491-7. PMID 15537632 DOI: 10.1074/Jbc.M411447200 |
0.736 |
|
| 2004 |
Kaguni LS. DNA polymerase gamma, the mitochondrial replicase. Annual Review of Biochemistry. 73: 293-320. PMID 15189144 DOI: 10.1146/Annurev.Biochem.72.121801.161455 |
0.666 |
|
| 2004 |
Matsushima Y, Garesse R, Kaguni LS. Drosophila mitochondrial transcription factor B2 regulates mitochondrial DNA copy number and transcription in schneider cells. The Journal of Biological Chemistry. 279: 26900-5. PMID 15060065 DOI: 10.1074/Jbc.M401643200 |
0.578 |
|
| 2004 |
Farr CL, Matsushima Y, Lagina AT, Luo N, Kaguni LS. Physiological and biochemical defects in functional interactions of mitochondrial DNA polymerase and DNA-binding mutants of single-stranded DNA-binding protein. The Journal of Biological Chemistry. 279: 17047-53. PMID 14754882 DOI: 10.1074/Jbc.M400283200 |
0.745 |
|
| 2002 |
Farr CL, Kaguni LS. Purification strategies for Drosophila mtDNA replication proteins in native and recombinant form. Mitochondrial single-stranded DNA-binding protein. Methods in Molecular Biology (Clifton, N.J.). 197: 285-94. PMID 12013803 DOI: 10.1385/1-59259-284-8:285 |
0.6 |
|
| 2002 |
Farr CL, Kaguni LS. Purification strategies for Drosophila mtDNA replication proteins in native and recombinant form. DNA polymerase gamma. Methods in Molecular Biology (Clifton, N.J.). 197: 273-83. PMID 12013802 DOI: 10.1385/1-59259-284-8:273 |
0.532 |
|
| 2002 |
Iyengar B, Luo N, Farr CL, Kaguni LS, Campos AR. The accessory subunit of DNA polymerase gamma is essential for mitochondrial DNA maintenance and development in Drosophila melanogaster. Proceedings of the National Academy of Sciences of the United States of America. 99: 4483-8. PMID 11917141 DOI: 10.1073/Pnas.072664899 |
0.735 |
|
| 2001 |
Ugalde C, Ochoa P, Pérez ML, Fernández-Moreno MA, Calleja M, Alahari A, Kaguni LS, Garesse R. Identification of a proximal promoter region critical for the expression of the beta-F1-ATPase gene during Drosophila melanogaster development. Mitochondrion. 1: 225-36. PMID 16120280 DOI: 10.1016/S1567-7249(01)00019-8 |
0.34 |
|
| 2001 |
Maier D, Farr CL, Poeck B, Alahari A, Vogel M, Fischer S, Kaguni LS, Schneuwly S. Mitochondrial single-stranded DNA-binding protein is required for mitochondrial DNA replication and development in Drosophila melanogaster Molecular Biology of the Cell. 12: 821-830. PMID 11294889 DOI: 10.1091/Mbc.12.4.821 |
0.668 |
|
| 2001 |
Fan L, Kaguni LS. Multiple regions of subunit interaction in Drosophila mitochondrial DNA polymerase: Three functional domains in the accessory subunit Biochemistry. 40: 4780-4791. PMID 11294646 DOI: 10.1021/Bi010102H |
0.498 |
|
| 2000 |
Lefai E, Calleja M, Ruiz De Mena I, Lagina AT, Kaguni LS, Garesse R. Overexpression of the catalytic subunit of DNA polymerase γ results in depletion of mitochondrial DNA in Drosophila melanogaster Molecular and General Genetics. 264: 37-46. PMID 11016831 DOI: 10.1007/S004380000301 |
0.579 |
|
| 2000 |
Lefai E, Fernandez-Moreno MA, Alahari A, Kaguni LS, Garesse R. Differential regulation of the catalytic and accessory subunit genes of Drosophila mitochondrial DNA polymerase Journal of Biological Chemistry. 275: 33123-33133. PMID 10930405 DOI: 10.1074/Jbc.M003024200 |
0.465 |
|
| 2000 |
Lefai E, Fernández-Moreno MA, Kaguni LS, Garesse R. The highly compact structure of the mitochondrial DNA polymerase genomic region of Drosophila melanogaster: Functional and evolutionary implications Insect Molecular Biology. 9: 315-322. PMID 10886416 DOI: 10.1046/J.1365-2583.2000.00191.X |
0.561 |
|
| 2000 |
Ruiz De Mena I, Lefai E, Garesse R, Kaguni LS. Regulation of mitochondrial single-stranded DNA-binding protein gene expression links nuclear and mitochondrial DNA replication in Drosophila Journal of Biological Chemistry. 275: 13628-13636. PMID 10788480 DOI: 10.1074/Jbc.275.18.13628 |
0.527 |
|
| 1999 |
Ruiz De Mena I, Fernández-Moreno MA, Bornstein B, Kaguni LS, Garesse R. Structure and regulated expression of the δ-aminolevulinate synthase gene from Drosophila melanogaster Journal of Biological Chemistry. 274: 37321-37328. PMID 10601299 DOI: 10.1074/Jbc.274.52.37321 |
0.314 |
|
| 1999 |
Wang Y, Kaguni LS. Baculovirus expression reconstitutes Drosophila mitochondrial DNA polymerase Journal of Biological Chemistry. 274: 28972-28977. PMID 10506144 DOI: 10.1074/Jbc.274.41.28972 |
0.65 |
|
| 1999 |
Fan L, Sanschagrin PC, Kaguni LS, Kuhn LA. The accessory subunit of mtDNA polymerase shares structural homology with aminoacyl-tRNA synthetases: implications for a dual role as a primer recognition factor and processivity clamp. Proceedings of the National Academy of Sciences of the United States of America. 96: 9527-32. PMID 10449726 DOI: 10.1073/Pnas.96.17.9527 |
0.459 |
|
| 1999 |
Farr CL, Wang Y, Kaguni LS. Functional interactions of mitochondrial dna polymerase and single- stranded DNA-binding protein. Template-primer DNA binding and initiation and elongation of DNA strand synthesis Journal of Biological Chemistry. 274: 14779-14785. PMID 10329675 DOI: 10.1074/Jbc.274.21.14779 |
0.589 |
|
| 1997 |
Wang Y, Farr CL, Kaguni LS. Accessory subunit of mitochondrial DNA polymerase from Drosophila embryos: Cloning, molecular analysis, and association in the native enzyme Journal of Biological Chemistry. 272: 13640-13646. PMID 9153213 DOI: 10.1074/Jbc.272.21.13640 |
0.503 |
|
| 1996 |
Lewis DL, Farr CL, Wang Y, Lagina AT, Kaguni LS. Catalytic subunit of mitochondrial DNA polymerase from Drosophila embryos. Cloning, bacterial overexpression, and biochemical characterization. The Journal of Biological Chemistry. 271: 23389-94. PMID 8798543 DOI: 10.1074/Jbc.271.38.23389 |
0.542 |
|
| 1995 |
Lewis DL, Farr CL, Kaguni LS. Drosophila melanogaster mitochondrial DNA: completion of the nucleotide sequence and evolutionary comparisons. Insect Molecular Biology. 4: 263-78. PMID 8825764 |
0.391 |
|
| 1995 |
Williams AJ, Kaguni LS. Stimulation of Drosophila mitochondrial DNA polymerase by single-stranded DNA-binding protein Journal of Biological Chemistry. 270: 860-865. PMID 7822323 DOI: 10.1074/Jbc.270.2.860 |
0.578 |
|
| 1995 |
Thömmes P, Farr CL, Marton RF, Kaguni LS, Cotterill S. Mitochondrial single-stranded DNA-binding protein from Drosophila embryos. Physical and biochemical characterization. The Journal of Biological Chemistry. 270: 21137-43. PMID 7673145 DOI: 10.1074/Jbc.270.36.21137 |
0.614 |
|
| 1995 |
Olson MW, Wang Y, Elder RH, Kaguni LS. Subunit structure of mitochondrial DNA polymerase from Drosophila embryos: Physical and immunological studies Journal of Biological Chemistry. 270: 28932-28937. PMID 7499423 DOI: 10.1074/Jbc.270.48.28932 |
0.614 |
|
| 1994 |
Lewis DL, Farr CL, Farquhar AL, Kaguni LS. Sequence, organization, and evolution of the A+T region of Drosophila melanogaster mitochondrial DNA. Molecular Biology and Evolution. 11: 523-38. PMID 8015445 DOI: 10.1093/Oxfordjournals.Molbev.A040132 |
0.514 |
|
| 1993 |
Williams AJ, Wernette CM, Kaguni LS. Processivity of mitochondrial DNA polymerase from Drosophila embryos: Effects of reaction conditions and enzyme purity Journal of Biological Chemistry. 268: 24855-24862. PMID 8227047 |
0.447 |
|
| 1992 |
Olson MW, Kaguni LS. 3′-5′ Exonuclease in Drosophila mitochondrial DNA polymerase: Substrate specificity and functional coordination of nucleotide polymerization and mispair hydrolysis Journal of Biological Chemistry. 267: 23136-23142. PMID 1429661 |
0.467 |
|
| 1989 |
Kaguni LS, Olson MW. Mismatch-specific 3'→5' exonuclease associated with the mitochondrial DNA polymerase from Drosophila embryos Proceedings of the National Academy of Sciences of the United States of America. 86: 6469-6473. PMID 2671990 DOI: 10.1073/Pnas.86.17.6469 |
0.615 |
|
| 1988 |
Kaguni LS, Lehman IR. Eukaryotic DNA polymerase-primase: structure, mechanism and function. Biochimica Et Biophysica Acta. 950: 87-101. PMID 3289619 DOI: 10.1016/0167-4781(88)90001-2 |
0.459 |
|
| 1988 |
Wernette CM, Conway MC, Kaguni LS. Mitochondrial DNA polymerase from Drosophila melanogaster embryos: kinetics, processivity, and fidelity of DNA polymerization Biochemistry. 27: 6046-6054. PMID 3142517 DOI: 10.1021/Bi00416A033 |
0.594 |
|
| 1986 |
Wernette CM, Kaguni LS. A mitochondrial DNA polymerase from embryos of Drosophila melanogaster. Purification, subunit structure, and partial characterization Journal of Biological Chemistry. 261: 14764-14770. PMID 3095323 |
0.478 |
|
| 1984 |
Kaguni LS, DiFrancesco RA, Lehman IR. The DNA polymerase-primase from drosophila melanogaster embryos. Rate and fidelity of polymerization on single-stranded DNA templates. The Journal of Biological Chemistry. 259: 9314-9. PMID 6235226 |
0.411 |
|
| 1983 |
Kaguni LS, Rossignol JM, Conaway RC, Banks GR, Lehman IR. Association of DNA primase with the beta/gamma subunits of DNA polymerase alpha from Drosophila melanogaster embryos. The Journal of Biological Chemistry. 258: 9037-9. PMID 6409898 |
0.333 |
|
| 1983 |
Kaguni LS, Rossignol JM, Conaway RC, Lehman IR. Isolation of an intact DNA polymerase-primase from embryos of Drosophila melanogaster. Proceedings of the National Academy of Sciences of the United States of America. 80: 2221-5. PMID 6403945 |
0.311 |
|
| 1982 |
Kaguni LS, Clayton DA. Template directed pausing in in vitro DNA synthesis by DNA polymerase α from Drosophila melanogaster embryos Proceedings of the National Academy of Sciences of the United States of America. 79: 983-987. PMID 6803240 |
0.373 |
|
| 1981 |
Kaguni LS, Kaguni JM, Ray DS. Replication of M13 oriC bacteriophages in an Escherichia coli rep mutant is dependent on the cloned Escherichia coli replication origin Journal of Bacteriology. 145: 974-979. PMID 6257657 DOI: 10.1128/Jb.145.2.974-979.1981 |
0.326 |
|
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