| Year |
Citation |
Score |
| 2023 |
Ciulla DA, Xu Z, Pezzullo JL, Dranchak P, Wang C, Giner JL, Inglese J, Callahan BP. Paracatalytic induction: Subverting specificity in hedgehog protein autoprocessing with small molecules. Methods in Enzymology. 685: 1-41. PMID 37245899 DOI: 10.1016/bs.mie.2023.03.001 |
0.579 |
|
| 2022 |
Ciulla DA, Dranchak P, Pezzullo JL, Mancusi RA, Psaras AM, Rai G, Giner JL, Inglese J, Callahan BP. A cell-based bioluminescence reporter assay of human Sonic Hedgehog protein autoprocessing to identify inhibitors and activators. The Journal of Biological Chemistry. 102705. PMID 36400200 DOI: 10.1016/j.jbc.2022.102705 |
0.564 |
|
| 2021 |
Wagner AG, Stagnitta RT, Xu Z, Pezzullo JL, Kandel N, Giner JL, Covey DF, Wang C, Callahan BP. Nanomolar, Noncovalent Antagonism of Hedgehog Cholesterolysis: Exception to the "Irreversibility Rule" for Protein Autoprocessing Inhibition. Biochemistry. PMID 34941260 DOI: 10.1021/acs.biochem.1c00697 |
0.556 |
|
| 2020 |
Smith CJ, Wagner AG, Stagnitta RT, Xu Z, Pezzullo JL, Giner JL, Xie J, Covey DF, Wang C, Callahan BP. Subverting Hedgehog Protein Autoprocessing by Chemical Induction of Paracatalysis. Biochemistry. PMID 32013401 DOI: 10.1021/Acs.Biochem.0C00013 |
0.578 |
|
| 2019 |
Ciulla DA, Wagner AG, Liu X, Cooper CL, Jorgensen MT, Wang C, Goyal P, Banavali NK, Pezzullo JL, Giner JL, Callahan BP. Sterol A-ring plasticity in hedgehog protein cholesterolysis supports a primitive substrate selectivity mechanism. Chemical Communications (Cambridge, England). PMID 30672911 DOI: 10.1039/C8Cc09729A |
0.574 |
|
| 2013 |
Faraldos JA, Coates RM, Giner JL. Alternative synthesis of the Colorado potato beetle pheromone. The Journal of Organic Chemistry. 78: 10548-54. PMID 24047429 DOI: 10.1021/Jo4017056 |
0.668 |
|
| 2005 |
Giner JL, Rocchetti S, Neunlist S, Rohmer M, Arigoni D. Detection of 1,2-hydride shifts in the formation of euph-7-ene by the squalene-tetrahymanol cyclase of Tetrahymena pyriformis. Chemical Communications (Cambridge, England). 3089-91. PMID 15959594 DOI: 10.1039/b504300j |
0.518 |
|
| 2003 |
Giner JL, Faraldos JA, Boyer GL. NOVEL STEROLS OF THE TOXIC DINOFLAGELLATE KARENIA BREVIS (DINOPHYCEAE): A DEFENSIVE FUNCTION FOR UNUSUAL MARINE STEROLS?. Journal of Phycology. 39: 315-319. PMID 33066707 DOI: 10.1046/j.1529-8817.2003.01254.x |
0.655 |
|
| 2003 |
Giner JL, Faraldos JA, Boyer GL. Novel sterols of the toxic dinoflagellate Karenia brevis (Dinophyceae): A defensive function for unusual marine sterols? Journal of Phycology. 39: 315-319. DOI: 10.1046/J.1529-8817.2003.01254.X |
0.655 |
|
| 2003 |
Giner JL, Faraldos JA. Facile Orthoester Formation in a Model Compound of the Taxol Oxetane: Are Biologically Active Epoxy Esters, Orthoesters, and Oxetanyl Esters Latent Electrophiles? Helvetica Chimica Acta. 86: 3613-3622. DOI: 10.1002/Hlca.200390306 |
0.661 |
|
| 2002 |
Faraldos JA, Giner JL. Biomimetic synthesis of petuniasterone D via the epoxy ester[bond]ortho ester rearrangement. The Journal of Organic Chemistry. 67: 4659-66. PMID 12098273 DOI: 10.1021/Jo020068S |
0.664 |
|
| 2002 |
Giner JL, Faraldos JA. A biomimetic approach to the synthesis of an antiviral marine steroidal orthoester. The Journal of Organic Chemistry. 67: 2717-20. PMID 11950327 DOI: 10.1021/Jo011111Z |
0.663 |
|
| 2002 |
Giner JL, Arigoni D. Enantiomerically enriched [2-2H]-isopentenyl alcohol from (E)-2-methylbut-2-ene-1,4-diol by an asymmetric retro-ene reaction Chemical Communications. 1388-1389. |
0.512 |
|
| 1999 |
Arigoni D, Giner JL, Sagner S, Wungsintaweekul J, Zenk MH, Kis K, Bacher A, Eisenreich W. Stereochemical course of the reduction step in the formation of 2-C-methylerythritol from the terpene precursor 1-deoxyxylulose in higher plants Chemical Communications. 1127-1128. DOI: 10.1039/A902216C |
0.528 |
|
| 1998 |
Giner JL, Jaun B, Arigoni D. Biosynthesis of isoprenoids in Escherichia coli: The fate of the 3-H and 4-H atoms of 1-deoxy-D-xylulose Chemical Communications. 1857-1858. |
0.496 |
|
| 1995 |
Giner JL, Djerassi C. A reinvestigation of the biosynthesis of lanosterol in Euphorbia lathyris Phytochemistry. 39: 333-335. DOI: 10.1016/0031-9422(95)00075-I |
0.314 |
|
| 1992 |
Giner JL, Djerassi C. Minor and trace sterols in marine invertebrates 65. 23-Epidihydrocalysterol: a new cyclopropane-containing sponge sterol. Steroids. 57: 258-61. PMID 1440695 DOI: 10.1016/0039-128X(92)90057-G |
0.352 |
|
| 1992 |
Giner JL, Djerassi C. Biosynthetic studies of marine lipids. 40. Generation of the cyclopropane ring of sormosterol. Acta Chemica Scandinavica (Copenhagen, Denmark : 1989). 46: 678-9. PMID 1419436 |
0.346 |
|
| 1992 |
Silva CJ, Giner JL, Djerassi C. Biosynthetic studies of marine lipids. 37. Enzymatic desaturation of 24(S)-methylcholesterol to 23,24-methylenecholesterol, norficisterol, and norhebesterol. Further evidence for a unified biosynthesis of marine sterols with unique side chains Journal of the American Chemical Society. 114: 295-299. DOI: 10.1021/Ja00027A037 |
0.331 |
|
| 1992 |
Giner JL, Djerassi C. Evidence for sterol side-chain dealkylation in Chlamydomonas reinhardtii Phytochemistry. 31: 3865-3867. DOI: 10.1016/S0031-9422(00)97543-5 |
0.308 |
|
| 1991 |
Giner JL, Djerassi C. Biosynthetic studies of marine lipids. 33. Biosynthesis of dinosterol, peridinosterol, and gorgosterol: Unusual patterns of bioalkylation in dinoflagellate sterols Journal of Organic Chemistry. 56: 2357-2363. DOI: 10.1021/Jo00007A021 |
0.306 |
|
| 1991 |
Giner JL, Djerassi C. Biosynthetic studies of marine lipids. 31.1 Evidence for a protonated cyclopropyl intermediate in the biosynthesis of 24-propylidenecholesterol Journal of the American Chemical Society. 113: 1386-1393. DOI: 10.1021/Ja00004A047 |
0.325 |
|
| 1990 |
Giner JL, Djerassi C. Inhibition and substrate specificity of yeast delta 22-desaturase. Biochemical and Biophysical Research Communications. 173: 60-6. PMID 2256937 DOI: 10.1016/S0006-291X(05)81021-6 |
0.335 |
|
| 1990 |
Giner JL, Silva CJ, Djerassi C. Biosynthetic studies of marine lipids. 32. The missing step in sterol cyclopropyl biosynthesis: Enzymatic desaturation of 24(S)-ethylcholesterol Journal of the American Chemical Society. 112: 9626-9627. DOI: 10.1021/Ja00182A025 |
0.337 |
|
| 1990 |
Giner JL, Djerassi C. Biosynthetic studies of marine lipids-XXCIII. Use of sponge cell-free extracts in the study of marine sterol biosynthesis Tetrahedron Letters. 31: 5421-5424. DOI: 10.1016/S0040-4039(00)97862-6 |
0.322 |
|
| 1989 |
Giner JL, Margot C, Djerassi C. Scope and regiochemical control of the allylpotassium reaction in the synthesis of sterols with unsaturated side chains Journal of Organic Chemistry. 54: 2117-2125. DOI: 10.1021/Jo00270A021 |
0.315 |
|
| 1988 |
Giner JL, Zimmerman MP, Djerassi C. Synthesis of (24R,28R)- and (24S,28S)-24,28-methylene-5-stigmasten-3β-ol and biosynthetic implications of cyclopropyl cleavage to 24-substituted cholesterols Journal of Organic Chemistry. 53: 5895-5902. DOI: 10.1021/Jo00260A018 |
0.38 |
|
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