Cathie Pfleger - Publications

Affiliations: 
Icahn School of Medicine at Mount Sinai, New York, NY, United States 

25/66 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Washington C, Chernet R, Gokhale RH, Martino-Cortez Y, Liu HY, Rosenberg AM, Shahar S, Pfleger CM. A conserved, N-terminal tyrosine signal directs Ras for inhibition by Rabex-5. Plos Genetics. 16: e1008715. PMID 32559233 DOI: 10.1371/Journal.Pgen.1008715  0.44
2016 Jahanshahi M, Hsiao K, Jenny A, Pfleger CM. The Hippo Pathway Targets Rae1 to Regulate Mitosis and Organ Size and to Feed Back to Regulate Upstream Components Merlin, Hippo, and Warts. Plos Genetics. 12: e1006198. PMID 27494403 DOI: 10.1371/Journal.Pgen.1006198  0.32
2015 Reimels TA, Pfleger CM. Drosophila Rabex-5 restricts Notch activity in hematopoietic cells and maintains hematopoietic homeostasis. Journal of Cell Science. PMID 26567216 DOI: 10.1242/jcs.174433  0.96
2014 Fagan JK, Dollar G, Lu Q, Barnett A, Pechuan Jorge J, Schlosser A, Pfleger C, Adler P, Jenny A. Combover/CG10732, a novel PCP effector for Drosophila wing hair formation. Plos One. 9: e107311. PMID 25207969 DOI: 10.1371/Journal.Pone.0107311  0.96
2013 Ilanges A, Jahanshahi M, Balobin DM, Pfleger CM. Alcohol interacts with genetic alteration of the Hippo tumor suppressor pathway to modulate tissue growth in Drosophila. Plos One. 8: e78880. PMID 24205337 DOI: 10.1371/journal.pone.0078880  0.96
2013 Liu HY, Pfleger CM. Mutation in E1, the ubiquitin activating enzyme, reduces Drosophila lifespan and results in motor impairment. Plos One. 8: e32835. PMID 23382794 DOI: 10.1371/journal.pone.0032835  0.96
2011 Wu K, Yan H, Fang L, Wang X, Pfleger C, Jiang X, Huang L, Pan ZQ. Mono-ubiquitination drives nuclear export of the human DCN1-like protein hDCNL1. The Journal of Biological Chemistry. 286: 34060-70. PMID 21813641 DOI: 10.1074/Jbc.M111.273045  0.96
2011 Pfleger CM. Ubiquitin on ras: warden or partner in crime? Science Signaling. 4: pe12. PMID 21386093 DOI: 10.1126/scisignal.2001874  0.96
2010 Wang J, Pfleger CM, Friedman L, Vittorino R, Zhao W, Qian X, Conley L, Ho L, Pasinetti GM. POTENTIAL APPLICATION OF GRAPE DERIVED POLYPHENOLS IN HUNTINGTON'S DISEASE. Translational Neuroscience. 1: 95-100. PMID 21331299 DOI: 10.2478/V10134-010-0022-Y  0.96
2010 Pfleger CM, Wang J, Friedman L, Vittorino R, Conley LM, Ho L, Fivecoat HC, Pasinetti GM. Grape-seed polyphenolic extract improves the eye phenotype in a Drosophila model of tauopathy. International Journal of Alzheimer's Disease. 2010. PMID 20871666 DOI: 10.4061/2010/576357  0.96
2010 Yan H, Jahanshahi M, Horvath EA, Liu HY, Pfleger CM. Rabex-5 ubiquitin ligase activity restricts Ras signaling to establish pathway homeostasis in Drosophila. Current Biology : Cb. 20: 1378-82. PMID 20655224 DOI: 10.1016/J.Cub.2010.06.058  0.96
2009 Yan H, Chin ML, Horvath EA, Kane EA, Pfleger CM. Impairment of ubiquitylation by mutation in Drosophila E1 promotes both cell-autonomous and non-cell-autonomous Ras-ERK activation in vivo. Journal of Cell Science. 122: 1461-70. PMID 19366732 DOI: 10.1242/Jcs.042267  0.96
2008 Pfleger CM, Reiter LT. Recent efforts to model human diseases in vivo in Drosophila. Fly. 2: 129-32. PMID 18820469 DOI: 10.4161/Fly.6332  0.96
2007 Pfleger CM, Harvey KF, Yan H, Hariharan IK. Mutation of the gene encoding the ubiquitin activating enzyme ubal causes tissue overgrowth in Drosophila. Fly. 1: 95-105. PMID 18820468 DOI: 10.4161/Fly.4285  0.96
2006 Mills K, Daish T, Harvey KF, Pfleger CM, Hariharan IK, Kumar S. The Drosophila melanogaster Apaf-1 homologue ARK is required for most, but not all, programmed cell death. The Journal of Cell Biology. 172: 809-15. PMID 16533943 DOI: 10.1083/jcb.200512126  0.96
2005 Delalle I, Pfleger CM, Buff E, Lueras P, Hariharan IK. Mutations in the Drosophila orthologs of the F-actin capping protein alpha- and beta-subunits cause actin accumulation and subsequent retinal degeneration. Genetics. 171: 1757-65. PMID 16143599 DOI: 10.1534/Genetics.105.049213  0.96
2005 Chuang LC, Zhu XN, Herrera CR, Tseng HM, Pfleger CM, Block K, Yew PR. The C-terminal domain of the Xenopus cyclin-dependent kinase inhibitor, p27Xic1, is both necessary and sufficient for phosphorylation-independent proteolysis. The Journal of Biological Chemistry. 280: 35290-8. PMID 16118210 DOI: 10.1074/jbc.M506430200  0.96
2003 Harvey KF, Pfleger CM, Hariharan IK. The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosis. Cell. 114: 457-67. PMID 12941274 DOI: 10.1016/S0092-8674(03)00557-9  0.96
2003 Chabes AL, Pfleger CM, Kirschner MW, Thelander L. Mouse ribonucleotide reductase R2 protein: a new target for anaphase-promoting complex-Cdh1-mediated proteolysis. Proceedings of the National Academy of Sciences of the United States of America. 100: 3925-9. PMID 12655059 DOI: 10.1073/Pnas.0330774100  0.96
2001 Pfleger CM, Lee E, Kirschner MW. Substrate recognition by the Cdc20 and Cdh1 components of the anaphase-promoting complex. Genes & Development. 15: 2396-407. PMID 11562349 DOI: 10.1101/Gad.918201  0.96
2001 Pfleger CM, Salic A, Lee E, Kirschner MW. Inhibition of Cdh1-APC by the MAD2-related protein MAD2L2: a novel mechanism for regulating Cdh1. Genes & Development. 15: 1759-64. PMID 11459825 DOI: 10.1101/Gad.897901  0.96
2000 Collavin L, Monte M, Verardo R, Pfleger C, Schneider C. Cell-cycle regulation of the p53-inducible gene B99. Febs Letters. 481: 57-62. PMID 10984615 DOI: 10.1016/S0014-5793(00)01969-4  0.96
2000 Pfleger CM, Kirschner MW. The KEN box: an APC recognition signal distinct from the D box targeted by Cdh1. Genes & Development. 14: 655-65. PMID 10733526 DOI: 10.1101/Gad.14.6.655  0.96
1996 Foty RA, Pfleger CM, Forgacs G, Steinberg MS. Surface tensions of embryonic tissues predict their mutual envelopment behavior. Development (Cambridge, England). 122: 1611-20. PMID 8625847  0.96
1994 Foty RA, Forgacs G, Pfleger CM, Steinberg MS. Liquid properties of embryonic tissues: Measurement of interfacial tensions. Physical Review Letters. 72: 2298-2301. PMID 10055839 DOI: 10.1103/Physrevlett.72.2298  0.96
Low-probability matches
2018 Lee YA, Noon LA, Akat KM, Ybanez MD, Lee TF, Berres ML, Fujiwara N, Goossens N, Chou HI, Parvin-Nejad FP, Khambu B, Kramer EGM, Gordon R, Pfleger C, Germain D, et al. Autophagy is a gatekeeper of hepatic differentiation and carcinogenesis by controlling the degradation of Yap. Nature Communications. 9: 4962. PMID 30470740 DOI: 10.1038/S41467-018-07338-Z  0.08
2013 Huang C, Martin S, Pfleger C, Du J, Buckner JH, Bluestone JA, Riley JL, Ziegler SF. Cutting Edge: a novel, human-specific interacting protein couples FOXP3 to a chromatin-remodeling complex that contains KAP1/TRIM28. Journal of Immunology (Baltimore, Md. : 1950). 190: 4470-3. PMID 23543754 DOI: 10.4049/Jimmunol.1203561  0.08
2012 Kaas A, Pfleger C, Kharagjitsingh AV, Schloot NC, Hansen L, Buschard K, Koeleman BP, Roep BO, Mortensen HB, Alizadeh BZ. Association between age, IL-10, IFNγ, stimulated C-peptide and disease progression in children with newly diagnosed Type 1 diabetes. Diabetic Medicine : a Journal of the British Diabetic Association. 29: 734-41. PMID 22150609 DOI: 10.1111/j.1464-5491.2011.03544.x  0.08
2011 Pham MN, Hawa MI, Pfleger C, Roden M, Schernthaner G, Pozzilli P, Buzzetti R, Scherbaum WA, Scherbaum W, Seissler J, Kolb H, Hunter S, Leslie RD, Schloot NC. Pro- and anti-inflammatory cytokines in latent autoimmune diabetes in adults, type 1 and type 2 diabetes patients: Action LADA 4. Diabetologia. 54: 1630-8. PMID 21347621 DOI: 10.1007/s00125-011-2088-6  0.08
2011 Pfleger C, Schloot NC, Brendel MD, Burkart V, Hogenkamp V, Bretzel RG, Jaeger C, Eckhard M. Circulating cytokines are associated with human islet graft function in type 1 diabetes. Clinical Immunology (Orlando, Fla.). 138: 154-61. PMID 21094094 DOI: 10.1016/j.clim.2010.10.008  0.08
2010 Kaas A, Pfleger C, Hansen L, Buschard K, Schloot NC, Roep BO, Mortensen HB. Association of adiponectin, interleukin (IL)-1ra, inducible protein 10, IL-6 and number of islet autoantibodies with progression patterns of type 1 diabetes the first year after diagnosis. Clinical and Experimental Immunology. 161: 444-52. PMID 20529086 DOI: 10.1111/j.1365-2249.2010.04193.x  0.08
2010 Pfleger C, Meierhoff G, Kolb H, Schloot NC. Association of T-cell reactivity with beta-cell function in recent onset type 1 diabetes patients. Journal of Autoimmunity. 34: 127-35. PMID 19744828 DOI: 10.1016/j.jaut.2009.08.004  0.08
2008 Pfleger C, Kaas A, Hansen L, Alizadeh B, Hougaard P, Holl R, Kolb H, Roep BO, Mortensen HB, Schloot NC. Relation of circulating concentrations of chemokine receptor CCR5 ligands to C-peptide, proinsulin and HbA1c and disease progression in type 1 diabetes. Clinical Immunology (Orlando, Fla.). 128: 57-65. PMID 18434252 DOI: 10.1016/j.clim.2008.03.458  0.08
2008 Domberg J, Liu C, Chao L, Papewalis C, Pfleger C, Xu K, Willenberg HS, Hermsen D, Scherbaum WA, Schloot NC, Schott M. Circulating chemokines in patients with autoimmune thyroid diseases. Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et MéTabolisme. 40: 416-21. PMID 18415893 DOI: 10.1055/s-2008-1073151  0.08
2008 Pfleger C, Mortensen HB, Hansen L, Herder C, Roep BO, Hoey H, Aanstoot HJ, Kocova M, Schloot NC. Association of IL-1ra and adiponectin with C-peptide and remission in patients with type 1 diabetes. Diabetes. 57: 929-37. PMID 18299313 DOI: 10.2337/db07-1697  0.08
2008 Pfleger C, Schloot N, ter Veld F. Effect of serum content and diluent selection on assay sensitivity and signal intensity in multiplex bead-based immunoassays. Journal of Immunological Methods. 329: 214-8. PMID 17964594 DOI: 10.1016/j.jim.2007.09.011  0.08
2019 Gokhale R, Pfleger CM. The Power of Drosophila Genetics: The Discovery of the Hippo Pathway. Methods in Molecular Biology (Clifton, N.J.). 1893: 3-26. PMID 30565121 DOI: 10.1007/978-1-4939-8910-2_1  0.04
2001 Essenpreis M, Graser K, Hagen T, Pfleger C, Vornberger K, Wörle G. Umweltverträglichkeit der neuen 7er-baureihe Atz Automobiltechnische Zeitschrift. 103: 144.  0.04
2019 Elkholi R, Abraham-Enachescu I, Trotta AP, Rubio-Patiño C, Mohammed JN, Luna-Vargas MPA, Gelles JD, Kaminetsky JR, Serasinghe MN, Zou C, Ali S, McStay GP, Pfleger CM, Chipuk JE. MDM2 Integrates Cellular Respiration and Apoptotic Signaling through NDUFS1 and the Mitochondrial Network. Molecular Cell. PMID 30879903 DOI: 10.1016/J.Molcel.2019.02.012  0.01
2017 Pfleger CM. The Hippo Pathway: A Master Regulatory Network Important in Development and Dysregulated in Disease. Current Topics in Developmental Biology. 123: 181-228. PMID 28236967 DOI: 10.1016/bs.ctdb.2016.12.001  0.01
2016 Reimels TA, Pfleger CM. Methods to Examine the Lymph Gland and Hemocytes in Drosophila Larvae. Journal of Visualized Experiments : Jove. PMID 27929462 DOI: 10.3791/54544  0.01
2014 Magyari M, Koch-Henriksen N, Pfleger CC, Sørensen PS. Physical and social environment and the risk of multiple sclerosis. Multiple Sclerosis and Related Disorders. 3: 600-6. PMID 26265272 DOI: 10.1016/j.msard.2014.07.002  0.01
2014 Magyari M, Koch-Henriksen N, Pfleger CC, Sørensen PS. Gender and autoimmune comorbidity in multiple sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England). 20: 1244-1251. PMID 24500604 DOI: 10.1177/1352458514521515  0.01
2013 Pfleger C, Gohlke H. Efficient and robust analysis of biomacromolecular flexibility using ensembles of network topologies based on fuzzy noncovalent constraints. Structure (London, England : 1993). 21: 1725-34. PMID 23994009 DOI: 10.1016/j.str.2013.07.012  0.01
2013 Krüger DM, Rathi PC, Pfleger C, Gohlke H. CNA web server: rigidity theory-based thermal unfolding simulations of proteins for linking structure, (thermo-)stability, and function. Nucleic Acids Research. 41: W340-8. PMID 23609541 DOI: 10.1093/nar/gkt292  0.01
2013 Pfleger C, Rathi PC, Klein DL, Radestock S, Gohlke H. Constraint Network Analysis (CNA): a Python software package for efficiently linking biomacromolecular structure, flexibility, (thermo-)stability, and function. Journal of Chemical Information and Modeling. 53: 1007-15. PMID 23517329 DOI: 10.1021/ci400044m  0.01
2013 Magyari M, Koch-Henriksen N, Pfleger CC, Sørensen PS. Reproduction and the risk of multiple sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England). 19: 1604-9. PMID 23508651 DOI: 10.1177/1352458513481397  0.01
2013 Pfleger C, Radestock S, Schmidt E, Gohlke H. Global and local indices for characterizing biomolecular flexibility and rigidity. Journal of Computational Chemistry. 34: 220-33. PMID 23007873 DOI: 10.1002/jcc.23122  0.01
2012 Pfleger C, Ebeling G, Bläsche R, Patton M, Patel HH, Kasper M, Barth K. Detection of caveolin-3/caveolin-1/P2X7R complexes in mice atrial cardiomyocytes in vivo and in vitro. Histochemistry and Cell Biology. 138: 231-41. PMID 22585038 DOI: 10.1007/S00418-012-0961-0  0.01
2012 Metz A, Pfleger C, Kopitz H, Pfeiffer-Marek S, Baringhaus KH, Gohlke H. Hot spots and transient pockets: predicting the determinants of small-molecule binding to a protein-protein interface. Journal of Chemical Information and Modeling. 52: 120-33. PMID 22087639 DOI: 10.1021/ci200322s  0.01
2012 Pfleger CR, Pfleger R, Wishart R, Cooper D. Mountain justice Transforming Places: Lessons From Appalachia. 226-238.  0.01
2011 Craig IR, Pfleger C, Gohlke H, Essex JW, Spiegel K. Pocket-space maps to identify novel binding-site conformations in proteins. Journal of Chemical Information and Modeling. 51: 2666-79. PMID 21910474 DOI: 10.1021/Ci200168B  0.01
2011 Gohlke H, Metz A, Pfleger C, Krüger DM, Kazemi S. Towards targeting protein-protein interfaces with small molecules Journal of Cheminformatics. 3. DOI: 10.1186/1758-2946-3-S1-O21  0.01
2011 Rathi PC, Pfleger C, Fulle S, Klein DL, Gohlke H. Statics of Biomacromolecules Modeling of Molecular Properties. 281-299. DOI: 10.1002/9783527636402.ch18  0.01
2010 Barth K, Pfleger C, Linge A, Sim JA, Surprenant A, Steinbronn N, Strasser RH, Kasper M. Increased P2X7R expression in atrial cardiomyocytes of caveolin-1 deficient mice. Histochemistry and Cell Biology. 134: 31-8. PMID 20563595 DOI: 10.1007/s00418-010-0716-8  0.01
2010 Pfleger CC, Flachs EM, Koch-Henriksen N. Social consequences of multiple sclerosis. Part 2. Divorce and separation: a historical prospective cohort study. Multiple Sclerosis (Houndmills, Basingstoke, England). 16: 878-82. PMID 20483882 DOI: 10.1177/1352458510370978  0.01
2010 Pfleger CC, Flachs EM, Koch-Henriksen N. Social consequences of multiple sclerosis: clinical and demographic predictors - a historical prospective cohort study. European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies. 17: 1346-51. PMID 20402759 DOI: 10.1111/j.1468-1331.2010.03020.x  0.01
2010 Pfleger CC, Flachs EM, Koch-Henriksen N. Social consequences of multiple sclerosis (1): early pension and temporary unemployment--a historical prospective cohort study. Multiple Sclerosis (Houndmills, Basingstoke, England). 16: 121-6. PMID 20007430 DOI: 10.1177/1352458509352196  0.01
2010 Jenny A, Pfleger C, Dollar G. Planar cell polarity and the cytoskeleton: Searching for Rho kinase substrates Developmental Biology. 344: 474-475. DOI: 10.1016/J.Ydbio.2010.05.245  0.01
2010 Wirz B, Spurr P, Pfleger C. Enantioselective synthesis of (1R,2S,4S)-7-oxabicyclo[2.2.1]heptan-2-exo-carboxylic acid Tetrahedron Asymmetry. 21: 159-161. DOI: 10.1016/j.tetasy.2009.12.030  0.01
2009 Pfleger CC, Koch-Henriksen N, Stenager E, Flachs EM, Johansen C. Head injury is not a risk factor for multiple sclerosis: a prospective cohort study. Multiple Sclerosis (Houndmills, Basingstoke, England). 15: 294-8. PMID 19028828 DOI: 10.1177/1352458508099475  0.01
2009 Rumi L, Pfleger C, Spurr P, Klinkhammer U, Bannwarth W. Adaptation of an exothermic and acylazide-involving synthesis sequence to microreactor technology Organic Process Research and Development. 13: 747-750. DOI: 10.1021/Op9000516  0.01
2009 Dollar GL, Pfleger C, Jenny A. PCP signaling: A genome-wide screen for new Rho kinase substrates Developmental Biology. 331: 486. DOI: 10.1016/J.Ydbio.2009.05.374  0.01
2009 Pfleger C. Barrier-free access offered to the Fachbibliotheken | Barrierefreier zugang zu den angeboten der ub bodenkultur Voeb-Mitteilungen. 62: 55-56.  0.01
2001 Pfleger C. Half the Easter egg | Das halbe Osterei! Krankenpflege. Soins Infirmiers. 94: 22-23. PMID 2002158868  0.01
2001 Pfleger C. [Half the Easter egg]. Krankenpflege. Soins Infirmiers. 94: 22-3. PMID 11944438  0.01
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