Lih-Chu Chiou, Ph.D. - Publications

Affiliations: 
Pharmacology National Taiwan University, Taipei, Taipei City, Taiwan 
Area:
Drug, Pain, Migraine, Tourette, Schizophrenia, Alzheimer’s disease, Obesity
Website:
http://www.mc.ntu.edu.tw/department/pharmacology/template/english/faculty/Lih-Chu%20Chiou/ENPAGE01.HTM

36 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Sieghart W, Chiou LC, Ernst M, Fabjan J, M Savić M, Lee MT. 6-Containing GABA Receptors: Functional Roles and Therapeutic Potentials. Pharmacological Reviews. 74: 238-270. PMID 35017178 DOI: 10.1124/pharmrev.121.000293  0.309
2018 Lu GL, Lee MT, Chiou LC. Orexin-mediated restoration of hippocampal synaptic potentiation in mice with established cocaine-conditioned place preference. Addiction Biology. PMID 30276922 DOI: 10.1111/Adb.12672  0.324
2018 Fan PC, Lai TH, Hor CC, Lee MT, Huang P, Sieghart W, Ernst M, Knutson DE, Cook J, Chiou LC. The α6 subunit-containing GABA receptor: A novel drug target for inhibition of trigeminal activation. Neuropharmacology. PMID 30016665 DOI: 10.1016/J.Neuropharm.2018.07.017  0.379
2016 Lu GL, Lee CH, Chiou LC. Orexin A induces bidirectional modulation of synaptic plasticity: Inhibiting long-term potentiation and preventing depotentiation. Neuropharmacology. PMID 26965217 DOI: 10.1016/J.Neuropharm.2016.03.005  0.371
2016 Lee HJ, Chang LY, Ho YC, Teng SF, Hwang LL, Mackie K, Chiou LC. Stress induces analgesia via orexin 1 receptor-initiated endocannabinoid/CB1 signaling in the mouse periaqueductal gray. Neuropharmacology. PMID 26907809 DOI: 10.1016/j.neuropharm.2016.02.018  0.328
2015 Ho YC, Cheng JK, Chiou LC. Impairment of adenylyl cyclase-mediated glutamatergic synaptic plasticity in the periaqueductal grey in a rat model of neuropathic pain. The Journal of Physiology. 593: 2955-73. PMID 25868084 DOI: 10.1113/Jp270384  0.324
2015 Baimel C, Bartlett SE, Chiou LC, Lawrence AJ, Muschamp JW, Patkar O, Tung LW, Borgland SL. Orexin/hypocretin role in reward: implications for opioid and other addictions. British Journal of Pharmacology. 172: 334-48. PMID 24641197 DOI: 10.1111/Bph.12639  0.319
2013 Chiou LC, Hu SS, Ho YC. Targeting the cannabinoid system for pain relief? Acta Anaesthesiologica Taiwanica : Official Journal of the Taiwan Society of Anesthesiologists. 51: 161-70. PMID 24529672 DOI: 10.1016/J.Aat.2013.10.004  0.406
2013 Ho YC, Cheng JK, Chiou LC. Hypofunction of glutamatergic neurotransmission in the periaqueductal gray contributes to nerve-injury-induced neuropathic pain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 7825-36. PMID 23637174 DOI: 10.1523/Jneurosci.5583-12.2013  0.346
2012 Liao YY, Lee CW, Ho IK, Chiou LC. Quantitative study of [Tyr10]nociceptin/orphanin FQ (1-11) at NOP receptors in rat periaqueductal gray and expressed NOP receptors in HEK293 cells. Life Sciences. 90: 306-12. PMID 22213115 DOI: 10.1016/J.Lfs.2011.12.004  0.419
2011 Ho YC, Lee HJ, Tung LW, Liao YY, Fu SY, Teng SF, Liao HT, Mackie K, Chiou LC. Activation of orexin 1 receptors in the periaqueductal gray of male rats leads to antinociception via retrograde endocannabinoid (2-arachidonoylglycerol)-induced disinhibition. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 14600-10. PMID 21994376 DOI: 10.1523/Jneurosci.2671-11.2011  0.439
2011 Lee CW, Yan JY, Chiang YC, Hung TW, Wang HL, Chiou LC, Ho IK. Differential pharmacological actions of methadone and buprenorphine in human embryonic kidney 293 cells coexpressing human μ-opioid and opioid receptor-like 1 receptors. Neurochemical Research. 36: 2008-21. PMID 21671107 DOI: 10.1007/S11064-011-0525-Z  0.352
2011 Liao YY, Jiang F, Chiou LC. Quantitative study of the antagonistic effect of (-)-cis-1-Methyl-7-[[4-(2,6-dichlorophenyl)piperidin-1-yl]methyl]-6,7,8,9-tetrahydro-5H-benzocyclohepten-5-ol (SB-612111) on nociceptin/orphanin FQ-mediated potassium channel activation in rat periaqueductal gray slices. European Journal of Pharmacology. 657: 84-8. PMID 21300055 DOI: 10.1016/J.Ejphar.2011.01.057  0.44
2011 Liao HT, Lee HJ, Ho YC, Chiou LC. Capsaicin in the periaqueductal gray induces analgesia via metabotropic glutamate receptor-mediated endocannabinoid retrograde disinhibition. British Journal of Pharmacology. 163: 330-45. PMID 21232043 DOI: 10.1111/j.1476-5381.2011.01214.x  0.367
2011 Liao YY, Teng SF, Lin LC, Kolczewski S, Prinssen EP, Lee LJ, Ho IK, Chiou LC. Functional heterogeneity of nociceptin/orphanin FQ receptors revealed by (+)-5a Compound and Ro 64-6198 in rat periaqueductal grey slices. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 14: 977-89. PMID 21029514 DOI: 10.1017/S146114571000129X  0.546
2010 Chiou LC, Lee HJ, Ho YC, Chen SP, Liao YY, Ma CH, Fan PC, Fuh JL, Wang SJ. Orexins/hypocretins: pain regulation and cellular actions. Current Pharmaceutical Design. 16: 3089-100. PMID 20687883 DOI: 10.2174/138161210793292483  0.41
2010 Hwang LL, Wang CH, Li TL, Chang SD, Lin LC, Chen CP, Chen CT, Liang KC, Ho IK, Yang WS, Chiou LC. Sex differences in high-fat diet-induced obesity, metabolic alterations and learning, and synaptic plasticity deficits in mice. Obesity (Silver Spring, Md.). 18: 463-9. PMID 19730425 DOI: 10.1038/oby.2009.273  0.609
2009 Liao YY, Trapella C, Chiou LC. 1-Benzyl-N-[3-[spiroisobenzofuran-1(3H),4'-piperidin-1-yl]propyl]pyrrolidine-2-carboxamide (Compound 24) antagonizes NOP receptor-mediated potassium channel activation in rat periaqueductal gray slices. European Journal of Pharmacology. 606: 84-9. PMID 19374842 DOI: 10.1016/J.Ejphar.2009.01.036  0.439
2008 Kuo CJ, Liao YY, Guerrini R, Calo' G, Chiou LC. Quantitative study of [(pF)Phe4,Arg14,Lys15]nociceptin/orphanin FQ-NH2 (UFP-102) at NOP receptors in rat periaqueductal gray slices. European Journal of Pharmacology. 579: 110-5. PMID 17976580 DOI: 10.1016/J.Ejphar.2007.10.006  0.448
2007 Li TL, Chiou LC, Lin YS, Hsieh JR, Hwang LL. Electrophysiological study on the effects of leptin in rat dorsal motor nucleus of the vagus. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 292: R2136-43. PMID 17303683 DOI: 10.1152/Ajpregu.00563.2006  0.348
2007 Cheng JK, Lin CS, Chen CC, Yang JR, Chiou LC. Effects of intrathecal injection of T-type calcium channel blockers in the rat formalin test. Behavioural Pharmacology. 18: 1-8. PMID 17218792 DOI: 10.1097/Fbp.0B013E3280141375  0.31
2006 Cheng JK, Chiou LC. Mechanisms of the antinociceptive action of gabapentin. Journal of Pharmacological Sciences. 100: 471-86. PMID 16474201 DOI: 10.1254/Jphs.Cr0050020  0.383
2006 Cheng JK, Chen CC, Yang JR, Chiou LC. The antiallodynic action target of intrathecal gabapentin: Ca2+ channels, KATP channels or N-methyl-d-aspartic acid receptors? Anesthesia and Analgesia. 102: 182-7. PMID 16368827 DOI: 10.1213/01.Ane.0000189550.97536.83  0.376
2005 Chiou LC, Liao YY, Guerrini R, Calo' G. [Nphe1,Arg14,Lys15]N/OFQ-NH2 is a competitive antagonist of NOP receptors in the periaqueductal gray. European Journal of Pharmacology. 515: 47-53. PMID 15896734 DOI: 10.1016/J.Ejphar.2005.03.036  0.418
2004 Chiou LC, Fan SH, Chuang KC, Liao YY, Lee SZ. Pharmacological characterization of nociceptin/orphanin FQ receptors, a novel opioid receptor family, in the midbrain periaqueductal gray. Annals of the New York Academy of Sciences. 1025: 398-403. PMID 15542742 DOI: 10.1196/Annals.1316.049  0.429
2004 Chiou LC, Chuang KC, Wichmann J, Adam G. Ro 64-6198 [(1S,3aS)-8-(2,3,3a,4,5,6-Hexahydro-1H-phenalen-1-yl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one] acts differently from nociceptin/orphanin FQ in rat periaqueductal gray slices. The Journal of Pharmacology and Experimental Therapeutics. 311: 645-51. PMID 15254141 DOI: 10.1124/Jpet.104.070219  0.436
2004 Cheng JK, Lee SZ, Yang JR, Wang CH, Liao YY, Chen CC, Chiou LC. Does gabapentin act as an agonist at native GABA(B) receptors? Journal of Biomedical Science. 11: 346-55. PMID 15067218 DOI: 10.1007/Bf02254439  0.644
2003 Cheng JK, Chou RC, Hwang LL, Chiou LC. Antiallodynic effects of intrathecal orexins in a rat model of postoperative pain. The Journal of Pharmacology and Experimental Therapeutics. 307: 1065-71. PMID 14551290 DOI: 10.1124/jpet.103.056663  0.331
2003 Cheng JK, Lai YJ, Chen CC, Cheng CR, Chiou LC. Magnesium chloride and ruthenium red attenuate the antiallodynic effect of intrathecal gabapentin in a rat model of postoperative pain. Anesthesiology. 98: 1472-9. PMID 12766660 DOI: 10.1097/00000542-200306000-00026  0.305
2002 Chiou LC, Fan SH. CompB (J-113397), selectively and competitively antagonizes nociceptin activation of inwardly rectifying K(+) channels in rat periaqueductal gray slices. Neuropharmacology. 42: 987-92. PMID 12069909 DOI: 10.1016/S0028-3908(02)00051-5  0.443
2002 Chiou LC, Fan SH, Guerrini R, Caló G. [Nphe(1)]N/OFQ-(1-13)-NH(2) is a competitive and selective antagonist at nociceptin/orphanin FQ receptors mediating K(+) channel activation in rat periaqueductal gray slices. Neuropharmacology. 42: 246-52. PMID 11804621 DOI: 10.1016/S0028-3908(01)00159-9  0.438
2000 Young C, Gean PW, Chiou LC, Shen YZ. Docosahexaenoic acid inhibits synaptic transmission and epileptiform activity in the rat hippocampus. Synapse (New York, N.Y.). 37: 90-4. PMID 10881029 DOI: 10.1002/1098-2396(200008)37:2<90::Aid-Syn2>3.0.Co;2-Z  0.366
2000 Chiou LC. Pharmacological characterization of the nociceptin receptor, ORL1. Insight from the inward rectifier activation in the periaqueductal gray. Journal of Biomedical Science. 7: 232-40. PMID 10810242 DOI: 10.1007/Bf02255471  0.415
2000 Chiou L. Pharmacological Characterization of the Nociceptin Receptor, ORL1 Journal of Biomedical Science. 7: 232-240. DOI: 10.1159/000025453  0.373
1999 Chiou LC. [Phe1psi(CH2-NH)Gly2]nociceptin-(1 - 13)-NH2 activation of an inward rectifier as a partial agonist of ORL1 receptors in rat periaqueductal gray. British Journal of Pharmacology. 128: 103-7. PMID 10498840 DOI: 10.1038/Sj.Bjp.0702746  0.327
1999 Chiou LC, Huang LY. Mechanism underlying increased neuronal activity in the rat ventrolateral periaqueductal grey by a mu-opioid. The Journal of Physiology. 518: 551-9. PMID 10381599  0.3
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