Marc Montminy - Publications

Affiliations: 
University of California, San Diego, La Jolla, CA 
Area:
Molecular Biology, Cell Biology, Biochemistry

120 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Morgan HJN, Delfino HBP, Schavinski AZ, Malone SA, Charoy C, Reis NG, Assis AP, Lautherbach N, Silveira WA, Heck LC, Guton D, Domingos AI, Kettelhut IC, Montminy M, Navegantes LCC. Hepatic noradrenergic innervation acts via CREB/CRTC2 to activate gluconeogenesis during cold. Metabolism: Clinical and Experimental. 155940. PMID 38878857 DOI: 10.1016/j.metabol.2024.155940  0.402
2023 Dondi C, Vogler G, Gupta A, Walls SM, Kervadec A, Romero MR, Diop SB, Goode J, Thomas JB, Colas AR, Bodmer R, Montminy M, Ocorr K. The nutrient sensor CRTC & Sarcalumenin / Thinman represent a new pathway in cardiac hypertrophy. Biorxiv : the Preprint Server For Biology. PMID 37873259 DOI: 10.1101/2023.10.02.560407  0.754
2021 Yoon YS, Liu W, Van de Velde S, Matsumura S, Wiater E, Huang L, Montminy M. Activation of the adipocyte CREB/CRTC pathway in obesity. Communications Biology. 4: 1214. PMID 34686752 DOI: 10.1038/s42003-021-02735-5  0.346
2021 Ostojić J, Yoon YS, Sonntag T, Nguyen B, Vaughan JM, Shokhirev M, Montminy M. Transcriptional co-activator regulates melanocyte differentiation and oncogenesis by integrating cAMP and MAPK/ERK pathways. Cell Reports. 35: 109136. PMID 34010639 DOI: 10.1016/j.celrep.2021.109136  0.398
2021 Wang T, Wiater E, Zhang X, Thomas JB, Montminy M. Crtc modulates fasting programs associated with 1-C metabolism and inhibition of insulin signaling. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33723074 DOI: 10.1073/pnas.2024865118  0.484
2020 MADIRAJU AK, Matsumura S, Montminy M. CRTC1 Maintains Metabolic Homeostasis and Protects Against Partial Lipodystrophy & Insulin Resistance by Regulating Diet‐Responsive White Adipose Tissue Remodeling The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.09442  0.38
2019 Sonntag T, Moresco JJ, Yates JR, Montminy M. The KLDpT activation loop motif is critical for MARK kinase activity. Plos One. 14: e0225727. PMID 31794565 DOI: 10.1371/Journal.Pone.0225727  0.417
2019 Rodón L, Svensson RU, Wiater E, Chun MGH, Tsai WW, Eichner LJ, Shaw RJ, Montminy M. The CREB coactivator CRTC2 promotes oncogenesis in LKB1-mutant non-small cell lung cancer. Science Advances. 5: eaaw6455. PMID 31355336 DOI: 10.1126/Sciadv.Aaw6455  0.434
2019 Van de Velde S, Wiater E, Tran M, Hwang Y, Cole PA, Montminy M. CREB promotes beta cell gene expression by targeting Its coactivators to tissue-specific enhancers. Molecular and Cellular Biology. PMID 31182641 DOI: 10.1128/Mcb.00200-19  0.426
2019 Tasoulas J, Rodon L, Kaye FJ, Montminy M, Amelio AL. Adaptive Transcriptional Responses by CRTC Coactivators in Cancer. Trends in Cancer. 5: 111-127. PMID 30755304 DOI: 10.1016/J.Trecan.2018.12.002  0.386
2018 Sonntag T, Ostojić J, Vaughan JM, Moresco JJ, Yoon YS, Yates JR, Montminy M. Mitogenic Signals Stimulate the CREB Coactivator CRTC3 through PP2A Recruitment. Iscience. 11: 134-145. PMID 30611118 DOI: 10.1016/J.Isci.2018.12.012  0.524
2018 Yoon YS, Tsai WW, Van de Velde S, Chen Z, Lee KF, Morgan DA, Rahmouni K, Matsumura S, Wiater E, Song Y, Montminy M. cAMP-inducible coactivator CRTC3 attenuates brown adipose tissue thermogenesis. Proceedings of the National Academy of Sciences of the United States of America. PMID 29784793 DOI: 10.1073/Pnas.1805257115  0.462
2017 Sonntag T, Vaughan JM, Montminy M. 14-3-3 proteins mediate inhibitory effects of cAMP on salt-inducible kinases (SIKs). The Febs Journal. PMID 29211348 DOI: 10.1111/Febs.14351  0.487
2017 Kim JH, Hedrick S, Tsai WW, Wiater E, Le Lay J, Kaestner KH, Leblanc M, Loar A, Montminy M. CREB coactivators CRTC2 and CRTC3 modulate bone marrow hematopoiesis. Proceedings of the National Academy of Sciences of the United States of America. PMID 29078378 DOI: 10.1073/Pnas.1712616114  0.45
2017 Sonntag T, Moresco JJ, Vaughan JM, Matsumura S, Yates JR, Montminy M. Analysis of a cAMP regulated coactivator family reveals an alternative phosphorylation motif for AMPK family members. Plos One. 12: e0173013. PMID 28235073 DOI: 10.1371/Journal.Pone.0173013  0.441
2016 Shen R, Wang B, Giribaldi MG, Ayres J, Thomas JB, Montminy M. Neuronal energy-sensing pathway promotes energy balance by modulating disease tolerance. Proceedings of the National Academy of Sciences of the United States of America. PMID 27208092 DOI: 10.1073/Pnas.1606106113  0.45
2016 Ravnskjaer K, Madiraju A, Montminy M. Role of the cAMP Pathway in Glucose and Lipid Metabolism. Handbook of Experimental Pharmacology. 233: 29-49. PMID 26721678 DOI: 10.1007/164_2015_32  0.493
2015 Luan B, Yoon YS, Le Lay J, Kaestner KH, Hedrick S, Montminy M. CREB pathway links PGE2 signaling with macrophage polarization. Proceedings of the National Academy of Sciences of the United States of America. PMID 26644581 DOI: 10.1073/pnas.1519644112  0.357
2015 Hogan MF, Ravnskjaer K, Matsumura S, Huising MO, Hull RL, Kahn SE, Montminy M. Hepatic Insulin Resistance Following Chronic Activation of the CREB Coactivator CRTC2. The Journal of Biological Chemistry. 290: 25997-6006. PMID 26342077 DOI: 10.1074/Jbc.M115.679266  0.518
2015 Hernandez JB, Chang C, LeBlanc M, Grimm D, Le Lay J, Kaestner KH, Zheng Y, Montminy M. The CREB/CRTC2 pathway modulates autoimmune disease by promoting Th17 differentiation. Nature Communications. 6: 7216. PMID 26031354 DOI: 10.1038/Ncomms8216  0.313
2015 Tsai WW, Matsumura S, Liu W, Phillips NG, Sonntag T, Hao E, Lee S, Hai T, Montminy M. ATF3 mediates inhibitory effects of ethanol on hepatic gluconeogenesis. Proceedings of the National Academy of Sciences of the United States of America. 112: 2699-704. PMID 25730876 DOI: 10.1073/Pnas.1424641112  0.408
2015 Blanchet E, Van de Velde S, Matsumura S, Hao E, LeLay J, Kaestner K, Montminy M. Feedback inhibition of CREB signaling promotes beta cell dysfunction in insulin resistance. Cell Reports. 10: 1149-57. PMID 25704817 DOI: 10.1016/J.Celrep.2015.01.046  0.46
2014 Paz JC, Park S, Phillips N, Matsumura S, Tsai WW, Kasper L, Brindle PK, Zhang G, Zhou MM, Wright PE, Montminy M. Combinatorial regulation of a signal-dependent activator by phosphorylation and acetylation. Proceedings of the National Academy of Sciences of the United States of America. 111: 17116-21. PMID 25404345 DOI: 10.1073/Pnas.1420389111  0.552
2014 Luan B, Goodarzi MO, Phillips NG, Guo X, Chen YD, Yao J, Allison M, Rotter JI, Shaw R, Montminy M. Leptin-mediated increases in catecholamine signaling reduce adipose tissue inflammation via activation of macrophage HDAC4. Cell Metabolism. 19: 1058-65. PMID 24768298 DOI: 10.1016/J.Cmet.2014.03.024  0.496
2013 Ravnskjaer K, Hogan MF, Lackey D, Tora L, Dent SY, Olefsky J, Montminy M. Glucagon regulates gluconeogenesis through KAT2B- and WDR5-mediated epigenetic effects. The Journal of Clinical Investigation. 123: 4318-28. PMID 24051374 DOI: 10.1172/Jci69035  0.53
2013 Tsai WW, Niessen S, Goebel N, Yates JR, Guccione E, Montminy M. PRMT5 modulates the metabolic response to fasting signals. Proceedings of the National Academy of Sciences of the United States of America. 110: 8870-5. PMID 23671120 DOI: 10.1073/Pnas.1304602110  0.577
2013 Yu J, Deng R, Zhu HH, Zhang SS, Zhu C, Montminy M, Davis R, Feng GS. Modulation of fatty acid synthase degradation by concerted action of p38 MAP kinase, E3 ligase COP1, and SH2-tyrosine phosphatase Shp2. The Journal of Biological Chemistry. 288: 3823-30. PMID 23269672 DOI: 10.1074/Jbc.M112.397885  0.448
2012 Luo Q, Viste K, Urday-Zaa JC, Senthil Kumar G, Tsai WW, Talai A, Mayo KE, Montminy M, Radhakrishnan I. Mechanism of CREB recognition and coactivation by the CREB-regulated transcriptional coactivator CRTC2. Proceedings of the National Academy of Sciences of the United States of America. 109: 20865-70. PMID 23213254 DOI: 10.1073/Pnas.1219028109  0.444
2012 Wang Y, Li G, Goode J, Paz JC, Ouyang K, Screaton R, Fischer WH, Chen J, Tabas I, Montminy M. Inositol-1,4,5-trisphosphate receptor regulates hepatic gluconeogenesis in fasting and diabetes. Nature. 485: 128-32. PMID 22495310 DOI: 10.1038/Nature10988  0.794
2011 Van de Velde S, Hogan MF, Montminy M. mTOR links incretin signaling to HIF induction in pancreatic beta cells. Proceedings of the National Academy of Sciences of the United States of America. 108: 16876-82. PMID 21949366 DOI: 10.1073/Pnas.1114228108  0.415
2011 Stewart R, Flechner L, Montminy M, Berdeaux R. CREB is activated by muscle injury and promotes muscle regeneration. Plos One. 6: e24714. PMID 21931825 DOI: 10.1371/Journal.Pone.0024714  0.736
2011 Mihaylova MM, Vasquez DS, Ravnskjaer K, Denechaud PD, Yu RT, Alvarez JG, Downes M, Evans RM, Montminy M, Shaw RJ. Class IIa histone deacetylases are hormone-activated regulators of FOXO and mammalian glucose homeostasis. Cell. 145: 607-21. PMID 21565617 DOI: 10.1016/J.Cell.2011.03.043  0.453
2011 Wang B, Moya N, Niessen S, Hoover H, Mihaylova MM, Shaw RJ, Yates JR, Fischer WH, Thomas JB, Montminy M. A hormone-dependent module regulating energy balance. Cell. 145: 596-606. PMID 21565616 DOI: 10.1016/J.Cell.2011.04.013  0.537
2011 Altarejos JY, Montminy M. CREB and the CRTC co-activators: sensors for hormonal and metabolic signals. Nature Reviews. Molecular Cell Biology. 12: 141-51. PMID 21346730 DOI: 10.1038/Nrm3072  0.541
2011 Mair W, Morantte I, Rodrigues AP, Manning G, Montminy M, Shaw RJ, Dillin A. Lifespan extension induced by AMPK and calcineurin is mediated by CRTC-1 and CREB. Nature. 470: 404-8. PMID 21331044 DOI: 10.1038/Nature09706  0.458
2011 Montminy M, Ferreri K. Cyclic Adenosine Monophosphate Regulation of Gene Transcription Comprehensive Physiology. DOI: 10.1002/Cphy.Cp070113  0.452
2010 Song Y, Altarejos J, Goodarzi MO, Inoue H, Guo X, Berdeaux R, Kim JH, Goode J, Igata M, Paz JC, Hogan MF, Singh PK, Goebel N, Vera L, Miller N, ... ... Montminy M, et al. CRTC3 links catecholamine signalling to energy balance. Nature. 468: 933-9. PMID 21164481 DOI: 10.1038/Nature09564  0.778
2010 Yoon YS, Lee MW, Ryu D, Kim JH, Ma H, Seo WY, Kim YN, Kim SS, Lee CH, Hunter T, Choi CS, Montminy MR, Koo SH. Suppressor of MEK null (SMEK)/protein phosphatase 4 catalytic subunit (PP4C) is a key regulator of hepatic gluconeogenesis. Proceedings of the National Academy of Sciences of the United States of America. 107: 17704-9. PMID 20876121 DOI: 10.1073/Pnas.1012665107  0.461
2010 Zhang EE, Liu Y, Dentin R, Pongsawakul PY, Liu AC, Hirota T, Nusinow DA, Sun X, Landais S, Kodama Y, Brenner DA, Montminy M, Kay SA. Cryptochrome mediates circadian regulation of cAMP signaling and hepatic gluconeogenesis. Nature Medicine. 16: 1152-6. PMID 20852621 DOI: 10.1038/Nm.2214  0.571
2010 Zmuda EJ, Qi L, Zhu MX, Mirmira RG, Montminy MR, Hai T. The roles of ATF3, an adaptive-response gene, in high-fat-diet-induced diabetes and pancreatic beta-cell dysfunction. Molecular Endocrinology (Baltimore, Md.). 24: 1423-33. PMID 20519332 DOI: 10.1210/Me.2009-0463  0.51
2010 Wang Y, Inoue H, Ravnskjaer K, Viste K, Miller N, Liu Y, Hedrick S, Vera L, Montminy M. Targeted disruption of the CREB coactivator Crtc2 increases insulin sensitivity. Proceedings of the National Academy of Sciences of the United States of America. 107: 3087-92. PMID 20133702 DOI: 10.1073/Pnas.0914897107  0.501
2009 Wang Y, Vera L, Fischer WH, Montminy M. The CREB coactivator CRTC2 links hepatic ER stress and fasting gluconeogenesis. Nature. 460: 534-7. PMID 19543265 DOI: 10.1038/Nature08111  0.434
2009 Qi L, Saberi M, Zmuda E, Wang Y, Altarejos J, Zhang X, Dentin R, Hedrick S, Bandyopadhyay G, Hai T, Olefsky J, Montminy M. Adipocyte CREB promotes insulin resistance in obesity. Cell Metabolism. 9: 277-86. PMID 19254572 DOI: 10.1016/J.Cmet.2009.01.006  0.609
2009 Ryu D, Oh KJ, Jo HY, Hedrick S, Kim YN, Hwang YJ, Park TS, Han JS, Choi CS, Montminy M, Koo SH. TORC2 regulates hepatic insulin signaling via a mammalian phosphatidic acid phosphatase, LIPIN1. Cell Metabolism. 9: 240-51. PMID 19254569 DOI: 10.1016/J.Cmet.2009.01.007  0.484
2009 Altarejos J, Goebel N, Conkright M, Inoue H, Xie J, Arias C, Sawchenko P, Montminy M. Reply to: Mouse fertility is not dependent on the CREB coactivator Crtc1 Nature Medicine. 15: 991. DOI: 10.1038/Nm0909-991A  0.325
2008 Liu Y, Dentin R, Chen D, Hedrick S, Ravnskjaer K, Schenk S, Milne J, Meyers DJ, Cole P, Yates J, Olefsky J, Guarente L, Montminy M. A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange. Nature. 456: 269-73. PMID 18849969 DOI: 10.1038/Nature07349  0.536
2008 Altarejos JY, Goebel N, Conkright MD, Inoue H, Xie J, Arias CM, Sawchenko PE, Montminy M. The Creb1 coactivator Crtc1 is required for energy balance and fertility. Nature Medicine. 14: 1112-7. PMID 18758446 DOI: 10.1093/Biolreprod/83.S1.196  0.494
2008 Wang B, Goode J, Best J, Meltzer J, Schilman PE, Chen J, Garza D, Thomas JB, Montminy M. The insulin-regulated CREB coactivator TORC promotes stress resistance in Drosophila. Cell Metabolism. 7: 434-44. PMID 18460334 DOI: 10.1016/J.Cmet.2008.02.010  0.799
2008 Dentin R, Hedrick S, Xie J, Yates J, Montminy M. Hepatic glucose sensing via the CREB coactivator CRTC2. Science (New York, N.Y.). 319: 1402-5. PMID 18323454 DOI: 10.1126/Science.1151363  0.381
2007 Dentin R, Liu Y, Koo SH, Hedrick S, Vargas T, Heredia J, Yates J, Montminy M. Insulin modulates gluconeogenesis by inhibition of the coactivator TORC2. Nature. 449: 366-9. PMID 17805301 DOI: 10.1038/Nature06128  0.817
2007 Ravnskjaer K, Kester H, Liu Y, Zhang X, Lee D, Yates JR, Montminy M. Cooperative interactions between CBP and TORC2 confer selectivity to CREB target gene expression. The Embo Journal. 26: 2880-9. PMID 17476304 DOI: 10.1038/Sj.Emboj.7601715  0.48
2007 Berdeaux R, Goebel N, Banaszynski L, Takemori H, Wandless T, Shelton GD, Montminy M. SIK1 is a class II HDAC kinase that promotes survival of skeletal myocytes. Nature Medicine. 13: 597-603. PMID 17468767 DOI: 10.1038/Nm1573  0.437
2007 Montminy M, Dentin R, Liu Y, Hedrick S. The TORC family of CREB coactivators: Regulators of energy balance The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A45-A  0.302
2006 Koo SH, Montminy M. In vino veritas: a tale of two sirt1s? Cell. 127: 1091-3. PMID 17174885 DOI: 10.1016/J.Cell.2006.11.034  0.336
2006 Qi L, Heredia JE, Altarejos JY, Screaton R, Goebel N, Niessen S, Macleod IX, Liew CW, Kulkarni RN, Bain J, Newgard C, Nelson M, Evans RM, Yates J, Montminy M. TRB3 links the E3 ubiquitin ligase COP1 to lipid metabolism. Science (New York, N.Y.). 312: 1763-6. PMID 16794074 DOI: 10.1126/Science.1123374  0.768
2006 Liu Y, Montminy M. CAT in the HAT: catabolic inhibition by the histone acetyltransferase GCN5. Cell Metabolism. 3: 387-8. PMID 16753572 DOI: 10.1016/J.Cmet.2006.05.006  0.329
2006 Cho CY, Koo SH, Wang Y, Callaway S, Hedrick S, Mak PA, Orth AP, Peters EC, Saez E, Montminy M, Schultz PG, Chanda SK. Identification of the tyrosine phosphatase PTP-MEG2 as an antagonist of hepatic insulin signaling. Cell Metabolism. 3: 367-78. PMID 16679294 DOI: 10.1016/J.Cmet.2006.03.006  0.464
2006 Zhang W, Patil S, Chauhan B, Guo S, Powell DR, Le J, Klotsas A, Matika R, Xiao X, Franks R, Heidenreich KA, Sajan MP, Farese RV, Stolz DB, Tso P, ... ... Montminy M, et al. FoxO1 regulates multiple metabolic pathways in the liver: effects on gluconeogenic, glycolytic, and lipogenic gene expression. The Journal of Biological Chemistry. 281: 10105-17. PMID 16492665 DOI: 10.1074/Jbc.M600272200  0.513
2006 Koo SH, Montminy M. Fatty acids and insulin resistance: a perfect storm. Molecular Cell. 21: 449-50. PMID 16483925 DOI: 10.1016/J.Molcel.2006.02.001  0.381
2005 Shaw RJ, Lamia KA, Vasquez D, Koo SH, Bardeesy N, Depinho RA, Montminy M, Cantley LC. The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin. Science (New York, N.Y.). 310: 1642-6. PMID 16308421 DOI: 10.1126/Science.1120781  0.494
2005 Canettieri G, Koo SH, Berdeaux R, Heredia J, Hedrick S, Zhang X, Montminy M. Dual role of the coactivator TORC2 in modulating hepatic glucose output and insulin signaling. Cell Metabolism. 2: 331-8. PMID 16271533 DOI: 10.1016/J.Cmet.2005.09.008  0.792
2005 Park JM, Greten FR, Wong A, Westrick RJ, Arthur JS, Otsu K, Hoffmann A, Montminy M, Karin M. Signaling pathways and genes that inhibit pathogen-induced macrophage apoptosis--CREB and NF-kappaB as key regulators. Immunity. 23: 319-29. PMID 16169504 DOI: 10.1016/J.Immuni.2005.08.010  0.391
2005 Gardner KH, Montminy M. Can you hear me now? Regulating transcriptional activators by phosphorylation. Science's Stke : Signal Transduction Knowledge Environment. 2005: pe44. PMID 16160121 DOI: 10.1126/Stke.3012005Pe44  0.477
2005 Koo SH, Flechner L, Qi L, Zhang X, Screaton RA, Jeffries S, Hedrick S, Xu W, Boussouar F, Brindle P, Takemori H, Montminy M. The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism. Nature. 437: 1109-11. PMID 16148943 DOI: 10.1038/Nature03967  0.816
2005 Conkright MD, Montminy M. CREB: the unindicted cancer co-conspirator. Trends in Cell Biology. 15: 457-9. PMID 16084096 DOI: 10.1016/J.Tcb.2005.07.007  0.419
2005 Zhang X, Odom DT, Koo SH, Conkright MD, Canettieri G, Best J, Chen H, Jenner R, Herbolsheimer E, Jacobsen E, Kadam S, Ecker JR, Emerson B, Hogenesch JB, Unterman T, ... ... Montminy M, et al. Genome-wide analysis of cAMP-response element binding protein occupancy, phosphorylation, and target gene activation in human tissues. Proceedings of the National Academy of Sciences of the United States of America. 102: 4459-64. PMID 15753290 DOI: 10.1073/Pnas.0501076102  0.521
2005 Mayr BM, Guzman E, Montminy M. Glutamine rich and basic region/leucine zipper (bZIP) domains stabilize cAMP-response element-binding protein (CREB) binding to chromatin. The Journal of Biological Chemistry. 280: 15103-10. PMID 15703171 DOI: 10.1074/Jbc.M414144200  0.422
2004 Montminy M, Koo SH. Diabetes: outfoxing insulin resistance? Nature. 432: 958-9. PMID 15616540 DOI: 10.1038/432958A  0.356
2004 Best JL, Amezcua CA, Mayr B, Flechner L, Murawsky CM, Emerson B, Zor T, Gardner KH, Montminy M. Identification of small-molecule antagonists that inhibit an activator: coactivator interaction. Proceedings of the National Academy of Sciences of the United States of America. 101: 17622-7. PMID 15585582 DOI: 10.1073/Pnas.0406374101  0.763
2004 Screaton RA, Conkright MD, Katoh Y, Best JL, Canettieri G, Jeffries S, Guzman E, Niessen S, Yates JR, Takemori H, Okamoto M, Montminy M. The CREB coactivator TORC2 functions as a calcium- and cAMP-sensitive coincidence detector. Cell. 119: 61-74. PMID 15454081 DOI: 10.1016/J.Cell.2004.09.015  0.487
2004 Kulkarni RN, Jhala US, Winnay JN, Krajewski S, Montminy M, Kahn CR. PDX-1 haploinsufficiency limits the compensatory islet hyperplasia that occurs in response to insulin resistance. The Journal of Clinical Investigation. 114: 828-36. PMID 15372107 DOI: 10.1172/Jci21845  0.366
2004 Montminy M, Koo SH, Zhang X. The CREB Family: Key regulators of hepatic metabolism Annales D'Endocrinologie. 65: 73-75. PMID 15122096 DOI: 10.1016/S0003-4266(04)95634-X  0.314
2004 Koo SH, Satoh H, Herzig S, Lee CH, Hedrick S, Kulkarni R, Evans RM, Olefsky J, Montminy M. PGC-1 promotes insulin resistance in liver through PPAR-alpha-dependent induction of TRB-3. Nature Medicine. 10: 530-4. PMID 15107844 DOI: 10.1038/Nm1044  0.468
2004 Koo S, Satoh H, Herzig S, Lee C, Hedrick S, Kulkarni R, Evans RM, Olefsky J, Montminy M. Erratum: PGC-1 promotes insulin resistance in liver through PPAR-α-dependent induction of TRB-3 Nature Medicine. 10: 755-755. DOI: 10.1038/Nm0704-755A  0.372
2003 Herzig S, Hedrick S, Morantte I, Koo SH, Galimi F, Montminy M. CREB controls hepatic lipid metabolism through nuclear hormone receptor PPAR-gamma. Nature. 426: 190-3. PMID 14614508 DOI: 10.1038/Nature02110  0.506
2003 Conkright MD, Canettieri G, Screaton R, Guzman E, Miraglia L, Hogenesch JB, Montminy M. TORCs: transducers of regulated CREB activity. Molecular Cell. 12: 413-23. PMID 14536081 DOI: 10.1016/J.Molcel.2003.08.013  0.501
2003 Jhala US, Canettieri G, Screaton RA, Kulkarni RN, Krajewski S, Reed J, Walker J, Lin X, White M, Montminy M. cAMP promotes pancreatic beta-cell survival via CREB-mediated induction of IRS2. Genes & Development. 17: 1575-80. PMID 12842910 DOI: 10.1101/Gad.1097103  0.46
2003 Du K, Herzig S, Kulkarni RN, Montminy M. TRB3: a tribbles homolog that inhibits Akt/PKB activation by insulin in liver. Science (New York, N.Y.). 300: 1574-7. PMID 12791994 DOI: 10.1126/Science.1079817  0.477
2003 Conkright MD, Guzmán E, Flechner L, Su AI, Hogenesch JB, Montminy M. Genome-wide analysis of CREB target genes reveals a core promoter requirement for cAMP responsiveness. Molecular Cell. 11: 1101-8. PMID 12718894 DOI: 10.1016/S1097-2765(03)00134-5  0.765
2003 Canettieri G, Morantte I, Guzmán E, Asahara H, Herzig S, Anderson SD, Yates JR, Montminy M. Attenuation of a phosphorylation-dependent activator by an HDAC-PP1 complex. Nature Structural Biology. 10: 175-81. PMID 12567184 DOI: 10.1038/Nsb895  0.463
2003 Montminy M, Du K. Transcriptional Regulation via the cAMP Responsive Activator CREB Handbook of Cell Signaling. 3: 115-118. DOI: 10.1016/B978-012124546-7/50649-5  0.345
2002 Zor T, Mayr BM, Dyson HJ, Montminy MR, Wright PE. Roles of phosphorylation and helix propensity in the binding of the KIX domain of CREB-binding protein by constitutive (c-Myb) and inducible (CREB) activators. The Journal of Biological Chemistry. 277: 42241-8. PMID 12196545 DOI: 10.1074/Jbc.M207361200  0.301
2002 Asahara H, Tartare-Deckert S, Nakagawa T, Ikehara T, Hirose F, Hunter T, Ito T, Montminy M. Dual roles of p300 in chromatin assembly and transcriptional activation in cooperation with nucleosome assembly protein 1 in vitro. Molecular and Cellular Biology. 22: 2974-83. PMID 11940655 DOI: 10.1128/Mcb.22.9.2974-2983.2002  0.321
2001 Xu W, Chen H, Du K, Asahara H, Tini M, Emerson BM, Montminy M, Evans RM. A transcriptional switch mediated by cofactor methylation. Science (New York, N.Y.). 294: 2507-11. PMID 11701890 DOI: 10.1126/Science.1065961  0.406
2001 Asahara H, Santoso B, Guzman E, Du K, Cole PA, Davidson I, Montminy M. Chromatin-dependent cooperativity between constitutive and inducible activation domains in CREB. Molecular and Cellular Biology. 21: 7892-900. PMID 11689682 DOI: 10.1128/Mcb.21.23.7892-7900.2001  0.438
2001 Herzig S, Long F, Jhala US, Hedrick S, Quinn R, Bauer A, Rudolph D, Schutz G, Yoon C, Puigserver P, Spiegelman B, Montminy M. CREB regulates hepatic gluconeogenesis through the coactivator PGC-1. Nature. 413: 179-83. PMID 11557984 DOI: 10.1038/35093131  0.54
2001 Mayr B, Montminy M. Transcriptional regulation by the phosphorylation-dependent factor CREB. Nature Reviews. Molecular Cell Biology. 2: 599-609. PMID 11483993 DOI: 10.1038/35085068  0.473
2001 Dutta S, Gannon M, Peers B, Wright C, Bonner-Weir S, Montminy M. PDX:PBX complexes are required for normal proliferation of pancreatic cells during development Proceedings of the National Academy of Sciences. 98: 1065-1070. DOI: 10.1073/Pnas.98.3.1065  0.369
2001 Herzig S, Long F, Jhala US, Hedrick S, Quinn R, Bauer A, Rudolph D, Schutz G, Yoon C, Puigserver P, Spiegelman B, Montminy M. Erratum: correction: CREB regulates hepatic gluconeogenesis through the coactivator PGC-1 Nature. 413: 652-652. DOI: 10.1038/35098123  0.454
2000 von Mikecz A, Zhang S, Montminy M, Tan EM, Hemmerich P. CREB-binding protein (CBP)/p300 and RNA polymerase II colocalize in transcriptionally active domains in the nucleus. The Journal of Cell Biology. 150: 265-73. PMID 10893273 DOI: 10.1083/Jcb.150.1.265  0.367
2000 Du K, Asahara H, Jhala US, Wagner BL, Montminy M. Characterization of a CREB gain-of-function mutant with constitutive transcriptional activity in vivo. Molecular and Cellular Biology. 20: 4320-7. PMID 10825195 DOI: 10.1128/Mcb.20.12.4320-4327.2000  0.523
2000 Wagner BL, Bauer A, Schütz G, Montminy M. Stimulus-specific interaction between activator-coactivator cognates revealed with a novel complex-specific antiserum. The Journal of Biological Chemistry. 275: 8263-6. PMID 10722651 DOI: 10.1074/Jbc.275.12.8263  0.416
2000 Michael LF, Asahara H, Shulman AI, Kraus WL, Montminy M. The phosphorylation status of a cyclic AMP-responsive activator is modulated via a chromatin-dependent mechanism. Molecular and Cellular Biology. 20: 1596-603. PMID 10669737 DOI: 10.1128/Mcb.20.5.1596-1603.2000  0.491
1999 Asahara H, Dutta S, Kao HY, Evans RM, Montminy M. Pbx-Hox heterodimers recruit coactivator-corepressor complexes in an isoform-specific manner. Molecular and Cellular Biology. 19: 8219-25. PMID 10567547 DOI: 10.1128/Mcb.19.12.8219  0.426
1999 Malecki MT, Jhala US, Antonellis A, Fields L, Doria A, Orban T, Saad M, Warram JH, Montminy M, Krolewski AS. Mutations in NEUROD1 are associated with the development of type 2 diabetes mellitus Nature Genetics. 23: 323-328. PMID 10545951 DOI: 10.1038/15500  0.395
1999 Parker D, Rivera M, Zor T, Henrion-Caude A, Radhakrishnan I, Kumar A, Shapiro LH, Wright PE, Montminy M, Brindle PK. Role of secondary structure in discrimination between constitutive and inducible activators. Molecular and Cellular Biology. 19: 5601-7. PMID 10409749 DOI: 10.1128/Mcb.19.8.5601  0.394
1998 Du K, Montminy M. CREB is a regulatory target for the protein kinase Akt/PKB Journal of Biological Chemistry. 273: 32377-32379. PMID 9829964 DOI: 10.1074/Jbc.273.49.32377  0.494
1998 Parker D, Jhala US, Radhakrishnan I, Yaffe MB, Reyes C, Shulman AI, Cantley LC, Wright PE, Montminy M. Analysis of an activator:coactivator complex reveals an essential role for secondary structure in transcriptional activation. Molecular Cell. 2: 353-9. PMID 9774973 DOI: 10.1016/S1097-2765(00)80279-8  0.478
1998 Blobel GA, Nakajima T, Eckner R, Montminy M, Orkin SH. CREB-binding protein cooperates with transcription factor GATA-1 and is required for erythroid differentiation Proceedings of the National Academy of Sciences of the United States of America. 95: 2061-2066. PMID 9482838 DOI: 10.1073/Pnas.95.5.2061  0.419
1997 Nakajima T, Uchida C, Anderson SF, Chee-Gun L, Hurwitz J, Parvin JD, Montminy M. RNA helicase A mediates association of CBP with RNA polymerase II Cell. 90: 1107-1112. PMID 9323138 DOI: 10.1016/S0092-8674(00)80376-1  0.335
1997 Montminy M. Transcriptional Regulation by Cyclic AMP Annual Review of Biochemistry. 66: 807-822. PMID 9242925 DOI: 10.1146/Annurev.Biochem.66.1.807  0.473
1997 Montminy M. Transcriptional activation. Something new to hang your HAT on. Nature. 387: 654-5. PMID 9192883 DOI: 10.1038/42594  0.371
1997 Sharma S, Jhala US, Johnson T, Ferreri K, Leonard J, Montminy M. Hormonal regulation of an islet-specific enhancer in the pancreatic homeobox gene STF-1. Molecular and Cellular Biology. 17: 2598-2604. PMID 9111329 DOI: 10.1128/Mcb.17.5.2598  0.379
1997 Nakajima T, Uchida C, Anderson SF, Parvin JD, Montminy M. Analysis of a cAMP-responsive activator reveals a two-component mechanism for transcriptional induction via signal-dependent factors. Genes & Development. 11: 738-47. PMID 9087428 DOI: 10.1101/Gad.11.6.738  0.45
1996 Chakravarti D, LaMorte VJ, Nelson MC, Nakajima T, Schulman IG, Juguilon H, Montminy M, Evans RM. Role of CBP/P300 in nuclear receptor signalling. Nature. 383: 99-103. PMID 8779723 DOI: 10.1038/383099A0  0.401
1996 Montminy M, Brindle P, Arias J, Ferreri K, Armstrong R. Regulation of somatostatin gene transcription by cyclic adenosine monophosphate Metabolism: Clinical and Experimental. 45: 4-7. PMID 8769368 DOI: 10.1016/S0026-0495(96)90068-2  0.503
1995 Peers B, Sharma S, Johnson T, Kamps M, Montminy M. The pancreatic islet factor STF-1 binds cooperatively with Pbx to a regulatory element in the somatostatin promoter: importance of the FPWMK motif and of the homeodomain. Molecular and Cellular Biology. 15: 7091-7. PMID 8524276 DOI: 10.1128/Mcb.15.12.7091  0.398
1995 Armstrong R, Wen W, Meinkoth J, Taylor S, Montminy M. A refractory phase in cyclic AMP-responsive transcription requires down regulation of protein kinase A. Molecular and Cellular Biology. 15: 1826-32. PMID 7862172 DOI: 10.1128/Mcb.15.3.1826  0.48
1995 Montminy M, Brindle P, Arias J, Ferreri K, Armstrong R. Regulation of somatostatin gene transcription by cAMP Ciba Foundation Symposium. 190: 7-20; discussion 20. PMID 7587654 DOI: 10.1016/S1054-3589(08)60573-6  0.53
1995 Brindle P, Nakajima T, Montminy M. Multiple protein kinase A-regulated events are required for transcriptional induction by cAMP Proceedings of the National Academy of Sciences of the United States of America. 92: 10521-10525. PMID 7479832 DOI: 10.1073/Pnas.92.23.10521  0.511
1995 Bertherat J, Chanson P, Montminy M. The cyclic adenosine 3',5'-monophosphate-responsive factor CREB is constitutively activated in human somatotroph adenomas. Molecular Endocrinology. 9: 777-783. PMID 7476961 DOI: 10.1210/Mend.9.7.7476961  0.425
1994 Arias J, Alberts AS, Brindle P, Claret FX, Smeal T, Karin M, Feramisco J, Montminy M. Activation of cAMP and mitogen responsive genes relies on a common nuclear factor. Nature. 370: 226-9. PMID 8028671 DOI: 10.1038/370226A0  0.538
1994 Ferreri K, Gill G, Montminy M. The cAMP-regulated transcription factor CREB interacts with a component of the TFIID complex Proceedings of the National Academy of Sciences of the United States of America. 91: 1210-1213. PMID 7906413 DOI: 10.1073/Pnas.91.4.1210  0.452
1994 Alberts AS, Montminy M, Shenolikar S, Feramisco JR. Expression of a peptide inhibitor of protein phosphatase 1 increases phosphorylation and activity of CREB in NIH 3T3 fibroblasts. Molecular and Cellular Biology. 14: 4398-407. PMID 7516466 DOI: 10.1128/Mcb.14.7.4398  0.47
1993 Brindle P, Linke S, Montminy M. Protein-kinase-A-dependent activator in transcription factor CREB reveals new role for CREM repressors Nature. 364: 821-824. PMID 8102791 DOI: 10.1038/364821A0  0.484
1993 Meinkoth JL, Alberts AS, Went W, Fantozzi D, Taylor SS, Hagiwara M, Montminy M, Feramisco JR. Signal transduction through the cAMP-dependent protein kinase. Molecular and Cellular Biochemistry. 127: 179-86. PMID 7935349 DOI: 10.1007/Bf01076769  0.42
1992 Leonard J, Serup P, Gonzalez G, Edlund T, Montminy M. The LIM family transcription factor Isl-1 requires cAMP response element binding protein to promote somatostatin expression in pancreatic islet cells Proceedings of the National Academy of Sciences of the United States of America. 89: 6247-6251. PMID 1352885 DOI: 10.1073/Pnas.89.14.6247  0.504
1992 Hagiwara M, Alberts A, Brindle P, Meinkoth J, Feramisco J, Deng T, Karin M, Shenolikar S, Montminy M. Transcriptional attenuation following cAMP induction requires PP-1-mediated dephosphorylation of CREB. Cell. 70: 105-13. PMID 1352481 DOI: 10.1016/0092-8674(92)90537-M  0.493
1990 Lamph WW, Dwarki VJ, Ofir R, Montminy M, Verma IM. Negative and positive regulation by transcription factor cAMP response element-binding protein is modulated by phosphorylation. Proceedings of the National Academy of Sciences of the United States of America. 87: 4320-4. PMID 2140898 DOI: 10.1073/Pnas.87.11.4320  0.479
1990 Dwarki V, Montminy M, Verma I. Both the basic region and the ‘leucine zipper’ domain of the cyclic AMP response element binding (CREB) protein are essential for transcriptional activation. The Embo Journal. 9: 225-232. DOI: 10.1002/J.1460-2075.1990.Tb08099.X  0.433
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