Year |
Citation |
Score |
2024 |
Morgan HJN, Delfino HBP, Schavinski AZ, Malone SA, Charoy C, Reis NG, Assis AP, Lautherbach N, Silveira WA, Heck LC, Guton D, Domingos AI, Kettelhut IC, Montminy M, Navegantes LCC. Hepatic noradrenergic innervation acts via CREB/CRTC2 to activate gluconeogenesis during cold. Metabolism: Clinical and Experimental. 155940. PMID 38878857 DOI: 10.1016/j.metabol.2024.155940 |
0.402 |
|
2023 |
Dondi C, Vogler G, Gupta A, Walls SM, Kervadec A, Romero MR, Diop SB, Goode J, Thomas JB, Colas AR, Bodmer R, Montminy M, Ocorr K. The nutrient sensor CRTC & Sarcalumenin / Thinman represent a new pathway in cardiac hypertrophy. Biorxiv : the Preprint Server For Biology. PMID 37873259 DOI: 10.1101/2023.10.02.560407 |
0.754 |
|
2021 |
Yoon YS, Liu W, Van de Velde S, Matsumura S, Wiater E, Huang L, Montminy M. Activation of the adipocyte CREB/CRTC pathway in obesity. Communications Biology. 4: 1214. PMID 34686752 DOI: 10.1038/s42003-021-02735-5 |
0.346 |
|
2021 |
Ostojić J, Yoon YS, Sonntag T, Nguyen B, Vaughan JM, Shokhirev M, Montminy M. Transcriptional co-activator regulates melanocyte differentiation and oncogenesis by integrating cAMP and MAPK/ERK pathways. Cell Reports. 35: 109136. PMID 34010639 DOI: 10.1016/j.celrep.2021.109136 |
0.398 |
|
2021 |
Wang T, Wiater E, Zhang X, Thomas JB, Montminy M. Crtc modulates fasting programs associated with 1-C metabolism and inhibition of insulin signaling. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33723074 DOI: 10.1073/pnas.2024865118 |
0.484 |
|
2020 |
MADIRAJU AK, Matsumura S, Montminy M. CRTC1 Maintains Metabolic Homeostasis and Protects Against Partial Lipodystrophy & Insulin Resistance by Regulating Diet‐Responsive White Adipose Tissue Remodeling The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.09442 |
0.38 |
|
2019 |
Sonntag T, Moresco JJ, Yates JR, Montminy M. The KLDpT activation loop motif is critical for MARK kinase activity. Plos One. 14: e0225727. PMID 31794565 DOI: 10.1371/Journal.Pone.0225727 |
0.417 |
|
2019 |
Rodón L, Svensson RU, Wiater E, Chun MGH, Tsai WW, Eichner LJ, Shaw RJ, Montminy M. The CREB coactivator CRTC2 promotes oncogenesis in LKB1-mutant non-small cell lung cancer. Science Advances. 5: eaaw6455. PMID 31355336 DOI: 10.1126/Sciadv.Aaw6455 |
0.434 |
|
2019 |
Van de Velde S, Wiater E, Tran M, Hwang Y, Cole PA, Montminy M. CREB promotes beta cell gene expression by targeting Its coactivators to tissue-specific enhancers. Molecular and Cellular Biology. PMID 31182641 DOI: 10.1128/Mcb.00200-19 |
0.426 |
|
2019 |
Tasoulas J, Rodon L, Kaye FJ, Montminy M, Amelio AL. Adaptive Transcriptional Responses by CRTC Coactivators in Cancer. Trends in Cancer. 5: 111-127. PMID 30755304 DOI: 10.1016/J.Trecan.2018.12.002 |
0.386 |
|
2018 |
Sonntag T, Ostojić J, Vaughan JM, Moresco JJ, Yoon YS, Yates JR, Montminy M. Mitogenic Signals Stimulate the CREB Coactivator CRTC3 through PP2A Recruitment. Iscience. 11: 134-145. PMID 30611118 DOI: 10.1016/J.Isci.2018.12.012 |
0.524 |
|
2018 |
Yoon YS, Tsai WW, Van de Velde S, Chen Z, Lee KF, Morgan DA, Rahmouni K, Matsumura S, Wiater E, Song Y, Montminy M. cAMP-inducible coactivator CRTC3 attenuates brown adipose tissue thermogenesis. Proceedings of the National Academy of Sciences of the United States of America. PMID 29784793 DOI: 10.1073/Pnas.1805257115 |
0.462 |
|
2017 |
Sonntag T, Vaughan JM, Montminy M. 14-3-3 proteins mediate inhibitory effects of cAMP on salt-inducible kinases (SIKs). The Febs Journal. PMID 29211348 DOI: 10.1111/Febs.14351 |
0.487 |
|
2017 |
Kim JH, Hedrick S, Tsai WW, Wiater E, Le Lay J, Kaestner KH, Leblanc M, Loar A, Montminy M. CREB coactivators CRTC2 and CRTC3 modulate bone marrow hematopoiesis. Proceedings of the National Academy of Sciences of the United States of America. PMID 29078378 DOI: 10.1073/Pnas.1712616114 |
0.45 |
|
2017 |
Sonntag T, Moresco JJ, Vaughan JM, Matsumura S, Yates JR, Montminy M. Analysis of a cAMP regulated coactivator family reveals an alternative phosphorylation motif for AMPK family members. Plos One. 12: e0173013. PMID 28235073 DOI: 10.1371/Journal.Pone.0173013 |
0.441 |
|
2016 |
Shen R, Wang B, Giribaldi MG, Ayres J, Thomas JB, Montminy M. Neuronal energy-sensing pathway promotes energy balance by modulating disease tolerance. Proceedings of the National Academy of Sciences of the United States of America. PMID 27208092 DOI: 10.1073/Pnas.1606106113 |
0.45 |
|
2016 |
Ravnskjaer K, Madiraju A, Montminy M. Role of the cAMP Pathway in Glucose and Lipid Metabolism. Handbook of Experimental Pharmacology. 233: 29-49. PMID 26721678 DOI: 10.1007/164_2015_32 |
0.493 |
|
2015 |
Luan B, Yoon YS, Le Lay J, Kaestner KH, Hedrick S, Montminy M. CREB pathway links PGE2 signaling with macrophage polarization. Proceedings of the National Academy of Sciences of the United States of America. PMID 26644581 DOI: 10.1073/pnas.1519644112 |
0.357 |
|
2015 |
Hogan MF, Ravnskjaer K, Matsumura S, Huising MO, Hull RL, Kahn SE, Montminy M. Hepatic Insulin Resistance Following Chronic Activation of the CREB Coactivator CRTC2. The Journal of Biological Chemistry. 290: 25997-6006. PMID 26342077 DOI: 10.1074/Jbc.M115.679266 |
0.518 |
|
2015 |
Hernandez JB, Chang C, LeBlanc M, Grimm D, Le Lay J, Kaestner KH, Zheng Y, Montminy M. The CREB/CRTC2 pathway modulates autoimmune disease by promoting Th17 differentiation. Nature Communications. 6: 7216. PMID 26031354 DOI: 10.1038/Ncomms8216 |
0.313 |
|
2015 |
Tsai WW, Matsumura S, Liu W, Phillips NG, Sonntag T, Hao E, Lee S, Hai T, Montminy M. ATF3 mediates inhibitory effects of ethanol on hepatic gluconeogenesis. Proceedings of the National Academy of Sciences of the United States of America. 112: 2699-704. PMID 25730876 DOI: 10.1073/Pnas.1424641112 |
0.408 |
|
2015 |
Blanchet E, Van de Velde S, Matsumura S, Hao E, LeLay J, Kaestner K, Montminy M. Feedback inhibition of CREB signaling promotes beta cell dysfunction in insulin resistance. Cell Reports. 10: 1149-57. PMID 25704817 DOI: 10.1016/J.Celrep.2015.01.046 |
0.46 |
|
2014 |
Paz JC, Park S, Phillips N, Matsumura S, Tsai WW, Kasper L, Brindle PK, Zhang G, Zhou MM, Wright PE, Montminy M. Combinatorial regulation of a signal-dependent activator by phosphorylation and acetylation. Proceedings of the National Academy of Sciences of the United States of America. 111: 17116-21. PMID 25404345 DOI: 10.1073/Pnas.1420389111 |
0.552 |
|
2014 |
Luan B, Goodarzi MO, Phillips NG, Guo X, Chen YD, Yao J, Allison M, Rotter JI, Shaw R, Montminy M. Leptin-mediated increases in catecholamine signaling reduce adipose tissue inflammation via activation of macrophage HDAC4. Cell Metabolism. 19: 1058-65. PMID 24768298 DOI: 10.1016/J.Cmet.2014.03.024 |
0.496 |
|
2013 |
Ravnskjaer K, Hogan MF, Lackey D, Tora L, Dent SY, Olefsky J, Montminy M. Glucagon regulates gluconeogenesis through KAT2B- and WDR5-mediated epigenetic effects. The Journal of Clinical Investigation. 123: 4318-28. PMID 24051374 DOI: 10.1172/Jci69035 |
0.53 |
|
2013 |
Tsai WW, Niessen S, Goebel N, Yates JR, Guccione E, Montminy M. PRMT5 modulates the metabolic response to fasting signals. Proceedings of the National Academy of Sciences of the United States of America. 110: 8870-5. PMID 23671120 DOI: 10.1073/Pnas.1304602110 |
0.577 |
|
2013 |
Yu J, Deng R, Zhu HH, Zhang SS, Zhu C, Montminy M, Davis R, Feng GS. Modulation of fatty acid synthase degradation by concerted action of p38 MAP kinase, E3 ligase COP1, and SH2-tyrosine phosphatase Shp2. The Journal of Biological Chemistry. 288: 3823-30. PMID 23269672 DOI: 10.1074/Jbc.M112.397885 |
0.448 |
|
2012 |
Luo Q, Viste K, Urday-Zaa JC, Senthil Kumar G, Tsai WW, Talai A, Mayo KE, Montminy M, Radhakrishnan I. Mechanism of CREB recognition and coactivation by the CREB-regulated transcriptional coactivator CRTC2. Proceedings of the National Academy of Sciences of the United States of America. 109: 20865-70. PMID 23213254 DOI: 10.1073/Pnas.1219028109 |
0.444 |
|
2012 |
Wang Y, Li G, Goode J, Paz JC, Ouyang K, Screaton R, Fischer WH, Chen J, Tabas I, Montminy M. Inositol-1,4,5-trisphosphate receptor regulates hepatic gluconeogenesis in fasting and diabetes. Nature. 485: 128-32. PMID 22495310 DOI: 10.1038/Nature10988 |
0.794 |
|
2011 |
Van de Velde S, Hogan MF, Montminy M. mTOR links incretin signaling to HIF induction in pancreatic beta cells. Proceedings of the National Academy of Sciences of the United States of America. 108: 16876-82. PMID 21949366 DOI: 10.1073/Pnas.1114228108 |
0.415 |
|
2011 |
Stewart R, Flechner L, Montminy M, Berdeaux R. CREB is activated by muscle injury and promotes muscle regeneration. Plos One. 6: e24714. PMID 21931825 DOI: 10.1371/Journal.Pone.0024714 |
0.736 |
|
2011 |
Mihaylova MM, Vasquez DS, Ravnskjaer K, Denechaud PD, Yu RT, Alvarez JG, Downes M, Evans RM, Montminy M, Shaw RJ. Class IIa histone deacetylases are hormone-activated regulators of FOXO and mammalian glucose homeostasis. Cell. 145: 607-21. PMID 21565617 DOI: 10.1016/J.Cell.2011.03.043 |
0.453 |
|
2011 |
Wang B, Moya N, Niessen S, Hoover H, Mihaylova MM, Shaw RJ, Yates JR, Fischer WH, Thomas JB, Montminy M. A hormone-dependent module regulating energy balance. Cell. 145: 596-606. PMID 21565616 DOI: 10.1016/J.Cell.2011.04.013 |
0.537 |
|
2011 |
Altarejos JY, Montminy M. CREB and the CRTC co-activators: sensors for hormonal and metabolic signals. Nature Reviews. Molecular Cell Biology. 12: 141-51. PMID 21346730 DOI: 10.1038/Nrm3072 |
0.541 |
|
2011 |
Mair W, Morantte I, Rodrigues AP, Manning G, Montminy M, Shaw RJ, Dillin A. Lifespan extension induced by AMPK and calcineurin is mediated by CRTC-1 and CREB. Nature. 470: 404-8. PMID 21331044 DOI: 10.1038/Nature09706 |
0.458 |
|
2011 |
Montminy M, Ferreri K. Cyclic Adenosine Monophosphate Regulation of Gene Transcription Comprehensive Physiology. DOI: 10.1002/Cphy.Cp070113 |
0.452 |
|
2010 |
Song Y, Altarejos J, Goodarzi MO, Inoue H, Guo X, Berdeaux R, Kim JH, Goode J, Igata M, Paz JC, Hogan MF, Singh PK, Goebel N, Vera L, Miller N, ... ... Montminy M, et al. CRTC3 links catecholamine signalling to energy balance. Nature. 468: 933-9. PMID 21164481 DOI: 10.1038/Nature09564 |
0.778 |
|
2010 |
Yoon YS, Lee MW, Ryu D, Kim JH, Ma H, Seo WY, Kim YN, Kim SS, Lee CH, Hunter T, Choi CS, Montminy MR, Koo SH. Suppressor of MEK null (SMEK)/protein phosphatase 4 catalytic subunit (PP4C) is a key regulator of hepatic gluconeogenesis. Proceedings of the National Academy of Sciences of the United States of America. 107: 17704-9. PMID 20876121 DOI: 10.1073/Pnas.1012665107 |
0.461 |
|
2010 |
Zhang EE, Liu Y, Dentin R, Pongsawakul PY, Liu AC, Hirota T, Nusinow DA, Sun X, Landais S, Kodama Y, Brenner DA, Montminy M, Kay SA. Cryptochrome mediates circadian regulation of cAMP signaling and hepatic gluconeogenesis. Nature Medicine. 16: 1152-6. PMID 20852621 DOI: 10.1038/Nm.2214 |
0.571 |
|
2010 |
Zmuda EJ, Qi L, Zhu MX, Mirmira RG, Montminy MR, Hai T. The roles of ATF3, an adaptive-response gene, in high-fat-diet-induced diabetes and pancreatic beta-cell dysfunction. Molecular Endocrinology (Baltimore, Md.). 24: 1423-33. PMID 20519332 DOI: 10.1210/Me.2009-0463 |
0.51 |
|
2010 |
Wang Y, Inoue H, Ravnskjaer K, Viste K, Miller N, Liu Y, Hedrick S, Vera L, Montminy M. Targeted disruption of the CREB coactivator Crtc2 increases insulin sensitivity. Proceedings of the National Academy of Sciences of the United States of America. 107: 3087-92. PMID 20133702 DOI: 10.1073/Pnas.0914897107 |
0.501 |
|
2009 |
Wang Y, Vera L, Fischer WH, Montminy M. The CREB coactivator CRTC2 links hepatic ER stress and fasting gluconeogenesis. Nature. 460: 534-7. PMID 19543265 DOI: 10.1038/Nature08111 |
0.434 |
|
2009 |
Qi L, Saberi M, Zmuda E, Wang Y, Altarejos J, Zhang X, Dentin R, Hedrick S, Bandyopadhyay G, Hai T, Olefsky J, Montminy M. Adipocyte CREB promotes insulin resistance in obesity. Cell Metabolism. 9: 277-86. PMID 19254572 DOI: 10.1016/J.Cmet.2009.01.006 |
0.609 |
|
2009 |
Ryu D, Oh KJ, Jo HY, Hedrick S, Kim YN, Hwang YJ, Park TS, Han JS, Choi CS, Montminy M, Koo SH. TORC2 regulates hepatic insulin signaling via a mammalian phosphatidic acid phosphatase, LIPIN1. Cell Metabolism. 9: 240-51. PMID 19254569 DOI: 10.1016/J.Cmet.2009.01.007 |
0.484 |
|
2009 |
Altarejos J, Goebel N, Conkright M, Inoue H, Xie J, Arias C, Sawchenko P, Montminy M. Reply to: Mouse fertility is not dependent on the CREB coactivator Crtc1 Nature Medicine. 15: 991. DOI: 10.1038/Nm0909-991A |
0.325 |
|
2008 |
Liu Y, Dentin R, Chen D, Hedrick S, Ravnskjaer K, Schenk S, Milne J, Meyers DJ, Cole P, Yates J, Olefsky J, Guarente L, Montminy M. A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange. Nature. 456: 269-73. PMID 18849969 DOI: 10.1038/Nature07349 |
0.536 |
|
2008 |
Altarejos JY, Goebel N, Conkright MD, Inoue H, Xie J, Arias CM, Sawchenko PE, Montminy M. The Creb1 coactivator Crtc1 is required for energy balance and fertility. Nature Medicine. 14: 1112-7. PMID 18758446 DOI: 10.1093/Biolreprod/83.S1.196 |
0.494 |
|
2008 |
Wang B, Goode J, Best J, Meltzer J, Schilman PE, Chen J, Garza D, Thomas JB, Montminy M. The insulin-regulated CREB coactivator TORC promotes stress resistance in Drosophila. Cell Metabolism. 7: 434-44. PMID 18460334 DOI: 10.1016/J.Cmet.2008.02.010 |
0.799 |
|
2008 |
Dentin R, Hedrick S, Xie J, Yates J, Montminy M. Hepatic glucose sensing via the CREB coactivator CRTC2. Science (New York, N.Y.). 319: 1402-5. PMID 18323454 DOI: 10.1126/Science.1151363 |
0.381 |
|
2007 |
Dentin R, Liu Y, Koo SH, Hedrick S, Vargas T, Heredia J, Yates J, Montminy M. Insulin modulates gluconeogenesis by inhibition of the coactivator TORC2. Nature. 449: 366-9. PMID 17805301 DOI: 10.1038/Nature06128 |
0.817 |
|
2007 |
Ravnskjaer K, Kester H, Liu Y, Zhang X, Lee D, Yates JR, Montminy M. Cooperative interactions between CBP and TORC2 confer selectivity to CREB target gene expression. The Embo Journal. 26: 2880-9. PMID 17476304 DOI: 10.1038/Sj.Emboj.7601715 |
0.48 |
|
2007 |
Berdeaux R, Goebel N, Banaszynski L, Takemori H, Wandless T, Shelton GD, Montminy M. SIK1 is a class II HDAC kinase that promotes survival of skeletal myocytes. Nature Medicine. 13: 597-603. PMID 17468767 DOI: 10.1038/Nm1573 |
0.437 |
|
2007 |
Montminy M, Dentin R, Liu Y, Hedrick S. The TORC family of CREB coactivators: Regulators of energy balance The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A45-A |
0.302 |
|
2006 |
Koo SH, Montminy M. In vino veritas: a tale of two sirt1s? Cell. 127: 1091-3. PMID 17174885 DOI: 10.1016/J.Cell.2006.11.034 |
0.336 |
|
2006 |
Qi L, Heredia JE, Altarejos JY, Screaton R, Goebel N, Niessen S, Macleod IX, Liew CW, Kulkarni RN, Bain J, Newgard C, Nelson M, Evans RM, Yates J, Montminy M. TRB3 links the E3 ubiquitin ligase COP1 to lipid metabolism. Science (New York, N.Y.). 312: 1763-6. PMID 16794074 DOI: 10.1126/Science.1123374 |
0.768 |
|
2006 |
Liu Y, Montminy M. CAT in the HAT: catabolic inhibition by the histone acetyltransferase GCN5. Cell Metabolism. 3: 387-8. PMID 16753572 DOI: 10.1016/J.Cmet.2006.05.006 |
0.329 |
|
2006 |
Cho CY, Koo SH, Wang Y, Callaway S, Hedrick S, Mak PA, Orth AP, Peters EC, Saez E, Montminy M, Schultz PG, Chanda SK. Identification of the tyrosine phosphatase PTP-MEG2 as an antagonist of hepatic insulin signaling. Cell Metabolism. 3: 367-78. PMID 16679294 DOI: 10.1016/J.Cmet.2006.03.006 |
0.464 |
|
2006 |
Zhang W, Patil S, Chauhan B, Guo S, Powell DR, Le J, Klotsas A, Matika R, Xiao X, Franks R, Heidenreich KA, Sajan MP, Farese RV, Stolz DB, Tso P, ... ... Montminy M, et al. FoxO1 regulates multiple metabolic pathways in the liver: effects on gluconeogenic, glycolytic, and lipogenic gene expression. The Journal of Biological Chemistry. 281: 10105-17. PMID 16492665 DOI: 10.1074/Jbc.M600272200 |
0.513 |
|
2006 |
Koo SH, Montminy M. Fatty acids and insulin resistance: a perfect storm. Molecular Cell. 21: 449-50. PMID 16483925 DOI: 10.1016/J.Molcel.2006.02.001 |
0.381 |
|
2005 |
Shaw RJ, Lamia KA, Vasquez D, Koo SH, Bardeesy N, Depinho RA, Montminy M, Cantley LC. The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin. Science (New York, N.Y.). 310: 1642-6. PMID 16308421 DOI: 10.1126/Science.1120781 |
0.494 |
|
2005 |
Canettieri G, Koo SH, Berdeaux R, Heredia J, Hedrick S, Zhang X, Montminy M. Dual role of the coactivator TORC2 in modulating hepatic glucose output and insulin signaling. Cell Metabolism. 2: 331-8. PMID 16271533 DOI: 10.1016/J.Cmet.2005.09.008 |
0.792 |
|
2005 |
Park JM, Greten FR, Wong A, Westrick RJ, Arthur JS, Otsu K, Hoffmann A, Montminy M, Karin M. Signaling pathways and genes that inhibit pathogen-induced macrophage apoptosis--CREB and NF-kappaB as key regulators. Immunity. 23: 319-29. PMID 16169504 DOI: 10.1016/J.Immuni.2005.08.010 |
0.391 |
|
2005 |
Gardner KH, Montminy M. Can you hear me now? Regulating transcriptional activators by phosphorylation. Science's Stke : Signal Transduction Knowledge Environment. 2005: pe44. PMID 16160121 DOI: 10.1126/Stke.3012005Pe44 |
0.477 |
|
2005 |
Koo SH, Flechner L, Qi L, Zhang X, Screaton RA, Jeffries S, Hedrick S, Xu W, Boussouar F, Brindle P, Takemori H, Montminy M. The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism. Nature. 437: 1109-11. PMID 16148943 DOI: 10.1038/Nature03967 |
0.816 |
|
2005 |
Conkright MD, Montminy M. CREB: the unindicted cancer co-conspirator. Trends in Cell Biology. 15: 457-9. PMID 16084096 DOI: 10.1016/J.Tcb.2005.07.007 |
0.419 |
|
2005 |
Zhang X, Odom DT, Koo SH, Conkright MD, Canettieri G, Best J, Chen H, Jenner R, Herbolsheimer E, Jacobsen E, Kadam S, Ecker JR, Emerson B, Hogenesch JB, Unterman T, ... ... Montminy M, et al. Genome-wide analysis of cAMP-response element binding protein occupancy, phosphorylation, and target gene activation in human tissues. Proceedings of the National Academy of Sciences of the United States of America. 102: 4459-64. PMID 15753290 DOI: 10.1073/Pnas.0501076102 |
0.521 |
|
2005 |
Mayr BM, Guzman E, Montminy M. Glutamine rich and basic region/leucine zipper (bZIP) domains stabilize cAMP-response element-binding protein (CREB) binding to chromatin. The Journal of Biological Chemistry. 280: 15103-10. PMID 15703171 DOI: 10.1074/Jbc.M414144200 |
0.422 |
|
2004 |
Montminy M, Koo SH. Diabetes: outfoxing insulin resistance? Nature. 432: 958-9. PMID 15616540 DOI: 10.1038/432958A |
0.356 |
|
2004 |
Best JL, Amezcua CA, Mayr B, Flechner L, Murawsky CM, Emerson B, Zor T, Gardner KH, Montminy M. Identification of small-molecule antagonists that inhibit an activator: coactivator interaction. Proceedings of the National Academy of Sciences of the United States of America. 101: 17622-7. PMID 15585582 DOI: 10.1073/Pnas.0406374101 |
0.763 |
|
2004 |
Screaton RA, Conkright MD, Katoh Y, Best JL, Canettieri G, Jeffries S, Guzman E, Niessen S, Yates JR, Takemori H, Okamoto M, Montminy M. The CREB coactivator TORC2 functions as a calcium- and cAMP-sensitive coincidence detector. Cell. 119: 61-74. PMID 15454081 DOI: 10.1016/J.Cell.2004.09.015 |
0.487 |
|
2004 |
Kulkarni RN, Jhala US, Winnay JN, Krajewski S, Montminy M, Kahn CR. PDX-1 haploinsufficiency limits the compensatory islet hyperplasia that occurs in response to insulin resistance. The Journal of Clinical Investigation. 114: 828-36. PMID 15372107 DOI: 10.1172/Jci21845 |
0.366 |
|
2004 |
Montminy M, Koo SH, Zhang X. The CREB Family: Key regulators of hepatic metabolism Annales D'Endocrinologie. 65: 73-75. PMID 15122096 DOI: 10.1016/S0003-4266(04)95634-X |
0.314 |
|
2004 |
Koo SH, Satoh H, Herzig S, Lee CH, Hedrick S, Kulkarni R, Evans RM, Olefsky J, Montminy M. PGC-1 promotes insulin resistance in liver through PPAR-alpha-dependent induction of TRB-3. Nature Medicine. 10: 530-4. PMID 15107844 DOI: 10.1038/Nm1044 |
0.468 |
|
2004 |
Koo S, Satoh H, Herzig S, Lee C, Hedrick S, Kulkarni R, Evans RM, Olefsky J, Montminy M. Erratum: PGC-1 promotes insulin resistance in liver through PPAR-α-dependent induction of TRB-3 Nature Medicine. 10: 755-755. DOI: 10.1038/Nm0704-755A |
0.372 |
|
2003 |
Herzig S, Hedrick S, Morantte I, Koo SH, Galimi F, Montminy M. CREB controls hepatic lipid metabolism through nuclear hormone receptor PPAR-gamma. Nature. 426: 190-3. PMID 14614508 DOI: 10.1038/Nature02110 |
0.506 |
|
2003 |
Conkright MD, Canettieri G, Screaton R, Guzman E, Miraglia L, Hogenesch JB, Montminy M. TORCs: transducers of regulated CREB activity. Molecular Cell. 12: 413-23. PMID 14536081 DOI: 10.1016/J.Molcel.2003.08.013 |
0.501 |
|
2003 |
Jhala US, Canettieri G, Screaton RA, Kulkarni RN, Krajewski S, Reed J, Walker J, Lin X, White M, Montminy M. cAMP promotes pancreatic beta-cell survival via CREB-mediated induction of IRS2. Genes & Development. 17: 1575-80. PMID 12842910 DOI: 10.1101/Gad.1097103 |
0.46 |
|
2003 |
Du K, Herzig S, Kulkarni RN, Montminy M. TRB3: a tribbles homolog that inhibits Akt/PKB activation by insulin in liver. Science (New York, N.Y.). 300: 1574-7. PMID 12791994 DOI: 10.1126/Science.1079817 |
0.477 |
|
2003 |
Conkright MD, Guzmán E, Flechner L, Su AI, Hogenesch JB, Montminy M. Genome-wide analysis of CREB target genes reveals a core promoter requirement for cAMP responsiveness. Molecular Cell. 11: 1101-8. PMID 12718894 DOI: 10.1016/S1097-2765(03)00134-5 |
0.765 |
|
2003 |
Canettieri G, Morantte I, Guzmán E, Asahara H, Herzig S, Anderson SD, Yates JR, Montminy M. Attenuation of a phosphorylation-dependent activator by an HDAC-PP1 complex. Nature Structural Biology. 10: 175-81. PMID 12567184 DOI: 10.1038/Nsb895 |
0.463 |
|
2003 |
Montminy M, Du K. Transcriptional Regulation via the cAMP Responsive Activator CREB Handbook of Cell Signaling. 3: 115-118. DOI: 10.1016/B978-012124546-7/50649-5 |
0.345 |
|
2002 |
Zor T, Mayr BM, Dyson HJ, Montminy MR, Wright PE. Roles of phosphorylation and helix propensity in the binding of the KIX domain of CREB-binding protein by constitutive (c-Myb) and inducible (CREB) activators. The Journal of Biological Chemistry. 277: 42241-8. PMID 12196545 DOI: 10.1074/Jbc.M207361200 |
0.301 |
|
2002 |
Asahara H, Tartare-Deckert S, Nakagawa T, Ikehara T, Hirose F, Hunter T, Ito T, Montminy M. Dual roles of p300 in chromatin assembly and transcriptional activation in cooperation with nucleosome assembly protein 1 in vitro. Molecular and Cellular Biology. 22: 2974-83. PMID 11940655 DOI: 10.1128/Mcb.22.9.2974-2983.2002 |
0.321 |
|
2001 |
Xu W, Chen H, Du K, Asahara H, Tini M, Emerson BM, Montminy M, Evans RM. A transcriptional switch mediated by cofactor methylation. Science (New York, N.Y.). 294: 2507-11. PMID 11701890 DOI: 10.1126/Science.1065961 |
0.406 |
|
2001 |
Asahara H, Santoso B, Guzman E, Du K, Cole PA, Davidson I, Montminy M. Chromatin-dependent cooperativity between constitutive and inducible activation domains in CREB. Molecular and Cellular Biology. 21: 7892-900. PMID 11689682 DOI: 10.1128/Mcb.21.23.7892-7900.2001 |
0.438 |
|
2001 |
Herzig S, Long F, Jhala US, Hedrick S, Quinn R, Bauer A, Rudolph D, Schutz G, Yoon C, Puigserver P, Spiegelman B, Montminy M. CREB regulates hepatic gluconeogenesis through the coactivator PGC-1. Nature. 413: 179-83. PMID 11557984 DOI: 10.1038/35093131 |
0.54 |
|
2001 |
Mayr B, Montminy M. Transcriptional regulation by the phosphorylation-dependent factor CREB. Nature Reviews. Molecular Cell Biology. 2: 599-609. PMID 11483993 DOI: 10.1038/35085068 |
0.473 |
|
2001 |
Dutta S, Gannon M, Peers B, Wright C, Bonner-Weir S, Montminy M. PDX:PBX complexes are required for normal proliferation of pancreatic cells during development Proceedings of the National Academy of Sciences. 98: 1065-1070. DOI: 10.1073/Pnas.98.3.1065 |
0.369 |
|
2001 |
Herzig S, Long F, Jhala US, Hedrick S, Quinn R, Bauer A, Rudolph D, Schutz G, Yoon C, Puigserver P, Spiegelman B, Montminy M. Erratum: correction: CREB regulates hepatic gluconeogenesis through the coactivator PGC-1 Nature. 413: 652-652. DOI: 10.1038/35098123 |
0.454 |
|
2000 |
von Mikecz A, Zhang S, Montminy M, Tan EM, Hemmerich P. CREB-binding protein (CBP)/p300 and RNA polymerase II colocalize in transcriptionally active domains in the nucleus. The Journal of Cell Biology. 150: 265-73. PMID 10893273 DOI: 10.1083/Jcb.150.1.265 |
0.367 |
|
2000 |
Du K, Asahara H, Jhala US, Wagner BL, Montminy M. Characterization of a CREB gain-of-function mutant with constitutive transcriptional activity in vivo. Molecular and Cellular Biology. 20: 4320-7. PMID 10825195 DOI: 10.1128/Mcb.20.12.4320-4327.2000 |
0.523 |
|
2000 |
Wagner BL, Bauer A, Schütz G, Montminy M. Stimulus-specific interaction between activator-coactivator cognates revealed with a novel complex-specific antiserum. The Journal of Biological Chemistry. 275: 8263-6. PMID 10722651 DOI: 10.1074/Jbc.275.12.8263 |
0.416 |
|
2000 |
Michael LF, Asahara H, Shulman AI, Kraus WL, Montminy M. The phosphorylation status of a cyclic AMP-responsive activator is modulated via a chromatin-dependent mechanism. Molecular and Cellular Biology. 20: 1596-603. PMID 10669737 DOI: 10.1128/Mcb.20.5.1596-1603.2000 |
0.491 |
|
1999 |
Asahara H, Dutta S, Kao HY, Evans RM, Montminy M. Pbx-Hox heterodimers recruit coactivator-corepressor complexes in an isoform-specific manner. Molecular and Cellular Biology. 19: 8219-25. PMID 10567547 DOI: 10.1128/Mcb.19.12.8219 |
0.426 |
|
1999 |
Malecki MT, Jhala US, Antonellis A, Fields L, Doria A, Orban T, Saad M, Warram JH, Montminy M, Krolewski AS. Mutations in NEUROD1 are associated with the development of type 2 diabetes mellitus Nature Genetics. 23: 323-328. PMID 10545951 DOI: 10.1038/15500 |
0.395 |
|
1999 |
Parker D, Rivera M, Zor T, Henrion-Caude A, Radhakrishnan I, Kumar A, Shapiro LH, Wright PE, Montminy M, Brindle PK. Role of secondary structure in discrimination between constitutive and inducible activators. Molecular and Cellular Biology. 19: 5601-7. PMID 10409749 DOI: 10.1128/Mcb.19.8.5601 |
0.394 |
|
1998 |
Du K, Montminy M. CREB is a regulatory target for the protein kinase Akt/PKB Journal of Biological Chemistry. 273: 32377-32379. PMID 9829964 DOI: 10.1074/Jbc.273.49.32377 |
0.494 |
|
1998 |
Parker D, Jhala US, Radhakrishnan I, Yaffe MB, Reyes C, Shulman AI, Cantley LC, Wright PE, Montminy M. Analysis of an activator:coactivator complex reveals an essential role for secondary structure in transcriptional activation. Molecular Cell. 2: 353-9. PMID 9774973 DOI: 10.1016/S1097-2765(00)80279-8 |
0.478 |
|
1998 |
Blobel GA, Nakajima T, Eckner R, Montminy M, Orkin SH. CREB-binding protein cooperates with transcription factor GATA-1 and is required for erythroid differentiation Proceedings of the National Academy of Sciences of the United States of America. 95: 2061-2066. PMID 9482838 DOI: 10.1073/Pnas.95.5.2061 |
0.419 |
|
1997 |
Nakajima T, Uchida C, Anderson SF, Chee-Gun L, Hurwitz J, Parvin JD, Montminy M. RNA helicase A mediates association of CBP with RNA polymerase II Cell. 90: 1107-1112. PMID 9323138 DOI: 10.1016/S0092-8674(00)80376-1 |
0.335 |
|
1997 |
Montminy M. Transcriptional Regulation by Cyclic AMP Annual Review of Biochemistry. 66: 807-822. PMID 9242925 DOI: 10.1146/Annurev.Biochem.66.1.807 |
0.473 |
|
1997 |
Montminy M. Transcriptional activation. Something new to hang your HAT on. Nature. 387: 654-5. PMID 9192883 DOI: 10.1038/42594 |
0.371 |
|
1997 |
Sharma S, Jhala US, Johnson T, Ferreri K, Leonard J, Montminy M. Hormonal regulation of an islet-specific enhancer in the pancreatic homeobox gene STF-1. Molecular and Cellular Biology. 17: 2598-2604. PMID 9111329 DOI: 10.1128/Mcb.17.5.2598 |
0.379 |
|
1997 |
Nakajima T, Uchida C, Anderson SF, Parvin JD, Montminy M. Analysis of a cAMP-responsive activator reveals a two-component mechanism for transcriptional induction via signal-dependent factors. Genes & Development. 11: 738-47. PMID 9087428 DOI: 10.1101/Gad.11.6.738 |
0.45 |
|
1996 |
Chakravarti D, LaMorte VJ, Nelson MC, Nakajima T, Schulman IG, Juguilon H, Montminy M, Evans RM. Role of CBP/P300 in nuclear receptor signalling. Nature. 383: 99-103. PMID 8779723 DOI: 10.1038/383099A0 |
0.401 |
|
1996 |
Montminy M, Brindle P, Arias J, Ferreri K, Armstrong R. Regulation of somatostatin gene transcription by cyclic adenosine monophosphate Metabolism: Clinical and Experimental. 45: 4-7. PMID 8769368 DOI: 10.1016/S0026-0495(96)90068-2 |
0.503 |
|
1995 |
Peers B, Sharma S, Johnson T, Kamps M, Montminy M. The pancreatic islet factor STF-1 binds cooperatively with Pbx to a regulatory element in the somatostatin promoter: importance of the FPWMK motif and of the homeodomain. Molecular and Cellular Biology. 15: 7091-7. PMID 8524276 DOI: 10.1128/Mcb.15.12.7091 |
0.398 |
|
1995 |
Armstrong R, Wen W, Meinkoth J, Taylor S, Montminy M. A refractory phase in cyclic AMP-responsive transcription requires down regulation of protein kinase A. Molecular and Cellular Biology. 15: 1826-32. PMID 7862172 DOI: 10.1128/Mcb.15.3.1826 |
0.48 |
|
1995 |
Montminy M, Brindle P, Arias J, Ferreri K, Armstrong R. Regulation of somatostatin gene transcription by cAMP Ciba Foundation Symposium. 190: 7-20; discussion 20. PMID 7587654 DOI: 10.1016/S1054-3589(08)60573-6 |
0.53 |
|
1995 |
Brindle P, Nakajima T, Montminy M. Multiple protein kinase A-regulated events are required for transcriptional induction by cAMP Proceedings of the National Academy of Sciences of the United States of America. 92: 10521-10525. PMID 7479832 DOI: 10.1073/Pnas.92.23.10521 |
0.511 |
|
1995 |
Bertherat J, Chanson P, Montminy M. The cyclic adenosine 3',5'-monophosphate-responsive factor CREB is constitutively activated in human somatotroph adenomas. Molecular Endocrinology. 9: 777-783. PMID 7476961 DOI: 10.1210/Mend.9.7.7476961 |
0.425 |
|
1994 |
Arias J, Alberts AS, Brindle P, Claret FX, Smeal T, Karin M, Feramisco J, Montminy M. Activation of cAMP and mitogen responsive genes relies on a common nuclear factor. Nature. 370: 226-9. PMID 8028671 DOI: 10.1038/370226A0 |
0.538 |
|
1994 |
Ferreri K, Gill G, Montminy M. The cAMP-regulated transcription factor CREB interacts with a component of the TFIID complex Proceedings of the National Academy of Sciences of the United States of America. 91: 1210-1213. PMID 7906413 DOI: 10.1073/Pnas.91.4.1210 |
0.452 |
|
1994 |
Alberts AS, Montminy M, Shenolikar S, Feramisco JR. Expression of a peptide inhibitor of protein phosphatase 1 increases phosphorylation and activity of CREB in NIH 3T3 fibroblasts. Molecular and Cellular Biology. 14: 4398-407. PMID 7516466 DOI: 10.1128/Mcb.14.7.4398 |
0.47 |
|
1993 |
Brindle P, Linke S, Montminy M. Protein-kinase-A-dependent activator in transcription factor CREB reveals new role for CREM repressors Nature. 364: 821-824. PMID 8102791 DOI: 10.1038/364821A0 |
0.484 |
|
1993 |
Meinkoth JL, Alberts AS, Went W, Fantozzi D, Taylor SS, Hagiwara M, Montminy M, Feramisco JR. Signal transduction through the cAMP-dependent protein kinase. Molecular and Cellular Biochemistry. 127: 179-86. PMID 7935349 DOI: 10.1007/Bf01076769 |
0.42 |
|
1992 |
Leonard J, Serup P, Gonzalez G, Edlund T, Montminy M. The LIM family transcription factor Isl-1 requires cAMP response element binding protein to promote somatostatin expression in pancreatic islet cells Proceedings of the National Academy of Sciences of the United States of America. 89: 6247-6251. PMID 1352885 DOI: 10.1073/Pnas.89.14.6247 |
0.504 |
|
1992 |
Hagiwara M, Alberts A, Brindle P, Meinkoth J, Feramisco J, Deng T, Karin M, Shenolikar S, Montminy M. Transcriptional attenuation following cAMP induction requires PP-1-mediated dephosphorylation of CREB. Cell. 70: 105-13. PMID 1352481 DOI: 10.1016/0092-8674(92)90537-M |
0.493 |
|
1990 |
Lamph WW, Dwarki VJ, Ofir R, Montminy M, Verma IM. Negative and positive regulation by transcription factor cAMP response element-binding protein is modulated by phosphorylation. Proceedings of the National Academy of Sciences of the United States of America. 87: 4320-4. PMID 2140898 DOI: 10.1073/Pnas.87.11.4320 |
0.479 |
|
1990 |
Dwarki V, Montminy M, Verma I. Both the basic region and the ‘leucine zipper’ domain of the cyclic AMP response element binding (CREB) protein are essential for transcriptional activation. The Embo Journal. 9: 225-232. DOI: 10.1002/J.1460-2075.1990.Tb08099.X |
0.433 |
|
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