Joel G. Belasco - Publications

Affiliations: 
Biology New York University, New York, NY, United States 
Area:
Microbiology Biology

88 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Richards J, Belasco JG. Graded impact of obstacle size on scanning by RNase E. Nucleic Acids Research. PMID 36620905 DOI: 10.1093/nar/gkac1242  0.471
2022 Richards J, Belasco JG. PABLO-QA: A sensitive assay for quantifying monophosphorylated RNA 5' ends. Star Protocols. 3: 101190. PMID 35434657 DOI: 10.1016/j.xpro.2022.101190  0.403
2022 Levenson-Palmer R, Luciano DJ, Vasilyev N, Nuthanakanti A, Serganov A, Belasco JG. A distinct RNA recognition mechanism governs Np decapping by RppH. Proceedings of the National Academy of Sciences of the United States of America. 119. PMID 35131855 DOI: 10.1073/pnas.2117318119  0.399
2021 Hui MP, Belasco JG. Multifaceted impact of a nucleoside monophosphate kinase on 5'-end-dependent mRNA degradation in bacteria. Nucleic Acids Research. PMID 34643703 DOI: 10.1093/nar/gkab884  0.527
2021 Richards J, Belasco JG. Riboswitch control of bacterial RNA stability. Molecular Microbiology. PMID 33797153 DOI: 10.1111/mmi.14723  0.479
2020 Richards J, Belasco JG. Widespread Protection of RNA Cleavage Sites by a Riboswitch Aptamer that Folds as a Compact Obstacle to Scanning by RNase E. Molecular Cell. PMID 33212019 DOI: 10.1016/j.molcel.2020.10.025  0.496
2020 Luciano DJ, Belasco JG. NpA alarmones function in bacteria as precursors to RNA caps. Proceedings of the National Academy of Sciences of the United States of America. PMID 32019889 DOI: 10.1073/Pnas.1914229117  0.534
2019 Luciano DJ, Levenson-Palmer R, Belasco JG. Stresses that Raise NpA Levels Induce Protective Nucleoside Tetraphosphate Capping of Bacterial RNA. Molecular Cell. PMID 31178354 DOI: 10.1016/J.Molcel.2019.05.031  0.547
2019 Richards J, Belasco JG. Obstacles to Scanning by RNase E Govern Bacterial mRNA Lifetimes by Hindering Access to Distal Cleavage Sites. Molecular Cell. PMID 30852060 DOI: 10.1016/J.Molcel.2019.01.044  0.616
2018 Luciano DJ, Belasco JG. Analysis of RNA 5' ends: phosphate enumeration and cap characterization. Methods (San Diego, Calif.). PMID 30419334 DOI: 10.1016/J.Ymeth.2018.10.023  0.54
2018 Gao A, Vasilyev N, Luciano DJ, Levenson-Palmer R, Richards J, Marsiglia WM, Traaseth NJ, Belasco JG, Serganov A. Structural and kinetic insights into stimulation of RppH-dependent RNA degradation by the metabolic enzyme DapF. Nucleic Acids Research. PMID 29733359 DOI: 10.1093/Nar/Gky327  0.554
2018 Luciano DJ, Vasilyev N, Richards J, Serganov A, Belasco JG. Importance of a diphosphorylated intermediate for RppH-dependent RNA degradation. Rna Biology. 1-15. PMID 29619898 DOI: 10.1080/15476286.2018.1460995  0.658
2017 Lodato PB, Thuraisamy T, Richards J, Belasco JG. Effect of RNase E deficiency on translocon protein synthesis in an RNase E-inducible strain of enterohemorrhagic Escherichia coli O157:H7. Fems Microbiology Letters. 364. PMID 28854682 DOI: 10.1093/Femsle/Fnx131  0.48
2017 Luciano DJ, Vasilyev N, Richards J, Serganov A, Belasco JG. A Novel RNA Phosphorylation State Enables 5' End-Dependent Degradation in Escherichia coli. Molecular Cell. PMID 28673541 DOI: 10.1016/J.Molcel.2017.05.035  0.612
2017 Belasco JG. Death by translation: ribosome-assisted degradation of mRNA by endonuclease toxins. Febs Letters. PMID 28649728 DOI: 10.1002/1873-3468.12715  0.426
2017 Belasco JG. Ribonuclease E: Chopping Knife and Sculpting Tool. Molecular Cell. 65: 3-4. PMID 28061331 DOI: 10.1016/J.Molcel.2016.12.015  0.506
2016 Bischler T, Hsieh PK, Resch M, Liu Q, Tan HS, Foley PL, Hartleib A, Sharma CM, Belasco JG. Identification of the RNA Pyrophosphohydrolase RppH of Helicobacter pylori and Global Analysis of Its RNA Targets. The Journal of Biological Chemistry. PMID 27974459 DOI: 10.1074/Jbc.M116.761171  0.564
2016 Richards J, Belasco JG. Distinct requirements for 5'-monophosphate-assisted RNA cleavage by Escherichia coli RNase E and RNase G. The Journal of Biological Chemistry. 291: 20825. PMID 27664066 DOI: 10.1074/jbc.A115.702555  0.493
2016 Richards J, Belasco JG. Distinct Requirements for 5'-Monophosphate-assisted RNA Cleavage by Escherichia coli RNase E and RNase G. The Journal of Biological Chemistry. 291: 5038-48. PMID 26694614 DOI: 10.1074/Jbc.M115.702555  0.579
2015 Luciano DJ, Belasco JG. NAD in RNA: unconventional headgear. Trends in Biochemical Sciences. 40: 245-7. PMID 25801053 DOI: 10.1016/J.Tibs.2015.03.004  0.561
2015 Belasco JG. Way to go, RNA. Rna (New York, N.Y.). 21: 565-6. PMID 25780140 DOI: 10.1261/Rna.050773.115  0.668
2015 Foley PL, Hsieh PK, Luciano DJ, Belasco JG. Specificity and evolutionary conservation of the Escherichia coli RNA pyrophosphohydrolase RppH. The Journal of Biological Chemistry. 290: 9478-86. PMID 25657006 DOI: 10.1074/Jbc.M114.634659  0.586
2015 Schmidt SA, Foley PL, Jeong DH, Rymarquis LA, Doyle F, Tenenbaum SA, Belasco JG, Green PJ. Identification of SMG6 cleavage sites and a preferred RNA cleavage motif by global analysis of endogenous NMD targets in human cells. Nucleic Acids Research. 43: 309-23. PMID 25429978 DOI: 10.1093/Nar/Gku1258  0.499
2014 Hui MP, Foley PL, Belasco JG. Messenger RNA degradation in bacterial cells. Annual Review of Genetics. 48: 537-59. PMID 25292357 DOI: 10.1146/Annurev-Genet-120213-092340  0.609
2014 Vogel J, Gottesman S, Belasco J, Narberhaus F. Meeting report: Regulating with RNA in Bacteria 2013. Rna Biology. 11: 403-12. PMID 24922515 DOI: 10.4161/Rna.29533  0.503
2013 Hsieh PK, Richards J, Liu Q, Belasco JG. Specificity of RppH-dependent RNA degradation in Bacillus subtilis. Proceedings of the National Academy of Sciences of the United States of America. 110: 8864-9. PMID 23610425 DOI: 10.1073/Pnas.1222670110  0.56
2012 Lodato PB, Hsieh PK, Belasco JG, Kaper JB. The ribosome binding site of a mini-ORF protects a T3SS mRNA from degradation by RNase E. Molecular Microbiology. 86: 1167-82. PMID 23043360 DOI: 10.1111/Mmi.12050  0.568
2012 Richards J, Luciano DJ, Belasco JG. Influence of translation on RppH-dependent mRNA degradation in Escherichia coli. Molecular Microbiology. 86: 1063-72. PMID 22989003 DOI: 10.1111/Mmi.12040  0.556
2012 Luciano DJ, Hui MP, Deana A, Foley PL, Belasco KJ, Belasco JG. Differential control of the rate of 5'-end-dependent mRNA degradation in Escherichia coli. Journal of Bacteriology. 194: 6233-9. PMID 22984254 DOI: 10.1128/Jb.01223-12  0.493
2011 Richards J, Liu Q, Pellegrini O, Celesnik H, Yao S, Bechhofer DH, Condon C, Belasco JG. An RNA pyrophosphohydrolase triggers 5'-exonucleolytic degradation of mRNA in Bacillus subtilis. Molecular Cell. 43: 940-9. PMID 21925382 DOI: 10.1016/J.Molcel.2011.07.023  0.843
2011 Yao S, Richards J, Belasco JG, Bechhofer DH. Decay of a model mRNA in Bacillus subtilis by a combination of RNase J1 5' exonuclease and RNase Y endonuclease activities. Journal of Bacteriology. 193: 6384-6. PMID 21908660 DOI: 10.1128/Jb.05939-11  0.435
2010 Belasco JG. All things must pass: contrasts and commonalities in eukaryotic and bacterial mRNA decay. Nature Reviews. Molecular Cell Biology. 11: 467-78. PMID 20520623 DOI: 10.1038/Nrm2917  0.446
2010 Savas JN, Ma B, Deinhardt K, Culver BP, Restituito S, Wu L, Belasco JG, Chao MV, Tanese N. A role for huntington disease protein in dendritic RNA granules. The Journal of Biological Chemistry. 285: 13142-53. PMID 20185826 DOI: 10.1074/Jbc.M110.114561  0.698
2010 Piao X, Zhang X, Wu L, Belasco JG. CCR4-NOT deadenylates mRNA associated with RNA-induced silencing complexes in human cells. Molecular and Cellular Biology. 30: 1486-94. PMID 20065043 DOI: 10.1128/Mcb.01481-09  0.709
2009 Schuck A, Diwa A, Belasco JG. RNase E autoregulates its synthesis in Escherichia coli by binding directly to a stem-loop in the rne 5' untranslated region. Molecular Microbiology. 72: 470-8. PMID 19320830 DOI: 10.1111/J.1365-2958.2009.06662.X  0.759
2009 Messing SA, Gabelli SB, Liu Q, Celesnik H, Belasco JG, Piñeiro SA, Amzel LM. Structure and biological function of the RNA pyrophosphohydrolase BdRppH from Bdellovibrio bacteriovorus. Structure (London, England : 1993). 17: 472-81. PMID 19278661 DOI: 10.1016/J.Str.2008.12.022  0.814
2008 Wu L, Belasco JG. Examining the influence of microRNAs on translation efficiency and on mRNA deadenylation and decay. Methods in Enzymology. 449: 373-93. PMID 19215768 DOI: 10.1016/S0076-6879(08)02418-X  0.659
2008 Celesnik H, Deana A, Belasco JG. PABLO analysis of RNA: 5'-phosphorylation state and 5'-end mapping. Methods in Enzymology. 447: 83-98. PMID 19161839 DOI: 10.1016/S0076-6879(08)02205-2  0.798
2008 Richards J, Belasco JG. A new window onto translational repression by bacterial sRNAs. Molecular Cell. 32: 751-3. PMID 19111653 DOI: 10.1016/J.Molcel.2008.12.009  0.391
2008 Wu L, Fan J, Belasco JG. Importance of translation and nonnucleolytic ago proteins for on-target RNA interference. Current Biology : Cb. 18: 1327-32. PMID 18771919 DOI: 10.1016/J.Cub.2008.07.072  0.71
2008 Wu L, Belasco JG. Let me count the ways: mechanisms of gene regulation by miRNAs and siRNAs. Molecular Cell. 29: 1-7. PMID 18206964 DOI: 10.1016/J.Molcel.2007.12.010  0.622
2008 Deana A, Celesnik H, Belasco JG. The bacterial enzyme RppH triggers messenger RNA degradation by 5' pyrophosphate removal. Nature. 451: 355-8. PMID 18202662 DOI: 10.1038/Nature06475  0.846
2007 Celesnik H, Deana A, Belasco JG. Initiation of RNA decay in Escherichia coli by 5' pyrophosphate removal. Molecular Cell. 27: 79-90. PMID 17612492 DOI: 10.1016/J.Molcel.2007.05.038  0.837
2006 Wu L, Fan J, Belasco JG. MicroRNAs direct rapid deadenylation of mRNA. Proceedings of the National Academy of Sciences of the United States of America. 103: 4034-9. PMID 16495412 DOI: 10.1073/Pnas.0510928103  0.623
2005 Deana A, Belasco JG. Lost in translation: the influence of ribosomes on bacterial mRNA decay. Genes & Development. 19: 2526-33. PMID 16264189 DOI: 10.1101/Gad.1348805  0.503
2005 Wu L, Belasco JG. Micro-RNA regulation of the mammalian lin-28 gene during neuronal differentiation of embryonal carcinoma cells. Molecular and Cellular Biology. 25: 9198-208. PMID 16227573 DOI: 10.1128/Mcb.25.21.9198-9208.2005  0.619
2004 Jiang X, Belasco JG. Catalytic activation of multimeric RNase E and RNase G by 5'-monophosphorylated RNA. Proceedings of the National Academy of Sciences of the United States of America. 101: 9211-6. PMID 15197283 DOI: 10.1073/Pnas.0401382101  0.603
2004 Deana A, Belasco JG. The function of RNase G in Escherichia coli is constrained by its amino and carboxyl termini. Molecular Microbiology. 51: 1205-17. PMID 14763991 DOI: 10.1046/J.1365-2958.2003.03905.X  0.514
2002 Diwa AA, Jiang X, Schapira M, Belasco JG. Two distinct regions on the surface of an RNA-binding domain are crucial for RNase E function. Molecular Microbiology. 46: 959-69. PMID 12421303 DOI: 10.1046/J.1365-2958.2002.03231.X  0.808
2002 Feldbrügge M, Arizti P, Sullivan ML, Zamore PD, Belasco JG, Green PJ. Comparative analysis of the plant mRNA-destabilizing element, DST, in mammalian and tobacco cells. Plant Molecular Biology. 49: 215-23. PMID 11999376 DOI: 10.1023/A:1014936824187  0.322
2002 Jain C, Deana A, Belasco JG. Consequences of RNase E scarcity in Escherichia coli. Molecular Microbiology. 43: 1053-64. PMID 11929550 DOI: 10.1046/J.1365-2958.2002.02808.X  0.585
2002 Diwa AA, Belasco JG. Critical features of a conserved RNA stem-loop important for feedback regulation of RNase E synthesis. The Journal of Biological Chemistry. 277: 20415-22. PMID 11919204 DOI: 10.1074/Jbc.M202313200  0.821
2001 Danner S, Belasco JG. T7 phage display: a novel genetic selection system for cloning RNA-binding proteins from cDNA libraries. Proceedings of the National Academy of Sciences of the United States of America. 98: 12954-9. PMID 11606722 DOI: 10.1073/Pnas.211439598  0.484
2001 Jain C, Belasco JG. Structural model for the cooperative assembly of HIV-1 Rev multimers on the RRE as deduced from analysis of assembly-defective mutants. Molecular Cell. 7: 603-14. PMID 11463385 DOI: 10.1016/S1097-2765(01)00207-6  0.369
2000 Jain C, Belasco JG. Rapid genetic analysis of RNA-protein interactions by translational repression in Escherichia coli. Methods in Enzymology. 318: 309-32. PMID 10889996 DOI: 10.1016/S0076-6879(00)18060-7  0.493
2000 Jiang X, Diwa A, Belasco JG. Regions of RNase E important for 5'-end-dependent RNA cleavage and autoregulated synthesis. Journal of Bacteriology. 182: 2468-75. PMID 10762247 DOI: 10.1128/Jb.182.9.2468-2475.2000  0.819
2000 Diwa A, Bricker AL, Jain C, Belasco JG. An evolutionarily conserved RNA stem-loop functions as a sensor that directs feedback regulation of RNase E gene expression. Genes & Development. 14: 1249-1260. DOI: 10.1101/Gad.14.10.1249  0.823
1999 Bricker AL, Belasco JG. Importance of a 5' stem-loop for longevity of papA mRNA in Escherichia coli. Journal of Bacteriology. 181: 3587-90. PMID 10348874 DOI: 10.1128/Jb.181.11.3587-3590.1999  0.521
1998 Rimmele ME, Belasco JG. Target discrimination by RNA-binding proteins: role of the ancillary protein U2A' and a critical leucine residue in differentiating the RNA-binding specificity of spliceosomal proteins U1A and U2B". Rna (New York, N.Y.). 4: 1386-96. PMID 9814759 DOI: 10.1017/S1355838298981171  0.434
1998 Laird-Offringa IA, Belasco JG. RNA-binding proteins tamed Nature Structural Biology. 5: 665-668. PMID 9699622 DOI: 10.1038/1356  0.435
1997 Bouvet P, Jain C, Belasco JG, Amalric F, Erard M. RNA recognition by the joint action of two nucleolin RNA-binding domains: Genetic analysis and structural modeling Embo Journal. 16: 5235-5246. PMID 9311984 DOI: 10.1093/Emboj/16.17.5235  0.487
1996 Jain C, Belasco JG. A structural model for the HIV-1 Rev-RRE complex deduced from altered-specificity rev variants isolated by a rapid genetic strategy. Cell. 87: 115-25. PMID 8858154 DOI: 10.1016/S0092-8674(00)81328-8  0.451
1996 Aristarkhov A, Mikulskis A, Belasco JG, Lin EC. Translation of the adhE transcript to produce ethanol dehydrogenase requires RNase III cleavage in Escherichia coli. Journal of Bacteriology. 178: 4327-32. PMID 8763968 DOI: 10.1128/Jb.178.14.4327-4332.1996  0.427
1996 Laird-Offringa IA, Belasco JG. In vitro genetic analysis of RNA-binding proteins using phage display libraries Methods in Enzymology. 267: 149-168. PMID 8743315 DOI: 10.1016/S0076-6879(96)67011-6  0.496
1995 Laird-Offringa IA, Belasco JG. Analysis of RNA-binding proteins by in vitro genetic selection: Identification of an amino acid residue important for locking U1A onto its RNA target Proceedings of the National Academy of Sciences of the United States of America. 92: 11859-11863. PMID 8524863 DOI: 10.1073/Pnas.92.25.11859  0.487
1995 Zubiaga AM, Belasco JG, Greenberg ME. The nonamer UUAUUUAUU is the key AU-rich sequence motif that mediates mRNA degradation. Molecular and Cellular Biology. 15: 2219-30. PMID 7891716 DOI: 10.1128/Mcb.15.4.2219  0.458
1995 Jain C, Belasco JG. RNase E autoregulates its synthesis by controlling the degradation rate of its own mRNA in Escherichia coli: unusual sensitivity of the rne transcript to RNase E activity. Genes & Development. 9: 84-96. PMID 7530223 DOI: 10.1101/Gad.9.1.84  0.586
1994 Hansen MJ, Chen LH, Fejzo ML, Belasco JG. The ompA 5' untranslated region impedes a major pathway for mRNA degradation in Escherichia coli. Molecular Microbiology. 12: 707-16. PMID 8052123 DOI: 10.1111/J.1365-2958.1994.Tb01058.X  0.493
1993 Wellington CL, Greenberg ME, Belasco JG. The destabilizing elements in the coding region of c-fos mRNA are recognized as RNA. Molecular and Cellular Biology. 13: 5034-42. PMID 8336733 DOI: 10.1128/Mcb.13.8.5034  0.465
1992 Schiavi SC, Belasco JG, Greenberg ME. Regulation of proto-oncogene mRNA stability. Biochimica Et Biophysica Acta. 1114: 95-106. PMID 1457466 DOI: 10.1016/0304-419X(92)90009-N  0.325
1992 Emory SA, Bouvet P, Belasco JG. A 5'-terminal stem-loop structure can stabilize mRNA in Escherichia coli. Genes & Development. 6: 135-48. PMID 1370426 DOI: 10.1101/Gad.6.1.135  0.601
1992 Bouvet P, Belasco JG. Control of RNase E-mediated RNA degradation by 5'-terminal base pairing in E. coli. Nature. 360: 488-91. PMID 1280335 DOI: 10.1038/360488A0  0.641
1992 Wellington CL, Belasco JG. Autoregulation through translation Current Biology. 2: 216-218. DOI: 10.1016/0960-9822(92)90544-K  0.388
1991 Shyu AB, Belasco JG, Greenberg ME. Two distinct destabilizing elements in the c-fos message trigger deadenylation as a first step in rapid mRNA decay. Genes & Development. 5: 221-31. PMID 1899842 DOI: 10.1101/Gad.5.2.221  0.397
1991 Chen LH, Emory SA, Bricker AL, Bouvet P, Belasco JG. Structure and function of a bacterial mRNA stabilizer: analysis of the 5' untranslated region of ompA mRNA. Journal of Bacteriology. 173: 4578-86. PMID 1713205 DOI: 10.1128/Jb.173.15.4578-4586.1991  0.524
1990 Chen CY, Belasco JG. Degradation of pufLMX mRNA in Rhodobacter capsulatus is initiated by nonrandom endonucleolytic cleavage. Journal of Bacteriology. 172: 4578-86. PMID 2165480 DOI: 10.1128/Jb.172.8.4578-4586.1990  0.531
1990 Emory SA, Belasco JG. The ompA 5' untranslated RNA segment functions in Escherichia coli as a growth-rate-regulated mRNA stabilizer whose activity is unrelated to translational efficiency. Journal of Bacteriology. 172: 4472-81. PMID 1695894 DOI: 10.1128/Jb.172.8.4472-4481.1990  0.548
1989 Belasco JG, Chen CY. Mechanism of puf mRNA degradation: the role of an intercistronic stem-loop structure. Gene. 72: 109-17. PMID 3243429 DOI: 10.1016/0378-1119(88)90132-1  0.493
1989 Belasco JG, Higgins CF. Mechanisms of mRNA decay in bacteria: a perspective. Gene. 72: 15-23. PMID 3072246 DOI: 10.1016/0378-1119(88)90123-0  0.571
1989 Shyu AB, Greenberg ME, Belasco JG. The c-fos transcript is targeted for rapid decay by two distinct mRNA degradation pathways. Genes & Development. 3: 60-72. PMID 2496006 DOI: 10.1101/Gad.3.1.60  0.418
1988 Chen CY, Beatty JT, Cohen SN, Belasco JG. An intercistronic stem-loop structure functions as an mRNA decay terminator necessary but insufficient for puf mRNA stability. Cell. 52: 609-19. PMID 2449287 DOI: 10.1016/0092-8674(88)90473-4  0.514
1987 Nilsson G, Belasco JG, Cohen SN, von Gabain A. Effect of premature termination of translation on mRNA stability depends on the site of ribosome release. Proceedings of the National Academy of Sciences of the United States of America. 84: 4890-4. PMID 2440033 DOI: 10.1073/Pnas.84.14.4890  0.455
1987 Klug G, Adams CW, Belasco J, Doerge B, Cohen SN. Biological consequences of segmental alterations in mRNA stability: effects of deletion of the intercistronic hairpin loop region of the Rhodobacter capsulatus puf operon. The Embo Journal. 6: 3515-3520. DOI: 10.1002/J.1460-2075.1987.Tb02677.X  0.454
1986 Belasco JG, Nilsson G, von Gabain A, Cohen SN. The stability of E. coli gene transcripts is dependent on determinants localized to specific mRNA segments. Cell. 46: 245-51. PMID 3521892 DOI: 10.1016/0092-8674(86)90741-5  0.484
1985 Belasco JG, Beatty JT, Adams CW, von Gabain A, Cohen SN. Differential expression of photosynthesis genes in R. capsulata results from segmental differences in stability within the polycistronic rxcA transcript. Cell. 40: 171-81. PMID 2981627 DOI: 10.1016/0092-8674(85)90320-4  0.45
1984 Nilsson G, Belasco JG, Cohen SN, von Gabain A. Growth-rate dependent regulation of mRNA stability in Escherichia coli. Nature. 312: 75-7. PMID 6387508 DOI: 10.1038/312075A0  0.411
1983 von Gabain A, Belasco JG, Schottel JL, Chang AC, Cohen SN. Decay of mRNA in Escherichia coli: Investigation of the fate of specific segments of transcripts Proceedings of the National Academy of Sciences of the United States of America. 80: 653-657. PMID 6187001 DOI: 10.1073/Pnas.80.3.653  0.52
1980 Fisher J, Belasco JG, Charnas RL, Khosla S, Knowles JR. Beta-lactamase inactivation by mechanism-based reagents. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 289: 309-19. PMID 6109326 DOI: 10.1098/Rstb.1980.0048  0.321
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