| Year |
Citation |
Score |
| 2020 |
Reinders J, Altenbuchinger M, Limm K, Schwarzfischer P, Scheidt T, Strasser L, Richter J, Szczepanowski M, Huber CG, Klapper W, Spang R, Oefner PJ. Platform independent protein-based cell-of-origin subtyping of diffuse large B-cell lymphoma in formalin-fixed paraffin-embedded tissue. Scientific Reports. 10: 7876. PMID 32398793 DOI: 10.1038/S41598-020-64212-Z |
0.366 |
|
| 2020 |
Minderjahn J, Schmidt A, Fuchs A, Schill R, Raithel J, Babina M, Schmidl C, Gebhard C, Schmidhofer S, Mendes K, Ratermann A, Glatz D, Nützel M, Edinger M, Hoffman P, ... Spang R, et al. Mechanisms governing the pioneering and redistribution capabilities of the non-classical pioneer PU.1. Nature Communications. 11: 402. PMID 31964861 DOI: 10.1038/S41467-019-13960-2 |
0.327 |
|
| 2019 |
Arlt A, von Bonin F, Rehberg T, Perez-Rubio P, Engelmann JC, Limm K, Reinke S, Dullin C, Sun X, Specht R, Maulhardt M, Linke F, Bunt G, Klapper W, Vockerodt M, ... ... Spang R, et al. High CD206 levels in Hodgkin lymphoma-educated macrophages are linked to matrix-remodeling and lymphoma dissemination. Molecular Oncology. PMID 31825135 DOI: 10.1002/1878-0261.12616 |
0.336 |
|
| 2019 |
Staiger AM, Altenbuchinger M, Ziepert M, Kohler C, Horn H, Huttner M, Hüttl KS, Glehr G, Klapper W, Szczepanowski M, Richter J, Stein H, Feller AC, Möller P, Hansmann ML, ... ... Spang R, et al. A novel lymphoma-associated macrophage interaction signature (LAMIS) provides robust risk prognostication in diffuse large B-cell lymphoma clinical trial cohorts of the DSHNHL. Leukemia. PMID 31530861 DOI: 10.1038/S41375-019-0573-Y |
0.359 |
|
| 2019 |
Wagner M, Hänsel R, Reinke S, Richter J, Altenbuchinger M, Braumann UD, Spang R, Löffler M, Klapper W. Automated macrophage counting in DLBCL tissue samples: a ROF filter based approach. Biological Procedures Online. 21: 13. PMID 31303867 DOI: 10.1186/S12575-019-0098-9 |
0.323 |
|
| 2019 |
Itzel T, Spang R, Maass T, Munker S, Roessler S, Ebert MP, Schlitt HJ, Herr W, Evert M, Teufel A. Random gene sets in predicting survival of patients with hepatocellular carcinoma. Journal of Molecular Medicine. 97: 879-888. PMID 31001651 DOI: 10.1007/S00109-019-01764-2 |
0.361 |
|
| 2019 |
Kleo K, Dimitrova L, Oker E, Tomaszewski N, Berg E, Taruttis F, Engelmann JC, Schwarzfischer P, Reinders J, Spang R, Gronwald W, Oefner PJ, Hummel M. Identification of ADGRE5 as discriminating MYC target between Burkitt lymphoma and diffuse large B-cell lymphoma Bmc Cancer. 19: 322. PMID 30953469 DOI: 10.1186/S12885-019-5537-0 |
0.436 |
|
| 2019 |
Schnitter A, Kohler CW, Reddemann K, Reinke S, Thorns C, Fend F, Federmann B, Möller P, Szczepanowski M, Spang R, Klapper W. Therapeutic targets and microenvironment in sequential biopsies of classical Hodgkin lymphoma at diagnosis and relapse Journal of Hematopathology. 12: 11-17. DOI: 10.1007/S12308-019-00350-2 |
0.329 |
|
| 2018 |
Reinke S, Richter J, Fend F, Feller A, Hansmann ML, Hüttl K, Oschlies I, Ott G, Möller P, Rosenwald A, Stein H, Altenbuchinger M, Spang R, Klapper W. Round-robin test for the cell-of-origin classification of diffuse large B-cell lymphoma-a feasibility study using full slide staining. Virchows Archiv : An International Journal of Pathology. PMID 29730836 DOI: 10.1007/S00428-018-2367-4 |
0.389 |
|
| 2018 |
Feist M, Schwarzfischer P, Heinrich P, Sun X, Kemper J, von Bonin F, Perez-Rubio P, Taruttis F, Rehberg T, Dettmer K, Gronwald W, Reinders J, Engelmann JC, Dudek J, Klapper W, ... ... Spang R, et al. Cooperative STAT/NF-κB signaling regulates lymphoma metabolic reprogramming and aberrant GOT2 expression. Nature Communications. 9: 1514. PMID 29666362 DOI: 10.1038/S41467-018-03803-X |
0.343 |
|
| 2018 |
Horn H, Kohler C, Witzig R, Kreuz M, Leich E, Klapper W, Hummel M, Loeffler M, Trümper L, Spang R, Rosenwald A, Ott G. Gene expression profiling reveals a close relationship between follicular lymphoma grade 3A and 3B, but distinct profiles of follicular lymphoma grade 1 and 2. Haematologica. PMID 29567771 DOI: 10.3324/Haematol.2017.181024 |
0.41 |
|
| 2018 |
Staiger AM, Altenbuchinger M, Ziepert M, Kohler C, Horn H, Huttner M, Huettl K, Klapper W, Szczepanowski M, Richter J, Rosenwald A, Stein H, Feller A, Moeller P, Hansmann M, ... ... Spang R, et al. A New Stromal Signature Applicable to Formalin-Fixed Paraffin-Embedded Tissues Identifies Patients at Risk in Prospective Clinical Trials of the German High-Grade Non-Hodgkin Lymphoma Study Group Blood. 132: 343-343. DOI: 10.1182/Blood-2018-99-112450 |
0.388 |
|
| 2017 |
Paul U, Richter J, Stuhlmann-Laiesz C, Kreuz M, Nagel I, Horn H, Staiger AM, Aukema SM, Hummel M, Ott G, Spang R, Rosenwald A, Feller AC, Cogliatti S, Stein H, et al. Advanced patient age at diagnosis of diffuse large B-cell lymphoma is associated with molecular characteristics including ABC-subtype and high expression of MYC. Leukemia & Lymphoma. 1-9. PMID 28838257 DOI: 10.1080/10428194.2017.1365851 |
0.336 |
|
| 2017 |
Oschlies I, Kohler CW, Szczepanowski M, Koch K, Gontarewicz A, Metze D, Hillen U, Richter J, Spang R, Klapper W. Spindle-cell variant of primary cutaneous follicle center B-cell lymphomas are germinal center B-cell lymphomas by gene expression profiling using formalin-fixed paraffin embedded specimen. The Journal of Investigative Dermatology. PMID 28684330 DOI: 10.1016/J.Jid.2017.06.016 |
0.393 |
|
| 2017 |
Szczepanowski M, Lange J, Kohler CW, Masque-Soler N, Zimmermann M, Aukema SM, Altenbuchinger M, Rehberg T, Mahn F, Siebert R, Spang R, Burkhardt B, Klapper W. Cell-of-origin classification by gene expression and MYC-rearrangements in diffuse large B-cell lymphoma of children and adolescents. British Journal of Haematology. PMID 28643426 DOI: 10.1111/Bjh.14812 |
0.394 |
|
| 2017 |
Taruttis F, Feist M, Schwarzfischer P, Gronwald W, Kube D, Spang R, Engelmann JC. External calibration with Drosophila whole-cell spike-ins delivers absolute mRNA fold changes from human RNA-Seq and qPCR data Biotechniques. 62: 53-61. PMID 28193148 DOI: 10.2144/000114514 |
0.403 |
|
| 2017 |
Schwarzfischer P, Reinders J, Dettmer K, Kleo K, Dimitrova L, Hummel M, Feist M, Kube D, Szczepanowski M, Klapper W, Taruttis F, Engelmann JC, Spang R, Gronwald W, Oefner PJ. Comprehensive Metaboproteomics of Burkitt's and Diffuse Large B-Cell Lymphoma Cell Lines and Primary Tumor Tissues Reveals Distinct Differences in Pyruvate Content and Metabolism. Journal of Proteome Research. 16: 1105-1120. PMID 28161958 DOI: 10.1021/Acs.Jproteome.6B00164 |
0.353 |
|
| 2017 |
Lottaz C, Gronwald W, Spang R, Engelmann JC. High-Dimensional Profiling for Computational Diagnosis. Methods of Molecular Biology. 1526: 205-229. PMID 27896744 DOI: 10.1007/978-1-4939-6613-4_12 |
0.334 |
|
| 2017 |
Feist M, Kemper J, Taruttis F, Rehberg T, Engelmann JC, Gronwald W, Hummel M, Spang R, Kube D. Synergy of interleukin 10 and toll-like receptor 9 signalling in B cell proliferation: Implications for lymphoma pathogenesis. International Journal of Cancer. 140: 1147-1158. PMID 27668411 DOI: 10.1002/Ijc.30444 |
0.348 |
|
| 2017 |
Altenbuchinger M, Rehberg T, Zacharias H, Stämmler F, Dettmer K, Weber D, Hiergeist A, Gessner A, Holler E, Oefner PJ, Spang R. Reference point insensitive molecular data analysis. Bioinformatics. 33: 219-226. PMID 27634945 DOI: 10.1093/Bioinformatics/Btw598 |
0.302 |
|
| 2016 |
Hosseini H, Obradović MM, Hoffmann M, Harper KL, Sosa MS, Werner-Klein M, Nanduri LK, Werno C, Ehrl C, Maneck M, Patwary N, Haunschild G, Gužvić M, Reimelt C, Grauvogl M, ... ... Spang R, et al. Early dissemination seeds metastasis in breast cancer. Nature. PMID 27974799 DOI: 10.1038/Nature20785 |
0.302 |
|
| 2016 |
Moffa G, Erdmann G, Voloshanenko O, Hundsrucker C, Sadeh MJ, Boutros M, Spang R. Refining Pathways: A Model Comparison Approach. Plos One. 11: e0155999. PMID 27248690 DOI: 10.1371/Journal.Pone.0155999 |
0.32 |
|
| 2016 |
Schrader A, Meyer K, Walther N, Stolz A, Feist M, Hand E, von Bonin F, Ever M, Kohler C, Shirneshan K, Vockerodt M, Klapper W, Szczepanowski M, Murray PG, Bastians H, ... ... Spang R, et al. Identification of a new gene regulatory circuit involving B cell receptor activated signaling using a combined analysis of experimental, clinical and global gene expression data. Oncotarget. PMID 27166259 DOI: 10.18632/Oncotarget.9219 |
0.444 |
|
| 2016 |
Moeckel S, Vollmann-Zwerenz A, Proescholdt M, Brawanski A, Riemenschneider MJ, Bogdahn U, Bosserhoff A, Spang R, Hau P. Validation Study: Response-Predictive Gene Expression Profiling of Glioma Progenitor Cells In Vitro. Plos One. 11. PMID 26978262 DOI: 10.1371/Journal.Pone.0151312 |
0.378 |
|
| 2015 |
Taruttis F, Spang R, Engelmann JC. A statistical approach to virtual cellular experiments: improved causal discovery using accumulation IDA (aIDA). Bioinformatics (Oxford, England). PMID 26249813 DOI: 10.1093/Bioinformatics/Btv461 |
0.366 |
|
| 2015 |
Masqué-Soler N, Szczepanowski M, Kohler CW, Aukema SM, Nagel I, Richter J, Siebert R, Spang R, Burkhardt B, Klapper W. Clinical and pathological features of Burkitt lymphoma showing expression of BCL2 - an analysis including gene expression in formalin-fixed paraffin-embedded tissue. British Journal of Haematology. PMID 26218299 DOI: 10.1111/Bjh.13624 |
0.389 |
|
| 2015 |
Weber D, Oefner PJ, Hiergeist A, Koestler J, Gessner A, Weber M, Hahn J, Wolff D, Stämmler F, Spang R, Herr W, Dettmer K, Holler E. Low urinary indoxyl sulfate levels early after ASCT reflect a disrupted microbiome and are associated with poor outcome. Blood. PMID 26209659 DOI: 10.1182/Blood-2015-04-638858 |
0.314 |
|
| 2015 |
Engelmann JC, Amann T, Ott-Rötzer B, Nützel M, Reinders Y, Reinders J, Thasler WE, Kristl T, Teufel A, Huber CG, Oefner PJ, Spang R, Hellerbrand C. Causal Modeling of Cancer-Stromal Communication Identifies PAPPA as a Novel Stroma-Secreted Factor Activating NFκB Signaling in Hepatocellular Carcinoma. Plos Computational Biology. 11: e1004293. PMID 26020769 DOI: 10.1371/Journal.Pcbi.1004293 |
0.344 |
|
| 2014 |
Moeckel S, Meyer K, Leukel P, Heudorfer F, Seliger C, Stangl C, Bogdahn U, Proescholdt M, Brawanski A, Vollmann-Zwerenz A, Riemenschneider MJ, Bosserhoff AK, Spang R, Hau P. Response-predictive gene expression profiling of glioma progenitor cells in vitro. Plos One. 9: e108632. PMID 25268354 DOI: 10.1371/Journal.Pone.0108632 |
0.365 |
|
| 2014 |
Hannus M, Beitzinger M, Engelmann JC, Weickert MT, Spang R, Hannus S, Meister G. siPools: highly complex but accurately defined siRNA pools eliminate off-target effects. Nucleic Acids Research. 42: 8049-61. PMID 24875475 DOI: 10.1093/Nar/Gku480 |
0.325 |
|
| 2014 |
Dorn C, Engelmann JC, Saugspier M, Koch A, Hartmann A, Müller M, Spang R, Bosserhoff A, Hellerbrand C. Increased expression of c-Jun in nonalcoholic fatty liver disease. Laboratory Investigation; a Journal of Technical Methods and Pathology. 94: 394-408. PMID 24492282 DOI: 10.1038/labinvest.2014.3 |
0.318 |
|
| 2014 |
Salaverria I, Martin-Guerrero I, Wagener R, Kreuz M, Kohler CW, Richter J, Pienkowska-Grela B, Adam P, Burkhardt B, Claviez A, Damm-Welk C, Drexler HG, Hummel M, Jaffe ES, Küppers R, ... ... Spang R, et al. A recurrent 11q aberration pattern characterizes a subset of MYC-negative high-grade B-cell lymphomas resembling Burkitt lymphoma. Blood. 123: 1187-98. PMID 24398325 DOI: 10.1182/Blood-2013-06-507996 |
0.331 |
|
| 2014 |
Dümcke S, Bräuer J, Anchang B, Spang R, Beerenwinkel N, Tresch A. Exact likelihood computation in Boolean networks with probabilistic time delays, and its application in signal network reconstruction. Bioinformatics (Oxford, England). 30: 414-9. PMID 24292937 DOI: 10.1093/Bioinformatics/Btt696 |
0.322 |
|
| 2014 |
Aukema SM, Kreuz M, Kohler CW, Rosolowski M, Hasenclever D, Hummel M, Küppers R, Lenze D, Ott G, Pott C, Richter J, Rosenwald A, Szczepanowski M, Schwaenen C, Stein H, ... ... Spang R, et al. Biological characterization of adult MYC-translocation-positive mature B-cell lymphomas other than molecular Burkitt lymphoma. Haematologica. 99: 726-35. PMID 24179151 DOI: 10.3324/Haematol.2013.091827 |
0.421 |
|
| 2013 |
Masqué-Soler N, Szczepanowski M, Kohler CW, Spang R, Klapper W. Molecular classification of mature aggressive B-cell lymphoma using digital multiplexed gene expression on formalin-fixed paraffin-embedded biopsy specimens. Blood. 122: 1985-6. PMID 24030260 DOI: 10.1182/Blood-2013-06-508937 |
0.385 |
|
| 2013 |
Burghardt T, Kastner J, Suleiman H, Rivera-Milla E, Stepanova N, Lottaz C, Kubitza M, Böger CA, Schmidt S, Gorski M, de Vries U, Schmidt H, Hertting I, Kopp J, Rascle A, ... ... Spang R, et al. LMX1B is essential for the maintenance of differentiated podocytes in adult kidneys. Journal of the American Society of Nephrology : Jasn. 24: 1830-48. PMID 23990680 DOI: 10.1681/Asn.2012080788 |
0.31 |
|
| 2013 |
Schmid R, Meyer K, Spang R, Schittek B, Bosserhoff AK. Melanoma inhibitory activity promotes melanoma development through activation of YBX1. Pigment Cell & Melanoma Research. 26: 685-96. PMID 23672612 DOI: 10.1111/Pcmr.12119 |
0.316 |
|
| 2013 |
Walther N, Ulrich A, Vockerodt M, von Bonin F, Klapper W, Meyer K, Eberth S, Pukrop T, Spang R, Trümper L, Kube D. Aberrant lymphocyte enhancer-binding factor 1 expression is characteristic for sporadic Burkitt's lymphoma. The American Journal of Pathology. 182: 1092-8. PMID 23375451 DOI: 10.1016/J.Ajpath.2012.12.013 |
0.455 |
|
| 2013 |
Schif B, Lennerz JK, Kohler CW, Bentink S, Kreuz M, Melzner I, Ritz O, Trümper L, Loeffler M, Spang R, Möller P. SOCS1 mutation subtypes predict divergent outcomes in diffuse large B-Cell lymphoma (DLBCL) patients. Oncotarget. 4: 35-47. PMID 23296022 DOI: 10.18632/Oncotarget.774 |
0.339 |
|
| 2013 |
Kelly GL, Stylianou J, Rasaiyaah J, Wei W, Thomas W, Croom-Carter D, Kohler C, Spang R, Woodman C, Kellam P, Rickinson AB, Bell AI. Different patterns of Epstein-Barr virus latency in endemic Burkitt lymphoma (BL) lead to distinct variants within the BL-associated gene expression signature. Journal of Virology. 87: 2882-94. PMID 23269792 DOI: 10.1128/Jvi.03003-12 |
0.391 |
|
| 2012 |
Richter J, Schlesner M, Hoffmann S, Kreuz M, Leich E, Burkhardt B, Rosolowski M, Ammerpohl O, Wagener R, Bernhart SH, Lenze D, Szczepanowski M, Paulsen M, Lipinski S, Russell RB, ... ... Spang R, et al. Recurrent mutation of the ID3 gene in Burkitt lymphoma identified by integrated genome, exome and transcriptome sequencing. Nature Genetics. 44: 1316-20. PMID 23143595 DOI: 10.1038/Ng.2469 |
0.394 |
|
| 2012 |
Engelmann JC, Spang R. A least angle regression model for the prediction of canonical and non-canonical miRNA-mRNA interactions. Plos One. 7: e40634. PMID 22815777 DOI: 10.1371/Journal.Pone.0040634 |
0.301 |
|
| 2012 |
Kohl SM, Klein MS, Hochrein J, Oefner PJ, Spang R, Gronwald W. State-of-the art data normalization methods improve NMR-based metabolomic analysis. Metabolomics : Official Journal of the Metabolomic Society. 8: 146-160. PMID 22593726 DOI: 10.1007/S11306-011-0350-Z |
0.3 |
|
| 2012 |
Klapper W, Kreuz M, Kohler CW, Burkhardt B, Szczepanowski M, Salaverria I, Hummel M, Loeffler M, Pellissery S, Woessmann W, Schwänen C, Trümper L, Wessendorf S, Spang R, Hasenclever D, et al. Patient age at diagnosis is associated with the molecular characteristics of diffuse large B-cell lymphoma. Blood. 119: 1882-7. PMID 22238326 DOI: 10.1182/Blood-2011-10-388470 |
0.341 |
|
| 2012 |
Schrader A, Bentink S, Spang R, Lenze D, Hummel M, Kuo M, Arrand JR, Murray PG, Trümper L, Kube D, Vockerodt M. High Myc activity is an independent negative prognostic factor for diffuse large B cell lymphomas. International Journal of Cancer. Journal International Du Cancer. 131: E348-61. PMID 21913186 DOI: 10.1002/Ijc.26423 |
0.395 |
|
| 2012 |
Lennerz JK, Schif B, Kohler CW, Bentink S, Kreuz M, Melzner I, Trümper L, Löffler M, Spang R, Moeller P. SOCS1 Mutation Subtypes Predict Divergent Outcomes in DLBCL Patients Blood. 120: 419-419. DOI: 10.1182/Blood.V120.21.419.419 |
0.335 |
|
| 2011 |
Seitz V, Butzhammer P, Hirsch B, Hecht J, Gütgemann I, Ehlers A, Lenze D, Oker E, Sommerfeld A, von der Wall E, König C, Zinser C, Spang R, Hummel M. Deep sequencing of MYC DNA-binding sites in Burkitt lymphoma. Plos One. 6: e26837. PMID 22102868 DOI: 10.1371/Journal.Pone.0026837 |
0.393 |
|
| 2011 |
Maneck M, Schrader A, Kube D, Spang R. Genomic data integration using guided clustering. Bioinformatics (Oxford, England). 27: 2231-8. PMID 21685050 DOI: 10.1093/Bioinformatics/Btr363 |
0.314 |
|
| 2011 |
Salaverria I, Philipp C, Oschlies I, Kohler CW, Kreuz M, Szczepanowski M, Burkhardt B, Trautmann H, Gesk S, Andrusiewicz M, Berger H, Fey M, Harder L, Hasenclever D, Hummel M, ... ... Spang R, et al. Translocations activating IRF4 identify a subtype of germinal center-derived B-cell lymphoma affecting predominantly children and young adults. Blood. 118: 139-47. PMID 21487109 DOI: 10.1182/Blood-2011-01-330795 |
0.388 |
|
| 2010 |
Scholtysik R, Kreuz M, Klapper W, Burkhardt B, Feller AC, Hummel M, Loeffler M, Rosolowski M, Schwaenen C, Spang R, Stein H, Thorns C, Trümper L, Vater I, Wessendorf S, et al. Detection of genomic aberrations in molecularly defined Burkitt's lymphoma by array-based, high resolution, single nucleotide polymorphism analysis. Haematologica. 95: 2047-55. PMID 20823134 DOI: 10.3324/Haematol.2010.026831 |
0.407 |
|
| 2010 |
Lottaz C, Beier D, Meyer K, Kumar P, Hermann A, Schwarz J, Junker M, Oefner PJ, Bogdahn U, Wischhusen J, Spang R, Storch A, Beier CP. Transcriptional profiles of CD133+ and CD133- glioblastoma-derived cancer stem cell lines suggest different cells of origin. Cancer Research. 70: 2030-40. PMID 20145155 DOI: 10.1158/0008-5472.Can-09-1707 |
0.349 |
|
| 2010 |
Schrader A, Bentink S, Spang R, Lenze D, Hummel M, Kuo M, Murray P, Trümper L, Kube D, Vockerodt M. 417 A c-Myc induced gene expression signature in human germinal center B cells predicts subtypes of aggressive non-Hodgkin Lymphoma Ejc Supplements. 8: 107. DOI: 10.1016/S1359-6349(10)71218-0 |
0.396 |
|
| 2009 |
Anchang B, Sadeh MJ, Jacob J, Tresch A, Vlad MO, Oefner PJ, Spang R. Modeling the temporal interplay of molecular signaling and gene expression by using dynamic nested effects models. Proceedings of the National Academy of Sciences of the United States of America. 106: 6447-52. PMID 19329492 DOI: 10.7490/F1000Research.271.1 |
0.317 |
|
| 2009 |
Martín-Subero JI, Kreuz M, Bibikova M, Bentink S, Ammerpohl O, Wickham-Garcia E, Rosolowski M, Richter J, Lopez-Serra L, Ballestar E, Berger H, Agirre X, Bernd HW, Calvanese V, Cogliatti SB, ... ... Spang R, et al. New insights into the biology and origin of mature aggressive B-cell lymphomas by combined epigenomic, genomic, and transcriptional profiling. Blood. 113: 2488-97. PMID 19075189 DOI: 10.1182/Blood-2008-04-152900 |
0.398 |
|
| 2009 |
Schwaenen C, Viardot A, Berger H, Barth TF, Bentink S, Döhner H, Enz M, Feller AC, Hansmann ML, Hummel M, Kestler HA, Klapper W, Kreuz M, Lenze D, Loeffler M, ... ... Spang R, et al. Microarray-based genomic profiling reveals novel genomic aberrations in follicular lymphoma which associate with patient survival and gene expression status. Genes, Chromosomes & Cancer. 48: 39-54. PMID 18828156 DOI: 10.1002/Gcc.20617 |
0.377 |
|
| 2009 |
Kube D, Matulewicz K, Schrader A, Bentink S, Spang R, Murray P, Trümper L, Vockerodt M. Dissecting the molecular pathogenisis of Burkitt lymphoma Cell Communication and Signaling. 7: 1-1. DOI: 10.1186/1478-811X-7-S1-A33 |
0.448 |
|
| 2008 |
Fröhlich H, Beissbarth T, Tresch A, Kostka D, Jacob J, Spang R, Markowetz F. Analyzing gene perturbation screens with nested effects models in R and bioconductor. Bioinformatics (Oxford, England). 24: 2549-50. PMID 18718939 DOI: 10.1093/Bioinformatics/Btn446 |
0.35 |
|
| 2008 |
Lottaz C, Kostka D, Markowetz F, Spang R. Computational diagnostics with gene expression profiles. Methods in Molecular Biology (Clifton, N.J.). 453: 281-96. PMID 18712310 DOI: 10.1007/978-1-60327-429-6_15 |
0.371 |
|
| 2008 |
Bentink S, Wessendorf S, Schwaenen C, Rosolowski M, Klapper W, Rosenwald A, Ott G, Banham AH, Berger H, Feller AC, Hansmann ML, Hasenclever D, Hummel M, Lenze D, Möller P, ... ... Spang R, et al. Pathway activation patterns in diffuse large B-cell lymphomas. Leukemia. 22: 1746-54. PMID 18580954 DOI: 10.1038/Leu.2008.166 |
0.401 |
|
| 2008 |
Klapper W, Szczepanowski M, Burkhardt B, Berger H, Rosolowski M, Bentink S, Schwaenen C, Wessendorf S, Spang R, Möller P, Hansmann ML, Bernd HW, Ott G, Hummel M, Stein H, et al. Molecular profiling of pediatric mature B-cell lymphoma treated in population-based prospective clinical trials. Blood. 112: 1374-81. PMID 18509088 DOI: 10.1182/Blood-2008-01-136465 |
0.374 |
|
| 2008 |
Dierlamm J, Murga Penas EM, Bentink S, Wessendorf S, Berger H, Hummel M, Klapper W, Lenze D, Rosenwald A, Haralambieva E, Ott G, Cogliatti SB, Möller P, Schwaenen C, Stein H, ... ... Spang R, et al. Gain of chromosome region 18q21 including the MALT1 gene is associated with the activated B-cell-like gene expression subtype and increased BCL2 gene dosage and protein expression in diffuse large B-cell lymphoma. Haematologica. 93: 688-96. PMID 18367485 DOI: 10.3324/Haematol.12057 |
0.42 |
|
| 2008 |
Kostka D, Spang R. Microarray based diagnosis profits from better documentation of gene expression signatures. Plos Computational Biology. 4: e22. PMID 18282081 DOI: 10.1371/Journal.Pcbi.0040022 |
0.389 |
|
| 2008 |
Montesinos-Rongen M, Brunn A, Bentink S, Basso K, Lim WK, Klapper W, Schaller C, Reifenberger G, Rubenstein J, Wiestler OD, Spang R, Dalla-Favera R, Siebert R, Deckert M. Gene expression profiling suggests primary central nervous system lymphomas to be derived from a late germinal center B cell. Leukemia. 22: 400-5. PMID 17989719 DOI: 10.1038/Sj.Leu.2405019 |
0.43 |
|
| 2007 |
Roesch A, Becker B, Bentink S, Spang R, Vogl A, Hagen I, Landthaler M, Vogt T. Ataxia telangiectasia-mutated gene is a possible biomarker for discrimination of infiltrative deep penetrating nevi and metastatic vertical growth phase melanoma. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 16: 2486-90. PMID 18006941 DOI: 10.1158/1055-9965.Epi-07-0224 |
0.402 |
|
| 2007 |
Scheid S, Spang R. Compensating for unknown confounders in microarray data analysis using filtered permutations. Journal of Computational Biology : a Journal of Computational Molecular Cell Biology. 14: 669-81. PMID 17683267 DOI: 10.1089/Cmb.2007.R009 |
0.322 |
|
| 2007 |
Lottaz C, Toedling J, Spang R. Annotation-based distance measures for patient subgroup discovery in clinical microarray studies. Bioinformatics (Oxford, England). 23: 2256-64. PMID 17586546 DOI: 10.1093/Bioinformatics/Btm322 |
0.335 |
|
| 2007 |
Rhein P, Scheid S, Ratei R, Hagemeier C, Seeger K, Kirschner-Schwabe R, Moericke A, Schrappe M, Spang R, Ludwig WD, Karawajew L. Gene expression shift towards normal B cells, decreased proliferative capacity and distinct surface receptors characterize leukemic blasts persisting during induction therapy in childhood acute lymphoblastic leukemia. Leukemia. 21: 897-905. PMID 17330098 DOI: 10.1038/Sj.Leu.2404613 |
0.383 |
|
| 2007 |
Jaeger J, Koczan D, Thiesen HJ, Ibrahim SM, Gross G, Spang R, Kunz M. Gene expression signatures for tumor progression, tumor subtype, and tumor thickness in laser-microdissected melanoma tissues. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 806-15. PMID 17289871 DOI: 10.1158/1078-0432.Ccr-06-1820 |
0.4 |
|
| 2006 |
Yang X, Bentink S, Scheid S, Spang R. Similarities of ordered gene lists. Journal of Bioinformatics and Computational Biology. 4: 693-708. PMID 16960970 DOI: 10.1142/S0219720006002120 |
0.4 |
|
| 2006 |
Jaeger J, Spang R. Selecting normalization genes for small diagnostic microarrays. Bmc Bioinformatics. 7: 388. PMID 16925821 DOI: 10.1186/1471-2105-7-388 |
0.373 |
|
| 2006 |
Kirschner-Schwabe R, Lottaz C, Tödling J, Rhein P, Karawajew L, Eckert C, von Stackelberg A, Ungethüm U, Kostka D, Kulozik AE, Ludwig WD, Henze G, Spang R, Hagemeier C, Seeger K. Expression of late cell cycle genes and an increased proliferative capacity characterize very early relapse of childhood acute lymphoblastic leukemia. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 4553-61. PMID 16899601 DOI: 10.1158/1078-0432.Ccr-06-0235 |
0.43 |
|
| 2006 |
Lottaz C, Yang X, Scheid S, Spang R. OrderedList--a bioconductor package for detecting similarity in ordered gene lists. Bioinformatics (Oxford, England). 22: 2315-6. PMID 16844712 DOI: 10.1093/Bioinformatics/Btl385 |
0.375 |
|
| 2006 |
Hummel M, Bentink S, Berger H, Klapper W, Wessendorf S, Barth TF, Bernd HW, Cogliatti SB, Dierlamm J, Feller AC, Hansmann ML, Haralambieva E, Harder L, Hasenclever D, Kühn M, ... ... Spang R, et al. A biologic definition of Burkitt's lymphoma from transcriptional and genomic profiling. The New England Journal of Medicine. 354: 2419-30. PMID 16760442 DOI: 10.1056/Nejmoa055351 |
0.385 |
|
| 2006 |
Toedling J, Rhein P, Ratei R, Karawajew L, Spang R. Automated in-silico detection of cell populations in flow cytometry readouts and its application to leukemia disease monitoring. Bmc Bioinformatics. 7: 282. PMID 16753055 DOI: 10.1186/1471-2105-7-282 |
0.305 |
|
| 2006 |
Hasse K, Kirschner-Schwabe R, Lottaz C, Proba J, Ungetuem U, Spang R, Henze G, Seeger K. TEL/AML1 Expression in a Non-B Cell Line Induces a Set of Differentially Expressed Genes, but Points to Cell Type Specific Effects of the Fusion Protein in Leukemic Blasts of TEL/AML1 Positive Patients. Blood. 108: 2221-2221. DOI: 10.1182/Blood.V108.11.2221.2221 |
0.458 |
|
| 2006 |
Rhein P, Scheid S, Ratei R, Hagemeier C, Seeger K, Kirschner-Schwabe R, Schrappe M, Spang R, Ludwig W, Karawajew L. Glucocorticoid Therapy Targets Proliferation, Differentiation and Bcl-2 Dependent Survival Signaling in ALL Blasts. Blood. 108: 1841-1841. DOI: 10.1182/Blood.V108.11.1841.1841 |
0.353 |
|
| 2005 |
Jaeger J, Weichenhan D, Ivandic B, Spang R. Early diagnostic marker panel determination for microarray based clinical studies. Statistical Applications in Genetics and Molecular Biology. 4: Article9. PMID 16646862 DOI: 10.2202/1544-6115.1109 |
0.347 |
|
| 2005 |
Markowetz F, Bloch J, Spang R. Non-transcriptional pathway features reconstructed from secondary effects of RNA interference. Bioinformatics (Oxford, England). 21: 4026-32. PMID 16159925 DOI: 10.1093/Bioinformatics/Bti662 |
0.36 |
|
| 2005 |
Yang X, Bentink S, Spang R. Detecting common gene expression patterns in multiple cancer outcome entities. Biomedical Microdevices. 7: 247-51. PMID 16133813 DOI: 10.1007/S10544-005-3032-7 |
0.312 |
|
| 2005 |
Lottaz C, Spang R. stam--a Bioconductor compliant R package for structured analysis of microarray data. Bmc Bioinformatics. 6: 211. PMID 16122395 DOI: 10.1186/1471-2105-6-211 |
0.399 |
|
| 2005 |
Scheid S, Spang R. twilight; a Bioconductor package for estimating the local false discovery rate. Bioinformatics (Oxford, England). 21: 2921-2. PMID 15817688 DOI: 10.1093/Bioinformatics/Bti436 |
0.337 |
|
| 2005 |
Lottaz C, Spang R. Molecular decomposition of complex clinical phenotypes using biologically structured analysis of microarray data. Bioinformatics (Oxford, England). 21: 1971-8. PMID 15677704 DOI: 10.1093/Bioinformatics/Bti292 |
0.378 |
|
| 2005 |
Rhein P, Scheid S, Ratei R, Hagemeier C, Seeger K, Kirschner-Schwabe R, Schrappe M, Spang R, Ludwig W, Karawajew L. Gene Expression in Leukemic Blasts Persisting at Day 8 of Induction Therapy in Childhood ALL Displays a Common Shift towards Terminally Differentiated B Cells and a Cytoreduction-Associated Impairment of the Translational Machinery. Blood. 106: 537-537. DOI: 10.1182/Blood.V106.11.537.537 |
0.41 |
|
| 2004 |
Spang R. Diagnostic signatures from microarrays: a bioinformatics concept for personalized medicine. Drug Discovery Today. 9: S32-6. PMID 23573658 DOI: 10.1016/S1478-5382(03)02329-1 |
0.391 |
|
| 2004 |
Scheid S, Spang R. A stochastic downhill search algorithm for estimating the local false discovery rate. Ieee/Acm Transactions On Computational Biology and Bioinformatics / Ieee, Acm. 1: 98-108. PMID 17048385 DOI: 10.1109/Tcbb.2004.24 |
0.35 |
|
| 2004 |
Karawajew L, Rhein P, Kostka D, Hoffmann R, Schrappe M, Spang R, Ludwig W. Molecular Targets of Glucocorticoids in Context of Apoptosis Induction in Childhood Precursor T-Cell ALL (T-ALL). Blood. 104: 988-988. DOI: 10.1182/Blood.V104.11.988.988 |
0.374 |
|
| 2004 |
Rhein P, Ratei R, Scheid S, Hagemeier C, Seeger K, Kirschner R, Schrappe M, Spang R, Ludwig W, Karawajew L. Gene Expression Analysis of Leukemic Blasts Persisting at Day 8 of Induction Therapy in Childhood ALL. Blood. 104: 522-522. DOI: 10.1182/Blood.V104.11.522.522 |
0.404 |
|
| 2004 |
Rhein P, Scheid S, Hagemeier C, Seeger K, Kirschner R, Schrappe M, Spang R, Ludwig W, Karawajew L. Differential Gene Expression in Leukemic Cells from Bone Marrow (BM) and Peripheral Blood (PB) of Pediatric Patients with Acute Lymphoblastic Leukemia (ALL). Blood. 104: 1889-1889. DOI: 10.1182/Blood.V104.11.1889.1889 |
0.417 |
|
| 2003 |
Grzeskowiak R, Witt H, Drungowski M, Thermann R, Hennig S, Perrot A, Osterziel KJ, Klingbiel D, Scheid S, Spang R, Lehrach H, Ruiz P. Expression profiling of human idiopathic dilated cardiomyopathy. Cardiovascular Research. 59: 400-11. PMID 12909323 DOI: 10.1016/S0008-6363(03)00426-7 |
0.399 |
|
| 2003 |
Blaxall BC, Spang R, Rockman HA, Koch WJ. Differential myocardial gene expression in the development and rescue of murine heart failure. Physiological Genomics. 15: 105-14. PMID 12865503 DOI: 10.1152/Physiolgenomics.00087.2003 |
0.353 |
|
| 2001 |
West M, Blanchette C, Dressman H, Huang E, Ishida S, Spang R, Zuzan H, Olson JA, Marks JR, Nevins JR. Predicting the clinical status of human breast cancer by using gene expression profiles. Proceedings of the National Academy of Sciences of the United States of America. 98: 11462-7. PMID 11562467 DOI: 10.1073/Pnas.201162998 |
0.371 |
|
| 2001 |
Ishida S, Huang E, Zuzan H, Spang R, Leone G, West M, Nevins JR. Role for E2F in control of both DNA replication and mitotic functions as revealed from DNA microarray analysis. Molecular and Cellular Biology. 21: 4684-99. PMID 11416145 DOI: 10.1128/Mcb.21.14.4684-4699.2001 |
0.389 |
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