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Erik C. Hett, Ph.D. - Publications

Affiliations: 
2007 Harvard University, Cambridge, MA, United States 
Area:
Microbiology Biology
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23 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Datta S, Chen DY, Tavares AH, Reyes-Robles T, Ryu KA, Khan N, Bechtel TJ, Bertoch JM, White CH, Hazuda DJ, Vora KA, Hett EC, Fadeyi OO, Oslund RC, Emili A, et al. High-resolution photocatalytic mapping of SARS-CoV-2 spike interactions on the cell surface. Cell Chemical Biology. PMID 37499664 DOI: 10.1016/j.chembiol.2023.06.028  0.322
2021 Datta S, Hett EC, Vora KA, Hazuda DJ, Oslund RC, Fadeyi OO, Emili A. The chemical biology of coronavirus host-cell interactions. Rsc Chemical Biology. 2: 30-46. PMID 34458775 DOI: 10.1039/d0cb00197j  0.309
2019 Gustine JN, Au MB, Haserick JR, Hett EC, Rubin EJ, Gibson FC, Deng LL. Cell Wall Hydrolytic Enzymes Enhance Antimicrobial Drug Activity Against Mycobacterium. Current Microbiology. PMID 30603964 DOI: 10.1007/S00284-018-1620-Z  0.531
2018 Henry KL, Kellner D, Bajrami B, Anderson JE, Beyna M, Bhisetti G, Cameron T, Capacci AG, Bertolotti-Ciarlet A, Feng J, Gao B, Hopkins B, Jenkins T, Li K, May-Dracka T, ... ... Hett EC, et al. CDK12-mediated transcriptional regulation of noncanonical NF-κB components is essential for signaling. Science Signaling. 11. PMID 30065029 DOI: 10.1126/Scisignal.Aam8216  0.343
2017 Li J, Wang B, Juba BM, Vazquez M, Kortum SW, Pierce BS, Pacheco M, Roberts L, Strohbach JW, Jones LH, Hett E, Thorarensen A, Telliez JB, Sharei A, Bunnage M, et al. Microfluidic-enabled intracellular delivery of membrane impermeable inhibitors to study target engagement in human primary cells. Acs Chemical Biology. PMID 29088528 DOI: 10.1021/Acschembio.7B00683  0.458
2017 Fadeyi OO, Hoth LR, Choi C, Feng X, Gopalsamy A, Hett EC, Kyne RE, Robinson RP, Jones LH. Covalent Enzyme Inhibition through Fluorosulfate Modification of a Non-Catalytic Serine Residue. Acs Chemical Biology. PMID 28718624 DOI: 10.1021/Acschembio.7B00403  0.401
2016 Telliez JB, Dowty ME, Wang L, Jussif J, Lin T, Li L, Moy E, Balbo P, Li W, Zhao Y, Crouse K, Dickinson C, Symanowicz P, Hegen M, Banker ME, ... ... Hett E, et al. Discovery of a novel JAK3-selective inhibitor: Functional differentiation of JAK3-selective inhibition over pan-JAK or JAK1-selective inhibition. Acs Chemical Biology. PMID 27791347 DOI: 10.1021/Acschembio.6B00677  0.344
2016 Hett EC, Kyne RE, Gopalsamy A, Tones MA, Xu H, Thio GL, Nolan E, Jones LH. Selectivity determination of a small molecule chemical probe using protein microarray and affinity capture techniques. Acs Combinatorial Science. PMID 27494431 DOI: 10.1021/Acscombsci.6B00089  0.409
2016 Xu H, Gopalsamy A, Hett EC, Salter S, Aulabaugh A, Kyne RE, Pierce B, Jones LH. Cellular thermal shift and clickable chemical probe assays for the determination of drug-target engagement in live cells. Organic & Biomolecular Chemistry. PMID 27216142 DOI: 10.1039/C6Ob01078D  0.408
2015 Bunnage ME, Gilbert AM, Jones LH, Hett EC. Know your target, know your molecule. Nature Chemical Biology. 11: 368-72. PMID 25978985 DOI: 10.1038/Nchembio.1813  0.322
2015 Xu H, Hett EC, Gopalsamy A, Parikh MD, Geoghegan KF, Kyne RE, Menard CA, Narayanan A, Robinson RP, Johnson DS, Tones MA, Jones LH. A library approach to rapidly discover photoaffinity probes of the mRNA decapping scavenger enzyme DcpS. Molecular Biosystems. PMID 25959423 DOI: 10.1039/C5Mb00288E  0.384
2015 Hett EC, Xu H, Geoghegan KF, Gopalsamy A, Kyne RE, Menard CA, Narayanan A, Parikh MD, Liu S, Roberts L, Robinson RP, Tones MA, Jones LH. Rational targeting of active-site tyrosine residues using sulfonyl fluoride probes. Acs Chemical Biology. 10: 1094-8. PMID 25571984 DOI: 10.1021/Cb5009475  0.415
2015 Hett EC, Piatnitski Chekler EL, Basak A, Bonin PD, Denny RA, Flick AC, Geoghegan KF, Liu S, Pletcher MT, Sahasrabudhe P, Salter SC, Stock IA, Taylor AP, Jones LH. Direct photocapture of bromodomains using tropolone chemical probes Medchemcomm. 6: 1018-1023. DOI: 10.1039/C5Md00070J  0.378
2014 Lanning BR, Whitby LR, Dix MM, Douhan J, Gilbert AM, Hett EC, Johnson TO, Joslyn C, Kath JC, Niessen S, Roberts LR, Schnute ME, Wang C, Hulce JJ, Wei B, et al. A road map to evaluate the proteome-wide selectivity of covalent kinase inhibitors. Nature Chemical Biology. 10: 760-7. PMID 25038787 DOI: 10.1038/Nchembio.1582  0.391
2013 Slater LH, Hett EC, Clatworthy AE, Mark KG, Hung DT. CCT chaperonin complex is required for efficient delivery of anthrax toxin into the cytosol of host cells. Proceedings of the National Academy of Sciences of the United States of America. 110: 9932-7. PMID 23716698 DOI: 10.1073/Pnas.1302257110  0.641
2013 Hett EC, Slater LH, Mark KG, Kawate T, Monks BG, Stutz A, Latz E, Hung DT. Chemical genetics reveals a kinase-independent role for protein kinase R in pyroptosis. Nature Chemical Biology. 9: 398-405. PMID 23603659 DOI: 10.1038/Nchembio.1236  0.606
2013 Slater LH, Hett EC, Mark K, Chumbler NM, Patel D, Lacy DB, Collier RJ, Hung DT. Identification of novel host-targeted compounds that protect from anthrax lethal toxin-induced cell death. Acs Chemical Biology. 8: 812-22. PMID 23343607 DOI: 10.1021/Cb300555N  0.637
2010 Hett EC, Chao MC, Rubin EJ. Interaction and modulation of two antagonistic cell wall enzymes of mycobacteria. Plos Pathogens. 6: e1001020. PMID 20686708 DOI: 10.1371/Journal.Ppat.1001020  0.653
2009 Hett EC, Hung DT. Targeting multiple biofilm pathways. Chemistry & Biology. 16: 1216-8. PMID 20064430 DOI: 10.1016/J.Chembiol.2009.12.003  0.592
2008 Hett EC, Chao MC, Deng LL, Rubin EJ. A mycobacterial enzyme essential for cell division synergizes with resuscitation-promoting factor. Plos Pathogens. 4: e1000001. PMID 18463693 DOI: 10.1371/Journal.Ppat.1000001  0.668
2008 Hett EC, Rubin EJ. Bacterial growth and cell division: a mycobacterial perspective. Microbiology and Molecular Biology Reviews : Mmbr. 72: 126-56, table of con. PMID 18322037 DOI: 10.1128/Mmbr.00028-07  0.535
2008 Rengarajan J, Murphy E, Park A, Krone CL, Hett EC, Bloom BR, Glimcher LH, Rubin EJ. Mycobacterium tuberculosis Rv2224c modulates innate immune responses. Proceedings of the National Academy of Sciences of the United States of America. 105: 264-9. PMID 18172199 DOI: 10.1073/Pnas.0710601105  0.533
2007 Hett EC, Chao MC, Steyn AJ, Fortune SM, Deng LL, Rubin EJ. A partner for the resuscitation-promoting factors of Mycobacterium tuberculosis. Molecular Microbiology. 66: 658-68. PMID 17919286 DOI: 10.1111/J.1365-2958.2007.05945.X  0.683
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