Spyros Artavanis-Tsakonas - Publications

Affiliations: 
Harvard Medical School, Boston, MA, United States 
Area:
notch signaling
Website:
http://artavanis-tsakonas.med.harvard.edu/

142 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Kankel MW, Sen A, Lu L, Theodorou M, Dimlich DN, McCampbell A, Henderson CE, Shneider NA, Artavanis-Tsakonas S. Amyotrophic Lateral Sclerosis Modifiers in Reveal the Phospholipase D Pathway as a Potential Therapeutic Target. Genetics. PMID 32345615 DOI: 10.1534/Genetics.119.302985  0.793
2019 Sarraf SA, Sideris DP, Giagtzoglou N, Ni L, Kankel MW, Sen A, Bochicchio LE, Huang CH, Nussenzweig SC, Worley SH, Morton PD, Artavanis-Tsakonas S, Youle RJ, Pickrell AM. PINK1/Parkin Influences Cell Cycle by Sequestering TBK1 at Damaged Mitochondria, Inhibiting Mitosis. Cell Reports. 29: 225-235.e5. PMID 31577952 DOI: 10.1016/J.Celrep.2019.08.085  0.802
2019 Ho DM, Artavanis-Tsakonas S, Louvi A. The Notch pathway in CNS homeostasis and neurodegeneration. Wiley Interdisciplinary Reviews. Developmental Biology. e358. PMID 31502763 DOI: 10.1002/Wdev.358  0.345
2018 Ho DM, Guruharsha KG, Artavanis-Tsakonas S. The Notch Interactome: Complexity in Signaling Circuitry. Advances in Experimental Medicine and Biology. 1066: 125-140. PMID 30030825 DOI: 10.1007/978-3-319-89512-3_7  0.509
2018 Engler A, Rolando C, Giachino C, Saotome I, Erni A, Brien C, Zhang R, Zimber-Strobl U, Radtke F, Artavanis-Tsakonas S, Louvi A, Taylor V. Notch2 Signaling Maintains NSC Quiescence in the Murine Ventricular-Subventricular Zone. Cell Reports. 22: 992-1002. PMID 29386140 DOI: 10.1016/j.celrep.2017.12.094  0.39
2017 Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, ... ... Artavanis-Tsakonas S, et al. Architecture of the human interactome defines protein communities and disease networks. Nature. PMID 28514442 DOI: 10.1038/Nature22366  0.389
2016 Ho DM, Artavanis-Tsakonas S. The Notch-Mediated Proliferation Circuitry. Current Topics in Developmental Biology. 116: 17-33. PMID 26970611 DOI: 10.1016/Bs.Ctdb.2015.12.016  0.517
2015 Stoiber MH, Olson S, May GE, Duff MO, Manent J, Obar R, Guruharsha K, Artavanis-Tsakonas S, Brown JB, Graveley BR, Celniker SE. Extensive cross-regulation of post-transcriptional regulatory networks in Drosophila. Genome Research. PMID 26294687 DOI: 10.1101/Gr.182675.114  0.325
2015 Ho DM, Pallavi SK, Artavanis-Tsakonas S. The Notch-mediated hyperplasia circuitry in Drosophila reveals a Src-JNK signaling axis. Elife. 4: e05996. PMID 26222204 DOI: 10.7554/Elife.05996  0.468
2015 Huttlin EL, Ting L, Bruckner RJ, Gebreab F, Gygi MP, Szpyt J, Tam S, Zarraga G, Colby G, Baltier K, Dong R, Guarani V, Vaites LP, Ordureau A, Rad R, ... ... Artavanis-Tsakonas S, et al. The BioPlex Network: A Systematic Exploration of the Human Interactome. Cell. 162: 425-40. PMID 26186194 DOI: 10.1016/J.Cell.2015.06.043  0.341
2015 Ho DM, Pallavi S, Artavanis-Tsakonas S. Author response: The Notch-mediated hyperplasia circuitry in Drosophila reveals a Src-JNK signaling axis Elife. DOI: 10.7554/Elife.05996.022  0.411
2015 Ho DM, Pallavi SK, Artavanis-Tsakonas S. The notch-mediated hyperplasia circuitry in drosophila reveals a Src-JNK signaling axis Elife. 4. DOI: 10.7554/eLife.05996  0.35
2014 Rhee DY, Cho DY, Zhai B, Slattery M, Ma L, Mintseris J, Wong CY, White KP, Celniker SE, Przytycka TM, Gygi SP, Obar RA, Artavanis-Tsakonas S. Transcription factor networks in Drosophila melanogaster. Cell Reports. 8: 2031-43. PMID 25242320 DOI: 10.1016/J.Celrep.2014.08.038  0.726
2014 Guruharsha KG, Hori K, Obar RA, Artavanis-Tsakonas S. Proteomic analysis of the Notch interactome. Methods in Molecular Biology (Clifton, N.J.). 1187: 181-92. PMID 25053490 DOI: 10.1007/978-1-4939-1139-4_14  0.802
2014 Hori K, Sen A, Artavanis-Tsakonas S. Genetic circuitry modulating notch signals through endosomal trafficking. Methods in Enzymology. 534: 283-99. PMID 24359960 DOI: 10.1016/B978-0-12-397926-1.00016-0  0.822
2013 Oh P, Lobry C, Gao J, Tikhonova A, Loizou E, Manent J, Manet J, van Handel B, Ibrahim S, Greve J, Mikkola H, Artavanis-Tsakonas S, Aifantis I. In vivo mapping of notch pathway activity in normal and stress hematopoiesis. Cell Stem Cell. 13: 190-204. PMID 23791481 DOI: 10.1016/J.Stem.2013.07.009  0.486
2013 Sen A, Dimlich DN, Guruharsha KG, Kankel MW, Hori K, Yokokura T, Brachat S, Richardson D, Loureiro J, Sivasankaran R, Curtis D, Davidow LS, Rubin LL, Hart AC, Van Vactor D, ... Artavanis-Tsakonas S, et al. Genetic circuitry of Survival motor neuron, the gene underlying spinal muscular atrophy. Proceedings of the National Academy of Sciences of the United States of America. 110: E2371-80. PMID 23757500 DOI: 10.1073/Pnas.1301738110  0.781
2013 Hori K, Sen A, Artavanis-Tsakonas S. Notch signaling at a glance. Journal of Cell Science. 126: 2135-40. PMID 23729744 DOI: 10.1242/Jcs.127308  0.832
2013 Å ale S, Lafkas D, Artavanis-Tsakonas S. Notch2 genetic fate mapping reveals two previously unrecognized mammary epithelial lineages. Nature Cell Biology. 15: 451-60. PMID 23604318 DOI: 10.1038/ncb2725  0.394
2013 Fleming RJ, Hori K, Sen A, Filloramo GV, Langer JM, Obar RA, Artavanis-Tsakonas S, Maharaj-Best AC. An extracellular region of Serrate is essential for ligand-induced cis-inhibition of Notch signaling. Development (Cambridge, England). 140: 2039-49. PMID 23571220 DOI: 10.1242/Dev.087916  0.805
2012 Guruharsha KG, Obar RA, Mintseris J, Aishwarya K, Krishnan RT, Vijayraghavan K, Artavanis-Tsakonas S. Drosophila protein interaction map (DPiM): a paradigm for metazoan protein complex interactions. Fly. 6: 246-53. PMID 23222005 DOI: 10.4161/Fly.22108  0.36
2012 Hori K, Sen A, Kirchhausen T, Artavanis-Tsakonas S. Regulation of ligand-independent Notch signal through intracellular trafficking. Communicative & Integrative Biology. 5: 374-6. PMID 23060962 DOI: 10.4161/Cib.19995  0.816
2012 Guruharsha KG, Kankel MW, Artavanis-Tsakonas S. The Notch signalling system: recent insights into the complexity of a conserved pathway. Nature Reviews. Genetics. 13: 654-66. PMID 22868267 DOI: 10.1038/Nrg3272  0.809
2012 Louvi A, Artavanis-Tsakonas S. Notch and disease: a growing field. Seminars in Cell & Developmental Biology. 23: 473-80. PMID 22373641 DOI: 10.1016/j.semcdb.2012.02.005  0.45
2012 Sale S, Lafkas D, Artavanis-Tsakonas S. Abstract LB-208: Notch2 in vivo genetic labeling reveals novel epithelial subtypes within mammary luminal lineage Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-208  0.373
2011 Hori K, Sen A, Kirchhausen T, Artavanis-Tsakonas S. Synergy between the ESCRT-III complex and Deltex defines a ligand-independent Notch signal. The Journal of Cell Biology. 195: 1005-15. PMID 22162134 DOI: 10.1083/Jcb.201104146  0.829
2011 Guruharsha KG, Rual JF, Zhai B, Mintseris J, Vaidya P, Vaidya N, Beekman C, Wong C, Rhee DY, Cenaj O, McKillip E, Shah S, Stapleton M, Wan KH, Yu C, ... ... Artavanis-Tsakonas S, et al. A protein complex network of Drosophila melanogaster. Cell. 147: 690-703. PMID 22036573 DOI: 10.1016/J.Cell.2011.08.047  0.676
2011 Fre S, Hannezo E, Sale S, Huyghe M, Lafkas D, Kissel H, Louvi A, Greve J, Louvard D, Artavanis-Tsakonas S. Notch lineages and activity in intestinal stem cells determined by a new set of knock-in mice. Plos One. 6: e25785. PMID 21991352 DOI: 10.1371/Journal.Pone.0025785  0.42
2011 Arboleda-Velasquez JF, Manent J, Lee JH, Tikka S, Ospina C, Vanderburg CR, Frosch MP, Rodríguez-Falcón M, Villen J, Gygi S, Lopera F, Kalimo H, Moskowitz MA, Ayata C, Louvi A, ... Artavanis-Tsakonas S, et al. Hypomorphic Notch 3 alleles link Notch signaling to ischemic cerebral small-vessel disease. Proceedings of the National Academy of Sciences of the United States of America. 108: E128-35. PMID 21555590 DOI: 10.1073/Pnas.1101964108  0.701
2011 Sun Y, Klauzinska M, Lake RJ, Lee JM, Santopietro S, Raafat A, Salomon D, Callahan R, Artavanis-Tsakonas S. Trp53 regulates Notch 4 signaling through Mdm2. Journal of Cell Science. 124: 1067-76. PMID 21402876 DOI: 10.1242/jcs.068965  0.487
2011 Sen A, Yokokura T, Kankel MW, Dimlich DN, Manent J, Sanyal S, Artavanis-Tsakonas S. Modeling spinal muscular atrophy in Drosophila links Smn to FGF signaling. The Journal of Cell Biology. 192: 481-95. PMID 21300852 DOI: 10.1083/Jcb.201004016  0.809
2010 Dimitriadi M, Sleigh JN, Walker A, Chang HC, Sen A, Kalloo G, Harris J, Barsby T, Walsh MB, Satterlee JS, Li C, Van Vactor D, Artavanis-Tsakonas S, Hart AC. Conserved genes act as modifiers of invertebrate SMN loss of function defects. Plos Genetics. 6: e1001172. PMID 21124729 DOI: 10.1371/Journal.Pgen.1001172  0.547
2010 Artavanis-Tsakonas S, Muskavitch MA. Notch: the past, the present, and the future. Current Topics in Developmental Biology. 92: 1-29. PMID 20816391 DOI: 10.1016/S0070-2153(10)92001-2  0.686
2010 Kelly DF, Lake RJ, Middelkoop TC, Fan HY, Artavanis-Tsakonas S, Walz T. Molecular structure and dimeric organization of the Notch extracellular domain as revealed by electron microscopy. Plos One. 5: e10532. PMID 20479883 DOI: 10.1371/Journal.Pone.0010532  0.4
2010 Mazzone M, Selfors LM, Albeck J, Overholtzer M, Sale S, Carroll DL, Pandya D, Lu Y, Mills GB, Aster JC, Artavanis-Tsakonas S, Brugge JS. Dose-dependent induction of distinct phenotypic responses to Notch pathway activation in mammary epithelial cells. Proceedings of the National Academy of Sciences of the United States of America. 107: 5012-7. PMID 20194747 DOI: 10.1073/Pnas.1000896107  0.444
2009 Lake RJ, Grimm LM, Veraksa A, Banos A, Artavanis-Tsakonas S. In vivo analysis of the Notch receptor S1 cleavage. Plos One. 4: e6728. PMID 19701455 DOI: 10.1371/Journal.Pone.0006728  0.741
2009 Fre S, Pallavi SK, Huyghe M, Laé M, Janssen KP, Robine S, Artavanis-Tsakonas S, Louvard D. Notch and Wnt signals cooperatively control cell proliferation and tumorigenesis in the intestine. Proceedings of the National Academy of Sciences of the United States of America. 106: 6309-14. PMID 19251639 DOI: 10.1073/Pnas.0900427106  0.46
2009 Hurlbut GD, Kankel MW, Artavanis-Tsakonas S. Nodal points and complexity of Notch-Ras signal integration. Proceedings of the National Academy of Sciences of the United States of America. 106: 2218-23. PMID 19171888 DOI: 10.1073/Pnas.0812024106  0.808
2008 Chang HC, Dimlich DN, Yokokura T, Mukherjee A, Kankel MW, Sen A, Sridhar V, Fulga TA, Hart AC, Van Vactor D, Artavanis-Tsakonas S. Modeling spinal muscular atrophy in Drosophila. Plos One. 3: e3209. PMID 18791638 DOI: 10.1371/Journal.Pone.0003209  0.81
2008 Arboleda-Velasquez JF, Zhou Z, Shin HK, Louvi A, Kim HH, Savitz SI, Liao JK, Salomone S, Ayata C, Moskowitz MA, Artavanis-Tsakonas S. Linking Notch signaling to ischemic stroke. Proceedings of the National Academy of Sciences of the United States of America. 105: 4856-61. PMID 18347334 DOI: 10.1073/Pnas.0709867105  0.71
2007 Kankel MW, Hurlbut GD, Upadhyay G, Yajnik V, Yedvobnick B, Artavanis-Tsakonas S. Investigating the genetic circuitry of mastermind in Drosophila, a notch signal effector. Genetics. 177: 2493-505. PMID 18073442 DOI: 10.1534/Genetics.107.080994  0.825
2007 Kelly DF, Lake RJ, Walz T, Artavanis-Tsakonas S. Conformational variability of the intracellular domain of Drosophila Notch and its interaction with Suppressor of Hairless. Proceedings of the National Academy of Sciences of the United States of America. 104: 9591-6. PMID 17535912 DOI: 10.1073/Pnas.0702887104  0.463
2007 Hurlbut GD, Kankel MW, Lake RJ, Artavanis-Tsakonas S. Crossing paths with Notch in the hyper-network. Current Opinion in Cell Biology. 19: 166-75. PMID 17317139 DOI: 10.1016/J.Ceb.2007.02.012  0.802
2006 Klinakis A, Szabolcs M, Politi K, Kiaris H, Artavanis-Tsakonas S, Efstratiadis A. Myc is a Notch1 transcriptional target and a requisite for Notch1-induced mammary tumorigenesis in mice. Proceedings of the National Academy of Sciences of the United States of America. 103: 9262-7. PMID 16751266 DOI: 10.1073/Pnas.0603371103  0.35
2006 Louvi A, Arboleda-Velasquez JF, Artavanis-Tsakonas S. CADASIL: a critical look at a Notch disease. Developmental Neuroscience. 28: 5-12. PMID 16508299 DOI: 10.1159/000090748  0.696
2006 Mourikis P, Hurlbut GD, Artavanis-Tsakonas S. Enigma, a mitochondrial protein affecting lifespan and oxidative stress response in Drosophila. Proceedings of the National Academy of Sciences of the United States of America. 103: 1307-12. PMID 16434470 DOI: 10.1073/pnas.0510564103  0.774
2006 Louvi A, Artavanis-Tsakonas S. Notch signalling in vertebrate neural development. Nature Reviews. Neuroscience. 7: 93-102. PMID 16429119 DOI: 10.1038/nrn1847  0.508
2005 Mukherjee A, Veraksa A, Bauer A, Rosse C, Camonis J, Artavanis-Tsakonas S. Regulation of Notch signalling by non-visual beta-arrestin. Nature Cell Biology. 7: 1191-201. PMID 16284625 DOI: 10.1038/Ncb1327  0.747
2005 Fre S, Huyghe M, Mourikis P, Robine S, Louvard D, Artavanis-Tsakonas S. Notch signals control the fate of immature progenitor cells in the intestine. Nature. 435: 964-8. PMID 15959516 DOI: 10.1038/Nature03589  0.44
2005 Veraksa A, Bauer A, Artavanis-Tsakonas S. Analyzing protein complexes in Drosophila with tandem affinity purification-mass spectrometry. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 232: 827-34. PMID 15704125 DOI: 10.1002/Dvdy.20272  0.712
2004 Kiaris H, Politi K, Grimm LM, Szabolcs M, Fisher P, Efstratiadis A, Artavanis-Tsakonas S. Modulation of notch signaling elicits signature tumors and inhibits hras1-induced oncogenesis in the mouse mammary epithelium. The American Journal of Pathology. 165: 695-705. PMID 15277242 DOI: 10.1016/S0002-9440(10)63333-0  0.396
2004 Moberg KH, Mukherjee A, Veraksa A, Artavanis-Tsakonas S, Hariharan IK. The Drosophila F box protein archipelago regulates dMyc protein levels in vivo. Current Biology : Cb. 14: 965-74. PMID 15182669 DOI: 10.1016/J.Cub.2004.04.040  0.727
2003 Beltran S, Blanco E, Serras F, Pérez-Villamil B, Guigó R, Artavanis-Tsakonas S, Corominas M. Transcriptional network controlled by the trithorax-group gene ash2 in Drosophila melanogaster. Proceedings of the National Academy of Sciences of the United States of America. 100: 3293-8. PMID 12626737 DOI: 10.1073/pnas.0538075100  0.387
2003 Grandbarbe L, Bouissac J, Rand M, Hrabé de Angelis M, Artavanis-Tsakonas S, Mohier E. Delta-Notch signaling controls the generation of neurons/glia from neural stem cells in a stepwise process. Development (Cambridge, England). 130: 1391-402. PMID 12588854 DOI: 10.1242/Dev.00374  0.683
2002 Mishra-Gorur K, Rand MD, Perez-Villamil B, Artavanis-Tsakonas S. Down-regulation of Delta by proteolytic processing. The Journal of Cell Biology. 159: 313-24. PMID 12403816 DOI: 10.1083/Jcb.200203117  0.75
2002 Matsuno K, Ito M, Hori K, Miyashita F, Suzuki S, Kishi N, Artavanis-Tsakonas S, Okano H. Involvement of a proline-rich motif and RING-H2 finger of Deltex in the regulation of Notch signaling. Development (Cambridge, England). 129: 1049-59. PMID 11861487  0.808
2002 Kiaris H, Schally AV, Busto R, Halmos G, Artavanis-Tsakonas S, Varga JL. Expression of a splice variant of the receptor for GHRH in 3T3 fibroblasts activates cell proliferation responses to GHRH analogs. Proceedings of the National Academy of Sciences of the United States of America. 99: 196-200. PMID 11773624 DOI: 10.1073/Pnas.012590999  0.329
2001 Kishi N, Tang Z, Maeda Y, Hirai A, Mo R, Ito M, Suzuki S, Nakao K, Kinoshita T, Kadesch T, Hui C, Artavanis-Tsakonas S, Okano H, Matsuno K. Murine homologs of deltex define a novel gene family involved in vertebrate Notch signaling and neurogenesis. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 19: 21-35. PMID 11226752 DOI: 10.1016/S0736-5748(00)00071-X  0.805
2000 Wu L, Aster JC, Blacklow SC, Lake R, Artavanis-Tsakonas S, Griffin JD. MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors. Nature Genetics. 26: 484-9. PMID 11101851 DOI: 10.1038/82644  0.543
2000 Kurata S, Go MJ, Artavanis-Tsakonas S, Gehring WJ. Notch signaling and the determination of appendage identity. Proceedings of the National Academy of Sciences of the United States of America. 97: 2117-22. PMID 10681430 DOI: 10.1073/pnas.040556497  0.652
2000 Rand MD, Grimm LM, Artavanis-Tsakonas S, Patriub V, Blacklow SC, Sklar J, Aster JC. Calcium depletion dissociates and activates heterodimeric notch receptors. Molecular and Cellular Biology. 20: 1825-35. PMID 10669757 DOI: 10.1128/Mcb.20.5.1825-1835.2000  0.68
1999 Hing HK, Bangalore L, Sun X, Artavanis-Tsakonas S. Mutations in the heatshock cognate 70 protein (hsc4) modulate Notch signaling. European Journal of Cell Biology. 78: 690-7. PMID 10569241 DOI: 10.1016/S0171-9335(99)80037-5  0.81
1999 Sestan N, Artavanis-Tsakonas S, Rakic P. Contact-dependent inhibition of cortical neurite growth mediated by notch signaling. Science (New York, N.Y.). 286: 741-6. PMID 10531053 DOI: 10.1126/science.286.5440.741  0.335
1999 Purcell K, Artavanis-Tsakonas S. The developmental role of warthog, the notch modifier encoding Drab6. The Journal of Cell Biology. 146: 731-40. PMID 10459009 DOI: 10.1083/jcb.146.4.731  0.482
1999 Cornell M, Evans DA, Mann R, Fostier M, Flasza M, Monthatong M, Artavanis-Tsakonas S, Baron M. The Drosophila melanogaster Suppressor of deltex gene, a regulator of the Notch receptor signaling pathway, is an E3 class ubiquitin ligase. Genetics. 152: 567-76. PMID 10353900  0.455
1999 Artavanis-Tsakonas S, Rand MD, Lake RJ. Notch signaling: cell fate control and signal integration in development. Science (New York, N.Y.). 284: 770-6. PMID 10221902 DOI: 10.1126/Science.284.5415.770  0.741
1999 Gray GE, Mann RS, Mitsiadis E, Henrique D, Carcangiu ML, Banks A, Leiman J, Ward D, Ish-Horowitz D, Artavanis-Tsakonas S. Human ligands of the Notch receptor. The American Journal of Pathology. 154: 785-94. PMID 10079256 DOI: 10.1016/S0002-9440(10)65325-4  0.609
1999 Qi H, Rand MD, Wu X, Sestan N, Wang W, Rakic P, Xu T, Artavanis-Tsakonas S. Processing of the notch ligand delta by the metalloprotease Kuzbanian. Science (New York, N.Y.). 283: 91-4. PMID 9872749 DOI: 10.1126/Science.283.5398.91  0.806
1998 Fostier M, Evans DA, Artavanis-Tsakonas S, Baron M. Genetic characterization of the Drosophila melanogaster Suppressor of deltex gene: A regulator of notch signaling. Genetics. 150: 1477-85. PMID 9832525  0.439
1998 Go MJ, Artavanis-Tsakonas S. A genetic screen for novel components of the notch signaling pathway during Drosophila bristle development. Genetics. 150: 211-20. PMID 9725840  0.436
1998 Varnum-Finney B, Purton LE, Yu M, Brashem-Stein C, Flowers D, Staats S, Moore KA, Le Roux I, Mann R, Gray G, Artavanis-Tsakonas S, Bernstein ID. The Notch ligand, Jagged-1, influences the development of primitive hematopoietic precursor cells. Blood. 91: 4084-91. PMID 9596653 DOI: 10.1182/Blood.V91.11.4084.411K05_4084_4091  0.377
1998 Matsuno K, Eastman D, Mitsiades T, Quinn AM, Carcanciu ML, Ordentlich P, Kadesch T, Artavanis-Tsakonas S. Human deltex is a conserved regulator of Notch signalling. Nature Genetics. 19: 74-8. PMID 9590294 DOI: 10.1038/Ng0598-74  0.843
1998 Go MJ, Eastman DS, Artavanis-Tsakonas S. Cell proliferation control by Notch signaling in Drosophila development. Development (Cambridge, England). 125: 2031-40. PMID 9570768  0.669
1998 Ordentlich P, Lin A, Shen CP, Blaumueller C, Matsuno K, Artavanis-Tsakonas S, Kadesch T. Notch inhibition of E47 supports the existence of a novel signaling pathway. Molecular and Cellular Biology. 18: 2230-9. PMID 9528794 DOI: 10.1128/Mcb.18.4.2230  0.812
1997 Fleming RJ, Purcell K, Artavanis-Tsakonas S. The NOTCH receptor and its ligands. Trends in Cell Biology. 7: 437-41. PMID 17709001 DOI: 10.1016/S0962-8924(97)01161-6  0.641
1997 Capobianco AJ, Zagouras P, Blaumueller CM, Artavanis-Tsakonas S, Bishop JM. Neoplastic transformation by truncated alleles of human NOTCH1/TAN1 and NOTCH2. Molecular and Cellular Biology. 17: 6265-73. PMID 9343387 DOI: 10.1128/MCB.17.11.6265  0.824
1997 Matsuno K, Go MJ, Sun X, Eastman DS, Artavanis-Tsakonas S. Suppressor of Hairless-independent events in Notch signaling imply novel pathway elements. Development (Cambridge, England). 124: 4265-73. PMID 9334275  0.686
1997 Sun X, Artavanis-Tsakonas S. Secreted forms of DELTA and SERRATE define antagonists of Notch signaling in Drosophila. Development (Cambridge, England). 124: 3439-48. PMID 9310338  0.395
1997 Blaumueller CM, Qi H, Zagouras P, Artavanis-Tsakonas S. Intracellular cleavage of Notch leads to a heterodimeric receptor on the plasma membrane. Cell. 90: 281-91. PMID 9244302 DOI: 10.1016/S0092-8674(00)80336-0  0.794
1997 Artavanis-Tsakonas S. Alagille syndrome--a notch up for the Notch receptor. Nature Genetics. 16: 212-3. PMID 9207778 DOI: 10.1038/ng0797-212  0.316
1997 Blaumueller CM, Artavanis-Tsakonas S. Comparative aspects of Notch signaling in lower and higher eukaryotes. Perspectives On Developmental Neurobiology. 4: 325-43. PMID 9171446  0.837
1996 Verheyen EM, Purcell KJ, Fortini ME, Artavanis-Tsakonas S. Analysis of dominant enhancers and suppressors of activated Notch in Drosophila. Genetics. 144: 1127-41. PMID 8913755  0.777
1996 Liu Y, Dehni G, Purcell KJ, Sokolow J, Carcangiu ML, Artavanis-Tsakonas S, Stifani S. Epithelial expression and chromosomal location of human TLE genes: implications for notch signaling and neoplasia. Genomics. 31: 58-64. PMID 8808280 DOI: 10.1006/Geno.1996.0009  0.433
1996 Sun X, Artavanis-Tsakonas S. The intracellular deletions of Delta and Serrate define dominant negative forms of the Drosophila Notch ligands. Development (Cambridge, England). 122: 2465-74. PMID 8756291  0.366
1996 Axelrod JD, Matsuno K, Artavanis-Tsakonas S, Perrimon N. Interaction between Wingless and Notch signaling pathways mediated by dishevelled. Science (New York, N.Y.). 271: 1826-32. PMID 8596950 DOI: 10.1126/Science.271.5257.1826  0.788
1995 Ahmad I, Zaqouras P, Artavanis-Tsakonas S. Involvement of Notch-1 in mammalian retinal neurogenesis: association of Notch-1 activity with both immature and terminally differentiated cells. Mechanisms of Development. 53: 73-85. PMID 8555113 DOI: 10.1016/0925-4773(95)00425-4  0.439
1995 Dawson IA, Roth S, Artavanis-Tsakonas S. The Drosophila cell cycle gene fizzy is required for normal degradation of cyclins A and B during mitosis and has homology to the CDC20 gene of Saccharomyces cerevisiae. The Journal of Cell Biology. 129: 725-37. PMID 7730407 DOI: 10.1083/Jcb.129.3.725  0.389
1995 Artavanis-Tsakonas S, Matsuno K, Fortini ME. Notch signaling. Science (New York, N.Y.). 268: 225-32. PMID 7716513  0.726
1995 Matsuno K, Diederich RJ, Go MJ, Blaumueller CM, Artavanis-Tsakonas S. Deltex acts as a positive regulator of Notch signaling through interactions with the Notch ankyrin repeats. Development (Cambridge, England). 121: 2633-44. PMID 7671825  0.833
1995 Zagouras P, Stifani S, Blaumueller CM, Carcangiu ML, Artavanis-Tsakonas S. Alterations in Notch signaling in neoplastic lesions of the human cervix. Proceedings of the National Academy of Sciences of the United States of America. 92: 6414-8. PMID 7604005 DOI: 10.1073/pnas.92.14.6414  0.817
1994 Fehon RG, Dawson IA, Artavanis-Tsakonas S. A Drosophila homologue of membrane-skeleton protein 4.1 is associated with septate junctions and is encoded by the coracle gene. Development (Cambridge, England). 120: 545-57. PMID 8162854  0.695
1994 Diederich RJ, Matsuno K, Hing H, Artavanis-Tsakonas S. Cytosolic interaction between deltex and Notch ankyrin repeats implicates deltex in the Notch signaling pathway. Development (Cambridge, England). 120: 473-81. PMID 8162848  0.803
1994 Busseau I, Diederich RJ, Xu T, Artavanis-Tsakonas S. A member of the Notch group of interacting loci, deltex encodes a cytoplasmic basic protein. Genetics. 136: 585-96. PMID 8150285  0.375
1994 Fortini ME, Artavanis-Tsakonas S. The suppressor of hairless protein participates in notch receptor signaling. Cell. 79: 273-82. PMID 7954795 DOI: 10.1016/0092-8674(94)90196-1  0.713
1994 Hing HK, Sun X, Artavanis-Tsakonas S. Modulation of wingless signaling by Notch in Drosophila. Mechanisms of Development. 47: 261-8. PMID 7848873 DOI: 10.1016/0925-4773(94)90044-2  0.831
1993 Fortini ME, Rebay I, Caron LA, Artavanis-Tsakonas S. An activated Notch receptor blocks cell-fate commitment in the developing Drosophila eye. Nature. 365: 555-7. PMID 8413612 DOI: 10.1038/365555A0  0.806
1993 Heintzelman MB, Frankel SA, Artavanis-Tsakonas S, Mooseker MS. Cloning of a secretory gelsolin from Drosophila melanogaster. Journal of Molecular Biology. 230: 709-16. PMID 8386771 DOI: 10.1006/jmbi.1993.1191  0.341
1993 Rebay I, Fehon RG, Artavanis-Tsakonas S. Specific truncations of Drosophila Notch define dominant activated and dominant negative forms of the receptor. Cell. 74: 319-29. PMID 8343959 DOI: 10.1016/0092-8674(93)90423-N  0.825
1993 Fortini ME, Artavanis-Tsakonas S. Notch: neurogenesis is only part of the picture. Cell. 75: 1245-7. PMID 8269507 DOI: 10.1016/0092-8674(93)90611-S  0.652
1993 Dawson IA, Roth S, Akam M, Artavanis-Tsakonas S. Mutations of the fizzy locus cause metaphase arrest in Drosophila melanogaster embryos. Development (Cambridge, England). 117: 359-76. PMID 8223258  0.592
1993 Rebay I, Fortini ME, Artavanis-Tsakonas S. Analysis of phenotypic abnormalities and cell fate changes caused by dominant activated and dominant negative forms of the Notch receptor in Drosophila development. Comptes Rendus De L'Acadã©Mie Des Sciences. Sã©Rie Iii, Sciences De La Vie. 316: 1097-123. PMID 8076207  0.802
1992 Delidakis C, Artavanis-Tsakonas S. The Enhancer of split [E(spl)] locus of Drosophila encodes seven independent helix-loop-helix proteins. Proceedings of the National Academy of Sciences of the United States of America. 89: 8731-5. PMID 1528887 DOI: 10.1073/Pnas.89.18.8731  0.71
1992 Xu T, Caron LA, Fehon RG, Artavanis-Tsakonas S. The involvement of the Notch locus in Drosophila oogenesis. Development (Cambridge, England). 115: 913-22. PMID 1451667  0.71
1992 Rothberg JM, Artavanis-Tsakonas S. Modularity of the slit protein. Characterization of a conserved carboxy-terminal sequence in secreted proteins and a motif implicated in extracellular protein interactions. Journal of Molecular Biology. 227: 367-70. PMID 1404356 DOI: 10.1016/0022-2836(92)90891-M  0.347
1992 Stifani S, Blaumueller CM, Redhead NJ, Hill RE, Artavanis-Tsakonas S. Human homologs of a Drosophila Enhancer of split gene product define a novel family of nuclear proteins. Nature Genetics. 2: 343. PMID 1303292 DOI: 10.1038/ng1292-343a  0.787
1992 Stifani S, Blaumueller CM, Redhead NJ, Hill RE, Artavanis-Tsakonas S. Human homologs of a Drosophila Enhancer of split gene product define a novel family of nuclear proteins. Nature Genetics. 2: 119-27. PMID 1303260 DOI: 10.1038/ng1092-119  0.812
1991 Fehon RG, Johansen K, Rebay I, Artavanis-Tsakonas S. Complex cellular and subcellular regulation of notch expression during embryonic and imaginal development of Drosophila: implications for notch function. The Journal of Cell Biology. 113: 657-69. PMID 2016340 DOI: 10.1083/Jcb.113.3.657  0.801
1991 Markopoulou K, Artavanis-Tsakonas S. Developmental analysis of the facets, a group of intronic mutations at the Notch locus of Drosophila melanogaster that affect postembryonic development. The Journal of Experimental Zoology. 257: 314-29. PMID 1900884 DOI: 10.1002/Jez.1402570305  0.654
1991 Artavanis-Tsakonas S, Delidakis C, Fehon RG. The Notch locus and the cell biology of neuroblast segregation. Annual Review of Cell Biology. 7: 427-52. PMID 1809352 DOI: 10.1146/annurev.cb.07.110191.002235  0.826
1991 Delidakis C, Preiss A, Hartley DA, Artavanis-Tsakonas S. Two genetically and molecularly distinct functions involved in early neurogenesis reside within the Enhancer of split locus of Drosophila melanogaster. Genetics. 129: 803-23. PMID 1752423  0.723
1991 Artavanis-Tsakonas S, Simpson P. Choosing a cell fate: a view from the Notch locus. Trends in Genetics : Tig. 7: 403-8. PMID 1668193 DOI: 10.1016/0168-9525(91)90264-Q  0.354
1991 Rebay I, Fleming RJ, Fehon RG, Cherbas L, Cherbas P, Artavanis-Tsakonas S. Specific EGF repeats of Notch mediate interactions with Delta and Serrate: implications for Notch as a multifunctional receptor. Cell. 67: 687-99. PMID 1657403 DOI: 10.1016/0092-8674(91)90064-6  0.827
1990 Xu T, Rebay I, Fleming RJ, Scottgale TN, Artavanis-Tsakonas S. The Notch locus and the genetic circuitry involved in early Drosophila neurogenesis. Genes & Development. 4: 464-75. PMID 2338245 DOI: 10.1101/Gad.4.3.464  0.808
1990 Artavanis-Tsakonas S, Delidakis C, Fehon R, Hartley D, Herndon V, Johansen K, Markopoulou K, Preiss A, Rebay I, Scottgale N. Notch and the molecular genetics of neuroblast segregation in Drosophila. Molecular Reproduction and Development. 27: 23-7. PMID 2271182 DOI: 10.1002/Mrd.1080270107  0.762
1990 Fehon RG, Kooh PJ, Rebay I, Regan CL, Xu T, Muskavitch MA, Artavanis-Tsakonas S. Molecular interactions between the protein products of the neurogenic loci Notch and Delta, two EGF-homologous genes in Drosophila. Cell. 61: 523-34. PMID 2185893 DOI: 10.1016/0092-8674(90)90534-L  0.825
1990 Rothberg JM, Jacobs JR, Goodman CS, Artavanis-Tsakonas S. slit: an extracellular protein necessary for development of midline glia and commissural axon pathways contains both EGF and LRR domains. Genes & Development. 4: 2169-87. PMID 2176636 DOI: 10.1101/Gad.4.12A.2169  0.4
1990 Fleming RJ, Scottgale TN, Diederich RJ, Artavanis-Tsakonas S. The gene Serrate encodes a putative EGF-like transmembrane protein essential for proper ectodermal development in Drosophila melanogaster. Genes & Development. 4: 2188-201. PMID 2125287 DOI: 10.1101/Gad.4.12A.2188  0.612
1990 Xu T, Artavanis-Tsakonas S. deltex, a locus interacting with the neurogenic genes, Notch, Delta and mastermind in Drosophila melanogaster. Genetics. 126: 665-77. PMID 2123462  0.363
1989 Ramos RG, Grimwade BG, Wharton KA, Scottgale TN, Artavanis-Tsakonas S. Physical and functional definition of the Drosophila Notch locus by P element transformation. Genetics. 123: 337-48. PMID 2555253  0.808
1989 Markopoulou K, Welshons WJ, Artavanis-Tsakonas S. Phenotypic and molecular analysis of the facets, a group of intronic mutations at the Notch locus of Drosophila melanogaster which affect postembryonic development. Genetics. 122: 417-28. PMID 2548924  0.667
1989 Johansen KM, Fehon RG, Artavanis-Tsakonas S. The notch gene product is a glycoprotein expressed on the cell surface of both epidermal and neuronal precursor cells during Drosophila development. The Journal of Cell Biology. 109: 2427-40. PMID 2509485 DOI: 10.1083/Jcb.109.5.2427  0.723
1989 Markopoulou K, Artavanis-Tsakonas S. The expression of the neurogenic locus Notch during the postembryonic development of Drosophila melanogaster and its relationship to mitotic activity. Journal of Neurogenetics. 6: 11-26. PMID 2506320 DOI: 10.3109/01677068909107097  0.72
1988 Preiss A, Hartley DA, Artavanis-Tsakonas S. The molecular genetics of Enhancer of split, a gene required for embryonic neural development in Drosophila. The Embo Journal. 7: 3917-27. PMID 3145200 DOI: 10.1002/J.1460-2075.1988.Tb03278.X  0.633
1988 Rothberg JM, Hartley DA, Walther Z, Artavanis-Tsakonas S. slit: an EGF-homologous locus of D. melanogaster involved in the development of the embryonic central nervous system. Cell. 55: 1047-59. PMID 3144436 DOI: 10.1016/0092-8674(88)90249-8  0.578
1988 Hartley DA, Preiss A, Artavanis-Tsakonas S. A deduced gene product from the Drosophila neurogenic locus, enhancer of split, shows homology to mammalian G-protein beta subunit. Cell. 55: 785-95. PMID 3142687 DOI: 10.1016/0092-8674(88)90134-1  0.578
1988 Artavanis-Tsakonas S. The molecular biology of the Notch locus and the fine tuning of differentiation in Drosophila. Trends in Genetics : Tig. 4: 95-100. PMID 3070860 DOI: 10.1016/0168-9525(88)90096-0  0.422
1987 Hartley DA, Xu TA, Artavanis-Tsakonas S. The embryonic expression of the Notch locus of Drosophila melanogaster and the implications of point mutations in the extracellular EGF-like domain of the predicted protein. The Embo Journal. 6: 3407-17. PMID 3123218 DOI: 10.1002/J.1460-2075.1987.Tb02664.X  0.64
1985 Wharton KA, Johansen KM, Xu T, Artavanis-Tsakonas S. Nucleotide sequence from the neurogenic locus notch implies a gene product that shares homology with proteins containing EGF-like repeats. Cell. 43: 567-81. PMID 3935325 DOI: 10.1016/0092-8674(85)90229-6  0.703
1985 Grimwade BG, Muskavitch MA, Welshons WJ, Yedvobnick B, Artavanis-Tsakonas S. The molecular genetics of the Notch locus in Drosophila melanogaster. Developmental Biology. 107: 503-19. PMID 3918897 DOI: 10.1016/0012-1606(85)90331-8  0.821
1985 Wharton KA, Yedvobnick B, Finnerty VG, Artavanis-Tsakonas S. opa: a novel family of transcribed repeats shared by the Notch locus and other developmentally regulated loci in D. melanogaster. Cell. 40: 55-62. PMID 2981631 DOI: 10.1016/0092-8674(85)90308-3  0.612
1985 Yedvobnick B, Muskavitch MA, Wharton KA, Halpern ME, Paul E, Grimwade BG, Artavanis-Tsakonas S. Molecular genetics of Drosophila neurogenesis. Cold Spring Harbor Symposia On Quantitative Biology. 50: 841-54. PMID 2420520  0.79
1984 Artavanis-Tsakonas S, Grimwade BG, Harrison RG. The Notch locus of Drosophila melanogaster: A molecular anaylsis Developmental Genetics. 4: 233-254. DOI: 10.1002/Dvg.1020040403  0.8
1983 Artavanis-Tsakonas S, Muskavitch MA, Yedvobnick B. Molecular cloning of Notch, a locus affecting neurogenesis in Drosophila melanogaster. Proceedings of the National Academy of Sciences of the United States of America. 80: 1977-81. PMID 6403942 DOI: 10.1073/Pnas.80.7.1977  0.7
1981 Lis J, Neckameyer W, Mirault ME, Artavanis-Tsakonas S, Lall P, Martin G, Schedl P. DNA sequences flanking the starts of the hsp 70 and alpha beta heat shock genes are homologous. Developmental Biology. 83: 291-300. PMID 6263741 DOI: 10.1016/0012-1606(81)90475-9  0.66
1980 Dudler R, Egg AH, Kubli E, Artavanis-Tsakonas S, Gehring WJ, Steward R, Schedl P. Transfer RNA genes of Drosophila melanogaster. Nucleic Acids Research. 8: 2921-37. PMID 6776487 DOI: 10.1093/Nar/8.13.2921  0.608
1979 Ish-Horowicz D, Pinchin SM, Schedl P, Artavanis-Tsakonas S, Mirault ME. Genetic and molecular analysis of the 87A7 and 87C1 heat-inducible loci of D. melanogaster. Cell. 18: 1351-8. PMID 117906 DOI: 10.1016/0092-8674(79)90245-9  0.69
1979 Mirault ME, Goldschmidt-Clermont M, Artavanis-Tsakonas S, Schedl P. Organization of the multiple genes for the 70,000-dalton heat-shock protein in Drosophila melanogaster. Proceedings of the National Academy of Sciences of the United States of America. 76: 5254-8. PMID 116226 DOI: 10.1073/PNAS.76.10.5254  0.589
1979 Artavanis-Tsakonas S, Schedl P, Mirault ME, Moran L, Lis J. Genes for the 70,000 dalton heat shock protein in two cloned D. melanogaster DNA segments. Cell. 17: 9-18. PMID 110461 DOI: 10.1016/0092-8674(79)90290-3  0.667
1979 Moran L, Mirault ME, Tissières A, Lis J, Schedl P, Artavanis-Tsakonas S, Gehring WJ. Physical map of two D. melanogaster DNA segments containing sequences coding for the 70,000 dalton heat shock protein. Cell. 17: 1-8. PMID 110458 DOI: 10.1016/0092-8674(79)90289-7  0.705
1978 Weideli H, Schedl P, Artavanis-Tsakonas S, Steward R, Yuan R, Gehring WJ. Purification of a protein from unfertilized eggs of Drosophila with specific affinity for a defined DNA sequence and the cloning of this DNA sequence in bacterial plasmids. Cold Spring Harbor Symposia On Quantitative Biology. 42: 693-700. PMID 209934 DOI: 10.1101/Sqb.1978.042.01.071  0.632
1978 Schedl P, Artavanis-Tsakonas S, Steward R, Gehring WJ, Mirault ME, Goldschmidt-Clermont M, Moran L, Tissières A. Two hybrid plasmids with D. melanogaster DNA sequences complementary to mRNA coding for the major heat shock protein. Cell. 14: 921-9. PMID 99246 DOI: 10.1016/0092-8674(78)90346-X  0.599
1977 Artavanis-Tsakonas S, Schedl P, Tschudi C, Pirrotta V, Steward R, Gehring WJ. The 5S genes of Drosophila melanogaster. Cell. 12: 1057-67. PMID 413625 DOI: 10.1016/0092-8674(77)90169-6  0.654
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