Richard G. MacDonald - Publications

Affiliations: 
University of Nebraska Medical Center, Omaha, NE, United States 
Area:
Biochemistry

71 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Fei X, Zavorka ME, Malik G, Connelly CM, MacDonald RG, Berkowitz DB. General Linker Diversification Approach to Bivalent Ligand Assembly: Generation of an Array of Ligands for the Cation-Independent Mannose 6-Phosphate Receptor. Organic Letters. PMID 28753028 DOI: 10.1021/Acs.Orglett.7B01914  0.698
2017 Guo L, Costanzo-Garvey DL, Smith DR, Neilsen BK, MacDonald RG, Lewis RE. Kinase Suppressor of Ras 2 (KSR2) expression in the brain regulates energy balance and glucose homeostasis. Molecular Metabolism. 6: 194-205. PMID 28180061 DOI: 10.1016/J.Molmet.2016.12.004  0.498
2016 Zavorka ME, Connelly CM, Grosely R, MacDonald RG. Inhibition of insulin-like growth factor II (IGF-II)-dependent cell growth by multidentate pentamannosyl 6-phosphate-based ligands targeting the mannose 6-phosphate/IGF-II receptor. Oncotarget. 62386-62410. PMID 27694693 DOI: 10.18632/oncotarget.11493  0.776
2016 Zavorka ME, Connelly CM, Grosely R, MacDonald RG. Inhibition of insulin-like growth factor II (IGF-II)-dependent cell growth by multidentate pentamannosyl 6-phosphate-based ligands targeting the mannose 6-phosphate/IGF-II receptor. Oncotarget. 7: 62386-62410. PMID 27694692 DOI: 10.18632/Oncotarget.11493  0.789
2016 Guo L, Costanzo-Garvey DL, Smith DR, Zavorka ME, Venable-Kang M, MacDonald RG, Lewis RE. Cell non-autonomous regulation of hepatic IGF-1 and neonatal growth by Kinase Suppressor of Ras 2 (KSR2). Scientific Reports. 6: 32093. PMID 27561547 DOI: 10.1038/Srep32093  0.514
2016 Wang Y, MacDonald RG, Thinakaran G, Kar S. Insulin-Like Growth Factor-II/Cation-Independent Mannose 6-Phosphate Receptor in Neurodegenerative Diseases. Molecular Neurobiology. PMID 26993302 DOI: 10.1007/S12035-016-9849-7  0.535
2015 Wang Y, Buggia-Prévot V, Zavorka ME, Bleackley RC, MacDonald RG, Thinakaran G, Kar S. Overexpression of the Insulin-Like Growth Factor II Receptor Increases β-Amyloid Production and Affects Cell Viability. Molecular and Cellular Biology. 35: 2368-84. PMID 25939386 DOI: 10.1128/Mcb.01338-14  0.495
2012 Amritraj A, Posse de Chaves EI, Hawkes C, Macdonald RG, Kar S. Single-transmembrane domain IGF-II/M6P receptor: potential interaction with G protein and its association with cholesterol-rich membrane domains. Endocrinology. 153: 4784-98. PMID 22903618 DOI: 10.1210/En.2012-1139  0.538
2012 Peters HL, Tuli A, Wang X, Liu C, Pan Z, Ouellette MM, Hollingsworth MA, Macdonald RG, Solheim JC. Relevance of amyloid precursor-like protein 2 C-terminal fragments in pancreatic cancer cells. International Journal of Oncology. 41: 1464-74. PMID 22797723 DOI: 10.3892/Ijo.2012.1553  0.329
2012 Kreiling JL, Montgomery MA, Wheeler JR, Kopanic JL, Connelly CM, Zavorka ME, Allison JL, Macdonald RG. Dominant-negative effect of truncated mannose 6-phosphate/insulin-like growth factor II receptor species in cancer. The Febs Journal. 279: 2695-713. PMID 22681933 DOI: 10.1111/J.1742-4658.2012.08652.X  0.778
2011 Peters HL, Tuli A, Sharma M, Naslavsky N, Caplan S, MacDonald RG, Solheim JC. Regulation of major histocompatibility complex class I molecule expression on cancer cells by amyloid precursor-like protein 2. Immunologic Research. 51: 39-44. PMID 21826533 DOI: 10.1007/S12026-011-8238-6  0.312
2009 Hartman MA, Kreiling JL, Byrd JC, MacDonald RG. High-affinity ligand binding by wild-type/mutant heteromeric complexes of the mannose 6-phosphate/insulin-like growth factor II receptor. The Febs Journal. 276: 1915-29. PMID 19236480 DOI: 10.1111/J.1742-4658.2009.06917.X  0.82
2008 Fei X, Connelly CM, MacDonald RG, Berkowitz DB. A set of phosphatase-inert "molecular rulers" to probe for bivalent mannose 6-phosphate ligand-receptor interactions. Bioorganic & Medicinal Chemistry Letters. 18: 3085-9. PMID 18068981 DOI: 10.1016/J.Bmcl.2007.11.094  0.713
2007 Hawkes C, Amritraj A, MacDonald RG, Jhamandas JH, Kar S. Heterotrimeric G proteins and the single-transmembrane domain IGF-II/M6P receptor: Functional interaction and relevance to cell signaling Molecular Neurobiology. 35: 329-345. PMID 17917122 DOI: 10.1007/S12035-007-0021-2  0.478
2006 Hawkes C, Jhamandas JH, Harris KH, Fu W, MacDonald RG, Kar S. Single transmembrane domain insulin-like growth factor-II/mannose-6-phosphate receptor regulates central cholinergic function by activating a G-protein-sensitive, protein kinase C-dependent pathway. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 585-96. PMID 16407557 DOI: 10.1523/Jneurosci.2730-05.2006  0.55
2005 Kreiling JL, Byrd JC, MacDonald RG. Domain interactions of the mannose 6-phosphate/insulin-like growth factor II receptor. The Journal of Biological Chemistry. 280: 21067-77. PMID 15799974 DOI: 10.1074/Jbc.M412971200  0.8
2004 Berkowitz DB, Maiti G, Charette BD, Dreis CD, MacDonald RG. Mono- and bivalent ligands bearing mannose 6-phosphate (M6P) surrogates: targeting the M6P/insulin-like growth factor II receptor. Organic Letters. 6: 4921-4. PMID 15606100 DOI: 10.1021/Ol0479444  0.559
2003 Macdonald RG, Byrd JC. The insulin-like growth factor II/mannose 6-phosphate receptor: implications for IGF action in breast cancer. Breast Disease. 17: 61-72. PMID 15687678 DOI: 10.3233/Bd-2003-17107  0.565
2003 Kreiling JL, Byrd JC, Deisz RJ, Mizukami IF, Todd RF, MacDonald RG. Binding of urokinase-type plasminogen activator receptor (uPAR) to the mannose 6-phosphate/insulin-like growth factor II receptor: contrasting interactions of full-length and soluble forms of uPAR. The Journal of Biological Chemistry. 278: 20628-37. PMID 12665524 DOI: 10.1074/Jbc.M302249200  0.794
2003 Schaffer BS, Lin MF, Byrd JC, Park JH, MacDonald RG. Opposing roles for the insulin-like growth factor (IGF)-II and mannose 6-phosphate (Man-6-P) binding activities of the IGF-II/Man-6-P receptor in the growth of prostate cancer cells. Endocrinology. 144: 955-66. PMID 12586773 DOI: 10.1210/En.2002-220751  0.773
2003 Haorah J, MacDonald RG, Stoner JA, Donohue TM. Ethanol consumption decreases the synthesis of the mannose 6-phosphate/insulin-like growth factor II receptor but does not decrease its messenger RNA. Biochemical Pharmacology. 65: 637-48. PMID 12566093 DOI: 10.1016/S0006-2952(02)01605-2  0.423
2002 Corkins MR, McQuade J, Schaffer BS, MacDonald RG. Insulin-like growth factor binding protein-4 expression is dependent on the carbohydrate in the media in HT-29 cells. Growth Hormone & Igf Research : Official Journal of the Growth Hormone Research Society and the International Igf Research Society. 12: 184-92. PMID 12163000 DOI: 10.1016/S1096-6374(02)00041-2  0.755
2002 Kim EJ, Schaffer BS, Kang YH, Macdonald RG, Park JH. Decreased production of insulin-like growth factor-binding protein (IGFBP)-6 by transfection of colon cancer cells with an antisense IGFBP-6 cDNA construct leads to stimulation of cell proliferation. Journal of Gastroenterology and Hepatology. 17: 563-70. PMID 12084030 DOI: 10.1046/J.1440-1746.2002.02703.X  0.761
2002 Haorah J, McVicker DL, Byrd JC, MacDonald RG, Donohue TM. Chronic ethanol administration decreases the ligand binding properties and the cellular content of the mannose 6-phosphate/insulin-like growth factor II receptor in rat hepatocytes. Biochemical Pharmacology. 63: 1229-39. PMID 11960599 DOI: 10.1016/S0006-2952(02)00877-8  0.458
2002 Kim EJ, Kang YH, Schaffer BS, Bach LA, MacDonald RG, Park JH. Inhibition of Caco-2 cell proliferation by all-trans retinoic acid: role of insulin-like growth factor binding protein-6. Journal of Cellular Physiology. 190: 92-100. PMID 11807815 DOI: 10.1002/Jcp.10045  0.77
2002 Haorah J, McVicker DL, Byrd JC, MacDonald RG, Donohue TM. Erratum: Chronic ethanol administration decreases the ligand binding properties and the cellular content of the mannose 6-phosphate/insulin-like growth factor II receptor in rat hepatocytes (Biochemical Pharmacology (2002) 63 (1229-1239) PII: S0006295202008778) Biochemical Pharmacology. 64: 551. DOI: 10.1016/S0006-2952(02)01266-2  0.537
2001 Oh YS, Kim EJ, Schaffer BS, Kang YH, Binderup L, MacDonald RG, Park JH. Synthetic low-calcaemic vitamin D(3) analogues inhibit secretion of insulin-like growth factor II and stimulate production of insulin-like growth factor-binding protein-6 in conjunction with growth suppression of HT-29 colon cancer cells. Molecular and Cellular Endocrinology. 183: 141-9. PMID 11604234 DOI: 10.1016/S0303-7207(01)00598-6  0.749
2000 Killian JK, Byrd JC, Jirtle JV, Munday BL, Stoskopf MK, MacDonald RG, Jirtle RL. M6P/IGF2R imprinting evolution in mammals Molecular Cell. 5: 707-716. PMID 10882106 DOI: 10.1016/S1097-2765(00)80249-X  0.462
2000 Byrd JC, Park JH, Schaffer BS, Garmroudi F, MacDonald RG. Dimerization of the insulin-like growth factor II/mannose 6-phosphate receptor. The Journal of Biological Chemistry. 275: 18647-56. PMID 10764761 DOI: 10.1074/Jbc.M001273200  0.776
2000 Byrd JC, MacDonald RG. Mechanisms for high affinity mannose 6-phosphate ligand binding to the insulin-like growth factor II/mannose 6-phosphate receptor. Negative cooperativity and receptor oligomerization Journal of Biological Chemistry. 275: 18638-18646. PMID 10764735 DOI: 10.1074/Jbc.M000010200  0.526
2000 Corkins MR, Schaffer BS, MacDonald RG. Retinoic acid decreases expression of insulin-like growth factor (IFG)-II by HT-29 cells Gastroenterology. 118: A1065. DOI: 10.1016/S0016-5085(00)80054-2  0.744
1999 Corkins MR, Park JHY, Davis DV, Slentz DH, MacDonald RG. Regulation of the insulin-like growth factor axis by increasing cell number in intestinal epithelial (IEC-6) cells Growth Hormone and Igf Research. 9: 414-424. PMID 10629161 DOI: 10.1054/Ghir.1999.0119  0.534
1999 Devi GR, De Souza AT, Byrd JC, Jirtle RL, MacDonald RG. Altered ligand binding by insulin-like growth factor II/mannose 6- phosphate receptors bearing missense mutations in human cancers Cancer Research. 59: 4314-4319. PMID 10485478  0.518
1999 Byrd JC, Devi GR, De Souza AT, Jirtle RL, MacDonald RG. Disruption of ligand binding to the insulin-like growth factor II/mannose 6-phosphate receptor by cancer-associated missense mutations Journal of Biological Chemistry. 274: 24408-24416. PMID 10446221 DOI: 10.1074/Jbc.274.34.24408  0.589
1999 MacDonald RG, Schaffer BS, Kang IJ, Hong SM, Kim EJ, Park JH. Growth inhibition and differentiation of the human colon carcinoma cell line, Caco-2, by constitutive expression of insulin-like growth factor binding protein-3. Journal of Gastroenterology and Hepatology. 14: 72-8. PMID 10029281 DOI: 10.1046/J.1440-1746.1999.01803.X  0.753
1998 Corkins MR, Kaufman SS, Vanderhoof JA, Milazzo Y, Holtz G, MacDonald RG, Langnas A. Transplanted small bowel and expression of the insulin-like growth factor binding proteins Pediatric Transplantation. 2: 206-210. PMID 10084744 DOI: 10.1097/00005176-199805000-00028  0.441
1998 Devi GR, Byrd JC, Slentz DH, MacDonald RG. An insulin-like growth factor II (IGF-II) affinity-enhancing domain localized within extracytoplasmic repeat 13 of the IGF-II/Mannose 6-phosphate receptor Molecular Endocrinology. 12: 1661-1672. PMID 9817593 DOI: 10.1210/Mend.12.11.0192  0.59
1998 MacDonald RG, McCusker RH, Blackwood DJ, Vanderhoof JA, Park JHY. Production of insulin-like growth factor I (IGF-I) and IGF-binding proteins by rat intestinal stromal cells in vitro Cellular and Molecular Life Sciences. 54: 158-166. PMID 9539958 DOI: 10.1007/S000180050137  0.491
1998 Corkins MR, Schaffer BS, MacDonald RG. INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN (IGFBP)-4 EXPRESSION IN HT-29 CELLS IS DEPENDENT ON THE CARBOHYDRATE AVAILABLE IN CULTURE MEDIUM Journal of Pediatric Gastroenterology & Nutrition. 27: 474. DOI: 10.1097/00005176-199810000-00065  0.755
1996 Garmroudi F, Devi G, Slentz DH, Schaffer BS, MacDonald RG. Truncated forms of the insulin-like growth factor II (IGF-II)/mannose 6-phosphate receptor encompassing the IGF-II binding site: characterization of a point mutation that abolishes IGF-II binding. Molecular Endocrinology (Baltimore, Md.). 10: 642-51. PMID 8776724 DOI: 10.1210/Mend.10.6.8776724  0.796
1996 Park JH, Corkins MR, Vanderhoof JA, Caruso NM, Hrbek MJ, Schaffer BS, Slentz DH, McCusker RH, MacDonald RG. Expression of insulin-like growth factor-II and insulin-like growth factor binding proteins during Caco-2 cell proliferation and differentiation. Journal of Cellular Physiology. 166: 396-406. PMID 8592000 DOI: 10.1002/(Sici)1097-4652(199602)166:2<396::Aid-Jcp18>3.0.Co;2-9  0.769
1995 Gilchrist CA, Park JHY, MacDonald RG, Shull JD. Estradiol and triiodothyronine increase production of insulin-like growth factor-I (IGF-I) and insulin-like growth factor binding protein-3 (IGFBP-3) by GH4C1 rat pituitary tumor cells Molecular and Cellular Endocrinology. 114: 147-156. PMID 8674839 DOI: 10.1016/0303-7207(95)03654-P  0.442
1995 Sullivan TA, MacDonald RG. Distribution of insulin-like growth factor receptors in rat intestinal epithelium The Nebraska Medical Journal. 80: 58-61. PMID 7731482  0.443
1995 Corkins MR, Vanderhoof JA, Slentz DH, Macdonald RG, Park JHY. Growth Stimulation by Transfection of Intestinal Epithelial Cells with an Antisense Insulin-like Growth Factor-Binding Protein-2 Construct Biochemical and Biophysical Research Communications. 211: 707-713. PMID 7541197 DOI: 10.1006/Bbrc.1995.1870  0.534
1995 Corkins MR, Vanderhoof JA, Slentz DH, MacDonald RG, Hollingsworth MA, k M. OVEREXPRESSION OF INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN (IGFBP)-4 RESULTS IN INCREASED PROLIFERATION RATE AND MUC3 EXPRESSION Journal of Pediatric Gastroenterology and Nutrition. 21: 346. DOI: 10.1097/00005176-199510000-00099  0.521
1994 Garmroudi F, MacDonald RG. Localization of the insulin-like growth factor II (IGF-II) binding/cross-linking site of the IGF-II/mannose 6-phosphate receptor to extracellular repeats 10-11 Journal of Biological Chemistry. 269: 26944-26952. PMID 7929433  0.463
1994 Zhu J, Toews ML, MacDonald RG, Hexum TD. Neuropeptide Y promotes GTP photo-incorporation into a 55 kDa protein. European Journal of Pharmacology. 268: 279-91. PMID 7805755 DOI: 10.1016/0922-4106(94)90052-3  0.304
1994 Corkins MR, Vanderhoof JA, Caruso RM, Slentz DH, MacDonald RG, Park JH. 10 STIMULATION OF CELL PROLIFERATION BY EXPRESSION OF A REVERSE INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN-2 (IGFBP-2) CONSTRUCT IN INTESTINAL EPITHELIAL CELLS (IEC-6) Journal of Pediatric Gastroenterology and Nutrition. 19: 331. DOI: 10.1097/00005176-199410000-00022  0.521
1992 Park JHY, McCusker RH, Vanderhoof JA, Mohammadpour H, Harty RF, MacDonald RG. Secretion of insulin-like growth factor II (IGF-II) and IGF-binding protein-2 by intestinal epithelial (IEC-6) cells: Implications for autocrine growth regulation Endocrinology. 131: 1359-1368. PMID 1380441 DOI: 10.1210/Endo.131.3.1380441  0.578
1992 Li W, MacDonald RG, Hexum TD. Role of sulfhydryl groups in Y2 neuropeptide Y receptor binding activity. The Journal of Biological Chemistry. 267: 7570-5. PMID 1348506  0.311
1992 Li W, MacDonald RG, Hexum TD. Neuropeptide Y receptor in bovine hippocampus is a Y2 receptor. Life Sciences. 50: 695-703. PMID 1310789 DOI: 10.1016/0024-3205(92)90472-2  0.412
1991 Macdonald RG. Mannose-6-phosphate enhances cross-linking efficiency between insulin-like growth factor-II (IGF-II) and IGF-II/mannose-6-phosphate receptors in membranes Endocrinology. 128: 413-421. PMID 1846107 DOI: 10.1210/Endo-128-1-413  0.57
1990 Crisá L, Greiner DL, Mordes JP, MacDonald RG, Handler ES, Czech MP, Rossini AA. Biochemical studies of RT6 alloantigens in BB/wor and normal rats: Evidence for intact unexpressed RT6a structural gene in diabetes-prone BB rats Diabetes. 39: 1279-1288. PMID 2210079 DOI: 10.2337/Diab.39.10.1279  0.424
1990 Park JHY, Vanderhoof JA, Blackwood D, Macdonald RG. Characterization of type I and type II insulin-like growth factor receptors in an intestinal epithelial cell line Endocrinology. 126: 2998-3005. PMID 2161743 DOI: 10.1210/Endo-126-6-2998  0.577
1990 Lewis RE, Wu GP, MacDonald RG, Czech MP. Insulin-sensitive phosphorylation of serine 1293/1294 on the human insulin receptor by a tightly associated serine kinase Journal of Biological Chemistry. 265: 947-954. PMID 2136851  0.365
1989 MacDonald RG, Tepper MA, Clairmont KB, Perregaux SB, Czech MP. Serum form of the rat insulin-like growth factor II/mannose 6-phosphate receptor is truncated in the carboxyl-terminal domain Journal of Biological Chemistry. 264: 3256-3261. PMID 2536739  0.41
1989 MacDonald RG. The insulin-like growth factor II/mannose-6-phosphate receptor - IGF-II/Man-6-P receptor Cytotechnology. 2: 287-305. DOI: 10.1007/Bf00364994  0.585
1988 Macdonald RG, Pfeffer SR, Coussens L, Tepper MA, Brocklebank CM, Mole JE, Anderson JK, Chen E, Czech MP, Ullrich A. A single receptor binds both insulin-like growth factor II and mannose-6-phosphate Science. 239: 1134-1137. PMID 2964083 DOI: 10.1126/Science.2964083  0.69
1986 Czech MP, Yu KT, Lewis RE, Davis RJ, Mottola C, MacDonald RG, Necessary PC, Corvera S. Insulin receptor kinase and its mode of signaling membrane components. Diabetes/Metabolism Reviews. 1: 33-58. PMID 3013541 DOI: 10.1002/Dmr.5610010104  0.75
1986 Mottola C, MacDonald RG, Brackett JL, Mole JE, Anderson JK, Czech MP. Purification and amino-terminal sequence of an insulin-like growth factor-binding protein secreted by rat liver BRL-3A cells Journal of Biological Chemistry. 261: 11180-11188. PMID 2426267  0.415
1985 MacDonald RG, Czech MP. Biosynthesis and processing of the type II insulin-like growth factor receptor in H-35 hepatoma cells Journal of Biological Chemistry. 260: 11357-11365. PMID 2993308  0.453
1983 Okulicz WC, Boomsma RA, MacDonald RG, Leavitt WW. Conditions for the measurement of nuclear estrogen receptor at low temperature Bba - General Subjects. 757: 128-136. PMID 6838903 DOI: 10.1016/0304-4165(83)90160-5  0.355
1983 MacDonald RG, Rosenberg SP, Leavitt WW. Localization of estrogen receptor regulatory factor in the uterine nucleus Molecular and Cellular Endocrinology. 32: 301-313. PMID 6642077 DOI: 10.1016/0303-7207(83)90090-4  0.358
1983 Leavitt WW, MacDonald RG, Okulicz WC. CHAPTER 10 – Hormonal Regulation of Estrogen and Progesterone Receptor Systems Biochemical Actions of Hormones. 323-356. DOI: 10.1016/B978-0-12-452810-9.50015-2  0.32
1982 MacDonald RG, Leavitt WW. Reduced sulfhydryl groups are required for activation of uterine progesterone receptor. Possible involvement of an inhibitor of activation Journal of Biological Chemistry. 257: 311-315. PMID 7053373  0.323
1982 MacDonald RG, Okulicz WC, Leavitt WW. Progesterone-induced inactivation of nuclear estrogen receptor in the hamster uterus is mediated by acid phosphatase Biochemical and Biophysical Research Communications. 104: 570-576. PMID 6918219 DOI: 10.1016/0006-291X(82)90675-1  0.369
1981 Chen TJ, MacDonald RG, Robidoux WF, Leavitt WW. Characterization and quantification of pyridoxal 5'-phosphate-extracted nuclear progesterone receptor Journal of Steroid Biochemistry. 14: 1023-1028. PMID 7300322 DOI: 10.1016/0022-4731(81)90210-7  0.383
1981 Chen TJ, MacDonald RG, Leavitt WW. Uterine progesterone receptor: Stabilization and physicochemical alterations produced by sodium molybdate Biochemistry. 20: 3405-3411. PMID 7260046 DOI: 10.1021/Bi00515A016  0.435
1981 Okulicz WC, MacDonald RG, Leavitt WW. Progesterone-induced estrogen receptor-regulatory factor in hamster uterine nuclei: Preliminary characterization in a cell-free system Endocrinology. 109: 2273-2275. PMID 7198029 DOI: 10.1210/Endo-109-6-2273  0.384
1980 MacDonald RG, Martin TP, Cidlowski JA. Glucocorticoids stimulate protein degradation in lymphocytes: A possible mechanism of steroid-induced cell death Endocrinology. 107: 1512-1524. PMID 7428679 DOI: 10.1210/Endo-107-5-1512  0.3
1979 MacDonald RG, Cidlowski JA. Alterations in specificity of the glucocorticoid receptor with temperature in rat splenic lymphocytes Journal of Steroid Biochemistry. 10: 21-29. PMID 513714 DOI: 10.1016/0022-4731(79)90136-5  0.417
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