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A. K. McClendon, Ph.D. - Publications

Affiliations: 
2006 Vanderbilt University, Nashville, TN 
Area:
Biochemistry
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10 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2012 Dean JL, McClendon AK, Knudsen ES. Modification of the DNA damage response by therapeutic CDK4/6 inhibition. The Journal of Biological Chemistry. 287: 29075-87. PMID 22733811 DOI: 10.1074/jbc.M112.365494  0.509
2010 McClendon AK, Dean JL, Ertel A, Knudsen ES. Differential impact of tumor suppressor pathways on DNA damage response and therapy-induced transformation in a mouse primary cell model. Plos One. 5: e8558. PMID 20049321 DOI: 10.1371/journal.pone.0008558  0.303
2008 McClendon AK, Gentry AC, Dickey JS, Brinch M, Bendsen S, Andersen AH, Osheroff N. Bimodal recognition of DNA geometry by human topoisomerase II alpha: preferential relaxation of positively supercoiled DNA requires elements in the C-terminal domain. Biochemistry. 47: 13169-78. PMID 19053267 DOI: 10.1021/Bi800453H  0.596
2008 Braden WA, McClendon AK, Knudsen ES. Cyclin-dependent kinase 4/6 activity is a critical determinant of pre-replication complex assembly. Oncogene. 27: 7083-93. PMID 18776921 DOI: 10.1038/onc.2008.319  0.329
2007 Frøhlich RF, Veigaard C, Andersen FF, McClendon AK, Gentry AC, Andersen AH, Osheroff N, Stevnsner T, Knudsen BR. Tryptophane-205 of human topoisomerase I is essential for camptothecin inhibition of negative but not positive supercoil removal. Nucleic Acids Research. 35: 6170-80. PMID 17827209 DOI: 10.1093/Nar/Gkm669  0.684
2007 McClendon AK, Osheroff N. DNA topoisomerase II, genotoxicity, and cancer. Mutation Research. 623: 83-97. PMID 17681352 DOI: 10.1016/J.Mrfmmm.2007.06.009  0.738
2006 McClendon AK, Dickey JS, Osheroff N. Ability of viral topoisomerase II to discern the handedness of supercoiled DNA: bimodal recognition of DNA geometry by type II enzymes. Biochemistry. 45: 11674-80. PMID 16981727 DOI: 10.1021/Bi0520838  0.74
2006 McClendon AK, Osheroff N. The geometry of DNA supercoils modulates topoisomerase-mediated DNA cleavage and enzyme response to anticancer drugs. Biochemistry. 45: 3040-50. PMID 16503659 DOI: 10.1021/Bi051987Q  0.756
2005 McClendon AK, Rodriguez AC, Osheroff N. Human topoisomerase IIalpha rapidly relaxes positively supercoiled DNA: implications for enzyme action ahead of replication forks. The Journal of Biological Chemistry. 280: 39337-45. PMID 16188892 DOI: 10.1074/Jbc.M503320200  0.806
2004 Sappal DS, McClendon AK, Fleming JA, Thoroddsen V, Connolly K, Reimer C, Blackman RK, Bulawa CE, Osheroff N, Charlton P, Rudolph-Owen LA. Biological characterization of MLN944: a potent DNA binding agent. Molecular Cancer Therapeutics. 3: 47-58. PMID 14749475  0.643
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