| Year |
Citation |
Score |
| 2024 |
Hooks GM, Ayala JC, Holley CL, Dhulipala V, Beggs GA, Perfect JR, Schumacher MA, Shafer WM, Brennan RG. Hormonal steroids induce multidrug resistance and stress response genes in Neisseria gonorrhoeae by binding to MtrR. Nature Communications. 15: 1153. PMID 38326294 DOI: 10.1038/s41467-024-45195-1 |
0.382 |
|
| 2023 |
Hooks GM, Ayala JC, Beggs GA, Perfect JR, Schumacher MA, Shafer WM, Brennan RG. Hormonal steroids bind the multidrug resistance regulator, MtrR, to induce a multidrug binding efflux pump and stress-response sigma factor. Biorxiv : the Preprint Server For Biology. PMID 37398116 DOI: 10.1101/2023.06.13.544409 |
0.685 |
|
| 2022 |
Travis BA, Peck JV, Salinas R, Dopkins B, Lent N, Nguyen VD, Borgnia MJ, Brennan RG, Schumacher MA. Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria. Nature Communications. 13: 3793. PMID 35778410 DOI: 10.1038/s41467-022-31573-0 |
0.684 |
|
| 2021 |
Anderson BW, Schumacher MA, Yang J, Turdiev A, Turdiev H, Schroeder JW, He Q, Lee VT, Brennan RG, Wang JD. The nucleotide messenger (p)ppGpp is an anti-inducer of the purine synthesis transcription regulator PurR in Bacillus. Nucleic Acids Research. PMID 34967415 DOI: 10.1093/nar/gkab1281 |
0.627 |
|
| 2021 |
Schumacher MA, Gallagher KA, Holmes NA, Chandra G, Henderson M, Kysela DT, Brennan RG, Buttner MJ. Evolution of a σ-(c-di-GMP)-anti-σ switch. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34290147 DOI: 10.1073/pnas.2105447118 |
0.646 |
|
| 2021 |
Beggs GA, Ayala JC, Kavanaugh LG, Read TD, Hooks GM, Schumacher MA, Shafer WM, Brennan RG. Structures of Neisseria gonorrhoeae MtrR-operator complexes reveal molecular mechanisms of DNA recognition and antibiotic resistance-conferring clinical mutations. Nucleic Acids Research. PMID 33784401 DOI: 10.1093/nar/gkab213 |
0.64 |
|
| 2020 |
Travis BA, Ramsey KM, Prezioso SM, Tallo T, Wandzilak JM, Hsu A, Borgnia M, Bartesaghi A, Dove SL, Brennan RG, Schumacher MA. Structural Basis for Virulence Activation of Francisella tularensis. Molecular Cell. PMID 33217319 DOI: 10.1016/j.molcel.2020.10.035 |
0.667 |
|
| 2020 |
Arshad M, Beggs GA, Brennan RG, Seed PC. Optimization of a non-canonical anti-infective: Interrogation of the target binding pocket for a small molecule inhibitor of polysaccharide capsule expression. Antimicrobial Agents and Chemotherapy. PMID 33077659 DOI: 10.1128/AAC.01208-20 |
0.411 |
|
| 2020 |
Orans J, Kovach AR, Hoff KE, Horstmann NM, Brennan RG. Crystal structure of an Escherichia coli Hfq Core (residues 2-69)-DNA complex reveals multifunctional nucleic acid binding sites. Nucleic Acids Research. PMID 32133526 DOI: 10.1093/Nar/Gkaa149 |
0.818 |
|
| 2020 |
Dorman CJ, Schumacher MA, Bush MJ, Brennan RG, Buttner MJ. When is a transcription factor a NAP? Current Opinion in Microbiology. 55: 26-33. PMID 32120333 DOI: 10.1016/J.Mib.2020.01.019 |
0.649 |
|
| 2019 |
Gibbs KD, Washington EJ, Jaslow SL, Bourgeois JS, Foster MW, Guo R, Brennan RG, Ko DC. The Salmonella Secreted Effector SarA/SteE Mimics Cytokine Receptor Signaling to Activate STAT3. Cell Host & Microbe. PMID 31901521 DOI: 10.1016/J.Chom.2019.11.012 |
0.335 |
|
| 2019 |
Gallagher KA, Schumacher MA, Bush MJ, Bibb MJ, Chandra G, Holmes NA, Zeng W, Henderson M, Zhang H, Findlay KC, Brennan RG, Buttner MJ. c-di-GMP Arms an Anti-σ to Control Progression of Multicellular Differentiation in Streptomyces. Molecular Cell. PMID 31810759 DOI: 10.1016/J.Molcel.2019.11.006 |
0.623 |
|
| 2019 |
Beggs GA, Brennan RG, Arshad M. MarR family proteins are important regulators of clinically relevant antibiotic resistance. Protein Science : a Publication of the Protein Society. PMID 31682303 DOI: 10.1002/Pro.3769 |
0.34 |
|
| 2019 |
Beggs GA, Zalucki YM, Brown NG, Rastegari S, Phillips RK, Palzkill T, Shafer W, Kumaraswami M, Brennan RG. Structural, biochemical and characterization of MtrR-mediated resistance to innate antimicrobials by the human pathogen . Journal of Bacteriology. PMID 31331979 DOI: 10.1128/Jb.00401-19 |
0.451 |
|
| 2018 |
Schumacher MA, den Hengst CD, Bush MJ, Le TBK, Tran NT, Chandra G, Zeng W, Travis B, Brennan RG, Buttner MJ. The MerR-like protein BldC binds DNA direct repeats as cooperative multimers to regulate Streptomyces development. Nature Communications. 9: 1139. PMID 29556010 DOI: 10.1038/s41467-018-03576-3 |
0.72 |
|
| 2017 |
Cuthbert BJ, Ross W, Rohlfing AE, Dove SL, Gourse RL, Brennan RG, Schumacher MA. Dissection of the molecular circuitry controlling virulence in Francisella tularensis. Genes & Development. PMID 28864445 DOI: 10.1101/Gad.303701.117 |
0.687 |
|
| 2017 |
Miao Y, Tenor JL, Toffaletti DL, Maskarinec SA, Liu J, Lee RE, Perfect JR, Brennan RG. Structural and In Vivo Studies on Trehalose-6-Phosphate Synthase from Pathogenic Fungi Provide Insights into Its Catalytic Mechanism, Biological Necessity, and Potential for Novel Antifungal Drug Design. Mbio. 8. PMID 28743811 DOI: 10.1128/Mbio.00643-17 |
0.42 |
|
| 2017 |
Schumacher MA, Zeng W, Findlay KC, Buttner MJ, Brennan RG, Tschowri N. The Streptomyces master regulator BldD binds c-di-GMP sequentially to create a functional BldD2-(c-di-GMP)4 complex. Nucleic Acids Research. PMID 28449057 DOI: 10.1093/Nar/Gkx287 |
0.649 |
|
| 2016 |
Miao Y, Tenor JL, Toffaletti DL, Washington EJ, Liu J, Shadrick WR, Schumacher MA, Lee RE, Perfect JR, Brennan RG. Structures of trehalose-6-phosphate phosphatase from pathogenic fungi reveal the mechanisms of substrate recognition and catalysis. Proceedings of the National Academy of Sciences of the United States of America. PMID 27307435 DOI: 10.1073/Pnas.1601774113 |
0.669 |
|
| 2015 |
Schumacher MA, Balani P, Min J, Chinnam NB, Hansen S, Vulić M, Lewis K, Brennan RG. HipBA-promoter structures reveal the basis of heritable multidrug tolerance. Nature. 524: 59-64. PMID 26222023 DOI: 10.1038/Nature14662 |
0.644 |
|
| 2015 |
Cuthbert BJ, Brennan RG, Schumacher MA. Structural and Biochemical Characterization of the Francisella tularensis Pathogenicity Regulator, Macrophage Locus Protein A (MglA). Plos One. 10: e0128225. PMID 26121147 DOI: 10.1371/Journal.Pone.0128225 |
0.704 |
|
| 2015 |
Schindler BD, Seo SM, Birukou I, Brennan RG, Kaatz GW. Mutations within the mepA operator affect binding of the MepR regulatory protein and its induction by MepA substrates in Staphylococcus aureus. Journal of Bacteriology. 197: 1104-14. PMID 25583977 DOI: 10.1128/Jb.02558-14 |
0.483 |
|
| 2015 |
Reniere ML, Whiteley AT, Hamilton KL, John SM, Lauer P, Brennan RG, Portnoy DA. Glutathione activates virulence gene expression of an intracellular pathogen. Nature. 517: 170-3. PMID 25567281 DOI: 10.1038/Nature14029 |
0.352 |
|
| 2014 |
Tschowri N, Schumacher MA, Schlimpert S, Chinnam NB, Findlay KC, Brennan RG, Buttner MJ. Tetrameric c-di-GMP mediates effective transcription factor dimerization to control Streptomyces development. Cell. 158: 1136-47. PMID 25171413 DOI: 10.1016/J.Cell.2014.07.022 |
0.63 |
|
| 2014 |
Kovach AR, Hoff KE, Canty JT, Orans J, Brennan RG. Recognition of U-rich RNA by Hfq from the Gram-positive pathogen Listeria monocytogenes. Rna (New York, N.Y.). 20: 1548-59. PMID 25150227 DOI: 10.1261/Rna.044032.113 |
0.788 |
|
| 2014 |
Birukou I, Seo SM, Schindler BD, Kaatz GW, Brennan RG. Structural mechanism of transcription regulation of the Staphylococcus aureus multidrug efflux operon mepRA by the MarR family repressor MepR. Nucleic Acids Research. 42: 2774-88. PMID 24293644 DOI: 10.1093/Nar/Gkt1215 |
0.552 |
|
| 2014 |
Robinson KE, Orans J, Kovach AR, Link TM, Brennan RG. Mapping Hfq-RNA interaction surfaces using tryptophan fluorescence quenching. Nucleic Acids Research. 42: 2736-49. PMID 24288369 DOI: 10.1093/Nar/Gkt1171 |
0.435 |
|
| 2013 |
Birukou I, Tonthat NK, Seo SM, Schindler BD, Kaatz GW, Brennan RG. The molecular mechanisms of allosteric mutations impairing MepR repressor function in multidrug-resistant strains of Staphylococcus aureus. Mbio. 4: e00528-13. PMID 23982071 DOI: 10.1128/Mbio.00528-13 |
0.522 |
|
| 2013 |
Schindler BD, Seo SM, Jacinto PL, Kumaraswami M, Birukou I, Brennan RG, Kaatz GW. Functional consequences of substitution mutations in MepR, a repressor of the Staphylococcus aureus MepA multidrug efflux pump gene. Journal of Bacteriology. 195: 3651-62. PMID 23749979 DOI: 10.1128/Jb.00565-13 |
0.433 |
|
| 2013 |
Rajagopalan S, Teter SJ, Zwart PH, Brennan RG, Phillips KJ, Kiley PJ. Studies of IscR reveal a unique mechanism for metal-dependent regulation of DNA binding specificity. Nature Structural & Molecular Biology. 20: 740-7. PMID 23644595 DOI: 10.1038/Nsmb.2568 |
0.511 |
|
| 2013 |
Birukou I, Kaatz GW, Brennan RG. Crystal Structure of a MepR-DNA Complex Reveals the Mechanism of Transcription Repression of S. Aureus Multidrug Efflux Pump mepA Biophysical Journal. 104: 256a. DOI: 10.1016/J.Bpj.2012.11.1436 |
0.586 |
|
| 2012 |
Schumacher MA, Min J, Link TM, Guan Z, Xu W, Ahn YH, Soderblom EJ, Kurie JM, Evdokimov A, Moseley MA, Lewis K, Brennan RG. Role of unusual P loop ejection and autophosphorylation in HipA-mediated persistence and multidrug tolerance. Cell Reports. 2: 518-25. PMID 22999936 DOI: 10.1016/J.Celrep.2012.08.013 |
0.628 |
|
| 2012 |
Horstmann N, Orans J, Valentin-Hansen P, Shelburne SA, Brennan RG. Structural mechanism of Staphylococcus aureus Hfq binding to an RNA A-tract. Nucleic Acids Research. 40: 11023-35. PMID 22965117 DOI: 10.1093/Nar/Gks809 |
0.469 |
|
| 2012 |
Hansen S, Vulić M, Min J, Yen TJ, Schumacher MA, Brennan RG, Lewis K. Regulation of the Escherichia coli HipBA toxin-antitoxin system by proteolysis. Plos One. 7: e39185. PMID 22720069 DOI: 10.1371/Journal.Pone.0039185 |
0.638 |
|
| 2012 |
Amato AA, Rajagopalan S, Lin JZ, Carvalho BM, Figueira AC, Lu J, Ayers SD, Mottin M, Silveira RL, Souza PC, Mourão RH, Saad MJ, Togashi M, Simeoni LA, Abdalla DS, ... ... Brennan RG, et al. GQ-16, a novel peroxisome proliferator-activated receptor γ (PPARγ) ligand, promotes insulin sensitization without weight gain. The Journal of Biological Chemistry. 287: 28169-79. PMID 22584573 DOI: 10.1074/Jbc.M111.332106 |
0.312 |
|
| 2012 |
Hansen S, VuliÄ M, Min J, Yen T, Schumacher MA, Brennan RG, Lewis K. Correction: Regulation of the Escherichia coli HipBA Toxin-Antitoxin System by Proteolysis Plos One. 7. DOI: 10.1371/Annotation/E608601C-Eadd-4C11-Adb2-7B605Aba9C44 |
0.547 |
|
| 2011 |
Horstmann N, Sahasrabhojane P, Suber B, Kumaraswami M, Olsen RJ, Flores A, Musser JM, Brennan RG, Shelburne SA. Distinct single amino acid replacements in the control of virulence regulator protein differentially impact streptococcal pathogenesis. Plos Pathogens. 7: e1002311. PMID 22028655 DOI: 10.1371/Journal.Ppat.1002311 |
0.491 |
|
| 2011 |
Le TB, Schumacher MA, Lawson DM, Brennan RG, Buttner MJ. The crystal structure of the TetR family transcriptional repressor SimR bound to DNA and the role of a flexible N-terminal extension in minor groove binding. Nucleic Acids Research. 39: 9433-47. PMID 21835774 DOI: 10.1093/Nar/Gkr640 |
0.727 |
|
| 2011 |
Shelburne SA, Sahasrobhajane P, Suber B, Keith DB, Davenport MT, Horstmann N, Kumaraswami M, Olsen RJ, Brennan RG, Musser JM. Niche-specific contribution to streptococcal virulence of a MalR-regulated carbohydrate binding protein. Molecular Microbiology. 81: 500-14. PMID 21645132 DOI: 10.1111/J.1365-2958.2011.07708.X |
0.489 |
|
| 2011 |
Peters KM, Brooks BE, Schumacher MA, Skurray RA, Brennan RG, Brown MH. A single acidic residue can guide binding site selection but does not govern QacR cationic-drug affinity. Plos One. 6: e15974. PMID 21264225 DOI: 10.1371/Journal.Pone.0015974 |
0.699 |
|
| 2011 |
Schumacher MA, Sprehe M, Bartholomae M, Hillen W, Brennan RG. Structures of carbon catabolite protein A-(HPr-Ser46-P) bound to diverse catabolite response element sites reveal the basis for high-affinity binding to degenerate DNA operators. Nucleic Acids Research. 39: 2931-42. PMID 21106498 DOI: 10.1093/Nar/Gkq1177 |
0.729 |
|
| 2010 |
Cho K, Vaught TG, Ji H, Gu D, Papasakelariou-Yared C, Horstmann N, Jennings JM, Lee M, Sevilla LM, Kloc M, Reynolds AB, Watt FM, Brennan RG, Kowalczyk AP, McCrea PD. Xenopus Kazrin interacts with ARVCF-catenin, spectrin and p190B RhoGAP, and modulates RhoA activity and epithelial integrity. Journal of Cell Science. 123: 4128-44. PMID 21062899 DOI: 10.1242/Jcs.072041 |
0.445 |
|
| 2010 |
Olsen AS, Møller-Jensen J, Brennan RG, Valentin-Hansen P. C-terminally truncated derivatives of Escherichia coli Hfq are proficient in riboregulation. Journal of Molecular Biology. 404: 173-82. PMID 20888338 DOI: 10.1016/J.Jmb.2010.09.038 |
0.365 |
|
| 2010 |
Shelburne SA, Olsen RJ, Suber B, Sahasrabhojane P, Sumby P, Brennan RG, Musser JM. A combination of independent transcriptional regulators shapes bacterial virulence gene expression during infection. Plos Pathogens. 6: e1000817. PMID 20333240 DOI: 10.1371/Journal.Ppat.1000817 |
0.334 |
|
| 2010 |
Kumaraswami M, Newberry KJ, Brennan RG. Conformational plasticity of the coiled-coil domain of BmrR is required for bmr operator binding: the structure of unliganded BmrR. Journal of Molecular Biology. 398: 264-75. PMID 20230832 DOI: 10.1016/J.Jmb.2010.03.011 |
0.577 |
|
| 2010 |
Nakano MM, Lin A, Zuber CS, Newberry KJ, Brennan RG, Zuber P. Promoter recognition by a complex of Spx and the C-terminal domain of the RNA polymerase alpha subunit. Plos One. 5: e8664. PMID 20084284 DOI: 10.1371/Journal.Pone.0008664 |
0.357 |
|
| 2009 |
Link TM, Valentin-Hansen P, Brennan RG. Structure of Escherichia coli Hfq bound to polyriboadenylate RNA. Proceedings of the National Academy of Sciences of the United States of America. 106: 19292-7. PMID 19889981 DOI: 10.1073/Pnas.0908744106 |
0.444 |
|
| 2009 |
Stoll KE, Draper WE, Kliegman JI, Golynskiy MV, Brew-Appiah RA, Phillips RK, Brown HK, Breyer WA, Jakubovics NS, Jenkinson HF, Brennan RG, Cohen SM, Glasfeld A. Characterization and structure of the manganese-responsive transcriptional regulator ScaR. Biochemistry. 48: 10308-20. PMID 19795834 DOI: 10.1021/Bi900980G |
0.808 |
|
| 2009 |
Schumacher MA, Piro KM, Xu W, Hansen S, Lewis K, Brennan RG. Molecular mechanisms of HipA-mediated multidrug tolerance and its neutralization by HipB. Science (New York, N.Y.). 323: 396-401. PMID 19150849 DOI: 10.1126/Science.1163806 |
0.691 |
|
| 2009 |
Kumaraswami M, Schuman JT, Seo SM, Kaatz GW, Brennan RG. Structural and biochemical characterization of MepR, a multidrug binding transcription regulator of the Staphylococcus aureus multidrug efflux pump MepA. Nucleic Acids Research. 37: 1211-24. PMID 19129225 DOI: 10.1093/Nar/Gkn1046 |
0.562 |
|
| 2009 |
Hassan KA, Xu Z, Watkins RE, Brennan RG, Skurray RA, Brown MH. Optimized production and analysis of the staphylococcal multidrug efflux protein QacA. Protein Expression and Purification. 64: 118-24. PMID 19073264 DOI: 10.1016/J.Pep.2008.11.009 |
0.367 |
|
| 2008 |
Newberry KJ, Huffman JL, Miller MC, Vazquez-Laslop N, Neyfakh AA, Brennan RG. Structures of BmrR-drug complexes reveal a rigid multidrug binding pocket and transcription activation through tyrosine expulsion. The Journal of Biological Chemistry. 283: 26795-804. PMID 18658145 DOI: 10.1074/Jbc.M804191200 |
0.561 |
|
| 2008 |
Peters KM, Schuman JT, Skurray RA, Brown MH, Brennan RG, Schumacher MA. QacR-cation recognition is mediated by a redundancy of residues capable of charge neutralization. Biochemistry. 47: 8122-9. PMID 18616285 DOI: 10.1021/Bi8008246 |
0.654 |
|
| 2008 |
Shelburne SA, Keith DB, Davenport MT, Horstmann N, Brennan RG, Musser JM. Molecular characterization of group A Streptococcus maltodextrin catabolism and its role in pharyngitis. Molecular Microbiology. 69: 436-52. PMID 18485073 DOI: 10.1111/J.1365-2958.2008.06290.X |
0.303 |
|
| 2008 |
Shelburne SA, Keith D, Horstmann N, Sumby P, Davenport MT, Graviss EA, Brennan RG, Musser JM. A direct link between carbohydrate utilization and virulence in the major human pathogen group A Streptococcus. Proceedings of the National Academy of Sciences of the United States of America. 105: 1698-703. PMID 18230719 DOI: 10.1073/Pnas.0711767105 |
0.317 |
|
| 2008 |
Amen M, Espinoza HM, Cox C, Liang X, Wang J, Link TM, Brennan RG, Martin JF, Amendt BA. Chromatin-associated HMG-17 is a major regulator of homeodomain transcription factor activity modulated by Wnt/beta-catenin signaling. Nucleic Acids Research. 36: 462-76. PMID 18045789 DOI: 10.1093/Nar/Gkm1047 |
0.372 |
|
| 2007 |
Newberry KJ, Fuangthong M, Panmanee W, Mongkolsuk S, Brennan RG. Structural mechanism of organic hydroperoxide induction of the transcription regulator OhrR. Molecular Cell. 28: 652-64. PMID 18042459 DOI: 10.1016/J.Molcel.2007.09.016 |
0.344 |
|
| 2007 |
Brooks BE, Piro KM, Brennan RG. Multidrug-binding transcription factor QacR binds the bivalent aromatic diamidines DB75 and DB359 in multiple positions. Journal of the American Chemical Society. 129: 8389-95. PMID 17567017 DOI: 10.1021/Ja072576V |
0.524 |
|
| 2007 |
Brennan RG, Link TM. Hfq structure, function and ligand binding. Current Opinion in Microbiology. 10: 125-33. PMID 17395525 DOI: 10.1016/J.Mib.2007.03.015 |
0.474 |
|
| 2007 |
Schumacher MA, Seidel G, Hillen W, Brennan RG. Structural mechanism for the fine-tuning of CcpA function by the small molecule effectors glucose 6-phosphate and fructose 1,6-bisphosphate. Journal of Molecular Biology. 368: 1042-50. PMID 17376479 DOI: 10.1016/J.Jmb.2007.02.054 |
0.705 |
|
| 2007 |
DeWitt MA, Kliegman JI, Helmann JD, Brennan RG, Farrens DL, Glasfeld A. The conformations of the manganese transport regulator of Bacillus subtilis in its metal-free state. Journal of Molecular Biology. 365: 1257-65. PMID 17118401 DOI: 10.1016/J.Jmb.2006.10.080 |
0.502 |
|
| 2006 |
Mattison K, Wilbur JS, So M, Brennan RG. Structure of FitAB from Neisseria gonorrhoeae bound to DNA reveals a tetramer of toxin-antitoxin heterodimers containing pin domains and ribbon-helix-helix motifs. The Journal of Biological Chemistry. 281: 37942-51. PMID 16982615 DOI: 10.1074/Jbc.M605198200 |
0.526 |
|
| 2006 |
Kliegman JI, Griner SL, Helmann JD, Brennan RG, Glasfeld A. Structural basis for the metal-selective activation of the manganese transport regulator of Bacillus subtilis. Biochemistry. 45: 3493-505. PMID 16533030 DOI: 10.1021/Bi0524215 |
0.401 |
|
| 2006 |
Schumacher MA, Seidel G, Hillen W, Brennan RG. Phosphoprotein Crh-Ser46-P displays altered binding to CcpA to effect carbon catabolite regulation. The Journal of Biological Chemistry. 281: 6793-800. PMID 16316990 DOI: 10.1074/Jbc.M509977200 |
0.664 |
|
| 2005 |
Newberry KJ, Nakano S, Zuber P, Brennan RG. Crystal structure of the Bacillus subtilis anti-alpha, global transcriptional regulator, Spx, in complex with the alpha C-terminal domain of RNA polymerase. Proceedings of the National Academy of Sciences of the United States of America. 102: 15839-44. PMID 16249335 DOI: 10.1073/Pnas.0506592102 |
0.454 |
|
| 2005 |
Hong M, Fuangthong M, Helmann JD, Brennan RG. Structure of an OhrR-ohrA operator complex reveals the DNA binding mechanism of the MarR family. Molecular Cell. 20: 131-41. PMID 16209951 DOI: 10.1016/J.Molcel.2005.09.013 |
0.546 |
|
| 2005 |
Wilbur JS, Chivers PT, Mattison K, Potter L, Brennan RG, So M. Neisseria gonorrhoeae FitA interacts with FitB to bind DNA through its ribbon-helix-helix motif. Biochemistry. 44: 12515-24. PMID 16156663 DOI: 10.1021/Bi0511080 |
0.539 |
|
| 2005 |
Hoffmann KM, Williams D, Shafer WM, Brennan RG. Characterization of the multiple transferable resistance repressor, MtrR, from Neisseria gonorrhoeae. Journal of Bacteriology. 187: 5008-12. PMID 15995218 DOI: 10.1128/Jb.187.14.5008-5012.2005 |
0.486 |
|
| 2005 |
Ramos JL, Martínez-Bueno M, Molina-Henares AJ, Terán W, Watanabe K, Zhang X, Gallegos MT, Brennan R, Tobes R. The TetR Family of Transcriptional Repressors Microbiology and Molecular Biology Reviews. 69: 326-356. PMID 15944459 DOI: 10.1128/Mmbr.69.2.326-356.2005 |
0.381 |
|
| 2004 |
Schumacher MA, Allen GS, Diel M, Seidel G, Hillen W, Brennan RG. Structural basis for allosteric control of the transcription regulator CcpA by the phosphoprotein HPr-Ser46-P. Cell. 118: 731-41. PMID 15369672 DOI: 10.1016/J.Cell.2004.08.027 |
0.683 |
|
| 2004 |
Schumacher MA, Miller MC, Brennan RG. Structural mechanism of the simultaneous binding of two drugs to a multidrug-binding protein. The Embo Journal. 23: 2923-30. PMID 15257299 DOI: 10.1038/Sj.Emboj.7600288 |
0.698 |
|
| 2004 |
Newberry KJ, Brennan RG. The structural mechanism for transcription activation by MerR family member multidrug transporter activation, N terminus. The Journal of Biological Chemistry. 279: 20356-62. PMID 14985361 DOI: 10.1074/Jbc.M400960200 |
0.517 |
|
| 2004 |
Murray DS, Schumacher MA, Brennan RG. Crystal structures of QacR-diamidine complexes reveal additional multidrug-binding modes and a novel mechanism of drug charge neutralization. The Journal of Biological Chemistry. 279: 14365-71. PMID 14726520 DOI: 10.1074/Jbc.M313870200 |
0.71 |
|
| 2004 |
Schumacher MA, Allen GS, Diel M, Seidel G, Hillen W, Brennan RG. Structural studies on the apo transcription factor form B. megaterium Cell. 118: 731-741. DOI: 10.2210/Pdb1Sxg/Pdb |
0.316 |
|
| 2003 |
Glasfeld A, Guedon E, Helmann JD, Brennan RG. Structure of the manganese-bound manganese transport regulator of Bacillus subtilis. Nature Structural Biology. 10: 652-7. PMID 12847518 DOI: 10.1038/Nsb951 |
0.456 |
|
| 2003 |
Schumacher MA, Brennan RG. Deciphering the molecular basis of multidrug recognition: crystal structures of the Staphylococcus aureus multidrug binding transcription regulator QacR. Research in Microbiology. 154: 69-77. PMID 12648720 DOI: 10.1016/S0923-2508(02)00013-X |
0.697 |
|
| 2003 |
Allen GS, Steinhauer K, Hillen W, Stülke J, Brennan RG. Crystal structure of HPr kinase/phosphatase from Mycoplasma pneumoniae Journal of Molecular Biology. 326: 1203-1217. PMID 12589763 DOI: 10.1016/S0022-2836(02)01378-5 |
0.384 |
|
| 2003 |
Glasfeld A, Guedon E, Helmann JD, Brennan RG. The structure of MntR from Bacillus subtilis Journal of Inorganic Biochemistry. 96: 71. DOI: 10.1016/S0162-0134(03)80523-8 |
0.339 |
|
| 2002 |
Godsey MH, Zheleznova Heldwein EE, Brennan RG. Structural biology of bacterial multidrug resistance gene regulators. The Journal of Biological Chemistry. 277: 40169-72. PMID 12186881 DOI: 10.1074/Jbc.R200018200 |
0.322 |
|
| 2002 |
Schumacher MA, Brennan RG. Structural mechanisms of multidrug recognition and regulation by bacterial multidrug transcription factors. Molecular Microbiology. 45: 885-93. PMID 12180910 DOI: 10.1046/J.1365-2958.2002.03039.X |
0.696 |
|
| 2002 |
Schumacher MA, Pearson RF, Møller T, Valentin-Hansen P, Brennan RG. Structures of the pleiotropic translational regulator Hfq and an Hfq-RNA complex: a bacterial Sm-like protein. The Embo Journal. 21: 3546-56. PMID 12093755 DOI: 10.1093/Emboj/Cdf322 |
0.693 |
|
| 2002 |
Bashor C, Denu JM, Brennan RG, Ullman B. Kinetic mechanism of adenine phosphoribosyltransferase from Leishmania donovani. Biochemistry. 41: 4020-31. PMID 11900545 DOI: 10.1021/Bi0158730 |
0.365 |
|
| 2002 |
Schumacher MA, Miller MC, Grkovic S, Brown MH, Skurray RA, Brennan RG. Structural basis for cooperative DNA binding by two dimers of the multidrug-binding protein QacR. The Embo Journal. 21: 1210-8. PMID 11867549 DOI: 10.1093/Emboj/21.5.1210 |
0.751 |
|
| 2002 |
Steinhauer K, Allen GS, Hillen W, Stülke J, Brennan RG. Crystallization, preliminary X-ray analysis and biophysical characterization of HPr kinase/phosphatase of Mycoplasma pneumoniae Acta Crystallographica Section D: Biological Crystallography. 58: 515-518. PMID 11856840 DOI: 10.1107/S090744490102145X |
0.357 |
|
| 2002 |
Huffman JL, Brennan RG. Prokaryotic transcription regulators: more than just the helix-turn-helix motif. Current Opinion in Structural Biology. 12: 98-106. PMID 11839496 DOI: 10.1016/S0959-440X(02)00295-6 |
0.545 |
|
| 2002 |
Møller T, Franch T, Højrup P, Keene DR, Bächinger HP, Brennan RG, Valentin-Hansen P. Hfq: a bacterial Sm-like protein that mediates RNA-RNA interaction. Molecular Cell. 9: 23-30. PMID 11804583 DOI: 10.1016/S1097-2765(01)00436-1 |
0.318 |
|
| 2002 |
Huffman JL, Lu F, Zalkin H, Brennan RG. Role of residue 147 in the gene regulatory function of the Escherichia coli purine repressor. Biochemistry. 41: 511-20. PMID 11781089 DOI: 10.1021/Bi0156660 |
0.501 |
|
| 2002 |
Schumacher MA, Bashor CJ, Song MH, Otsu K, Zhu S, Parry RJ, Ullman B, Brennan RG. The structural mechanism of GTP stabilized oligomerization and catalytic activation of the Toxoplasma gondii uracil phosphoribosyltransferase. Proceedings of the National Academy of Sciences of the United States of America. 99: 78-83. PMID 11773618 DOI: 10.1073/Pnas.012399599 |
0.661 |
|
| 2002 |
Hoffmann KM, Schumacher MA, Brennan RG. Indirect readout of the PurF operator by the purine repressor (PurR) Acta Crystallographica Section a Foundations of Crystallography. 58: c139-c139. DOI: 10.1107/S0108767302090578 |
0.494 |
|
| 2001 |
Schumacher MA, Miller MC, Grkovic S, Brown MH, Skurray RA, Brennan RG. Structural mechanisms of QacR induction and multidrug recognition. Science (New York, N.Y.). 294: 2158-63. PMID 11739955 DOI: 10.1126/Science.1066020 |
0.707 |
|
| 2001 |
Grkovic S, Brown MH, Schumacher MA, Brennan RG, Skurray RA. The staphylococcal QacR multidrug regulator binds a correctly spaced operator as a pair of dimers. Journal of Bacteriology. 183: 7102-9. PMID 11717268 DOI: 10.1128/Jb.183.24.7102-7109.2001 |
0.709 |
|
| 2001 |
Godsey MH, Baranova NN, Neyfakh AA, Brennan RG. Crystal structure of MtaN, a global multidrug transporter gene activator. The Journal of Biological Chemistry. 276: 47178-84. PMID 11581256 DOI: 10.1074/Jbc.M105819200 |
0.467 |
|
| 2001 |
Huffman JL, Mokashi A, Bächinger HP, Brennan RG. The basic helix-loop-helix domain of the aryl hydrocarbon receptor nuclear transporter (ARNT) can oligomerize and bind E-box DNA specifically. The Journal of Biological Chemistry. 276: 40537-44. PMID 11502749 DOI: 10.1074/Jbc.M105675200 |
0.465 |
|
| 2001 |
Zheleznova Heldwein EE, Brennan RG. Crystal structure of the transcription activator BmrR bound to DNA and a drug Nature. 409: 378-382. PMID 11201751 DOI: 10.1038/35053138 |
0.508 |
|
| 2001 |
Schumacher MA, Hurlburt BK, Brennan RG. Crystal structures of SarA, a pleiotropic regulator of virulence genes in S. aureus Nature. 409: 215-219. PMID 11196648 DOI: 10.1038/35051623 |
0.728 |
|
| 2001 |
Craig JC, Schumacher MA, Mansoor SE, Farrens DL, Brennan RG, Goodman RH. Consensus and variant cAMP-regulated enhancers have distinct CREB-binding properties. The Journal of Biological Chemistry. 276: 11719-28. PMID 11134034 DOI: 10.1074/Jbc.M010263200 |
0.536 |
|
| 2001 |
Schumacher MA, Hurlburt BK, Brennan RG. Erratum: correction: Crystal structures of SarA, a pleiotropic regulator of virulence genes in S. aureus Nature. 414: 85-85. DOI: 10.1038/35102089 |
0.648 |
|
| 2000 |
Godsey MH, Baranova NN, Neyfakh AA, Brennan RG. Crystallization and preliminary X-ray diffraction studies on the DNA-binding domain of the multidrug transporter activation protein (MtaN) from Bacillus subtilis. Acta Crystallographica. Section D, Biological Crystallography. 56: 1456-8. PMID 11053850 DOI: 10.1107/S0907444900010295 |
0.437 |
|
| 2000 |
Zheleznova EE, Crosa JH, Brennan RG. Characterization of the DNA- and metal-binding properties of Vibrio anguillarum Fur reveals conservation of a structural Zn2+ ion Journal of Bacteriology. 182: 6264-6267. PMID 11029454 DOI: 10.1128/Jb.182.21.6264-6267.2000 |
0.413 |
|
| 2000 |
Vazquez-Laslop N, Zheleznovat EE, Markham PN, Brennan RG, Neyfakh AA. Recognition of multiple drugs by a single protein: A trivial solution of an old paradox Biochemical Society Transactions. 28: 517-520. PMID 10961951 DOI: 10.1042/Bst0280517 |
0.492 |
|
| 2000 |
Schumacher MA, Goodman RH, Brennan RG. The structure of a CREB bZIP.somatostatin CRE complex reveals the basis for selective dimerization and divalent cation-enhanced DNA binding. The Journal of Biological Chemistry. 275: 35242-7. PMID 10952992 DOI: 10.1074/Jbc.M007293200 |
0.715 |
|
| 2000 |
Brown M, Schumacher MA, Wiens GD, Brennan RG, Rittenberg MB. The structural basis of repertoire shift in an immune response to phosphocholine Journal of Experimental Medicine. 191: 2101-2111. PMID 10859335 DOI: 10.1084/Jem.191.12.2101 |
0.646 |
|
| 2000 |
Schumacher MA, Scott DM, Mathews II, Ealick SE, Roos DS, Ullman B, Brennan RG. Crystal structures of Toxoplasma gondii adenosine kinase reveal a novel catalytic mechanism and prodrug binding. Journal of Molecular Biology. 298: 875-93. PMID 10801355 DOI: 10.1006/Jmbi.2000.3753 |
0.699 |
|
| 2000 |
Cardinaux JR, Notis JC, Zhang Q, Vo N, Craig JC, Fass DM, Brennan RG, Goodman RH. Recruitment of CREB binding protein is sufficient for CREB-mediated gene activation. Molecular and Cellular Biology. 20: 1546-52. PMID 10669732 DOI: 10.1128/Mcb.20.5.1546-1552.2000 |
0.458 |
|
| 2000 |
Schumacher MA, Scott DM, Mathews II, Ealick SE, Roos DS, Ullman B, Brennan RG. Crystal structures of Toxoplasma gondii adenosine kinase reveal a novel catalytic mechanism and prodrug binding. Journal of Molecular Biology. 296: 549-67. PMID 10669608 DOI: 10.1006/Jmbi.1999.3474 |
0.699 |
|
| 2000 |
Zheleznova EE, Markham P, Edgar R, Bibi E, Neyfakh AA, Brennan RG. A structure-based mechanism for drug binding by multidrug transporters Trends in Biochemical Sciences. 25: 39-43. PMID 10664577 DOI: 10.1016/S0968-0004(99)01514-5 |
0.455 |
|
| 1999 |
Glasfeld A, Koehler AN, Schumacher MA, Brennan RG. The role of lysine 55 in determining the specificity of the purine repressor for its operators through minor groove interactions. Journal of Molecular Biology. 291: 347-61. PMID 10438625 DOI: 10.1006/Jmbi.1999.2946 |
0.701 |
|
| 1999 |
Rechtin TM, Gillaspy AF, Schumacher MA, Brennan RG, Smeltzer MS, Hurlburt BK. Characterization of the SarA virulence gene regulator of staphylococcus aureus Molecular Microbiology. 33: 307-316. PMID 10411747 DOI: 10.1046/J.1365-2958.1999.01474.X |
0.716 |
|
| 1999 |
Phillips CL, Ullman B, Brennan RG, Hill CP. Crystal structures of adenine phosphoribosyltransferase from Leishmania donovani. The Embo Journal. 18: 3533-45. PMID 10393170 DOI: 10.1093/Emboj/18.13.3533 |
0.494 |
|
| 1999 |
Zheleznova EE, Markham PN, Neyfakh AA, Brennan RG. Structural basis of multidrug recognition by BMRR, a transcription activator of a multidrug transporter Cell. 96: 353-362. PMID 10025401 DOI: 10.1016/S0092-8674(00)80548-6 |
0.503 |
|
| 1998 |
Lu F, Brennan RG, Zalkin H. Escherichia coli purine repressor: Key residues for the allosteric transition between active and inactive conformations and for interdomain signaling Biochemistry. 37: 15680-15690. PMID 9843372 DOI: 10.1021/Bi981617K |
0.509 |
|
| 1998 |
Lundblad JR, Kwok RP, Laurance ME, Huang MS, Richards JP, Brennan RG, Goodman RH. The human T-cell leukemia virus-1 transcriptional activator Tax enhances cAMP-responsive element-binding protein (CREB) binding activity through interactions with the DNA minor groove. The Journal of Biological Chemistry. 273: 19251-9. PMID 9668114 DOI: 10.1074/Jbc.273.30.19251 |
0.523 |
|
| 1998 |
Schumacher MA, Carter D, Scott DM, Roos DS, Ullman B, Brennan RG. Crystal structures of Toxoplasma gondii uracil phosphoribosyltransferase reveal the atomic basis of pyrimidine discrimination and prodrug binding. The Embo Journal. 17: 3219-32. PMID 9628859 DOI: 10.1093/Emboj/17.12.3219 |
0.672 |
|
| 1998 |
Arvidson DN, Lu F, Faber C, Zalkin H, Brennan RG. The structure of PurR mutant L54M shows an alternative to DNA kinking Nature Structural Biology. 5: 436-441. PMID 9628480 DOI: 10.1038/Nsb0698-436 |
0.511 |
|
| 1998 |
Lu F, Schumacher MA, Arvidson DN, Haldimann A, Wanner BL, Zalkin H, Brennan RG. Structure-based redesign of corepressor specificity of the Escherichia coli purine repressor by substitution of residue 190 Biochemistry. 37: 971-982. PMID 9454587 DOI: 10.1021/Bi971942S |
0.738 |
|
| 1997 |
Zheleznova EE, Markham PN, Neyfakh AA, Brennan RG. Preliminary structural studies on the multi-ligand-binding domain of the transcription activator, BmrR, from Bacillus subtilis Protein Science. 6: 2465-2468. PMID 9385651 DOI: 10.1002/Pro.5560061122 |
0.519 |
|
| 1997 |
Schumacher MA, Glasfeld A, Zalkin H, Brennan RG. The x-ray structure of the PurR-guanine-purF operator complex reveals the contributions of complementary electrostatic surfaces and a water- mediated hydrogen bond to corepressor specificity and binding affinity Journal of Biological Chemistry. 272: 22648-22653. PMID 9278422 DOI: 10.1074/Jbc.272.36.22648 |
0.739 |
|
| 1997 |
Schumacher MA, Zheleznova EE, Poundstone KS, Kluger R, Jones RT, Brennan RG. Allosteric intermediates indicate R2 is the liganded hemoglobin end state. Proceedings of the National Academy of Sciences of the United States of America. 94: 7841-4. PMID 9223274 DOI: 10.1073/Pnas.94.15.7841 |
0.567 |
|
| 1996 |
Schumacher MA, Carter D, Roos DS, Ullman B, Brennan RG. Crystal structures of Toxoplasma gondii HGXPRTase reveal the catalytic role of a long flexible loop Nature Structural Biology. 3: 881-887. PMID 8836106 DOI: 10.1038/Nsb1096-881 |
0.653 |
|
| 1996 |
Richards JP, Bächinger HP, Goodman RH, Brennan RG. Analysis of the structural properties of cAMP-responsive element-binding protein (CREB) and phosphorylated CREB. The Journal of Biological Chemistry. 271: 13716-23. PMID 8662719 DOI: 10.1074/Jbc.271.23.13716 |
0.524 |
|
| 1996 |
Lewis M, Chang G, Horton NC, Kercher MA, Pace HC, Schumacher MA, Brennan RG, Lu P. Crystal structure of the lactose operon represser and its complexes with DNA and inducer Science. 271: 1247-1254. PMID 8638105 DOI: 10.1126/Science.271.5253.1247 |
0.694 |
|
| 1996 |
Glasfeld A, Schumacher MA, Choi KY, Zalkin H, Brennan RG. A positively charged residue bound in the minor groove does not alter the bending of a DNA duplex Journal of the American Chemical Society. 118: 13073-13074. DOI: 10.1021/Ja962416B |
0.62 |
|
| 1995 |
Nagadoi A, Nakazawa K, Morikawa S, Nakamura H, Sampei G, Mizobuchi K, Yamamoto H, Schumacher MA, Brennan RG, Nishimura Y. Conformational changes of purine repressor DNA-binding domain upon complexation with DNA Nucleic Acids Symposium Series. 63-64. PMID 8841553 |
0.42 |
|
| 1995 |
Nagadoi A, Morikawa S, Nakamura H, Enari M, Kobayashi K, Yamamoto H, Sampei G, Mizobuchi K, Schumacher MA, Brennan RG, Nishimura Y. Structural comparison of the free and DNA-bound forms of the purine repressor DNA-binding domain Structure. 3: 1217-1224. PMID 8591032 DOI: 10.1016/S0969-2126(01)00257-X |
0.716 |
|
| 1995 |
Schumacher MA, Dixon MM, Kluger R, Jones RT, Brennan RG. Allosteric transition intermediates modelled by crosslinked haemoglobins. Nature. 375: 84-7. PMID 7723849 DOI: 10.1038/375084A0 |
0.548 |
|
| 1995 |
Schumacher MA, Choi KY, Lu F, Zalkin H, Brennan RG. Mechanism of corepressor-mediated specific DNA binding by the purine repressor Cell. 83: 147-155. PMID 7553867 DOI: 10.1016/0092-8674(95)90243-0 |
0.74 |
|
| 1994 |
Schumacher MA, Choi KY, Zalkin H, Brennan RG. Crystallization and preliminary X-ray analysis of an Escherichia coli purine repressor-hypoxanthine-DNA complex Journal of Molecular Biology. 242: 302-305. PMID 8089849 DOI: 10.1006/Jmbi.1994.1580 |
0.686 |
|
| 1994 |
Schumacher MA, Choi KY, Zalkin H, Brennan RG. Crystal structure of lacl member, PurR, bound to DNA: Minor groove binding by α helices Science. 266: 763-770. PMID 7973627 DOI: 10.1126/Science.7973627 |
0.739 |
|
| 1994 |
Kwok RP, Lundblad JR, Chrivia JC, Richards JP, Bächinger HP, Brennan RG, Roberts SG, Green MR, Goodman RH. Nuclear protein CBP is a coactivator for the transcription factor CREB. Nature. 370: 223-6. PMID 7913207 DOI: 10.1038/370223A0 |
0.431 |
|
| 1993 |
Schumacher MA, Macdonald JR, Björkman J, Mowbray SL, Brennan RG. Structural analysis of the purine repressor, an Escherichia coli DNA-binding protein. The Journal of Biological Chemistry. 268: 12282-8. PMID 8509365 |
0.479 |
|
| 1993 |
Spiro C, Richards JP, Chandrasekaran S, Brennan RG, Mcmurray CT. Secondary structure creates mismatched base pairs required for high-affinity binding of cAMP response element-binding protein to the human enkephalin enhancer Proceedings of the National Academy of Sciences of the United States of America. 90: 4606-4610. PMID 8506306 DOI: 10.1073/Pnas.90.10.4606 |
0.547 |
|
| 1993 |
Brennan RG. The winged-helix DNA-binding motif: Another helix-turn-helix takeoff Cell. 74: 773-776. PMID 8374950 DOI: 10.1016/0092-8674(93)90456-Z |
0.52 |
|
| 1993 |
Loriaux MM, Rehfuss RP, Brennan RG, Goodman RH. Engineered leucine zippers show that hemiphosphorylated CREB complexes are transcriptionally active. Proceedings of the National Academy of Sciences of the United States of America. 90: 9046-50. PMID 8105470 DOI: 10.1073/Pnas.90.19.9046 |
0.39 |
|
| 1992 |
Schumacher MA, Choi KY, Zalkin H, Brennan RG. Crystallization and preliminary X-ray studies on the co-repressor binding domain of the Escherichia coli purine repressor Journal of Molecular Biology. 225: 1131-1133. PMID 1613795 DOI: 10.1016/0022-2836(92)90111-V |
0.727 |
|
| 1992 |
Wilson KP, Shewchuk LM, Brennan RG, Otsuka AJ, Matthews BW. Escherichia coli biotin holoenzyme synthetase/bio repressor crystal structure delineates the biotin- and DNA-binding domains. Proceedings of the National Academy of Sciences of the United States of America. 89: 9257-61. PMID 1409631 DOI: 10.1073/Pnas.89.19.9257 |
0.698 |
|
| 1992 |
Brennan RG. DNA recognition by the helix-turn-helix motif. Current Opinion in Structural Biology 1992, 2: 100...-108 Current Opinion in Structural Biology. 2: 100-108. DOI: 10.1016/0959-440X(92)90184-9 |
0.499 |
|
| 1991 |
Dixon MM, Brennan RG, Matthews BW. Structure of γ-chymotrypsin in the range pH 2.0 to pH 10.5 suggests that γ-chymotrypsin is a covalent acyl-enzyme adduct at low pH International Journal of Biological Macromolecules. 13: 89-96. PMID 1888717 DOI: 10.1016/0141-8130(91)90054-X |
0.475 |
|
| 1991 |
Carr DW, Stofko-Hahn RE, Fraser IDC, Bishop SM, Acott TS, Brennan RG, Scott JD. Interaction of the regulatory subunit (RII) of cAMP-dependent protein kinase with RII-anchoring proteins occurs through an amphipathic helix binding motif Journal of Biological Chemistry. 266: 14188-14192. PMID 1860836 |
0.334 |
|
| 1991 |
Brennan RG. Interactions of the helix-turn-helix binding domain. Current opinion in structural biology 1991, 1:80-88 Current Opinion in Structural Biology. 1: 80-88. DOI: 10.1016/0959-440X(91)90015-L |
0.553 |
|
| 1990 |
Brennan RG, Roderick SL, Takeda Y, Matthews BW. Protein-DNA conformational changes in the crystal structure of a λ Cro-operator complex Proceedings of the National Academy of Sciences of the United States of America. 87: 8165-8169. PMID 2146682 DOI: 10.1073/Pnas.87.20.8165 |
0.623 |
|
| 1989 |
Brennan RG, Matthews BW. Structural basis of DNA-protein recognition Trends in Biochemical Sciences. 14: 286-290. PMID 2672451 DOI: 10.1016/0968-0004(89)90066-2 |
0.653 |
|
| 1989 |
Brennan RG, Matthews BW. The helix-turn-helix DNA binding motif Journal of Biological Chemistry. 264: 1903-1906. PMID 2644244 |
0.425 |
|
| 1988 |
Brennan RG, Wozniak J, Faber R, Matthews BW. Crystallization of mutant lysozymes from bacteriophage T4 Journal of Crystal Growth. 90: 160-167. DOI: 10.1016/0022-0248(88)90311-9 |
0.524 |
|
| 1986 |
Brennan RG, Westhof E, Sundaralingam M. Structure of a Z-DNA with two different backbone chain conformations. Stabilization of the decadeoxyoligonucleotide d(CGTACGTACG) by [Co(NH3)6]3+ binding to the guanine. Journal of Biomolecular Structure & Dynamics. 3: 649-65. PMID 3271042 DOI: 10.1080/07391102.1986.10508453 |
0.497 |
|
| 1986 |
Brennan RG, Takeda Y, Kim J, Anderson WF, Matthews BW. Crystallization of a complex of cro repressor with a 17 base-pair operator Journal of Molecular Biology. 188: 115-118. PMID 2940371 DOI: 10.1016/0022-2836(86)90488-2 |
0.582 |
|
| 1986 |
Brennan RG, Kim J, Takeda Y, Anderson WF, Matthews BW. Studies on the crystallization of the cro protein-pseudo OR3 complex Journal of Crystal Growth. 76: 715-718. DOI: 10.1016/0022-0248(86)90189-2 |
0.515 |
|
| 1985 |
Brennan RG, Sundaralingam M. Crystallization and preliminary crystallographic studies of the decadeoxyoligonucleotide d(CpGpTpApCpGpTpApCpG) Journal of Molecular Biology. 181: 561-563. PMID 3999140 DOI: 10.1016/0022-2836(85)90429-2 |
0.352 |
|
| 1984 |
Brennan RG, Kondo NS, Sundaralingam M. X-ray structure of cytidine-5′-O-dimethylphosphate. Novel stacking between the ribosyl O(2′) hydroxyl oxygen atom and the base Nucleic Acids Research. 12: 6813-6825. PMID 6548306 DOI: 10.1093/Nar/12.17.6813 |
0.342 |
|
| 1984 |
Brennan RG, Kondo NS, Sundaralingam M. Crystal structure and conformation of the phosphotriester adenosine 5′-O-(diethyl phosphate). Possible steric and conformational mechanisms for the biochemical and biological effects arising from phosphate alkylation Journal of the American Chemical Society. 106: 5671-5676. DOI: 10.1002/Chin.198502056 |
0.346 |
|
| 1983 |
Wells RD, Brennan R, Chapman KA, Goodman TC, Hart PA, Hillen W, Kellogg DR, Kilpatrick MW, Klein RD, Klysik J, Lambert PF, Larson JE, Miglietta JJ, Neuendorf SK, O'Connor TR, et al. Left-handed DNA helices, supercoiling, and the B-Z junction. Cold Spring Harbor Symposia On Quantitative Biology. 47: 77-84. PMID 6345066 DOI: 10.1101/Sqb.1983.047.01.010 |
0.307 |
|
| 1983 |
Brennan RG, Prive GG, Blonski WJP, Hruska FE, Sundaralingam M. Molecular and crystal structure of O4-methyluridine. Reaction coordinates for an incipient nucleophilic attack seen by short intermolecular sugar-base interactions Journal of the American Chemical Society. 105: 7737-7742. DOI: 10.1002/Chin.198413082 |
0.302 |
|
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