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Mahmood Mohtashami, Ph.D. - Publications

Affiliations: 
2002 University of Toronto, Toronto, ON, Canada 
Area:
Neuroscience Biology, Cell Biology
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26 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Yoganathan K, Yan A, Rocha J, Trotman-Grant A, Mohtashami M, Wells L, Zúñiga-Pflücker JC, Anderson MK. Regulation of the Signal-Dependent E Protein HEBAlt Through a YYY Motif Is Required for Progression Through T Cell Development. Frontiers in Immunology. 13: 848577. PMID 35990644 DOI: 10.3389/fimmu.2022.848577  0.349
2020 Singh J, Mohtashami M, Anderson G, Zúñiga-Pflücker JC. Thymic Engraftment by -Derived Progenitor T Cells in Young and Aged Mice. Frontiers in Immunology. 11: 1850. PMID 32973763 DOI: 10.3389/Fimmu.2020.01850  0.371
2020 Elsaesser HJ, Mohtashami M, Osokine I, Snell LM, Cunningham CR, Boukhaled GM, McGavern DB, Zúñiga-Pflücker JC, Brooks DG. Chronic virus infection drives CD8 T cell-mediated thymic destruction and impaired negative selection. Proceedings of the National Academy of Sciences of the United States of America. PMID 32094187 DOI: 10.1073/Pnas.1913776117  0.357
2018 Zarin P, In TSH, Chen ELY, Singh J, Wong GW, Mohtashami M, Wiest DL, Anderson MK, Zúñiga-Pflücker JC. Integration of T Cell Receptor, Notch and Cytokine Signals Programs in Mouse γδ T Cell Effector Differentiation. Immunology and Cell Biology. PMID 29754419 DOI: 10.1111/Imcb.12164  0.361
2017 Smith MJ, Reichenbach DK, Parker SL, Riddle MJ, Mitchell J, Osum KC, Mohtashami M, Stefanski HE, Fife BT, Bhandoola A, Hogquist KA, Holländer GA, Zúñiga-Pflücker JC, Tolar J, Blazar BR. T cell progenitor therapy-facilitated thymopoiesis depends upon thymic input and continued thymic microenvironment interaction. Jci Insight. 2. PMID 28515359 DOI: 10.1172/Jci.Insight.92056  0.376
2017 Shukla S, Langley MA, Singh J, Edgar JM, Mohtashami M, Zúñiga-Pflücker JC, Zandstra PW. Progenitor T-cell differentiation from hematopoietic stem cells using Delta-like-4 and VCAM-1. Nature Methods. PMID 28394335 DOI: 10.1038/Nmeth.4258  0.405
2016 Mohtashami M, Zarin P, Zúñiga-Pflücker JC. Induction of T Cell Development In Vitro by Delta-Like (Dll)-Expressing Stromal Cells. Methods in Molecular Biology (Clifton, N.J.). 1323: 159-67. PMID 26294407 DOI: 10.1007/978-1-4939-2809-5_14  0.394
2015 Smith MJ, Webber BR, Mohtashami M, Stefanski HE, Zún˜iga-Pflücker JC, Blazar BR. Concise Review: In Vitro T-Cell Generation from Adult, Embryonic, and Induced Pluripotent Stem Cells: Many Roads to One Destination. Stem Cells (Dayton, Ohio). PMID 26227158 DOI: 10.1002/Stem.2115  0.392
2014 Zarin P, Wong GW, Mohtashami M, Wiest DL, Zúñiga-Pflücker JC. Enforcement of γδ-lineage commitment by the pre-T-cell receptor in precursors with weak γδ-TCR signals. Proceedings of the National Academy of Sciences of the United States of America. 111: 5658-63. PMID 24706811 DOI: 10.1073/Pnas.1312872111  0.41
2014 Xu H, Mohtashami M, Stewart B, Boulianne G, Trimble WS. Drosophila SNAP-29 is an essential SNARE that binds multiple proteins involved in membrane traffic. Plos One. 9: e91471. PMID 24626111 DOI: 10.1371/Journal.Pone.0091471  0.602
2014 Benveniste P, Serra P, Dervovic D, Herer E, Knowles G, Mohtashami M, Zúñiga-Pflücker JC. Notch signals are required for in vitro but not in vivo maintenance of human hematopoietic stem cells and delay the appearance of multipotent progenitors. Blood. 123: 1167-77. PMID 24363404 DOI: 10.1182/Blood-2013-07-505099  0.305
2013 Awong G, Singh J, Mohtashami M, Malm M, La Motte-Mohs RN, Benveniste PM, Serra P, Herer E, van den Brink MR, Zúñiga-Pflücker JC. Human proT-cells generated in vitro facilitate hematopoietic stem cell-derived T-lymphopoiesis in vivo and restore thymic architecture. Blood. 122: 4210-9. PMID 24215033 DOI: 10.1182/Blood-2012-12-472803  0.373
2013 Mohtashami M, Shah DK, Kianizad K, Awong G, Zúñiga-Pflücker JC. Induction of T-cell development by Delta-like 4-expressing fibroblasts. International Immunology. 25: 601-11. PMID 23988616 DOI: 10.1093/Intimm/Dxt027  0.405
2013 Smeets MF, Mackenzie-Kludas C, Mohtashami M, Zhang HH, Zúñiga-Pflücker JC, Izon DJ. Removal of myeloid cytokines from the cellular environment enhances T-cell development in vitro. International Immunology. 25: 589-99. PMID 23988615 DOI: 10.1093/Intimm/Dxt025  0.393
2013 Dervovic DD, Liang HC, Cannons JL, Elford AR, Mohtashami M, Ohashi PS, Schwartzberg PL, Zúñiga-Pflücker JC. Cellular and molecular requirements for the selection of in vitro-generated CD8 T cells reveal a role for Notch. Journal of Immunology (Baltimore, Md. : 1950). 191: 1704-15. PMID 23851691 DOI: 10.4049/Jimmunol.1300417  0.398
2012 Shah DK, Mohtashami M, Zúñiga-Pflücker JC. Role of recycling, Mindbomb1 association, and exclusion from lipid rafts of δ-like 4 for effective Notch signaling to drive T cell development. Journal of Immunology (Baltimore, Md. : 1950). 189: 5797-808. PMID 23162128 DOI: 10.4049/Jimmunol.1202469  0.444
2012 Moore AJ, Sarmiento J, Mohtashami M, Braunstein M, Zúñiga-Pflücker JC, Anderson MK. Transcriptional priming of intrathymic precursors for dendritic cell development. Development (Cambridge, England). 139: 373-84. PMID 22186727 DOI: 10.1242/Dev.069344  0.374
2010 Mohtashami M, Shah DK, Nakase H, Kianizad K, Petrie HT, Zúñiga-Pflücker JC. Direct comparison of Dll1- and Dll4-mediated Notch activation levels shows differential lymphomyeloid lineage commitment outcomes. Journal of Immunology (Baltimore, Md. : 1950). 185: 867-76. PMID 20548034 DOI: 10.4049/Jimmunol.1000782  0.389
2006 Mohtashami M, Zúñiga-Pflücker JC. Three-dimensional architecture of the thymus is required to maintain delta-like expression necessary for inducing T cell development. Journal of Immunology (Baltimore, Md. : 1950). 176: 730-4. PMID 16393955 DOI: 10.4049/Jimmunol.176.2.730  0.381
2002 Stewart BA, Mohtashami M, Rivlin P, Deitcher DL, Trimble WS, Boulianne GL. Dominant-negative NSF2 disrupts the structure and function of Drosophila neuromuscular synapses. Journal of Neurobiology. 51: 261-71. PMID 12150502 DOI: 10.1002/Neu.10059  0.594
2001 Mohtashami M, Stewart BA, Boulianne GL, Trimble WS. Analysis of the mutant Drosophila N-ethylmaleimide sensitive fusion-1 protein in comatose reveals molecular correlates of the behavioural paralysis. Journal of Neurochemistry. 77: 1407-17. PMID 11389191 DOI: 10.1046/J.1471-4159.2001.00363.X  0.609
2001 Stewart BA, Mohtashami M, Zhou L, Trimble WS, Boulianne GL. SNARE-dependent signaling at the Drosophila wing margin. Developmental Biology. 234: 13-23. PMID 11356016 DOI: 10.1006/Dbio.2001.0228  0.588
2001 Coppolino MG, Kong C, Mohtashami M, Schreiber AD, Brumell JH, Finlay BB, Grinstein S, Trimble WS. Requirement for N-ethylmaleimide-sensitive factor activity at different stages of bacterial invasion and phagocytosis. The Journal of Biological Chemistry. 276: 4772-80. PMID 11092884 DOI: 10.1074/Jbc.M007792200  0.566
2000 Stewart BA, Mohtashami M, Trimble WS, Boulianne GL. SNARE proteins contribute to calcium cooperativity of synaptic transmission. Proceedings of the National Academy of Sciences of the United States of America. 97: 13955-60. PMID 11095753 DOI: 10.1073/Pnas.250491397  0.542
1998 Foster LJ, Yeung B, Mohtashami M, Ross K, Trimble WS, Klip A. Binary interactions of the SNARE proteins syntaxin-4, SNAP23, and VAMP-2 and their regulation by phosphorylation. Biochemistry. 37: 11089-96. PMID 9693005 DOI: 10.1021/Bi980253T  0.584
1995 Nielsen S, Marples D, Birn H, Mohtashami M, Dalby NO, Trimble W, Knepper M. Expression of VAMP2-like protein in kidney collecting duct intracellular vesicles. Colocalization with aquaporin-2 water channels Journal of Clinical Investigation. 96: 1834-1844. PMID 7560075  0.343
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