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Hitesh K. Agarwal, Ph.D. - Publications

Affiliations: 
2008 University of Rhode Island, Providence, RI, United States 
Area:
Pharmaceutical Chemistry, Pharmacology
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22 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Agarwal HK, Chhikara BS, Ye G, Bhavaraju S, Dixit A, Kumar A, Doncel GF, Parang K. Synthesis and Biological Evaluation of 5'--Fatty Acyl Ester Derivatives of 3'-Fluoro-2',3'-dideoxythymidine as Potential Anti-HIV Microbicides. Molecules (Basel, Switzerland). 27. PMID 35630829 DOI: 10.3390/molecules27103352  0.731
2017 Agarwal HK, Chhikara BS, Doncel GF, Parang K. Synthesis and anti-HIV activities of unsymmetrical long chain dicarboxylate esters of dinucleoside reverse transcriptase inhibitors. Bioorganic & Medicinal Chemistry Letters. PMID 28351588 DOI: 10.1016/J.Bmcl.2017.03.031  0.687
2015 Agarwal HK, Khalil A, Ishita K, Yang W, Nakkula RJ, Wu LC, Ali T, Tiwari R, Byun Y, Barth RF, Tjarks W. Synthesis and evaluation of thymidine kinase 1-targeting carboranyl pyrimidine nucleoside analogs for boron neutron capture therapy of cancer. European Journal of Medicinal Chemistry. 100: 197-209. PMID 26087030 DOI: 10.1016/J.Ejmech.2015.05.042  0.349
2015 Pemmaraju BP, Malekar S, Agarwal HK, Tiwari RK, Oh D, Doncel GF, Worthen DR, Parang K. Design, synthesis, antiviral activity, and pre-formulation development of poly-L-arginine-fatty acyl derivatives of nucleoside reverse transcriptase inhibitors. Nucleosides, Nucleotides & Nucleic Acids. 34: 1-15. PMID 25513860 DOI: 10.1080/15257770.2014.945649  0.721
2014 Fowler BJ, Gelfand BD, Kim Y, Kerur N, Tarallo V, Hirano Y, Amarnath S, Fowler DH, Radwan M, Young MT, Pittman K, Kubes P, Agarwal HK, Parang K, Hinton DR, et al. Nucleoside reverse transcriptase inhibitors possess intrinsic anti-inflammatory activity. Science (New York, N.Y.). 346: 1000-3. PMID 25414314 DOI: 10.1126/Science.1261754  0.582
2014 Pemmaraju B, Agarwal HK, Oh D, Buckheit KW, Buckheit RW, Tiwari R, Parang K. Synthesis and Biological Evaluation of 5'-O-Dicarboxylic Fatty Acyl Monoester Derivatives of Anti-HIV Nucleoside Reverse Transcriptase Inhibitors. Tetrahedron Letters. 55: 1983-1986. PMID 24791029 DOI: 10.1016/J.Tetlet.2014.02.001  0.743
2013 Agarwal HK, Chhikara BS, Bhavaraju S, Mandal D, Doncel GF, Parang K. Emtricitabine prodrugs with improved anti-HIV activity and cellular uptake. Molecular Pharmaceutics. 10: 467-76. PMID 22917277 DOI: 10.1021/Mp300361A  0.678
2012 Hasabelnaby S, Goudah A, Agarwal HK, abd Alla MS, Tjarks W. Synthesis, chemical and enzymatic hydrolysis, and aqueous solubility of amino acid ester prodrugs of 3-carboranyl thymidine analogs for boron neutron capture therapy of brain tumors. European Journal of Medicinal Chemistry. 55: 325-34. PMID 22889558 DOI: 10.1016/J.Ejmech.2012.07.033  0.367
2012 Agarwal HK, Buckheit KW, Buckheit RW, Parang K. Synthesis and anti-HIV activities of symmetrical dicarboxylate esters of dinucleoside reverse transcriptase inhibitors. Bioorganic & Medicinal Chemistry Letters. 22: 5451-4. PMID 22858097 DOI: 10.1016/J.Bmcl.2012.07.037  0.689
2012 Shaik IH, Agarwal HK, Parang K, Mehvar R. Hepatic immunosuppressive effects of systemically administered novel dextran-methylprednisolone prodrugs with peptide linkers in rats. Journal of Pharmaceutical Sciences. 101: 4003-12. PMID 22829462 DOI: 10.1002/Jps.23274  0.533
2012 Agarwal HK, Chhikara BS, Hanley MJ, Ye G, Doncel GF, Parang K. Synthesis and biological evaluation of fatty acyl ester derivatives of (-)-2',3'-dideoxy-3'-thiacytidine. Journal of Medicinal Chemistry. 55: 4861-71. PMID 22533850 DOI: 10.1021/Jm300492Q  0.727
2012 Agarwal HK, Doncel GF, Parang K. Synthesis and anti-HIV activities of suramin conjugates of 3'-fluoro- 2',3'-dideoxythymidine and 3'-azido-2',3'-dideoxythymidine. Medicinal Chemistry (ShāRiqah (United Arab Emirates)). 8: 193-7. PMID 22385137 DOI: 10.2174/157340612800493737  0.652
2012 Agarwal HK, Chhikara BS, Quiterio M, Doncel GF, Parang K. Synthesis and anti-HIV activities of glutamate and peptide conjugates of nucleoside reverse transcriptase inhibitors. Journal of Medicinal Chemistry. 55: 2672-87. PMID 22352809 DOI: 10.1021/Jm201551M  0.671
2011 Agarwal HK, Buszek B, Ricks KG, Tjarks W. Synthesis of Closo-1,7-Carboranyl Alkyl Amines. Tetrahedron Letters. 52: 5664-5667. PMID 22003261 DOI: 10.1016/J.Tetlet.2011.08.101  0.38
2011 Agarwal HK, Loethan K, Mandal D, Doncel GF, Parang K. Synthesis and biological evaluation of fatty acyl ester derivatives of 2',3'-didehydro-2',3'-dideoxythymidine. Bioorganic & Medicinal Chemistry Letters. 21: 1917-21. PMID 21382714 DOI: 10.1016/J.Bmcl.2011.02.070  0.682
2010 Agarwal HK, Kumar A, Doncel GF, Parang K. Synthesis, antiviral and contraceptive activities of nucleoside-sodium cellulose sulfate acetate and succinate conjugates. Bioorganic & Medicinal Chemistry Letters. 20: 6993-7. PMID 20965725 DOI: 10.1016/J.Bmcl.2010.09.133  0.658
2010 Ahmadibeni Y, Dash C, Hanley MJ, Le Grice SF, Agarwal HK, Parang K. Synthesis of nucleoside 5'-O-alpha,beta-methylene-beta-triphosphates and evaluation of their potency towards inhibition of HIV-1 reverse transcriptase. Organic & Biomolecular Chemistry. 8: 1271-4. PMID 20204192 DOI: 10.1039/B922846B  0.539
2010 Penugonda S, Agarwal HK, Parang K, Mehvar R. Plasma pharmacokinetics and tissue disposition of novel dextran-methylprednisolone conjugates with peptide linkers in rats. Journal of Pharmaceutical Sciences. 99: 1626-37. PMID 19780131 DOI: 10.1002/Jps.21934  0.533
2008 Penugonda S, Kumar A, Agarwal HK, Parang K, Mehvar R. Synthesis and in vitro characterization of novel dextran-methylprednisolone conjugates with peptide linkers: effects of linker length on hydrolytic and enzymatic release of methylprednisolone and its peptidyl intermediates. Journal of Pharmaceutical Sciences. 97: 2649-64. PMID 17853426 DOI: 10.1002/Jps.21161  0.536
2008 Agarwal HK, Doncel GF, Parang K. Synthesis and anti-HIV activities of phosphate triester derivatives of 3′-fluoro-2′,3′-dideoxythymidine and 3′-azido-2′,3′-dideoxythymidine Tetrahedron Letters. 49: 4905-4907. DOI: 10.1016/J.Tetlet.2008.05.149  0.571
2007 Chimalakonda KC, Agarwal HK, Kumar A, Parang K, Mehvar R. Synthesis, analysis, in vitro characterization, and in vivo disposition of a lamivudine-dextran conjugate for selective antiviral delivery to the liver. Bioconjugate Chemistry. 18: 2097-108. PMID 17922546 DOI: 10.1021/Bc700193D  0.557
2007 Agarwal HK, Parang K. Application of solid-phase chemistry for the synthesis of 3'-fluoro-3'-deoxythymidine. Nucleosides, Nucleotides & Nucleic Acids. 26: 317-22. PMID 17454740 DOI: 10.1080/15257770701257608  0.543
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