Lloyd Cantley - Publications

Affiliations: 
Yale School of Medicine Yale University, New Haven, CT 
Area:
Medicine and Surgery, Epidemiology, Immunology

50 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Xu L, Guo J, Moledina DG, Cantley LG. Immune-mediated tubule atrophy promotes acute kidney injury to chronic kidney disease transition. Nature Communications. 13: 4892. PMID 35986026 DOI: 10.1038/s41467-022-32634-0  0.339
2022 Shin NS, Marlier A, Xu L, Doilicho N, Linberg D, Guo J, Cantley LG. Arginase-1 Is Required for Macrophage-Mediated Renal Tubule Regeneration. Journal of the American Society of Nephrology : Jasn. PMID 35577558 DOI: 10.1681/ASN.2021121548  0.324
2017 Montgomery TA, Xu L, Mason S, Chinnadurai A, Lee CG, Elias JA, Cantley LG. Breast Regression Protein-39/Chitinase 3-Like 1 Promotes Renal Fibrosis after Kidney Injury via Activation of Myofibroblasts. Journal of the American Society of Nephrology : Jasn. PMID 28679671 DOI: 10.1681/Asn.2017010110  0.397
2016 Nadkarni GN, Rao V, Ismail-Beigi F, Fonseca VA, Shah SV, Simonson MS, Cantley L, Devarajan P, Parikh CR, Coca SG. Association of Urinary Biomarkers of Inflammation, Injury, and Fibrosis with Renal Function Decline: The ACCORD Trial. Clinical Journal of the American Society of Nephrology : Cjasn. PMID 27189318 DOI: 10.2215/Cjn.12051115  0.371
2015 Golden D, Cantley LG. Casein kinase 2 prevents mesenchymal transformation by maintaining Foxc2 in the cytoplasm Oncogene. 34: 4702-4712. PMID 25486430 DOI: 10.1038/Onc.2014.395  0.311
2015 Huen SC, Huynh L, Marlier A, Lee Y, Moeckel GW, Cantley LG. GM-CSF Promotes Macrophage Alternative Activation after Renal Ischemia/Reperfusion Injury. Journal of the American Society of Nephrology : Jasn. 26: 1334-45. PMID 25388222 DOI: 10.1681/ASN.2014060612  0.365
2014 Koraishy FM, Silva C, Mason S, Wu D, Cantley LG. Hepatocyte growth factor (Hgf) stimulates low density lipoprotein receptor-related protein (Lrp) 5/6 phosphorylation and promotes canonical Wnt signaling. The Journal of Biological Chemistry. 289: 14341-50. PMID 24692544 DOI: 10.1074/Jbc.M114.563213  0.615
2014 Mason S, Hader C, Marlier A, Moeckel G, Cantley LG. Met activation is required for early cytoprotection after ischemic kidney injury. Journal of the American Society of Nephrology : Jasn. 25: 329-37. PMID 24136921 DOI: 10.1681/ASN.2013050473  0.413
2013 He CH, Lee CG, Dela Cruz CS, Lee CM, Zhou Y, Ahangari F, Ma B, Herzog EL, Rosenberg SA, Li Y, Nour AM, Parikh CR, Schmidt I, Modis Y, Cantley L, et al. Chitinase 3-like 1 regulates cellular and tissue responses via IL-13 receptor α2. Cell Reports. 4: 830-41. PMID 23972995 DOI: 10.1016/J.Celrep.2013.07.032  0.322
2013 Huen SC, Moeckel GW, Cantley LG. Macrophage-specific deletion of transforming growth factor-β1 does not prevent renal fibrosis after severe ischemia-reperfusion or obstructive injury. American Journal of Physiology. Renal Physiology. 305: F477-84. PMID 23761668 DOI: 10.1152/ajprenal.00624.2012  0.343
2013 Guo JK, Shi H, Koraishy F, Marlier A, Ding Z, Shan A, Cantley LG. The Terminator mouse is a diphtheria toxin-receptor knock-in mouse strain for rapid and efficient enrichment of desired cell lineages. Kidney International. 84: 1041-6. PMID 23739236 DOI: 10.1038/Ki.2013.202  0.597
2013 Emerling BM, Benes CH, Poulogiannis G, Bell EL, Courtney K, Liu H, Choo-Wing R, Bellinger G, Tsukazawa KS, Brown V, Signoretti S, Soltoff SP, Cantley LC. Identification of CDCP1 as a hypoxia-inducible factor 2α (HIF-2α) target gene that is associated with survival in clear cell renal cell carcinoma patients. Proceedings of the National Academy of Sciences of the United States of America. 110: 3483-8. PMID 23378636 DOI: 10.1073/Pnas.1222435110  0.322
2012 Guo JK, Marlier A, Shi H, Shan A, Ardito TA, Du ZP, Kashgarian M, Krause DS, Biemesderfer D, Cantley LG. Increased tubular proliferation as an adaptive response to glomerular albuminuria. Journal of the American Society of Nephrology : Jasn. 23: 429-37. PMID 22193389 DOI: 10.1681/Asn.2011040396  0.323
2011 Karihaloo A, Koraishy F, Huen SC, Lee Y, Merrick D, Caplan MJ, Somlo S, Cantley LG. Macrophages promote cyst growth in polycystic kidney disease. Journal of the American Society of Nephrology : Jasn. 22: 1809-14. PMID 21921140 DOI: 10.1681/Asn.2011010084  0.613
2011 Lee S, Huen S, Nishio H, Nishio S, Lee HK, Choi BS, Ruhrberg C, Cantley LG. Distinct macrophage phenotypes contribute to kidney injury and repair. Journal of the American Society of Nephrology : Jasn. 22: 317-26. PMID 21289217 DOI: 10.1681/ASN.2009060615  0.339
2010 Guo JK, Cantley LG. Cellular maintenance and repair of the kidney. Annual Review of Physiology. 72: 357-76. PMID 20148680 DOI: 10.1146/annurev.physiol.010908.163245  0.329
2010 Hader C, Marlier A, Cantley L. Mesenchymal-epithelial transition in epithelial response to injury: the role of Foxc2. Oncogene. 29: 1031-1040. PMID 19935708 DOI: 10.1038/Onc.2009.397  0.475
2009 Ma H, Saenko M, Opuko A, Togawa A, Soda K, Marlier A, Moeckel GW, Cantley LG, Ishibe S. Deletion of the Met receptor in the collecting duct decreases renal repair following ureteral obstruction. Kidney International. 76: 868-76. PMID 19675527 DOI: 10.1038/ki.2009.304  0.398
2009 Ishibe S, Karihaloo A, Ma H, Zhang J, Marlier A, Mitobe M, Togawa A, Schmitt R, Czyczk J, Kashgarian M, Geller DS, Thorgeirsson SS, Cantley LG. Met and the epidermal growth factor receptor act cooperatively to regulate final nephron number and maintain collecting duct morphology. Development (Cambridge, England). 136: 337-45. PMID 19103805 DOI: 10.1242/dev.024463  0.319
2008 Wei F, Karihaloo A, Yu Z, Marlier A, Seth P, Shibazaki S, Wang T, Sukhatme VP, Somlo S, Cantley LG. Neutrophil gelatinase-associated lipocalin suppresses cyst growth by Pkd1 null cells in vitro and in vivo. Kidney International. 74: 1310-8. PMID 18974761 DOI: 10.1038/Ki.2008.395  0.362
2008 Schmitt R, Marlier A, Cantley LG. Zag expression during aging suppresses proliferation after kidney injury. Journal of the American Society of Nephrology : Jasn. 19: 2375-83. PMID 18815245 DOI: 10.1681/ASN.2008010035  0.333
2008 Ishibe S, Cantley LG. Epithelial-mesenchymal-epithelial cycling in kidney repair. Current Opinion in Nephrology and Hypertension. 17: 379-85. PMID 18660674 DOI: 10.1097/MNH.0b013e3283046507  0.314
2008 Bi B, Guo J, Marlier A, Lin SR, Cantley LG. Erythropoietin expands a stromal cell population that can mediate renoprotection. American Journal of Physiology. Renal Physiology. 295: F1017-22. PMID 18653480 DOI: 10.1152/ajprenal.90218.2008  0.367
2008 Shibazaki S, Yu Z, Nishio S, Tian X, Thomson RB, Mitobe M, Louvi A, Velazquez H, Ishibe S, Cantley LG, Igarashi P, Somlo S. Cyst formation and activation of the extracellular regulated kinase pathway after kidney specific inactivation of Pkd1. Human Molecular Genetics. 17: 1505-16. PMID 18263604 DOI: 10.1093/Hmg/Ddn039  0.374
2007 Parikh CR, Edelstein CL, Devarajan P, Cantley L. Biomarkers of acute kidney injury: early diagnosis, pathogenesis, and recovery. Journal of Investigative Medicine : the Official Publication of the American Federation For Clinical Research. 55: 333-40. PMID 18062893 DOI: 10.2310/6650.2007.00015  0.35
2007 Bi B, Schmitt R, Israilova M, Nishio H, Cantley LG. Stromal cells protect against acute tubular injury via an endocrine effect. Journal of the American Society of Nephrology : Jasn. 18: 2486-96. PMID 17656474 DOI: 10.1681/ASN.2007020140  0.392
2006 Ishibe S, Haydu JE, Togawa A, Marlier A, Cantley LG. Cell confluence regulates hepatocyte growth factor-stimulated cell morphogenesis in a beta-catenin-dependent manner. Molecular and Cellular Biology. 26: 9232-43. PMID 17030602 DOI: 10.1128/MCB.01312-06  0.31
2006 Joly D, Ishibe S, Nickel C, Yu Z, Somlo S, Cantley LG. The polycystin 1-C-terminal fragment stimulates ERK-dependent spreading of renal epithelial cells. The Journal of Biological Chemistry. 281: 26329-39. PMID 16790429 DOI: 10.1074/jbc.M601373200  0.385
2006 Grimm DH, Karihaloo A, Cai Y, Somlo S, Cantley LG, Caplan MJ. Polycystin-2 regulates proliferation and branching morphogenesis in kidney epithelial cells. The Journal of Biological Chemistry. 281: 137-44. PMID 16278216 DOI: 10.1074/Jbc.M507845200  0.396
2005 Krause D, Cantley LG. Bone marrow plasticity revisited: protection or differentiation in the kidney tubule? The Journal of Clinical Investigation. 115: 1705-8. PMID 16007248 DOI: 10.1172/Jci25540  0.306
2005 Karihaloo A, Nickel C, Cantley LG. Signals which build a tubule. Nephron. Experimental Nephrology. 100: e40-5. PMID 15731568 DOI: 10.1159/000084111  0.35
2005 Gwira JA, Wei F, Ishibe S, Ueland JM, Barasch J, Cantley LG. Expression of neutrophil gelatinase-associated lipocalin regulates epithelial morphogenesis in vitro. The Journal of Biological Chemistry. 280: 7875-82. PMID 15637066 DOI: 10.1074/Jbc.M413192200  0.407
2004 Ishibe S, Joly D, Liu ZX, Cantley LG. Paxillin serves as an ERK-regulated scaffold for coordinating FAK and Rac activation in epithelial morphogenesis. Molecular Cell. 16: 257-67. PMID 15494312 DOI: 10.1016/j.molcel.2004.10.006  0.312
2004 Karihaloo A, Kale S, Rosenblum ND, Cantley LG. Hepatocyte growth factor-mediated renal epithelial branching morphogenesis is regulated by glypican-4 expression. Molecular and Cellular Biology. 24: 8745-52. PMID 15367691 DOI: 10.1128/Mcb.24.19.8745-8752.2004  0.38
2004 Ueland JM, Gwira J, Liu ZX, Cantley LG. The chemokine KC regulates HGF-stimulated epithelial cell morphogenesis. American Journal of Physiology. Renal Physiology. 286: F581-9. PMID 14600031 DOI: 10.1152/ajprenal.00289.2003  0.428
2003 Ishibe S, Joly D, Zhu X, Cantley LG. Phosphorylation-dependent paxillin-ERK association mediates hepatocyte growth factor-stimulated epithelial morphogenesis. Molecular Cell. 12: 1275-85. PMID 14636584  0.322
2003 Kale S, Karihaloo A, Clark PR, Kashgarian M, Krause DS, Cantley LG. Bone marrow stem cells contribute to repair of the ischemically injured renal tubule. The Journal of Clinical Investigation. 112: 42-9. PMID 12824456 DOI: 10.1172/Jci17856  0.308
2002 Nickel C, Benzing T, Sellin L, Gerke P, Karihaloo A, Liu ZX, Cantley LG, Walz G. The polycystin-1 C-terminal fragment triggers branching morphogenesis and migration of tubular kidney epithelial cells. The Journal of Clinical Investigation. 109: 481-9. PMID 11854320 DOI: 10.1172/JCI12867  0.378
2001 Karihaloo A, Karumanchi SA, Barasch J, Jha V, Nickel CH, Yang J, Grisaru S, Bush KT, Nigam S, Rosenblum ND, Sukhatme VP, Cantley LG. Endostatin regulates branching morphogenesis of renal epithelial cells and ureteric bud. Proceedings of the National Academy of Sciences of the United States of America. 98: 12509-14. PMID 11606725 DOI: 10.1073/Pnas.221205198  0.394
2001 Liu ZX, Nickel CH, Cantley LG. HGF promotes adhesion of ATP-depleted renal tubular epithelial cells in a MAPK-dependent manner. American Journal of Physiology. Renal Physiology. 281: F62-70. PMID 11399647 DOI: 10.1152/AJPRENAL.2001.281.1.F62  0.374
2000 Karihaloo A, O'Rourke DA, Nickel C, Spokes K, Cantley LG. Differential MAPK pathways utilized for HGF- and EGF-dependent renal epithelial morphogenesis. The Journal of Biological Chemistry. 276: 9166-73. PMID 11118451 DOI: 10.1074/jbc.M009963200  0.355
2000 O'Rourke DA, Liu ZX, Sellin L, Spokes K, Zeller R, Cantley LG. Hepatocyte growth factor induces MAPK-dependent formin IV translocation in renal epithelial cells. Journal of the American Society of Nephrology : Jasn. 11: 2212-2221. PMID 11095644 DOI: 10.1681/ASN.V11122212  0.445
1999 O'Rourke DA, Sakurai H, Spokes K, Kjelsberg C, Takahashi M, Nigam S, Cantley L. Expression of c-ret promotes morphogenesis and cell survival in mIMCD-3 cells. The American Journal of Physiology. 276: F581-8. PMID 10198418 DOI: 10.1152/Ajprenal.1999.276.4.F581  0.413
1997 Sakurai H, Tsukamoto T, Kjelsberg CA, Cantley LG, Nigam SK. EGF receptor ligands are a large fraction of in vitro branching morphogens secreted by embryonic kidney American Journal of Physiology - Renal Physiology. 273: F463-F472. PMID 9321921 DOI: 10.1152/Ajprenal.1997.273.3.F463  0.339
1997 Kjelsberg C, Sakurai H, Spokes K, Birchmeier C, Drummond I, Nigam S, Cantley LG. Met -/- kidneys express epithelial cells that chemotax and form tubules in response to EGF receptor ligands American Journal of Physiology-Renal Physiology. 272. PMID 9124399 DOI: 10.1152/Ajprenal.1997.272.2.F222  0.328
1997 Cantley LG. Growth factors and the kidney: regulation of epithelial cell movement and morphogenesis. The American Journal of Physiology. 271: F1103-13. PMID 8997383 DOI: 10.1152/AJPRENAL.1996.271.6.F1103  0.329
1995 Derman MP, Cunha MJ, Barros EJG, Nigam SK, Cantley LG. HGF-mediated chemotaxis and tubulogenesis require activation of the phosphatidylinositol 3-kinase American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 268: F1211-F1217. PMID 7611461 DOI: 10.1152/Ajprenal.1995.268.6.F1211  0.312
1994 Joannidis M, Spokes K, Nakamura T, Faletto D, Cantley LG. Regional expression of hepatocyte growth factor/c-met in experimental renal hypertrophy and hyperplasia. The American Journal of Physiology. 267: F231-6. PMID 8067383 DOI: 10.1152/AJPRENAL.1994.267.2.F231  0.305
1994 Cantley LG, Barros EJG, Gandhi M, Rauchman M, Nigam SK. Regulation of mitogenesis, motogenesis, and tubulogenesis by hepatocyte growth factor in renal collecting duct cells Am.J.Physiol.. 267: F271-F280. DOI: 10.1152/Ajprenal.1994.267.2.F271  0.451
1993 Heyman SN, Clark BA, Cantley L, Spokes K, Rosen S, Brezis M, Epstein FH. Effects of ioversol versus iothalamate on endothelin release and radiocontrast nephropathy. Investigative Radiology. 28: 313-8. PMID 8478171 DOI: 10.1097/00004424-199304000-00011  0.349
Show low-probability matches.