| Year |
Citation |
Score |
| 2022 |
Yoshimoto T, Kittaka M, Doan AAP, Urata R, Prideaux M, Rojas RE, Harding CV, Henry Boom W, Bonewald LF, Greenfield EM, Ueki Y. Osteocytes directly regulate osteolysis via MYD88 signaling in bacterial bone infection. Nature Communications. 13: 6648. PMID 36333322 DOI: 10.1038/s41467-022-34352-z |
0.382 |
|
| 2020 |
Samsa WE, Mamidi MK, Hausman BS, Bashur LA, Greenfield EM, Zhou G. The master developmental regulator Jab1/Cops5/Csn5 is essential for proper bone growth and survival in mice. Bone. 115733. PMID 33157284 DOI: 10.1016/j.bone.2020.115733 |
0.333 |
|
| 2020 |
Fort BP, Dubyak GR, Greenfield EM. Lysosomal disruption by orthopaedic wear particles induces activation of the NLRP3 inflammasome and macrophage cell death by distinct mechanisms. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. PMID 32779803 DOI: 10.1002/Jor.24826 |
0.464 |
|
| 2018 |
Manzano GW, Fort BP, Dubyak GR, Greenfield EM. Wear Particle-induced Priming of the NLRP3 Inflammasome Depends on Adherent Pathogen-associated Molecular Patterns and Their Cognate Toll-like Receptors: An In Vitro Study. Clinical Orthopaedics and Related Research. 476: 2442-2453. PMID 30427314 DOI: 10.1097/Corr.0000000000000548 |
0.404 |
|
| 2018 |
Bachala D, El-Refai N, Greenfield E, Aminoshariae A, Mickel A. The Effect of Lunasin on Receptor Activator of Nuclear Factor Kappa-B Ligand−mediated Osteoclast Formation from RAW 264.7 Cells Journal of Endodontics. 44: 997-999. PMID 29680727 DOI: 10.1016/J.Joen.2018.02.023 |
0.361 |
|
| 2016 |
Bechtel CP, Gebhart JJ, Tatro JM, Kiss-Toth E, Wilkinson JM, Greenfield EM. Particle-Induced Osteolysis Is Mediated by TIRAP/Mal in Vitro and in Vivo: Dependence on Adherent Pathogen-Associated Molecular Patterns. The Journal of Bone and Joint Surgery. American Volume. 98: 285-94. PMID 26888676 DOI: 10.2106/Jbjs.O.00736 |
0.381 |
|
| 2015 |
Bonsignore LA, Goldberg VM, Greenfield EM. Machine oil inhibits the osseointegration of orthopaedic implants by impairing osteoblast attachment and spreading. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 33: 979-87. PMID 25676177 DOI: 10.1002/Jor.22850 |
0.331 |
|
| 2015 |
Chen Z, Yue SX, Zhou G, Greenfield EM, Murakami S. ERK1 and ERK2 regulate chondrocyte terminal differentiation during endochondral bone formation. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 30: 765-74. PMID 25401279 DOI: 10.1002/Jbmr.2409 |
0.409 |
|
| 2015 |
MacInnes SJ, Del Vescovo E, Kiss-Toth E, Ollier WE, Kay PR, Gordon A, Greenfield EM, Wilkinson MJ. Genetic variation in inflammatory and bone turnover pathways and risk of osteolytic responses to prosthetic materials. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 33: 193-8. PMID 25399506 DOI: 10.1002/Jor.22755 |
0.414 |
|
| 2014 |
Greenfield EM. Do genetic susceptibility, Toll-like receptors, and pathogen-associated molecular patterns modulate the effects of wear? Clinical Orthopaedics and Related Research. 472: 3709-17. PMID 25034980 DOI: 10.1007/S11999-014-3786-4 |
0.384 |
|
| 2014 |
Rettew AN, Getty PJ, Greenfield EM. Receptor tyrosine kinases in osteosarcoma: not just the usual suspects. Advances in Experimental Medicine and Biology. 804: 47-66. PMID 24924168 DOI: 10.1007/978-3-319-04843-7_3 |
0.312 |
|
| 2013 |
Ouyang Z, Chen Z, Ishikawa M, Yue X, Kawanami A, Leahy P, Greenfield EM, Murakami S. Prx1 and 3.2kb Col1a1 promoters target distinct bone cell populations in transgenic mice. Bone. PMID 24513582 DOI: 10.1016/J.Bone.2013.10.016 |
0.398 |
|
| 2013 |
Chen X, Hausman BS, Luo G, Zhou G, Murakami S, Rubin J, Greenfield EM. Protein kinase inhibitor γ reciprocally regulates osteoblast and adipocyte differentiation by downregulating leukemia inhibitory factor. Stem Cells (Dayton, Ohio). 31: 2789-99. PMID 23963683 DOI: 10.1002/Stem.1524 |
0.365 |
|
| 2013 |
Bonsignore LA, Anderson JR, Lee Z, Goldberg VM, Greenfield EM. Adherent lipopolysaccharide inhibits the osseointegration of orthopedic implants by impairing osteoblast differentiation. Bone. 52: 93-101. PMID 22995462 DOI: 10.1016/J.Bone.2012.09.011 |
0.399 |
|
| 2012 |
Messerschmitt PJ, Rettew AN, Schroeder NO, Brookover RE, Jakatdar AP, Getty PJ, Greenfield EM. Osteosarcoma Phenotype Is Inhibited by 3,4-Methylenedioxy-β-nitrostyrene. Sarcoma. 2012: 479712. PMID 22701331 DOI: 10.1155/2012/479712 |
0.31 |
|
| 2012 |
Greenfield EM. Anabolic effects of intermittent PTH on osteoblasts. Current Molecular Pharmacology. 5: 127-34. PMID 21787293 DOI: 10.2174/1874-470211205020127 |
0.449 |
|
| 2011 |
Greenfield EM, Tatro JM, Smith MV, Schnaser EA, Wu D. PI3Kγ deletion reduces variability in the in vivo osteolytic response induced by orthopaedic wear particles. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 29: 1649-53. PMID 21538508 DOI: 10.1002/jor.21440 |
0.329 |
|
| 2011 |
Islam AS, Beidelschies MA, Huml A, Greenfield EM. Titanium particles activate toll-like receptor 4 independently of lipid rafts in RAW264.7 murine macrophages. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 29: 211-7. PMID 20806319 DOI: 10.1002/Jor.21199 |
0.392 |
|
| 2010 |
Greenfield EM, Beidelschies MA, Tatro JM, Goldberg VM, Hise AG. Bacterial pathogen-associated molecular patterns stimulate biological activity of orthopaedic wear particles by activating cognate Toll-like receptors. The Journal of Biological Chemistry. 285: 32378-84. PMID 20729214 DOI: 10.1074/Jbc.M110.136895 |
0.303 |
|
| 2010 |
Gordon A, Greenfield EM, Eastell R, Kiss-Toth E, Wilkinson JM. Individual susceptibility to periprosthetic osteolysis is associated with altered patterns of innate immune gene expression in response to pro-inflammatory stimuli. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 28: 1127-35. PMID 20225323 DOI: 10.1002/Jor.21135 |
0.351 |
|
| 2010 |
Rettew AN, Getty PJ, Greenfield EM. Abstract 2194: Novel receptor tyrosine kinases in osteosarcoma identified by phosphoproteomic and functional genomic screening Cancer Research. 70: 2194-2194. DOI: 10.1158/1538-7445.Am10-2194 |
0.337 |
|
| 2009 |
Lu X, Rios HF, Jiang B, Xing L, Kadlcek R, Greenfield EM, Luo G, Feng JQ. A new osteopetrosis mutant mouse strain (ntl) with odontoma-like proliferations and lack of tooth roots. European Journal of Oral Sciences. 117: 625-35. PMID 20121924 DOI: 10.1111/J.1600-0722.2009.00690.X |
0.329 |
|
| 2008 |
Beidelschies MA, Huang H, McMullen MR, Smith MV, Islam AS, Goldberg VM, Chen X, Nagy LE, Greenfield EM. Stimulation of macrophage TNFalpha production by orthopaedic wear particles requires activation of the ERK1/2/Egr-1 and NF-kappaB pathways but is independent of p38 and JNK. Journal of Cellular Physiology. 217: 652-66. PMID 18651635 DOI: 10.1002/Jcp.21539 |
0.476 |
|
| 2008 |
Greenfield EM, Bechtold J. What other biologic and mechanical factors might contribute to osteolysis? The Journal of the American Academy of Orthopaedic Surgeons. 16: S56-62. PMID 18612015 DOI: 10.5435/00124635-200800001-00012 |
0.401 |
|
| 2007 |
Smith MV, Lee MJ, Islam AS, Rohrer JL, Goldberg VM, Beidelschies MA, Greenfield EM. Inhibition of the PI3K-Akt signaling pathway reduces tumor necrosis factor-alpha production in response to titanium particles in vitro. The Journal of Bone and Joint Surgery. American Volume. 89: 1019-27. PMID 17473139 DOI: 10.2106/Jbjs.F.00615 |
0.466 |
|
| 2007 |
Chen X, Song IH, Dennis JE, Greenfield EM. Endogenous PKI gamma limits the duration of the anti-apoptotic effects of PTH and beta-adrenergic agonists in osteoblasts. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 22: 656-64. PMID 17266398 DOI: 10.1359/Jbmr.070122 |
0.318 |
|
| 2007 |
Tatro JM, Taki N, Islam AS, Goldberg VM, Rimnac CM, Doerschuk CM, Stewart MC, Greenfield EM. The balance between endotoxin accumulation and clearance during particle-induced osteolysis in murine calvaria. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 25: 361-9. PMID 17106883 DOI: 10.1002/Jor.20289 |
0.328 |
|
| 2006 |
Fan X, Rahnert JA, Murphy TC, Nanes MS, Greenfield EM, Rubin J. Response to mechanical strain in an immortalized pre-osteoblast cell is dependent on ERK1/2. Journal of Cellular Physiology. 207: 454-60. PMID 16419041 DOI: 10.1002/Jcp.20581 |
0.38 |
|
| 2006 |
Bi Y, Nielsen KL, Kilts TM, Yoon A, A Karsdal M, Wimer HF, Greenfield EM, Heegaard AM, Young MF. Biglycan deficiency increases osteoclast differentiation and activity due to defective osteoblasts. Bone. 38: 778-86. PMID 16364709 DOI: 10.1016/j.bone.2005.11.005 |
0.608 |
|
| 2006 |
Dai JC, He P, Chen X, Greenfield EM. TNFalpha and PTH utilize distinct mechanisms to induce IL-6 and RANKL expression with markedly different kinetics. Bone. 38: 509-20. PMID 16316790 DOI: 10.1016/J.Bone.2005.10.007 |
0.341 |
|
| 2005 |
Taki N, Tatro JM, Nalepka JL, Togawa D, Goldberg VM, Rimnac CM, Greenfield EM. Polyethylene and titanium particles induce osteolysis by similar, lymphocyte-independent, mechanisms. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 23: 376-83. PMID 15734251 DOI: 10.1016/J.Orthres.2004.08.023 |
0.347 |
|
| 2005 |
Greenfield EM, Bi Y, Ragab AA, Goldberg VM, Nalepka JL, Seabold JM. Does endotoxin contribute to aseptic loosening of orthopedic implants? Journal of Biomedical Materials Research. Part B, Applied Biomaterials. 72: 179-85. PMID 15449253 DOI: 10.1002/Jbm.B.30150 |
0.63 |
|
| 2002 |
Chen X, Dai JC, Greenfield EM. Termination of immediate-early gene expression after stimulation by parathyroid hormone or isoproterenol. American Journal of Physiology. Cell Physiology. 283: C1432-40. PMID 12372804 DOI: 10.1152/Ajpcell.00221.2002 |
0.345 |
|
| 2002 |
Ragab AA, Nalepka JL, Bi Y, Greenfield EM. Cytokines synergistically induce osteoclast differentiation: support by immortalized or normal calvarial cells. American Journal of Physiology. Cell Physiology. 283: C679-87. PMID 12176725 DOI: 10.1152/Ajpcell.00421.2001 |
0.6 |
|
| 2002 |
Bi Y, Collier TO, Goldberg VM, Anderson JM, Greenfield EM. Adherent endotoxin mediates biological responses of titanium particles without stimulating their phagocytosis. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 20: 696-703. PMID 12168657 DOI: 10.1016/S0736-0266(01)00176-0 |
0.633 |
|
| 2002 |
Greenfield EM, Bi Y, Ragab AA, Goldberg VM, Van De Motter RR. The role of osteoclast differentiation in aseptic loosening. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 20: 1-8. PMID 11855378 DOI: 10.1016/S0736-0266(01)00070-5 |
0.635 |
|
| 2001 |
Bi Y, Seabold JM, Kaar SG, Ragab AA, Goldberg VM, Anderson JM, Greenfield EM. Adherent endotoxin on orthopedic wear particles stimulates cytokine production and osteoclast differentiation. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 16: 2082-91. PMID 11697805 DOI: 10.1359/Jbmr.2001.16.11.2082 |
0.661 |
|
| 2001 |
Kaar SG, Ragab AA, Kaye SJ, Kilic BA, Jinno T, Goldberg VM, Bi Y, Stewart MC, Carter JR, Greenfield EM. Rapid repair of titanium particle-induced osteolysis is dramatically reduced in aged mice. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 19: 171-8. PMID 11347687 DOI: 10.1016/S0736-0266(00)00033-4 |
0.617 |
|
| 2001 |
Bi Y, Van De Motter RR, Ragab AA, Goldberg VM, Anderson JM, Greenfield EM. Titanium particles stimulate bone resorption by inducing differentiation of murine osteoclasts. The Journal of Bone and Joint Surgery. American Volume. 83: 501-8. PMID 11315778 DOI: 10.2106/00004623-200104000-00004 |
0.673 |
|
| 1999 |
Ragab AA, Van De Motter R, Lavish SA, Goldberg VM, Ninomiya JT, Carlin CR, Greenfield EM. Measurement and removal of adherent endotoxin from titanium particles and implant surfaces Journal of Orthopaedic Research. 17: 803-809. PMID 10632445 DOI: 10.1002/JOR.1100170603 |
0.322 |
|
| 1999 |
Greenfield EM, Bi Y, Miyauchi A. Regulation of osteoclast activity Life Sciences. 65: 1087-1102. PMID 10503925 DOI: 10.1016/S0024-3205(99)00156-3 |
0.63 |
|
| 1999 |
Ninomiya JT, Bi Y, Banks MA, Lavish SA, Goldberg VM, Greenfield EM. Bone marrow cells produce soluble factors that inhibit osteoclast activity. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 17: 51-8. PMID 10073647 DOI: 10.1002/Jor.1100170109 |
0.64 |
|
| 1998 |
Ragab AA, Lavish SA, Banks MA, Goldberg VM, Greenfield EM. Osteoclast differentiation requires ascorbic acid. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 13: 970-7. PMID 9626628 DOI: 10.1359/Jbmr.1998.13.6.970 |
0.388 |
|
| 1998 |
Greenfield EM. The role of interleukin-6 in stimulation of bone resorption by parathyroid hormone Cells and Materials. 7: 301-312. |
0.321 |
|
| 1997 |
Greenfield EM, Goldberg VM. Genetic determination of bone density Lancet. 350: 1263-1264. PMID 9357401 DOI: 10.1016/S0140-6736(05)62468-3 |
0.345 |
|
| 1996 |
Pollock JH, Blaha MJ, Lavish SA, Stevenson S, Greenfield EM. In vivo demonstration that parathyroid hormone and parathyroid hormone-related protein stimulate expression by osteoblasts of interleukin-6 and leukemia inhibitory factor. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 11: 754-9. PMID 8725172 DOI: 10.1002/Jbmr.5650110606 |
0.397 |
|
| 1996 |
Greenfield EM, Horowitz MC, Lavish SA. Stimulation by parathyroid hormone of interleukin-6 and leukemia inhibitory factor expression in osteoblasts is an immediate-early gene response induced by cAMP signal transduction Journal of Biological Chemistry. 271: 10984-10989. PMID 8631918 DOI: 10.1074/Jbc.271.18.10984 |
0.452 |
|
| 1995 |
Greenfield EM, Shaw SM, Gornik SA, Banks MA. Adenyl cyclase and interleukin 6 are downstream effectors of parathyroid hormone resulting in stimulation of bone resorption. The Journal of Clinical Investigation. 96: 1238-44. PMID 7657797 DOI: 10.1172/Jci118157 |
0.434 |
|
| 1993 |
Greenfield EM, Gornik SA, Horowitz MC, Donahue HJ, Shaw SM. Regulation of cytokine expression in osteoblasts by parathyroid hormone: rapid stimulation of interleukin-6 and leukemia inhibitory factor mRNA. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 8: 1163-71. PMID 8256653 DOI: 10.1002/Jbmr.5650081003 |
0.429 |
|
| 1992 |
Greenfield EM, Alvarez JI, McLaurine EA, Oursler MJ, Blair HC, Osdoby P, Teitelbaum SL, Patrick Ross F. Avian osteoblast conditioned media stimulate bone resorption by targeting multinucleating osteoclast precursors Calcified Tissue International. 51: 317-323. PMID 1422976 DOI: 10.1007/Bf00334494 |
0.366 |
|
| 1992 |
Alvarez JI, Ross FP, Athanasou NA, Blair HC, Greenfield EM, Teitelbaum SL. Osteoclast precursors circulate in avian blood Calcified Tissue International. 51: 48-53. PMID 1393777 DOI: 10.1007/Bf00296217 |
0.351 |
|
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