Kenneth M. Cadigan, Ph.D. - Publications

MCDB University of Michigan Medical School, Ann Arbor, MI, United States 
Wnt signaling, transcription, development

59 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Archbold HC, Broussard C, Chang MV, Cadigan KM. Bipartite recognition of DNA by TCF/Pangolin is remarkably flexible and contributes to transcriptional responsiveness and tissue specificity of wingless signaling. Plos Genetics. 10: e1004591. PMID 25188465 DOI: 10.1371/journal.pgen.1004591  1
2014 Zhang CU, Blauwkamp TA, Burby PE, Cadigan KM. Wnt-mediated repression via bipartite DNA recognition by TCF in the Drosophila hematopoietic system. Plos Genetics. 10: e1004509. PMID 25144371 DOI: 10.1371/journal.pgen.1004509  1
2014 Bhambhani C, Ravindranath AJ, Mentink RA, Chang MV, Betist MC, Yang YX, Koushika SP, Korswagen HC, Cadigan KM. Distinct DNA binding sites contribute to the TCF transcriptional switch in C. elegans and Drosophila. Plos Genetics. 10: e1004133. PMID 24516405 DOI: 10.1371/journal.pgen.1004133  1
2014 Ravindranath AJ, Ravindranath A, Cadigan KM. Structure-function analysis of the C-clamp of TCF/Pangolin in Wnt/ß-catenin signaling. Plos One. 9: e86180. PMID 24465946 DOI: 10.1371/journal.pone.0086180  1
2014 Ravindranath AJ, Cadigan KM. Correction: Structure-function analysis of the C-clamp of TCF/pangolin in Wnt/β-catenin signaling (PLoS ONE (2014) 9, 1 (e86180) DOI 10.1371/ journal.pone.0086180) Plos One. 9. DOI: 10.1371/journal.pone.0091378  1
2014 Bhambhani C, Cadigan KM. Finding a Needle in a Genomic Haystack: Genome-Wide Approaches to Identify Wnt/TCF Transcriptional Targets Wnt Signaling in Development and Disease: Molecular Mechanisms and Biological Functions. 73-87. DOI: 10.1002/9781118444122.ch5  1
2014 Zhang CU, Cadigan KM. An Overview of Gene Regulation by Wnt/β-Catenin Signaling Wnt Signaling in Development and Disease: Molecular Mechanisms and Biological Functions. 51-71. DOI: 10.1002/9781118444122.ch4  1
2012 Verkaar F, Cadigan KM, van Amerongen R. Celebrating 30 years of Wnt signaling. Science Signaling. 5: mr2. PMID 23233527 DOI: 10.1126/scisignal.2003714  1
2012 Cadigan KM, Waterman ML. TCF/LEFs and Wnt signaling in the nucleus. Cold Spring Harbor Perspectives in Biology. 4. PMID 23024173 DOI: 10.1101/cshperspect.a007906  1
2012 Cadigan KM. TCFs and Wnt/β-catenin signaling: more than one way to throw the switch. Current Topics in Developmental Biology. 98: 1-34. PMID 22305157 DOI: 10.1016/B978-0-12-386499-4.00001-X  1
2012 Kennell JA, Cadigan KM, Shakhmantsir I, Waldron EJ. The microRNA miR-8 is a positive regulator of pigmentation and eclosion in Drosophila. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 241: 161-8. PMID 22174085 DOI: 10.1002/dvdy.23705  1
2012 Archbold HC, Yang YX, Chen L, Cadigan KM. How do they do Wnt they do?: regulation of transcription by the Wnt/β-catenin pathway. Acta Physiologica (Oxford, England). 204: 74-109. PMID 21624092 DOI: 10.1111/j.1748-1716.2011.02293.x  1
2011 Bhambhani C, Chang JL, Akey DL, Cadigan KM. The oligomeric state of CtBP determines its role as a transcriptional co-activator and co-repressor of Wingless targets. The Embo Journal. 30: 2031-43. PMID 21468031 DOI: 10.1038/emboj.2011.100  1
2010 Cadigan KM. Receptor endocytosis: Frizzled joins the ubiquitin club. The Embo Journal. 29: 2099-100. PMID 20606702 DOI: 10.1038/emboj.2010.132  1
2009 Cadigan KM, Peifer M. Wnt signaling from development to disease: insights from model systems. Cold Spring Harbor Perspectives in Biology. 1: a002881. PMID 20066091 DOI: 10.1101/cshperspect.a002881  1
2009 Kennell J, Cadigan KM. APC and beta-catenin degradation. Advances in Experimental Medicine and Biology. 656: 1-12. PMID 19928348 DOI: 10.1007/978-1-4419-1145-2_1  1
2009 Fang M, Ren H, Liu J, Cadigan KM, Patel SR, Dressler GR. Drosophila ptip is essential for anterior/posterior patterning in development and interacts with the PcG and trxG pathways. Development (Cambridge, England). 136: 1929-38. PMID 19429789 DOI: 10.1242/dev.040022  1
2008 Chang MV, Chang JL, Gangopadhyay A, Shearer A, Cadigan KM. Activation of wingless targets requires bipartite recognition of DNA by TCF. Current Biology : Cb. 18: 1877-81. PMID 19062282 DOI: 10.1016/j.cub.2008.10.047  1
2008 Cadigan KM. Wnt-beta-catenin signaling. Current Biology : Cb. 18: R943-7. PMID 18957245 DOI: 10.1016/j.cub.2008.08.017  1
2008 Kennell JA, Gerin I, MacDougald OA, Cadigan KM. The microRNA miR-8 is a conserved negative regulator of Wnt signaling. Proceedings of the National Academy of Sciences of the United States of America. 105: 15417-22. PMID 18824696 DOI: 10.1073/pnas.0807763105  1
2008 Grieder NC, Caussinus E, Parker DS, Cadigan K, Affolter M, Luschnig S. gammaCOP is required for apical protein secretion and epithelial morphogenesis in Drosophila melanogaster. Plos One. 3: e3241. PMID 18802472 DOI: 10.1371/journal.pone.0003241  1
2008 Liu YI, Chang MV, Li HE, Barolo S, Chang JL, Blauwkamp TA, Cadigan KM. The chromatin remodelers ISWI and ACF1 directly repress Wingless transcriptional targets. Developmental Biology. 323: 41-52. PMID 18786525 DOI: 10.1016/j.ydbio.2008.08.011  1
2008 Chang JL, Chang MV, Barolo S, Cadigan KM. Regulation of the feedback antagonist naked cuticle by Wingless signaling. Developmental Biology. 321: 446-54. PMID 18585374 DOI: 10.1016/j.ydbio.2008.05.551  1
2008 Blauwkamp TA, Chang MV, Cadigan KM. Novel TCF-binding sites specify transcriptional repression by Wnt signalling. The Embo Journal. 27: 1436-46. PMID 18418383 DOI: 10.1038/emboj.2008.80  1
2008 Cadigan KM. Wnt/beta-catenin signaling: turning the switch. Developmental Cell. 14: 322-3. PMID 18331712 DOI: 10.1016/j.devcel.2008.02.006  1
2008 Chang JL, Lin HV, Blauwkamp TA, Cadigan KM. Spenito and Split ends act redundantly to promote Wingless signaling. Developmental Biology. 314: 100-11. PMID 18174108 DOI: 10.1016/j.ydbio.2007.11.023  1
2008 Parker DS, Ni YY, Chang JL, Li J, Cadigan KM. Wingless signaling induces widespread chromatin remodeling of target loci. Molecular and Cellular Biology. 28: 1815-28. PMID 18160704 DOI: 10.1128/MCB.01230-07  1
2007 Li J, Sutter C, Parker DS, Blauwkamp T, Fang M, Cadigan KM. CBP/p300 are bimodal regulators of Wnt signaling. The Embo Journal. 26: 2284-94. PMID 17410209 DOI: 10.1038/sj.emboj.7601667  1
2007 Feng Y, Bommer GT, Zhai Y, Akyol A, Hinoi T, Winer I, Lin HV, Cadigan KM, Cho KR, Fearon ER. Drosophila split ends homologue SHARP functions as a positive regulator of Wnt/beta-catenin/T-cell factor signaling in neoplastic transformation. Cancer Research. 67: 482-91. PMID 17234755 DOI: 10.1158/0008-5472.CAN-06-2314  1
2007 Guan J, Li H, Rogulja A, Axelrod JD, Cadigan KM. The Drosophila casein kinase Iepsilon/delta Discs overgrown promotes cell survival via activation of DIAP1 expression. Developmental Biology. 303: 16-28. PMID 17134692 DOI: 10.1016/j.ydbio.2006.10.028  1
2007 Parker DS, Blauwkamp T, Cadigan KM. Wnt/β-catenin-mediated transcriptional regulation Advances in Developmental Biology. 17: 1-60. DOI: 10.1016/S1574-3349(06)17001-5  1
2006 Fang M, Li J, Blauwkamp T, Bhambhani C, Campbell N, Cadigan KM. C-terminal-binding protein directly activates and represses Wnt transcriptional targets in Drosophila. The Embo Journal. 25: 2735-45. PMID 16710294 DOI: 10.1038/sj.emboj.7601153  1
2006 Cadigan KM, Liu YI. Wnt signaling: complexity at the surface. Journal of Cell Science. 119: 395-402. PMID 16443747 DOI: 10.1242/jcs.02826  1
2005 Fearon ER, Cadigan KM. Cell biology. Wnt signaling glows with RNAi. Science (New York, N.Y.). 308: 801-3. PMID 15879199 DOI: 10.1126/science.1112622  1
2005 Kon C, Cadigan KM, da Silva SL, Nusse R. Developmental roles of the Mi-2/NURD-associated protein p66 in Drosophila. Genetics. 169: 2087-100. PMID 15695365 DOI: 10.1534/genetics.104.034595  1
2004 Lin HV, Rogulja A, Cadigan KM. Wingless eliminates ommatidia from the edge of the developing eye through activation of apoptosis. Development (Cambridge, England). 131: 2409-18. PMID 15128670 DOI: 10.1242/dev.01104  1
2003 Zhou H, Cadigan KM, Thiele DJ. A copper-regulated transporter required for copper acquisition, pigmentation, and specific stages of development in Drosophila melanogaster. The Journal of Biological Chemistry. 278: 48210-8. PMID 12966081 DOI: 10.1074/jbc.M309820200  1
2003 Lin HV, Doroquez DB, Cho S, Chen F, Rebay I, Cadigan KM. Splits ends is a tissue/promoter specific regulator of Wingless signaling. Development (Cambridge, England). 130: 3125-35. PMID 12783785  1
2002 Cadigan KM. Wnt signaling--20 years and counting. Trends in Genetics : Tig. 18: 340-2. PMID 12127767 DOI: 10.1016/S0168-9525(02)02707-5  1
2002 Cadigan KM. Regulating morphogen gradients in the Drosophila wing. Seminars in Cell & Developmental Biology. 13: 83-90. PMID 12127140 DOI: 10.1016/S1084-9521(02)00014-9  1
2002 Cadigan KM, Jou AD, Nusse R. Wingless blocks bristle formation and morphogenetic furrow progression in the eye through repression of Daughterless. Development (Cambridge, England). 129: 3393-402. PMID 12091309  1
2002 Parker DS, Jemison J, Cadigan KM. Pygopus, a nuclear PHD-finger protein required for Wingless signaling in Drosophila. Development (Cambridge, England). 129: 2565-76. PMID 12015286  1
2001 Rousset R, Mack JA, Wharton KA, Axelrod JD, Cadigan KM, Fish MP, Nusse R, Scott MP. Naked cuticle targets dishevelled to antagonize Wnt signal transduction. Genes & Development. 15: 658-71. PMID 11274052 DOI: 10.1101/gad.869201  1
2000 Nusse R, Rulifson E, Fish M, Harryman-Samos C, Brink M, Wu CH, Cadigan K. Interactions between wingless and frizzled molecules in Drosophila. Ernst Schering Research Foundation Workshop. 1-11. PMID 10943301  1
1999 Bhanot P, Fish M, Jemison JA, Nusse R, Nathans J, Cadigan KM. Frizzled and Dfrizzled-2 function as redundant receptors for Wingless during Drosophila embryonic development. Development (Cambridge, England). 126: 4175-86. PMID 10457026  1
1998 Cadigan KM, Fish MP, Rulifson EJ, Nusse R. Wingless repression of Drosophila frizzled 2 expression shapes the Wingless morphogen gradient in the wing. Cell. 93: 767-77. PMID 9630221 DOI: 10.1016/S0092-8674(00)81438-5  1
1997 Nusse R, Samos CH, Brink M, Willert K, Cadigan KM, Wodarz A, Fish M, Rulifson E. Cell culture and whole animal approaches to understanding signaling by Wnt proteins in Drosophila. Cold Spring Harbor Symposia On Quantitative Biology. 62: 185-90. PMID 9598351  1
1997 Cadigan KM, Nusse R. Wnt signaling: a common theme in animal development. Genes & Development. 11: 3286-305. PMID 9407023  1
1997 Cadigan KM, Nusse R. Wnt meeting 1996. Biochimica Et Biophysica Acta. 1332: R1-5. PMID 9061012 DOI: 10.1016/S0304-419X(96)00037-6  1
1996 Cadigan KM, Nusse R. wingless signaling in the Drosophila eye and embryonic epidermis. Development (Cambridge, England). 122: 2801-12. PMID 8787754  1
1994 Chang TY, Chang CC, Cadigan KM. The structure of acyl coenzyme A-cholesterol acyltransferase and its potential relevance to atherosclerosis. Trends in Cardiovascular Medicine. 4: 223-30. PMID 21244871 DOI: 10.1016/1050-1738(94)90038-8  1
1994 Cadigan KM, Grossniklaus U, Gehring WJ. Functional redundancy: the respective roles of the two sloppy paired genes in Drosophila segmentation. Proceedings of the National Academy of Sciences of the United States of America. 91: 6324-8. PMID 8022780 DOI: 10.1073/pnas.91.14.6324  1
1994 Cadigan KM, Grossniklaus U, Gehring WJ. Localized expression of sloppy paired protein maintains the polarity of Drosophila parasegments. Genes & Development. 8: 899-913. PMID 7926775  1
1994 Grossniklaus U, Cadigan KM, Gehring WJ. Three maternal coordinate systems cooperate in the patterning of the Drosophila head. Development (Cambridge, England). 120: 3155-71. PMID 7720559  1
1993 Chang CC, Huh HY, Cadigan KM, Chang TY. Molecular cloning and functional expression of human acyl-coenzyme A:cholesterol acyltransferase cDNA in mutant Chinese hamster ovary cells. The Journal of Biological Chemistry. 268: 20747-55. PMID 8407899  1
1990 Cadigan KM, Spillane DM, Chang TY. Isolation and characterization of Chinese hamster ovary cell mutants defective in intracellular low density lipoprotein-cholesterol trafficking. The Journal of Cell Biology. 110: 295-308. PMID 2404988  1
1989 Cadigan KM, Chang CC, Chang TY. Isolation of Chinese hamster ovary cell lines expressing human acyl-coenzyme A/cholesterol acyltransferase activity. The Journal of Cell Biology. 108: 2201-10. PMID 2738092  1
1988 Cadigan KM, Heider JG, Chang TY. Isolation and characterization of Chinese hamster ovary cell mutants deficient in acyl-coenzyme A:cholesterol acyltransferase activity. The Journal of Biological Chemistry. 263: 274-82. PMID 3335499  1
1988 Cadigan KM, Chang TY. A simple method for reconstitution of CHO cell and human fibroblast acyl coenzyme A: cholesterol acyltransferase activity into liposomes. Journal of Lipid Research. 29: 1683-92. PMID 3244018  1
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