| Year |
Citation |
Score |
| 2019 |
Zhao L, Jin Y, Donahue K, Tsui M, Fish M, Logan CY, Wang B, Nusse R. Tissue repair in the mouse liver following acute carbon tetrachloride depends on injury-induced Wnt/β-catenin signaling. Hepatology (Baltimore, Md.). PMID 30762896 DOI: 10.1002/hep.30563 |
0.48 |
|
| 2018 |
Peng WC, Logan CY, Fish M, Anbarchian T, Aguisanda F, Álvarez-Varela A, Wu P, Jin Y, Zhu J, Li B, Grompe M, Wang B, Nusse R. Inflammatory Cytokine TNFα Promotes the Long-Term Expansion of Primary Hepatocytes in 3D Culture. Cell. 175: 1607-1619.e15. PMID 30500539 DOI: 10.1016/j.cell.2018.11.012 |
0.48 |
|
| 2018 |
Wiese KE, Nusse R, van Amerongen R. Wnt signalling: conquering complexity. Development (Cambridge, England). 145. PMID 29945986 DOI: 10.1242/dev.165902 |
0.4 |
|
| 2017 |
Tan SH, Nusse R. In vivo lineage tracing reveals Axin2-expressing, long-lived cortical thymic epithelial progenitors in the postnatal thymus. Plos One. 12: e0184582. PMID 28886197 DOI: 10.1371/journal.pone.0184582 |
0.4 |
|
| 2016 |
Loh KM, van Amerongen R, Nusse R. Generating Cellular Diversity and Spatial Form: Wnt Signaling and the Evolution of Multicellular Animals. Developmental Cell. 38: 643-655. PMID 27676437 DOI: 10.1016/j.devcel.2016.08.011 |
0.4 |
|
| 2015 |
Wang B, Zhao L, Fish M, Logan CY, Nusse R. Self-renewing diploid Axin2(+) cells fuel homeostatic renewal of the liver. Nature. 524: 180-5. PMID 26245375 DOI: 10.1038/nature14863 |
1 |
|
| 2015 |
Lee SH, Johnson DT, Luong R, Yu EJ, Cunha GR, Nusse R, Sun Z. Wnt/β-Catenin-Responsive Cells in Prostatic Development and Regeneration. Stem Cells (Dayton, Ohio). PMID 26220362 DOI: 10.1002/stem.2096 |
1 |
|
| 2015 |
Guenther CA, Wang Z, Li E, Tran MC, Logan CY, Nusse R, Pantalena-Filho L, Yang GP, Kingsley DM. A distinct regulatory region of the Bmp5 locus activates gene expression following adult bone fracture or soft tissue injury. Bone. 77: 31-41. PMID 25886903 DOI: 10.1016/j.bone.2015.04.010 |
1 |
|
| 2015 |
Nusse R. Cell signalling: Disarming Wnt. Nature. 519: 163-4. PMID 25731170 DOI: 10.1038/nature14208 |
1 |
|
| 2015 |
Sigal M, Rothenberg ME, Logan CY, Lee JY, Honaker RW, Cooper RL, Passarelli B, Camorlinga M, Bouley DM, Alvarez G, Nusse R, Torres J, Amieva MR. Helicobacter pylori Activates and Expands Lgr5(+) Stem Cells Through Direct Colonization of the Gastric Glands. Gastroenterology. 148: 1392-1404.e21. PMID 25725293 DOI: 10.1053/j.gastro.2015.02.049 |
1 |
|
| 2014 |
Tan SH, Senarath-Yapa K, Chung MT, Longaker MT, Wu JY, Nusse R. Wnts produced by Osterix-expressing osteolineage cells regulate their proliferation and differentiation. Proceedings of the National Academy of Sciences of the United States of America. 111: E5262-71. PMID 25422448 DOI: 10.1073/pnas.1420463111 |
1 |
|
| 2014 |
Clevers H, Loh KM, Nusse R. Stem cell signaling. An integral program for tissue renewal and regeneration: Wnt signaling and stem cell control. Science (New York, N.Y.). 346: 1248012. PMID 25278615 DOI: 10.1126/science.1248012 |
1 |
|
| 2014 |
Rinkevich Y, Montoro DT, Contreras-Trujillo H, Harari-Steinberg O, Newman AM, Tsai JM, Lim X, Van-Amerongen R, Bowman A, Januszyk M, Pleniceanu O, Nusse R, Longaker MT, Weissman IL, Dekel B. In vivo clonal analysis reveals lineage-restricted progenitor characteristics in mammalian kidney development, maintenance, and regeneration. Cell Reports. 7: 1270-83. PMID 24835991 DOI: 10.1016/j.celrep.2014.04.018 |
1 |
|
| 2014 |
Green J, Nusse R, van Amerongen R. The role of Ryk and Ror receptor tyrosine kinases in Wnt signal transduction. Cold Spring Harbor Perspectives in Biology. 6. PMID 24370848 DOI: 10.1101/cshperspect.a009175 |
1 |
|
| 2013 |
Lim X, Tan SH, Koh WL, Chau RM, Yan KS, Kuo CJ, van Amerongen R, Klein AM, Nusse R. Interfollicular epidermal stem cells self-renew via autocrine Wnt signaling. Science (New York, N.Y.). 342: 1226-30. PMID 24311688 DOI: 10.1126/science.1239730 |
1 |
|
| 2013 |
Sugiyama T, Benitez CM, Ghodasara A, Liu L, McLean GW, Lee J, Blauwkamp TA, Nusse R, Wright CV, Gu G, Kim SK. Reconstituting pancreas development from purified progenitor cells reveals genes essential for islet differentiation. Proceedings of the National Academy of Sciences of the United States of America. 110: 12691-6. PMID 23852729 DOI: 10.1073/pnas.1304507110 |
1 |
|
| 2013 |
Chu ML, Ahn VE, Choi HJ, Daniels DL, Nusse R, Weis WI. structural Studies of Wnts and identification of an LRP6 binding site. Structure (London, England : 1993). 21: 1235-42. PMID 23791946 DOI: 10.1016/j.str.2013.05.006 |
1 |
|
| 2013 |
Bowman AN, van Amerongen R, Palmer TD, Nusse R. Lineage tracing with Axin2 reveals distinct developmental and adult populations of Wnt/β-catenin-responsive neural stem cells. Proceedings of the National Academy of Sciences of the United States of America. 110: 7324-9. PMID 23589866 DOI: 10.1073/pnas.1305411110 |
1 |
|
| 2013 |
Green JL, La J, Yum KW, Desai P, Rodewald LW, Zhang X, Leblanc M, Nusse R, Lewis MT, Wahl GM. Paracrine Wnt signaling both promotes and inhibits human breast tumor growth. Proceedings of the National Academy of Sciences of the United States of America. 110: 6991-6. PMID 23559372 DOI: 10.1073/pnas.1303671110 |
1 |
|
| 2013 |
Habib SJ, Chen BC, Tsai FC, Anastassiadis K, Meyer T, Betzig E, Nusse R. A localized Wnt signal orients asymmetric stem cell division in vitro. Science (New York, N.Y.). 339: 1445-8. PMID 23520113 DOI: 10.1126/science.1231077 |
1 |
|
| 2013 |
Jan TA, Chai R, Sayyid ZN, van Amerongen R, Xia A, Wang T, Sinkkonen ST, Zeng YA, Levin JR, Heller S, Nusse R, Cheng AG. Tympanic border cells are Wnt-responsive and can act as progenitors for postnatal mouse cochlear cells. Development (Cambridge, England). 140: 1196-206. PMID 23444352 DOI: 10.1242/dev.087528 |
1 |
|
| 2013 |
Ardehali R, Ali SR, Inlay MA, Abilez OJ, Chen MQ, Blauwkamp TA, Yazawa M, Gong Y, Nusse R, Drukker M, Weissman IL. Prospective isolation of human embryonic stem cell-derived cardiovascular progenitors that integrate into human fetal heart tissue. Proceedings of the National Academy of Sciences of the United States of America. 110: 3405-10. PMID 23391730 DOI: 10.1073/pnas.1220832110 |
1 |
|
| 2013 |
Lim X, Nusse R. Wnt signaling in skin development, homeostasis, and disease. Cold Spring Harbor Perspectives in Biology. 5. PMID 23209129 DOI: 10.1101/cshperspect.a008029 |
1 |
|
| 2012 |
Blauwkamp TA, Nigam S, Ardehali R, Weissman IL, Nusse R. Endogenous Wnt signalling in human embryonic stem cells generates an equilibrium of distinct lineage-specified progenitors. Nature Communications. 3: 1070. PMID 22990866 DOI: 10.1038/ncomms2064 |
1 |
|
| 2012 |
Willert K, Nusse R. Wnt proteins. Cold Spring Harbor Perspectives in Biology. 4: a007864. PMID 22952392 DOI: 10.1101/cshperspect.a007864 |
1 |
|
| 2012 |
van Amerongen R, Bowman AN, Nusse R. Developmental stage and time dictate the fate of Wnt/β-catenin-responsive stem cells in the mammary gland. Cell Stem Cell. 11: 387-400. PMID 22863533 DOI: 10.1016/j.stem.2012.05.023 |
1 |
|
| 2012 |
van Amerongen R, Fuerer C, Mizutani M, Nusse R. Wnt5a can both activate and repress Wnt/β-catenin signaling during mouse embryonic development. Developmental Biology. 369: 101-14. PMID 22771246 DOI: 10.1016/j.ydbio.2012.06.020 |
1 |
|
| 2012 |
Clevers H, Nusse R. Wnt/β-catenin signaling and disease. Cell. 149: 1192-205. PMID 22682243 DOI: 10.1016/j.cell.2012.05.012 |
1 |
|
| 2012 |
Nusse R, Varmus H. Three decades of Wnts: a personal perspective on how a scientific field developed. The Embo Journal. 31: 2670-84. PMID 22617420 DOI: 10.1038/emboj.2012.146 |
1 |
|
| 2012 |
Chai R, Kuo B, Wang T, Liaw EJ, Xia A, Jan TA, Liu Z, Taketo MM, Oghalai JS, Nusse R, Zuo J, Cheng AG. Wnt signaling induces proliferation of sensory precursors in the postnatal mouse cochlea. Proceedings of the National Academy of Sciences of the United States of America. 109: 8167-72. PMID 22562792 DOI: 10.1073/pnas.1202774109 |
1 |
|
| 2012 |
Nusse R. Wnt signaling. Cold Spring Harbor Perspectives in Biology. 4. PMID 22550232 DOI: 10.1101/cshperspect.a011163 |
1 |
|
| 2012 |
Edris B, Espinosa I, Mühlenberg T, Mikels A, Lee CH, Steigen SE, Zhu S, Montgomery KD, Lazar AJ, Lev D, Fletcher JA, Beck AH, West RB, Nusse R, van de Rijn M. ROR2 is a novel prognostic biomarker and a potential therapeutic target in leiomyosarcoma and gastrointestinal stromal tumour. The Journal of Pathology. 227: 223-33. PMID 22294416 DOI: 10.1002/path.3986 |
1 |
|
| 2012 |
Mulligan KA, Fuerer C, Ching W, Fish M, Willert K, Nusse R. Secreted Wingless-interacting molecule (Swim) promotes long-range signaling by maintaining Wingless solubility. Proceedings of the National Academy of Sciences of the United States of America. 109: 370-7. PMID 22203956 DOI: 10.1073/pnas.1119197109 |
1 |
|
| 2011 |
McElwain MA, Ko DC, Gordon MD, Fyrst H, Saba JD, Nusse R. A suppressor/enhancer screen in Drosophila reveals a role for wnt-mediated lipid metabolism in primordial germ cell migration. Plos One. 6: e26993. PMID 22069480 DOI: 10.1371/journal.pone.0026993 |
1 |
|
| 2011 |
Bowman A, Nusse R. Location, location, location: FoxM1 mediates β-catenin nuclear translocation and promotes glioma tumorigenesis. Cancer Cell. 20: 415-6. PMID 22014565 DOI: 10.1016/j.ccr.2011.10.003 |
1 |
|
| 2011 |
ten Berge D, Kurek D, Blauwkamp T, Koole W, Maas A, Eroglu E, Siu RK, Nusse R. Embryonic stem cells require Wnt proteins to prevent differentiation to epiblast stem cells. Nature Cell Biology. 13: 1070-5. PMID 21841791 DOI: 10.1038/ncb2314 |
1 |
|
| 2011 |
Fancy SP, Harrington EP, Yuen TJ, Silbereis JC, Zhao C, Baranzini SE, Bruce CC, Otero JJ, Huang EJ, Nusse R, Franklin RJ, Rowitch DH. Axin2 as regulatory and therapeutic target in newborn brain injury and remyelination. Nature Neuroscience. 14: 1009-16. PMID 21706018 DOI: 10.1038/nn.2855 |
1 |
|
| 2010 |
Zeng YA, Nusse R. Wnt proteins are self-renewal factors for mammary stem cells and promote their long-term expansion in culture. Cell Stem Cell. 6: 568-77. PMID 20569694 DOI: 10.1016/j.stem.2010.03.020 |
1 |
|
| 2010 |
Minear S, Leucht P, Jiang J, Liu B, Zeng A, Fuerer C, Nusse R, Helms JA. Wnt proteins promote bone regeneration. Science Translational Medicine. 2: 29ra30. PMID 20427820 DOI: 10.1126/scitranslmed.3000231 |
1 |
|
| 2010 |
Fuerer C, Nusse R. Lentiviral vectors to probe and manipulate the Wnt signaling pathway. Plos One. 5: e9370. PMID 20186325 DOI: 10.1371/journal.pone.0009370 |
1 |
|
| 2010 |
Fuerer C, Habib SJ, Nusse R. A study on the interactions between heparan sulfate proteoglycans and Wnt proteins. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 239: 184-90. PMID 19705435 DOI: 10.1002/dvdy.22067 |
1 |
|
| 2009 |
van Amerongen R, Nusse R. Towards an integrated view of Wnt signaling in development. Development (Cambridge, England). 136: 3205-14. PMID 19736321 DOI: 10.1242/dev.033910 |
1 |
|
| 2009 |
Mikels A, Minami Y, Nusse R. Ror2 receptor requires tyrosine kinase activity to mediate Wnt5A signaling. The Journal of Biological Chemistry. 284: 30167-76. PMID 19720827 DOI: 10.1074/jbc.M109.041715 |
1 |
|
| 2009 |
Park JI, Venteicher AS, Hong JY, Choi J, Jun S, Shkreli M, Chang W, Meng Z, Cheung P, Ji H, McLaughlin M, Veenstra TD, Nusse R, McCrea PD, Artandi SE. Telomerase modulates Wnt signalling by association with target gene chromatin. Nature. 460: 66-72. PMID 19571879 DOI: 10.1038/nature08137 |
1 |
|
| 2009 |
Wright TM, Brannon AR, Gordan JD, Mikels AJ, Mitchell C, Chen S, Espinosa I, van de Rijn M, Pruthi R, Wallen E, Edwards L, Nusse R, Rathmell WK. Ror2, a developmentally regulated kinase, promotes tumor growth potential in renal cell carcinoma. Oncogene. 28: 2513-23. PMID 19448672 DOI: 10.1038/onc.2009.116 |
1 |
|
| 2008 |
Marston DJ, Roh M, Mikels AJ, Nusse R, Goldstein B. Wnt signaling during Caenorhabditis elegans embryonic development. Methods in Molecular Biology (Clifton, N.J.). 469: 103-11. PMID 19109706 DOI: 10.1007/978-1-60327-469-9 |
1 |
|
| 2008 |
Nusse R, Fuerer C, Ching W, Harnish K, Logan C, Zeng A, ten Berge D, Kalani Y. Wnt signaling and stem cell control. Cold Spring Harbor Symposia On Quantitative Biology. 73: 59-66. PMID 19028988 DOI: 10.1101/sqb.2008.73.035 |
1 |
|
| 2008 |
ten Berge D, Koole W, Fuerer C, Fish M, Eroglu E, Nusse R. Wnt signaling mediates self-organization and axis formation in embryoid bodies. Cell Stem Cell. 3: 508-18. PMID 18983966 DOI: 10.1016/j.stem.2008.09.013 |
1 |
|
| 2008 |
Kalani MY, Cheshier SH, Cord BJ, Bababeygy SR, Vogel H, Weissman IL, Palmer TD, Nusse R. Wnt-mediated self-renewal of neural stem/progenitor cells. Proceedings of the National Academy of Sciences of the United States of America. 105: 16970-5. PMID 18957545 DOI: 10.1073/pnas.0808616105 |
1 |
|
| 2008 |
Leucht P, Minear S, Ten Berge D, Nusse R, Helms JA. Translating insights from development into regenerative medicine: the function of Wnts in bone biology. Seminars in Cell & Developmental Biology. 19: 434-43. PMID 18824114 DOI: 10.1016/j.semcdb.2008.09.002 |
1 |
|
| 2008 |
ten Berge D, Brugmann SA, Helms JA, Nusse R. Wnt and FGF signals interact to coordinate growth with cell fate specification during limb development. Development (Cambridge, England). 135: 3247-57. PMID 18776145 DOI: 10.1242/dev.023176 |
1 |
|
| 2008 |
van Amerongen R, Mikels A, Nusse R. Alternative wnt signaling is initiated by distinct receptors. Science Signaling. 1: re9. PMID 18765832 DOI: 10.1126/scisignal.135re9 |
1 |
|
| 2008 |
Groen RW, Oud ME, Schilder-Tol EJ, Overdijk MB, ten Berge D, Nusse R, Spaargaren M, Pals ST. Illegitimate WNT pathway activation by beta-catenin mutation or autocrine stimulation in T-cell malignancies. Cancer Research. 68: 6969-77. PMID 18757411 DOI: 10.1158/0008-5472.CAN-08-1322 |
1 |
|
| 2008 |
Morrell NT, Leucht P, Zhao L, Kim JB, ten Berge D, Ponnusamy K, Carre AL, Dudek H, Zachlederova M, McElhaney M, Brunton S, Gunzner J, Callow M, Polakis P, Costa M, ... ... Nusse R, et al. Liposomal packaging generates Wnt protein with in vivo biological activity. Plos One. 3: e2930. PMID 18698373 DOI: 10.1371/journal.pone.0002930 |
1 |
|
| 2008 |
Gordon MD, Ayres JS, Schneider DS, Nusse R. Pathogenesis of listeria-infected Drosophila wntD mutants is associated with elevated levels of the novel immunity gene edin. Plos Pathogens. 4: e1000111. PMID 18654628 DOI: 10.1371/journal.ppat.1000111 |
1 |
|
| 2008 |
Chen WS, Antic D, Matis M, Logan CY, Povelones M, Anderson GA, Nusse R, Axelrod JD. Asymmetric homotypic interactions of the atypical cadherin flamingo mediate intercellular polarity signaling. Cell. 133: 1093-105. PMID 18555784 DOI: 10.1016/j.cell.2008.04.048 |
1 |
|
| 2008 |
Ching W, Hang HC, Nusse R. Lipid-independent secretion of a Drosophila Wnt protein. The Journal of Biological Chemistry. 283: 17092-8. PMID 18430724 DOI: 10.1074/jbc.M802059200 |
1 |
|
| 2008 |
Nusse R. Wnt signaling and stem cell control. Cell Research. 18: 523-7. PMID 18392048 DOI: 10.1038/cr.2008.47 |
1 |
|
| 2008 |
Rinn JL, Wang JK, Allen N, Brugmann SA, Mikels AJ, Liu H, Ridky TW, Stadler HS, Nusse R, Helms JA, Chang HY. A dermal HOX transcriptional program regulates site-specific epidermal fate. Genes & Development. 22: 303-7. PMID 18245445 DOI: 10.1101/gad.1610508 |
1 |
|
| 2008 |
Fuerer C, Nusse R, Ten Berge D. Wnt signalling in development and disease. Max Delbrück Center for Molecular Medicine meeting on Wnt signaling in Development and Disease. Embo Reports. 9: 134-8. PMID 18188179 DOI: 10.1038/sj.embor.7401159 |
1 |
|
| 2007 |
Hu M, Kurobe M, Jeong YJ, Fuerer C, Ghole S, Nusse R, Sylvester KG. Wnt/beta-catenin signaling in murine hepatic transit amplifying progenitor cells. Gastroenterology. 133: 1579-91. PMID 17983805 DOI: 10.1053/j.gastro.2007.08.036 |
1 |
|
| 2007 |
Fish MP, Groth AC, Calos MP, Nusse R. Creating transgenic Drosophila by microinjecting the site-specific phiC31 integrase mRNA and a transgene-containing donor plasmid. Nature Protocols. 2: 2325-31. PMID 17947973 DOI: 10.1038/nprot.2007.328 |
1 |
|
| 2007 |
Klapholz-Brown Z, Walmsley GG, Nusse YM, Nusse R, Brown PO. Transcriptional program induced by Wnt protein in human fibroblasts suggests mechanisms for cell cooperativity in defining tissue microenvironments. Plos One. 2: e945. PMID 17895986 DOI: 10.1371/journal.pone.0000945 |
1 |
|
| 2007 |
Brugmann SA, Goodnough LH, Gregorieff A, Leucht P, ten Berge D, Fuerer C, Clevers H, Nusse R, Helms JA. Wnt signaling mediates regional specification in the vertebrate face. Development (Cambridge, England). 134: 3283-95. PMID 17699607 DOI: 10.1242/dev.005132 |
1 |
|
| 2007 |
Kim JB, Leucht P, Lam K, Luppen C, Ten Berge D, Nusse R, Helms JA. Bone regeneration is regulated by wnt signaling. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 22: 1913-23. PMID 17696762 DOI: 10.1359/jbmr.070802 |
1 |
|
| 2007 |
Marino S, Nusse R. Mutants in the mouse NuRD/Mi2 component P66alpha are embryonic lethal. Plos One. 2: e519. PMID 17565372 DOI: 10.1371/journal.pone.0000519 |
1 |
|
| 2007 |
Nusse R. Cancer. Converging on beta-catenin in Wilms tumor. Science (New York, N.Y.). 316: 988-9. PMID 17510350 DOI: 10.1126/science.1143337 |
1 |
|
| 2007 |
Rulifson IC, Karnik SK, Heiser PW, ten Berge D, Chen H, Gu X, Taketo MM, Nusse R, Hebrok M, Kim SK. Wnt signaling regulates pancreatic beta cell proliferation. Proceedings of the National Academy of Sciences of the United States of America. 104: 6247-52. PMID 17404238 DOI: 10.1073/pnas.0701509104 |
1 |
|
| 2006 |
Mikels AJ, Nusse R. Wnts as ligands: processing, secretion and reception. Oncogene. 25: 7461-8. PMID 17143290 DOI: 10.1038/sj.onc.1210053 |
1 |
|
| 2006 |
Blitzer JT, Nusse R. A critical role for endocytosis in Wnt signaling. Bmc Cell Biology. 7: 28. PMID 16824228 DOI: 10.1186/1471-2121-7-28 |
1 |
|
| 2006 |
Gordon MD, Nusse R. Wnt signaling: multiple pathways, multiple receptors, and multiple transcription factors. The Journal of Biological Chemistry. 281: 22429-33. PMID 16793760 DOI: 10.1074/jbc.R600015200 |
1 |
|
| 2006 |
Wodarz A, Stewart DB, Nelson WJ, Nusse R. Wingless signaling modulates cadherin-mediated cell adhesion in Drosophila imaginal disc cells. Journal of Cell Science. 119: 2425-34. PMID 16720643 DOI: 10.1242/jcs.02973 |
1 |
|
| 2006 |
Ching W, Nusse R. A dedicated Wnt secretion factor. Cell. 125: 432-3. PMID 16678089 DOI: 10.1016/j.cell.2006.04.018 |
1 |
|
| 2006 |
Mikels AJ, Nusse R. Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context. Plos Biology. 4: e115. PMID 16602827 DOI: 10.1371/journal.pbio.0040115 |
1 |
|
| 2006 |
Galli LM, Barnes T, Cheng T, Acosta L, Anglade A, Willert K, Nusse R, Burrus LW. Differential inhibition of Wnt-3a by Sfrp-1, Sfrp-2, and Sfrp-3. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 235: 681-90. PMID 16425220 DOI: 10.1002/dvdy.20681 |
1 |
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| 2006 |
Kim JB, Leucht P, Lam K, Luppen CA, ten Berg D, Nusse R, Helms JA. Wnt signaling is essential for bone regeneration McB Molecular and Cellular Biomechanics. 3: 201. |
1 |
|
| 2005 |
Nusse R. Cell biology: relays at the membrane. Nature. 438: 747-9. PMID 16340998 DOI: 10.1038/438747a |
1 |
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| 2005 |
Povelones M, Nusse R. The role of the cysteine-rich domain of Frizzled in Wingless-Armadillo signaling. The Embo Journal. 24: 3493-503. PMID 16163385 DOI: 10.1038/sj.emboj.7600817 |
1 |
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| 2005 |
Gordon MD, Dionne MS, Schneider DS, Nusse R. WntD is a feedback inhibitor of Dorsal/NF-kappaB in Drosophila development and immunity. Nature. 437: 746-9. PMID 16107793 DOI: 10.1038/nature04073 |
1 |
|
| 2005 |
Povelones M, Howes R, Fish M, Nusse R. Genetic evidence that Drosophila frizzled controls planar cell polarity and Armadillo signaling by a common mechanism. Genetics. 171: 1643-54. PMID 16085697 DOI: 10.1534/genetics.105.045245 |
1 |
|
| 2005 |
Kon C, Cadigan KM, da Silva SL, Nusse R. Developmental roles of the Mi-2/NURD-associated protein p66 in Drosophila. Genetics. 169: 2087-100. PMID 15695365 DOI: 10.1534/genetics.104.034595 |
1 |
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| 2005 |
Nusse R. Wnt signaling in disease and in development. Cell Research. 15: 28-32. PMID 15686623 DOI: 10.1038/sj.cr.7290260 |
1 |
|
| 2004 |
Verras M, Brown J, Li X, Nusse R, Sun Z. Wnt3a growth factor induces androgen receptor-mediated transcription and enhances cell growth in human prostate cancer cells. Cancer Research. 64: 8860-6. PMID 15604245 DOI: 10.1158/0008-5472.CAN-04-2370 |
1 |
|
| 2004 |
Marino S, Romelfanger C, Yokota Y, Nusse R. Wnt1 is epistatic to Id2 in inducing mammary hyperplasia, ductal side-branching, and tumors in the mouse. Bmc Cancer. 4: 91. PMID 15601467 DOI: 10.1186/1471-2407-4-91 |
1 |
|
| 2004 |
Johnson ML, Harnish K, Nusse R, Van Hul W. LRP5 and Wnt signaling: a union made for bone. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 19: 1749-57. PMID 15476573 DOI: 10.1359/JBMR.040816 |
1 |
|
| 2004 |
Logan CY, Nusse R. The Wnt signaling pathway in development and disease. Annual Review of Cell and Developmental Biology. 20: 781-810. PMID 15473860 DOI: 10.1146/annurev.cellbio.20.010403.113126 |
1 |
|
| 2004 |
Groth AC, Fish M, Nusse R, Calos MP. Construction of transgenic Drosophila by using the site-specific integrase from phage phiC31. Genetics. 166: 1775-82. PMID 15126397 DOI: 10.1534/genetics.166.4.1775 |
1 |
|
| 2004 |
Galli LM, Willert K, Nusse R, Yablonka-Reuveni Z, Nohno T, Denetclaw W, Burrus LW. A proliferative role for Wnt-3a in chick somites. Developmental Biology. 269: 489-504. PMID 15110715 DOI: 10.1016/j.ydbio.2004.01.041 |
1 |
|
| 2004 |
Derksen PW, Tjin E, Meijer HP, Klok MD, MacGillavry HD, van Oers MH, Lokhorst HM, Bloem AC, Clevers H, Nusse R, van der Neut R, Spaargaren M, Pals ST. Illegitimate WNT signaling promotes proliferation of multiple myeloma cells. Proceedings of the National Academy of Sciences of the United States of America. 101: 6122-7. PMID 15067127 DOI: 10.1073/pnas.0305855101 |
1 |
|
| 2004 |
Nelson WJ, Nusse R. Convergence of Wnt, beta-catenin, and cadherin pathways. Science (New York, N.Y.). 303: 1483-7. PMID 15001769 DOI: 10.1126/science.1094291 |
1 |
|
| 2004 |
Kuhnert F, Davis CR, Wang HT, Chu P, Lee M, Yuan J, Nusse R, Kuo CJ. Essential requirement for Wnt signaling in proliferation of adult small intestine and colon revealed by adenoviral expression of Dickkopf-1. Proceedings of the National Academy of Sciences of the United States of America. 101: 266-71. PMID 14695885 DOI: 10.1073/pnas.2536800100 |
1 |
|
| 2003 |
Nusse R. Wnts and Hedgehogs: lipid-modified proteins and similarities in signaling mechanisms at the cell surface. Development (Cambridge, England). 130: 5297-305. PMID 14530294 DOI: 10.1242/dev.00821 |
1 |
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| 2003 |
Chen W, ten Berge D, Brown J, Ahn S, Hu LA, Miller WE, Caron MG, Barak LS, Nusse R, Lefkowitz RJ. Dishevelled 2 recruits beta-arrestin 2 to mediate Wnt5A-stimulated endocytosis of Frizzled 4. Science (New York, N.Y.). 301: 1391-4. PMID 12958364 DOI: 10.1126/science.1082808 |
1 |
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| 2003 |
Willert K, Brown JD, Danenberg E, Duncan AW, Weissman IL, Reya T, Yates JR, Nusse R. Wnt proteins are lipid-modified and can act as stem cell growth factors. Nature. 423: 448-52. PMID 12717451 DOI: 10.1038/nature01611 |
1 |
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| 2003 |
Reya T, Duncan AW, Ailles L, Domen J, Scherer DC, Willert K, Hintz L, Nusse R, Weissman IL. A role for Wnt signalling in self-renewal of haematopoietic stem cells. Nature. 423: 409-14. PMID 12717450 DOI: 10.1038/nature01593 |
1 |
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| 2002 |
Povelones M, Nusse R. Wnt signalling sees spots. Nature Cell Biology. 4: E249-50. PMID 12415278 DOI: 10.1038/ncb1102-e249 |
1 |
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| 2002 |
Yamazaki H, Nusse R. Identification of DCAP, a drosophila homolog of a glucose transport regulatory complex. Mechanisms of Development. 119: 115-9. PMID 12385759 DOI: 10.1016/S0925-4773(02)00307-6 |
1 |
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| 2002 |
Wu CH, Nusse R. Ligand receptor interactions in the Wnt signaling pathway in Drosophila. The Journal of Biological Chemistry. 277: 41762-9. PMID 12205098 DOI: 10.1074/jbc.M207850200 |
1 |
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| 2002 |
Willert J, Epping M, Pollack JR, Brown PO, Nusse R. A transcriptional response to Wnt protein in human embryonic carcinoma cells. Bmc Developmental Biology. 2: 8. PMID 12095419 |
1 |
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| 2002 |
Cadigan KM, Jou AD, Nusse R. Wingless blocks bristle formation and morphogenetic furrow progression in the eye through repression of Daughterless. Development (Cambridge, England). 129: 3393-402. PMID 12091309 |
1 |
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| 2002 |
Penton A, Wodarz A, Nusse R. A mutational analysis of dishevelled in Drosophila defines novel domains in the dishevelled protein as well as novel suppressing alleles of axin. Genetics. 161: 747-62. PMID 12072470 |
1 |
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| 2002 |
Rulifson EJ, Kim SK, Nusse R. Ablation of insulin-producing neurons in flies: growth and diabetic phenotypes. Science (New York, N.Y.). 296: 1118-20. PMID 12004130 DOI: 10.1126/science.1070058 |
1 |
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| 2002 |
Kozopas KM, Nusse R. Direct flight muscles in Drosophila develop from cells with characteristics of founders and depend on DWnt-2 for their correct patterning. Developmental Biology. 243: 312-25. PMID 11884040 DOI: 10.1006/dbio.2002.0572 |
1 |
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| 2001 |
Nusse R. An ancient cluster of Wnt paralogues. Trends in Genetics : Tig. 17: 443. PMID 11491115 |
1 |
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| 2001 |
Wilson SI, Rydström A, Trimborn T, Willert K, Nusse R, Jessell TM, Edlund T. The status of Wnt signalling regulates neural and epidermal fates in the chick embryo. Nature. 411: 325-30. PMID 11357137 DOI: 10.1038/35077115 |
0.36 |
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| 2001 |
Nusse R. Developmental biology. Making head or tail of Dickkopf. Nature. 411: 255-6. PMID 11357114 DOI: 10.1038/35077199 |
1 |
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| 2001 |
Rousset R, Mack JA, Wharton KA, Axelrod JD, Cadigan KM, Fish MP, Nusse R, Scott MP. Naked cuticle targets dishevelled to antagonize Wnt signal transduction. Genes & Development. 15: 658-71. PMID 11274052 DOI: 10.1101/gad.869201 |
1 |
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| 2001 |
Roberts RJ, Varmus HE, Ashburner M, Brown PO, Eisen MB, Khosla C, Kirschner M, Nusse R, Scott M, Wold B. Information access. Building a "GenBank" of the published literature. Science (New York, N.Y.). 291: 2318-9. PMID 11269300 |
1 |
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| 2000 |
Rulifson EJ, Wu CH, Nusse R. Pathway specificity by the bifunctional receptor frizzled is determined by affinity for wingless. Molecular Cell. 6: 117-26. PMID 10949033 |
1 |
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| 2000 |
Nusse R, Rulifson E, Fish M, Harryman-Samos C, Brink M, Wu CH, Cadigan K. Interactions between wingless and frizzled molecules in Drosophila. Ernst Schering Research Foundation Workshop. 1-11. PMID 10943301 |
1 |
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| 2000 |
Reya T, O'Riordan M, Okamura R, Devaney E, Willert K, Nusse R, Grosschedl R. Wnt signaling regulates B lymphocyte proliferation through a LEF-1 dependent mechanism. Immunity. 13: 15-24. PMID 10933391 |
1 |
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| 1999 |
Bhanot P, Fish M, Jemison JA, Nusse R, Nathans J, Cadigan KM. Frizzled and Dfrizzled-2 function as redundant receptors for Wingless during Drosophila embryonic development. Development (Cambridge, England). 126: 4175-86. PMID 10457026 |
1 |
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| 1999 |
Willert K, Logan CY, Arora A, Fish M, Nusse R. A Drosophila Axin homolog, Daxin, inhibits Wnt signaling. Development (Cambridge, England). 126: 4165-73. PMID 10457025 |
1 |
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| 1999 |
Willert K, Shibamoto S, Nusse R. Wnt-induced dephosphorylation of axin releases beta-catenin from the axin complex. Genes & Development. 13: 1768-73. PMID 10421629 |
1 |
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| 1999 |
Hsieh JC, Kodjabachian L, Rebbert ML, Rattner A, Smallwood PM, Samos CH, Nusse R, Dawid IB, Nathans J. A new secreted protein that binds to Wnt proteins and inhibits their activities. Nature. 398: 431-6. PMID 10201374 DOI: 10.1038/18899 |
1 |
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| 1999 |
Nusse R. WNT targets. Repression and activation. Trends in Genetics : Tig. 15: 1-3. PMID 10087922 DOI: 10.1016/S0168-9525(98)01634-5 |
1 |
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| 1999 |
Millar SE, Willert K, Salinas PC, Roelink H, Nusse R, Sussman DJ, Barsh GS. WNT signaling in the control of hair growth and structure. Developmental Biology. 207: 133-49. PMID 10049570 DOI: 10.1006/dbio.1998.9140 |
1 |
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| 1998 |
Wodarz A, Nusse R. Mechanisms of Wnt signaling in development. Annual Review of Cell and Developmental Biology. 14: 59-88. PMID 9891778 DOI: 10.1146/annurev.cellbio.14.1.59 |
1 |
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| 1998 |
Perrimon N, Nusse R. Highlights of the 1998 Wnt meeting, Cambridge, MA, January 9-11. Biochimica Et Biophysica Acta. 1377: R45-9. PMID 9659404 DOI: 10.1016/S0304-419X(98)00007-9 |
1 |
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| 1998 |
Xu YK, Nusse R. The Frizzled CRD domain is conserved in diverse proteins including several receptor tyrosine kinases. Current Biology : Cb. 8: R405-6. PMID 9637908 |
1 |
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| 1998 |
Cadigan KM, Fish MP, Rulifson EJ, Nusse R. Wingless repression of Drosophila frizzled 2 expression shapes the Wingless morphogen gradient in the wing. Cell. 93: 767-77. PMID 9630221 DOI: 10.1016/S0092-8674(00)81438-5 |
1 |
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| 1998 |
Kozopas KM, Samos CH, Nusse R. DWnt-2, a Drosophila Wnt gene required for the development of the male reproductive tract, specifies a sexually dimorphic cell fate. Genes & Development. 12: 1155-65. PMID 9553045 |
1 |
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| 1998 |
Willert K, Nusse R. Beta-catenin: a key mediator of Wnt signaling. Current Opinion in Genetics & Development. 8: 95-102. PMID 9529612 DOI: 10.1016/S0959-437X(98)80068-3 |
1 |
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| 1998 |
Lessing D, Nusse R. Expression of wingless in the Drosophila embryo: a conserved cis-acting element lacking conserved Ci-binding sites is required for patched-mediated repression. Development (Cambridge, England). 125: 1469-76. PMID 9502727 |
1 |
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| 1997 |
Nusse R, Samos CH, Brink M, Willert K, Cadigan KM, Wodarz A, Fish M, Rulifson E. Cell culture and whole animal approaches to understanding signaling by Wnt proteins in Drosophila. Cold Spring Harbor Symposia On Quantitative Biology. 62: 185-90. PMID 9598351 |
1 |
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| 1997 |
Cadigan KM, Nusse R. Wnt signaling: a common theme in animal development. Genes & Development. 11: 3286-305. PMID 9407023 |
1 |
|
| 1997 |
Willert K, Brink M, Wodarz A, Varmus H, Nusse R. Casein kinase 2 associates with and phosphorylates dishevelled Embo Journal. 16: 3089-3096. PMID 9214626 DOI: 10.1093/emboj/16.11.3089 |
1 |
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| 1997 |
Nusse R. A versatile transcriptional effector of wingless signaling Cell. 89: 321-323. PMID 9150130 DOI: 10.1016/S0092-8674(00)80210-X |
1 |
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| 1997 |
Wang YK, Samos CH, Peoples R, Pérez-Jurado LA, Nusse R, Francke U. A novel human homologue of the Drosophila frizzled wnt receptor gene binds wingless protein and is in the Williams syndrome deletion at 7q11.23. Human Molecular Genetics. 6: 465-72. PMID 9147651 DOI: 10.1093/hmg/6.3.465 |
1 |
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| 1997 |
Von Ohlen T, Lessing D, Nusse R, Hooper JE. Hedgehog signaling regulates transcription through cubitus interruptus, a sequence-specific DNA binding protein Proceedings of the National Academy of Sciences of the United States of America. 94: 2404-2409. PMID 9122207 DOI: 10.1073/pnas.94.6.2404 |
1 |
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| 1997 |
Cadigan KM, Nusse R. Wnt meeting 1996. Biochimica Et Biophysica Acta. 1332: R1-5. PMID 9061012 DOI: 10.1016/S0304-419X(96)00037-6 |
1 |
|
| 1996 |
Nusse R. Patching up hedgehog Nature. 384: 119-120. PMID 8906783 DOI: 10.1038/384119a0 |
1 |
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| 1996 |
Cadigan KM, Nusse R. wingless signaling in the Drosophila eye and embryonic epidermis. Development (Cambridge, England). 122: 2801-12. PMID 8787754 |
1 |
|
| 1996 |
Bhanot P, Brink M, Samos CH, Hsieh JC, Wang Y, Macke JP, Andrew D, Nathans J, Nusse R. A new member of the frizzled family from Drosophila functions as a Wingless receptor. Nature. 382: 225-30. PMID 8717036 DOI: 10.1038/382225a0 |
1 |
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| 1995 |
Fradkin LG, Noordermeer JN, Nusse R. The Drosophila Wnt protein DWnt-3 is a secreted glycoprotein localized on the axon tracts of the embryonic CNS Developmental Biology. 168: 202-213. PMID 7883074 DOI: 10.1006/dbio.1995.1072 |
1 |
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| 1995 |
Yanagawa SI, Van Leeuwen F, Wodarz A, Klingensmith J, Nusse R. The Dishevelled protein is modified by Wingless signaling in Drosophila Genes and Development. 9: 1087-1097. PMID 7744250 |
1 |
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| 1995 |
Noordermeer J, Klingensmith J, Nusse R. Differential requirements for segment polarity genes in wingless signaling Mechanisms of Development. 51: 145-155. PMID 7547463 DOI: 10.1016/0925-4773(95)00348-7 |
1 |
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| 1995 |
Van Leeuwen F, Nusse R. Oncogene activation and oncogene cooperation in MMTV-induced mouse mammary cancer Seminars in Cancer Biology. 6: 127-133. |
1 |
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| 1994 |
Klingensmith J, Nusse R, Perrimon N. The Drosophila segment polarity gene dishevelled encodes a novel protein required for response to the wingless signal Genes and Development. 8: 118-130. PMID 8288125 |
1 |
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| 1994 |
van Leeuwen F, Samos CH, Nusse R. Biological activity of soluble wingless protein in cultured Drosophila imaginal disc cells. Nature. 368: 342-4. PMID 8127369 DOI: 10.1038/368342a0 |
1 |
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| 1994 |
Salinas PC, Fletcher C, Copeland NG, Jenkins NA, Nusse R. Maintenance of Wnt-3 expression in Purkinje cells of the mouse cerebellum depends on interactions with granule cells Development. 120: 1277-1286. PMID 8026336 |
1 |
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| 1994 |
Sussman DJ, Klingensmith J, Salinas P, Adams PS, Nusse R, Perrimon N. Isolation and characterization of a mouse homolog of the Drosophila segment polarity gene dishevelled Developmental Biology. 166: 73-86. PMID 7958461 DOI: 10.1006/dbio.1994.1297 |
1 |
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| 1994 |
Noordermeer J, Klingensmith J, Perrimont N, Nusse R. Dishevelled and armadillo act in the wingless signalling pathway in Drosophila Nature. 367: 80-83. PMID 7906389 DOI: 10.1038/367080a0 |
1 |
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| 1994 |
Klingensmith J, Nusse R. Signaling by wingless in Drosophila Developmental Biology. 166: 396-414. PMID 7813765 DOI: 10.1006/dbio.1994.1325 |
1 |
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| 1994 |
Van den Heuvel M, Harriman-Samos C, Klingensmith J, Perrimon N, Nusse R. Corrigendum: Mutations in the segment polarity genes wingless and porcupine impair secretion of the wingless protein (The EMBO Journal, (1993) 12 (5293-5302)) Embo Journal. 13: 2950. |
1 |
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| 1993 |
Van Heuvel MD, Harryman-Samos C, Klingensmith J, Perrimon N, Nusse R. Mutations in the segment polarity genes wingless and porcupine impair secretion of the wingless protein Embo Journal. 12: 5293-5302. PMID 8262072 |
1 |
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| 1993 |
Roelink H, Wang J, Black DM, Solomon E, Nusse R. Molecular cloning and chromosomal localization to 17q21 of the human WNT3 gene. Genomics. 17: 790-2. PMID 8244403 DOI: 10.1006/geno.1993.1412 |
1 |
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| 1993 |
van den Heuvel M, Klingensmith J, Perrimon N, Nusse R. Cell patterning in the Drosophila segment: engrailed and wingless antigen distributions in segment polarity mutant embryos Development (Cambridge, England). Supplement. 105-114. PMID 8049466 |
1 |
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| 1992 |
Nusse R, Varmus HE. Wnt genes. Cell. 69: 1073-87. PMID 1617723 DOI: 10.1016/0092-8674(92)90630-U |
1 |
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| 1992 |
Roelink H, Wagenaar E, Nusse R. Amplification and proviral activation of several Wnt genes during progression and clonal variation of mouse mammary tumors. Oncogene. 7: 487-92. PMID 1549363 |
1 |
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| 1992 |
Russell J, Gennissen A, Nusse R. Isolation and expression of two novel Wnt/wingless gene homologues in Drosophila Development. 115: 475-485. PMID 1425336 |
1 |
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| 1992 |
Nusse R. The Wnt gene family in tumorigenesis and in normal development Journal of Steroid Biochemistry and Molecular Biology. 43: 9-12. PMID 1388050 DOI: 10.1016/0960-0760(92)90181-H |
1 |
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| 1992 |
Salinas PC, Nusse R. Regional expression of the Wnt-3 gene in the developing mouse forebrain in relationship to diencephalic neuromeres Mechanisms of Development. 39: 151-160. PMID 1363370 DOI: 10.1016/0925-4773(92)90042-I |
1 |
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| 1992 |
Noordermeer J, Johnston P, Rijsewijk F, Nusse R, Lawrence PA. The consequences of ubiquitous expression of the wingless gene in the Drosophila embryo Development. 116: 711-719. PMID 1289061 |
1 |
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| 1991 |
Van de Vijver MJ, Nusse R. The molecular biology of breast cancer Bba - Reviews On Cancer. 1072: 33-50. PMID 2018777 DOI: 10.1016/0304-419X(91)90005-6 |
1 |
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| 1991 |
Roelink H, Nusse R. Expression of two members of the Wnt family during mouse development--restricted temporal and spatial patterns in the developing neural tube. Genes & Development. 5: 381-8. PMID 2001840 |
1 |
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| 1991 |
Nusse R, Brown A, Papkoff J, Scambler P, Shackleford G, McMahon A, Moon R, Varmus H. A new nomenclature for int-1 and related genes: The Wnt gene family Cell. 64: 231. PMID 1846319 DOI: 10.1016/0092-8674(91)90633-A |
1 |
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| 1991 |
Rajewsky MF, Birchmeier W, Cavalli F, Garattini S, Heldin CH, Mach JP, Monier R, Nusse R, Ponder BAJ, Riethmuller G, Tubiani M, Hansen HH, Aapro MS, Double JA, Gunzburg WH, et al. Towards improved cancer diagnosis and treatment founded on current developments in the basic sciences: Options for intensified European efforts European Journal of Cancer. 27: 936-939. PMID 1834132 DOI: 10.1016/0277-5379(91)90151-3 |
1 |
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| 1991 |
Nusse R. Insertional mutagenesis in mouse mammary tumorigenesis Current Topics in Microbiology and Immunology. 171: 44-65. PMID 1667629 |
1 |
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| 1990 |
Schuuring E, Van der Leede BJ, Willems R, Daams H, Van der Valk M, Van de Vijver M, Van Leeuwen F, Sonnenberg A, Nusse R. Differentiation-dependent expression of provirus-activated int-1 oncogen in clonal cell lines derived from a mouse mammary tumor Oncogene. 5: 459-465. PMID 2326076 |
1 |
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| 1990 |
Nusse R. The int genes in mouse mammary tumorigenesis and in normal development Ciba Foundation Symposium. 150: 212-222; discussion . PMID 2164908 |
1 |
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| 1990 |
Roelink H, Wagenaar E, Lopes da Silva S, Nusse R. Wnt-3, a gene activated by proviral insertion in mouse mammary tumors, is homologous to int-1/Wnt-1 and is normally expressed in mouse embryos and adult brain. Proceedings of the National Academy of Sciences of the United States of America. 87: 4519-23. PMID 2162045 DOI: 10.1073/pnas.87.12.4519 |
1 |
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| 1990 |
Van Leeuwen F, Van De Vijver MJ, Lomans J, Van Deemter L, Jenster G, Akiyama T, Yamamoto T, Nusse R. Mutation of the human neu protein facilitates down-modulation by monoclonal antibodies Oncogene. 5: 497-503. PMID 1970152 |
1 |
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| 1990 |
Nusse R, Theunissen H, Wagenaar E, Rijsewijk F, Gennissen A, Otte A, Schuuring E, van Ooyen A. The Wnt-1 (int-1) oncogene promoter and its mechanism of activation by insertion of proviral DNA of the mouse mammary tumor virus. Molecular and Cellular Biology. 10: 4170-9. PMID 1695322 |
1 |
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| 1989 |
Schuuring E, van Deemter L, Roelink H, Nusse R. Transient expression of the proto-oncogene int-1 during differentiation of P19 embryonal carcinoma cells. Molecular and Cellular Biology. 9: 1357-61. PMID 2657391 |
1 |
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| 1989 |
van den Heuvel M, Nusse R, Johnston P, Lawrence PA. Distribution of the wingless gene product in drosophila embryos: A protein involved in cell-cell communication Cell. 59: 739-749. PMID 2582493 DOI: 10.1016/0092-8674(89)90020-2 |
1 |
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| 1989 |
Theunissen HJM, Paardekooper M, Maduro LJ, Michalides RJAM, Nusse R. Phorbol ester-inducible T-cell-specific expression of variant mouse mammary tumor virus long terminal repeats Journal of Virology. 63: 3466-3471. PMID 2545916 |
1 |
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| 1988 |
Van de Vijver MJ, Mooi WJ, Peterse JL, Nusse R. Amplification and over-expression of the neu oncogene in human breast carcinomas European Journal of Surgical Oncology. 14: 111-114. PMID 3360152 |
1 |
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| 1988 |
Van De Vijver MJ, Mooi WJ, Wisman P, Peterse JL, Nusse R. Immunohistochemical detection of the neu protein in tissue sections of human breast tumors with amplified neu DNA Oncogene. 2: 175-178. PMID 3285295 |
1 |
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| 1988 |
Nusse R. The int genes in mammary tumorigenesis and in normal development Trends in Genetics. 4: 291-295. PMID 3076290 DOI: 10.1016/0168-9525(88)90172-2 |
1 |
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| 1988 |
Nusse R. The activation of cellular oncogenes by proviral insertion in murine mammary cancer Cancer Treatment and Research. 40: 283-306. PMID 2908657 |
1 |
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| 1988 |
Van de Vijver MJ, Peterse JL, Mooi WJ, Wisman P, Lomans J, Dalesio O, Nusse R. Neu-protein overexpression in breast cancer. Association with comedo-type ductal carcinoma in situ and limited prognostic value in Stage II breast cancer New England Journal of Medicine. 319: 1239-1245. PMID 2903446 |
1 |
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| 1987 |
van de Vijver M, van de Bersselaar R, Devilee P, Cornelisse C, Peterse J, Nusse R. Amplification of the neu (c-erbB-2) oncogene in human mammary tumors is relatively frequent and is often accompanied by amplification of the linked c-erbA oncogene Molecular and Cellular Biology. 7: 2019-2023. PMID 3299059 |
1 |
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| 1987 |
Rijsewijk F, Schuermann M, Wagenaar E, Parren P, Weigel D, Nusse R. The Drosophila homology of the mouse mammary oncogene int-1 is identical to the segment polarity gene wingless Cell. 50: 649-657. PMID 3111720 DOI: 10.1016/0092-8674(87)90038-9 |
1 |
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| 1987 |
Rijsewijk F, van Deemter L, Wagenaar E, Sonnenberg A, Nusse R. Transfection of the int-1 mammary oncogene in cuboidal RAC mammary cell line results in morphological transformation and tumorigenicity Embo Journal. 6: 127-131. PMID 3034569 |
1 |
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| 1987 |
Sonnenberg A, van Balen P, Hilgers J, Schuuring E, Nusse R. Oncogene expression during progression of mouse mammary tumor cells; activity of a proviral enhancer and the resulting expression of int-2 is influenced by the state of differentiation Embo Journal. 6: 121-125. PMID 3034568 |
1 |
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| 1987 |
Mester J, Wagenaar E, Sluyser M, Nusse R. Activation of int-1 and int-2 mammary oncogenes in hormone-dependent and -independent mammary tumors of GR mice Journal of Virology. 61: 1073-1078. PMID 3029401 |
1 |
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| 1986 |
Lens PF, Altena B, Nusse R. Expression of c-sis and platelet-derived growth factor in in vitro-transformed glioma cells from rat brain tissue transplacentally treated with ethylnitrosourea Molecular and Cellular Biology. 6: 3537-3540. PMID 3540593 |
1 |
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| 1986 |
Rijsewijk FA, van Lohuizen M, van Ooyen A, Nusse R. Construction of a retroviral cDNA version of the int-1 mammary oncogene and its expression in vitro. Nucleic Acids Research. 14: 693-702. PMID 3003692 |
1 |
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| 1986 |
Nusse R. The activation of cellular oncogenes by retroviral insertion Trends in Genetics. 2: 244-247. DOI: 10.1016/0168-9525(86)90247-7 |
1 |
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| 1985 |
Janssen JWG, Steenvoorden ACM, Collard JG, Nusse R. Oncogene activation in human myeloid leukemia Cancer Research. 45: 3262-3267. PMID 3859367 |
1 |
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| 1985 |
van Ooyen A, Kwee V, Nusse R. The nucleotide sequence of the human int-1 mammary oncogene; evolutionary conservation of coding and non-coding sequences. The Embo Journal. 4: 2905-9. PMID 2998762 |
1 |
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| 1985 |
Geurts van Kessel A, Nusse R, Slater R, Tetteroo P, Hagemeijer A. Localization of the oncogene c-Ha-ras1 outside the aniridia-Wilms' tumor-associated deletion of chromosome 11(del 11p13) using somatic cell hybrids Cancer Genetics and Cytogenetics. 15: 79-84. PMID 2981609 DOI: 10.1016/0165-4608(85)90132-3 |
1 |
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| 1985 |
Nusse R, van Ooyen A, Rijsewijk F, van Lohuizen M, Schuuring E, van't Veer L. Retroviral insertional mutagenesis in murine mammary cancer. Proceedings of the Royal Society of London. Series B, Biological Sciences. 226: 3-13. PMID 2866522 |
1 |
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| 1984 |
Nusse R, van Ooyen A, Cox D, Fung YK, Varmus H. Mode of proviral activation of a putative mammary oncogene (int-1) on mouse chromosome 15. Nature. 307: 131-6. PMID 6318122 DOI: 10.1038/307131a0 |
1 |
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| 1984 |
van Ooyen A, Nusse R. Structure and nucleotide sequence of the putative mammary oncogene int-1; proviral insertions leave the protein-encoding domain intact. Cell. 39: 233-40. PMID 6091914 DOI: 10.1016/0092-8674(84)90209-5 |
1 |
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| 1983 |
Michalides R, van Ooyen A, Nusse R. Mouse mammary tumor virus expression and mammary tumor development. Current Topics in Microbiology and Immunology. 106: 57-78. PMID 6315307 |
1 |
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| 1983 |
van Ooyen AJ, Michalides RJ, Nusse R. Structural analysis of a 1.7-kilobase mouse mammary tumor virus-specific RNA. Journal of Virology. 46: 362-70. PMID 6188860 |
1 |
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| 1982 |
Nusse R, Varmus HE. Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome Cell. 31: 99-109. PMID 6297757 DOI: 10.1016/0092-8674(82)90409-3 |
1 |
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| 1981 |
E. Hynes N, Rahmsdorf U, Kennedy N, Fabiani L, Michalides R, Nusse R, Groner B. Structure, stability, methylation, expression and glucocorticoid induction of endogenous and transfected proviral genes of mouse mammary tumor virus in mouse fibroblasts Gene. 15: 307-317. PMID 6277735 DOI: 10.1016/0378-1119(81)90174-8 |
1 |
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| 1981 |
Michalides R, van Nie R, Nusse R, Hynes NE, Groner B. Mammary tumor induction loci in GR and DBAf mice contain one provirus of the mouse mammary tumor virus Cell. 23: 165-173. PMID 6260372 DOI: 10.1016/0092-8674(81)90281-6 |
1 |
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| 1980 |
Nusse R, Janssen H, De Vries L, Michalides R. Analysis of secondary modifications of mouse mammary tumor virus proteins by two-dimensional gel electrophoresis Journal of Virology. 35: 340-348. PMID 6255175 |
1 |
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| 1980 |
Hilgers J, Sonnenberg A, Nusse R. Antigenic modulation of mammary tumour virus envelope antigen on GR thymic lymphoma cells in relation to expression of H-2, TL cell-surface antigens and Thy1 British Journal of Cancer. 42: 542-550. PMID 6254554 |
1 |
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| 1980 |
Nusse R, De Moes J, Hilkens J, Van Nie R. Localization of a gene for expression of mouse mammary tumor virus antigens in the GR/Mtv-2- mouse strain Journal of Experimental Medicine. 152: 712-718. PMID 6251153 |
1 |
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| 1980 |
Nusse R, Michalides R, Boot LM, Ropcke G. Quantification of mouse mammary tumor virus structural proteins in hormone-induced mammary tumors of low mammary tumor mouse strains International Journal of Cancer. 25: 377-383. PMID 6248469 |
1 |
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| 1979 |
Snoek M, Iványi D, Nusse R, Démant P. A new H-2.1-Positive D region allele, Ddx, controlling two molecules, H-2Ddx and H-2Ldx Immunogenetics. 8: 109-125. DOI: 10.1007/BF01561421 |
1 |
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