Kevin Struhl - Publications

Affiliations: 
Biological Chemistry and Molecular Pharmacology Harvard Medical School, Boston, MA, United States 
Area:
Transcription
Website:
https://struhl.med.harvard.edu/

212 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Moqtaderi Z, Geisberg JV, Struhl K. Extensive Structural Differences of Closely Related 3' mRNA Isoforms: Links to Pab1 Binding and mRNA Stability. Molecular Cell. PMID 30318446 DOI: 10.1016/j.molcel.2018.08.044  0.48
2016 Miotto B, Ji Z, Struhl K. Selectivity of ORC binding sites and the relation to replication timing, fragile sites, and deletions in cancers. Proceedings of the National Academy of Sciences of the United States of America. PMID 27436900 DOI: 10.1073/pnas.1609060113  1
2016 Ji Z, Song R, Huang H, Regev A, Struhl K. Transcriptome-scale RNase-footprinting of RNA-protein complexes. Nature Biotechnology. PMID 26900662 DOI: 10.1038/nbt.3441  1
2015 Rotem A, Janzer A, Izar B, Ji Z, Doench JG, Garraway LA, Struhl K. Alternative to the soft-agar assay that permits high-throughput drug and genetic screens for cellular transformation. Proceedings of the National Academy of Sciences of the United States of America. 112: 5708-13. PMID 25902495 DOI: 10.1073/pnas.1505979112  1
2015 Jin Y, Geisberg JV, Moqtaderi Z, Ji Z, Hoque M, Tian B, Struhl K. Mapping 3' mRNA isoforms on a genomic scale. Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. 110: 4.23.1-4.23.17. PMID 25827089 DOI: 10.1002/0471142727.mb0423s110  1
2015 Fleming JD, Giresi PG, Lindahl-Allen M, Krall EB, Lieb JD, Struhl K. STAT3 acts through pre-existing nucleosome-depleted regions bound by FOS during an epigenetic switch linking inflammation to cancer. Epigenetics & Chromatin. 8: 7. PMID 25784959 DOI: 10.1186/1756-8935-8-7  1
2014 Moqtaderi Z, Geisberg JV, Struhl K. Secondary structures involving the poly(A) tail and other 3' sequences are major determinants of mRNA isoform stability in yeast. Microbial Cell. 1: 137-139. PMID 25279376  0.48
2014 Janzer A, German NJ, Gonzalez-Herrera KN, Asara JM, Haigis MC, Struhl K. Metformin and phenformin deplete tricarboxylic acid cycle and glycolytic intermediates during cell transformation and NTPs in cancer stem cells. Proceedings of the National Academy of Sciences of the United States of America. 111: 10574-9. PMID 25002509 DOI: 10.1073/pnas.1409844111  1
2014 Wong KH, Jin Y, Struhl K. TFIIH phosphorylation of the Pol II CTD stimulates mediator dissociation from the preinitiation complex and promoter escape. Molecular Cell. 54: 601-12. PMID 24746699 DOI: 10.1016/j.molcel.2014.03.024  1
2014 Struhl K. Is DNA methylation of tumour suppressor genes epigenetic? Elife. 3: e02475. PMID 24623307 DOI: 10.7554/eLife.02475  1
2014 Geisberg JV, Moqtaderi Z, Fan X, Ozsolak F, Struhl K. Global analysis of mRNA isoform half-lives reveals stabilizing and destabilizing elements in yeast. Cell. 156: 812-24. PMID 24529382 DOI: 10.1016/j.cell.2013.12.026  1
2013 Moqtaderi Z, Geisberg JV, Jin Y, Fan X, Struhl K. Species-specific factors mediate extensive heterogeneity of mRNA 3' ends in yeasts. Proceedings of the National Academy of Sciences of the United States of America. 110: 11073-8. PMID 23776204 DOI: 10.1073/pnas.1309384110  1
2013 Fleming JD, Pavesi G, Benatti P, Imbriano C, Mantovani R, Struhl K. NF-Y coassociates with FOS at promoters, enhancers, repetitive elements, and inactive chromatin regions, and is stereo-positioned with growth-controlling transcription factors. Genome Research. 23: 1195-209. PMID 23595228 DOI: 10.1101/gr.148080.112  1
2013 Struhl K, Segal E. Determinants of nucleosome positioning. Nature Structural & Molecular Biology. 20: 267-73. PMID 23463311 DOI: 10.1038/nsmb.2506  1
2013 Hirsch HA, Iliopoulos D, Struhl K. Metformin inhibits the inflammatory response associated with cellular transformation and cancer stem cell growth. Proceedings of the National Academy of Sciences of the United States of America. 110: 972-7. PMID 23277563 DOI: 10.1073/pnas.1221055110  1
2012 Hughes AL, Jin Y, Rando OJ, Struhl K. A functional evolutionary approach to identify determinants of nucleosome positioning: a unifying model for establishing the genome-wide pattern. Molecular Cell. 48: 5-15. PMID 22885008 DOI: 10.1016/j.molcel.2012.07.003  1
2012 Barber MF, Michishita-Kioi E, Xi Y, Tasselli L, Kioi M, Moqtaderi Z, Tennen RI, Paredes S, Young NL, Chen K, Struhl K, Garcia BA, Gozani O, Li W, Chua KF. SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation. Nature. 487: 114-8. PMID 22722849 DOI: 10.1038/nature11043  1
2012 Yuan CC, Matthews AG, Jin Y, Chen CF, Chapman BA, Ohsumi TK, Glass KC, Kutateladze TG, Borowsky ML, Struhl K, Oettinger MA. Histone H3R2 symmetric dimethylation and histone H3K4 trimethylation are tightly correlated in eukaryotic genomes. Cell Reports. 1: 83-90. PMID 22720264 DOI: 10.1016/j.celrep.2011.12.008  1
2012 Lee JJ, Drakaki A, Iliopoulos D, Struhl K. MiR-27b targets PPARγ to inhibit growth, tumor progression and the inflammatory response in neuroblastoma cells. Oncogene. 31: 3818-25. PMID 22120719 DOI: 10.1038/onc.2011.543  1
2011 Wong KH, Struhl K. The Cyc8-Tup1 complex inhibits transcription primarily by masking the activation domain of the recruiting protein. Genes & Development. 25: 2525-39. PMID 22156212 DOI: 10.1101/gad.179275.111  1
2011 Hatziapostolou M, Polytarchou C, Aggelidou E, Drakaki A, Poultsides GA, Jaeger SA, Ogata H, Karin M, Struhl K, Hadzopoulou-Cladaras M, Iliopoulos D. An HNF4α-miRNA inflammatory feedback circuit regulates hepatocellular oncogenesis. Cell. 147: 1233-47. PMID 22153071 DOI: 10.1016/j.cell.2011.10.043  1
2011 Krebs AR, Karmodiya K, Lindahl-Allen M, Struhl K, Tora L. SAGA and ATAC histone acetyl transferase complexes regulate distinct sets of genes and ATAC defines a class of p300-independent enhancers. Molecular Cell. 44: 410-23. PMID 22055187 DOI: 10.1016/j.molcel.2011.08.037  1
2011 Tirosh I, Wong KH, Barkai N, Struhl K. Extensive divergence of yeast stress responses through transitions between induced and constitutive activation. Proceedings of the National Academy of Sciences of the United States of America. 108: 16693-8. PMID 21930916 DOI: 10.1073/pnas.1113718108  1
2011 Miotto B, Struhl K. JNK1 phosphorylation of Cdt1 inhibits recruitment of HBO1 histone acetylase and blocks replication licensing in response to stress. Molecular Cell. 44: 62-71. PMID 21856198 DOI: 10.1016/j.molcel.2011.06.021  1
2011 Esberg A, Moqtaderi Z, Fan X, Lu J, Struhl K, Byström A. Iwr1 protein is important for preinitiation complex formation by all three nuclear RNA polymerases in Saccharomyces cerevisiae. Plos One. 6: e20829. PMID 21695216 DOI: 10.1371/journal.pone.0020829  1
2011 Iliopoulos D, Rotem A, Struhl K. Inhibition of miR-193a expression by Max and RXRα activates K-Ras and PLAU to mediate distinct aspects of cellular transformation. Cancer Research. 71: 5144-53. PMID 21670079 DOI: 10.1158/0008-5472.CAN-11-0425  1
2011 Polytarchou C, Iliopoulos D, Hatziapostolou M, Kottakis F, Maroulakou I, Struhl K, Tsichlis PN. Akt2 regulates all Akt isoforms and promotes resistance to hypoxia through induction of miR-21 upon oxygen deprivation. Cancer Research. 71: 4720-31. PMID 21555366 DOI: 10.1158/0008-5472.CAN-11-0365  1
2011 Iliopoulos D, Hirsch HA, Struhl K. Metformin decreases the dose of chemotherapy for prolonging tumor remission in mouse xenografts involving multiple cancer cell types. Cancer Research. 71: 3196-201. PMID 21415163 DOI: 10.1158/0008-5472.CAN-10-3471  1
2011 Iliopoulos D, Hirsch HA, Wang G, Struhl K. Inducible formation of breast cancer stem cells and their dynamic equilibrium with non-stem cancer cells via IL6 secretion. Proceedings of the National Academy of Sciences of the United States of America. 108: 1397-402. PMID 21220315 DOI: 10.1073/pnas.1018898108  1
2011 Katan-Khaykovich Y, Struhl K. Splitting of H3-H4 tetramers at transcriptionally active genes undergoing dynamic histone exchange. Proceedings of the National Academy of Sciences of the United States of America. 108: 1296-301. PMID 21220302 DOI: 10.1073/pnas.1018308108  1
2010 Locke G, Tolkunov D, Moqtaderi Z, Struhl K, Morozov AV. High-throughput sequencing reveals a simple model of nucleosome energetics. Proceedings of the National Academy of Sciences of the United States of America. 107: 20998-1003. PMID 21084631 DOI: 10.1073/pnas.1003838107  1
2010 Fan X, Moqtaderi Z, Jin Y, Zhang Y, Liu XS, Struhl K. Nucleosome depletion at yeast terminators is not intrinsic and can occur by a transcriptional mechanism linked to 3'-end formation. Proceedings of the National Academy of Sciences of the United States of America. 107: 17945-50. PMID 20921369 DOI: 10.1073/pnas.1012674107  1
2010 Iliopoulos D, Lindahl-Allen M, Polytarchou C, Hirsch HA, Tsichlis PN, Struhl K. Loss of miR-200 inhibition of Suz12 leads to polycomb-mediated repression required for the formation and maintenance of cancer stem cells. Molecular Cell. 39: 761-72. PMID 20832727 DOI: 10.1016/j.molcel.2010.08.013  1
2010 Iliopoulos D, Jaeger SA, Hirsch HA, Bulyk ML, Struhl K. STAT3 activation of miR-21 and miR-181b-1 via PTEN and CYLD are part of the epigenetic switch linking inflammation to cancer. Molecular Cell. 39: 493-506. PMID 20797623 DOI: 10.1016/j.molcel.2010.07.023  1
2010 Zhang Y, Moqtaderi Z, Rattner BP, Euskirchen G, Snyder M, Kadonaga JT, Liu XS, Struhl K. Evidence against a genomic code for nucleosome positioning. Reply to "Nucleosome sequence preferences influence in vivo nucleosome organization.". Nature Structural & Molecular Biology. 17: 920-3. PMID 20683474 DOI: 10.1038/nsmb0810-920  0.48
2010 Yang A, Zhu Z, Kettenbach A, Kapranov P, McKeon F, Gingeras TR, Struhl K. Genome-wide mapping indicates that p73 and p63 co-occupy target sites and have similar dna-binding profiles in vivo. Plos One. 5: e11572. PMID 20644729 DOI: 10.1371/journal.pone.0011572  1
2010 Moqtaderi Z, Wang J, Raha D, White RJ, Snyder M, Weng Z, Struhl K. Genomic binding profiles of functionally distinct RNA polymerase III transcription complexes in human cells. Nature Structural & Molecular Biology. 17: 635-40. PMID 20418883 DOI: 10.1038/nsmb.1794  1
2010 Hirsch HA, Iliopoulos D, Joshi A, Zhang Y, Jaeger SA, Bulyk M, Tsichlis PN, Shirley Liu X, Struhl K. A transcriptional signature and common gene networks link cancer with lipid metabolism and diverse human diseases. Cancer Cell. 17: 348-61. PMID 20385360 DOI: 10.1016/j.ccr.2010.01.022  1
2010 Raha D, Wang Z, Moqtaderi Z, Wu L, Zhong G, Gerstein M, Struhl K, Snyder M. Close association of RNA polymerase II and many transcription factors with Pol III genes. Proceedings of the National Academy of Sciences of the United States of America. 107: 3639-44. PMID 20139302 DOI: 10.1073/pnas.0911315106  1
2010 Miotto B, Struhl K. HBO1 histone acetylase activity is essential for DNA replication licensing and inhibited by Geminin. Molecular Cell. 37: 57-66. PMID 20129055 DOI: 10.1016/j.molcel.2009.12.012  1
2010 Zhang Y, Moqtaderi Z, Rattner BP, Euskirchen G, Snyder M, Kadonaga JT, Liu XS, Struhl K. Reply to Evidence against a genomic code for nucleosome positioning Nature Structural and Molecular Biology. 17: 920-923. DOI: 10.1038/nsmb0810-920  1
2010 Ausubel FM, Brent R, Kingston RE, Moore DD, Seidman JG, Smith JA, Struhl K. Current Protocols in Molecular Biology: Preface Current Protocols in Molecular Biology. iii-v. DOI: 10.1002/0471142727.mbprefs66  1
2010 Lundblad V, Struhl K. Yeast: Introduction Current Protocols in Molecular Biology. 13.0.1-13.0.4. DOI: 10.1002/0471142727.mb1300s82  1
2009 Iliopoulos D, Hirsch HA, Struhl K. An epigenetic switch involving NF-kappaB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation. Cell. 139: 693-706. PMID 19878981 DOI: 10.1016/j.cell.2009.10.014  1
2009 Iliopoulos D, Polytarchou C, Hatziapostolou M, Kottakis F, Maroulakou IG, Struhl K, Tsichlis PN. MicroRNAs differentially regulated by Akt isoforms control EMT and stem cell renewal in cancer cells. Science Signaling. 2: ra62. PMID 19825827 DOI: 10.1126/scisignal.2000356  1
2009 Hirsch HA, Iliopoulos D, Tsichlis PN, Struhl K. Metformin selectively targets cancer stem cells, and acts together with chemotherapy to block tumor growth and prolong remission. Cancer Research. 69: 7507-11. PMID 19752085 DOI: 10.1158/0008-5472.CAN-09-2994  1
2009 Auerbach RK, Euskirchen G, Rozowsky J, Lamarre-Vincent N, Moqtaderi Z, Lefrançois P, Struhl K, Gerstein M, Snyder M. Mapping accessible chromatin regions using Sono-Seq. Proceedings of the National Academy of Sciences of the United States of America. 106: 14926-31. PMID 19706456 DOI: 10.1073/pnas.0905443106  1
2009 Zhang Y, Moqtaderi Z, Rattner BP, Euskirchen G, Snyder M, Kadonaga JT, Liu XS, Struhl K. Intrinsic histone-DNA interactions are not the major determinant of nucleosome positions in vivo. Nature Structural & Molecular Biology. 16: 847-52. PMID 19620965 DOI: 10.1038/nsmb.1636  1
2009 Fan X, Struhl K. Where does mediator bind in vivo? Plos One. 4: e5029. PMID 19343176 DOI: 10.1371/journal.pone.0005029  1
2009 Hirsch HA, Iliopoulos D, Tsichlis PN, Struhl K. Metformin selectively targets cancer stem cells, and acts together with chemotherapy to block tumor growth and prolong remission (Cancer Research (2009) 69, (7507-7511)) Cancer Research. 69: 8832. DOI: 10.1158/0008-5472.CAN-09-3869  1
2009 Struhl K. Enzymatic manipulation of DNA and RNA Current Protocols in Molecular Biology. 3.0.1-3.0.2. DOI: 10.1002/0471142727.mb0300s86  1
2008 Struhl K. The hisB463 mutation and expression of a eukaryotic protein in Escherichia coli. Genetics. 180: 709-14. PMID 18927256 DOI: 10.1534/genetics.104.96693  1
2008 Madhani HD, Francis NJ, Kingston RE, Kornberg RD, Moazed D, Narlikar GJ, Panning B, Struhl K. Epigenomics: a roadmap, but to where? Science (New York, N.Y.). 322: 43-4. PMID 18832628 DOI: 10.1126/science.322.5898.43b  1
2008 Miotto B, Struhl K. HBO1 histone acetylase is a coactivator of the replication licensing factor Cdt1. Genes & Development. 22: 2633-8. PMID 18832067 DOI: 10.1101/gad.1674108  1
2008 Fan X, Lamarre-Vincent N, Wang Q, Struhl K. Extensive chromatin fragmentation improves enrichment of protein binding sites in chromatin immunoprecipitation experiments. Nucleic Acids Research. 36: e125. PMID 18765474 DOI: 10.1093/nar/gkn535  1
2008 Thakur JK, Arthanari H, Yang F, Pan SJ, Fan X, Breger J, Frueh DP, Gulshan K, Li DK, Mylonakis E, Struhl K, Moye-Rowley WS, Cormack BP, Wagner G, Näär AM. A nuclear receptor-like pathway regulating multidrug resistance in fungi. Nature. 452: 604-9. PMID 18385733 DOI: 10.1038/nature06836  1
2008 Moqtaderi Z, Struhl K. Expanding the repertoire of plasmids for PCR-mediated epitope tagging in yeast. Yeast (Chichester, England). 25: 287-92. PMID 18338317 DOI: 10.1002/yea.1581  1
2008 Wade JT, Struhl K. The transition from transcriptional initiation to elongation. Current Opinion in Genetics & Development. 18: 130-6. PMID 18282700 DOI: 10.1016/j.gde.2007.12.008  1
2008 Johnson DS, Li W, Gordon DB, Bhattacharjee A, Curry B, Ghosh J, Brizuela L, Carroll JS, Brown M, Flicek P, Koch CM, Dunham I, Bieda M, Xu X, Farnham PJ, ... ... Struhl K, et al. Systematic evaluation of variability in ChIP-chip experiments using predefined DNA targets. Genome Research. 18: 393-403. PMID 18258921 DOI: 10.1101/gr.7080508  1
2008 Struhl K. Kevin Struhl. Interview. Current Biology : Cb. 18: R7-9. PMID 18228638 DOI: 10.1016/j.cub.2007.10.060  1
2007 Ghosh S, Hirsch HA, Sekinger EA, Kapranov P, Struhl K, Gingeras TR. Differential analysis for high density tiling microarray data. Bmc Bioinformatics. 8: 359. PMID 17892592 DOI: 10.1186/1471-2105-8-359  1
2007 Miotto B, Struhl K. [Histone H4 lysine 16 acetylation: from genome regulation to tumoral progression]. MéDecine Sciences : M/S. 23: 735-40. PMID 17875292 DOI: 10.1051/medsci/20072389735  1
2007 Schwabish MA, Struhl K. The Swi/Snf complex is important for histone eviction during transcriptional activation and RNA polymerase II elongation in vivo. Molecular and Cellular Biology. 27: 6987-95. PMID 17709398 DOI: 10.1128/MCB.00717-07  1
2007 Peckham HE, Thurman RE, Fu Y, Stamatoyannopoulos JA, Noble WS, Struhl K, Weng Z. Nucleosome positioning signals in genomic DNA. Genome Research. 17: 1170-7. PMID 17620451 DOI: 10.1101/gr.6101007  1
2007 Wade JT, Struhl K, Busby SJ, Grainger DC. Genomic analysis of protein-DNA interactions in bacteria: insights into transcription and chromosome organization. Molecular Microbiology. 65: 21-6. PMID 17581117 DOI: 10.1111/j.1365-2958.2007.05781.x  1
2007 Birney E, Stamatoyannopoulos JA, Dutta A, Guigó R, Gingeras TR, Margulies EH, Weng Z, Snyder M, Dermitzakis ET, Thurman RE, Kuehn MS, Taylor CM, Neph S, Koch CM, ... ... Struhl K, et al. Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature. 447: 799-816. PMID 17571346 DOI: 10.1038/nature05874  0.48
2007 Struhl K. Transcriptional noise and the fidelity of initiation by RNA polymerase II. Nature Structural & Molecular Biology. 14: 103-5. PMID 17277804 DOI: 10.1038/nsmb0207-103  1
2006 Yang A, Zhu Z, Kapranov P, McKeon F, Church GM, Gingeras TR, Struhl K. Relationships between p63 binding, DNA sequence, transcription activity, and biological function in human cells. Molecular Cell. 24: 593-602. PMID 17188034 DOI: 10.1016/j.molcel.2006.10.018  0.32
2006 Ghosh S, Hirsch HA, Sekinger E, Struhl K, Gingeras TR. Rank-statistics based enrichment-site prediction algorithm developed for chromatin immunoprecipitation on chip experiments. Bmc Bioinformatics. 7: 434. PMID 17022824 DOI: 10.1186/1471-2105-7-434  1
2006 Wade JT, Castro Roa D, Grainger DC, Hurd D, Busby SJ, Struhl K, Nudler E. Extensive functional overlap between sigma factors in Escherichia coli. Nature Structural & Molecular Biology. 13: 806-14. PMID 16892065 DOI: 10.1038/nsmb1130  1
2006 Pascual-Ahuir A, Struhl K, Proft M. Genome-wide location analysis of the stress-activated MAP kinase Hog1 in yeast. Methods (San Diego, Calif.). 40: 272-8. PMID 16884916 DOI: 10.1016/j.ymeth.2006.06.007  1
2006 Miotto B, Struhl K. Differential gene regulation by selective association of transcriptional coactivators and bZIP DNA-binding domains. Molecular and Cellular Biology. 26: 5969-82. PMID 16880509 DOI: 10.1128/MCB.00696-06  1
2006 Proft M, Mas G, de Nadal E, Vendrell A, Noriega N, Struhl K, Posas F. The stress-activated Hog1 kinase is a selective transcriptional elongation factor for genes responding to osmotic stress. Molecular Cell. 23: 241-50. PMID 16857590 DOI: 10.1016/j.molcel.2006.05.031  1
2006 Schwabish MA, Struhl K. Asf1 mediates histone eviction and deposition during elongation by RNA polymerase II. Molecular Cell. 22: 415-22. PMID 16678113 DOI: 10.1016/j.molcel.2006.03.014  1
2006 Hall DB, Wade JT, Struhl K. An HMG protein, Hmo1, associates with promoters of many ribosomal protein genes and throughout the rRNA gene locus in Saccharomyces cerevisiae. Molecular and Cellular Biology. 26: 3672-9. PMID 16612005 DOI: 10.1128/MCB.26.9.3672-3679.2006  1
2006 Fan X, Chou DM, Struhl K. Activator-specific recruitment of Mediator in vivo. Nature Structural & Molecular Biology. 13: 117-20. PMID 16429153 DOI: 10.1038/nsmb1049  1
2005 Geisberg JV, Struhl K. Analysis of protein co-occupancy by quantitative sequential chromatin immunoprecipitation. Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. Unit 21.8. PMID 18265359 DOI: 10.1002/0471142727.mb2108s70  1
2005 Aparicio O, Geisberg JV, Sekinger E, Yang A, Moqtaderi Z, Struhl K. Chromatin immunoprecipitation for determining the association of proteins with specific genomic sequences in vivo. Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. Unit 21.3. PMID 18265358 DOI: 10.1002/0471142727.mb2103s69  1
2005 Joshi AA, Struhl K. Eaf3 chromodomain interaction with methylated H3-K36 links histone deacetylation to Pol II elongation. Molecular Cell. 20: 971-8. PMID 16364921 DOI: 10.1016/j.molcel.2005.11.021  1
2005 Gibbons FD, Proft M, Struhl K, Roth FP. Chipper: discovering transcription-factor targets from chromatin immunoprecipitation microarrays using variance stabilization. Genome Biology. 6: R96. PMID 16277751 DOI: 10.1186/gb-2005-6-11-r96  1
2005 Proft M, Gibbons FD, Copeland M, Roth FP, Struhl K. Genomewide identification of Sko1 target promoters reveals a regulatory network that operates in response to osmotic stress in Saccharomyces cerevisiae. Eukaryotic Cell. 4: 1343-52. PMID 16087739 DOI: 10.1128/EC.4.8.1343-1352.2005  1
2005 Sekinger EA, Moqtaderi Z, Struhl K. Intrinsic histone-DNA interactions and low nucleosome density are important for preferential accessibility of promoter regions in yeast. Molecular Cell. 18: 735-48. PMID 15949447 DOI: 10.1016/j.molcel.2005.05.003  1
2005 Katan-Khaykovich Y, Struhl K. Heterochromatin formation involves changes in histone modifications over multiple cell generations. The Embo Journal. 24: 2138-49. PMID 15920479 DOI: 10.1038/sj.emboj.7600692  1
2005 Mason PB, Struhl K. Distinction and relationship between elongation rate and processivity of RNA polymerase II in vivo. Molecular Cell. 17: 831-40. PMID 15780939 DOI: 10.1016/j.molcel.2005.02.017  1
2005 Struhl K. Transcriptional activation: mediator can act after preinitiation complex formation. Molecular Cell. 17: 752-4. PMID 15780930 DOI: 10.1016/j.molcel.2005.03.002  1
2004 Moqtaderi Z, Struhl K. Defining in vivo targets of nuclear proteins by chromatin immunoprecipitation and microarray analysis. Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. Unit 21.9. PMID 18265347 DOI: 10.1002/0471142727.mb2109s68  1
2004 Aparicio O, Geisberg JV, Struhl K. Chromatin immunoprecipitation for determining the association of proteins with specific genomic sequences in vivo. Current Protocols in Cell Biology / Editorial Board, Juan S. Bonifacino ... [Et Al.]. Unit 17.7. PMID 18228445 DOI: 10.1002/0471143030.cb1707s23  1
2004 Wade JT, Struhl K. Association of RNA polymerase with transcribed regions in Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 101: 17777-82. PMID 15596728 DOI: 10.1073/pnas.0404305101  1
2004 Schwabish MA, Struhl K. Evidence for eviction and rapid deposition of histones upon transcriptional elongation by RNA polymerase II. Molecular and Cellular Biology. 24: 10111-7. PMID 15542822 DOI: 10.1128/MCB.24.23.10111-10117.2004  1
2004 Geisberg JV, Struhl K. Quantitative sequential chromatin immunoprecipitation, a method for analyzing co-occupancy of proteins at genomic regions in vivo. Nucleic Acids Research. 32: e151. PMID 15520460 DOI: 10.1093/nar/gnh148  1
2004 Feingold EA, Good PJ, Guyer MS, Kamholz S, Liefer L, Wetterstrand K, Collins FS, Gingeras TR, Kampa D, Sekinger EA, Cheng J, Hirsch H, Ghosh S, Zhu Z, Patel S, ... ... Struhl K, et al. The ENCODE (ENCyclopedia of DNA Elements) Project Science. 306: 636-640. PMID 15499007 DOI: 10.1126/science.1105136  1
2004 Grainger DC, Overton TW, Reppas N, Wade JT, Tamai E, Hobman JL, Constantinidou C, Struhl K, Church G, Busby SJW. Genomic studies with Escherichia coli MelR protein: Applications of chromatin immunoprecipitation and microarrays Journal of Bacteriology. 186: 6938-6943. PMID 15466047 DOI: 10.1128/JB.186.20.6938-6943.2004  1
2004 Proft M, Struhl K. MAP kinase-mediated stress relief that precedes and regulates the timing of transcriptional induction Cell. 118: 351-361. PMID 15294160 DOI: 10.1016/j.cell.2004.07.016  1
2004 Bourbon HM, Aguilera A, Ansari AZ, Asturias FJ, Berk AJ, Bjorklund S, Blackwell TK, Borggrefe T, Carey M, Carlson M, Conaway JW, Conaway RC, Emmons SW, Fondell JD, Freedman LP, ... ... Struhl K, et al. A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II. Molecular Cell. 14: 553-7. PMID 15175151 DOI: 10.1016/j.molcel.2004.05.011  1
2004 Geisberg JV, Struhl K. Cellular stress alters the transcriptional properties of promoter-bound Mot1-TBP complexes Molecular Cell. 14: 479-489. PMID 15149597 DOI: 10.1016/j.molcel.2004.05.003  1
2004 Moqtaderi Z, Struhl K. Genome-wide occupancy profile of the RNA polymerase III machinery in Saccharomyces cerevisiae reveals loci with incomplete transcription complexes Molecular and Cellular Biology. 24: 4118-4127. PMID 15121834 DOI: 10.1128/MCB.24.10.4118-4127.2004  1
2004 Cawley S, Bekiranov S, Ng HH, Kapranov P, Sekinger EA, Kampa D, Piccolboni A, Sementchenko V, Cheng J, Williams AJ, Wheeler R, Wong B, Drenkow J, Yamanaka M, Patel S, ... ... Struhl K, et al. Unbiased Mapping of Transcription Factor Binding Sites along Human Chromosomes 21 and 22 Points to Widespread Regulation of Noncoding RNAs Cell. 116: 499-509. PMID 14980218 DOI: 10.1016/S0092-8674(04)00127-8  1
2004 Reid JL, Moqtaderi Z, Struhl K. Eaf3 Regulates the Global Pattern of Histone Acetylation in Saccharomyces cerevisiae Molecular and Cellular Biology. 24: 757-764. PMID 14701747 DOI: 10.1128/MCB.24.2.757-764.2004  1
2003 Mason PB, Struhl K. The FACT Complex Travels with Elongating RNA Polymerase II and is Important for the Fidelity of Transcriptional Initiation In Vivo Molecular and Cellular Biology. 23: 8323-8333. PMID 14585989 DOI: 10.1128/MCB.23.22.8323-8333.2003  1
2003 Ng HH, Dole S, Struhl K. The Rtf1 component of the Paf1 transcriptional elongation complex is required for ubiquitination of histone H2B. The Journal of Biological Chemistry. 278: 33625-8. PMID 12876293 DOI: 10.1074/jbc.C300270200  1
2003 Ng HH, Robert F, Young RA, Struhl K. Targeted recruitment of Set1 histone methylase by elongating Pol II provides a localized mark and memory of recent transcriptional activity. Molecular Cell. 11: 709-19. PMID 12667453 DOI: 10.1016/S1097-2765(03)00092-3  1
2003 Ng HH, Ciccone DN, Morshead KB, Oettinger MA, Struhl K. Lysine-79 of histone H3 is hypomethylated at silenced loci in yeast and mammalian cells: a potential mechanism for position-effect variegation. Proceedings of the National Academy of Sciences of the United States of America. 100: 1820-5. PMID 12574507 DOI: 10.1073/pnas.0437846100  1
2002 Geisberg JV, Moqtaderi Z, Kuras L, Struhl K. Mot1 associates with transcriptionally active promoters and inhibits association of NC2 in Saccharomyces cerevisiae. Molecular and Cellular Biology. 22: 8122-34. PMID 12417716 DOI: 10.1128/MCB.22.23.8122-8134.2002  1
2002 Hall DB, Struhl K. The VP16 activation domain interacts with multiple transcriptional components as determined by protein-protein cross-linking in vivo. The Journal of Biological Chemistry. 277: 46043-50. PMID 12297514 DOI: 10.1074/jbc.M208911200  1
2002 Deckert J, Struhl K. Targeted recruitment of Rpd3 histone deacetylase represses transcription by inhibiting recruitment of Swi/Snf, SAGA, and TATA binding protein. Molecular and Cellular Biology. 22: 6458-70. PMID 12192044 DOI: 10.1128/MCB.22.18.6458-6470.2002  1
2002 Ng HH, Xu RM, Zhang Y, Struhl K. Ubiquitination of histone H2B by Rad6 is required for efficient Dot1-mediated methylation of histone H3 lysine 79. The Journal of Biological Chemistry. 277: 34655-7. PMID 12167634 DOI: 10.1074/jbc.C200433200  1
2002 Feng Q, Wang H, Ng HH, Erdjument-Bromage H, Tempst P, Struhl K, Zhang Y. Methylation of H3-lysine 79 is mediated by a new family of HMTases without a SET domain. Current Biology : Cb. 12: 1052-8. PMID 12123582 DOI: 10.1016/S0960-9822(02)00901-6  1
2002 Proft M, Struhl K. Hog1 kinase converts the Sko1-Cyc8-Tup1 repressor complex into an activator that recruits SAGA and SWI/SNF in response to osmotic stress. Molecular Cell. 9: 1307-17. PMID 12086627 DOI: 10.1016/S1097-2765(02)00557-9  1
2002 Ng HH, Feng Q, Wang H, Erdjument-Bromage H, Tempst P, Zhang Y, Struhl K. Lysine methylation within the globular domain of histone H3 by Dot1 is important for telomeric silencing and Sir protein association. Genes & Development. 16: 1518-27. PMID 12080090 DOI: 10.1101/gad.1001502  1
2002 Mencía M, Moqtaderi Z, Geisberg JV, Kuras L, Struhl K. Activator-specific recruitment of TFIID and regulation of ribosomal protein genes in yeast. Molecular Cell. 9: 823-33. PMID 11983173 DOI: 10.1016/S1097-2765(02)00490-2  1
2002 Strässer K, Masuda S, Mason P, Pfannstiel J, Oppizzi M, Rodriguez-Navarro S, Rondón AG, Aguilera A, Struhl K, Reed R, Hurt E. TREX is a conserved complex coupling transcription with messenger RNA export. Nature. 417: 304-8. PMID 11979277 DOI: 10.1038/nature746  1
2002 Ng HH, Robert F, Young RA, Struhl K. Genome-wide location and regulated recruitment of the RSC nucleosome-remodeling complex. Genes & Development. 16: 806-19. PMID 11937489 DOI: 10.1101/gad.978902  1
2002 Katan-Khaykovich Y, Struhl K. Dynamics of global histone acetylation and deacetylation in vivo: rapid restoration of normal histone acetylation status upon removal of activators and repressors. Genes & Development. 16: 743-52. PMID 11914279 DOI: 10.1101/gad.967302  1
2001 Struhl K. Reagents and radioisotopes used to manipulate nucleic acids. Current Protocols in Immunology / Edited by John E. Coligan ... [Et Al.]. Unit 10.9. PMID 18432701 DOI: 10.1002/0471142735.im1009s02  1
2001 Brown T, Struhl K. Hybridization analysis of DNA blots. Current Protocols in Protein Science / Editorial Board, John E. Coligan ... [Et Al.]. Appendix 4H. PMID 18429083 DOI: 10.1002/0471140864.psa04hs13  1
2001 Seidman CE, Struhl K. Introduction of plasmid DNA into cells. Current Protocols in Protein Science / Editorial Board, John E. Coligan ... [Et Al.]. 4D. PMID 18429079 DOI: 10.1002/0471140864.psa04ds13  1
2001 Seidman CE, Struhl K. Introduction of plasmid DNA into cells. Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. Appendix 1L. PMID 18428443 DOI: 10.1002/0471142301.nsa01ls11  1
2001 Tabor S, Struhl K. Enzymatic labeling of DNA. Current Protocols in Human Genetics / Editorial Board, Jonathan L. Haines ... [Et Al.]. Appendix 3E. PMID 18428222 DOI: 10.1002/0471142905.hga03es00  1
2001 Greene JM, Struhl K. S1 analysis of messenger RNA using single-stranded DNA probes. Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. Unit4.6. PMID 18265240 DOI: 10.1002/0471142727.mb0406s45  1
2001 Tabor S, Struhl K, Scharf SJ, Gelfand DH. DNA-dependent DNA polymerases. Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. Unit3.5. PMID 18265231 DOI: 10.1002/0471142727.mb0305s37  1
2001 Struhl K. Reagents and radioisotopes used to manipulate nucleic acids. Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. Unit3.4. PMID 18265230 DOI: 10.1002/0471142727.mb0304s09  1
2001 Struhl K. Subcloning of DNA fragments. Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. Unit3.16. PMID 18265225 DOI: 10.1002/0471142727.mb0316s13  1
2001 Struhl K. Ribonucleases. Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. Unit3.13. PMID 18265222 DOI: 10.1002/0471142727.mb0313s08  1
2001 Tabor S, Struhl K. Endonucleases. Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. Unit3.12. PMID 18265221 DOI: 10.1002/0471142727.mb0312s08  1
2001 Struhl K. Analysis of DNA-protein interactions using proteins synthesized in vitro from cloned genes. Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. Unit 12.9. PMID 18265092 DOI: 10.1002/0471142727.mb1209s24  1
2001 Baldwin AS, Oettinger M, Struhl K. Methylation and uracil interference assays for analysis of protein-DNA interactions. Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. Unit 12.3. PMID 18265086 DOI: 10.1002/0471142727.mb1203s36  1
2001 Struhl K. Synthesizing proteins in vitro by transcription and translation of cloned genes. Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. Unit 10.17. PMID 18265057 DOI: 10.1002/0471142727.mb1017s48  1
2001 Seidman CE, Struhl K, Sheen J, Jessen T. Introduction of plasmid DNA into cells. Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. Unit1.8. PMID 18265047 DOI: 10.1002/0471142727.mb0108s37  1
2001 Struhl K. A paradigm for precision Science. 293: 1054-1055. PMID 11498564 DOI: 10.1126/science.1064050  1
2001 Kulish D, Struhl K. TFIIS enhances transcriptional elongation through an artificial arrest site in vivo Molecular and Cellular Biology. 21: 4162-4168. PMID 11390645 DOI: 10.1128/MCB.21.13.4162-4168.2001  1
2001 Lee M, Struhl K. Multiple functions of the nonconserved N-terminal domain of yeast TATA-binding protein Genetics. 158: 87-93. PMID 11333220  1
2001 Geisberg JV, Holstege FC, Young RA, Struhl K. Yeast NC2 associates with the RNA polymerase II preinitiation complex and selectively affects transcription in vivo. Molecular and Cellular Biology. 21: 2736-42. PMID 11283253 DOI: 10.1128/MCB.21.8.2736-2742.2001  1
2001 Deckert J, Struhl K. Histone acetylation at promoters is differentially affected by specific activators and repressors Molecular and Cellular Biology. 21: 2726-2735. PMID 11283252 DOI: 10.1128/MCB.21.8.2726-2735.2001  1
2001 Mencía M, Struhl K. Region of yeast TAF 130 required for TFIID to associate with promoters Molecular and Cellular Biology. 21: 1145-1154. PMID 11158301 DOI: 10.1128/MCB.21.4.1145-1154.2001  1
2000 Kuo MH, Vom Baur E, Struhl K, Allis CD. Gcn4 activator targets Gcn5 histone acetyltransferase to specific promoters independently of transcription Molecular Cell. 6: 1309-1320. PMID 11163205 DOI: 10.1016/S1097-2765(00)00129-5  1
2000 Reid JL, Iyer VR, Brown PO, Struhl K. Coordinate regulation of yeast ribosomal protein genes is associated with targeted recruitment of Esa1 histone acetylase. Molecular Cell. 6: 1297-307. PMID 11163204 DOI: 10.1016/S1097-2765(00)00128-3  1
2000 Mai X, Chou S, Struhl K. Preferential accessibility of the yeast his3 promoter is determined by a general property of the DNA sequence, not by specific elements Molecular and Cellular Biology. 20: 6668-6676. PMID 10958664 DOI: 10.1128/MCB.20.18.6668-6676.2000  1
2000 Lee M, Chatterjee S, Struhl K. Genetic analysis of the role of POL II holoenzyme components in repression by the Cyc8-Tup1 corepressor in yeast Genetics. 155: 1535-1542. PMID 10924455  1
2000 Dorris DR, Struhl K. Artificial recruitment of TFIID, but not RNA polymerase II holoenzyme, activates transcription in mammalian cells Molecular and Cellular Biology. 20: 4350-4358. PMID 10825198 DOI: 10.1128/MCB.20.12.4350-4358.2000  1
2000 Garcia-Gimeno MA, Struhl K. Aca1 and Aca2, ATF/CREB activators in Saccharomyces cerevisiae, are important for carbon source utilization but not the response to stress Molecular and Cellular Biology. 20: 4340-4349. PMID 10825197 DOI: 10.1128/MCB.20.12.4340-4349.2000  1
2000 Kuras L, Kosa P, Mencia M, Struhl K. TAF-containing and TAF-independent forms of transcriptionally active TBP in vivo Science. 288: 1244-1248. PMID 10818000 DOI: 10.1126/science.288.5469.1244  1
2000 Stargell LA, Moqtaderi Z, Dorris DR, Ogg RC, Struhl K. TFIIA has activator-dependent and core promoter functions in vivo Journal of Biological Chemistry. 275: 12374-12380. PMID 10777519 DOI: 10.1074/jbc.275.17.12374  1
2000 Geisberg JV, Struhl K. TATA-binding protein mutants that increase transcription from enhancerless and repressed promoters in vivo Molecular and Cellular Biology. 20: 1478-1488. PMID 10669725 DOI: 10.1128/MCB.20.5.1478-1488.2000  1
1999 Chou S, Chatterjee S, Lee M, Struhl K. Transcriptional activation in yeast cells lacking transcription factor IIA Genetics. 153: 1573-1581. PMID 10581267  1
1999 Struhl K. Fundamentally different logic of gene regulation in eukaryotes and prokaryotes Cell. 98: 1-4. PMID 10412974 DOI: 10.1016/S0092-8674(00)80599-1  1
1999 Kuras L, Struhl K. Binding of TBP to promoters in vivo is stimulated by activators and requires Pol II holoenzyme Nature. 399: 609-613. PMID 10376605 DOI: 10.1038/21239  1
1999 Keaveney M, Struhl K. Incorporation of Drosophila TAF110 into the yeast TFIID complex does not permit the Sp1 glutamine-rich activation domain to function in vivo Genes to Cells. 4: 197-203. PMID 10336691 DOI: 10.1046/j.1365-2443.1999.00255.x  1
1999 Ranallo RT, Struhl K, Stargell LA. A TATA-binding protein mutant defective for TFIID complex formation in vivo Molecular and Cellular Biology. 19: 3951-3957. PMID 10330135  1
1999 Gaudreau L, Keaveney M, Nevado J, Zaman Z, Bryant GO, Struhl K, Ptashne M. Transcriptional activation by artificial recruitment in yeast is influenced by promoter architecture and downstream sequences. Proceedings of the National Academy of Sciences of the United States of America. 96: 2668-73. PMID 10077568 DOI: 10.1073/pnas.96.6.2668  1
1999 Dreyfuss G, Struhl K. Multiprotein complexes, mechanistic connections and nuclear organization Current Opinion in Cell Biology. 11: 303-306. DOI: 10.1016/S0955-0674(99)80040-4  1
1998 Struhl K, Kadosh D, Keaveney M, Kuras L, Moqtaderi Z. Activation and repression mechanisms in yeast Cold Spring Harbor Symposia On Quantitative Biology. 63: 413-420. PMID 10384306  1
1998 Moqtaderi Z, Keaveney M, Struhl K. The histone H3-like TAF is broadly required for transcription in yeast Molecular Cell. 2: 675-682. PMID 9844639  1
1998 Benson JD, Benson M, Howley PM, Struhl K. Association of distinct yeast Not2 functional domains with components of Gcn5 histone acetylase and Ccr4 transcriptional regulatory complexes Embo Journal. 17: 6714-6722. PMID 9822614  1
1998 Van Heeckeren WJ, Dorris DR, Struhl K. The mating-type proteins of fission yeast induce meiosis by directly activating mei3 transcription Molecular and Cellular Biology. 18: 7317-7326. PMID 9819418  1
1998 Kadosh D, Struhl K. Targeted recruitment of the Sin3-Rpd3 histone deacetylase complex generates a highly localized domain of repressed chromatin in vivo Molecular and Cellular Biology. 18: 5121-5127. PMID 9710596  1
1998 Struhl K, Moqtaderi Z. The TAFS in the HAT Cell. 94: 1-4. PMID 9674419 DOI: 10.1016/S0092-8674(00)81213-1  1
1998 Keaveney M, Struhl K. Activator-mediated recruitment of the RNA polymerase II machinery is the predominant mechanism for transcriptional activation in yeast Molecular Cell. 1: 917-924. PMID 9660975  1
1998 Kadosh D, Struhl K. Histone deacetylase activity of Rpd3 is important for transcriptional repression in vivo Genes and Development. 12: 797-805. PMID 9512514  1
1998 Struhl K. Histone acetylation and transcriptional regulatory mechanisms Genes and Development. 12: 599-606. PMID 9499396  1
1997 Struhl K. Selective roles for TATA-binding-protein-associated factors in vivo Genes and Function. 1: 5-9. PMID 9680324  1
1997 Fernandes L, Rodrigues-Pousada C, Struhl K. Yap, a novel family of eight bZIP proteins in Saccharomyces cerevisiae with distinct biological functions Molecular and Cellular Biology. 17: 6982-6993. PMID 9372930  1
1997 Chou S, Struhl K. Transcriptional activation by TFIIB mutants that are severely impaired in interaction with promoter DNA and acidic activation domains Molecular and Cellular Biology. 17: 6794-6802. PMID 9372910  1
1997 Mahadevan S, Raghunand TR, Panicker S, Struhl K. Characterisation of 3' end formation of the yeast HIS3 mRNA. Gene. 190: 69-76. PMID 9185851 DOI: 10.1016/S0378-1119(96)00708-1  1
1997 Lee M, Struhl K. A severely defective TATA-binding protein-TFIIB interaction does not preclude transcriptional activation in vivo Molecular and Cellular Biology. 17: 1336-1345. PMID 9032260  1
1997 Fernandes L, Struhl K, Rodrigues-Pousada C. Yap, a novel bZlP family of proteins in Saccharomyces cerevisiae Faseb Journal. 11: A1205.  1
1996 Struhl K. Transcriptional enhancement by acidic activators Biochimica Et Biophysica Acta - Reviews On Cancer. 1288: O15-O17. PMID 9011181 DOI: 10.1016/S0304-419X(96)00029-7  1
1996 Moqtaderi Z, Yale JD, Struhl K, Buratowski S. Yeast homologues of higher eukaryotic TFIID subunits. Proceedings of the National Academy of Sciences of the United States of America. 93: 14654-8. PMID 8962109 DOI: 10.1073/pnas.93.25.14654  1
1996 De Rubertis F, Kadosh D, Henchoz S, Pauli D, Reuter G, Struhl K, Spierer P. The histone deacetylase RPD3 counteracts genomic silencing in Drosophila and yeast. Nature. 384: 589-91. PMID 8955276 DOI: 10.1038/384589a0  1
1996 Stargell LA, Struhl K. Mechanisms of transcriptional activation in vivo: Two steps forward Trends in Genetics. 12: 311-315. PMID 8783941 DOI: 10.1016/0168-9525(96)10028-7  1
1996 Moqtaderi Z, Bai Y, Poon D, Well PA, Struhl K. TBP-associated factors are not generally required for transcriptional activation in yeast Nature. 383: 188-191. PMID 8774887 DOI: 10.1038/383188a0  1
1996 Stargell LA, Struhl K. A new class of activation-defective TATA-binding protein mutants: Evidence for two steps of transcriptional activation in vivo Molecular and Cellular Biology. 16: 4456-4464. PMID 8754846  1
1996 Iyer V, Struhl K. Absolute mRNA levels and transcriptional initiation rates in Saccharomyces cerevisiae Proceedings of the National Academy of Sciences of the United States of America. 93: 5208-5212. PMID 8643554 DOI: 10.1073/pnas.93.11.5208  1
1996 Struhl K. Chromatin structure and RNA polymerase II connection: Implications for transcription Cell. 84: 179-182. PMID 8565061 DOI: 10.1016/S0092-8674(00)80970-8  1
1995 Struhl K. Yeast transcriptional regulatory mechanisms Annual Review of Genetics. 29: 651-674. PMID 8825489  1
1995 Iyer V, Struhl K. Mechanism of differential utilization of the his3 TR and TC TATA elements Molecular and Cellular Biology. 15: 7059-7066. PMID 8524273  1
1995 Ponticelli AS, Pardee TS, Struhl K. The glutamine-rich activation domains of human Sp1 do not stimulate transcription in Saccharomyces cerevisiae Molecular and Cellular Biology. 15: 983-988. PMID 7823962  1
1995 Iyer V, Struhl K. Poly(dA:dT), a ubiquitous promoter element that stimulates transcription via its intrinsic DNA structure Embo Journal. 14: 2570-2579. PMID 7781610  1
1995 Chatterjee S, Struhl K. Connecting a promoter-bound protein to TBP bypasses the need for a transcriptional activation domain Nature. 374: 820-822. PMID 7723828  1
1995 Tzamarias D, Struhl K. Distinct TPR motifs of Cyc8 are involved in recruiting the Cyc8-Tup1 corepressor complex to differentially regulated promoters Genes and Development. 9: 821-831. PMID 7705659  1
1995 Stargell LA, Struhl K. The TBP-TFIIA interaction in the response to acidic activators in vivo Science. 269: 75-78. PMID 7604282  1
1995 Lee M, Struhl K. Mutations on the DNA-binding surface of TATA-binding protein can specifically impair the response to acidic activators in vivo Molecular and Cellular Biology. 15: 5461-5469. PMID 7565697  1
1994 Arndt KM, Wobbe CR, Ricupero-Hovasse S, Struhl K, Winston F. Equivalent mutations in the two repeats of yeast TATA-binding protein confer distinct TATA recognition specificities Molecular and Cellular Biology. 14: 3719-3728. PMID 8196615  1
1994 Engelberg D, Klein C, Martinetto H, Struhl K, Karin M. The UV response involving the ras signaling pathway and AP-1 transcription factors is conserved between yeast and mammals Cell. 77: 381-390. PMID 8181058 DOI: 10.1016/0092-8674(94)90153-8  1
1994 Klein C, Struhl K. Protein kinase A mediates growth-regulated expression of yeast ribosomal protein genes by modulating RAP1 transcriptional activity Molecular and Cellular Biology. 14: 1920-1928. PMID 8114723  1
1994 Struhl K. Duality of TBP, the universal transcription factor Science. 263: 1103-1104. PMID 8108728  1
1994 Tzamarias D, Struhl K. Functional dissection of the yeast Cyc8-Tup1 transcriptional co-repressor complex Nature. 369: 758-761. PMID 8008070 DOI: 10.1038/369758a0  1
1994 Klein C, Struhl K. Increased recruitment of TATA-binding protein to the promoter by transcriptional activation domains in vivo Science. 266: 280-282. PMID 7939664  1
1994 Collart MA, Struhl K. NOT1(CDC39), NOT2(CDC36), NOT3, and NOT4 encode a global-negative regulator of transcription that differentially affects TATA-element utilization Genes and Development. 8: 525-537. PMID 7926748  1
1994 Cormack BP, Strubin M, Stargell LA, Struhl K. Conserved and nonconserved functions of the yeast and human TATA-binding proteins Genes and Development. 8: 1335-1343. PMID 7926734  1
1993 Kim J, Tzamarias D, Ellenberger T, Harrison SC, Struhl K. Adaptability at the protein-DNA interface is an important aspect of sequence recognition by bZIP proteins Proceedings of the National Academy of Sciences of the United States of America. 90: 4513-4517. PMID 8506292  1
1993 Collart MA, Struhl K. CDC39, an essential nuclear protein that negatively regulates transcription and differentially affects the constitutive and inducible HIS3 promoters Embo Journal. 12: 177-186. PMID 8428577  1
1993 Pu WT, Struhl K. Dimerization of leucine zippers analyzed by random selection Nucleic Acids Research. 21: 4348-4355. PMID 8414991 DOI: 10.1093/nar/21.18.4348  1
1993 Struhl K. Yeast transcription factors Current Opinion in Cell Biology. 5: 513-520. PMID 8352970 DOI: 10.1016/0955-0674(93)90018-L  1
1993 Cormack BP, Struhl K. Regional codon randomization: Defining a TATA-binding protein surface required for RNA polymerase III transcription Science. 262: 244-248. PMID 8211143  1
1993 Struhl K. Chromatin and transcription factors : who's on first? Current Biology. 3: 220-222. DOI: 10.1016/0960-9822(93)90338-O  1
1993 Collart MA, Struhl K. Addendum: CDC39, an essential nuclear protein that negatively regulates transcription and differently affects the constitutive and inducible HIS3 promoters (The EMBO journal (1993)12(177-186)) Embo Journal. 12: 2990.  1
1992 Cormack BP, Struhl K. The TATA-binding protein is required for transcription by all three nuclear RNA polymerases in yeast cells Cell. 69: 685-696. PMID 1586947 DOI: 10.1016/0092-8674(92)90232-2  1
1992 Struhl K, Cameron JR, Davis RW. Functional genetic expression of eukaryotic DNA in Escherichia coli. 1976. Biotechnology (Reading, Mass.). 24: 353-7. PMID 1422039  0.96
1991 Cormack BP, Strubin M, Ponticelli AS, Struhl K. Functional differences between yeast and human TFIID are localized to the highly conserved region Cell. 65: 341-348. PMID 2015628 DOI: 10.1016/0092-8674(91)90167-W  1
1981 Struhl K, Davis RW. Position effects in Saccharomyces cerevisiae. Journal of Molecular Biology. 152: 569-75. PMID 7035683  0.96
1981 Struhl K, Davis RW. Promotor mutants of the yeast his3 gene. Journal of Molecular Biology. 152: 553-68. PMID 6173490  0.96
1981 Struhl K, Davis RW. Transcription of the his3 gene region in Saccharomyces cerevisiae. Journal of Molecular Biology. 152: 535-52. PMID 6173489  0.96
1980 Struhl K, Davis RW. Conservation and DNA sequence arrangement of the DNA polymerase I gene region from Klebsiella aerogenes, Klebsiella pneumoniae and Escherichia coli. Journal of Molecular Biology. 141: 343-68. PMID 6449602  0.96
1980 Struhl K, Stinchcomb DT, Davis RW. A physiological study of functional expression in Escherichia coli of the cloned yeast imidazoleglycerolphosphate dehydratase gene. Journal of Molecular Biology. 136: 291-307. PMID 6445419 DOI: 10.1016/0022-2836(80)90375-7  1
1980 Struhl K, Davis RW. A physical, genetic and transcriptional map of the cloned his3 gene region of Saccharomyces cerevisiae. Journal of Molecular Biology. 136: 309-32. PMID 6246242  0.96
1979 Botstein D, Falco SC, Stewart SE, Brennan M, Scherer S, Stinchcomb DT, Struhl K, Davis RW. Sterile host yeasts (SHY): a eukaryotic system of biological containment for recombinant DNA experiments. Gene. 8: 17-24. PMID 395030 DOI: 10.1016/0378-1119(79)90004-0  1
1979 Stinchcomb DT, Struhl K, Davis RW. Isolation and characterisation of a yeast chromosomal replicator. Nature. 282: 39-43. PMID 388229 DOI: 10.1038/282039a0  1
1979 Struhl K, Davis RW, Fink GR. Suppression of a yeast amber mutation in Escherichia coli. Nature. 279: 78-9. PMID 377096  0.96
1979 Struhl K, Stinchcomb DT, Scherer S, Davis RW. High-frequency transformation of yeast: autonomous replication of hybrid DNA molecules. Proceedings of the National Academy of Sciences of the United States of America. 76: 1035-9. PMID 375221  1
1977 Struhl K, Davis RW. Production of a functional eukaryotic enzyme in Escherichia coli: cloning and expression of the yeast structural gene for imidazole-glycerolphosphate dehydratase (his3). Proceedings of the National Academy of Sciences of the United States of America. 74: 5255-9. PMID 341150  0.96
1976 Struhl K, Magasanik B. Ammonia-sensitive mutant of Klebsiella aerogenes. Journal of Bacteriology. 126: 739-42. PMID 1262316  1
1976 Struhl K, Cameron JR, Davis RW. Functional genetic expression of eukaryotic DNA in Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 73: 1471-5. PMID 775490  0.96
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