| Year |
Citation |
Score |
| 2022 |
Featherstone RE, Shimada T, Crown LM, Melnychenko O, Yi J, Matsumoto M, Tajinda K, Mihara T, Adachi M, Siegel SJ. Calcium/calmodulin-dependent protein kinase IIα heterozygous knockout mice show electroencephalogram and behavioral changes characteristic of a subpopulation of schizophrenia and intellectual impairment. Neuroscience. 499: 104-117. PMID 35901933 DOI: 10.1016/j.neuroscience.2022.07.023 |
0.402 |
|
| 2020 |
Javitt DC, Siegel SJ, Spencer KM, Mathalon DH, Hong LE, Martinez A, Ehlers CL, Abbas AI, Teichert T, Lakatos P, Womelsdorf T. A roadmap for development of neuro-oscillations as translational biomarkers for treatment development in neuropsychopharmacology. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 32375159 DOI: 10.1038/S41386-020-0697-9 |
0.305 |
|
| 2020 |
Chen A, McCarron M, Schooner L, Brasfield K, Chesley J, Tung A, Wilson M, Lee D, Siegel S. Transcranial Magnetic Stimulation for Schizophrenia Biological Psychiatry. 87. DOI: 10.1016/J.Biopsych.2020.02.613 |
0.326 |
|
| 2019 |
Ferri SL, Pallathra AA, Kim H, Dow HC, Raje P, McMullen M, Bilker WB, Siegel SJ, Abel T, Brodkin ES. Sociability development in mice with cell-specific deletion of the NMDA receptor NR1 subunit gene. Genes, Brain, and Behavior. e12624. PMID 31721416 DOI: 10.1111/Gbb.12624 |
0.394 |
|
| 2019 |
Zhang RV, Featherstone RE, Melynchenko O, Gifford R, Weger R, Liang Y, Siegel SJ. High-beta/low-gamma frequency activity reflects top-down predictive coding during a spatial working memory test. Experimental Brain Research. PMID 31093716 DOI: 10.1007/S00221-019-05558-3 |
0.33 |
|
| 2019 |
Zieba J, Sinclair D, Sebree T, Bonn-Miller M, Gutterman D, Siegel S, Karl T. Cannabidiol (CBD) reduces anxiety-related behavior in mice via an FMRP1-independent mechanism. Pharmacology, Biochemistry, and Behavior. PMID 31063743 DOI: 10.1016/J.Pbb.2019.05.002 |
0.365 |
|
| 2019 |
Ward KR, Featherstone RE, Naschek MJ, Melnychenko O, Banerjee A, Yi J, Gifford RL, Borgmann-Winter KE, Salter MW, Hahn CG, Siegel SJ. Src deficient mice demonstrate behavioral and electrophysiological alterations relevant to psychiatric and developmental disease. Progress in Neuro-Psychopharmacology & Biological Psychiatry. PMID 30826459 DOI: 10.1016/J.Pnpbp.2019.02.017 |
0.469 |
|
| 2018 |
Port RG, Berman J, Liu S, Featherstone RE, Roberts TPL, Siegel SJ. Parvalbumin cell ablation of NMDA-R1 leads to altered phase, but not amplitude, of gamma-band cross frequency coupling. Brain Connectivity. PMID 30588822 DOI: 10.1089/Brain.2018.0639 |
0.356 |
|
| 2018 |
Wang HY, MacDonald ML, Borgmann-Winter KE, Banerjee A, Sleiman P, Tom A, Khan A, Lee KC, Roussos P, Siegel SJ, Hemby SE, Bilker WB, Gur RE, Hahn CG. mGluR5 hypofunction is integral to glutamatergic dysregulation in schizophrenia. Molecular Psychiatry. PMID 30214040 DOI: 10.1038/S41380-018-0234-Y |
0.398 |
|
| 2018 |
Forrest AD, Bang J, Featherstone RE, Bloom JH, Luminais MS, Zhang RV, Gajewski CR, McMullen MF, Liang Y, Siegel SJ. Pyramidal cell-selective GluN1 knockout causes impairments in salience attribution and related EEG activity. Experimental Brain Research. PMID 29350251 DOI: 10.1007/S00221-017-5152-8 |
0.483 |
|
| 2017 |
Grissom NM, McKee SE, Schoch H, Bowman N, Havekes R, O'Brien WT, Mahrt E, Siegel S, Commons K, Portfors C, Nickl-Jockschat T, Reyes TM, Abel T. Male-specific deficits in natural reward learning in a mouse model of neurodevelopmental disorders. Molecular Psychiatry. PMID 29038598 DOI: 10.1038/Mp.2017.184 |
0.305 |
|
| 2017 |
Port RG, Gajewski C, Krizman E, Dow HC, Hirano S, Brodkin ES, Carlson GC, Robinson MB, Roberts TPL, Siegel SJ. Protocadherin 10 alters γ oscillations, amino acid levels, and their coupling; baclofen partially restores these oscillatory deficits. Neurobiology of Disease. PMID 28844789 DOI: 10.1016/J.Nbd.2017.08.013 |
0.403 |
|
| 2017 |
Featherstone RE, Melnychenko O, Siegel SJ. Mismatch negativity in preclinical models of schizophrenia. Schizophrenia Research. PMID 28768598 DOI: 10.1016/J.Schres.2017.07.039 |
0.412 |
|
| 2017 |
Mihara T, Mensah-Brown K, Sobota R, Lin R, Featherstone R, Siegel SJ. Amygdala activity associated with social choice in mice. Behavioural Brain Research. PMID 28438555 DOI: 10.1016/J.Bbr.2017.04.040 |
0.681 |
|
| 2017 |
Siegel S, Sinclair D, Matsumoto M, Featherstone R, Melnechenko O, Nascheck M, Weger R, Akuzawa S, Pance K, Wright S, Nam J, Du A. 116.1 GABA-B Agonist Baclofen Normalizes Auditory-Evoked Neural Oscillations and Some Cognitive Deficits in a Fragile X Syndrome Mouse Model Schizophrenia Bulletin. 43: S62-S62. DOI: 10.1093/Schbul/Sbx021.163 |
0.326 |
|
| 2017 |
Siegel S, Featherstone R, Matsumoto M. 116. MMN as a Sensitive Measure of Subtle Changes in NMDAR-Mediated Glutamate Transmission in Mice Biological Psychiatry. 81: S49. DOI: 10.1016/J.Biopsych.2017.02.128 |
0.357 |
|
| 2016 |
Choi CH, Schoenfeld BP, Bell AJ, Hinchey J, Rosenfelt C, Gertner MJ, Campbell SR, Emerson D, Hinchey P, Kollaros M, Ferrick NJ, Chambers DB, Langer S, Sust S, Malik A, ... ... Siegel SJ, et al. Multiple Drug Treatments That Increase cAMP Signaling Restore Long-Term Memory and Aberrant Signaling in Fragile X Syndrome Models. Frontiers in Behavioral Neuroscience. 10: 136. PMID 27445731 DOI: 10.3389/Fnbeh.2016.00136 |
0.31 |
|
| 2016 |
Sinclair D, Oranje B, Razak KA, Siegel SJ, Schmid S. Sensory processing in autism spectrum disorders and Fragile X syndrome-From the clinic to animal models. Neuroscience and Biobehavioral Reviews. PMID 27235081 DOI: 10.1016/J.Neubiorev.2016.05.029 |
0.354 |
|
| 2015 |
Kogan JH, Gross AK, Featherstone RE, Shin R, Chen Q, Heusner CL, Adachi M, Lin A, Walton NM, Miyoshi S, Miyake S, Tajinda K, Ito H, Siegel SJ, Matsumoto M. Mouse Model of Chromosome 15q13.3 Microdeletion Syndrome Demonstrates Features Related to Autism Spectrum Disorder. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 16282-16294. PMID 26658876 DOI: 10.1523/Jneurosci.3967-14.2015 |
0.388 |
|
| 2015 |
White RS, Siegel SJ. Cellular and circuit models of increased resting-state network gamma activity in schizophrenia. Neuroscience. PMID 26577758 DOI: 10.1016/j.neuroscience.2015.11.011 |
0.417 |
|
| 2015 |
Featherstone RE, Siegel SJ. The Role of Nicotine in Schizophrenia. International Review of Neurobiology. 124: 23-78. PMID 26472525 DOI: 10.1016/Bs.Irn.2015.07.002 |
0.415 |
|
| 2015 |
Dodman K, Featherstone RE, Bang J, Liang Y, Siegel SJ. Ceftriaxone reverses ketamine-induced lasting EEG and astrocyte alterations in juvenile mice. Drug and Alcohol Dependence. 156: 14-20. PMID 26442907 DOI: 10.1016/J.Drugalcdep.2015.07.1198 |
0.357 |
|
| 2015 |
Nagy LR, Featherstone RE, Hahn CG, Siegel SJ. Delayed emergence of behavioral and electrophysiological effects following juvenile ketamine exposure in mice. Translational Psychiatry. 5: e635. PMID 26371763 DOI: 10.1038/Tp.2015.111 |
0.407 |
|
| 2015 |
Sobota R, Mihara T, Forrest A, Featherstone RE, Siegel SJ. Oxytocin reduces amygdala activity, increases social interactions, and reduces anxiety-like behavior irrespective of NMDAR antagonism. Behavioral Neuroscience. 129: 389-98. PMID 26214213 DOI: 10.1037/Bne0000074 |
0.344 |
|
| 2015 |
Featherstone RE, McMullen MF, Ward KR, Bang J, Xiao J, Siegel SJ. EEG biomarkers of target engagement, therapeutic effect, and disease process. Annals of the New York Academy of Sciences. 1344: 12-26. PMID 25823856 DOI: 10.1111/Nyas.12745 |
0.511 |
|
| 2015 |
Choi CH, Schoenfeld BP, Weisz ED, Bell AJ, Chambers DB, Hinchey J, Choi RJ, Hinchey P, Kollaros M, Gertner MJ, Ferrick NJ, Terlizzi AM, Yohn N, Koenigsberg E, Liebelt DA, ... ... Siegel SJ, et al. PDE-4 inhibition rescues aberrant synaptic plasticity in Drosophila and mouse models of fragile X syndrome. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 396-408. PMID 25568131 DOI: 10.1523/Jneurosci.1356-12.2015 |
0.356 |
|
| 2015 |
Tatard-Leitman VM, Jutzeler CR, Suh J, Saunders JA, Billingslea EN, Morita S, White R, Featherstone RE, Ray R, Ortinski PI, Banerjee A, Gandal MJ, Lin R, Alexandrescu A, Liang Y, ... ... Siegel SJ, et al. Pyramidal cell selective ablation of N-methyl-D-aspartate receptor 1 causes increase in cellular and network excitability. Biological Psychiatry. 77: 556-68. PMID 25156700 DOI: 10.1016/J.Biopsych.2014.06.026 |
0.787 |
|
| 2014 |
Port RG, Gandal MJ, Roberts TP, Siegel SJ, Carlson GC. Convergence of circuit dysfunction in ASD: a common bridge between diverse genetic and environmental risk factors and common clinical electrophysiology. Frontiers in Cellular Neuroscience. 8: 414. PMID 25538564 DOI: 10.3389/Fncel.2014.00414 |
0.639 |
|
| 2014 |
Featherstone RE, Shin R, Kogan JH, Liang Y, Matsumoto M, Siegel SJ. Mice with subtle reduction of NMDA NR1 receptor subunit expression have a selective decrease in mismatch negativity: Implications for schizophrenia prodromal population. Neurobiology of Disease. 73: 289-295. PMID 25461194 DOI: 10.1016/J.Nbd.2014.10.010 |
0.505 |
|
| 2014 |
Forrest AD, Coto CA, Siegel SJ. Animal Models of Psychosis: Current State and Future Directions. Current Behavioral Neuroscience Reports. 1: 100-116. PMID 25215267 DOI: 10.1007/s40473-014-0013-2 |
0.306 |
|
| 2014 |
Billingslea EN, Tatard-Leitman VM, Anguiano J, Jutzeler CR, Suh J, Saunders JA, Morita S, Featherstone RE, Ortinski PI, Gandal MJ, Lin R, Liang Y, Gur RE, Carlson GC, Hahn CG, ... Siegel SJ, et al. Parvalbumin cell ablation of NMDA-R1 causes increased resting network excitability with associated social and self-care deficits. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 1603-13. PMID 24525709 DOI: 10.1038/Npp.2014.7 |
0.825 |
|
| 2014 |
Featherstone RE, Nagy LR, Hahn CG, Siegel SJ. Juvenile exposure to ketamine causes delayed emergence of EEG abnormalities during adulthood in mice. Drug and Alcohol Dependence. 134: 123-7. PMID 24210161 DOI: 10.1016/J.Drugalcdep.2013.09.017 |
0.406 |
|
| 2013 |
Lin RE, Ambler L, Billingslea EN, Suh J, Batheja S, Tatard-Leitman V, Featherstone RE, Siegel SJ. Electroencephalographic and early communicative abnormalities in Brattleboro rats. Physiological Reports. 1: e00100. PMID 24303172 DOI: 10.1002/Phy2.100 |
0.704 |
|
| 2013 |
Siegel SJ. Capacity, confidentiality and consequences: balancing responsible medical care with mental health law. Current Psychiatry Reports. 15: 380. PMID 23881711 DOI: 10.1007/s11920-013-0380-5 |
0.328 |
|
| 2013 |
Siegel SJ, Talpos JC, Geyer MA. Animal models and measures of perceptual processing in schizophrenia. Neuroscience and Biobehavioral Reviews. 37: 2092-8. PMID 23867801 DOI: 10.1016/j.neubiorev.2013.06.016 |
0.353 |
|
| 2013 |
Saunders JA, Tatard-Leitman VM, Suh J, Billingslea EN, Roberts TP, Siegel SJ. Knockout of NMDA receptors in parvalbumin interneurons recreates autism-like phenotypes. Autism Research : Official Journal of the International Society For Autism Research. 6: 69-77. PMID 23441094 DOI: 10.1002/Aur.1264 |
0.632 |
|
| 2013 |
Featherstone RE, M Tatard-Leitman V, Suh JD, Lin R, Lucki I, Siegel SJ. Electrophysiological and behavioral responses to ketamine in mice with reduced Akt1 expression. Psychopharmacology. 227: 639-49. PMID 23392353 DOI: 10.1007/S00213-013-2997-9 |
0.73 |
|
| 2013 |
De Rojas JO, Saunders JA, Luminais C, Hamilton RH, Siegel SJ. Electroencephalographic changes following direct current deep brain stimulation of auditory cortex: a new model for investigating neuromodulation. Neurosurgery. 72: 267-75; discussion 2. PMID 23149971 DOI: 10.1227/Neu.0B013E31827B93C0 |
0.547 |
|
| 2013 |
Siegel SJ, Nagy L, Skarsfeldt T, Pierce M, Neill CO, Lin R, Langhamer L, Kordower JH. Ropinirole Implants Reverse MPTP-Induced Parkinsonism in Rhesus Monkeys Pharmacology &Amp; Pharmacy. 4: 1-8. DOI: 10.4236/PP.2013.43A001 |
0.623 |
|
| 2012 |
Rabin CR, Siegel SJ. Delivery systems and dosing for antipsychotics. Handbook of Experimental Pharmacology. 267-98. PMID 23129336 DOI: 10.1007/978-3-642-25761-2_11 |
0.368 |
|
| 2012 |
Featherstone RE, Phillips JM, Thieu T, Ehrlichman RS, Halene TB, Leiser SC, Christian E, Johnson E, Lerman C, Siegel SJ. Nicotine receptor subtype-specific effects on auditory evoked oscillations and potentials. Plos One. 7: e39775. PMID 22911690 DOI: 10.1371/Journal.Pone.0039775 |
0.795 |
|
| 2012 |
Moessnang C, Habel U, Schneider F, Siegel SJ. The electrophysiological signature of motivational salience in mice and implications for schizophrenia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 2846-54. PMID 22910459 DOI: 10.1038/npp.2012.156 |
0.496 |
|
| 2012 |
Gandal MJ, Sisti J, Klook K, Ortinski PI, Leitman V, Liang Y, Thieu T, Anderson R, Pierce RC, Jonak G, Gur RE, Carlson G, Siegel SJ. GABAB-mediated rescue of altered excitatory-inhibitory balance, gamma synchrony and behavioral deficits following constitutive NMDAR-hypofunction. Translational Psychiatry. 2: e142. PMID 22806213 DOI: 10.1038/tp.2012.69 |
0.695 |
|
| 2012 |
Saunders JA, Gandal MJ, Roberts TP, Siegel SJ. NMDA antagonist MK801 recreates auditory electrophysiology disruption present in autism and other neurodevelopmental disorders. Behavioural Brain Research. 234: 233-7. PMID 22771812 DOI: 10.1016/J.Bbr.2012.06.032 |
0.746 |
|
| 2012 |
Gandal MJ, Anderson RL, Billingslea EN, Carlson GC, Roberts TP, Siegel SJ. Mice with reduced NMDA receptor expression: more consistent with autism than schizophrenia? Genes, Brain, and Behavior. 11: 740-50. PMID 22726567 DOI: 10.1111/j.1601-183X.2012.00816.x |
0.72 |
|
| 2012 |
Featherstone RE, Liang Y, Saunders JA, Tatard-Leitman VM, Ehrlichman RS, Siegel SJ. Subchronic ketamine treatment leads to permanent changes in EEG, cognition and the astrocytic glutamate transporter EAAT2 in mice. Neurobiology of Disease. 47: 338-46. PMID 22627142 DOI: 10.1016/J.Nbd.2012.05.003 |
0.805 |
|
| 2012 |
Cao YA, Featherstone RE, Gandal MJ, Liang Y, Jutzeler C, Saunders J, Tatard-Leitman V, Chen J, Weinberger DR, Lerman C, Siegel SJ. Nicotine normalizes event related potentials in COMT-Val-tg mice and increases gamma and theta spectral density. Behavioral Neuroscience. 126: 332-43. PMID 22309446 DOI: 10.1037/A0027047 |
0.738 |
|
| 2012 |
Liao W, Gandal MJ, Ehrlichman RS, Siegel SJ, Carlson GC. MeCP2+/- mouse model of RTT reproduces auditory phenotypes associated with Rett syndrome and replicate select EEG endophenotypes of autism spectrum disorder. Neurobiology of Disease. 46: 88-92. PMID 22249109 DOI: 10.1016/J.Nbd.2011.12.048 |
0.795 |
|
| 2012 |
Saunders JA, Gandal MJ, Siegel SJ. NMDA antagonists recreate signal-to-noise ratio and timing perturbations present in schizophrenia. Neurobiology of Disease. 46: 93-100. PMID 22245663 DOI: 10.1016/J.Nbd.2011.12.049 |
0.713 |
|
| 2012 |
Gandal MJ, Edgar JC, Klook K, Siegel SJ. Gamma synchrony: towards a translational biomarker for the treatment-resistant symptoms of schizophrenia. Neuropharmacology. 62: 1504-18. PMID 21349276 DOI: 10.1016/j.neuropharm.2011.02.007 |
0.69 |
|
| 2012 |
Rojas J, Hamilton R, Luminais C, Siegel S. Investigating the Neurophysiological Effects of Direct Current Stimulation (IN6-1.005) Neurology. 78: IN6-1.005-IN6-1.005. DOI: 10.1212/Wnl.78.1_Meetingabstracts.In6-1.005 |
0.359 |
|
| 2012 |
Roberts TPL, Gandal M, Siegel SJ, Vianney–Rodrigues P, Welsh JP. Autism spectrum disorders Translational Neuroscience: Applications in Psychiatry, Neurology, and Neurodevelopmental Disorders. 273-302. DOI: 10.1017/CBO9780511980053.017 |
0.543 |
|
| 2011 |
Mehta MV, Gandal MJ, Siegel SJ. mGluR5-antagonist mediated reversal of elevated stereotyped, repetitive behaviors in the VPA model of autism. Plos One. 6: e26077. PMID 22016815 DOI: 10.1371/journal.pone.0026077 |
0.667 |
|
| 2011 |
Carlson GC, Talbot K, Halene TB, Gandal MJ, Kazi HA, Schlosser L, Phung QH, Gur RE, Arnold SE, Siegel SJ. Dysbindin-1 mutant mice implicate reduced fast-phasic inhibition as a final common disease mechanism in schizophrenia. Proceedings of the National Academy of Sciences of the United States of America. 108: E962-70. PMID 21969553 DOI: 10.1073/Pnas.1109625108 |
0.699 |
|
| 2011 |
Berger AK, Green T, Siegel SJ, Nestler EJ, Hammer RP. cAMP response element binding protein phosphorylation in nucleus accumbens underlies sustained recovery of sensorimotor gating following repeated D₂-like receptor agonist treatment in rats. Biological Psychiatry. 69: 288-94. PMID 21035786 DOI: 10.1016/J.Biopsych.2010.08.032 |
0.357 |
|
| 2010 |
Rabin CR, Siegel SJ. Antipsychotic dosing and drug delivery. Current Topics in Behavioral Neurosciences. 4: 141-77. PMID 21312400 DOI: 10.1007/7854_2010_46 |
0.351 |
|
| 2010 |
Gandal MJ, Edgar JC, Ehrlichman RS, Mehta M, Roberts TP, Siegel SJ. Validating γ oscillations and delayed auditory responses as translational biomarkers of autism. Biological Psychiatry. 68: 1100-6. PMID 21130222 DOI: 10.1016/J.Biopsych.2010.09.031 |
0.814 |
|
| 2010 |
Amann LC, Gandal MJ, Halene TB, Ehrlichman RS, White SL, McCarren HS, Siegel SJ. Mouse behavioral endophenotypes for schizophrenia. Brain Research Bulletin. 83: 147-61. PMID 20433908 DOI: 10.1016/J.Brainresbull.2010.04.008 |
0.826 |
|
| 2010 |
Siegel SJ. Resurgence of long-acting antipsychotic formulations. Current Psychiatry Reports. 12: 276-8. PMID 20424976 DOI: 10.1007/s11920-010-0121-y |
0.316 |
|
| 2010 |
Amann LC, Gandal MJ, Lin R, Liang Y, Siegel SJ. In vitro-in vivo correlations of scalable PLGA-risperidone implants for the treatment of schizophrenia. Pharmaceutical Research. 27: 1730-7. PMID 20422263 DOI: 10.1007/s11095-010-0152-4 |
0.747 |
|
| 2010 |
Rudnick ND, Strasser AA, Phillips JM, Jepson C, Patterson F, Frey JM, Turetsky BI, Lerman C, Siegel SJ. Mouse model predicts effects of smoking and varenicline on event-related potentials in humans. Nicotine & Tobacco Research : Official Journal of the Society For Research On Nicotine and Tobacco. 12: 589-97. PMID 20395358 DOI: 10.1093/Ntr/Ntq049 |
0.782 |
|
| 2010 |
Loughead J, Ray R, Wileyto EP, Ruparel K, Sanborn P, Siegel S, Gur RC, Lerman C. Effects of the alpha4beta2 partial agonist varenicline on brain activity and working memory in abstinent smokers. Biological Psychiatry. 67: 715-21. PMID 20207347 DOI: 10.1016/J.Biopsych.2010.01.016 |
0.344 |
|
| 2010 |
Satterthwaite TD, Wolf DH, Loughead J, Ruparel K, Valdez JN, Siegel SJ, Kohler CG, Gur RE, Gur RC. Association of enhanced limbic response to threat with decreased cortical facial recognition memory response in schizophrenia. The American Journal of Psychiatry. 167: 418-26. PMID 20194482 DOI: 10.1176/Appi.Ajp.2009.09060808 |
0.398 |
|
| 2010 |
Patterson F, Jepson C, Loughead J, Perkins K, Strasser AA, Siegel S, Frey J, Gur R, Lerman C. Working memory deficits predict short-term smoking resumption following brief abstinence Drug and Alcohol Dependence. 106: 61-64. PMID 19733449 DOI: 10.1016/J.Drugalcdep.2009.07.020 |
0.303 |
|
| 2010 |
Lazarewicz MT, Ehrlichman RS, Maxwell CR, Gandal MJ, Finkel LH, Siegel SJ. Ketamine modulates theta and gamma oscillations. Journal of Cognitive Neuroscience. 22: 1452-64. PMID 19583475 DOI: 10.1162/Jocn.2009.21305 |
0.81 |
|
| 2009 |
Ehrlichman RS, Luminais SN, White SL, Rudnick ND, Ma N, Dow HC, Kreibich AS, Abel T, Brodkin ES, Hahn CG, Siegel SJ. Neuregulin 1 transgenic mice display reduced mismatch negativity, contextual fear conditioning and social interactions. Brain Research. 1294: 116-27. PMID 19643092 DOI: 10.1016/J.Brainres.2009.07.065 |
0.81 |
|
| 2009 |
Halene TB, Talmud J, Jonak GJ, Schneider F, Siegel SJ. Predator odor modulates auditory event-related potentials in mice. Neuroreport. 20: 1260-4. PMID 19625986 DOI: 10.1097/WNR.0b013e3283300cde |
0.442 |
|
| 2009 |
Bodarky CL, Halene TB, Ehrlichman RS, Banerjee A, Ray R, Hahn CG, Jonak G, Siegel SJ. Novel environment and GABA agonists alter event-related potentials in N-methyl-D-aspartate NR1 hypomorphic and wild-type mice. The Journal of Pharmacology and Experimental Therapeutics. 331: 308-18. PMID 19602553 DOI: 10.1124/Jpet.109.150938 |
0.784 |
|
| 2009 |
Halene TB, Ehrlichman RS, Liang Y, Christian EP, Jonak GJ, Gur TL, Blendy JA, Dow HC, Brodkin ES, Schneider F, Gur RC, Siegel SJ. Assessment of NMDA receptor NR1 subunit hypofunction in mice as a model for schizophrenia. Genes, Brain, and Behavior. 8: 661-75. PMID 19563516 DOI: 10.1111/J.1601-183X.2009.00504.X |
0.795 |
|
| 2009 |
Amann LC, Halene TB, Ehrlichman RS, Luminais SN, Ma N, Abel T, Siegel SJ. Chronic ketamine impairs fear conditioning and produces long-lasting reductions in auditory evoked potentials. Neurobiology of Disease. 35: 311-7. PMID 19467327 DOI: 10.1016/J.Nbd.2009.05.012 |
0.775 |
|
| 2009 |
Ehrlichman RS, Gandal MJ, Maxwell CR, Lazarewicz MT, Finkel LH, Contreras D, Turetsky BI, Siegel SJ. N-methyl-d-aspartic acid receptor antagonist-induced frequency oscillations in mice recreate pattern of electrophysiological deficits in schizophrenia. Neuroscience. 158: 705-12. PMID 19015010 DOI: 10.1016/J.Neuroscience.2008.10.031 |
0.82 |
|
| 2009 |
Turetsky BI, Bilker WB, Siegel SJ, Kohler CG, Gur RE. Profile of auditory information-processing deficits in schizophrenia. Psychiatry Research. 165: 27-37. PMID 18990453 DOI: 10.1016/J.Psychres.2008.04.013 |
0.448 |
|
| 2009 |
Rudnick ND, Koehler C, Picciotto MR, Siegel SJ. Role of beta2-containing nicotinic acetylcholine receptors in auditory event-related potentials. Psychopharmacology. 202: 745-51. PMID 18931833 DOI: 10.1007/s00213-008-1358-6 |
0.798 |
|
| 2009 |
Patterson F, Jepson C, Strasser AA, Loughead J, Perkins KA, Gur RC, Frey JM, Siegel S, Lerman C. Varenicline improves mood and cognition during smoking abstinence. Biological Psychiatry. 65: 144-9. PMID 18842256 DOI: 10.1016/J.Biopsych.2008.08.028 |
0.315 |
|
| 2008 |
Gandal MJ, Ehrlichman RS, Rudnick ND, Siegel SJ. A novel electrophysiological model of chemotherapy-induced cognitive impairments in mice. Neuroscience. 157: 95-104. PMID 18835334 DOI: 10.1016/J.Neuroscience.2008.08.060 |
0.792 |
|
| 2008 |
Amann LC, Phillips JM, Halene TB, Siegel SJ. Male and female mice differ for baseline and nicotine-induced event related potentials. Behavioral Neuroscience. 122: 982-90. PMID 18823155 DOI: 10.1037/a0012995 |
0.538 |
|
| 2008 |
Halene TB, Siegel SJ. Antipsychotic-like properties of phosphodiesterase 4 inhibitors: evaluation of 4-(3-butoxy-4-methoxybenzyl)-2-imidazolidinone (RO-20-1724) with auditory event-related potentials and prepulse inhibition of startle. The Journal of Pharmacology and Experimental Therapeutics. 326: 230-9. PMID 18420599 DOI: 10.1124/jpet.108.138586 |
0.439 |
|
| 2008 |
Ehrlichman RS, Maxwell CR, Majumdar S, Siegel SJ. Deviance-elicited changes in event-related potentials are attenuated by ketamine in mice. Journal of Cognitive Neuroscience. 20: 1403-14. PMID 18303985 DOI: 10.1162/Jocn.2008.20097 |
0.823 |
|
| 2008 |
Kelly MP, Cheung YF, Favilla C, Siegel SJ, Kanes SJ, Houslay MD, Abel T. Constitutive activation of the G-protein subunit Galphas within forebrain neurons causes PKA-dependent alterations in fear conditioning and cortical Arc mRNA expression. Learning & Memory (Cold Spring Harbor, N.Y.). 15: 75-83. PMID 18230676 DOI: 10.1101/Lm.723708 |
0.371 |
|
| 2008 |
Majewski-Tiedeken CR, Rabin CR, Siegel SJ. Ketamine exposure in adult mice leads to increased cell death in C3H, DBA2 and FVB inbred mouse strains. Drug and Alcohol Dependence. 92: 217-27. PMID 17920787 DOI: 10.1016/j.drugalcdep.2007.08.009 |
0.342 |
|
| 2008 |
Rabin C, Liang Y, Ehrlichman RS, Budhian A, Metzger KL, Majewski-Tiedeken C, Winey KI, Siegel SJ. In vitro and in vivo demonstration of risperidone implants in mice. Schizophrenia Research. 98: 66-78. PMID 17765477 DOI: 10.1016/J.Schres.2007.08.003 |
0.739 |
|
| 2007 |
Phillips JM, Siegel SJ, Shields AE, Patterson F, Gould TJ, Strasser AA, Ray R, Pinto A, Audrain-McGovern J, Rukstalis M, Perkins KA, Blendy JA, Lerman C. Translating basic science to improve pharmacotherapy for nicotine dependence. Nicotine & Tobacco Research : Official Journal of the Society For Research On Nicotine and Tobacco. 9: S583-98. PMID 18067034 DOI: 10.1080/14622200701691755 |
0.468 |
|
| 2007 |
Halene TB, Siegel SJ. PDE inhibitors in psychiatry--future options for dementia, depression and schizophrenia? Drug Discovery Today. 12: 870-8. PMID 17933689 DOI: 10.1016/j.drudis.2007.07.023 |
0.323 |
|
| 2007 |
Hans ML, Maxwell C, Ehrlichman RS, Metzger K, Liang Y, Siegel SJ, Lowman AM. Evaluation of in vitro release and in vivo efficacy of mPEG-PLA-haloperidol conjugate micelle-like structures. Journal of Biomedical Materials Research. Part B, Applied Biomaterials. 83: 422-30. PMID 17415770 DOI: 10.1002/Jbm.B.30812 |
0.755 |
|
| 2007 |
Gur RE, Turetsky BI, Loughead J, Snyder W, Kohler C, Elliott M, Pratiwadi R, Ragland JD, Bilker WB, Siegel SJ, Kanes SJ, Arnold SE, Gur RC. Visual attention circuitry in schizophrenia investigated with oddball event-related functional magnetic resonance imaging. The American Journal of Psychiatry. 164: 442-9. PMID 17329469 DOI: 10.1176/Ajp.2007.164.3.442 |
0.371 |
|
| 2007 |
Phillips JM, Ehrlichman RS, Siegel SJ. Mecamylamine blocks nicotine-induced enhancement of the P20 auditory event-related potential and evoked gamma. Neuroscience. 144: 1314-23. PMID 17184927 DOI: 10.1016/J.Neuroscience.2006.11.003 |
0.813 |
|
| 2007 |
Metzger KL, Shoemaker JM, Kahn JB, Maxwell CR, Liang Y, Tokarczyk J, Kanes SJ, Hans M, Lowman AM, Dan N, Winey KI, Swerdlow NR, Siegel SJ. Pharmacokinetic and behavioral characterization of a long-term antipsychotic delivery system in rodents and rabbits. Psychopharmacology. 190: 201-11. PMID 17119931 DOI: 10.1007/S00213-006-0616-8 |
0.653 |
|
| 2007 |
Kanes SJ, Tokarczyk J, Siegel SJ, Bilker W, Abel T, Kelly MP. Rolipram: a specific phosphodiesterase 4 inhibitor with potential antipsychotic activity. Neuroscience. 144: 239-46. PMID 17081698 DOI: 10.1016/J.Neuroscience.2006.09.026 |
0.433 |
|
| 2007 |
Kelly MP, Isiegas C, Cheung YF, Tokarczyk J, Yang X, Esposito MF, Rapoport DA, Fabian SA, Siegel SJ, Wand G, Houslay MD, Kanes SJ, Abel T. Constitutive activation of Galphas within forebrain neurons causes deficits in sensorimotor gating because of PKA-dependent decreases in cAMP. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 32: 577-88. PMID 16738544 DOI: 10.1038/Sj.Npp.1301099 |
0.417 |
|
| 2007 |
Metzger KL, Maxwell CR, Liang Y, Siegel SJ. Effects of nicotine vary across two auditory evoked potentials in the mouse. Biological Psychiatry. 61: 23-30. PMID 16497274 DOI: 10.1016/J.Biopsych.2005.12.011 |
0.683 |
|
| 2006 |
Moberg PJ, Arnold SE, Doty RL, Gur RE, Balderston CC, Roalf DR, Gur RC, Kohler CG, Kanes SJ, Siegel SJ, Turetsky BI. Olfactory functioning in schizophrenia: relationship to clinical, neuropsychological, and volumetric MRI measures. Journal of Clinical and Experimental Neuropsychology. 28: 1444-61. PMID 17050269 DOI: 10.1080/13803390500434409 |
0.354 |
|
| 2006 |
Irani F, Platek SM, Panyavin IS, Calkins ME, Kohler C, Siegel SJ, Schachter M, Gur RE, Gur RC. Self-face recognition and theory of mind in patients with schizophrenia and first-degree relatives. Schizophrenia Research. 88: 151-60. PMID 16979876 DOI: 10.1016/J.Schres.2006.07.016 |
0.371 |
|
| 2006 |
Roalf DR, Turetsky BI, Owzar K, Balderston CC, Johnson SC, Brensinger CM, Gur RE, Siegel SJ, Moberg PJ. Unirhinal olfactory function in schizophrenia patients and first-degree relatives. The Journal of Neuropsychiatry and Clinical Neurosciences. 18: 389-96. PMID 16963589 DOI: 10.1176/jnp.2006.18.3.389 |
0.308 |
|
| 2006 |
Hahn CG, Wang HY, Cho DS, Talbot K, Gur RE, Berrettini WH, Bakshi K, Kamins J, Borgmann-Winter KE, Siegel SJ, Gallop RJ, Arnold SE. Altered neuregulin 1-erbB4 signaling contributes to NMDA receptor hypofunction in schizophrenia. Nature Medicine. 12: 824-8. PMID 16767099 DOI: 10.1038/Nm1418 |
0.429 |
|
| 2006 |
Maxwell CR, Liang Y, Kelly MP, Kanes SJ, Abel T, Siegel SJ. Mice expressing constitutively active Gsalpha exhibit stimulus encoding deficits similar to those observed in schizophrenia patients. Neuroscience. 141: 1257-64. PMID 16750890 DOI: 10.1016/J.Neuroscience.2006.04.028 |
0.71 |
|
| 2006 |
Siegel SJ, Irani F, Brensinger CM, Kohler CG, Bilker WB, Ragland JD, Kanes SJ, Gur RC, Gur RE. Prognostic variables at intake and long-term level of function in schizophrenia. The American Journal of Psychiatry. 163: 433-41. PMID 16513864 DOI: 10.1176/Appi.Ajp.163.3.433 |
0.318 |
|
| 2006 |
Gur RE, Kohler CG, Ragland JD, Siegel SJ, Lesko K, Bilker WB, Gur RC. Flat affect in schizophrenia: relation to emotion processing and neurocognitive measures. Schizophrenia Bulletin. 32: 279-87. PMID 16452608 DOI: 10.1093/Schbul/Sbj041 |
0.313 |
|
| 2006 |
Maxwell CR, Ehrlichman RS, Liang Y, Trief D, Kanes SJ, Karp J, Siegel SJ. Ketamine produces lasting disruptions in encoding of sensory stimuli. The Journal of Pharmacology and Experimental Therapeutics. 316: 315-24. PMID 16192313 DOI: 10.1124/Jpet.105.091199 |
0.814 |
|
| 2006 |
Maxwell CR, Ehrlichman RS, Liang Y, Gettes DR, Evans DL, Kanes SJ, Abel T, Karp J, Siegel SJ. Corticosterone modulates auditory gating in mouse. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 897-903. PMID 16123740 DOI: 10.1038/Sj.Npp.1300879 |
0.798 |
|
| 2005 |
Ragland JD, Gur RC, Valdez JN, Loughead J, Elliott M, Kohler C, Kanes S, Siegel SJ, Moelter ST, Gur RE. Levels-of-processing effect on frontotemporal function in schizophrenia during word encoding and recognition. The American Journal of Psychiatry. 162: 1840-8. PMID 16199830 DOI: 10.1176/Appi.Ajp.162.10.1840 |
0.352 |
|
| 2005 |
Davis JA, James JR, Siegel SJ, Gould TJ. Withdrawal from chronic nicotine administration impairs contextual fear conditioning in C57BL/6 mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 8708-13. PMID 16177040 DOI: 10.1523/Jneurosci.2853-05.2005 |
0.31 |
|
| 2005 |
Siegel SJ, Maxwell CR, Majumdar S, Trief DF, Lerman C, Gur RE, Kanes SJ, Liang Y. Monoamine reuptake inhibition and nicotine receptor antagonism reduce amplitude and gating of auditory evoked potentials. Neuroscience. 133: 729-38. PMID 15908134 DOI: 10.1016/J.Neuroscience.2005.03.027 |
0.712 |
|
| 2005 |
Frankel WN, Beyer B, Maxwell CR, Pretel S, Letts VA, Siegel SJ. Development of a new genetic model for absence epilepsy: spike-wave seizures in C3H/He and backcross mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 3452-8. PMID 15800200 DOI: 10.1523/Jneurosci.0231-05.2005 |
0.64 |
|
| 2004 |
Maxwell CR, Kanes SJ, Abel T, Siegel SJ. Phosphodiesterase inhibitors: a novel mechanism for receptor-independent antipsychotic medications. Neuroscience. 129: 101-7. PMID 15489033 DOI: 10.1016/J.Neuroscience.2004.07.038 |
0.701 |
|
| 2004 |
Irani F, Dankert M, Siegel SJ. Patient and family attitudes toward schizophrenia treatment. Current Psychiatry Reports. 6: 283-8. PMID 15260944 DOI: 10.1007/S11920-004-0078-9 |
0.322 |
|
| 2004 |
Connolly PM, Maxwell C, Liang Y, Kahn JB, Kanes SJ, Abel T, Gur RE, Turetsky BI, Siegel SJ. The effects of ketamine vary among inbred mouse strains and mimic schizophrenia for the P80, but not P20 or N40 auditory ERP components. Neurochemical Research. 29: 1179-88. PMID 15176475 DOI: 10.1023/B:Nere.0000023605.68408.Fb |
0.714 |
|
| 2004 |
Talbot K, Eidem WL, Tinsley CL, Benson MA, Thompson EW, Smith RJ, Hahn CG, Siegel SJ, Trojanowski JQ, Gur RE, Blake DJ, Arnold SE. Dysbindin-1 is reduced in intrinsic, glutamatergic terminals of the hippocampal formation in schizophrenia. The Journal of Clinical Investigation. 113: 1353-63. PMID 15124027 DOI: 10.1172/Jci20425 |
0.408 |
|
| 2004 |
Gelber EI, Kohler CG, Bilker WB, Gur RC, Brensinger C, Siegel SJ, Gur RE. Symptom and demographic profiles in first-episode schizophrenia. Schizophrenia Research. 67: 185-94. PMID 14984877 DOI: 10.1016/S0920-9964(03)00083-5 |
0.38 |
|
| 2004 |
Maxwell CR, Liang Y, Weightman BD, Kanes SJ, Abel T, Gur RE, Turetsky BI, Bilker WB, Lenox RH, Siegel SJ. Effects of chronic olanzapine and haloperidol differ on the mouse N1 auditory evoked potential. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 739-46. PMID 14735128 DOI: 10.1038/Sj.Npp.1300376 |
0.712 |
|
| 2004 |
Gould TJ, Bizily SP, Tokarczyk J, Kelly MP, Siegel SJ, Kanes SJ, Abel T. Sensorimotor gating deficits in transgenic mice expressing a constitutively active form of Gs alpha. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 494-501. PMID 14694347 DOI: 10.1038/Sj.Npp.1300309 |
0.417 |
|
| 2003 |
Ragland JD, Moelter ST, McGrath C, Hill SK, Gur RE, Bilker WB, Siegel SJ, Gur RC. Levels-of-processing effect on word recognition in schizophrenia. Biological Psychiatry. 54: 1154-61. PMID 14643082 DOI: 10.1016/S0006-3223(03)00235-X |
0.319 |
|
| 2003 |
Connolly PM, Maxwell CR, Kanes SJ, Abel T, Liang Y, Tokarczyk J, Bilker WB, Turetsky BI, Gur RE, Siegel SJ. Inhibition of auditory evoked potentials and prepulse inhibition of startle in DBA/2J and DBA/2Hsd inbred mouse substrains. Brain Research. 992: 85-95. PMID 14604776 DOI: 10.1016/J.Brainres.2003.08.035 |
0.696 |
|
| 2003 |
Gur RE, Kohler C, Ragland JD, Siegel SJ, Bilker WB, Loughead J, Phend N, Gur RC. Neurocognitive performance and clinical changes in olanzapine-treated patients with schizophrenia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 2029-36. PMID 12902996 DOI: 10.1038/Sj.Npp.1300275 |
0.371 |
|
| 2003 |
Siegel SJ, Connolly P, Liang Y, Lenox RH, Gur RE, Bilker WB, Kanes SJ, Turetsky BI. Effects of strain, novelty, and NMDA blockade on auditory-evoked potentials in mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 675-82. PMID 12655312 DOI: 10.1038/Sj.Npp.1300087 |
0.442 |
|
| 2002 |
Siegel SJ. Increased patient autonomy through long-term antipsychotic delivery systems for the treatment of schizophrenia. Expert Review of Neurotherapeutics. 2: 771-3. PMID 19810909 DOI: 10.1586/14737175.2.6.771 |
0.345 |
|
| 2002 |
Siegel SJ, Winey KI, Gur RE, Lenox RH, Bilker WB, Ikeda D, Gandhi N, Zhang WX. Surgically implantable long-term antipsychotic delivery systems for the treatment of schizophrenia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 26: 817-23. PMID 12007752 DOI: 10.1016/S0893-133X(01)00426-2 |
0.308 |
|
| 2001 |
Gur RC, Ragland JD, Moberg PJ, Bilker WB, Kohler C, Siegel SJ, Gur RE. Computerized neurocognitive scanning: II. The profile of schizophrenia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 25: 777-88. PMID 11682261 DOI: 10.1016/S0893-133X(01)00279-2 |
0.392 |
|
| 1996 |
Gazzaley AH, Siegel SJ, Kordower JH, Mufson EJ, Morrison JH. Circuit-specific alterations of N-methyl-D-aspartate receptor subunit 1 in the dentate gyrus of aged monkeys. Proceedings of the National Academy of Sciences of the United States of America. 93: 3121-5. PMID 8610179 DOI: 10.1073/Pnas.93.7.3121 |
0.655 |
|
| 1996 |
Morrison JH, Siegel SJ, Gazzaley AH, Huntley GW. ■ REVIEW : Glutamate Receptors: Emerging Links Between Subunit Proteins and Specific Excitatory Circuits in Primate Hippocampus and Neocortex: The Neuroscientist. 2: 272-283. DOI: 10.1177/107385849600200513 |
0.682 |
|
| 1996 |
Morrison JH, Siegel SJ, Gazzaley AH, Huntley GW. Glutamate receptors: Emerging links between subunit proteins and specific excitatory circuits in primate hippocampus and neocortex Neuroscientist. 2: 272-283. |
0.727 |
|
| 1995 |
Siegel SJ, Janssen WG, Tullai JW, Rogers SW, Moran T, Heinemann SF, Morrison JH. Distribution of the excitatory amino acid receptor subunits GluR2(4) in monkey hippocampus and colocalization with subunits GluR5-7 and NMDAR1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 2707-19. PMID 7722624 DOI: 10.1523/Jneurosci.15-04-02707.1995 |
0.484 |
|
| 1994 |
Siegel SJ, Brose N, Janssen WG, Gasic GP, Jahn R, Heinemann SF, Morrison JH. Regional, cellular, and ultrastructural distribution of N-methyl-D-aspartate receptor subunit 1 in monkey hippocampus. Proceedings of the National Academy of Sciences of the United States of America. 91: 564-8. PMID 8290563 DOI: 10.1073/Pnas.91.2.564 |
0.494 |
|
| 1993 |
Siegel SJ, Ginsberg SD, Hof PR, Foote SL, Young WG, Kraemer GW, McKinney WT, Morrison JH. Effects of social deprivation in prepubescent rhesus monkeys: immunohistochemical analysis of the neurofilament protein triplet in the hippocampal formation. Brain Research. 619: 299-305. PMID 8374785 DOI: 10.1016/0006-8993(93)91624-2 |
0.576 |
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