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Saiyong Zhu - Publications

Affiliations: 
Scripps Research Institute, La Jolla, La Jolla, CA, United States 
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37 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Hu Z, Lu Y, Cao J, Lin L, Chen X, Zhou Z, Pu J, Chen G, Ma X, Deng Q, Jin Y, Jiang L, Li Y, Li T, Liu J, ... Zhu S, et al. -acetyltransferase NAT10 controls cell fates via connecting mRNA cytidine acetylation to chromatin signaling. Science Advances. 10: eadh9871. PMID 38215194 DOI: 10.1126/sciadv.adh9871  0.313
2023 Chen X, Lu Y, Wang L, Ma X, Pu J, Lin L, Deng Q, Li Y, Wang W, Jin Y, Hu Z, Zhou Z, Chen G, Jiang L, Wang H, ... ... Zhu S, et al. A fast chemical reprogramming system promotes cell identity transition through a diapause-like state. Nature Cell Biology. 25: 1146-1156. PMID 37550515 DOI: 10.1038/s41556-023-01193-x  0.391
2022 Ma X, Cao J, Zhou Z, Lu Y, Li Q, Jin Y, Chen G, Wang W, Ge W, Chen X, Hu Z, Shu X, Deng Q, Pu J, Liang C, ... ... Zhu S, et al. N-methyladenosine modification-mediated mRNA metabolism is essential for human pancreatic lineage specification and islet organogenesis. Nature Communications. 13: 4148. PMID 35851388 DOI: 10.1038/s41467-022-31698-2  0.311
2022 Ma X, Lu Y, Zhou Z, Li Q, Chen X, Wang W, Jin Y, Hu Z, Chen G, Deng Q, Shang W, Wang H, Fu H, He X, Feng XH, ... Zhu S, et al. Human expandable pancreatic progenitor-derived β cells ameliorate diabetes. Science Advances. 8: eabk1826. PMID 35196077 DOI: 10.1126/sciadv.abk1826  0.388
2021 Wang W, Ren S, Lu Y, Chen X, Qu J, Ma X, Deng Q, Hu Z, Jin Y, Zhou Z, Ge W, Zhu Y, Yang N, Li Q, Pu J, ... ... Zhu S, et al. Inhibition of Syk promotes chemical reprogramming of fibroblasts via metabolic rewiring and H S production. The Embo Journal. e106771. PMID 33909912 DOI: 10.15252/embj.2020106771  0.338
2020 Zhou Z, Ma X, Zhu S. Recent advances and potential applications of human pluripotent stem cell-derived pancreatic β cells. Acta Biochimica Et Biophysica Sinica. PMID 32445468 DOI: 10.1093/abbs/gmaa047  0.387
2020 Han X, Zhou Z, Fei L, Sun H, Wang R, Chen Y, Chen H, Wang J, Tang H, Ge W, Zhou Y, Ye F, Jiang M, Wu J, Xiao Y, ... ... Zhu S, et al. Construction of a human cell landscape at single-cell level. Nature. PMID 32214235 DOI: 10.1038/S41586-020-2157-4  0.523
2019 Liu C, Hu X, Li Y, Lu W, Li W, Cao N, Zhu S, Cheng J, Ding S, Zhang M. Conversion of mouse fibroblasts into oligodendrocyte progenitor-like cells through a chemical approach. Journal of Molecular Cell Biology. PMID 30629188 DOI: 10.1093/Jmcb/Mjy088  0.819
2018 Ma X, Chen X, Jin Y, Ge W, Wang W, Kong L, Ji J, Guo X, Huang J, Feng XH, Fu J, Zhu S. Small molecules promote CRISPR-Cpf1-mediated genome editing in human pluripotent stem cells. Nature Communications. 9: 1303. PMID 29610531 DOI: 10.1038/S41467-018-03760-5  0.436
2017 Xu T, Stewart KM, Wang X, Liu K, Xie M, Kyu Ryu J, Li K, Ma T, Wang H, Ni L, Zhu S, Cao N, Zhu D, Zhang Y, Akassoglou K, et al. Metabolic control of TH17 and induced Treg cell balance by an epigenetic mechanism. Nature. PMID 28783731 DOI: 10.1038/Nature23475  0.791
2017 Ma X, Zhu S. Chemical strategies for pancreatic β cell differentiation, reprogramming, and regeneration. Acta Biochimica Et Biophysica Sinica. 1-13. PMID 28338772 DOI: 10.1093/abbs/gmx008  0.355
2017 Ma X, Kong L, Zhu S. Reprogramming cell fates by small molecules. Protein & Cell. PMID 28213718 DOI: 10.1007/S13238-016-0362-6  0.592
2016 Zhang M, Lin YH, Sun YJ, Zhu S, Zheng J, Liu K, Cao N, Li K, Huang Y, Ding S. Pharmacological Reprogramming of Fibroblasts into Neural Stem Cells by Signaling-Directed Transcriptional Activation. Cell Stem Cell. PMID 27133794 DOI: 10.1016/J.Stem.2016.03.020  0.825
2016 Zhu S, Russ HA, Wang X, Zhang M, Ma T, Xu T, Tang S, Hebrok M, Ding S. Human pancreatic beta-like cells converted from fibroblasts. Nature Communications. 7: 10080. PMID 26733021 DOI: 10.1038/Ncomms10080  0.79
2015 Ma T, Li J, Xu Y, Yu C, Xu T, Wang H, Liu K, Cao N, Nie BM, Zhu SY, Xu S, Li K, Wei WG, Wu Y, Guan KL, et al. Atg5-independent autophagy regulates mitochondrial clearance and is essential for iPSC reprogramming. Nature Cell Biology. PMID 26502054 DOI: 10.1038/Ncb3256  0.711
2015 Zhu S, Wang H, Ding S. Reprogramming fibroblasts toward cardiomyocytes, neural stem cells and hepatocytes by cell activation and signaling-directed lineage conversion. Nature Protocols. 10: 959-73. PMID 26042385 DOI: 10.1038/Nprot.2015.059  0.765
2014 Zhu S, Rezvani M, Harbell J, Mattis AN, Wolfe AR, Benet LZ, Willenbring H, Ding S. Mouse liver repopulation with hepatocytes generated from human fibroblasts. Nature. 508: 93-7. PMID 24572354 DOI: 10.1038/Nature13020  0.615
2014 Li K, Zhu S, Russ HA, Xu S, Xu T, Zhang Y, Ma T, Hebrok M, Ding S. Small molecules facilitate the reprogramming of mouse fibroblasts into pancreatic lineages. Cell Stem Cell. 14: 228-36. PMID 24506886 DOI: 10.1016/J.Stem.2014.01.006  0.811
2014 Zhu S, Ambasudhan R, Sun W, Kim HJ, Talantova M, Wang X, Zhang M, Zhang Y, Laurent T, Parker J, Kim HS, Zaremba JD, Saleem S, Sanz-Blasco S, Masliah E, et al. Small molecules enable OCT4-mediated direct reprogramming into expandable human neural stem cells. Cell Research. 24: 126-9. PMID 24296783 DOI: 10.1038/Cr.2013.156  0.802
2012 Westenskow PD, Moreno SK, Krohne TU, Kurihara T, Zhu S, Zhang ZN, Zhao T, Xu Y, Ding S, Friedlander M. Using flow cytometry to compare the dynamics of photoreceptor outer segment phagocytosis in iPS-derived RPE cells. Investigative Ophthalmology & Visual Science. 53: 6282-90. PMID 22871841 DOI: 10.1167/Iovs.12-9721  0.662
2012 Krohne TU, Westenskow PD, Kurihara T, Friedlander DF, Lehmann M, Dorsey AL, Li W, Zhu S, Schultz A, Wang J, Siuzdak G, Ding S, Friedlander M. Generation of retinal pigment epithelial cells from small molecules and OCT4 reprogrammed human induced pluripotent stem cells. Stem Cells Translational Medicine. 1: 96-109. PMID 22532929 DOI: 10.5966/Sctm.2011-0057  0.689
2011 Sun HL, Wang XJ, Ding WH, Zhu SY, Zhao R, Zhang YX, Xin Q, Wang XF, Zhang DP. Identification of an important site for function of the type 2C protein phosphatase ABI2 in abscisic acid signalling in Arabidopsis. Journal of Experimental Botany. 62: 5713-25. PMID 21885535 DOI: 10.1093/Jxb/Err274  0.385
2011 Ambasudhan R, Talantova M, Coleman R, Yuan X, Zhu S, Lipton SA, Ding S. Direct reprogramming of adult human fibroblasts to functional neurons under defined conditions. Cell Stem Cell. 9: 113-8. PMID 21802386 DOI: 10.1016/j.stem.2011.07.002  0.814
2011 Kim J, Efe JA, Zhu S, Talantova M, Yuan X, Wang S, Lipton SA, Zhang K, Ding S. Direct reprogramming of mouse fibroblasts to neural progenitors. Proceedings of the National Academy of Sciences of the United States of America. 108: 7838-43. PMID 21521790 DOI: 10.1073/Pnas.1103113108  0.806
2011 Zhu S, Wei W, Ding S. Chemical strategies for stem cell biology and regenerative medicine. Annual Review of Biomedical Engineering. 13: 73-90. PMID 21513460 DOI: 10.1146/Annurev-Bioeng-071910-124715  0.825
2011 Yuan X, Wan H, Zhao X, Zhu S, Zhou Q, Ding S. Brief report: combined chemical treatment enables Oct4-induced reprogramming from mouse embryonic fibroblasts. Stem Cells (Dayton, Ohio). 29: 549-53. PMID 21425417 DOI: 10.1002/Stem.594  0.779
2011 Zhu S, Ma T, Li J, Ding S. Recent advances in chemically induced reprogramming. Cell Cycle (Georgetown, Tex.). 10: 871-2. PMID 21368574 DOI: 10.4161/Cc.10.6.15035  0.834
2010 Zhu S, Li W, Zhou H, Wei W, Ambasudhan R, Lin T, Kim J, Zhang K, Ding S. Reprogramming of human primary somatic cells by OCT4 and chemical compounds. Cell Stem Cell. 7: 651-5. PMID 21112560 DOI: 10.1016/J.Stem.2010.11.015  0.735
2010 Zhou H, Li W, Zhu S, Joo JY, Do JT, Xiong W, Kim JB, Zhang K, Schöler HR, Ding S. Conversion of mouse epiblast stem cells to an earlier pluripotency state by small molecules. The Journal of Biological Chemistry. 285: 29676-80. PMID 20705612 DOI: 10.1074/Jbc.C110.150599  0.774
2010 Wang XJ, Zhu SY, Lu YF, Zhao R, Xin Q, Wang XF, Zhang DP. Two coupled components of the mitogen-activated protein kinase cascade MdMPK1 and MdMKK1 from apple function in ABA signal transduction. Plant & Cell Physiology. 51: 754-66. PMID 20360020 DOI: 10.1093/Pcp/Pcq037  0.391
2009 Li W, Zhou H, Abujarour R, Zhu S, Young Joo J, Lin T, Hao E, Schöler HR, Hayek A, Ding S. Generation of human-induced pluripotent stem cells in the absence of exogenous Sox2. Stem Cells (Dayton, Ohio). 27: 2992-3000. PMID 19839055 DOI: 10.1002/Stem.240  0.816
2009 Zhou H, Wu S, Joo JY, Zhu S, Han DW, Lin T, Trauger S, Bien G, Yao S, Zhu Y, Siuzdak G, Schöler HR, Duan L, Ding S. Generation of induced pluripotent stem cells using recombinant proteins. Cell Stem Cell. 4: 381-4. PMID 19398399 DOI: 10.1016/J.Stem.2009.04.005  0.781
2009 Li W, Wei W, Zhu S, Zhu J, Shi Y, Lin T, Hao E, Hayek A, Deng H, Ding S. Generation of rat and human induced pluripotent stem cells by combining genetic reprogramming and chemical inhibitors. Cell Stem Cell. 4: 16-9. PMID 19097958 DOI: 10.1016/J.Stem.2008.11.014  0.779
2007 Zhu SY, Yu XC, Wang XJ, Zhao R, Li Y, Fan RC, Shang Y, Du SY, Wang XF, Wu FQ, Xu YH, Zhang XY, Zhang DP. Two calcium-dependent protein kinases, CPK4 and CPK11, regulate abscisic acid signal transduction in Arabidopsis. The Plant Cell. 19: 3019-36. PMID 17921317 DOI: 10.1105/Tpc.107.050666  0.394
2007 Chen S, Takanashi S, Zhang Q, Xiong W, Zhu S, Peters EC, Ding S, Schultz PG. Reversine increases the plasticity of lineage-committed mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. 104: 10482-7. PMID 17566101 DOI: 10.1073/Pnas.0704360104  0.771
2007 Yu XC, Zhu SY, Gao GF, Wang XJ, Zhao R, Zou KQ, Wang XF, Zhang XY, Wu FQ, Peng CC, Zhang DP. Expression of a grape calcium-dependent protein kinase ACPK1 in Arabidopsis thaliana promotes plant growth and confers abscisic acid-hypersensitivity in germination, postgermination growth, and stomatal movement. Plant Molecular Biology. 64: 531-8. PMID 17476573 DOI: 10.1007/S11103-007-9172-9  0.376
2006 Yu XC, Li MJ, Gao GF, Feng HZ, Geng XQ, Peng CC, Zhu SY, Wang XJ, Shen YY, Zhang DP. Abscisic acid stimulates a calcium-dependent protein kinase in grape berry. Plant Physiology. 140: 558-79. PMID 16407437 DOI: 10.1104/Pp.105.074971  0.395
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