Geoffrey M. Thiele - Publications

Affiliations: 
University of Nebraska Medical Center, Omaha, NE, United States 
Area:
Immunology, Toxicology, Cell Biology, Molecular Biology

103 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Luedders BA, Johnson TM, Sayles H, Thiele GM, Mikuls TR, O'Dell JR, England BR. Predictive ability, validity, and responsiveness of the multi-biomarker disease activity score in patients with rheumatoid arthritis initiating methotrexate. Seminars in Arthritis and Rheumatism. 50: 1058-1063. PMID 32911284 DOI: 10.1016/J.Semarthrit.2020.05.019  0.307
2020 Mikuls TR, Edison J, Meeshaw E, Sayles H, England BR, Duryee MJ, Hunter CD, Kelmenson LB, Moss LK, Feser ML, Wagner B, Parish MC, Deane KD, Thiele GM. Autoantibodies to Malondialdehyde-Acetaldehyde Are Detected Prior to Rheumatoid Arthritis Diagnosis and After Other Disease Specific Autoantibodies. Arthritis & Rheumatology (Hoboken, N.J.). PMID 32621635 DOI: 10.1002/Art.41424  0.32
2020 Song YJ, Choi IA, Meylan F, Demoruelle MK, Farley T, Richard AC, Hawley E, Botson J, Hong YJ, Lee EY, Mian SR, Hamilton BC, Thiele GM, Mikuls TR, Gara N, et al. Circulating TNF-like protein 1A (TL1A) is elevated early in rheumatoid arthritis and depends on TNF. Arthritis Research & Therapy. 22: 106. PMID 32381123 DOI: 10.1186/S13075-020-02198-9  0.343
2020 Thiele GM, Duryee MJ, Hunter CD, England BR, Fletcher BS, Daubach EC, Pospisil TP, Klassen LW, Mikuls TR. Immunogenic and inflammatory responses to citrullinated proteins are enhanced following modification with malondialdehyde-acetaldehyde adducts. International Immunopharmacology. 83: 106433. PMID 32224441 DOI: 10.1016/J.Intimp.2020.106433  0.371
2019 Chiou A, England BR, Sayles H, Thiele GM, Duryee MJ, Baker JF, Singh N, Cannon GW, Kerr GS, Reimold A, Gaffo A, Mikuls TR. Coexistent Hyperuricemia and Gout in Rheumatoid Arthritis: Associations with Comorbidities, Disease Activity and Mortality. Arthritis Care & Research. PMID 31074584 DOI: 10.1002/Acr.23926  0.303
2019 Poole JA, Thiele GM, Janike K, Nelson AJ, Duryee MJ, Rentfro K, England BR, Romberger DJ, Carrington JM, Wang D, Swanson BJ, Klassen LW, Mikuls TR. Combined Collagen-Induced Arthritis and Organic Dust-Induced Airway Inflammation to Model Inflammatory Lung Disease in Rheumatoid Arthritis. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 30995344 DOI: 10.1002/Jbmr.3745  0.321
2019 England BR, Duryee MJ, Roul P, Mahajan TD, Singh N, Poole JA, Ascherman DP, Caplan L, Demoruelle MK, Deane KD, Klassen LW, Thiele GM, Mikuls TR. Malondialdehyde-Acetaldehyde Adducts and Antibody Responses in Rheumatoid Arthritis-Interstitial Lung Disease. Arthritis & Rheumatology (Hoboken, N.J.). PMID 30933423 DOI: 10.1002/Art.40900  0.334
2019 Zhao M, Mauer L, Sayles H, Cannon GW, Reimold A, Kerr GS, Baker JF, Thiele GM, England BR, Mikuls TR. HLA-DRB1 Haplotypes, Shared Epitope, and Disease Outcomes in US Veterans with Rheumatoid Arthritis. The Journal of Rheumatology. PMID 30824656 DOI: 10.3899/Jrheum.180724  0.302
2019 Maloley PM, England BR, Sayles H, Thiele GM, Michaud K, Sokolove J, Cannon GW, Reimold AM, Kerr GS, Baker JF, Caplan L, Case AJ, Mikuls TR. Post-traumatic stress disorder and serum cytokine and chemokine concentrations in patients with rheumatoid arthritis. Seminars in Arthritis and Rheumatism. PMID 30777365 DOI: 10.1016/J.Semarthrit.2019.02.002  0.306
2018 Clemens DL, Duryee MJ, Sarmiento C, Chiou A, McGowan JD, Hunter CD, Schlichte SL, Tian J, Klassen LW, O'Dell JR, Thiele GM, Mikuls TR, Zimmerman MC, Anderson DR. Novel Antioxidant Properties of Doxycycline. International Journal of Molecular Sciences. 19. PMID 30562944 DOI: 10.3390/Ijms19124078  0.306
2018 England BR, Sayles H, Michaud K, Thiele GM, Poole JA, Caplan L, Sauer BC, Cannon GW, Reimold A, Kerr GS, Baker JF, Mikuls TR. Chronic lung disease in U.S. Veterans with rheumatoid arthritis and the impact on survival. Clinical Rheumatology. PMID 30280369 DOI: 10.1007/S10067-018-4314-9  0.316
2018 England BR, Thiele GM, Anderson DR, Mikuls TR. Increased cardiovascular risk in rheumatoid arthritis: mechanisms and implications. Bmj (Clinical Research Ed.). 361: k1036. PMID 29685876 DOI: 10.1136/Bmj.K1036  0.322
2018 Mikuls TR, Duryee MJ, England BR, Anderson DR, Hearth-Holmes M, Su K, Michaud K, Payne JB, Sayles H, Hunter C, McGowan JD, Klassen LW, Thiele GM. Malondialdehyde-acetaldehyde antibody concentrations in rheumatoid arthritis and other rheumatic conditions. International Immunopharmacology. 56: 113-118. PMID 29414640 DOI: 10.1016/J.Intimp.2018.01.022  0.339
2017 Duryee MJ, Wiese BM, Bowman JR, Vanlandingham JD, Klassen LW, Thiele GE, Hunter CD, Anderson DR, Mikuls TR, Thiele GM. Liver Tissue Metabolically Transformed by Alcohol Induces Immune Recognition of Liver Self Proteins but not in vivo Inflammation. American Journal of Physiology. Gastrointestinal and Liver Physiology. PMID 29351393 DOI: 10.1152/Ajpgi.00183.2017  0.375
2017 Bright R, Thiele GM, Manavis J, Mikuls TR, Payne JB, Bartold PM. Gingival tissue, an extrasynovial source of malondialdehyde-acetaldehyde adducts, citrullinated and carbamylated proteins. Journal of Periodontal Research. PMID 29044530 DOI: 10.1111/Jre.12486  0.355
2017 Mikuls TR, Duryee MJ, Rahman R, Anderson DR, Sayles HR, Hollins A, Michaud K, Wolfe F, Thiele GE, Sokolove J, Robinson WH, Lingampalli N, Nicholas AP, Talmon GA, Su K, ... ... Thiele GM, et al. Enrichment of malondialdehyde-acetaldehyde antibody in the rheumatoid arthritis joint. Rheumatology (Oxford, England). 56: 1794-1803. PMID 28957552 DOI: 10.1093/Rheumatology/Kex212  0.34
2017 Zimmerman MC, Clemens DL, Duryee MJ, Sarmiento C, Chiou A, Hunter CD, Tian J, Klassen LW, O'Dell JR, Thiele GM, Mikuls TR, Anderson DR. Direct antioxidant properties of methotrexate: Inhibition of malondialdehyde-acetaldehyde-protein adduct formation and superoxide scavenging. Redox Biology. 13: 588-593. PMID 28803127 DOI: 10.1016/J.Redox.2017.07.018  0.384
2017 England BR, Thiele GM, Mikuls TR. Anticitrullinated protein antibodies: origin and role in the pathogenesis of rheumatoid arthritis. Current Opinion in Rheumatology. 29: 57-64. PMID 27755123 DOI: 10.1097/Bor.0000000000000356  0.352
2016 Lange L, Thiele GM, McCracken C, Wang G, Ponder LA, Angeles-Han ST, Rouster-Stevens KA, Hersh AO, Vogler LB, Bohnsack JF, Abramowicz S, Mikuls TR, Prahalad S. Symptoms of periodontitis and antibody responses to Porphyromonas gingivalis in juvenile idiopathic arthritis. Pediatric Rheumatology Online Journal. 14: 8. PMID 26861944 DOI: 10.1186/S12969-016-0068-6  0.33
2016 Mikuls TR, Payne JB, Deane KD, Thiele GM. Autoimmunity of the lung and oral mucosa in a multisystem inflammatory disease: The spark that lights the fire in rheumatoid arthritis? The Journal of Allergy and Clinical Immunology. 137: 28-34. PMID 26768760 DOI: 10.1016/J.Jaci.2015.10.024  0.341
2015 Wampler Muskardin T, Vashisht P, Dorschner JM, Jensen MA, Chrabot BS, Kern M, Curtis JR, Danila MI, Cofield SS, Shadick N, Nigrovic PA, St Clair EW, Bingham CO, Furie R, Robinson W, ... ... Thiele GM, et al. Increased pretreatment serum IFN-β/α ratio predicts non-response to tumour necrosis factor α inhibition in rheumatoid arthritis. Annals of the Rheumatic Diseases. PMID 26546586 DOI: 10.1136/Annrheumdis-2015-208001  0.302
2015 Li S, Yu Y, Yue Y, Liao H, Xie W, Thai J, Mikuls TR, Thiele GM, Duryee MJ, Sayles H, Payne JB, Klassen LW, O'Dell JR, Zhang Z, Su K. Autoantibodies from single circulating plasmablasts react with citrullinated antigens and Porphyromonas gingivalis in rheumatoid arthritis. Arthritis & Rheumatology (Hoboken, N.J.). PMID 26474325 DOI: 10.1002/Art.39455  0.351
2015 Poole JA, Romberger DJ, Wyatt TA, Staab E, VanDeGraaff J, Thiele GM, Dusad A, Klassen LW, Duryee MJ, Mikuls TR, West WW, Wang D, Bailey KL. Age Impacts Pulmonary Inflammation and Systemic Bone Response to Inhaled Organic Dust Exposure. Journal of Toxicology and Environmental Health. Part A. 1-16. PMID 26436836 DOI: 10.1080/15287394.2015.1075165  0.303
2015 Antoniak DT, Duryee MJ, Mikuls TR, Thiele GM, Anderson DR. Aldehyde-modified proteins as mediators of early inflammation in atherosclerotic disease. Free Radical Biology & Medicine. 89: 409-418. PMID 26432980 DOI: 10.1016/J.Freeradbiomed.2015.09.003  0.36
2015 Thiele GM, Duryee MJ, Thiele GE, Tuma DJ, Klassen LW. Review: Precision Cut Liver Slices for the Evaluation of Fatty Liver and Fibrosis. Current Molecular Pharmacology. PMID 26278387 DOI: 10.2174/1874467208666150817112345  0.342
2015 Yu Y, Koehn CD, Yue Y, Li S, Thiele GM, Hearth-Holmes MP, Mikuls TR, O'Dell JR, Klassen LW, Zhang Z, Su K. Celastrol inhibits inflammatory stimuli-induced neutrophil extracellular trap formation. Current Molecular Medicine. 15: 401-10. PMID 25941817 DOI: 10.2174/1566524015666150505160743  0.339
2015 Carson JS, Xiong W, Dale M, Yu F, Duryee MJ, Anderson DR, Thiele GM, Baxter BT. Antibodies against malondialdehyde-acetaldehyde adducts can help identify patients with abdominal aortic aneurysm. Journal of Vascular Surgery. PMID 25724613 DOI: 10.1016/J.Jvs.2014.08.117  0.311
2015 Payne JB, Golub LM, Thiele GM, Mikuls TR. The Link Between Periodontitis and Rheumatoid Arthritis: A Periodontist's Perspective. Current Oral Health Reports. 2: 20-29. PMID 25657894 DOI: 10.1007/S40496-014-0040-9  0.327
2015 Thiele GM, Duryee MJ, Anderson DR, Klassen LW, Mohring SM, Young KA, Benissan-Messan D, Sayles H, Dusad A, Hunter CD, Sokolove J, Robinson WH, O'Dell JR, Nicholas AP, Tuma DJ, et al. Malondialdehyde-acetaldehyde adducts and anti-malondialdehyde-acetaldehyde antibodies in rheumatoid arthritis. Arthritis & Rheumatology (Hoboken, N.J.). 67: 645-55. PMID 25417811 DOI: 10.1002/Art.38969  0.356
2015 Gonzalez SM, Payne JB, Yu F, Thiele GM, Erickson AR, Johnson PG, Schmid MJ, Cannon GW, Kerr GS, Reimold AM, Sokolove J, Robinson WH, Mikuls TR. Alveolar bone loss is associated with circulating anti-citrullinated protein antibody (ACPA) in patients with rheumatoid arthritis. Journal of Periodontology. 86: 222-31. PMID 25299390 DOI: 10.1902/Jop.2014.140425  0.356
2014 McVicker BL, Thiele GM, Tuma DJ, Casey CA. Hepatocyte-mediated cytotoxicity and host defense mechanisms in the alcohol-injured liver. Hepatology International. 8: 432-8. PMID 26201322 DOI: 10.1007/S12072-013-9511-7  0.378
2014 Anderson DR, Duryee MJ, Shurmur SW, Um JY, Bussey WD, Hunter CD, Garvin RP, Sayles HR, Mikuls TR, Klassen LW, Thiele GM. Unique antibody responses to malondialdehyde-acetaldehyde (MAA)-protein adducts predict coronary artery disease. Plos One. 9: e107440. PMID 25210746 DOI: 10.1371/Journal.Pone.0107440  0.306
2014 Sokolove J, Johnson DS, Lahey LJ, Wagner CA, Cheng D, Thiele GM, Michaud K, Sayles H, Reimold AM, Caplan L, Cannon GW, Kerr G, Mikuls TR, Robinson WH. Rheumatoid factor as a potentiator of anti-citrullinated protein antibody-mediated inflammation in rheumatoid arthritis. Arthritis & Rheumatology (Hoboken, N.J.). 66: 813-21. PMID 24757134 DOI: 10.1002/Art.38307  0.363
2014 Kwon HJ, Won YS, Park O, Chang B, Duryee MJ, Thiele GE, Matsumoto A, Singh S, Abdelmegeed MA, Song BJ, Kawamoto T, Vasiliou V, Thiele GM, Gao B. Aldehyde dehydrogenase 2 deficiency ameliorates alcoholic fatty liver but worsens liver inflammation and fibrosis in mice. Hepatology (Baltimore, Md.). 60: 146-57. PMID 24492981 DOI: 10.1002/Hep.27036  0.337
2014 Duryee MJ, Willis MS, Schaffert CS, Reidelberger RD, Dusad A, Anderson DR, Klassen LW, Thiele GM. Precision-cut liver slices from diet-induced obese rats exposed to ethanol are susceptible to oxidative stress and increased fatty acid synthesis. American Journal of Physiology. Gastrointestinal and Liver Physiology. 306: G208-17. PMID 24284960 DOI: 10.1152/Ajpgi.00124.2013  0.541
2014 Quirke AM, Lugli EB, Wegner N, Hamilton BC, Charles P, Chowdhury M, Ytterberg AJ, Zubarev RA, Potempa J, Culshaw S, Guo Y, Fisher BA, Thiele G, Mikuls TR, Venables PJ. Heightened immune response to autocitrullinated Porphyromonas gingivalis peptidylarginine deiminase: a potential mechanism for breaching immunologic tolerance in rheumatoid arthritis. Annals of the Rheumatic Diseases. 73: 263-9. PMID 23463691 DOI: 10.1136/Annrheumdis-2012-202726  0.353
2014 Hill GE, Gasanova I, Thiele GM. A Mechanism for Inhaled Anesthetic-Induced Solid Organ Injury: Inflammation Open Journal of Anesthesiology. 2: 1. DOI: 10.4236/Ojanes.2014.43012  0.348
2014 Dusad A, Khadge S, Thiele GM, Duryee MJ, Britton HC, Klassen LW, Dafferner AJ, Farrell T, McGuire TR, Hunter CD, Easterling KC, O'Kane KJ, Sharp JG, Talmadge JE. Abstract 1167: Osteolysis, splenic and hepatic extramedullary hematopoiesis, MDSCs, tumor growth, and metastases by orthotopic mammary tumors are increased by alcohol consumption and fatty diets Cancer Research. 74: 1167-1167. DOI: 10.1158/1538-7445.Am2014-1167  0.327
2014 Ptacek J, Hawtin R, Louie B, Evensen E, Cordeiro J, Mittleman B, Atallah M, Cesano A, Cavet G, Bingham CO, Cofield SS, Curtis JR, Danila MI, Furie R, Genovese MC, ... ... Thiele GM, et al. FRI0035 Prediction of TNF Inhibitor Response in Rheumatoid Arthritis Patients Using Single Cell Network Profiling of Intracellular Immune Signaling Annals of the Rheumatic Diseases. 73: 393-394. DOI: 10.1136/Annrheumdis-2014-Eular.2057  0.333
2013 McVicker BL, Thiele GM, Casey CA, Osna NA, Tuma DJ. Susceptibility to T cell-mediated liver injury is enhanced in asialoglycoprotein receptor-deficient mice. International Immunopharmacology. 16: 17-26. PMID 23538026 DOI: 10.1016/J.Intimp.2013.03.012  0.371
2013 Li B, Duysen EG, Froment MT, Masson P, Nachon F, Jiang W, Schopfer LM, Thiele GM, Klassen LW, Cashman J, Williams GR, Lockridge O. Polyclonal antibody to soman-tyrosine. Chemical Research in Toxicology. 26: 584-92. PMID 23469927 DOI: 10.1021/Tx400027N  0.302
2013 Dusad A, Khadge S, Thiele GM, Mikuls TR, Duryee MJ, Britton HC, Klassen LW, Dafferner AJ, Farrell T, McGuire TR, Hunter CD, Easterling KC, O'Kane BJ, Sharp JG, Talmadge JE. High fat and alcoholic diets increase hepatic EMH, osteolysis and spontaneous metastases by orthotopic mammary tumors Journal For Immunotherapy of Cancer. 1: 258. DOI: 10.1186/2051-1426-1-S1-P258  0.324
2012 Mikuls TR, Thiele GM, Deane KD, Payne JB, O'Dell JR, Yu F, Sayles H, Weisman MH, Gregersen PK, Buckner JH, Keating RM, Derber LA, Robinson WH, Holers VM, Norris JM. Porphyromonas gingivalis and disease-related autoantibodies in individuals at increased risk of rheumatoid arthritis. Arthritis and Rheumatism. 64: 3522-30. PMID 22736291 DOI: 10.1002/Art.34595  0.332
2012 Thiele GM, Duryee MJ, Dusad A, Hunter CD, Lacy JP, Anderson DR, Wang D, O'Dell JR, Mikuls TR, Klassen LW. Citrullinated mouse collagen administered to DBA/1J mice in the absence of adjuvant initiates arthritis. International Immunopharmacology. 13: 424-31. PMID 22626832 DOI: 10.1016/J.Intimp.2012.05.007  0.382
2012 Thomes PG, Trambly CS, Thiele GM, Duryee MJ, Fox HS, Haorah J, Donohue TM. Proteasome activity and autophagosome content in liver are reciprocally regulated by ethanol treatment. Biochemical and Biophysical Research Communications. 417: 262-7. PMID 22142844 DOI: 10.1016/J.Bbrc.2011.11.097  0.317
2012 Lugli E, QA, Ytterberg J, Wegner N, Hamilton B, Charles P, Chowdhury M, Thiele G, Mikuls T, Fisher BA, Venables PJ. Autodeimination of Porphyromonas gingivalis peptidylarginine deiminase: a novel antigen in rheumatoid arthritis Annals of the Rheumatic Diseases. 71. DOI: 10.1136/Annrheumdis-2011-201232.2  0.339
2011 Mikuls TR, LeVan TD, Sayles H, Yu F, Caplan L, Cannon GW, Kerr GS, Reimold AM, Johnson DS, Thiele GM. Soluble CD14 and CD14 polymorphisms in rheumatoid arthritis. The Journal of Rheumatology. 38: 2509-16. PMID 21921097 DOI: 10.3899/Jrheum.110378  0.321
2010 Mikuls TR, Gould KA, Bynoté KK, Yu F, Levan TD, Thiele GM, Michaud KD, O'Dell JR, Reimold AM, Hooker R, Caplan L, Johnson DS, Kerr G, Richards JS, Cannon GW, et al. Anticitrullinated protein antibody (ACPA) in rheumatoid arthritis: influence of an interaction between HLA-DRB1 shared epitope and a deletion polymorphism in glutathione S-transferase in a cross-sectional study. Arthritis Research & Therapy. 12: R213. PMID 21087494 DOI: 10.1186/Ar3190  0.337
2010 Thiele GM, Duryee MJ, Willis MS, Tuma DJ, Radio SJ, Hunter CD, Schaffert CS, Klassen LW. Autoimmune hepatitis induced by syngeneic liver cytosolic proteins biotransformed by alcohol metabolites. Alcoholism, Clinical and Experimental Research. 34: 2126-36. PMID 20860619 DOI: 10.1111/J.1530-0277.2010.01309.X  0.591
2010 Quan LD, Purdue PE, Liu XM, Boska MD, Lele SM, Thiele GM, Mikuls TR, Dou H, Goldring SR, Wang D. Development of a macromolecular prodrug for the treatment of inflammatory arthritis: mechanisms involved in arthrotropism and sustained therapeutic efficacy. Arthritis Research & Therapy. 12: R170. PMID 20836843 DOI: 10.1186/Ar3130  0.327
2010 Duryee MJ, Klassen LW, Schaffert CS, Tuma DJ, Hunter CD, Garvin RP, Anderson DR, Thiele GM. Malondialdehyde-acetaldehyde adduct is the dominant epitope after MDA modification of proteins in atherosclerosis. Free Radical Biology & Medicine. 49: 1480-6. PMID 20696236 DOI: 10.1016/J.Freeradbiomed.2010.08.001  0.382
2010 Schaffert CS, Duryee MJ, Bennett RG, DeVeney AL, Tuma DJ, Olinga P, Easterling KC, Thiele GM, Klassen LW. Exposure of precision-cut rat liver slices to ethanol accelerates fibrogenesis. American Journal of Physiology. Gastrointestinal and Liver Physiology. 299: G661-8. PMID 20595623 DOI: 10.1152/Ajpgi.00287.2009  0.337
2010 Miriovsky BJ, Michaud K, Thiele GM, O'Dell JR, Cannon GW, Kerr G, Richards JS, Johnson D, Caplan L, Reimold A, Hooker R, Mikuls TR. Anti-CCP antibody and rheumatoid factor concentrations predict greater disease activity in men with rheumatoid arthritis. Annals of the Rheumatic Diseases. 69: 1292-7. PMID 20439294 DOI: 10.1136/Ard.2009.122739  0.337
2009 Schaffert CS, Duryee MJ, Hunter CD, Hamilton BC, DeVeney AL, Huerter MM, Klassen LW, Thiele GM. Alcohol metabolites and lipopolysaccharide: roles in the development and/or progression of alcoholic liver disease. World Journal of Gastroenterology : Wjg. 15: 1209-18. PMID 19291821 DOI: 10.3748/Wjg.15.1209  0.392
2009 Osna NA, White RL, Thiele GM, Donohue TM. Ethanol metabolism alters major histocompatibility complex class I-restricted antigen presentation in liver cells. Hepatology (Baltimore, Md.). 49: 1308-15. PMID 19195028 DOI: 10.1002/Hep.22787  0.332
2009 Mikuls TR, Payne JB, Reinhardt RA, Thiele GM, Maziarz E, Cannella AC, Holers VM, Kuhn KA, O'Dell JR. Antibody responses to Porphyromonas gingivalis (P. gingivalis) in subjects with rheumatoid arthritis and periodontitis. International Immunopharmacology. 9: 38-42. PMID 18848647 DOI: 10.1016/J.Intimp.2008.09.008  0.324
2008 Klassen LW, Thiele GM, Duryee MJ, Schaffert CS, DeVeney AL, Hunter CD, Olinga P, Tuma DJ. An in vitro method of alcoholic liver injury using precision-cut liver slices from rats. Biochemical Pharmacology. 76: 426-36. PMID 18599023 DOI: 10.1016/J.Bcp.2008.05.012  0.345
2008 Duryee MJ, Klassen LW, Jones BL, Willis MS, Tuma DJ, Thiele GM. Increased immunogenicity to P815 cells modified with malondialdehyde and acetaldehyde. International Immunopharmacology. 8: 1112-8. PMID 18550015 DOI: 10.1016/J.Intimp.2008.03.022  0.565
2008 Thiele GM, Klassen LW, Tuma DJ. Formation and immunological properties of aldehyde-derived protein adducts following alcohol consumption. Methods in Molecular Biology (Clifton, N.J.). 447: 235-57. PMID 18369923 DOI: 10.1007/978-1-59745-242-7_17  0.372
2007 Duryee MJ, Klassen LW, Thiele GM. Immunological response in alcoholic liver disease. World Journal of Gastroenterology. 13: 4938-46. PMID 17854135 DOI: 10.3748/Wjg.V13.I37.4938  0.414
2007 Osna NA, White RL, Todero S, McVicker BL, Thiele GM, Clemens DL, Tuma DJ, Donohue TM. Ethanol-induced oxidative stress suppresses generation of peptides for antigen presentation by hepatoma cells. Hepatology (Baltimore, Md.). 45: 53-61. PMID 17187415 DOI: 10.1002/Hep.21442  0.313
2005 Szabo G, Weinman SA, Gao B, Polyak SJ, Mandrekar P, Thiele GM. RSA 2004: combined basic research satellite symposium - session four: hepatitis virus and alcohol interactions in immunity and liver disease. Alcoholism, Clinical and Experimental Research. 29: 1753-7. PMID 16205377 DOI: 10.1097/01.Alc.0000179319.44684.58  0.341
2005 Mandrekar P, Pruett S, Arteel G, Thiele GM, Szabo G. RSA 2004: Combined Basic Research Satellite Symposium – Session Two: Toll‐Like Receptors and Organ Damage Alcoholism: Clinical and Experimental Research. 29: 1744-1748. PMID 16205375 DOI: 10.1097/01.Alc.0000179315.09591.55  0.323
2005 Hoek J, Thiele GM, Klassen LW, Mandrekar P, Zakhari S, Cook RT, Ray NB, Happel KI, Kolls JK, Kovacs EJ, Szab G. RSA 2004: combined basic research satellite symposium-mechanisms of alcohol-mediated organ and tissue damage: inflammation and immunity and alcohol and mitochondrial metabolism: at the crossroads of life and death session one: alcohol, cellular and organ damage. Alcoholism, Clinical and Experimental Research. 29: 1735-43. PMID 16205374 DOI: 10.1097/01.Alc.0000179313.64522.56  0.32
2005 Thiele GM, Duryee MJ, Freeman TL, Sorrell MF, Willis MS, Tuma DJ, Klassen LW. Rat sinusoidal liver endothelial cells (SECs) produce pro-fibrotic factors in response to adducts formed from the metabolites of ethanol. Biochemical Pharmacology. 70: 1593-600. PMID 16202982 DOI: 10.1016/J.Bcp.2005.08.014  0.585
2005 Duryee MJ, Freeman TL, Willis MS, Hunter CD, Hamilton BC, Suzuki H, Tuma DJ, Klassen LW, Thiele GM. Scavenger receptors on sinusoidal liver endothelial cells are involved in the uptake of aldehyde-modified proteins. Molecular Pharmacology. 68: 1423-30. PMID 16105988 DOI: 10.1124/Mol.105.016121  0.564
2005 Freeman TL, Tuma DJ, Thiele GM, Klassen LW, Worrall S, Niemelä O, Parkkila S, Emery PW, Preedy VR. Recent advances in alcohol-induced adduct formation. Alcoholism, Clinical and Experimental Research. 29: 1310-6. PMID 16088993 DOI: 10.1097/01.Alc.0000171484.52201.52  0.306
2005 Thiele GM, Hill GE, Pavlik JA, Freeman TL, Tuma DJ, Duryee MJ, Klassen LW. Halothane potentiates the alcohol-adduct induced TNF-alpha release in heart endothelial cells. Bmc Anesthesiology. 5: 3. PMID 15826301 DOI: 10.1186/1471-2253-5-3  0.368
2005 Zima T, Albano E, Ingelman-Sundberg M, Arteel GE, Thiele GM, Klassen LW, Sun AY. Modulation of Oxidative Stress by Alcohol Alcoholism: Clinical and Experimental Research. 29: 1060-1065. DOI: 10.1097/01.Alc.0000168168.43419.54  0.339
2004 Duryee MJ, Klassen LW, Freeman TL, Willis MS, Tuma DJ, Thiele GM. Lipopolysaccharide is a cofactor for malondialdehyde-acetaldehyde adduct-mediated cytokine/chemokine release by rat sinusoidal liver endothelial and Kupffer cells. Alcoholism, Clinical and Experimental Research. 28: 1931-8. PMID 15608611 DOI: 10.1097/01.Alc.0000148115.90045.C5  0.59
2004 Duryee MJ, Willis MS, Freeman TL, Kuszynski CA, Tuma DJ, Klassen LW, Thiele GM. Mechanisms of alcohol liver damage: aldehydes, scavenger receptors, and autoimmunity. Frontiers in Bioscience : a Journal and Virtual Library. 9: 3145-55. PMID 15353344 DOI: 10.2741/1467  0.599
2004 Thiele GM, Freeman TL, Klassen LW. Immunologic mechanisms of alcoholic liver injury. Seminars in Liver Disease. 24: 273-87. PMID 15349805 DOI: 10.1055/S-2004-832940  0.402
2004 Freeman TL, Thiele GM, Klassen LW, Klassen BT, Mailliard ME. N-(methylamino)isobutyric acid inhibits proliferation of CFSC-2C hepatic stellate cells. Biochemical Pharmacology. 68: 223-30. PMID 15193994 DOI: 10.1016/J.Bcp.2004.03.012  0.34
2004 Willis MS, Klassen LW, Carlson DL, Brouse CF, Thiele GM. Malondialdehyde-acetaldehyde haptenated protein binds macrophage scavenger receptor(s) and induces lysosomal damage. International Immunopharmacology. 4: 885-99. PMID 15182728 DOI: 10.1016/J.Intimp.2004.04.004  0.585
2004 Thiele GM, Duryee MJ, Willis MS, Sorrell MF, Freeman TL, Tuma DJ, Klassen LW. Malondialdehyde-acetaldehyde (MAA) modified proteins induce pro-inflammatory and pro-fibrotic responses by liver endothelial cells. Comparative Hepatology. 3: S25. PMID 14960177 DOI: 10.1186/1476-5926-2-S1-S25  0.606
2004 Klassen LW, Freeman TL, Duryee MJ, Willis MS, Tuma DJ, Thiele GM. MALONDIALDEHYDE-ACETALDEHYDE ADDUCTS: THE 2004 UPDATE. Alcoholism: Clinical & Experimental Research. 28: 67A. DOI: 10.1097/00000374-200408002-00364  0.48
2004 Thiele GM, Freeman TL, Duryee MJ, Willis MS, Tuma DJ, Klassen LW. SINUSOIDAL ENDOTHELIAL CELLS AND KUPFFER CELLS RESPOND TO PROTEINS MODIFIED BY ALDEHYDES PRODUCED UNDER OXIDATIVE STRESS. Alcoholism: Clinical & Experimental Research. 28: 55A. DOI: 10.1097/00000374-200408002-00288  0.517
2003 Duryee MJ, Klassen LW, Freeman TL, Willis MS, Tuma DJ, Thiele GM. Chronic ethanol consumption impairs receptor-mediated endocytosis of MAA-modified albumin by liver endothelial cells. Biochemical Pharmacology. 66: 1045-54. PMID 12963492 DOI: 10.1016/S0006-2952(03)00416-7  0.567
2003 Willis MS, Thiele GM, Tuma DJ, Klassen LW. T cell proliferative responses to malondialdehyde-acetaldehyde haptenated protein are scavenger receptor mediated. International Immunopharmacology. 3: 1381-99. PMID 12946435 DOI: 10.1016/S1567-5769(03)00136-X  0.575
2003 THIELE G, FREEMAN T, DURYEE M, WILLIS M, TUMA D, KLASSEN L. 1019 Lipopolysaccharide as a co-factor for malondialdehyde-acetaldehyde (MAA) modified proteins to induce pro-inflammatory responses by Kupffer and liver endothelial cells Hepatology. 38: 647-647. DOI: 10.1016/S0270-9139(03)81057-1  0.574
2003 THIELE G, FREEMAN T, WILLIS M, HUNTER C, TUMA D, KLASSEN L. 679 Identification of liver cytosolic proteins associated with malondialdehyde-acetaldehyde (MAA) adducted liver cytosol induced autoimmune hepatitis Hepatology. 38: 488-488. DOI: 10.1016/S0270-9139(03)80721-8  0.549
2002 Thiele GM, Szabo G, Kovacs EJ, Bautista AP, Sosa L, Jerrells TR. Modulation of immunity and viral-host interactions by alcohol. Alcoholism, Clinical and Experimental Research. 26: 1897-908. PMID 12500115 DOI: 10.1111/J.1530-0277.2002.Tb02498.X  0.342
2002 Willis MS, Klassen LW, Tuma DJ, Sorrell MF, Thiele GM. In vitro exposure to malondialdehyde-acetaldehyde adducted protein inhibits cell proliferation and viability. Alcoholism, Clinical and Experimental Research. 26: 158-64. PMID 11964554 DOI: 10.1111/J.1530-0277.2002.Tb02520.X  0.613
2002 Willis MS, Klassen LW, Tuma DJ, Thiele GM. Malondialdehyde-acetaldehyde-haptenated protein induces cell death by induction of necrosis and apoptosis in immune cells. International Immunopharmacology. 2: 519-35. PMID 11962731 DOI: 10.1016/S1567-5769(01)00195-3  0.583
2002 Willis MS, Klassen LW, Tuma DJ, Sorrell MF, Thiele GM. Adduction of soluble proteins with malondialdehyde-acetaldehyde (MAA) induces antibody production and enhances T-cell proliferation. Alcoholism, Clinical and Experimental Research. 26: 94-106. PMID 11821659 DOI: 10.1111/J.1530-0277.2002.Tb02436.X  0.587
2001 Tuma DJ, Kearley ML, Thiele GM, Worrall S, Haver A, Klassen LW, Sorrell MF. Elucidation of reaction scheme describing malondialdehyde-acetaldehyde-protein adduct formation. Chemical Research in Toxicology. 14: 822-832. PMID 11453728 DOI: 10.1021/Tx000222A  0.301
2001 Thiele GM, Worrall S, Tuma DJ, Klassen LW, Wyatt TA, Nagata N. The chemistry and biological effects of malondialdehyde-acetaldehyde adducts. Alcoholism: Clinical and Experimental Research. 25. DOI: 10.1111/J.1530-0277.2001.Tb02399.X  0.406
2000 Rolla R, Vay D, Mottaran E, Parodi M, Traverso N, Aricó S, Sartori M, Bellomo G, Klassen LW, Thiele GM, Tuma DJ, Albano E. Detection of circulating antibodies against malondialdehyde‐acetaldehyde adducts in patients with alcohol‐induced liver disease Hepatology. 31: 878-884. PMID 10733543 DOI: 10.1053/He.2000.5373  0.414
1999 Thiele GM, Miller JA, Klassen LW, Tuma DJ. Chronic ethanol consumption impairs receptor-mediated endocytosis of formaldehyde-treated albumin by isolated rat liver endothelial cells. Hepatology (Baltimore, Md.). 29: 1511-7. PMID 10216136 DOI: 10.1002/Hep.510290517  0.33
1999 Klassen LW, Jones BL, Sorrell MF, Tuma DJ, Thiele GM. Conversion of acetaldehyde-protein adduct epitopes from a nonreduced to a reduced phenotype by antigen processing cells. Alcoholism: Clinical and Experimental Research. 23: 657-663. DOI: 10.1111/J.1530-0277.1999.Tb04167.X  0.364
1998 Hill GE, Miller JA, Baxter BT, Klassen LW, Duryee MJ, Tuma DJ, Thiele GM. Association of malondialdehyde-acetaldehyde (MAA) adducted proteins with atherosclerotic-induced vascular inflammatory injury. Atherosclerosis. 141: 107-16. PMID 9863543 DOI: 10.1016/S0021-9150(98)00153-1  0.357
1998 Thiele GM, Tuma DJ, Miller JA, Wegter KM, McDonald TL, Klassen LW. Monoclonal and polyclonal antibodies recognizing acetaldehyde-protein adducts. Biochemical Pharmacology. 56: 1515-23. PMID 9827586 DOI: 10.1016/S0006-2952(98)00251-2  0.37
1998 Klassen LW, Thiele GM. Immune reactivity to proteins biotransformed by alcohol metabolites. Alcoholism: Clinical and Experimental Research. 22. PMID 9727636 DOI: 10.1111/J.1530-0277.1998.Tb04002.X  0.315
1998 Xu D, Thiele GM, Beckenhauer JL, Klassen LW, Sorrell MF, Tuma DJ. Detection of circulating antibodies to malondialdehyde-acetaldehyde adducts in ethanol-fed rats. Gastroenterology. 115: 686-92. PMID 9721166 DOI: 10.1016/S0016-5085(98)70148-9  0.347
1998 Thiele GM, Tuma DJ, Willis MS, Miller JA, McDonald TL, Sorrell MF, Klassen LW. Soluble Proteins Modified with Acetaldehyde and Malondialdehyde Are Immunogenic in the Absence of Adjuvant Alcoholism: Clinical and Experimental Research. 22: 1731-1739. DOI: 10.1111/J.1530-0277.1998.Tb03973.X  0.59
1997 Xu D, Thiele GM, Kearley ML, Haugen MD, Klassen LW, Sorrell MF, Tuma DJ. Epitope characterization of malondialdehyde-acetaldehyde adducts using an enzyme-linked immunosorbent assay. Chemical Research in Toxicology. 10: 978-986. PMID 9305579 DOI: 10.1021/Tx970069T  0.348
1996 Thiele GM, Miller JA, Klassen LW, Tuma DJ. Long-term ethanol administration alters the degradation of acetaldehyde adducts by liver endothelial cells. Hepatology (Baltimore, Md.). 24: 643-8. PMID 8781337 DOI: 10.1002/Hep.510240329  0.354
1996 Tuma DJ, Thiele GM, Xu D, Klassen LW, Sorrell MF. Acetaldehyde and malondialdehyde react together to generate distinct protein adducts in the liver during long-term ethanol administration Hepatology. 23: 872-880. DOI: 10.1053/Jhep.1996.V23.Pm0008666344  0.377
1995 Tempero MA, Haga Y, Sivinski C, Birt D, Klassen L, Thiele G. Immunologic Effects of Levamisole in Mice and Humans Journal of Immunotherapy. 17: 47-57. DOI: 10.1097/00002371-199501000-00006  0.317
1994 Klassen LW, Tuma DJ, Sorrell MF, McDonald TL, DeVasure JM, Thiele GM. Detection of Reduced Acetaldehyde Protein Adducts Using a Unique Monoclonal Antibody Alcoholism: Clinical and Experimental Research. 18: 164-171. PMID 8198215 DOI: 10.1111/J.1530-0277.1994.Tb00898.X  0.361
1994 Thiele GM, Wegter KM, Sorrell MF, Tuma DJ, McDonald TL, Klassen LW. Specificity to N-ethyl lysine of a monoclonal antibody to acetaldehyde-modified proteins prepared under reducing conditions Biochemical Pharmacology. 48: 183-189. PMID 8043021 DOI: 10.1016/0006-2952(94)90238-0  0.326
1992 Robbins RA, Koyama S, Spurzem JR, Rickard KA, Nelson KJ, Gossman GL, Thiele GM, Rennard SI. Modulation of neutrophil and mononuclear cell adherence to bronchial epithelial cells. American Journal of Respiratory Cell and Molecular Biology. 7: 19-29. PMID 1627334 DOI: 10.1165/Ajrcmb/7.1.19  0.307
1987 Thiele G, Bicak M, Grierson H, Lai P, David P. Antibody reactivity to a synthetic peptide (P62) of the Epstein-Barr nuclear antigen in sera of patients with X-linked lymphoproliferative syndrome Journal of Immunological Methods. 100: 249-259. PMID 3036951 DOI: 10.1016/0022-1759(87)90196-7  0.311
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