| Year |
Citation |
Score |
| 2023 |
Miao MZ, Su QP, Cui Y, Bahnson EM, Li G, Wang M, Yang Y, Collins JA, Wu D, Gu Q, Chubinskaya S, Diekman BO, Yamada KM, Loeser RF. Redox-active endosomes mediate α5β1 integrin signaling and promote chondrocyte matrix metalloproteinase production in osteoarthritis. Science Signaling. 16: eadf8299. PMID 37906629 DOI: 10.1126/scisignal.adf8299 |
0.367 |
|
| 2021 |
Willcockson H, Ozkan H, Chubinskaya S, Loeser RF, Longobardi L. CCL2 induces articular chondrocyte MMP expression through ERK and p38 signaling pathways. Osteoarthritis and Cartilage Open. 3: 100136. PMID 36475068 DOI: 10.1016/j.ocarto.2020.100136 |
0.342 |
|
| 2020 |
Copp ME, Flanders MC, Gagliardi R, Gilbertie JM, Sessions GA, Chubinskaya S, Loeser RF, Schnabel LV, Diekman BO. The combination of mitogenic stimulation and DNA damage induces chondrocyte senescence. Osteoarthritis and Cartilage. PMID 33227437 DOI: 10.1016/j.joca.2020.11.004 |
0.33 |
|
| 2020 |
Coryell PR, Diekman BO, Loeser RF. Mechanisms and therapeutic implications of cellular senescence in osteoarthritis. Nature Reviews. Rheumatology. PMID 33208917 DOI: 10.1038/s41584-020-00533-7 |
0.323 |
|
| 2020 |
Tessier S, Doolittle AC, Sao K, Rotty JD, Bear JE, Ulici V, Loeser RF, Shapiro IM, Diekman BO, Risbud MV. Arp2/3 inactivation causes intervertebral disc and cartilage degeneration with dysregulated TonEBP-mediated osmoadaptation. Jci Insight. PMID 31961823 DOI: 10.1172/Jci.Insight.131382 |
0.306 |
|
| 2018 |
Bolduc JA, Collins JA, Loeser RF. Reactive Oxygen Species, Aging and Articular Cartilage Homeostasis. Free Radical Biology & Medicine. PMID 30176344 DOI: 10.1016/j.freeradbiomed.2018.08.038 |
0.378 |
|
| 2017 |
Loeser RF. The Role of Aging in the Development of Osteoarthritis. Transactions of the American Clinical and Climatological Association. 128: 44-54. PMID 28790486 |
0.38 |
|
| 2017 |
Huang G, Chubinskaya S, Liao W, Loeser RF. Wnt5a Induces Catabolic Signaling and Matrix Metalloproteinase Production in Human Articular Chondrocytes. Osteoarthritis and Cartilage. PMID 28587781 DOI: 10.1016/J.Joca.2017.05.018 |
0.326 |
|
| 2016 |
Loeser RF, Collins JA, Diekman BO. Ageing and the pathogenesis of osteoarthritis. Nature Reviews. Rheumatology. PMID 27192932 DOI: 10.1038/Nrrheum.2016.65 |
0.313 |
|
| 2015 |
Wood ST, Long DL, Reisz JA, Yammani RR, Burke EA, Klomsiri C, Poole LB, Furdui CM, Loeser RF. Cysteine-Mediated Redox Regulation of Cell Signaling in Chondrocytes Stimulated with Fibronectin Fragments. Arthritis & Rheumatology (Hoboken, N.J.). PMID 26314228 DOI: 10.1002/Art.39326 |
0.309 |
|
| 2014 |
Loeser RF. Integrins and chondrocyte-matrix interactions in articular cartilage. Matrix Biology : Journal of the International Society For Matrix Biology. 39: 11-6. PMID 25169886 DOI: 10.1016/j.matbio.2014.08.007 |
0.347 |
|
| 2014 |
Stone AV, Loeser RF, Vanderman KS, Long DL, Clark SC, Ferguson CM. Pro-inflammatory stimulation of meniscus cells increases production of matrix metalloproteinases and additional catabolic factors involved in osteoarthritis pathogenesis. Osteoarthritis and Cartilage / Oars, Osteoarthritis Research Society. 22: 264-74. PMID 24315792 DOI: 10.1016/J.Joca.2013.11.002 |
0.315 |
|
| 2014 |
Vanderman K, Loeser R, Chubinskaya S, Ferguson C. Effects of osteoarthritis on meniscus cell response to osteogenic protein 1 Osteoarthritis and Cartilage. 22: S18. DOI: 10.1016/J.Joca.2014.02.055 |
0.3 |
|
| 2013 |
Long DL, Willey JS, Loeser RF. Rac1 is required for matrix metalloproteinase 13 production by chondrocytes in response to fibronectin fragments. Arthritis and Rheumatism. 65: 1561-8. PMID 23460186 DOI: 10.1002/Art.37922 |
0.31 |
|
| 2012 |
Loeser RF, Olex AL, McNulty MA, Carlson CS, Callahan MF, Ferguson CM, Chou J, Leng X, Fetrow JS. Microarray analysis reveals age-related differences in gene expression during the development of osteoarthritis in mice. Arthritis and Rheumatism. 64: 705-17. PMID 21972019 DOI: 10.1186/Gb-2010-11-S1-P29 |
0.339 |
|
| 2010 |
Miranda KJ, Loeser RF, Yammani RR. Sumoylation and nuclear translocation of S100A4 regulate IL-1beta-mediated production of matrix metalloproteinase-13. The Journal of Biological Chemistry. 285: 31517-24. PMID 20685652 DOI: 10.1074/jbc.M110.125898 |
0.305 |
|
| 2009 |
Yammani RR, Long D, Loeser RF. Interleukin-7 stimulates secretion of S100A4 by activating the JAK/STAT signaling pathway in human articular chondrocytes. Arthritis and Rheumatism. 60: 792-800. PMID 19248116 DOI: 10.1002/art.24295 |
0.329 |
|
| 2009 |
Cravero JD, Carlson CS, Im HJ, Yammani RR, Long D, Loeser RF. Increased expression of the Akt/PKB inhibitor TRB3 in osteoarthritic chondrocytes inhibits insulin-like growth factor 1-mediated cell survival and proteoglycan synthesis. Arthritis and Rheumatism. 60: 492-500. PMID 19180501 DOI: 10.1002/Art.24225 |
0.35 |
|
| 2009 |
McNulty M, Loeser R, Carlson C. 212 DEATH OF CHONDROCYTES IN MURINE ARTICULAR CARTILAGE: EFFECT OF AGE Osteoarthritis and Cartilage. 17: S120-S121. DOI: 10.1016/S1063-4584(09)60234-X |
0.301 |
|
| 2008 |
Del Carlo M, Loeser RF. Cell death in osteoarthritis. Current Rheumatology Reports. 10: 37-42. PMID 18457610 |
0.695 |
|
| 2008 |
Long D, Blake S, Song XY, Lark M, Loeser RF. Human articular chondrocytes produce IL-7 and respond to IL-7 with increased production of matrix metalloproteinase-13. Arthritis Research & Therapy. 10: R23. PMID 18289383 DOI: 10.1186/ar2376 |
0.322 |
|
| 2007 |
Del Carlo M, Schwartz D, Erickson EA, Loeser RF. Endogenous production of reactive oxygen species is required for stimulation of human articular chondrocyte matrix metalloproteinase production by fibronectin fragments. Free Radical Biology & Medicine. 42: 1350-8. PMID 17395008 DOI: 10.1016/j.freeradbiomed.2007.01.035 |
0.683 |
|
| 2007 |
Im HJ, Muddasani P, Natarajan V, Schmid TM, Block JA, Davis F, van Wijnen AJ, Loeser RF. Basic fibroblast growth factor stimulates matrix metalloproteinase-13 via the molecular cross-talk between the mitogen-activated protein kinases and protein kinase Cdelta pathways in human adult articular chondrocytes. The Journal of Biological Chemistry. 282: 11110-21. PMID 17311929 DOI: 10.1074/jbc.M609040200 |
0.325 |
|
| 2007 |
Byers-Kraus V, Cicconetti G, Jordan J, Renner J, Doherty M, Wilson A, Moskowitz R, Hochberg M, Loeser R, Atif U. 231 SYMMETRY OF RADIOGRAPHIC KNEE OSTEOARTHRITIS PROGRESSION IN SIBLING PAIRS WITH HAND OSTEOARTHRITIS Osteoarthritis and Cartilage. 15: C131. DOI: 10.1016/S1063-4584(07)61863-9 |
0.331 |
|
| 2006 |
Yammani RR, Carlson CS, Bresnick AR, Loeser RF. Increase in production of matrix metalloproteinase 13 by human articular chondrocytes due to stimulation with S100A4: Role of the receptor for advanced glycation end products. Arthritis and Rheumatism. 54: 2901-11. PMID 16948116 DOI: 10.1002/Art.22042 |
0.358 |
|
| 2006 |
DelCarlo M, Loeser RF. Chondrocyte cell death mediated by reactive oxygen species-dependent activation of PKC-betaI. American Journal of Physiology. Cell Physiology. 290: C802-11. PMID 16236825 DOI: 10.1152/ajpcell.00214.2005 |
0.364 |
|
| 2006 |
Atif U, Cicconetti G, Kraus V, Jordan JM, Renner JB, Stabler T, Huebner J, Doherty M, Wilson G, Moskowitz R, Hockberg M, Loeser R. P80 Joint Tissue Biomarker Analysis In Patients With Mild To Moderate Knee Osteoarthritis, From The Genetics Of Generalized Osteoarthritis (Gogo) Study Osteoarthritis and Cartilage. 14. DOI: 10.1016/S1063-4584(07)60532-9 |
0.309 |
|
| 2005 |
Forsyth CB, Cole A, Murphy G, Bienias JL, Im HJ, Loeser RF. Increased matrix metalloproteinase-13 production with aging by human articular chondrocytes in response to catabolic stimuli. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 60: 1118-24. PMID 16183949 DOI: 10.1093/Gerona/60.9.1118 |
0.329 |
|
| 2005 |
Loeser RF, Yammani RR, Carlson CS, Chen H, Cole A, Im HJ, Bursch LS, Yan SD. Articular chondrocytes express the receptor for advanced glycation end products: Potential role in osteoarthritis. Arthritis and Rheumatism. 52: 2376-85. PMID 16052547 DOI: 10.1002/Art.21199 |
0.34 |
|
| 2004 |
Kraus VB, Li YJ, Martin ER, Jordan JM, Renner JB, Doherty M, Wilson AG, Moskowitz R, Hochberg M, Loeser R, Hooper M, Sundseth S. Articular hypermobility is a protective factor for hand osteoarthritis. Arthritis and Rheumatism. 50: 2178-83. PMID 15248215 DOI: 10.1002/Art.20354 |
0.344 |
|
| 2003 |
Loeser RF, Pacione CA, Chubinskaya S. The combination of insulin-like growth factor 1 and osteogenic protein 1 promotes increased survival of and matrix synthesis by normal and osteoarthritic human articular chondrocytes. Arthritis and Rheumatism. 48: 2188-96. PMID 12905472 DOI: 10.1002/Art.11209 |
0.303 |
|
| 2002 |
Forsyth CB, Pulai J, Loeser RF. Fibronectin fragments and blocking antibodies to alpha2beta1 and alpha5beta1 integrins stimulate mitogen-activated protein kinase signaling and increase collagenase 3 (matrix metalloproteinase 13) production by human articular chondrocytes. Arthritis and Rheumatism. 46: 2368-76. PMID 12355484 DOI: 10.1002/art.10502 |
0.301 |
|
| 2002 |
Loeser RF, Carlson CS, Del Carlo M, Cole A. Detection of nitrotyrosine in aging and osteoarthritic cartilage: Correlation of oxidative damage with the presence of interleukin-1beta and with chondrocyte resistance to insulin-like growth factor 1. Arthritis and Rheumatism. 46: 2349-57. PMID 12355482 DOI: 10.1002/Art.10496 |
0.675 |
|
| 2002 |
Pulai JI, Del Carlo M, Loeser RF. The alpha5beta1 integrin provides matrix survival signals for normal and osteoarthritic human articular chondrocytes in vitro. Arthritis and Rheumatism. 46: 1528-35. PMID 12115183 DOI: 10.1002/art.10334 |
0.683 |
|
| 2002 |
Del Carlo M, Loeser RF. Nitric oxide-mediated chondrocyte cell death requires the generation of additional reactive oxygen species. Arthritis and Rheumatism. 46: 394-403. PMID 11840442 DOI: 10.1002/art.10056 |
0.693 |
|
| 1992 |
Loeser R, Carlson CS, Tulli H, Jerome WG, Miller L, Wallin R. Articular-cartilage matrix γ-carboxyglutamic acid-containing protein. Characterization and immunolocalization Biochemical Journal. 282: 1-6. PMID 1540125 DOI: 10.1042/Bj2820001 |
0.413 |
|
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