| Year |
Citation |
Score |
| 2020 |
Ji AL, Rubin AJ, Thrane K, Jiang S, Reynolds DL, Meyers RM, Guo MG, George BM, Mollbrink A, Bergenstråhle J, Larsson L, Bai Y, Zhu B, Bhaduri A, Meyers JM, ... ... Khavari PA, et al. Multimodal Analysis of Composition and Spatial Architecture in Human Squamous Cell Carcinoma. Cell. PMID 32579974 DOI: 10.1016/J.Cell.2020.05.039 |
0.346 |
|
| 2020 |
Carter AC, Xu J, Nakamoto MY, Wei Y, Zarnegar BJ, Shi Q, Broughton JP, Ransom RC, Salhotra A, Nagaraja SD, Li R, Dou DR, Yost KE, Cho SW, Mistry A, ... ... Khavari PA, et al. Spen links RNA-mediated endogenous retrovirus silencing and X chromosome inactivation. Elife. 9. PMID 32379046 DOI: 10.7554/Elife.54508 |
0.305 |
|
| 2019 |
Che Y, Siprashvili Z, Kovalski JR, Jiang T, Wozniak G, Elcavage L, Khavari PA. KRAS regulation by small non-coding RNAs and SNARE proteins. Nature Communications. 10: 5118. PMID 31712554 DOI: 10.1038/S41467-019-13106-4 |
0.32 |
|
| 2019 |
Yang X, Bayat V, DiDonato N, Zhao Y, Zarnegar B, Siprashvili Z, Lopez-Pajares V, Sun T, Tao S, Li C, Rump A, Khavari P, Lu B. Genetic and genomic studies of pathogenic EXOSC2 mutations in the newly described disease SHRF implicate the autophagy pathway in disease pathogenesis. Human Molecular Genetics. PMID 31628467 DOI: 10.1093/Hmg/Ddz251 |
0.357 |
|
| 2019 |
Ren L, Ding S, Song Y, Li B, Ramanathan M, Co J, Amieva MR, Khavari PA, Greenberg HB. Profiling of rotavirus 3'UTR-binding proteins reveals the ATP synthase subunit ATP5B as a host factor that supports late-stage virus replication. The Journal of Biological Chemistry. PMID 30770472 DOI: 10.1074/Jbc.Ra118.006004 |
0.302 |
|
| 2018 |
Rubin AJ, Parker KR, Satpathy AT, Qi Y, Wu B, Ong AJ, Mumbach MR, Ji AL, Kim DS, Cho SW, Zarnegar BJ, Greenleaf WJ, Chang HY, Khavari PA. Coupled Single-Cell CRISPR Screening and Epigenomic Profiling Reveals Causal Gene Regulatory Networks. Cell. PMID 30580963 DOI: 10.1016/J.Cell.2018.11.022 |
0.362 |
|
| 2018 |
Pattison JM, Melo SP, Piekos SN, Torkelson JL, Bashkirova E, Mumbach MR, Rajasingh C, Zhen HH, Li L, Liaw E, Alber D, Rubin AJ, Shankar G, Bao X, Chang HY, ... Khavari PA, et al. Retinoic acid and BMP4 cooperate with p63 to alter chromatin dynamics during surface epithelial commitment. Nature Genetics. PMID 30397335 DOI: 10.1038/S41588-018-0263-0 |
0.333 |
|
| 2018 |
Ramanathan M, Majzoub K, Rao DS, Neela PH, Zarnegar BJ, Mondal S, Roth JG, Gai H, Kovalski JR, Siprashvili Z, Palmer TD, Carette JE, Khavari PA. RNA-protein interaction detection in living cells. Nature Methods. PMID 29400715 DOI: 10.1038/Nmeth.4601 |
0.31 |
|
| 2017 |
Ransohoff JD, Wei Y, Khavari PA. The functions and unique features of long intergenic non-coding RNA. Nature Reviews. Molecular Cell Biology. PMID 29138516 DOI: 10.1038/Nrm.2017.104 |
0.307 |
|
| 2017 |
Mumbach MR, Satpathy AT, Boyle EA, Dai C, Gowen BG, Cho SW, Nguyen ML, Rubin AJ, Granja JM, Kazane KR, Wei Y, Nguyen T, Greenside PG, Corces MR, Tycko J, ... ... Khavari PA, et al. Enhancer connectome in primary human cells identifies target genes of disease-associated DNA elements. Nature Genetics. PMID 28945252 DOI: 10.1038/Ng.3963 |
0.353 |
|
| 2017 |
Bao X, Siprashvili Z, Zarnegar BJ, Shenoy RM, Rios EJ, Nady N, Qu K, Mah A, Webster DE, Rubin AJ, Wozniak GG, Tao S, Wysocka J, Khavari PA. CSNK1a1 Regulates PRMT1 to Maintain the Progenitor State in Self-Renewing Somatic Tissue. Developmental Cell. PMID 28943242 DOI: 10.1016/J.Devcel.2017.08.021 |
0.358 |
|
| 2017 |
Rubin AJ, Barajas BC, Furlan-Magaril M, Lopez-Pajares V, Mumbach MR, Howard I, Kim DS, Boxer LD, Cairns J, Spivakov M, Wingett SW, Shi M, Zhao Z, Greenleaf WJ, Kundaje A, ... ... Khavari PA, et al. Lineage-specific dynamic and pre-established enhancer-promoter contacts cooperate in terminal differentiation. Nature Genetics. PMID 28805829 DOI: 10.1038/Ng.3935 |
0.361 |
|
| 2017 |
Gong X, Siprashvili Z, Eminaga O, Shen Z, Sato Y, Kume H, Homma Y, Ogawa S, Khavari PA, Pollack JR, Brooks JD. Novel lincRNA SLINKY is a prognostic biomarker in kidney cancer. Oncotarget. 8: 18657-18669. PMID 28423633 DOI: 10.18632/Oncotarget.15703 |
0.318 |
|
| 2017 |
Ransohoff J, Ramanathan M, Khavari P. 408 Discovery of differential RNA binding and regulation by the APOL4 protein to disease-linked psoriasis CDSN gene variants using RaPID Journal of Investigative Dermatology. 137: S71. DOI: 10.1016/J.Jid.2017.02.427 |
0.334 |
|
| 2017 |
Ramanathan M, Majzoub K, Roth J, Gai H, Palmer T, Carette J, Khavari P. 123 RNA-protein interaction detection (RaPID) in living cells uncovers post-transcriptional regulation in carcinogenesis Journal of Investigative Dermatology. 137: S21. DOI: 10.1016/J.Jid.2017.02.137 |
0.335 |
|
| 2016 |
Winge MC, Ohyama B, Dey CN, Boxer LM, Li W, Ehsani-Chimeh N, Truong AK, Wu D, Armstrong AW, Makino T, Davidson M, Starcevic D, Kislat A, Nguyen NT, Hashimoto T, ... ... Khavari PA, et al. RAC1 activation drives pathologic interactions between the epidermis and immune cells. The Journal of Clinical Investigation. PMID 27294528 DOI: 10.1172/Jci85738 |
0.377 |
|
| 2016 |
Flynn RA, Do BT, Rubin AJ, Calo E, Lee B, Kuchelmeister H, Rale M, Chu C, Kool ET, Wysocka J, Khavari PA, Chang HY. 7SK-BAF axis controls pervasive transcription at enhancers. Nature Structural & Molecular Biology. PMID 26878240 DOI: 10.1038/Nsmb.3176 |
0.341 |
|
| 2016 |
Lopez-Pajares V, Barajas B, Rubin A, Khavari P. 335 Regulation of epidermal differentiation by MAF and MAFB Journal of Investigative Dermatology. 136: S59. DOI: 10.1016/J.Jid.2016.02.367 |
0.301 |
|
| 2015 |
Bao X, Rubin AJ, Qu K, Zhang J, Giresi PG, Chang HY, Khavari PA. A novel ATAC-seq approach reveals lineage-specific reinforcement of the open chromatin landscape via cooperation between BAF and p63. Genome Biology. 16: 284. PMID 26683334 DOI: 10.1186/S13059-015-0840-9 |
0.315 |
|
| 2015 |
Bhaduri A, Ungewickell A, Boxer LD, Lopez-Pajares V, Zarnegar BJ, Khavari PA. Network Analysis Identifies Mitochondrial Regulation of Epidermal Differentiation by MPZL3 and FDXR. Developmental Cell. 35: 444-57. PMID 26609959 DOI: 10.1016/J.Devcel.2015.10.023 |
0.325 |
|
| 2015 |
Siprashvili Z, Webster DE, Johnston D, Shenoy RM, Ungewickell AJ, Bhaduri A, Flockhart R, Zarnegar BJ, Che Y, Meschi F, Puglisi JD, Khavari PA. The noncoding RNAs SNORD50A and SNORD50B bind K-Ras and are recurrently deleted in human cancer. Nature Genetics. PMID 26595770 DOI: 10.1038/Ng.3452 |
0.308 |
|
| 2015 |
Sun BK, Boxer LD, Ransohoff JD, Siprashvili Z, Qu K, Lopez-Pajares V, Hollmig ST, Khavari PA. CALML5 is a ZNF750- and TINCR-induced protein that binds stratifin to regulate epidermal differentiation. Genes & Development. 29: 2225-30. PMID 26545810 DOI: 10.1101/Gad.267708.115 |
0.364 |
|
| 2015 |
Ungewickell A, Bhaduri A, Rios E, Reuter J, Lee CS, Mah A, Zehnder A, Ohgami R, Kulkarni S, Armstrong R, Weng WK, Gratzinger D, Tavallaee M, Rook A, Snyder M, ... ... Khavari PA, et al. Genomic analysis of mycosis fungoides and Sézary syndrome identifies recurrent alterations in TNFR2. Nature Genetics. PMID 26258847 DOI: 10.1038/Ng.3370 |
0.33 |
|
| 2015 |
Lopez-Pajares V, Qu K, Zhang J, Webster DE, Barajas BC, Siprashvili Z, Zarnegar BJ, Boxer LD, Rios EJ, Tao S, Kretz M, Khavari PA. A LncRNA-MAF:MAFB transcription factor network regulates epidermal differentiation. Developmental Cell. 32: 693-706. PMID 25805135 DOI: 10.1016/J.Devcel.2015.01.028 |
0.36 |
|
| 2015 |
Zehnder A, Lee B, Neela P, Khavari P. Abstract 5137: IQGAP1, an ERK1/2 MAPK scaffold, is an oncogenic target in canine melanoma Cancer Research. 75: 5137-5137. DOI: 10.1158/1538-7445.Am2015-5137 |
0.385 |
|
| 2014 |
Sun BK, Siprashvili Z, Khavari PA. Advances in skin grafting and treatment of cutaneous wounds. Science (New York, N.Y.). 346: 941-5. PMID 25414301 DOI: 10.1126/Science.1253836 |
0.317 |
|
| 2014 |
Marques Howarth M, Simpson D, Ngok SP, Nieves B, Chen R, Siprashvili Z, Vaka D, Breese MR, Crompton BD, Alexe G, Hawkins DS, Jacobson D, Brunner AL, West R, Mora J, ... ... Khavari P, et al. Long noncoding RNA EWSAT1-mediated gene repression facilitates Ewing sarcoma oncogenesis. The Journal of Clinical Investigation. 124: 5275-90. PMID 25401475 DOI: 10.1172/Jci72124 |
0.392 |
|
| 2014 |
Boxer LD, Barajas B, Tao S, Zhang J, Khavari PA. ZNF750 interacts with KLF4 and RCOR1, KDM1A, and CTBP1/2 chromatin regulators to repress epidermal progenitor genes and induce differentiation genes. Genes & Development. 28: 2013-26. PMID 25228645 DOI: 10.1101/Gad.246579.114 |
0.365 |
|
| 2014 |
Lee CS, Bhaduri A, Mah A, Johnson WL, Ungewickell A, Aros CJ, Nguyen CB, Rios EJ, Siprashvili Z, Straight A, Kim J, Aasi SZ, Khavari PA. Recurrent point mutations in the kinetochore gene KNSTRN in cutaneous squamous cell carcinoma. Nature Genetics. 46: 1060-2. PMID 25194279 DOI: 10.1038/Ng.3091 |
0.34 |
|
| 2014 |
Zheng GX, Do BT, Webster DE, Khavari PA, Chang HY. Dicer-microRNA-Myc circuit promotes transcription of hundreds of long noncoding RNAs. Nature Structural & Molecular Biology. 21: 585-90. PMID 24929436 DOI: 10.1038/Nsmb.2842 |
0.326 |
|
| 2014 |
Webster DE, Barajas B, Bussat RT, Yan KJ, Neela PH, Flockhart RJ, Kovalski J, Zehnder A, Khavari PA. Enhancer-targeted genome editing selectively blocks innate resistance to oncokinase inhibition. Genome Research. 24: 751-60. PMID 24443471 DOI: 10.1101/Gr.166231.113 |
0.351 |
|
| 2014 |
Gocke CB, Wang Q, McMillan R, Penchev V, Sage J, Khavari PA, Matsui W. Inhibiting Oncogenic RAS in Multiple Myeloma By Targeting Scaffold-ERK Interactions Blood. 124: 2089-2089. DOI: 10.1182/Blood.V124.21.2089.2089 |
0.324 |
|
| 2013 |
Sarin KY, Sun BK, Bangs CD, Cherry A, Swetter SM, Kim J, Khavari PA. Activating HRAS mutation in agminated Spitz nevi arising in a nevus spilus. Jama Dermatology. 149: 1077-81. PMID 23884457 DOI: 10.1001/Jamadermatol.2013.4745 |
0.317 |
|
| 2013 |
Jameson KL, Mazur PK, Zehnder AM, Zhang J, Zarnegar B, Sage J, Khavari PA. IQGAP1 scaffold-kinase interaction blockade selectively targets RAS-MAP kinase-driven tumors. Nature Medicine. 19: 626-30. PMID 23603816 DOI: 10.1038/Nm.3165 |
0.324 |
|
| 2013 |
Bao X, Tang J, Lopez-Pajares V, Tao S, Qu K, Crabtree GR, Khavari PA. ACTL6a enforces the epidermal progenitor state by suppressing SWI/SNF-dependent induction of KLF4. Cell Stem Cell. 12: 193-203. PMID 23395444 DOI: 10.1016/J.Stem.2012.12.014 |
0.54 |
|
| 2013 |
Kretz M, Siprashvili Z, Chu C, Webster DE, Zehnder A, Qu K, Lee CS, Flockhart RJ, Groff AF, Chow J, Johnston D, Kim GE, Spitale RC, Flynn RA, Zheng GX, ... ... Khavari PA, et al. Control of somatic tissue differentiation by the long non-coding RNA TINCR. Nature. 493: 231-5. PMID 23201690 DOI: 10.1038/Nature11661 |
0.343 |
|
| 2013 |
Lopez-Pajares V, Yan K, Zarnegar BJ, Jameson KL, Khavari PA. Genetic pathways in disorders of epidermal differentiation. Trends in Genetics : Tig. 29: 31-40. PMID 23141808 DOI: 10.1016/J.Tig.2012.10.005 |
0.353 |
|
| 2013 |
Sun BK, Saggini A, Sarin KY, Kim J, Benjamin L, LeBoit PE, Khavari PA. Mosaic activating RAS mutations in nevus sebaceus and nevus sebaceus syndrome. The Journal of Investigative Dermatology. 133: 824-7. PMID 23096709 DOI: 10.1038/Jid.2012.377 |
0.319 |
|
| 2012 |
Lee CS, Ungewickell A, Bhaduri A, Qu K, Webster DE, Armstrong R, Weng WK, Aros CJ, Mah A, Chen RO, Lin M, Sundram U, Chang HY, Kretz M, Kim YH, ... Khavari PA, et al. Transcriptome sequencing in Sezary syndrome identifies Sezary cell and mycosis fungoides-associated lncRNAs and novel transcripts. Blood. 120: 3288-97. PMID 22936659 DOI: 10.1182/Blood-2012-04-423061 |
0.404 |
|
| 2012 |
Zarnegar BJ, Webster DE, Lopez-Pajares V, Vander Stoep Hunt B, Qu K, Yan KJ, Berk DR, Sen GL, Khavari PA. Genomic profiling of a human organotypic model of AEC syndrome reveals ZNF750 as an essential downstream target of mutant TP63. American Journal of Human Genetics. 91: 435-43. PMID 22922031 DOI: 10.1016/J.Ajhg.2012.07.007 |
0.346 |
|
| 2012 |
Sen GL, Boxer LD, Webster DE, Bussat RT, Qu K, Zarnegar BJ, Johnston D, Siprashvili Z, Khavari PA. ZNF750 is a p63 target gene that induces KLF4 to drive terminal epidermal differentiation. Developmental Cell. 22: 669-77. PMID 22364861 DOI: 10.1016/J.Devcel.2011.12.001 |
0.385 |
|
| 2012 |
Kretz M, Webster DE, Flockhart RJ, Lee CS, Zehnder A, Lopez-Pajares V, Qu K, Zheng GX, Chow J, Kim GE, Rinn JL, Chang HY, Siprashvili Z, Khavari PA. Suppression of progenitor differentiation requires the long noncoding RNA ANCR. Genes & Development. 26: 338-43. PMID 22302877 DOI: 10.1101/Gad.182121.111 |
0.351 |
|
| 2010 |
Ridky TW, Chow JM, Wong DJ, Khavari PA. Invasive three-dimensional organotypic neoplasia from multiple normal human epithelia. Nature Medicine. 16: 1450-5. PMID 21102459 DOI: 10.1038/Nm.2265 |
0.329 |
|
| 2010 |
Siprashvili Z, Nguyen NT, Bezchinsky MY, Marinkovich MP, Lane AT, Khavari PA. Long-term type VII collagen restoration to human epidermolysis bullosa skin tissue. Human Gene Therapy. 21: 1299-310. PMID 20497034 DOI: 10.1089/Hum.2010.023 |
0.327 |
|
| 2010 |
Ridky TW, Khavari PA. The hair follicle bulge stem cell niche resists transformation by the hedgehog pathway. Cell Stem Cell. 6: 292-4. PMID 20362530 DOI: 10.1016/J.Stem.2010.03.009 |
0.321 |
|
| 2010 |
Sen GL, Reuter JA, Webster DE, Zhu L, Khavari PA. DNMT1 maintains progenitor function in self-renewing somatic tissue. Nature. 463: 563-7. PMID 20081831 DOI: 10.1038/Nature08683 |
0.326 |
|
| 2009 |
Reuter JA, Ortiz-Urda S, Kretz M, Garcia J, Scholl FA, Pasmooij AM, Cassarino D, Chang HY, Khavari PA. Modeling inducible human tissue neoplasia identifies an extracellular matrix interaction network involved in cancer progression. Cancer Cell. 15: 477-88. PMID 19477427 DOI: 10.1016/J.Ccr.2009.04.002 |
0.324 |
|
| 2009 |
Dumesic PA, Scholl FA, Barragan DI, Khavari PA. Erk1/2 MAP kinases are required for epidermal G2/M progression. The Journal of Cell Biology. 185: 409-22. PMID 19414607 DOI: 10.1083/Jcb.200804038 |
0.366 |
|
| 2009 |
Scholl FA, Dumesic PA, Barragan DI, Harada K, Charron J, Khavari PA. Selective role for Mek1 but not Mek2 in the induction of epidermal neoplasia. Cancer Research. 69: 3772-8. PMID 19383924 DOI: 10.1158/0008-5472.Can-08-1963 |
0.352 |
|
| 2009 |
Scholl FA, Dumesic PA, Barragan DI, Charron J, Khavari PA. Mek1/2 gene dosage determines tissue response to oncogenic Ras signaling in the skin. Oncogene. 28: 1485-95. PMID 19198628 DOI: 10.1038/Onc.2008.459 |
0.341 |
|
| 2008 |
Sen GL, Webster DE, Barragan DI, Chang HY, Khavari PA. Control of differentiation in a self-renewing mammalian tissue by the histone demethylase JMJD3. Genes & Development. 22: 1865-70. PMID 18628393 DOI: 10.1101/Gad.1673508 |
0.348 |
|
| 2007 |
Waterman EA, Sakai N, Nguyen NT, Horst BA, Veitch DP, Dey CN, Ortiz-Urda S, Khavari PA, Marinkovich MP. A laminin-collagen complex drives human epidermal carcinogenesis through phosphoinositol-3-kinase activation. Cancer Research. 67: 4264-70. PMID 17483338 DOI: 10.1158/0008-5472.Can-06-4141 |
0.334 |
|
| 2007 |
Zhang JY, Adams AE, Ridky TW, Tao S, Khavari PA. Tumor necrosis factor receptor 1/c-Jun-NH2-kinase signaling promotes human neoplasia. Cancer Research. 67: 3827-34. PMID 17440097 DOI: 10.1158/0008-5472.Can-06-4017 |
0.366 |
|
| 2007 |
Scholl FA, Dumesic PA, Barragan DI, Harada K, Bissonauth V, Charron J, Khavari PA. Mek1/2 MAPK kinases are essential for Mammalian development, homeostasis, and Raf-induced hyperplasia. Developmental Cell. 12: 615-29. PMID 17419998 DOI: 10.1016/J.Devcel.2007.03.009 |
0.371 |
|
| 2007 |
Truong AB, Khavari PA. Control of keratinocyte proliferation and differentiation by p63. Cell Cycle (Georgetown, Tex.). 6: 295-9. PMID 17264679 DOI: 10.4161/Cc.6.3.3753 |
0.306 |
|
| 2006 |
Truong AB, Kretz M, Ridky TW, Kimmel R, Khavari PA. p63 regulates proliferation and differentiation of developmentally mature keratinocytes. Genes & Development. 20: 3185-97. PMID 17114587 DOI: 10.1101/Gad.1463206 |
0.316 |
|
| 2006 |
Reuter JA, Khavari PA. Use of conditionally active ras fusion proteins to study epidermal growth, differentiation, and neoplasia. Methods in Enzymology. 407: 691-702. PMID 16757362 DOI: 10.1016/S0076-6879(05)07054-0 |
0.309 |
|
| 2006 |
Adams AE, Chudnovsky Y, Khavari PA. Oxygen deprivation provokes melanoma. Nature Medicine. 12: 168-9. PMID 16462795 DOI: 10.1038/Nm0206-168 |
0.732 |
|
| 2005 |
Harada K, Truong AB, Cai T, Khavari PA. The class II phosphoinositide 3-kinase C2beta is not essential for epidermal differentiation. Molecular and Cellular Biology. 25: 11122-30. PMID 16314532 DOI: 10.1128/Mcb.25.24.11122-11130.2005 |
0.334 |
|
| 2005 |
Scholl FA, Dumesic PA, Khavari PA. Effects of active MEK1 expression in vivo. Cancer Letters. 230: 1-5. PMID 16253755 DOI: 10.1016/J.Canlet.2004.12.013 |
0.417 |
|
| 2005 |
Chudnovsky Y, Adams AE, Robbins PB, Lin Q, Khavari PA. Use of human tissue to assess the oncogenic activity of melanoma-associated mutations. Nature Genetics. 37: 745-9. PMID 15951821 DOI: 10.1038/Ng1586 |
0.756 |
|
| 2005 |
Chudnovsky Y, Khavari PA, Adams AE. Melanoma genetics and the development of rational therapeutics. The Journal of Clinical Investigation. 115: 813-24. PMID 15841168 DOI: 10.1172/Jci24808 |
0.744 |
|
| 2005 |
Ortiz-Urda S, Garcia J, Green CL, Chen L, Lin Q, Veitch DP, Sakai LY, Lee H, Marinkovich MP, Khavari PA. Type VII collagen is required for Ras-driven human epidermal tumorigenesis. Science (New York, N.Y.). 307: 1773-6. PMID 15774758 DOI: 10.1126/Science.1106209 |
0.355 |
|
| 2005 |
Zhang JY, Tao S, Kimmel R, Khavari PA. CDK4 regulation by TNFR1 and JNK is required for NF-kappaB-mediated epidermal growth control. The Journal of Cell Biology. 168: 561-6. PMID 15699216 DOI: 10.1083/Jcb.200411060 |
0.392 |
|
| 2004 |
Scholl FA, Dumesic PA, Khavari PA. Mek1 alters epidermal growth and differentiation. Cancer Research. 64: 6035-40. PMID 15342384 DOI: 10.1158/0008-5472.Can-04-0017 |
0.332 |
|
| 2004 |
Khavari PA. Profiling epithelial stem cells. Nature Biotechnology. 22: 393-4. PMID 15060550 DOI: 10.1038/Nbt0404-393 |
0.309 |
|
| 2004 |
Ridky TW, Khavari PA. Pathways sufficient to induce epidermal carcinogenesis. Cell Cycle (Georgetown, Tex.). 3: 621-4. PMID 15044848 DOI: 10.4161/Cc.3.5.860 |
0.408 |
|
| 2004 |
Green CL, Khavari PA. Targets for molecular therapy of skin cancer. Seminars in Cancer Biology. 14: 63-9. PMID 14757536 DOI: 10.1016/J.Semcancer.2003.11.007 |
0.383 |
|
| 2004 |
Siprashvili Z, Khavari PA. Lentivectors for regulated and reversible cutaneous gene delivery. Molecular Therapy : the Journal of the American Society of Gene Therapy. 9: 93-100. PMID 14741782 DOI: 10.1016/J.Ymthe.2003.09.016 |
0.365 |
|
| 2004 |
Zhang JY, Green CL, Tao S, Khavari PA. NF-kappaB RelA opposes epidermal proliferation driven by TNFR1 and JNK. Genes & Development. 18: 17-22. PMID 14724177 DOI: 10.1101/Gad.1160904 |
0.401 |
|
| 2003 |
Ortiz-Urda S, Thyagarajan B, Keene DR, Lin Q, Calos MP, Khavari PA. PhiC31 integrase-mediated nonviral genetic correction of junctional epidermolysis bullosa. Human Gene Therapy. 14: 923-8. PMID 12828862 DOI: 10.1089/104303403765701204 |
0.341 |
|
| 2003 |
Ortiz-Urda S, Lin Q, Yant SR, Keene D, Kay MA, Khavari PA. Sustainable correction of junctional epidermolysis bullosa via transposon-mediated nonviral gene transfer. Gene Therapy. 10: 1099-104. PMID 12808440 DOI: 10.1038/Sj.Gt.3301978 |
0.363 |
|
| 2003 |
Hinata K, Gervin AM, Jennifer Zhang Y, Khavari PA. Divergent gene regulation and growth effects by NF-kappa B in epithelial and mesenchymal cells of human skin. Oncogene. 22: 1955-64. PMID 12673201 DOI: 10.1038/Sj.Onc.1206198 |
0.758 |
|
| 2003 |
Dajee M, Lazarov M, Zhang JY, Cai T, Green CL, Russell AJ, Marinkovich MP, Tao S, Lin Q, Kubo Y, Khavari PA. NF-kappaB blockade and oncogenic Ras trigger invasive human epidermal neoplasia. Nature. 421: 639-43. PMID 12571598 DOI: 10.1038/Nature01283 |
0.408 |
|
| 2003 |
Ortiz-Urda S, Lin Q, Green CL, Keene DR, Marinkovich MP, Khavari PA. Injection of genetically engineered fibroblasts corrects regenerated human epidermolysis bullosa skin tissue. The Journal of Clinical Investigation. 111: 251-5. PMID 12531881 DOI: 10.1172/Jci17193 |
0.304 |
|
| 2002 |
Cai T, Nishida K, Hirano T, Khavari PA. Gab1 and SHP-2 promote Ras/MAPK regulation of epidermal growth and differentiation. The Journal of Cell Biology. 159: 103-12. PMID 12370245 DOI: 10.1083/Jcb.200205017 |
0.317 |
|
| 2002 |
Lazarov M, Kubo Y, Cai T, Dajee M, Tarutani M, Lin Q, Fang M, Tao S, Green CL, Khavari PA. CDK4 coexpression with Ras generates malignant human epidermal tumorigenesis. Nature Medicine. 8: 1105-14. PMID 12357246 DOI: 10.1038/Nm779 |
0.342 |
|
| 2002 |
Ortiz-Urda S, Thyagarajan B, Keene DR, Lin Q, Fang M, Calos MP, Khavari PA. Stable nonviral genetic correction of inherited human skin disease Nature Medicine. 8: 1166-1170. PMID 12244305 DOI: 10.1038/Nm766 |
0.342 |
|
| 2001 |
Baek SC, Lin Q, Robbins PB, Fan H, Khavari PA. Sustainable systemic delivery via a single injection of lentivirus into human skin tissue Human Gene Therapy. 12: 1551-1558. PMID 11506697 DOI: 10.1089/10430340152480276 |
0.343 |
|
| 2001 |
Robbins PB, Sheu SM, Goodnough JB, Khavari PA. Impact of laminin 5 β3 gene versus protein replacement on gene expression patterns in junctional epidermolysis bullosa Human Gene Therapy. 12: 1443-1448. PMID 11485635 DOI: 10.1089/104303401750298599 |
0.322 |
|
| 2001 |
Khavari PA. Genetic correction of inherited epidermal disorders. Human Gene Therapy. 11: 2277-82. PMID 11084686 DOI: 10.1089/104303400750035816 |
0.364 |
|
| 2000 |
Seitz CS, Deng H, Hinata K, Lin Q, Khavari PA. Nuclear factor kappaB subunits induce epithelial cell growth arrest. Cancer Research. 60: 4085-92. PMID 10945614 |
0.759 |
|
| 2000 |
Seitz CS, Freiberg RA, Hinata K, Khavari PA. NF-kappaB determines localization and features of cell death in epidermis. The Journal of Clinical Investigation. 105: 253-60. PMID 10675350 DOI: 10.1172/Jci7630 |
0.756 |
|
| 1999 |
Fan H, Khavari PA. Sonic hedgehog opposes epithelial cell cycle arrest. The Journal of Cell Biology. 147: 71-6. PMID 10508856 DOI: 10.1083/Jcb.147.1.71 |
0.366 |
|
| 1998 |
Deng H, Choate KA, Lin Q, Khavari PA. High-efficiency gene transfer and pharmacologic selection of genetically engineered human keratinocytes Biotechniques. 25: 274-280. PMID 9714888 DOI: 10.2144/98252Gt02 |
0.35 |
|
| 1998 |
Seitz CS, Lin Q, Deng H, Khavari PA. Alterations in NF-kappaB function in transgenic epithelial tissue demonstrate a growth inhibitory role for NF-kappaB. Proceedings of the National Academy of Sciences of the United States of America. 95: 2307-12. PMID 9482881 DOI: 10.1073/Pnas.95.5.2307 |
0.412 |
|
| 1998 |
Khavari PA. Therapeutic gene delivery to the skin. Molecular Medicine Today. 3: 533-8. PMID 9449124 DOI: 10.1016/S1357-4310(97)01143-X |
0.331 |
|
| 1998 |
Deng H, Lin Q, Khavari PA. Sustainable cutaneous gene delivery. Nature Biotechnology. 15: 1388-91. PMID 9415892 DOI: 10.1038/Nbt1297-1388 |
0.364 |
|
| 1998 |
Fan H, Khavari P. Sonic hedgehog regulates keratinocyte differentiation gene expression and cell cycle progression Journal of Dermatological Science. 16: S14. DOI: 10.1016/S0923-1811(98)83083-1 |
0.374 |
|
| 1997 |
Choate KA, Khavari PA. Direct cutaneous gene delivery in a human genetic skin disease. Human Gene Therapy. 8: 1659-65. PMID 9322868 DOI: 10.1089/Hum.1997.8.14-1659 |
0.353 |
|
| 1997 |
Fan H, Oro AE, Scott MP, Khavari PA. Induction of basal cell carcinoma features in transgenic human skin expressing Sonic Hedgehog. Nature Medicine. 3: 788-92. PMID 9212109 DOI: 10.1038/Nm0797-788 |
0.408 |
|
| 1997 |
Choate KA, Khavari PA. Sustainability of keratinocyte gene transfer and cell survival in vivo. Human Gene Therapy. 8: 895-901. PMID 9195211 DOI: 10.1089/Hum.1997.8.8-895 |
0.361 |
|
| 1997 |
Freiberg RA, Choate KA, Deng H, Alperin ES, Shapiro LJ, Khavari PA. A model of corrective gene transfer in X-linked ichthyosis. Human Molecular Genetics. 6: 927-33. PMID 9175741 DOI: 10.1093/Hmg/6.6.927 |
0.372 |
|
| 1997 |
Freiberg RA, Spencer DM, Choate KA, Duh HJ, Schreiber SL, Crabtree GR, Khavari PA. Fas signal transduction triggers either proliferation or apoptosis in human fibroblasts. The Journal of Investigative Dermatology. 108: 215-9. PMID 9008237 DOI: 10.1111/1523-1747.Ep12334273 |
0.516 |
|
| 1996 |
Choate KA, Kinsella TM, Williams ML, Nolan GP, Khavari PA. Transglutaminase 1 delivery to lamellar ichthyosis keratinocytes. Human Gene Therapy. 7: 2247-53. PMID 8953315 DOI: 10.1089/Hum.1996.7.18-2247 |
0.364 |
|
| 1996 |
Freiberg RA, Spencer DM, Choate KA, Peng PD, Schreiber SL, Crabtree GR, Khavari PA. Specific triggering of the Fas signal transduction pathway in normal human keratinocytes. The Journal of Biological Chemistry. 271: 31666-9. PMID 8940187 DOI: 10.1074/Jbc.271.49.31666 |
0.45 |
|
| 1996 |
Choate KA, Medalie DA, Morgan JR, Khavari PA. Corrective gene transfer in the human skin disorder lamellar ichthyosis Nature Medicine. 2: 1263-1267. PMID 8898758 DOI: 10.1038/Nm1196-1263 |
0.348 |
|
| 1996 |
Wang W, Côté J, Xue Y, Zhou S, Khavari PA, Biggar SR, Muchardt C, Kalpana GV, Goff SP, Yaniv M, Workman JL, Crabtree GR. Purification and biochemical heterogeneity of the mammalian SWI-SNF complex. The Embo Journal. 15: 5370-5382. DOI: 10.1002/J.1460-2075.1996.Tb00921.X |
0.734 |
|
| 1994 |
Kwon H, Imbalzano AN, Khavari PA, Kingston RE, Green MR. Nucleosome disruption and enhancement of activator binding by a human SW1/SNF complex Nature. 370: 477-481. PMID 8047169 DOI: 10.1038/370477A0 |
0.326 |
|
| 1994 |
Dunaief JL, Strober BE, Guha S, Khavari PA, Alin K, Luban J, Begemann M, Crabtree GR, Goff SP. The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest. Cell. 79: 119-30. PMID 7923370 DOI: 10.1016/0092-8674(94)90405-7 |
0.565 |
|
| 1994 |
Randazzo FM, Khavari P, Crabtree G, Tamkun J, Rossant J. brg1: a putative murine homologue of the Drosophila brahma gene, a homeotic gene regulator. Developmental Biology. 161: 229-42. PMID 7904967 DOI: 10.1006/Dbio.1994.1023 |
0.517 |
|
| 1993 |
Khavari PA, Peterson CL, Tamkun JW, Mendel DB, Crabtree GR. BRG1 contains a conserved domain of the SWI2/SNF2 family necessary for normal mitotic growth and transcription. Nature. 366: 170-4. PMID 8232556 DOI: 10.1038/366170A0 |
0.523 |
|
| 1991 |
Mendel DB, Khavari PA, Conley PB, Graves MK, Hansen LP, Admon A, Crabtree GR. Characterization of a cofactor that regulates dimerization of a mammalian homeodomain protein. Science (New York, N.Y.). 254: 1762-7. PMID 1763325 DOI: 10.1126/Science.1763325 |
0.48 |
|
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