| Year |
Citation |
Score |
| 2023 |
Chen S, Shao F, Zeng J, Guo S, Wang L, Sun H, Lei JH, Lyu X, Gao S, Chen Q, Miao K, Xu X, Deng CX. Cullin-5 deficiency orchestrates the tumor microenvironment to promote mammary tumor development through CREB1-CCL2 signaling. Science Advances. 9: eabq1395. PMID 36662868 DOI: 10.1126/sciadv.abq1395 |
0.372 |
|
| 2022 |
Li J, Shu X, Xu J, Su SM, Chan UI, Mo L, Liu J, Zhang X, Adhav R, Chen Q, Wang Y, An T, Zhang X, Lyu X, Li X, ... ... Xu X, et al. S100A9-CXCL12 activation in BRCA1-mutant breast cancer promotes an immunosuppressive microenvironment associated with resistance to immunotherapy. Nature Communications. 13: 1481. PMID 35304461 DOI: 10.1038/s41467-022-29151-5 |
0.326 |
|
| 2022 |
Xu J, Su SM, Zhang X, Chan UI, Adhav R, Shu X, Liu J, Li J, Mo L, Wang Y, An T, Lei JH, Miao K, Deng CX, Xu X. ATP11B inhibits breast cancer metastasis in a mouse model by suppressing externalization of non-apoptotic phosphatidylserine. The Journal of Clinical Investigation. PMID 35025764 DOI: 10.1172/JCI149473 |
0.3 |
|
| 2021 |
Sun H, Zeng J, Miao Z, Lei KC, Huang C, Hu L, Su SM, Chan UI, Miao K, Zhang X, Zhang A, Guo S, Chen S, Meng Y, Deng M, ... ... Xu X, et al. Dissecting the heterogeneity and tumorigenesis of BRCA1 deficient mammary tumors via single cell RNA sequencing. Theranostics. 11: 9967-9987. PMID 34815798 DOI: 10.7150/thno.63995 |
0.32 |
|
| 2021 |
Lei JH, Lee MH, Miao K, Huang Z, Yao Z, Zhang A, Xu J, Zhao M, Huang Z, Zhang X, Chen S, Jiaying NG, Feng Y, Xing F, Chen P, ... ... Xu X, et al. Activation of FGFR2 Signaling Suppresses BRCA1 and Drives Triple-Negative Mammary Tumorigenesis That is Sensitive to Immunotherapy. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2100974. PMID 34514747 DOI: 10.1002/advs.202100974 |
0.34 |
|
| 2020 |
Liu J, Adhav R, Miao K, Su SM, Mo L, Chan UI, Zhang X, Xu J, Li J, Shu X, Zeng J, Zhang X, Lyu X, Pardeshi L, Tan K, ... ... Xu X, et al. Characterization of BRCA1-deficient premalignant tissues and cancers identifies Plekha5 as a tumor metastasis suppressor. Nature Communications. 11: 4875. PMID 32978388 DOI: 10.1038/s41467-020-18637-9 |
0.316 |
|
| 2020 |
Miao K, Lei JH, Valecha MV, Zhang A, Xu J, Wang L, Lyu X, Chen S, Miao Z, Zhang X, Su SM, Shao F, Rajendran BK, Bao J, Zeng J, ... ... Xu X, et al. NOTCH1 activation compensates BRCA1 deficiency and promotes triple-negative breast cancer formation. Nature Communications. 11: 3256. PMID 32591500 DOI: 10.1038/S41467-020-16936-9 |
0.442 |
|
| 2020 |
Zhang B, Lyu J, Yang EJ, Liu Y, Wu C, Pardeshi L, Tan K, Chen Q, Xu X, Deng CX, Shim JS. Class I histone deacetylase inhibition is synthetic lethal with BRCA1 deficiency in breast cancer cells. Acta Pharmaceutica Sinica. B. 10: 615-627. PMID 32322466 DOI: 10.1016/J.Apsb.2019.08.008 |
0.432 |
|
| 2020 |
Chen Q, Lei JH, Bao J, Wang H, Hao W, Li L, Peng C, Masuda T, Miao K, Xu J, Xu X, Deng CX. BRCA1 Deficiency Impairs Mitophagy and Promotes Inflammasome Activation and Mammary Tumor Metastasis. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). 7: 1903616. PMID 32195105 DOI: 10.1002/Advs.201903616 |
0.399 |
|
| 2020 |
Chen Q, Lei JH, Bao J, Wang H, Hao W, Li L, Peng C, Masuda T, Miao K, Xu J, Xu X, Deng C. BRCA1 Deficiency: BRCA1 Deficiency Impairs Mitophagy and Promotes Inflammasome Activation and Mammary Tumor Metastasis (Adv. Sci. 6/2020) Advanced Science. 7: 2070033. DOI: 10.1002/Advs.202070033 |
0.385 |
|
| 2019 |
Sun X, Zhang R, Liu M, Chen H, Chen L, Luo F, Zhang D, Huang J, Li F, Ni Z, Qi H, Su N, Jin M, Yang J, Tan Q, ... ... Xu X, et al. Rmrp mutation disrupts chondrogenesis and bone ossification in zebrafish model of cartilage-hair hypoplasia via enhanced Wnt/β-catenin signaling. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 31237961 DOI: 10.1002/Jbmr.3820 |
0.362 |
|
| 2018 |
Miao K, Zhang X, Su SM, Zeng J, Huang Z, Chan UI, Xu X, Deng CX. Optimizing CRISPR/Cas9 technology for precise correction of the Fgfr3-Gly374Arg mutation in achondroplasia in mice. The Journal of Biological Chemistry. PMID 30487289 DOI: 10.1074/Jbc.Ra118.006496 |
0.359 |
|
| 2018 |
Xu X, Chen E, Mo L, Zhang L, Shao F, Miao K, Liu J, Su SM, Valecha M, In Chan U, Zheng H, Chen M, Chen W, Chen Q, Fu H, et al. BRCA1 represses DNA replication initiation through antagonizing estrogen signaling and maintains genome stability in parallel with WEE1-MCM2 signaling during pregnancy. Human Molecular Genetics. PMID 30445628 DOI: 10.1093/Hmg/Ddy398 |
0.386 |
|
| 2018 |
Luo F, Xie Y, Wang Z, Huang J, Tan Q, Sun X, Li F, Li C, Liu M, Zhang D, Xu M, Su N, Ni Z, Jiang W, Chang J, ... ... Xu X, et al. Adeno-Associated Virus-Mediated RNAi against Mutant Alleles Attenuates Abnormal Calvarial Phenotypes in an Apert Syndrome Mouse Model. Molecular Therapy. Nucleic Acids. 13: 291-302. PMID 30321816 DOI: 10.1016/J.Omtn.2018.09.012 |
0.369 |
|
| 2018 |
Tan Q, Chen B, Wang Q, Xu W, Wang Y, Lin Z, Luo F, Huang S, Zhu Y, Su N, Jin M, Li C, Kuang L, Qi H, Ni Z, ... ... Xu X, et al. A novel FGFR1-binding peptide attenuates the degeneration of articular cartilage in adult mice. Osteoarthritis and Cartilage. PMID 30201491 DOI: 10.1016/J.Joca.2018.08.012 |
0.3 |
|
| 2018 |
Zhang B, Lyu J, Liu Y, Wu C, Yang EJ, Pardeshi L, Tan K, Wong KH, Chen Q, Xu X, Deng CX, Shim JS. BRCA1 deficiency sensitizes breast cancer cells to bromodomain and extra-terminal domain (BET) inhibition. Oncogene. PMID 30042414 DOI: 10.1038/S41388-018-0408-8 |
0.437 |
|
| 2018 |
Sun H, Miao Z, Zhang X, Chan UI, Su SM, Guo S, Wong CKH, Xu X, Deng CX. Single-cell RNA-Seq reveals cell heterogeneity and hierarchy within mouse mammary epithelia. The Journal of Biological Chemistry. PMID 29666189 DOI: 10.1074/Jbc.Ra118.002297 |
0.374 |
|
| 2018 |
Lahusen TJ, Kim SJ, Miao K, Huang Z, Xu X, Deng CX. BRCA1 function in the intra-S checkpoint is activated by acetylation via a pCAF/SIRT1 axis. Oncogene. PMID 29440709 DOI: 10.1038/S41388-018-0127-1 |
0.438 |
|
| 2017 |
Liu J, Adhav R, Xu X. Current Progresses of Single Cell DNA Sequencing in Breast Cancer Research. International Journal of Biological Sciences. 13: 949-960. PMID 28924377 DOI: 10.7150/Ijbs.19627 |
0.368 |
|
| 2017 |
Chen Q, Hao W, Xiao C, Wang R, Xu X, Lu H, Chen W, Deng CX. SIRT6 Is Essential for Adipocyte Differentiation by Regulating Mitotic Clonal Expansion. Cell Reports. 18: 3155-3166. PMID 28355567 DOI: 10.1016/J.Celrep.2017.03.006 |
0.327 |
|
| 2017 |
Zheng H, Shao F, Martin S, Xu X, Deng CX. WEE1 inhibition targets cell cycle checkpoints for triple negative breast cancers to overcome cisplatin resistance. Scientific Reports. 7: 43517. PMID 28262781 DOI: 10.1038/Srep43517 |
0.379 |
|
| 2016 |
Chisholm CL, Wang H, Wong AH, Vazquez-Ortiz G, Chen W, Xu X, Deng CX. Ammonium tetrathiomolybdate treatment targets the copper transporter ATP7A and enhances sensitivity of breast cancer to cisplatin. Oncotarget. PMID 27806319 DOI: 10.18632/Oncotarget.12992 |
0.408 |
|
| 2016 |
Cougnoux A, Cluzeau C, Mitra S, Li R, Williams I, Burkert K, Xu X, Wassif CA, Zheng W, Porter FD. Necroptosis in Niemann-Pick disease, type C1: a potential therapeutic target. Cell Death & Disease. 7: e2147. PMID 26986514 DOI: 10.1038/Cddis.2016.16 |
0.341 |
|
| 2016 |
Masuda T, Xu X, Dimitriadis EK, Lahusen T, Deng CX. "DNA Binding Region" of BRCA1 Affects Genetic Stability through modulating the Intra-S-Phase Checkpoint. International Journal of Biological Sciences. 12: 133-43. PMID 26884712 DOI: 10.7150/Ijbs.14242 |
0.376 |
|
| 2014 |
Wang RH, Lahusen TJ, Chen Q, Xu X, Jenkins LM, Leo E, Fu H, Aladjem M, Pommier Y, Appella E, Deng CX. SIRT1 deacetylates TopBP1 and modulates intra-S-phase checkpoint and DNA replication origin firing. International Journal of Biological Sciences. 10: 1193-202. PMID 25516717 DOI: 10.7150/Ijbs.11066 |
0.356 |
|
| 2014 |
Vassilopoulos A, Xiao C, Chisholm C, Chen W, Xu X, Lahusen TJ, Bewley C, Deng CX. Synergistic therapeutic effect of cisplatin and phosphatidylinositol 3-kinase (PI3K) inhibitors in cancer growth and metastasis of Brca1 mutant tumors. The Journal of Biological Chemistry. 289: 24202-14. PMID 25006250 DOI: 10.1074/Jbc.M114.567552 |
0.386 |
|
| 2014 |
Vazquez-Ortiz G, Chisholm C, Xu X, Lahusen TJ, Li C, Sakamuru S, Huang R, Thomas CJ, Xia M, Deng C. Drug repurposing screen identifies lestaurtinib amplifies the ability of the poly (ADP-ribose) polymerase 1 inhibitor AG14361 to kill breast cancer associated gene-1 mutant and wild type breast cancer cells. Breast Cancer Research : Bcr. 16: R67. PMID 24962108 DOI: 10.1186/Bcr3682 |
0.381 |
|
| 2013 |
Wang RH, Xu X, Kim HS, Xiao Z, Deng CX. SIRT1 deacetylates FOXA2 and is critical for Pdx1 transcription and β-cell formation. International Journal of Biological Sciences. 9: 934-46. PMID 24163589 DOI: 10.7150/Ijbs.7529 |
0.366 |
|
| 2013 |
Becherel OJ, Yeo AJ, Stellati A, Heng EY, Luff J, Suraweera AM, Woods R, Fleming J, Carrie D, McKinney K, Xu X, Deng C, Lavin MF. Senataxin plays an essential role with DNA damage response proteins in meiotic recombination and gene silencing. Plos Genetics. 9: e1003435. PMID 23593030 DOI: 10.1371/Journal.Pgen.1003435 |
0.358 |
|
| 2013 |
Jeong SM, Xiao C, Finley LW, Lahusen T, Souza AL, Pierce K, Li YH, Wang X, Laurent G, German NJ, Xu X, Li C, Wang RH, Lee J, Csibi A, et al. SIRT4 has tumor-suppressive activity and regulates the cellular metabolic response to DNA damage by inhibiting mitochondrial glutamine metabolism. Cancer Cell. 23: 450-63. PMID 23562301 DOI: 10.1016/J.Ccr.2013.02.024 |
0.348 |
|
| 2012 |
Xiao C, Wang RH, Lahusen TJ, Park O, Bertola A, Maruyama T, Reynolds D, Chen Q, Xu X, Young HA, Chen WJ, Gao B, Deng CX. Progression of chronic liver inflammation and fibrosis driven by activation of c-JUN signaling in Sirt6 mutant mice. The Journal of Biological Chemistry. 287: 41903-13. PMID 23076146 DOI: 10.1074/Jbc.M112.415182 |
0.371 |
|
| 2012 |
Vazquez-Ortiz G, Chisholm CL, Huang R, Li C, Xu X, Rui-Hong W, Deng C. Abstract 2744: Identification of synergistic effect of autophagy inhibitors and resveratrol on BRCA1 mutant cancer cells Cancer Research. 72: 2744-2744. DOI: 10.1158/1538-7445.Am2012-2744 |
0.439 |
|
| 2011 |
Kim HS, Vassilopoulos A, Wang RH, Lahusen T, Xiao Z, Xu X, Li C, Veenstra TD, Li B, Yu H, Ji J, Wang XW, Park SH, Cha YI, Gius D, et al. SIRT2 maintains genome integrity and suppresses tumorigenesis through regulating APC/C activity. Cancer Cell. 20: 487-99. PMID 22014574 DOI: 10.1016/J.Ccr.2011.09.004 |
0.418 |
|
| 2011 |
Zeng N, Li Y, He L, Xu X, Galicia V, Deng C, Stiles BL. Adaptive basal phosphorylation of eIF2α is responsible for resistance to cellular stress-induced cell death in Pten-null hepatocytes. Molecular Cancer Research : McR. 9: 1708-17. PMID 22009178 DOI: 10.1158/1541-7786.Mcr-11-0299 |
0.33 |
|
| 2011 |
Wang RH, Kim HS, Xiao C, Xu X, Gavrilova O, Deng CX. Hepatic Sirt1 deficiency in mice impairs mTorc2/Akt signaling and results in hyperglycemia, oxidative damage, and insulin resistance. The Journal of Clinical Investigation. 121: 4477-90. PMID 21965330 DOI: 10.1172/Jci46243 |
0.304 |
|
| 2011 |
Deng C, Kim H, Vassilopoulos A, Wang R, Lahusen T, Xiao Z, Xu X, Li C, Veenstra TD, Ji J, Wang X, Park S, Gius D. Abstract SY11-01: Knockout mouse models for sirtuins: Genome integrity, metabolism, and cancer Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Sy11-01 |
0.447 |
|
| 2010 |
Shukla V, Coumoul X, Lahusen T, Wang RH, Xu X, Vassilopoulos A, Xiao C, Lee MH, Man YG, Ouchi M, Ouchi T, Deng CX. BRCA1 affects global DNA methylation through regulation of DNMT1. Cell Research. 20: 1201-15. PMID 20820192 DOI: 10.1038/Cr.2010.128 |
0.429 |
|
| 2010 |
Kim HS, Xiao C, Wang RH, Lahusen T, Xu X, Vassilopoulos A, Vazquez-Ortiz G, Jeong WI, Park O, Ki SH, Gao B, Deng CX. Hepatic-specific disruption of SIRT6 in mice results in fatty liver formation due to enhanced glycolysis and triglyceride synthesis. Cell Metabolism. 12: 224-36. PMID 20816089 DOI: 10.1016/J.Cmet.2010.06.009 |
0.316 |
|
| 2010 |
Su N, Xu X, Li C, He Q, Zhao L, Li C, Chen S, Luo F, Yi L, Du X, Huang H, Deng C, Chen L. Generation of Fgfr3 conditional knockout mice. International Journal of Biological Sciences. 6: 327-32. PMID 20582225 DOI: 10.7150/Ijbs.6.327 |
0.359 |
|
| 2010 |
Bunting SF, Callén E, Wong N, Chen HT, Polato F, Gunn A, Bothmer A, Feldhahn N, Fernandez-Capetillo O, Cao L, Xu X, Deng CX, Finkel T, Nussenzweig M, Stark JM, et al. 53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks. Cell. 141: 243-54. PMID 20362325 DOI: 10.1016/J.Cell.2010.03.012 |
0.367 |
|
| 2010 |
Xu X, Ehdaie B, Ohara N, Yoshino T, Deng CX. Synergistic action of Smad4 and Pten in suppressing pancreatic ductal adenocarcinoma formation in mice Oncogene. 29: 674-686. PMID 19901970 DOI: 10.1038/Onc.2009.375 |
0.444 |
|
| 2010 |
Li Y, Fischler T, Xu X, Wang R, Kim H, Sengupta K, Vassilopoulos A, Lahusen T, Liu Q, Elledge S, Ried T, Deng C. Abstract 1964: Genetic instability and mammary tumor formation in mice carrying mammary-specific disruption of Chk1 Cancer Research. 70: 1964-1964. DOI: 10.1158/1538-7445.Am10-1964 |
0.492 |
|
| 2009 |
Kim SS, Cao L, Baek HJ, Lim SC, Li C, Wang RH, Xu X, Cho KH, Deng CX. Impaired skin and mammary gland development and increased gamma-irradiation-induced tumorigenesis in mice carrying a mutation of S1152-ATM phosphorylation site in Brca1. Cancer Research. 69: 9291-300. PMID 19996295 DOI: 10.1158/0008-5472.Can-09-2418 |
0.465 |
|
| 2008 |
Wang RH, Zheng Y, Kim HS, Xu X, Cao L, Luhasen T, Lee MH, Xiao C, Vassilopoulos A, Chen W, Gardner K, Man YG, Hung MC, Finkel T, Deng CX. Interplay among BRCA1, SIRT1, and Survivin during BRCA1-associated tumorigenesis. Molecular Cell. 32: 11-20. PMID 18851829 DOI: 10.1016/J.Molcel.2008.09.011 |
0.462 |
|
| 2008 |
Wang RH, Sengupta K, Li C, Kim HS, Cao L, Xiao C, Kim S, Xu X, Zheng Y, Chilton B, Jia R, Zheng ZM, Appella E, Wang XW, Ried T, et al. Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice. Cancer Cell. 14: 312-23. PMID 18835033 DOI: 10.1016/J.Ccr.2008.09.001 |
0.428 |
|
| 2008 |
Yin L, Du X, Li C, Xu X, Chen Z, Su N, Zhao L, Qi H, Li F, Xue J, Yang J, Jin M, Deng C, Chen L. A Pro253Arg mutation in fibroblast growth factor receptor 2 (Fgfr2) causes skeleton malformation mimicking human Apert syndrome by affecting both chondrogenesis and osteogenesis. Bone. 42: 631-43. PMID 18242159 DOI: 10.1016/J.Bone.2007.11.019 |
0.345 |
|
| 2007 |
Cao L, Xu X, Cao LL, Wang RH, Coumoul X, Kim SS, Deng CX. Absence of full-length Brca1 sensitizes mice to oxidative stress and carcinogen-induced tumorigenesis in the esophagus and forestomach. Carcinogenesis. 28: 1401-7. PMID 17363841 DOI: 10.1093/Carcin/Bgm060 |
0.476 |
|
| 2006 |
Kim SS, Cao L, Lim SC, Li C, Wang RH, Xu X, Bachelier R, Deng CX. Hyperplasia and spontaneous tumor development in the gynecologic system in mice lacking the BRCA1-Delta11 isoform. Molecular and Cellular Biology. 26: 6983-92. PMID 16943438 DOI: 10.1128/Mcb.00796-06 |
0.471 |
|
| 2006 |
Shukla V, Coumoul X, Cao L, Wang RH, Xiao C, Xu X, Andò S, Yakar S, Leroith D, Deng C. Absence of the full-length breast cancer-associated gene-1 leads to increased expression of insulin-like growth factor signaling axis members. Cancer Research. 66: 7151-7. PMID 16849561 DOI: 10.1158/0008-5472.Can-05-4570 |
0.468 |
|
| 2006 |
De Soto JA, Wang X, Tominaga Y, Wang RH, Cao L, Qiao W, Li C, Xu X, Skoumbourdis AP, Prindiville SA, Thomas CJ, Deng CX. The inhibition and treatment of breast cancer with poly (ADP-ribose) polymerase (PARP-1) inhibitors. International Journal of Biological Sciences. 2: 179-85. PMID 16810332 DOI: 10.7150/Ijbs.2.179 |
0.458 |
|
| 2006 |
Xu X, Kobayashi S, Qiao W, Li C, Xiao C, Radaeva S, Stiles B, Wang RH, Ohara N, Yoshino T, LeRoith D, Torbenson MS, Gores GJ, Wu H, Gao B, et al. Induction of intrahepatic cholangiocellular carcinoma by liver-specific disruption of Smad4 and Pten in mice. The Journal of Clinical Investigation. 116: 1843-52. PMID 16767220 DOI: 10.1172/Jci27282 |
0.432 |
|
| 2005 |
Bachelier R, Xu X, Li C, Qiao W, Furth PA, Lubet RA, Deng CX. Effect of bilateral oophorectomy on mammary tumor formation in BRCA1 mutant mice. Oncology Reports. 14: 1117-20. PMID 16211273 DOI: 10.3892/Or.14.5.1117 |
0.641 |
|
| 2005 |
Li C, Xu X, Nelson DK, Williams T, Kuehn MR, Deng CX. FGFR1 function at the earliest stages of mouse limb development plays an indispensable role in subsequent autopod morphogenesis. Development (Cambridge, England). 132: 4755-64. PMID 16207751 DOI: 10.1242/Dev.02065 |
0.36 |
|
| 2005 |
Turner JM, Mahadevaiah SK, Fernandez-Capetillo O, Nussenzweig A, Xu X, Deng CX, Burgoyne PS. Silencing of unsynapsed meiotic chromosomes in the mouse. Nature Genetics. 37: 41-7. PMID 15580272 DOI: 10.1038/Ng1484 |
0.34 |
|
| 2004 |
Turner JM, Aprelikova O, Xu X, Wang R, Kim S, Chandramouli GV, Barrett JC, Burgoyne PS, Deng CX. BRCA1, histone H2AX phosphorylation, and male meiotic sex chromosome inactivation. Current Biology : Cb. 14: 2135-42. PMID 15589157 DOI: 10.1016/J.Cub.2004.11.032 |
0.337 |
|
| 2004 |
Kim SS, Cao L, Li C, Xu X, Huber LJ, Chodosh LA, Deng CX. Uterus hyperplasia and increased carcinogen-induced tumorigenesis in mice carrying a targeted mutation of the Chk2 phosphorylation site in Brca1. Molecular and Cellular Biology. 24: 9498-507. PMID 15485917 DOI: 10.1128/Mcb.24.21.9498-9507.2004 |
0.485 |
|
| 2004 |
Deng CX, Xu X. Generation and analysis of Brca1 conditional knockout mice Methods in Molecular Biology (Clifton, N.J.). 280: 185-200. PMID 15187254 DOI: 10.1385/1-59259-788-2:185 |
0.459 |
|
| 2004 |
Wang X, Wang RH, Li W, Xu X, Hollander MC, Fornace AJ, Deng CX. Genetic interactions between Brca1 and Gadd45a in centrosome duplication, genetic stability, and neural tube closure. The Journal of Biological Chemistry. 279: 29606-14. PMID 15123655 DOI: 10.1074/Jbc.M312279200 |
0.45 |
|
| 2004 |
Wang Y, Cui F, Lv Y, Li C, Xu X, Deng C, Wang D, Sun Y, Hu G, Lang Z, Huang C, Yang X. HBsAg and HBx knocked into the p21 locus causes hepatocellular carcinoma in mice. Hepatology (Baltimore, Md.). 39: 318-24. PMID 14767984 DOI: 10.1002/Hep.20076 |
0.337 |
|
| 2003 |
Li W, Qiao W, Chen L, Xu X, Yang X, Li D, Li C, Brodie SG, Meguid MM, Hennighausen L, Deng CX. Squamous cell carcinoma and mammary abscess formation through squamous metaplasia in Smad4/Dpc4 conditional knockout mice. Development (Cambridge, England). 130: 6143-53. PMID 14597578 DOI: 10.1242/Dev.00820 |
0.37 |
|
| 2003 |
Xu X, Aprelikova O, Moens P, Deng CX, Furth PA. Impaired meiotic DNA-damage repair and lack of crossing-over during spermatogenesis in BRCA1 full-length isoform deficient mice Development. 130: 2001-2012. PMID 12642502 DOI: 10.1242/Dev.00410 |
0.617 |
|
| 2003 |
Bachelier R, Xu X, Wang X, Li W, Naramura M, Gu H, Deng CX. Normal lymphocyte development and thymic lymphoma formation in Brca1 exon-11-deficient mice. Oncogene. 22: 528-37. PMID 12555066 DOI: 10.1038/Sj.Onc.1206208 |
0.46 |
|
| 2003 |
Wang R, Li W, Xu X, Deng C. Mouse models for BRCA1-associated breast cancer Breast Cancer Research. 5: 3-3. DOI: 10.1186/Bcr662 |
0.495 |
|
| 2002 |
Weaver Z, Montagna C, Xu X, Howard T, Gadina M, Brodie SG, Deng CX, Ried T. Mammary tumors in mice conditionally mutant for Brca1 exhibit gross genomic instability and centrosome amplification yet display a recurring distribution of genomic imbalances that is similar to human breast cancer Oncogene. 21: 5097-5107. PMID 12140760 DOI: 10.1038/Sj.Onc.1205636 |
0.405 |
|
| 2002 |
Xu X, Qiao W, Li C, Deng CX. Generation of Fgfr1 conditional knockout mice. Genesis (New York, N.Y. : 2000). 32: 85-6. PMID 11857785 DOI: 10.1002/Gene.10028 |
0.306 |
|
| 2001 |
Yang X, Sun Y, Zhou J, Huang P, Huang C, Xu X, Li C, Gotay J, Chen L, Deng C. Establishment of murine Smad5 double knockout ES cells and the studies on their properties Science China-Life Sciences. 44: 121-129. PMID 18726428 DOI: 10.1007/Bf02879316 |
0.342 |
|
| 2001 |
Li C, Guo H, Xu X, Weinberg W, Deng CX. Fibroblast growth factor receptor 2 (Fgfr2) plays an important role in eyelid and skin formation and patterning Developmental Dynamics. 222: 471-483. PMID 11747081 DOI: 10.1002/Dvdy.1205 |
0.351 |
|
| 2001 |
Brodie SG, Xu X, Qiao W, Li WM, Cao L, Deng CX. Multiple genetic changes are associated with mammary tumorigenesis in Brca1 conditional knockout mice Oncogene. 20: 7514-7523. PMID 11709723 DOI: 10.1038/Sj.Onc.1204929 |
0.464 |
|
| 2001 |
Xu X, Qiao W, Linke SP, Cao L, Li WM, Furth PA, Harris CC, Deng CX. Genetic interactions between tumor suppressors Brca1 and p53 in apoptosis, cell cycle and tumorigenesis. Nature Genetics. 28: 266-71. PMID 11431698 DOI: 10.1038/90108 |
0.659 |
|
| 2001 |
Brodie SG, Xu X, Li C, Kuo A, Leder P, Deng CX. Inactivation of p53 tumor suppressor gene acts synergistically with c-neu oncogene in salivary gland tumorigenesis. Oncogene. 20: 1445-54. PMID 11313888 DOI: 10.1038/Sj.Onc.1204222 |
0.415 |
|
| 2001 |
Yang X, Chen L, Xu X, Li C, Huang C, Deng CX. TGF-β/Smad3 signals repress chondrocyte hypertrophic differentiation and are required for maintaining articular cartilage Journal of Cell Biology. 153: 35-46. PMID 11285272 DOI: 10.1083/Jcb.153.1.35 |
0.327 |
|
| 2001 |
Chen L, Li C, Qiao W, Xu X, Deng C. A Ser365→Cys mutation of fibroblast growth factor receptor 3 in mouse downregulates Ihh/PTHrP signals and causes severe achondroplasia Human Molecular Genetics. 10: 457-465. PMID 11181569 DOI: 10.1093/Hmg/10.5.457 |
0.359 |
|
| 2000 |
Zhou YX, Xu X, Chen L, Li C, Brodie SG, Deng CX. A Pro250Arg substitution in mouse Fgfr1 causes increased expression of Cbfa1 and premature fusion of calvarial sutures Human Molecular Genetics. 9: 2001-2008. PMID 10942429 DOI: 10.1093/Hmg/9.13.2001 |
0.397 |
|
| 2000 |
Xu X, Brodie SG, Yang X, Im YH, Parks WT, Chen L, Zhou YX, Weinstein M, Kim SJ, Deng CX. Haploid loss of the tumor suppressor Smad4/Dpc4 initiates gastric polyposis and cancer in mice. Oncogene. 19: 1868-74. PMID 10773876 DOI: 10.1038/Sj.Onc.1203504 |
0.397 |
|
| 1999 |
Xu X, Wagner KU, Larson D, Weaver Z, Li C, Ried T, Hennighausen L, Wynshaw-Boris A, Deng CX. Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation. Nature Genetics. 22: 37-43. PMID 10319859 DOI: 10.1038/8743 |
0.44 |
|
| 1999 |
Xu X, Weinstein M, Li C, Deng CX. Fibroblast growth factor receptors (FGFRs) and their roles in limb development Cell and Tissue Research. 296: 33-43. PMID 10199963 DOI: 10.1007/S004410051264 |
0.32 |
|
| 1999 |
Xu X, Weaver Z, Linke SP, Li C, Gotay J, Wang XW, Harris CC, Ried T, Deng CX. Centrosome amplification and a defective G2-M cell cycle checkpoint induce genetic instability in BRCA1 exon 11 isoform-deficient cells. Molecular Cell. 3: 389-95. PMID 10198641 DOI: 10.1016/S1097-2765(00)80466-9 |
0.429 |
|
| 1999 |
Xu X, Li C, Takahashi K, Slavkin HC, Shum L, Deng CX. Murine fibroblast growth factor receptor 1α isoforms mediate node regression and are essential for posterior mesoderm development Developmental Biology. 208: 293-306. PMID 10191046 DOI: 10.1006/Dbio.1999.9227 |
0.316 |
|
| 1998 |
Shen SX, Weaver Z, Xu X, Li C, Weinstein M, Chen L, Guan XY, Ried T, Deng CX. A targeted disruption of the murine Brca1 gene causes γ-irradiation hypersensitivity and genetic instability Oncogene. 17: 3115-3124. PMID 9872327 DOI: 10.1038/Sj.Onc.1202243 |
0.445 |
|
| 1998 |
Weinstein M, Yang X, Li C, Xu X, Gotay J, Deng CX. Failure of cgg cylinder elongation and mesoderm induction in mouse embryos lacking the tumor suppressor smad2 Proceedings of the National Academy of Sciences of the United States of America. 95: 9378-9383. PMID 9689088 DOI: 10.1073/Pnas.95.16.9378 |
0.371 |
|
| 1998 |
Yang X, Li C, Xu X, Deng C. The tumor suppressor SMAD4/DPC4 is essential for epiblast proliferation and mesoderm induction in mice Proceedings of the National Academy of Sciences of the United States of America. 95: 3667-3672. PMID 9520423 DOI: 10.1073/Pnas.95.7.3667 |
0.406 |
|
| 1997 |
Deng C, Bedford M, Li C, Xu X, Yang X, Dunmore J, Leder P. Fibroblast growth factor receptor-1 (FGFR-1) is essential for normal neural tube and limb development. Developmental Biology. 185: 42-54. PMID 9169049 DOI: 10.1006/Dbio.1997.8553 |
0.336 |
|
| 1996 |
Eicher EM, Washburn LL, Schork NJ, Lee BK, Shown EP, Xu X, Dredge RD, Pringle MJ, Page DC. Sex-determining genes on mouse autosomes identified by linkage analysis of C57BL/6J-YPOS sex reversal. Nature Genetics. 14: 206-9. PMID 8841197 DOI: 10.1038/Ng1096-206 |
0.318 |
|
| Show low-probability matches. |