| Year |
Citation |
Score |
| 2019 |
Yanda MK, Guggino WB, Cebotaru L. A new role for heat shock factor 27 in the pathophysiology of Clostridium difficile toxin B. American Journal of Physiology. Gastrointestinal and Liver Physiology. PMID 31709831 DOI: 10.1152/Ajpgi.00166.2019 |
0.336 |
|
| 2019 |
Bergbower EAS, Sabirzhanova I, Boinot C, Guggino WB, Cebotaru L. Restoration of F508-del Function by Transcomplementation: The Partners Meet in the Endoplasmic Reticulum. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 52: 1267-1279. PMID 31026390 DOI: 10.33594/000000089 |
0.321 |
|
| 2018 |
Sabirzhanova I, Boinot C, Guggino WB, Cebotaru L. Syntaxin 8 and the Endoplasmic Reticulum Processing of ΔF508-CFTR. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 51: 1489-1499. PMID 30485852 DOI: 10.1159/000495596 |
0.368 |
|
| 2018 |
Yanda MK, Liu Q, Cebotaru V, Guggino WB, Cebotaru L. Role of calcium in adult onset polycystic kidney disease. Cellular Signalling. PMID 30296477 DOI: 10.1016/J.Cellsig.2018.10.003 |
0.374 |
|
| 2018 |
Liu Q, Sabirzhanova I, Yanda MK, Bergbower EAS, Boinot C, Guggino WB, Cebotaru L. Rescue of CFTR NBD2 mutants N1303K and S1235R is influenced by the functioning of the autophagosome. Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society. PMID 29936070 DOI: 10.1016/J.Jcf.2018.05.016 |
0.394 |
|
| 2018 |
Krishnan V, Park SA, Shin SS, Alon L, Tressler CM, Stokes W, Banerjee J, Sorrell ME, Tian Y, Fridman GY, Celnik P, Pevsner J, Guggino WB, Gilad AA, Pelled G. Wireless control of cellular function by activation of a novel protein responsive to electromagnetic fields. Scientific Reports. 8: 8764. PMID 29884813 DOI: 10.1038/S41598-018-27087-9 |
0.316 |
|
| 2018 |
Bergbower E, Boinot C, Sabirzhanova I, Guggino WB, Cebotaru L. The CFTR-Associated Ligand Arrests the Trafficking of the Mutant ΔF508 CFTR Channel in the ER Contributing to Cystic Fibrosis Cellular Physiology and Biochemistry. 45: 639-655. PMID 29402832 DOI: 10.1159/000487120 |
0.797 |
|
| 2017 |
Yanda MK, Liu Q, Cebotaru V, Guggino WB, Cebotaru L. Histone deacetylase 6 Inhibition reduces cysts by decreasing via cAMP and Ca2+ in knockout mouse models of polycystic kidney disease. The Journal of Biological Chemistry. PMID 28887310 DOI: 10.1074/Jbc.M117.803775 |
0.353 |
|
| 2016 |
Wang H, Cebotaru L, Lee HW, Yang Q, Pollard BS, Pollard HB, Guggino WB. CFTR Controls the Activity of NF-κB by Enhancing the Degradation of TRADD. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 40: 1063-1078. PMID 27960153 DOI: 10.1159/000453162 |
0.489 |
|
| 2016 |
Cebotaru L, Liu Q, Yanda M, Boinot C, Outeda P, Huso DL, Watnick T, Guggino WB, Cebotaru V. Inhibition of histone deacetylase 6 activity reduces cyst growth in polycystic kidney disease. Kidney International. PMID 27165822 DOI: 10.1016/J.Kint.2016.01.026 |
0.342 |
|
| 2016 |
Lopes-Pacheco M, Sabirzhanova I, Rapino D, Morales MM, Guggino WB, Cebotaru L. Correctors rescue CFTR mutations in nucleotide-binding domain 1 (NBD1) by modulating proteostasis. Chembiochem : a European Journal of Chemical Biology. PMID 26864378 DOI: 10.1002/Cbic.201500620 |
0.395 |
|
| 2016 |
Veit G, Avramescu RG, Chiang AN, Houck SA, Cai Z, Peters KW, Hong JS, Pollard HB, Guggino WB, Balch WE, Skach WR, Cutting GR, Frizzell RA, Sheppard DN, Cyr DM, et al. From CFTR biology toward combinatorial pharmacotherapy: expanded classification of cystic fibrosis mutations. Molecular Biology of the Cell. 27: 424-33. PMID 26823392 DOI: 10.1091/Mbc.E14-04-0935 |
0.366 |
|
| 2016 |
Cebotaru L, Boinot C, Sabirzhanova I, Guggino W. 10 Gene therapy to rescue of premature stop mutations R1162X and W1282X Journal of Cystic Fibrosis. 15: S54. DOI: 10.1016/S1569-1993(16)30250-8 |
0.303 |
|
| 2015 |
Lopes-Pacheco M, Boinot C, Sabirzhanova I, Morales MM, Guggino WB, Cebotaru L. Combination of correctors rescue ΔF508-CFTR by reducing its association with Hsp 40 and 27. The Journal of Biological Chemistry. PMID 26336106 DOI: 10.1074/Jbc.M115.671925 |
0.389 |
|
| 2015 |
Sabirzhanova I, Lopes Pacheco M, Rapino D, Grover R, Handa JT, Guggino WB, Cebotaru L. Rescuing Trafficking Mutants of the ATP-binding Cassette Protein, ABCA4, with Small Molecule Correctors as a Treatment for Stargardt Eye Disease. The Journal of Biological Chemistry. 290: 19743-55. PMID 26092729 DOI: 10.1074/Jbc.M115.647685 |
0.368 |
|
| 2015 |
Rapino D, Sabirzhanova I, Lopes-Pacheco M, Grover R, Guggino WB, Cebotaru L. Rescue of NBD2 mutants N1303K and S1235R of CFTR by small-molecule correctors and transcomplementation. Plos One. 10: e0119796. PMID 25799511 DOI: 10.1371/Journal.Pone.0119796 |
0.356 |
|
| 2014 |
Cebotaru L, Guggino WB. Complement yourself: Transcomplementation rescues partially folded mutant proteins. Biophysical Reviews. 6: 169-180. PMID 24949105 DOI: 10.1007/S12551-014-0137-3 |
0.463 |
|
| 2014 |
Schuster BS, Kim AJ, Kays JC, Kanzawa MM, Guggino WB, Boyle MP, Rowe SM, Muzyczka N, Suk JS, Hanes J. Overcoming the cystic fibrosis sputum barrier to leading adeno-associated virus gene therapy vectors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 1484-93. PMID 24869933 DOI: 10.1038/Mt.2014.89 |
0.304 |
|
| 2014 |
Peruchetti DB, Cheng J, Caruso-Neves C, Guggino WB. Mis-regulation of mammalian target of rapamycin (mTOR) complexes induced by albuminuria in proximal tubules. The Journal of Biological Chemistry. 289: 16790-801. PMID 24790108 DOI: 10.1074/Jbc.M114.549717 |
0.313 |
|
| 2014 |
Cebotaru V, Cebotaru L, Kim H, Chiaravalli M, Boletta A, Qian F, Guggino WB. Polycystin-1 negatively regulates Polycystin-2 expression via the aggresome/autophagosome pathway. The Journal of Biological Chemistry. 289: 6404-14. PMID 24459142 DOI: 10.1074/Jbc.M113.501205 |
0.362 |
|
| 2014 |
Suk JS, Kim AJ, Trehan K, Schneider CS, Cebotaru L, Woodward OM, Boylan NJ, Boyle MP, Lai SK, Guggino WB, Hanes J. Lung gene therapy with highly compacted DNA nanoparticles that overcome the mucus barrier. Journal of Controlled Release : Official Journal of the Controlled Release Society. 178: 8-17. PMID 24440664 DOI: 10.1016/J.Jconrel.2014.01.007 |
0.653 |
|
| 2013 |
Cheng J, Guggino W. Ubiquitination and degradation of CFTR by the E3 ubiquitin ligase MARCH2 through its association with adaptor proteins CAL and STX6. Plos One. 8: e68001. PMID 23818989 DOI: 10.1371/Journal.Pone.0068001 |
0.372 |
|
| 2013 |
Lee HW, Cheng J, Kovbasnjuk O, Donowitz M, Guggino WB. Insulin-like growth factor 1 (IGF-1) enhances the protein expression of CFTR. Plos One. 8: e59992. PMID 23555857 DOI: 10.1371/Journal.Pone.0059992 |
0.575 |
|
| 2013 |
Woodward OM, Tukaye DN, Cui J, Greenwell P, Constantoulakis LM, Parker BS, Rao A, Köttgen M, Maloney PC, Guggino WB. Gout-causing Q141K mutation in ABCG2 leads to instability of the nucleotide-binding domain and can be corrected with small molecules. Proceedings of the National Academy of Sciences of the United States of America. 110: 5223-8. PMID 23493553 DOI: 10.1073/Pnas.1214530110 |
0.77 |
|
| 2013 |
Cebotaru L, Woodward O, Cebotaru V, Guggino WB. Transcomplementation by a truncation mutant of cystic fibrosis transmembrane conductance regulator (CFTR) EnhancesδF508 processing through a biomolecular interaction Journal of Biological Chemistry. 288: 10505-10512. PMID 23463513 DOI: 10.1074/Jbc.M112.420489 |
0.719 |
|
| 2013 |
Tukaye DN, Kwon SH, Guggino WB. The GAP portion of Pseudomonas aeruginosa type III secreted toxin ExoS upregulates total and surface levels of wild type CFTR. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 31: 153-65. PMID 23428533 DOI: 10.1159/000343357 |
0.763 |
|
| 2013 |
Ramalingam S, London V, Kandavelou K, Cebotaru L, Guggino W, Civin C, Chandrasegaran S. Generation and genetic engineering of human induced pluripotent stem cells using designed zinc finger nucleases. Stem Cells and Development. 22: 595-610. PMID 22931452 DOI: 10.1089/Scd.2012.0245 |
0.312 |
|
| 2013 |
Woodward OM, Guggino WB. Anion Channels Seldin and Geibisch's the Kidney. 1: 1019-1045. DOI: 10.1016/B978-0-12-381462-3.00031-8 |
0.639 |
|
| 2012 |
Prota LF, Cebotaru L, Cheng J, Wright J, Vij N, Morales MM, Guggino WB. Dexamethasone regulates CFTR expression in Calu-3 cells with the involvement of chaperones HSP70 and HSP90. Plos One. 7: e47405. PMID 23272037 DOI: 10.1371/Journal.Pone.0047405 |
0.401 |
|
| 2012 |
Ramsey BW, Banks-Schlegel S, Accurso FJ, Boucher RC, Cutting GR, Engelhardt JF, Guggino WB, Karp CL, Knowles MR, Kolls JK, LiPuma JJ, Lynch S, McCray PB, Rubenstein RC, Singh PK, et al. Future directions in early cystic fibrosis lung disease research: an NHLBI workshop report. American Journal of Respiratory and Critical Care Medicine. 185: 887-92. PMID 22312017 DOI: 10.1164/Rccm.201111-2068Ws |
0.311 |
|
| 2012 |
Cebotaru L, Woodward O, Guggino W. WS15.5 Transcomplementation by a truncation mutant of CFTR, Δ27-264 CFTR, rescues both trafficking and chloride channel function of ΔF508 CFTR Journal of Cystic Fibrosis. 11: S34. DOI: 10.1016/S1569-1993(12)60107-6 |
0.421 |
|
| 2011 |
Peruchetti DB, Pinheiro AA, Landgraf SS, Wengert M, Takiya CM, Guggino WB, Caruso-Neves C. (Na+ + K+)-ATPase is a target for phosphoinositide 3-kinase/protein kinase B and protein kinase C pathways triggered by albumin. The Journal of Biological Chemistry. 286: 45041-7. PMID 22057272 DOI: 10.1074/Jbc.M111.260737 |
0.339 |
|
| 2011 |
Liang L, Woodward OM, Chen Z, Cotter R, Guggino WB. A novel role of protein tyrosine kinase2 in mediating chloride secretion in human airway epithelial cells. Plos One. 6: e21991. PMID 21765932 DOI: 10.1371/Journal.Pone.0021991 |
0.714 |
|
| 2011 |
Santoso NG, Cebotaru L, Guggino WB. Polycystin-1, 2, and STIM1 interact with IP(3)R to modulate ER Ca release through the PI3K/Akt pathway. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 27: 715-26. PMID 21691089 DOI: 10.1159/000330080 |
0.72 |
|
| 2011 |
Bomberger JM, Guggino WB, Stanton BA. Methods to monitor cell surface expression and endocytic trafficking of CFTR in polarized epithelial cells. Methods in Molecular Biology (Clifton, N.J.). 741: 271-83. PMID 21594791 DOI: 10.1007/978-1-61779-117-8_18 |
0.414 |
|
| 2011 |
Peters KW, Okiyoneda T, Balch WE, Braakman I, Brodsky JL, Guggino WB, Penland CM, Pollard HB, Sorscher EJ, Skach WR, Thomas PJ, Lukacs GL, Frizzell RA. CFTR Folding Consortium: methods available for studies of CFTR folding and correction. Methods in Molecular Biology (Clifton, N.J.). 742: 335-53. PMID 21547742 DOI: 10.1007/978-1-61779-120-8_20 |
0.379 |
|
| 2011 |
Al-Shanti N, Faulkner SH, Saini A, Loram I, Stewart CE, Zhang Z, Li X, Liu G, Gao L, Guo C, Kong T, Wang H, Gao R, Wang Z, Zhu X, ... ... Guggino WB, et al. Contents Vol. 27, 2011 Cellular Physiology and Biochemistry. 27. DOI: 10.1159/000330089 |
0.674 |
|
| 2010 |
Lassance-Soares RM, Cheng J, Krasnov K, Cebotaru L, Cutting GR, Souza-Menezes J, Morales MM, Guggino WB. The hypertonic environment differentially regulates wild-type CFTR and TNR-CFTR chloride channels. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 26: 577-86. PMID 21063095 DOI: 10.1159/000322325 |
0.424 |
|
| 2010 |
Woodward OM, Li Y, Yu S, Greenwell P, Wodarczyk C, Boletta A, Guggino WB, Qian F. Identification of a polycystin-1 cleavage product, P100, that regulates store operated Ca entry through interactions with STIM1. Plos One. 5: e12305. PMID 20808796 DOI: 10.1371/Journal.Pone.0012305 |
0.695 |
|
| 2010 |
Kwon Y, Kim SH, Ronderos DS, Lee Y, Akitake B, Woodward OM, Guggino WB, Smith DP, Montell C. Drosophila TRPA1 channel is required to avoid the naturally occurring insect repellent citronellal. Current Biology : Cb. 20: 1672-8. PMID 20797863 DOI: 10.1016/J.Cub.2010.08.016 |
0.689 |
|
| 2010 |
Gena P, Calamita G, Guggino WB. Cadmium impairs albumin reabsorption by down-regulating megalin and ClC5 channels in renal proximal tubule cells. Environmental Health Perspectives. 118: 1551-6. PMID 20576581 DOI: 10.1289/Ehp.0901874 |
0.303 |
|
| 2010 |
Kim SH, Lee Y, Akitake B, Woodward OM, Guggino WB, Montell C. Drosophila TRPA1 channel mediates chemical avoidance in gustatory receptor neurons. Proceedings of the National Academy of Sciences of the United States of America. 107: 8440-5. PMID 20404155 DOI: 10.1073/Pnas.1001425107 |
0.677 |
|
| 2010 |
Atwell S, Brouillette CG, Conners K, Emtage S, Gheyi T, Guggino WB, Hendle J, Hunt JF, Lewis HA, Lu F, Protasevich II, Rodgers LA, Romero R, Wasserman SR, Weber PC, et al. Structures of a minimal human CFTR first nucleotide-binding domain as a monomer, head-to-tail homodimer, and pathogenic mutant. Protein Engineering, Design & Selection : Peds. 23: 375-84. PMID 20150177 DOI: 10.1093/Protein/Gzq004 |
0.355 |
|
| 2010 |
Cheng J, Cebotaru V, Cebotaru L, Guggino WB. Syntaxin 6 and CAL mediate the degradation of the cystic fibrosis transmembrane conductance regulator. Molecular Biology of the Cell. 21: 1178-87. PMID 20130090 DOI: 10.1091/Mbc.E09-03-0229 |
0.415 |
|
| 2010 |
Hoque KM, Woodward OM, van Rossum DB, Zachos NC, Chen L, Leung GP, Guggino WB, Guggino SE, Tse CM. Epac1 mediates protein kinase A-independent mechanism of forskolin-activated intestinal chloride secretion. The Journal of General Physiology. 135: 43-58. PMID 20038525 DOI: 10.1083/Jcb1877Oia18 |
0.704 |
|
| 2010 |
Lewis HA, Wang C, Zhao X, Hamuro Y, Conners K, Kearins MC, Lu F, Sauder JM, Molnar KS, Coales SJ, Maloney PC, Guggino WB, Wetmore DR, Weber PC, Hunt JF. Structure and dynamics of NBD1 from CFTR characterized using crystallography and hydrogen/deuterium exchange mass spectrometry Journal of Molecular Biology. 396: 406-430. PMID 19944699 DOI: 10.1016/J.Jmb.2009.11.051 |
0.322 |
|
| 2010 |
Zhou B, Zhuang J, Gu D, Wang H, Cebotaru L, Guggino WB, Cai H. WNK4 enhances the degradation of NCC through a sortilin-mediated lysosomal pathway. Journal of the American Society of Nephrology : Jasn. 21: 82-92. PMID 19875813 DOI: 10.1681/Asn.2008121275 |
0.361 |
|
| 2009 |
Li Y, Santoso NG, Yu S, Woodward OM, Qian F, Guggino WB. Polycystin-1 interacts with inositol 1,4,5-trisphosphate receptor to modulate intracellular Ca2+ signaling with implications for polycystic kidney disease. The Journal of Biological Chemistry. 284: 36431-41. PMID 19854836 DOI: 10.1074/Jbc.M109.068916 |
0.767 |
|
| 2009 |
Woodward OM, Köttgen A, Coresh J, Boerwinkle E, Guggino WB, Köttgen M. Identification of a urate transporter, ABCG2, with a common functional polymorphism causing gout. Proceedings of the National Academy of Sciences of the United States of America. 106: 10338-42. PMID 19506252 DOI: 10.1073/Pnas.0901249106 |
0.655 |
|
| 2009 |
Liang L, MacDonald K, Schwiebert EM, Zeitlin PL, Guggino WB. Spiperone, identified through compound screening, activates calcium-dependent chloride secretion in the airway. American Journal of Physiology. Cell Physiology. 296: C131-41. PMID 18987251 DOI: 10.1152/Ajpcell.00346.2008 |
0.414 |
|
| 2008 |
Krasnov KV, Tzetis M, Cheng J, Guggino WB, Cutting GR. Localization studies of rare missense mutations in cystic fibrosis transmembrane conductance regulator (CFTR) facilitate interpretation of genotype-phenotype relationships. Human Mutation. 29: 1364-72. PMID 18951463 DOI: 10.1002/Humu.20866 |
0.36 |
|
| 2008 |
Souza-Menezes J, Tukaye DN, Novaira HJ, Guggino WB, Morales MM. Small nuclear RNAs U11 and U12 modulate expression of TNR-CFTR mRNA in mammalian kidneys. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 22: 93-100. PMID 18769035 DOI: 10.1159/000149786 |
0.741 |
|
| 2008 |
Cebotaru L, Vij N, Ciobanu I, Wright J, Flotte T, Guggino WB. Cystic fibrosis transmembrane regulator missing the first four transmembrane segments increases wild type and DeltaF508 processing. The Journal of Biological Chemistry. 283: 21926-33. PMID 18508776 DOI: 10.1074/Jbc.M709156200 |
0.422 |
|
| 2008 |
Cebotaru L, Vij N, Ciobanu I, Wright J, Guggino W. CFTR missing the first four transmembrane segments enhances wild type and ΔF508 CFTR processing Journal of Cystic Fibrosis. 7: S16. DOI: 10.1016/S1569-1993(08)60060-0 |
0.303 |
|
| 2008 |
Wang Y, Guggino WB, Fong P. Anion Channels Seldin and Giebisch's the Kidney. 769-792. DOI: 10.1016/B978-012088488-9.50032-2 |
0.442 |
|
| 2007 |
Kwon SH, Pollard H, Guggino WB. Knockdown of NHERF1 enhances degradation of temperature rescued DeltaF508 CFTR from the cell surface of human airway cells. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 20: 763-72. PMID 17982258 DOI: 10.1159/000110436 |
0.697 |
|
| 2007 |
Souza-Menezes J, Morales MM, Tukaye DN, Guggino SE, Guggino WB. Absence of ClC5 in knockout mice leads to glycosuria, impaired renal glucose handling and low proximal tubule GLUT2 protein expression. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 20: 455-64. PMID 17762172 DOI: 10.1159/000107529 |
0.718 |
|
| 2007 |
Fischer AC, Smith CI, Cebotaru L, Zhang X, Askin FB, Wright J, Guggino SE, Adams RJ, Flotte T, Guggino WB. Expression of a truncated cystic fibrosis transmembrane conductance regulator with an AAV5-pseudotyped vector in primates. Molecular Therapy : the Journal of the American Society of Gene Therapy. 15: 756-63. PMID 17299412 DOI: 10.1038/Sj.Mt.6300059 |
0.344 |
|
| 2007 |
Wolde M, Fellows A, Cheng J, Kivenson A, Coutermarsh B, Talebian L, Karlson K, Piserchio A, Mierke DF, Stanton BA, Guggino WB, Madden DR. Targeting CAL as a negative regulator of DeltaF508-CFTR cell-surface expression: an RNA interference and structure-based mutagenetic approach. The Journal of Biological Chemistry. 282: 8099-109. PMID 17158866 DOI: 10.1074/Jbc.M611049200 |
0.451 |
|
| 2006 |
Caruso-Neves C, Pinheiro AA, Cai H, Souza-Menezes J, Guggino WB. PKB and megalin determine the survival or death of renal proximal tubule cells. Proceedings of the National Academy of Sciences of the United States of America. 103: 18810-5. PMID 17121993 DOI: 10.1073/Pnas.0605029103 |
0.331 |
|
| 2006 |
Ikeda M, Fong P, Cheng J, Boletta A, Qian F, Zhang XM, Cai H, Germino GG, Guggino WB. A regulatory role of polycystin-1 on cystic fibrosis transmembrane conductance regulator plasma membrane expression. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 18: 9-20. PMID 16914886 DOI: 10.1159/000095133 |
0.41 |
|
| 2006 |
Pollard HB, Eidelman O, Jozwik C, Huang W, Srivastava M, Ji XD, McGowan B, Norris CF, Todo T, Darling T, Mogayzel PJ, Zeitlin PL, Wright J, Guggino WB, Metcalf E, et al. De novo biosynthetic profiling of high abundance proteins in cystic fibrosis lung epithelial cells. Molecular & Cellular Proteomics : McP. 5: 1628-37. PMID 16829594 DOI: 10.1074/Mcp.M600091-Mcp200 |
0.36 |
|
| 2006 |
Guggino WB, Stanton BA. New insights into cystic fibrosis: molecular switches that regulate CFTR. Nature Reviews. Molecular Cell Biology. 7: 426-36. PMID 16723978 DOI: 10.1038/Nrm1949 |
0.398 |
|
| 2006 |
Cai H, Cebotaru V, Wang YH, Zhang XM, Cebotaru L, Guggino SE, Guggino WB. WNK4 kinase regulates surface expression of the human sodium chloride cotransporter in mammalian cells. Kidney International. 69: 2162-70. PMID 16688122 DOI: 10.1038/Sj.Ki.5000333 |
0.545 |
|
| 2006 |
Novaira HJ, Ornellas DS, Ortiga-Carvalho TM, Zhang XM, Souza-Menezes J, Guggino SE, Guggino WB, Morales MM. Atrial natriuretic peptide modulates cystic fibrosis transmembrane conductance regulator chloride channel expression in rat proximal colon and human intestinal epithelial cells. The Journal of Endocrinology. 189: 155-65. PMID 16614390 DOI: 10.1677/Joe.1.06460 |
0.417 |
|
| 2006 |
Wright JM, Merlo CA, Reynolds JB, Zeitlin PL, Garcia JG, Guggino WB, Boyle MP. Respiratory epithelial gene expression in patients with mild and severe cystic fibrosis lung disease. American Journal of Respiratory Cell and Molecular Biology. 35: 327-36. PMID 16614352 DOI: 10.1165/Rcmb.2005-0359Oc |
0.348 |
|
| 2006 |
van den Hove MF, Croizet-Berger K, Jouret F, Guggino SE, Guggino WB, Devuyst O, Courtoy PJ. The loss of the chloride channel, ClC-5, delays apical iodide efflux and induces a euthyroid goiter in the mouse thyroid gland. Endocrinology. 147: 1287-96. PMID 16306076 DOI: 10.1210/En.2005-1149 |
0.353 |
|
| 2006 |
Beitz E, Liu K, Ikeda M, Guggino WB, Agre P, Yasui M. Determinants of AQP6 trafficking to intracellular sites versus the plasma membrane in transfected mammalian cells. Biology of the Cell / Under the Auspices of the European Cell Biology Organization. 98: 101-9. PMID 15892693 DOI: 10.1042/Bc20050025 |
0.305 |
|
| 2006 |
Cebotaru L, Flotté T, Guggino W. 56 AAV Δ264CFTR enhances wt CFTR expression and maturation of ΔF508CFTR Journal of Cystic Fibrosis. 5: S13. DOI: 10.1016/S1569-1993(06)80052-4 |
0.324 |
|
| 2006 |
Cebotaru L, Flotte TR, Guggino WB. 498. AAV Δ264CFTR Enhances Maturation of ΔF508CFTR and wt CFTR Expression Molecular Therapy. 13: S193. DOI: 10.1016/J.Ymthe.2006.08.568 |
0.344 |
|
| 2005 |
Caruso-Neves C, Kwon SH, Guggino WB. Albumin endocytosis in proximal tubule cells is modulated by angiotensin II through an AT2 receptor-mediated protein kinase B activation. Proceedings of the National Academy of Sciences of the United States of America. 102: 17513-8. PMID 16293694 DOI: 10.1073/Pnas.0507255102 |
0.663 |
|
| 2005 |
Li Y, Wright JM, Qian F, Germino GG, Guggino WB. Polycystin 2 interacts with type I inositol 1,4,5-trisphosphate receptor to modulate intracellular Ca2+ signaling. The Journal of Biological Chemistry. 280: 41298-306. PMID 16223735 DOI: 10.1074/Jbc.M510082200 |
0.343 |
|
| 2005 |
Flotte TR, Schwiebert EM, Zeitlin PL, Carter BJ, Guggino WB. Correlation between DNA transfer and cystic fibrosis airway epithelial cell correction after recombinant adeno-associated virus serotype 2 gene therapy. Human Gene Therapy. 16: 921-8. PMID 16076250 DOI: 10.1089/Hum.2005.16.921 |
0.374 |
|
| 2005 |
Wang Y, Cai H, Cebotaru L, Hryciw DH, Weinman EJ, Donowitz M, Guggino SE, Guggino WB. ClC-5: role in endocytosis in the proximal tubule. American Journal of Physiology. Renal Physiology. 289: F850-62. PMID 15942052 DOI: 10.1152/Ajprenal.00011.2005 |
0.572 |
|
| 2005 |
Hara-Chikuma M, Wang Y, Guggino SE, Guggino WB, Verkman AS. Impaired acidification in early endosomes of ClC-5 deficient proximal tubule. Biochemical and Biophysical Research Communications. 329: 941-6. PMID 15752747 DOI: 10.1016/J.Bbrc.2005.02.060 |
0.512 |
|
| 2005 |
Cheng J, Wang H, Guggino WB. Regulation of cystic fibrosis transmembrane regulator trafficking and protein expression by a Rho family small GTPase TC10. The Journal of Biological Chemistry. 280: 3731-9. PMID 15546864 DOI: 10.1074/Jbc.M410026200 |
0.409 |
|
| 2005 |
Lewis HA, Zhao X, Wang C, Sauder JM, Rooney I, Noland BW, Lorimer D, Kearins MC, Conners K, Condon B, Maloney PC, Guggino WB, Hunt JF, Emtage S. Impact of the deltaF508 mutation in first nucleotide-binding domain of human cystic fibrosis transmembrane conductance regulator on domain folding and structure. The Journal of Biological Chemistry. 280: 1346-53. PMID 15528182 DOI: 10.1074/Jbc.M410968200 |
0.379 |
|
| 2004 |
Guggino WB. The cystic fibrosis transmembrane regulator forms macromolecular complexes with PDZ domain scaffold proteins. Proceedings of the American Thoracic Society. 1: 28-32. PMID 16113408 DOI: 10.1513/pats.2306011 |
0.309 |
|
| 2004 |
Kwon SH, Guggino WB. Multiple sequences in the C terminus of MaxiK channels are involved in expression, movement to the cell surface, and apical localization. Proceedings of the National Academy of Sciences of the United States of America. 101: 15237-42. PMID 15469924 DOI: 10.1073/Pnas.0404877101 |
0.703 |
|
| 2004 |
Guggino WB, Banks-Schlegel SP. Macromolecular interactions and ion transport in cystic fibrosis. American Journal of Respiratory and Critical Care Medicine. 170: 815-20. PMID 15447951 DOI: 10.1164/Rccm.200403-381Ws |
0.401 |
|
| 2004 |
Sirninger J, Muller C, Braag S, Tang Q, Yue H, Detrisac C, Ferkol T, Guggino WB, Flotte TR. Functional characterization of a recombinant adeno-associated virus 5-pseudotyped cystic fibrosis transmembrane conductance regulator vector Human Gene Therapy. 15: 832-841. PMID 15353038 DOI: 10.1089/Hum.2004.15.832 |
0.362 |
|
| 2004 |
Zeitlin PL, Boyle MP, Guggino WB, Molina L. A phase I trial of intranasal Moli1901 for cystic fibrosis. Chest. 125: 143-9. PMID 14718433 DOI: 10.1378/Chest.125.1.143 |
0.339 |
|
| 2004 |
Lewis HA, Buchanan SG, Burley SK, Conners K, Dickey M, Dorwart M, Fowler R, Gao X, Guggino WB, Hendrickson WA, Hunt JF, Kearins MC, Lorimer D, Maloney PC, Post KW, et al. Structure of nucleotide-binding domain 1 of the cystic fibrosis transmembrane conductance regulator. The Embo Journal. 23: 282-93. PMID 14685259 DOI: 10.1038/Sj.Emboj.7600040 |
0.369 |
|
| 2004 |
Wright JM, Zeitlin PL, Cebotaru L, Guggino SE, Guggino WB. Gene expression profile analysis of 4-phenylbutyrate treatment of IB3-1 bronchial epithelial cell line demonstrates a major influence on heat-shock proteins. Physiological Genomics. 16: 204-11. PMID 14583596 DOI: 10.1152/Physiolgenomics.00160.2003 |
0.381 |
|
| 2004 |
Cheng J, Wang H, Guggino WB. Modulation of mature cystic fibrosis transmembrane regulator protein by the PDZ domain protein CAL. The Journal of Biological Chemistry. 279: 1892-8. PMID 14570915 DOI: 10.1074/Jbc.M308640200 |
0.429 |
|
| 2004 |
Fischer AC, Smith CI, Flotte TR, Guggino WB. 493. Enhanced Transgene Transfer and Expression by an Endobronchially Delivered Pseudotyped AAV2/5 Vector Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.412 |
0.31 |
|
| 2004 |
Munson KL, Tatalick LM, Smith CI, Fischer AC, Anklesaria P, Carter BJ, Guggino WB. 489. Comparison of AAV2 and AAV2/5 CFTR vectors in the lungs of cynomolgus macaques Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.399 |
0.367 |
|
| 2003 |
Santos Ornellas D, Grozovsky R, Goldenberg RC, Carvalho DP, Fong P, Guggino WB, Morales M. Thyroid hormone modulates CIC-2 chloride channel gene expression in rat renal proximal tubules Journal of Endocrinology. 178: 503-511. PMID 12967341 DOI: 10.1677/Joe.0.1780503 |
0.325 |
|
| 2003 |
Hryciw DH, Wang Y, Devuyst O, Pollock CA, Poronnik P, Guggino WB. Cofilin interacts with ClC-5 and regulates albumin uptake in proximal tubule cell lines Journal of Biological Chemistry. 278: 40169-40176. PMID 12904289 DOI: 10.1074/Jbc.M307890200 |
0.509 |
|
| 2003 |
Christensen EI, Devuyst O, Dom G, Nielsen R, Van der Smissen P, Verroust P, Leruth M, Guggino WB, Courtoy PJ. Loss of chloride channel ClC-5 impairs endocytosis by defective trafficking of megalin and cubilin in kidney proximal tubules. Proceedings of the National Academy of Sciences of the United States of America. 100: 8472-7. PMID 12815097 DOI: 10.1073/Pnas.1432873100 |
0.353 |
|
| 2003 |
Nascimento DS, Reis CU, Goldenberg RC, Ortiga-Carvalho TM, Pazos-Moura CC, Guggino SE, Guggino WB, Morales MM. Estrogen modulates ClC-2 chloride channel gene expression in rat kidney. PflüGers Archiv : European Journal of Physiology. 446: 593-9. PMID 12811561 DOI: 10.1007/S00424-003-1095-Y |
0.355 |
|
| 2003 |
Fong P, Argent BE, Guggino WB, Gray MA. Characterization of vectorial chloride transport pathways in the human pancreatic duct adenocarcinoma cell line HPAF. American Journal of Physiology. Cell Physiology. 285: C433-45. PMID 12711595 DOI: 10.1152/Ajpcell.00509.2002 |
0.408 |
|
| 2003 |
Wang SX, Ikeda M, Guggino WB. The cytoplasmic tail of large conductance, voltage- and Ca2+-activated K+ (MaxiK) channel is necessary for its cell surface expression. The Journal of Biological Chemistry. 278: 2713-22. PMID 12438308 DOI: 10.1074/Jbc.M208411200 |
0.412 |
|
| 2002 |
Devuyst O, Guggino WB. Chloride channels in the kidney: lessons learned from knockout animals. American Journal of Physiology. Renal Physiology. 283: F1176-91. PMID 12426234 DOI: 10.1152/Ajprenal.00184.2002 |
0.405 |
|
| 2002 |
Lebeau C, Hanaoka K, Moore-Hoon ML, Guggino WB, Beauwens R, Devuyst O. Basolateral chloride transporters in autosomal dominant polycystic kidney disease. PflüGers Archiv : European Journal of Physiology. 444: 722-31. PMID 12355171 DOI: 10.1007/s00424-002-0880-3 |
0.301 |
|
| 2002 |
Ikeda M, Guggino WB. Do polycystins function as cation channels? Current Opinion in Nephrology and Hypertension. 11: 539-45. PMID 12187319 DOI: 10.1097/00041552-200209000-00010 |
0.33 |
|
| 2002 |
Ikeda M, Beitz E, Kozono D, Guggino WB, Agre P, Yasui M. Characterization of aquaporin-6 as a nitrate channel in mammalian cells. Requirement of pore-lining residue threonine 63. The Journal of Biological Chemistry. 277: 39873-9. PMID 12177001 DOI: 10.1074/Jbc.M207008200 |
0.388 |
|
| 2002 |
Hazama A, Kozono D, Guggino WB, Agre P, Yasui M. Ion permeation of AQP6 water channel protein. Single channel recordings after Hg2+ activation. The Journal of Biological Chemistry. 277: 29224-30. PMID 12034750 DOI: 10.1074/Jbc.M204258200 |
0.353 |
|
| 2002 |
Ornellas DS, Nascimento DS, Christoph DH, Guggino WB, Morales MM. Aldosterone and high-NaCl diet modulate ClC-2 chloride channel gene expression in rat kidney. PflüGers Archiv : European Journal of Physiology. 444: 193-201. PMID 11976932 DOI: 10.1007/S00424-002-0788-Y |
0.373 |
|
| 2002 |
Ketchum CJ, Yue H, Alessi KA, Devidas S, Guggino WB, Maloney PC. Intracellular cysteines of the cystic fibrosis transmembrane conductance regulator (CFTR) modulate channel gating. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 12: 1-8. PMID 11914543 DOI: 10.1159/000047821 |
0.435 |
|
| 2002 |
Schwiebert EM, Wallace DP, Braunstein GM, King SR, Peti-Peterdi J, Hanaoka K, Guggino WB, Guay-Woodford LM, Bell PD, Sullivan LP, Grantham JJ, Taylor AL. Autocrine extracellular purinergic signaling in epithelial cells derived from polycystic kidneys. American Journal of Physiology. Renal Physiology. 282: F763-75. PMID 11880338 DOI: 10.1152/Ajprenal.0337.2000 |
0.391 |
|
| 2002 |
Edmonds RD, Silva IV, Guggino WB, Butler RB, Zeitlin PL, Blaisdell CJ. ClC-5: ontogeny of an alternative chloride channel in respiratory epithelia. American Journal of Physiology. Lung Cellular and Molecular Physiology. 282: L501-7. PMID 11839544 DOI: 10.1152/Ajplung.00207.2001 |
0.375 |
|
| 2002 |
Morales MM, Nascimento DS, Capella MA, Lopes AG, Guggino WB. Arginine vasopressin regulates CFTR and ClC-2 mRNA expression in rat kidney cortex and medulla. Pflugers Archiv : European Journal of Physiology. 443: 202-11. PMID 11713645 DOI: 10.1007/S004240100671 |
0.369 |
|
| 2002 |
Cheng J, Moyer BD, Milewski M, Loffing J, Ikeda M, Mickle JE, Cutting GR, Li M, Stanton BA, Guggino WB. A Golgi-associated PDZ domain protein modulates cystic fibrosis transmembrane regulator plasma membrane expression. The Journal of Biological Chemistry. 277: 3520-9. PMID 11707463 DOI: 10.1074/Jbc.M110177200 |
0.382 |
|
| 2002 |
Boletta A, Qian F, Onuchic LF, Bhunia AK, Phakdeekitcharoen B, Hanaoka K, Guggino W, Monaco L, Germino GG. Polycystin-1, the gene product of PKD1, induces resistance to apoptosis and spontaneous tubulogenesis in MDCK cells. Molecular Cell. 6: 1267-73. PMID 11106764 DOI: 10.1016/S1097-2765(00)00123-4 |
0.348 |
|
| 2001 |
Boyle MP, Enke RA, Adams RJ, Guggino WB, Zeitlin PL. In utero AAV-mediated gene transfer to rabbit pulmonary epithelium. Molecular Therapy : the Journal of the American Society of Gene Therapy. 4: 115-21. PMID 11482982 DOI: 10.1006/Mthe.2001.0428 |
0.333 |
|
| 2001 |
Guggino WB. Cystic fibrosis salt/fluid controversy: in the thick of it. Nature Medicine. 7: 888-9. PMID 11479614 DOI: 10.1038/90914 |
0.319 |
|
| 2001 |
Hanaoka K, Qian F, Boletta A, Bhunia AK, Piontek K, Tsiokas L, Sukhatme VP, Guggino WB, Germino GG. Co-assembly of polycystin-1 and -2 produces unique cation-permeable currents. Nature. 408: 990-4. PMID 11140688 DOI: 10.1038/35050128 |
0.385 |
|
| 2001 |
Hryciw DH, Guggino WB. Cystic fibrosis transmembrane conductance regulator and the outwardly rectifying chloride channel: a relationship between two chloride channels expressed in epithelial cells. Clinical and Experimental Pharmacology & Physiology. 27: 892-5. PMID 11071305 DOI: 10.1046/J.1440-1681.2000.03356.X |
0.421 |
|
| 2000 |
Wang SS, Devuyst O, Courtoy PJ, Wang XT, Wang H, Wang Y, Thakker RV, Guggino S, Guggino WB. Mice lacking renal chloride channel, CLC-5, are a model for Dent's disease, a nephrolithiasis disorder associated with defective receptor-mediated endocytosis. Human Molecular Genetics. 9: 2937-45. PMID 11115837 DOI: 10.1093/Hmg/9.20.2937 |
0.522 |
|
| 2000 |
Wang S, Yue H, Derin RB, Guggino WB, Li M. Accessory protein facilitated CFTR-CFTR interaction, a molecular mechanism to potentiate the chloride channel activity. Cell. 103: 169-79. PMID 11051556 DOI: 10.1016/S0092-8674(00)00096-9 |
0.431 |
|
| 2000 |
Guggino WB, Guggino SE. Amiloride-sensitive sodium channels contribute to the woes of the flu. Proceedings of the National Academy of Sciences of the United States of America. 97: 9827-9. PMID 10963654 DOI: 10.1073/Pnas.97.18.9827 |
0.335 |
|
| 2000 |
Moyer BD, Duhaime M, Shaw C, Denton J, Reynolds D, Karlson KH, Pfeiffer J, Wang S, Mickle JE, Milewski M, Cutting GR, Guggino WB, Li M, Stanton BA. The PDZ-interacting domain of cystic fibrosis transmembrane conductance regulator is required for functional expression in the apical plasma membrane. The Journal of Biological Chemistry. 275: 27069-74. PMID 10852925 DOI: 10.1074/Jbc.M004951200 |
0.373 |
|
| 2000 |
Yue H, Devidas S, Guggino WB. The two halves of CFTR form a dual-pore ion channel. The Journal of Biological Chemistry. 275: 10030-4. PMID 10744680 DOI: 10.1074/Jbc.275.14.10030 |
0.366 |
|
| 2000 |
Silva IV, Blaisdell CJ, Guggino SE, Guggino WB. PTH regulates expression of ClC-5 chloride channel in the kidney. American Journal of Physiology. Renal Physiology. 278: F238-45. PMID 10662728 DOI: 10.1152/Ajprenal.2000.278.2.F238 |
0.305 |
|
| 2000 |
Hanaoka K, Wright JM, Cheglakov IB, Morita T, Guggino WB. A 59 amino acid insertion increases Ca(2+) sensitivity of rbslo1, a Ca2+ -activated K(+) channel in renal epithelia. The Journal of Membrane Biology. 172: 193-201. PMID 10568789 DOI: 10.1007/S002329900596 |
0.333 |
|
| 1999 |
Wagner JA, Messner AH, Moran ML, Daifuku R, Kouyama K, Desch JK, Manley S, Norbash AM, Conrad CK, Friborg S, Reynolds T, Guggino WB, Moss RB, Carter BJ, Wine JJ, et al. Safety and biological efficacy of an adeno-associated virus vector-cystic fibrosis transmembrane regulator (AAV-CFTR) in the cystic fibrosis maxillary sinus. The Laryngoscope. 109: 266-74. PMID 10890777 DOI: 10.1097/00005537-199902000-00017 |
0.304 |
|
| 1999 |
Moyer BD, Denton J, Karlson KH, Reynolds D, Wang S, Mickle JE, Milewski M, Cutting GR, Guggino WB, Li M, Stanton BA. A PDZ-interacting domain in CFTR is an apical membrane polarization signal. The Journal of Clinical Investigation. 104: 1353-61. PMID 10562297 DOI: 10.1172/Jci7453 |
0.399 |
|
| 1999 |
Beck SE, Jones LA, Chesnut K, Walsh SM, Reynolds TC, Carter BJ, Askin FB, Flotte TR, Guggino WB. Repeated delivery of adeno-associated virus vectors to the rabbit airway. Journal of Virology. 73: 9446-55. PMID 10516053 DOI: 10.1128/Jvi.73.11.9446-9455.1999 |
0.315 |
|
| 1999 |
Guggino WB. Cystic fibrosis and the salt controversy. Cell. 96: 607-10. PMID 10089875 DOI: 10.1016/S0092-8674(00)80570-X |
0.324 |
|
| 1999 |
Schwiebert EM, Benos DJ, Egan ME, Stutts MJ, Guggino WB. CFTR is a conductance regulator as well as a chloride channel. Physiological Reviews. 79: S145-66. PMID 9922379 DOI: 10.1152/Physrev.1999.79.1.S145 |
0.387 |
|
| 1998 |
Guggino WB. Focus on "Exocytosis is not involved in activation of Clsecretion via CFTR in Calu-3 airway epithelial cells". American Journal of Physiology. Cell Physiology. 275: C911-C912. PMID 29585297 DOI: 10.1152/Ajpcell.1998.275.4.C911 |
0.399 |
|
| 1998 |
Taylor AL, Kudlow BA, Marrs KL, Gruenert DC, Guggino WB, Schwiebert EM. Bioluminescence detection of ATP release mechanisms in epithelia. The American Journal of Physiology. 275: C1391-406. PMID 9814989 DOI: 10.1152/Ajpcell.1998.275.5.C1391 |
0.325 |
|
| 1998 |
Jiang Q, Mak D, Devidas S, Schwiebert EM, Bragin A, Zhang Y, Skach WR, Guggino WB, Foskett JK, Engelhardt JF. Cystic fibrosis transmembrane conductance regulator-associated ATP release is controlled by a chloride sensor. The Journal of Cell Biology. 143: 645-57. PMID 9813087 DOI: 10.1083/Jcb.143.3.645 |
0.403 |
|
| 1998 |
Devidas S, Yue H, Guggino WB. The second half of the cystic fibrosis transmembrane conductance regulator forms a functional chloride channel. The Journal of Biological Chemistry. 273: 29373-80. PMID 9792638 DOI: 10.1074/Jbc.273.45.29373 |
0.371 |
|
| 1998 |
Tsukaguchi H, Shayakul C, Berger UV, Mackenzie B, Devidas S, Guggino WB, van Hoek AN, Hediger MA. Molecular characterization of a broad selectivity neutral solute channel. The Journal of Biological Chemistry. 273: 24737-43. PMID 9733774 DOI: 10.1074/Jbc.273.38.24737 |
0.318 |
|
| 1998 |
Schwiebert EM, Egan ME, Guggino WB. Assays of dynamics, mechanisms, and regulation of ATP transport and release: implications for study of ABC transporter function. Methods in Enzymology. 292: 664-75. PMID 9711590 DOI: 10.1016/S0076-6879(98)92051-1 |
0.326 |
|
| 1998 |
Moyer BD, Loffing J, Schwiebert EM, Loffing-Cueni D, Halpin PA, Karlson KH, Ismailov II, Guggino WB, Langford GM, Stanton BA. Membrane trafficking of the cystic fibrosis gene product, cystic fibrosis transmembrane conductance regulator, tagged with green fluorescent protein in Madin-Darby canine kidney cells Journal of Biological Chemistry. 273: 21759-21768. PMID 9705313 DOI: 10.1074/Jbc.273.34.21759 |
0.408 |
|
| 1998 |
Wang S, Raab RW, Schatz PJ, Guggino WB, Li M. Peptide binding consensus of the NHE-RF-PDZ1 domain matches the C-terminal sequence of cystic fibrosis transmembrane conductance regulator (CFTR). Febs Letters. 427: 103-8. PMID 9613608 DOI: 10.1016/S0014-5793(98)00402-5 |
0.338 |
|
| 1998 |
Schwiebert EM, Cid-Soto LP, Stafford D, Carter M, Blaisdell CJ, Zeitlin PL, Guggino WB, Cutting GR. Analysis of ClC-2 channels as an alternative pathway for chloride conduction in cystic fibrosis airway cells. Proceedings of the National Academy of Sciences of the United States of America. 95: 3879-84. PMID 9520461 DOI: 10.1073/Pnas.95.7.3879 |
0.408 |
|
| 1998 |
Mickle JE, Macek M, Fulmer-Smentek SB, Egan MM, Schwiebert E, Guggino W, Moss R, Cutting GR. A mutation in the cystic fibrosis transmembrane conductance regulator gene associated with elevated sweat chloride concentrations in the absence of cystic fibrosis. Human Molecular Genetics. 7: 729-35. PMID 9499426 DOI: 10.1093/Hmg/7.4.729 |
0.401 |
|
| 1998 |
Woo JS, Inoue CN, Hanaoka K, Schwiebert EM, Guggino SE, Guggino WB. Adenylyl cyclase is involved in desensitization and recovery of ATP-stimulated Cl- secretion in MDCK cells. The American Journal of Physiology. 274: C371-8. PMID 9486126 DOI: 10.1152/Ajpcell.1998.274.2.C371 |
0.333 |
|
| 1998 |
Schwiebert EM, Morales MM, Devidas S, Egan ME, Guggino WB. Chloride channel and chloride conductance regulator domains of CFTR, the cystic fibrosis transmembrane conductance regulator. Proceedings of the National Academy of Sciences of the United States of America. 95: 2674-9. PMID 9482946 DOI: 10.1073/Pnas.95.5.2674 |
0.431 |
|
| 1997 |
McNicholas CM, Nason MW, Guggino WB, Schwiebert EM, Hebert SC, Giebisch G, Egan ME. A functional CFTR-NBF1 is required for ROMK2-CFTR interaction. American Journal of Physiology. Renal Physiology. 273: F843-F848. PMID 29587108 DOI: 10.1152/ajprenal.1997.273.5.F843 |
0.301 |
|
| 1997 |
Morita T, Hanaoka K, Morales MM, Montrose-Rafizadeh C, Guggino WB. Cloning and characterization of maxi Kchannel α-subunit in rabbit kidney. American Journal of Physiology. Renal Physiology. 273: F615-F624. PMID 29587095 DOI: 10.1152/Ajprenal.1997.273.4.F615 |
0.336 |
|
| 1997 |
McNicholas CM, Nason MW, Guggino WB, Schwiebert EM, Hebert SC, Giebisch G, Egan ME. A functional CFTR-NBF1 is required for ROMK2-CFTR interaction. The American Journal of Physiology. 273: F843-8. PMID 9374850 DOI: 10.1152/Ajprenal.1997.273.5.F843 |
0.394 |
|
| 1997 |
Rubenstein RC, McVeigh U, Flotte TR, Guggino WB, Zeitlin PL. CFTR gene transduction in neonatal rabbits using an adeno-associated virus (AAV) vector. Gene Therapy. 4: 384-92. PMID 9274714 DOI: 10.1038/Sj.Gt.3300417 |
0.336 |
|
| 1997 |
Devidas S, Guggino WB. The cystic fibrosis transmembrane conductance regulator and ATP. Current Opinion in Cell Biology. 9: 547-52. PMID 9261051 DOI: 10.1016/S0955-0674(97)80032-4 |
0.384 |
|
| 1997 |
Inoue CN, Woo JS, Schwiebert EM, Morita T, Hanaoka K, Guggino SE, Guggino WB. Role of purinergic receptors in chloride secretion in Caco-2 cells. The American Journal of Physiology. 272: C1862-70. PMID 9227415 DOI: 10.1152/Ajpcell.1997.272.6.C1862 |
0.36 |
|
| 1997 |
Xu XZ, Li HS, Guggino WB, Montell C. Coassembly of TRP and TRPL produces a distinct store-operated conductance. Cell. 89: 1155-64. PMID 9215637 DOI: 10.1016/S0092-8674(00)80302-5 |
0.328 |
|
| 1997 |
Devuyst O, Golstein PE, Sanches MV, Piontek K, Wilson PD, Guggino WB, Dumont JE, Beauwens R. Expression of CFTR in human and bovine thyroid epithelium. The American Journal of Physiology. 272: C1299-308. PMID 9142856 DOI: 10.1152/Ajpcell.1997.272.4.C1299 |
0.389 |
|
| 1997 |
Schwiebert EM, Potter ED, Hwang TH, Woo JS, Ding C, Qiu W, Guggino WB, Levine MA, Guggino SE. CGMP stimulates sodium and chloride currents in rat tracheal airway epithelia American Journal of Physiology - Cell Physiology. 272: C911-C922. PMID 9124527 DOI: 10.1152/Ajpcell.1997.272.3.C911 |
0.384 |
|
| 1997 |
Mogayzel PJ, Henning KA, Bittner ML, Novotny EA, Schwiebert EM, Guggino WB, Jiang Y, Rosenfeld MA. Functional human CFTR produced by stable Chinese hamster ovary cell lines derived using yeast artificial chromosomes. Human Molecular Genetics. 6: 59-68. PMID 9002671 DOI: 10.1093/Hmg/6.1.59 |
0.392 |
|
| 1996 |
Devuyst O, Burrow CR, Schwiebert EM, Guggino WB, Wilson PD. Developmental regulation of CFTR expression during human nephrogenesis. The American Journal of Physiology. 271: F723-35. PMID 8853436 DOI: 10.1152/Ajprenal.1996.271.3.F723 |
0.386 |
|
| 1996 |
Hanaoka K, Devuyst O, Schwiebert EM, Wilson PD, Guggino WB. A role for CFTR in human autosomal dominant polycystic kidney disease. The American Journal of Physiology. 270: C389-99. PMID 8772467 DOI: 10.1152/Ajpcell.1996.270.1.C389 |
0.401 |
|
| 1996 |
Morales MM, Carroll TP, Morita T, Schwiebert EM, Devuyst O, Wilson PD, Lopes AG, Stanton BA, Dietz HC, Cutting GR, Guggino WB. Both the wild type and a functional isoform of CFTR are expressed in kidney. The American Journal of Physiology. 270: F1038-48. PMID 8764323 DOI: 10.1152/Ajprenal.1996.270.6.F1038 |
0.425 |
|
| 1996 |
Hwang TH, Schwiebert EM, Guggino WB. Apical and basolateral ATP stimulates tracheal epithelial chloride secretion via multiple purinergic receptors American Journal of Physiology - Cell Physiology. 270: C1611-C1623. PMID 8764143 DOI: 10.1152/Ajpcell.1996.270.6.C1611 |
0.397 |
|
| 1996 |
McNicholas CM, Guggino WB, Schwiebert EM, Hebert SC, Giebisch G, Egan ME. Sensitivity of a renal K+ channel (ROMK2) to the inhibitory sulfonylurea compound glibenclamide is enhanced by coexpression with the ATP-binding cassette transporter cystic fibrosis transmembrane regulator. Proceedings of the National Academy of Sciences of the United States of America. 93: 8083-8. PMID 8755607 DOI: 10.1073/Pnas.93.15.8083 |
0.405 |
|
| 1996 |
Calamita G, Bishai WR, Preston GM, Guggino WB, Agre P. Molecular cloning and characterization of AqpZ, a water channel from Escherichia coli. The Journal of Biological Chemistry. 270: 29063-6. PMID 7493926 DOI: 10.1074/Jbc.270.49.29063 |
0.328 |
|
| 1995 |
Cid LP, Montrose-Rafizadeh C, Smith DI, Guggino WB, Cutting GR. Cloning of a putative human voltage-gated chloride channel (CIC-2) cDNA widely expressed in human tissues. Human Molecular Genetics. 4: 407-13. PMID 7795595 DOI: 10.1093/Hmg/4.3.407 |
0.361 |
|
| 1995 |
Bredt DS, Wang TL, Cohen NA, Guggino WB, Snyder SH. Cloning and expression of two brain-specific inwardly rectifying potassium channels. Proceedings of the National Academy of Sciences of the United States of America. 92: 6753-7. PMID 7624316 DOI: 10.1073/Pnas.92.15.6753 |
0.324 |
|
| 1995 |
Fulmer SB, Schwiebert EM, Morales MM, Guggino WB, Cutting GR. Two cystic fibrosis transmembrane conductance regulator mutations have different effects on both pulmonary phenotype and regulation of outwardly rectified chloride currents. Proceedings of the National Academy of Sciences of the United States of America. 92: 6832-6. PMID 7542778 DOI: 10.1073/Pnas.92.15.6832 |
0.433 |
|
| 1995 |
Schwiebert EM, Egan ME, Hwang TH, Fulmer SB, Allen SS, Cutting GR, Guggino WB. CFTR regulates outwardly rectifying chloride channels through an autocrine mechanism involving ATP. Cell. 81: 1063-73. PMID 7541313 DOI: 10.1016/S0092-8674(05)80011-X |
0.432 |
|
| 1995 |
Carroll TP, Morales MM, Fulmer SB, Allen SS, Flotte TR, Cutting GR, Guggino WB. Alternate translation initiation codons can create functional forms of cystic fibrosis transmembrane conductance regulator. The Journal of Biological Chemistry. 270: 11941-6. PMID 7538127 DOI: 10.1074/Jbc.270.20.11941 |
0.385 |
|
| 1995 |
Mulders SM, Preston GM, Deen PMT, Guggino WB, Van Os CH, Agre P. Water channel properties of major intrinsic protein of lens Journal of Biological Chemistry. 270: 9010-9016. PMID 7536742 DOI: 10.1074/Jbc.270.15.9010 |
0.372 |
|
| 1995 |
Egan ME, Schwiebert EM, Guggino WB. Differential expression of ORCC and CFTR induced by low temperature in CF airway epithelial cells. The American Journal of Physiology. 268: C243-51. PMID 7530908 DOI: 10.1152/Ajpcell.1995.268.1.C243 |
0.336 |
|
| 1995 |
Raina S, Preston GM, Guggino WB, Agre P. Molecular cloning and characterization of an aquaporin cDNA from salivary, lacrimal, and respiratory tissues. The Journal of Biological Chemistry. 270: 1908-12. PMID 7530250 DOI: 10.1074/Jbc.270.4.1908 |
0.337 |
|
| 1994 |
Jung JS, Bhat RV, Preston GM, Guggino WB, Baraban JM, Agre P. Molecular characterization of an aquaporin cDNA from brain: candidate osmoreceptor and regulator of water balance. Proceedings of the National Academy of Sciences of the United States of America. 91: 13052-6. PMID 7528931 DOI: 10.1073/Pnas.91.26.13052 |
0.33 |
|
| 1994 |
Schwiebert EM, Flotte T, Cutting GR, Guggino WB. Both CFTR and outwardly rectifying chloride channels contribute to cAMP- stimulated whole cell chloride currents American Journal of Physiology - Cell Physiology. 266. PMID 7515570 DOI: 10.1152/Ajpcell.1994.266.5.C1464 |
0.427 |
|
| 1994 |
Rao MC, Bissonnette GB, Mahaffey T, Guggino WB, Goldstein JL. Rectal epithelial expression of protein kinase A phosphorylation of cystic fibrosis transmembrane conductance regulator. Gastroenterology. 106: 890-8. PMID 7511554 DOI: 10.1016/0016-5085(94)90747-1 |
0.344 |
|
| 1994 |
Carroll TP, McIntosh I, Egan ME, Zeitlin PL, Cutting GR, Guggino WB. Transmembrane mutations alter the channel characteristics of the cystic fibrosis transmembrane conductance regulator expressed in Xenopus oocytes Cellular Physiology and Biochemistry. 4: 10-18. DOI: 10.1159/000154705 |
0.365 |
|
| 1994 |
Schwiebert EM, Lopes AG, Guggino WB. Chapter 10 Chloride Channels along the Nephron Current Topics in Membranes. 42: 265-315. DOI: 10.1016/S0070-2161(08)60825-4 |
0.37 |
|
| 1993 |
Lu L, Yang T, Markakis D, Guggino WB, Craig RW. Alterations in a voltage-gated K+ current during the differentiation of ML-1 human myeloblastic leukemia cells. The Journal of Membrane Biology. 132: 267-74. PMID 8492309 DOI: 10.1007/Bf00235743 |
0.309 |
|
| 1993 |
Agre P, Preston GM, Smith BL, Jung JS, Raina S, Moon C, Guggino WB, Nielsen S. Aquaporin CHIP: the archetypal molecular water channel. The American Journal of Physiology. 265: F463-76. PMID 7694481 DOI: 10.1152/Ajprenal.1993.265.4.F463 |
0.319 |
|
| 1993 |
Lu L, Markakis D, Guggino WB. Identification and regulation of whole-cell Cl- and Ca(2+)-activated K+ currents in cultured medullary thick ascending limb cells. The Journal of Membrane Biology. 135: 181-9. PMID 7692066 DOI: 10.1007/Bf00231443 |
0.342 |
|
| 1993 |
Guggino WB. Outwardly rectifying chloride channels and CF: a divorce and remarriage. Journal of Bioenergetics and Biomembranes. 25: 27-35. PMID 7680029 DOI: 10.1007/Bf00768065 |
0.388 |
|
| 1993 |
Flotte TR, Afione SA, Conrad C, McGrath SA, Solow R, Oka H, Zeitlin PL, Guggino WB, Carter BJ. Stable in vivo expression of the cystic fibrosis transmembrane conductance regulator with an adeno-associated virus vector. Proceedings of the National Academy of Sciences of the United States of America. 90: 10613-7. PMID 7504271 DOI: 10.1073/Pnas.90.22.10613 |
0.351 |
|
| 1993 |
Carroll TP, Schwiebert EM, Guggino WB. CFTR: Structure and Function Cellular Physiology and Biochemistry. 3: 388-399. DOI: 10.1159/000154700 |
0.311 |
|
| 1992 |
Egan M, Flotte T, Afione S, Solow R, Zeitlin PL, Carter BJ, Guggino WB. Defective regulation of outwardly rectifying Cl- channels by protein kinase a corrected by insertion of CFTR Nature. 358: 581-584. PMID 1380129 DOI: 10.1038/358581A0 |
0.43 |
|
| 1992 |
Preston GM, Carroll TP, Guggino WB, Agre P. Appearance of water channels in Xenopus oocytes expressing red cell CHIP28 protein. Science (New York, N.Y.). 256: 385-7. PMID 1373524 DOI: 10.1126/Science.256.5055.385 |
0.347 |
|
| 1992 |
Bargon J, Trapnell BC, Chu CS, Rosenthal ER, Yoshimura K, Guggino WB, Dalemans W, Pavirani A, Lecocq JP, Crystal RG. Down-regulation of cystic fibrosis transmembrane conductance regulator gene expression by agents that modulate intracellular divalent cations. Molecular and Cellular Biology. 12: 1872-8. PMID 1372390 DOI: 10.1128/Mcb.12.4.1872 |
0.411 |
|
| 1992 |
Hwang TC, Egan ME, Guggino WB. Kinetic interaction of fatty acids with outwardly rectifying chloride channels Cellular Physiology and Biochemistry. 2: 308-315. DOI: 10.1159/000154653 |
0.354 |
|
| 1991 |
Montrose-Rafizadeh C, Guggino WB. Role of intracellular calcium in volume regulation by rabbit medullary thick ascending limb cells. The American Journal of Physiology. 260: F402-9. PMID 1900390 DOI: 10.1152/Ajprenal.1991.260.3.F402 |
0.334 |
|
| 1991 |
Hwang TC, Guggino WB. Regulation of epithelial chloride channels: roles of protein kinases and arachidonic acid. Advances in Experimental Medicine and Biology. 290: 209-23; discussion 2. PMID 1719759 DOI: 10.1007/978-1-4684-5934-0_21 |
0.348 |
|
| 1991 |
Crawford I, Maloney PC, Zeitlin PL, Guggino WB, Hyde SC, Turley H, Gatter KC, Harris A, Higgins CF. Immunocytochemical localization of the cystic fibrosis gene product CFTR Proceedings of the National Academy of Sciences of the United States of America. 88: 9262-9266. PMID 1718002 DOI: 10.1073/Pnas.88.20.9262 |
0.426 |
|
| 1991 |
Lu L, Markakis D, Guggino WB. Blockade of Ca2+-Dependent Cl– Current in Xenopus Oocytes by C– Channel Blockers and Antimalarial Drugs Cellular Physiology and Biochemistry. 1: 251-262. DOI: 10.1159/000154613 |
0.34 |
|
| 1990 |
Montrose-Rafizadeh C, Guggino WB. Cell volume regulation in the nephron. Annual Review of Physiology. 52: 761-72. PMID 2158770 DOI: 10.1146/Annurev.Ph.52.030190.003553 |
0.357 |
|
| 1990 |
Guggino WB. In Reply: Chloride Channels in Cystic Fibrosis Patients Science. 247: 222-222. DOI: 10.1126/Science.247.4939.222-A |
0.342 |
|
| 1989 |
Cornejo M, Guggino SE, Guggino WB. Ca2+-activated K+ channels from cultured renal medullary thick ascending limb cells: effects of pH. The Journal of Membrane Biology. 110: 49-55. PMID 2795640 DOI: 10.1007/Bf01870992 |
0.348 |
|
| 1989 |
Taniguchi J, Guggino WB. Membrane stretch: a physiological stimulator of Ca2+-activated K+ channels in thick ascending limb. The American Journal of Physiology. 257: F347-52. PMID 2782419 DOI: 10.1152/Ajprenal.1989.257.3.F347 |
0.345 |
|
| 1989 |
Lu L, Zeitlin PL, Guggino WB, Craig RW. Gene transfer by lipofection in rabbit and human secretory epithelial cells PflüGers Archiv European Journal of Physiology. 415: 198-203. PMID 2594476 DOI: 10.1007/Bf00370592 |
0.32 |
|
| 1989 |
Hwang TC, Lu L, Zeitlin PL, Gruenert DC, Huganir R, Guggino WB. C1- channels in CF: Lack of activation by protein kinase C and cAMP-dependent protein kinase Science. 244: 1351-1353. PMID 2472005 DOI: 10.1126/Science.2472005 |
0.391 |
|
| 1988 |
Lopes AG, Guggino WB. Volume regulation in the early proximal tubule of the Necturus kidney. The Journal of Membrane Biology. 97: 117-25. PMID 3446818 DOI: 10.1007/Bf01869418 |
0.33 |
|
| 1988 |
Lopes AG, Amzel LM, Markakis D, Guggino WB. Cell volume regulation by the thin descending limb of Henle's loop Proceedings of the National Academy of Sciences of the United States of America. 85: 2873-2877. PMID 2833759 DOI: 10.1073/Pnas.85.8.2873 |
0.334 |
|
| 1985 |
Guggino WB, Oberleithner H, Giebisch G. Relationship between cell volume and ion transport in the early distal tubule of the Amphiuma kidney. The Journal of General Physiology. 86: 31-58. PMID 2411847 DOI: 10.1085/Jgp.86.1.31 |
0.328 |
|
| 1983 |
Oberleithner H, Ritter M, Lang F, Guggino W. Anthracene-9-carboxylic acid inhibits renal chloride reabsorption. Pflugers Archiv : European Journal of Physiology. 398: 172-4. PMID 6604902 DOI: 10.1007/Bf00581068 |
0.327 |
|
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