| Year |
Citation |
Score |
| 2023 |
Blanch-Lombarte O, Ouchi D, Jimenez-Moyano E, Carabelli J, Marin MA, Peña R, Pelletier A, Talla A, Sharma A, Dalmau J, Santos JR, Sékaly RP, Clotet B, Prado JG. Selective loss of CD107a TIGIT+ memory HIV-1-specific CD8+ T cells in PLWH over a decade of ART. Elife. 12. PMID 37723971 DOI: 10.7554/eLife.83737 |
0.393 |
|
| 2023 |
Mutascio S, Mota T, Franchitti L, Sharma AA, Willemse A, Bergstresser SN, Wang H, Statzu M, Tharp GK, Weiler J, Sékaly RP, Bosinger SE, Paiardini M, Silvestri G, Jones RB, et al. CD8 T cells promote HIV latency by remodeling CD4 T cell metabolism to enhance their survival, quiescence, and stemness. Immunity. PMID 37030290 DOI: 10.1016/j.immuni.2023.03.010 |
0.422 |
|
| 2022 |
Ferrari B, Da Silva AC, Liu KH, Saidakova EV, Korolevskaya LB, Shmagel KV, Shive C, Pacheco Sanchez G, Retuerto M, Sharma AA, Ghneim K, Noel-Romas L, Rodriguez B, Ghannoum MA, Hunt PP, ... ... Sekaly RP, et al. Gut-derived bacterial toxins impair memory CD4 T-cell mitochondrialfunction in HIV-1infection. The Journal of Clinical Investigation. PMID 35316209 DOI: 10.1172/JCI149571 |
0.372 |
|
| 2022 |
Rahman SA, Billinglsley J, Sharma AA, Styles TM, Govindaraj S, Shanmugasundaram U, Babu H, Ribeiro SP, Ali SA, Tharp GK, Ibegbu C, Waggoner S, Johnson RP, Sékaly RP, Villinger F, et al. Lymph node CXCR5+ NK cells associate with control of chronic SHIV infection. Jci Insight. PMID 35271506 DOI: 10.1172/jci.insight.155601 |
0.314 |
|
| 2022 |
Harper J, Ribeiro SP, Chan CN, Aid M, Deleage C, Micci L, Pino M, Cervasi B, Raghunathan G, Rimmer E, Ayanoglu G, Wu G, Shenvi N, Barnard RJ, Del Prete GQ, ... ... Sekaly RP, et al. Interleukin-10 contributes to reservoir establishment and persistence in SIV-infected macaques treated with antiretroviral therapy. The Journal of Clinical Investigation. PMID 35230978 DOI: 10.1172/JCI155251 |
0.311 |
|
| 2021 |
Tomalka JA, Pelletier AN, Fourati S, Latif MB, Sharma A, Furr K, Carlson K, Lifton M, Gonzalez A, Wilkinson P, Franchini G, Parks R, Letvin N, Yates N, Seaton K, ... Sekaly RP, et al. The transcription factor CREB1 is a mechanistic driver of immunogenicity and reduced HIV-1 acquisition following ALVAC vaccination. Nature Immunology. PMID 34556879 DOI: 10.1038/s41590-021-01026-9 |
0.333 |
|
| 2021 |
Pino M, Pereira Ribeiro S, Pagliuzza A, Ghneim K, Khan A, Ryan E, Harper JL, King CT, Welbourn S, Micci L, Aldrete S, Delman KA, Stuart T, Lowe M, Brenchley JM, ... ... Sekaly RP, et al. Increased homeostatic cytokines and stability of HIV-infected memory CD4 T-cells identify individuals with suboptimal CD4 T-cell recovery on-ART. Plos Pathogens. 17: e1009825. PMID 34449812 DOI: 10.1371/journal.ppat.1009825 |
0.41 |
|
| 2021 |
Nganou-Makamdop K, Talla A, Sharma AA, Darko S, Ransier A, Laboune F, Chipman JG, Beilman GJ, Hoskuldsson T, Fourati S, Schmidt TE, Arumugam S, Lima NS, Moon D, Callisto S, ... ... Sekaly RP, et al. Translocated microbiome composition determines immunological outcome in treated HIV infection. Cell. PMID 34237254 DOI: 10.1016/j.cell.2021.05.023 |
0.349 |
|
| 2021 |
Shukla S, Kumari S, Bal SK, Monaco DC, Ribeiro SP, Sekaly RP, Sharma AA. "Go", "No Go," or "Where to Go"; does microbiota dictate T cell exhaustion, programming, and HIV persistence? Current Opinion in Hiv and Aids. 16: 215-222. PMID 34039845 DOI: 10.1097/COH.0000000000000692 |
0.383 |
|
| 2021 |
Razzaghian HR, Sharafian Z, Sharma AA, Boyce GK, Lee K, Da Silva R, Orban PC, Sekaly RP, Ross CJ, Lavoie PM. Neonatal T Helper 17 Responses Are Skewed Towards an Immunoregulatory Interleukin-22 Phenotype. Frontiers in Immunology. 12: 655027. PMID 34012439 DOI: 10.3389/fimmu.2021.655027 |
0.314 |
|
| 2021 |
Guo H, Wang Q, Ghneim K, Wang L, Rampanelli E, Holley-Guthrie E, Cheng L, Garrido C, Margolis DM, Eller LA, Robb ML, Sekaly RP, Chen X, Su L, Ting JP. Multi-omics analyses reveal that HIV-1 alters CD4 T cell immunometabolism to fuel virus replication. Nature Immunology. PMID 33767427 DOI: 10.1038/s41590-021-00898-1 |
0.387 |
|
| 2021 |
Zhang C, Song JW, Huang HH, Fan X, Huang L, Deng JN, Tu B, Wang K, Li J, Zhou MJ, Yang CX, Zhao QW, Yang T, Wang LF, Zhang JY, et al. NLRP3 inflammasome induces CD4+ T cell loss in chronically HIV-1-infected patients. The Journal of Clinical Investigation. 131. PMID 33720048 DOI: 10.1172/JCI138861 |
0.413 |
|
| 2020 |
Rutishauser RL, Deguit CDT, Hiatt J, Blaeschke F, Roth TL, Wang L, Raymond KA, Starke CE, Mudd JC, Chen W, Smullin CP, Matus-Nicodemos R, Hoh R, Krone MR, Hecht FM, et al. TCF-1 regulates HIV-specific CD8+ T cell expansion capacity. Jci Insight. PMID 33351785 DOI: 10.1172/jci.insight.136648 |
0.416 |
|
| 2020 |
Jackson Z, Roe A, Sharma AA, Lopes FBTP, Talla A, Kleinsorge-Block S, Zamborsky K, Schiavone J, Manjappa S, Schauner R, Lee G, Liu R, Caimi PF, Xiong Y, Krueger W, ... ... Sekaly RP, et al. Automated Manufacture of Autologous CD19 CAR-T Cells for Treatment of Non-hodgkin Lymphoma. Frontiers in Immunology. 11: 1941. PMID 32849651 DOI: 10.3389/Fimmu.2020.01941 |
0.446 |
|
| 2020 |
Buttó LF, Pelletier A, More SK, Zhao N, Osme A, Hager CL, Ghannoum MA, Sekaly RP, Cominelli F, Dave M. Intestinal Stem Cell Niche Defects Result in Impaired 3D Organoid Formation in Mouse Models of Crohn's Disease-like Ileitis. Stem Cell Reports. PMID 32679063 DOI: 10.1016/J.Stemcr.2020.06.017 |
0.309 |
|
| 2020 |
Abdelsamed HA, Zebley CC, Nguyen H, Rutishauser RL, Fan Y, Ghoneim HE, Crawford JC, Alfei F, Alli S, Ribeiro SP, Castellaw AH, McGargill MA, Jin H, Boi SK, Speake C, ... ... Sekaly RP, et al. Beta cell-specific CD8 T cells maintain stem cell memory-associated epigenetic programs during type 1 diabetes. Nature Immunology. PMID 32231298 DOI: 10.1038/S41590-020-0633-5 |
0.427 |
|
| 2020 |
Murray SM, Zhang Y, Douek DC, Sekaly RP. Myeloid Cells Enriched for a Dendritic Cell Population From People Living With HIV Have Altered Gene Expression Not Restored by Antiretroviral Therapy. Frontiers in Immunology. 11: 261. PMID 32194550 DOI: 10.3389/Fimmu.2020.00261 |
0.395 |
|
| 2020 |
Gorini G, Fourati S, Vaccari M, Rahman MA, Gordon SN, Brown DR, Law L, Chang J, Green R, Barrenäs F, Liyanage NPM, Doster MN, Schifanella L, Bissa M, Silva de Castro I, ... ... Sekaly RP, et al. Engagement of monocytes, NK cells, and CD4+ Th1 cells by ALVAC-SIV vaccination results in a decreased risk of SIVmac251 vaginal acquisition. Plos Pathogens. 16: e1008377. PMID 32163525 DOI: 10.1371/Journal.Ppat.1008377 |
0.342 |
|
| 2020 |
Van der Sluis RM, Kumar NA, Pascoe RD, Zerbato JM, Evans VA, Dantanarayana AI, Anderson JL, Sékaly RP, Fromentin R, Chomont N, Cameron PU, Lewin SR. Combination Immune Checkpoint Blockade to Reverse HIV Latency. Journal of Immunology (Baltimore, Md. : 1950). PMID 31988180 DOI: 10.4049/Jimmunol.1901191 |
0.359 |
|
| 2020 |
Caimi P, Reese JS, Otegbeye F, Schneider D, Bakalarz KL, Boughan KM, Cooper B, Galloway E, Gallogly M, Kruger W, Worden A, Kadan M, Lopes FBTP, Sharma A, Malek E, ... ... Sekaly R, et al. On Site Manufacture of AntiCD19 CAR-T Cells. Responses in Subjects with Rapidly Progressive Refractory Lymphomas. Biology of Blood and Marrow Transplantation. 26. DOI: 10.1016/J.Bbmt.2019.12.478 |
0.374 |
|
| 2020 |
Ahmed N, Caimi P, Reese JS, Otegbeye F, Patel S, Schneider D, Boughan KM, Cooper B, Gallogly M, Kruger W, Worden A, Kadan M, Lopes FBTP, Sharma A, Malek E, ... ... Sekaly R, et al. Prophylactic Tocilizumab in Patients with Relapsed Refractory Lymphoma Treated with Anti CD19 Chimeric Antigen Receptor T-Cell Therapy Biology of Blood and Marrow Transplantation. 26. DOI: 10.1016/J.Bbmt.2019.12.447 |
0.39 |
|
| 2019 |
Ojo EO, Sharma AA, Liu R, Moreton S, Checkley-Luttge MA, Gupta K, Lee G, Lee DA, Otegbeye F, Sekaly RP, de Lima M, Wald DN. Membrane bound IL-21 based NK cell feeder cells drive robust expansion and metabolic activation of NK cells. Scientific Reports. 9: 14916. PMID 31624330 DOI: 10.1038/S41598-019-51287-6 |
0.348 |
|
| 2019 |
Kulpa DA, Talla A, Brehm JH, Ribeiro SP, Yuan S, Bebin-Blackwell AG, Miller M, Barnard R, Deeks SG, Hazuda D, Chomont N, Sékaly RP. Differentiation to an effector memory phenotype potentiates HIV-l latency reversal in CD4+ T cells. Journal of Virology. PMID 31578289 DOI: 10.1128/Jvi.00969-19 |
0.499 |
|
| 2019 |
Vaccari M, Fourati S, Brown DR, Silva de Castro I, Bissa M, Schifanella L, Doster MN, Foulds KE, Roederer M, Koup RA, Sui Y, Berzofsky JA, Sekaly RP, Franchini G. Myeloid Cell Crosstalk Regulates the Efficacy of the DNA/ALVAC/gp120 HIV Vaccine Candidate. Frontiers in Immunology. 10: 1072. PMID 31139193 DOI: 10.3389/Fimmu.2019.01072 |
0.429 |
|
| 2019 |
Fourati S, Ribeiro SP, Blasco Tavares Pereira Lopes F, Talla A, Lefebvre F, Cameron M, Kaewkungwal J, Pitisuttithum P, Nitayaphan S, Rerks-Ngarm S, Kim JH, Thomas R, Gilbert PB, Tomaras GD, Koup RA, et al. Integrated systems approach defines the antiviral pathways conferring protection by the RV144 HIV vaccine. Nature Communications. 10: 863. PMID 30787294 DOI: 10.1038/S41467-019-08854-2 |
0.385 |
|
| 2019 |
Fromentin R, DaFonseca S, Costiniuk CT, El-Far M, Procopio FA, Hecht FM, Hoh R, Deeks SG, Hazuda DJ, Lewin SR, Routy J, Sékaly R, Chomont N. PD-1 blockade potentiates HIV latency reversal ex vivo in CD4+ T cells from ART-suppressed individuals. Nature Communications. 10: 814-814. PMID 30778080 DOI: 10.1038/S41467-019-08798-7 |
0.469 |
|
| 2019 |
Caimi PF, Reese J, Otegbeye F, Schneider D, Chamoun K, Boughan KM, Cooper BW, Galloway E, Gallogly M, Kruger W, Worden A, Kadan M, Malek E, Metheny LL, Tomlinson BK, ... Sekaly R, et al. Phase 1 trial of anti-CD19 chimeric antigen receptor T (CAR-T) cells with tumor necrosis alfa receptor superfamily 19 (TNFRSF19) transmembrane domain. Journal of Clinical Oncology. 37: 2539-2539. DOI: 10.1200/Jco.2019.37.15_Suppl.2539 |
0.377 |
|
| 2019 |
Caimi PF, Reese J, Otegbeye F, Schneider D, Bakalarz K, Boughan KM, Cooper B, Gallogly MM, Galloway E, Kruger W, Worden A, Kadan M, Lopes FB, Sharma A, Malek E, ... ... Sekaly R, et al. Phase 1 Study of on Site Manufactured Anti-CD19 CAR-T Cells: Responses in Subjects with Rapidly Progressive Refractory Lymphomas Blood. 134: 4074-4074. DOI: 10.1182/Blood-2019-131300 |
0.382 |
|
| 2019 |
Buttò LF, Pelletier A, Zhao N, Osme A, Hager C, Ghannoum M, Sekaly R, Cominelli F, Dave M. P126 Multiple Signaling Pathway Defects In The Intestinal Stem Cell Niche Likely Trigger Cd-Like Ileitis In Samp1/Yitfc Mice Gastroenterology. 156. DOI: 10.1053/J.Gastro.2019.01.202 |
0.308 |
|
| 2019 |
Jurdi NE, Filali-Mouhim A, Salem I, Retuerto M, Dambrosio NM, Lazarus HM, Caimi P, Cooper B, Tomlinson B, Metheny L, Malek E, Otegbeye F, Sekaly R, Ghannoum M, Lima Md. Transplant Outcomes and Toxicities Are Associated with Changes in Relative Abundance, Diversity and Richness of the Oral and Gastrointestinal Microbiome during Autologous Transplantation for Multiple Myeloma: Results of a Prospective Pilot Study Biology of Blood and Marrow Transplantation. 25. DOI: 10.1016/J.Bbmt.2018.12.835 |
0.327 |
|
| 2018 |
Aid M, Dupuy FP, Moysi E, Moir S, Haddad EK, Estes JD, Sekaly RP, Petrovas C, Ribeiro SP. Follicular CD4 T Helper Cells As a Major HIV Reservoir Compartment: A Molecular Perspective. Frontiers in Immunology. 9: 895. PMID 29967602 DOI: 10.3389/Fimmu.2018.00895 |
0.37 |
|
| 2018 |
Vaccari M, Fourati S, Gordon SN, Brown DR, Bissa M, Schifanella L, Silva de Castro I, Doster MN, Galli V, Omsland M, Fujikawa D, Gorini G, Liyanage NPM, Trinh HV, McKinnon KM, ... Sekaly RP, et al. HIV vaccine candidate activation of hypoxia and the inflammasome in CD14 monocytes is associated with a decreased risk of SIV acquisition. Nature Medicine. PMID 29785023 DOI: 10.1038/S41591-018-0025-7 |
0.328 |
|
| 2018 |
Kityo C, Makamdop KN, Rothenberger M, Chipman JG, Hoskuldsson T, Beilman GJ, Grzywacz B, Mugyenyi P, Ssali F, Akondy RS, Anderson J, Schmidt TE, Reimann T, Callisto SP, Schoephoerster J, ... Sekaly RP, et al. Lymphoid tissue fibrosis is associated with impaired vaccine responses. The Journal of Clinical Investigation. PMID 29781814 DOI: 10.1172/Jci97377 |
0.325 |
|
| 2018 |
Evans VA, Van Der Sluis RM, Solomon A, Dantanarayana A, McNeil C, Garsia R, Palmer S, Fromentin R, Chomont N, Sékaly RP, Cameron PU, Lewin SR. PD-1 contributes to the establishment and maintenance of HIV-1 latency. Aids (London, England). PMID 29746296 DOI: 10.1097/Qad.0000000000001849 |
0.401 |
|
| 2018 |
Carnathan D, Lawson B, Yu J, Patel K, Billingsley JM, Tharp GK, Delmas OM, Dawoud R, Wilkinson P, Nicolette C, Cameron MJ, Sekaly RP, Bosinger SE, Silvestri G, Vanderford TH. Reduced chronic lymphocyte activation following Interferon-α blockade in the acute phase of SIV infection in rhesus macaques. Journal of Virology. PMID 29467313 DOI: 10.1128/Jvi.01760-17 |
0.341 |
|
| 2018 |
Sharma A, Roe A, Lopes FB, Liu R, Reese J, Ribeiro SP, Sekaly R, Lima Md, Wald D. Automated Generation and Phenotypic Characterization of Clinical Grade CD19 CAR-T Cells Blood. 132: 1675-1675. DOI: 10.1182/Blood-2018-99-120098 |
0.465 |
|
| 2017 |
Gavegnano C, Brehm JH, Dupuy FP, Talla A, Ribeiro SP, Kulpa DA, Cameron C, Santos S, Hurwitz SJ, Marconi VC, Routy JP, Sabbagh L, Schinazi RF, Sékaly RP. Novel mechanisms to inhibit HIV reservoir seeding using Jak inhibitors. Plos Pathogens. 13: e1006740. PMID 29267399 DOI: 10.1371/Journal.Ppat.1006740 |
0.371 |
|
| 2017 |
Gaya M, Barral P, Burbage M, Aggarwal S, Montaner B, Warren Navia A, Aid M, Tsui C, Maldonado P, Nair U, Ghneim K, Fallon PG, Sekaly RP, Barouch DH, Shalek AK, et al. Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells. Cell. PMID 29249358 DOI: 10.1016/J.Cell.2017.11.036 |
0.401 |
|
| 2017 |
McGary CS, Deleage C, Harper J, Micci L, Ribeiro SP, Paganini S, Kuri-Cervantes L, Benne C, Ryan ES, Balderas R, Jean S, Easley K, Marconi V, Silvestri G, Estes JD, ... Sekaly RP, et al. CTLA-4(+)PD-1(-) Memory CD4(+) T Cells Critically Contribute to Viral Persistence in Antiretroviral Therapy-Suppressed, SIV-Infected Rhesus Macaques. Immunity. 47: 776-788.e5. PMID 29045906 DOI: 10.1016/J.Immuni.2017.09.018 |
0.455 |
|
| 2017 |
Wu G, Swanson M, Talla A, Graham D, Strizki J, Gorman D, Barnard RJ, Blair W, Søgaard OS, Tolstrup M, Østergaard L, Rasmussen TA, Sekaly RP, Archin NM, Margolis DM, et al. HDAC inhibition induces HIV-1 protein and enables immune-based clearance following latency reversal. Jci Insight. 2. PMID 28814661 DOI: 10.1172/Jci.Insight.92901 |
0.468 |
|
| 2017 |
Abdelsamed HA, Moustaki A, Fan Y, Dogra P, Ghoneim HE, Zebley CC, Triplett BM, Sekaly RP, Youngblood B. Human memory CD8 T cell effector potential is epigenetically preserved during in vivo homeostasis. The Journal of Experimental Medicine. PMID 28490440 DOI: 10.1084/Jem.20161760 |
0.419 |
|
| 2017 |
Peterson CW, Benne C, Polacino P, Kaur J, McAllister CE, Filali-Mouhim A, Obenza W, Pecor TA, Huang ML, Baldessari A, Murnane RD, Woolfrey AE, Jerome KR, Hu SL, Klatt NR, et al. Loss of immune homeostasis dictates SHIV rebound after stem-cell transplantation. Jci Insight. 2: e91230. PMID 28239658 DOI: 10.1172/Jci.Insight.91230 |
0.375 |
|
| 2017 |
Deeks SG, Odorizzi PM, Sekaly RP. The interferon paradox: can inhibiting an antiviral mechanism advance an HIV cure? The Journal of Clinical Investigation. 127: 103-105. PMID 27941242 DOI: 10.1172/Jci91916 |
0.385 |
|
| 2016 |
Scheid E, Major P, Bergeron A, Finn OJ, Salter RD, Eady R, Yassine-Diab B, Favre D, Peretz Y, Landry C, Hotte S, Mukherjee S, Dekaban GA, Fink C, Foster P, ... ... Sekaly RP, et al. Tn-MUC1 DC Vaccination of Rhesus Macaques and a Phase I/II Trial in Patients with Non-Metastatic Castrate Resistant Prostate Cancer. Cancer Immunology Research. PMID 27604597 DOI: 10.1158/2326-6066.Cir-15-0189 |
0.388 |
|
| 2016 |
Liu J, Ghneim K, Sok D, Bosche WJ, Li Y, Chipriano E, Berkemeier B, Oswald K, Borducchi E, Cabral C, Peter L, Brinkman A, Shetty M, Jimenez J, Mondesir J, ... ... Sekaly RP, et al. Antibody-mediated protection against SHIV challenge includes systemic clearance of distal virus. Science (New York, N.Y.). PMID 27540005 DOI: 10.1126/Science.Aag0491 |
0.316 |
|
| 2016 |
DeGottardi MQ, Okoye AA, Vaidya M, Talla A, Konfe AL, Reyes MD, Clock JA, Duell DM, Legasse AW, Sabnis A, Park BS, Axthelm MK, Estes JD, Reiman KA, Sekaly RP, et al. Effect of Anti-IL-15 Administration on T Cell and NK Cell Homeostasis in Rhesus Macaques. Journal of Immunology (Baltimore, Md. : 1950). PMID 27430715 DOI: 10.4049/Jimmunol.1600065 |
0.339 |
|
| 2016 |
Fromentin R, Bakeman W, Lawani MB, Khoury G, Hartogensis W, DaFonseca S, Killian M, Epling L, Hoh R, Sinclair E, Hecht FM, Bacchetti P, Deeks SG, Lewin SR, Sékaly RP, et al. CD4+ T Cells Expressing PD-1, TIGIT and LAG-3 Contribute to HIV Persistence during ART. Plos Pathogens. 12: e1005761. PMID 27415008 DOI: 10.1371/Journal.Ppat.1005761 |
0.396 |
|
| 2016 |
Kuri-Cervantes L, Fourati S, Canderan G, Sekaly RP. Systems biology and the quest for correlates of protection to guide the development of an HIV vaccine. Current Opinion in Immunology. 41: 91-97. PMID 27392184 DOI: 10.1016/J.Coi.2016.06.010 |
0.366 |
|
| 2016 |
Pandiyan P, Younes SA, Ribeiro SP, Talla A, McDonald D, Bhaskaran N, Levine AD, Weinberg A, Sekaly RP. Mucosal Regulatory T Cells and T Helper 17 Cells in HIV-Associated Immune Activation. Frontiers in Immunology. 7: 228. PMID 27379092 DOI: 10.3389/Fimmu.2016.00228 |
0.393 |
|
| 2016 |
Dagenais-Lussier X, Aounallah M, Mehraj V, El-Far M, Tremblay C, Sekaly RP, Routy JP, van Grevenynghe J. Kynurenine Reduces Memory CD4 T-cell Survival by Interfering with IL-2 Signaling early During HIV-1 Infection. Journal of Virology. PMID 27356894 DOI: 10.1128/Jvi.00994-16 |
0.46 |
|
| 2016 |
Younes SA, Freeman ML, Mudd JC, Shive CL, Reynaldi A, Panigrahi S, Estes JD, Deleage C, Lucero C, Anderson J, Schacker TW, Davenport MP, McCune JM, Hunt PW, Lee SA, ... ... Sekaly RP, et al. IL-15 promotes activation and expansion of CD8+ T cells in HIV-1 infection. The Journal of Clinical Investigation. PMID 27322062 DOI: 10.1172/Jci85996 |
0.409 |
|
| 2016 |
Vaccari M, Gordon SN, Fourati S, Schifanella L, Liyanage NP, Cameron M, Keele BF, Shen X, Tomaras GD, Billings E, Rao M, Chung AW, Dowell KG, Bailey-Kellogg C, Brown EP, ... ... Sekaly RP, et al. Adjuvant-dependent innate and adaptive immune signatures of risk of SIVmac251 acquisition. Nature Medicine. 22: 762-70. PMID 27239761 DOI: 10.1038/Nm.4105 |
0.343 |
|
| 2016 |
Barouch DH, Ghneim K, Bosche WJ, Li Y, Berkemeier B, Hull M, Bhattacharyya S, Cameron M, Liu J, Smith K, Borducchi E, Cabral C, Peter L, Brinkman A, Shetty M, ... ... Sekaly RP, et al. Rapid Inflammasome Activation following Mucosal SIV Infection of Rhesus Monkeys. Cell. PMID 27085913 DOI: 10.1016/J.Cell.2016.03.021 |
0.357 |
|
| 2016 |
Liu J, Haddad EK, Marceau J, Morabito KM, Rao SS, Filali-Mouhim A, Sekaly RP, Graham BS. A Numerically Subdominant CD8 T Cell Response to Matrix Protein of Respiratory Syncytial Virus Controls Infection with Limited Immunopathology. Plos Pathogens. 12: e1005486. PMID 26943673 DOI: 10.1371/Journal.Ppat.1005486 |
0.384 |
|
| 2015 |
Cleret-Buhot A, Zhang Y, Planas D, Goulet JP, Monteiro P, Gosselin A, Wacleche VS, Tremblay CL, Jenabian MA, Routy JP, El-Far M, Chomont N, Haddad EK, Sekaly RP, Ancuta P. Identification of novel HIV-1 dependency factors in primary CCR4(+)CCR6(+)Th17 cells via a genome-wide transcriptional approach. Retrovirology. 12: 102. PMID 26654242 DOI: 10.1186/S12977-015-0226-9 |
0.438 |
|
| 2015 |
Procopio FA, Fromentin R, Kulpa DA, Brehm JH, Bebin AG, Strain MC, Richman DD, O'Doherty U, Palmer S, Hecht FM, Hoh R, Barnard RJ, Miller MD, Hazuda DJ, Deeks SG, et al. A Novel Assay to Measure the Magnitude of the Inducible Viral Reservoir in HIV-infected Individuals. Ebiomedicine. 2: 872-81. PMID 26425694 DOI: 10.1016/J.Ebiom.2015.06.019 |
0.384 |
|
| 2015 |
Dagenais-Lussier X, Mouna A, Routy JP, Tremblay C, Sekaly RP, El-Far M, Grevenynghe Jv. Current topics in HIV-1 pathogenesis: The emergence of deregulated immuno-metabolism in HIV-infected subjects. Cytokine & Growth Factor Reviews. 26: 603-13. PMID 26409789 DOI: 10.1016/J.Cytogfr.2015.09.001 |
0.397 |
|
| 2015 |
El-Far M, Ancuta P, Routy JP, Zhang Y, Bakeman W, Bordi R, DaFonseca S, Said EA, Gosselin A, Tep TS, Eichbaum Q, van Grevenynghe J, Schwartz O, Freeman GJ, Haddad EK, et al. Nef promotes evasion of human immunodeficiency virus type 1-infected cells from the CTLA-4-mediated inhibition of T-cell activation. The Journal of General Virology. 96: 1463-77. PMID 25626682 DOI: 10.1099/Vir.0.000065 |
0.425 |
|
| 2015 |
Delaloye J, Filali-Mouhim A, Cameron MJ, Haddad EK, Harari A, Goulet JP, Gomez CE, Perdiguero B, Esteban M, Pantaleo G, Roger T, Sékaly RP, Calandra T. Interleukin-1- and type I interferon-dependent enhanced immunogenicity of an NYVAC-HIV-1 Env-Gag-Pol-Nef vaccine vector with dual deletions of type I and type II interferon-binding proteins. Journal of Virology. 89: 3819-32. PMID 25609807 DOI: 10.1128/Jvi.03061-14 |
0.367 |
|
| 2015 |
Roychoudhuri R, Lefebvre F, Honda M, Pan L, Ji Y, Klebanoff CA, Nichols CN, Fourati S, Hegazy AN, Goulet JP, Gattinoni L, Nabel GJ, Gilliet M, Cameron M, Restifo NP, et al. Transcriptional profiles reveal a stepwise developmental program of memory CD8(+) T cell differentiation. Vaccine. 33: 914-23. PMID 25446821 DOI: 10.1016/J.Vaccine.2014.10.007 |
0.345 |
|
| 2015 |
Nakanjako D, Ssinabulya I, Nabatanzi R, Bayigga L, Kiragga A, Joloba M, Kaleebu P, Kambugu AD, Kamya MR, Sekaly R, Elliott A, Mayanja-Kizza H. Atorvastatin reduces T-cell activation and exhaustion among HIV-infected cART-treated suboptimal immune responders in Uganda: a randomised crossover placebo-controlled trial. Tropical Medicine & International Health : Tm & Ih. 20: 380-90. PMID 25441397 DOI: 10.1111/tmi.12442 |
0.342 |
|
| 2015 |
Zeidan J, Lee G, Fromentin R, Lalezari J, Mitsuyasu R, Wang S, Giedlin MA, Nichol G, Tang W, Chomont N, Ando D, Sekaly R. C-7. Adoptive Transfer of ZFN Mediated CCR5 Modified CD4 T-cells (SB-728-T) in HIV Subjects Leads to Long Term Engraftment of HIV Resistant T Memory Stem Cells and Decrease in Size of Latent Reservoir Molecular Therapy. 23. DOI: 10.1016/S1525-0016(16)33865-5 |
0.487 |
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| 2014 |
Elliott JH, Wightman F, Solomon A, Ghneim K, Ahlers J, Cameron MJ, Smith MZ, Spelman T, McMahon J, Velayudham P, Brown G, Roney J, Watson J, Prince MH, Hoy JF, et al. Activation of HIV transcription with short-course vorinostat in HIV-infected patients on suppressive antiretroviral therapy. Plos Pathogens. 10: e1004473. PMID 25393648 DOI: 10.1371/Journal.Ppat.1004473 |
0.441 |
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| 2014 |
Streeck H, Lu R, Beckwith N, Milazzo M, Liu M, Routy JP, Little S, Jessen H, Kelleher AD, Hecht F, Sekaly RP, Alter G, Heckerman D, Carrington M, Rosenberg ES, et al. Emergence of individual HIV-specific CD8 T cell responses during primary HIV-1 infection can determine long-term disease outcome. Journal of Virology. 88: 12793-801. PMID 25165102 DOI: 10.1128/Jvi.02016-14 |
0.491 |
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| 2014 |
Muyanja E, Ssemaganda A, Ngauv P, Cubas R, Perrin H, Srinivasan D, Canderan G, Lawson B, Kopycinski J, Graham AS, Rowe DK, Smith MJ, Isern S, Michael S, Silvestri G, ... ... Sekaly RP, et al. Immune activation alters cellular and humoral responses to yellow fever 17D vaccine. The Journal of Clinical Investigation. 124: 3147-58. PMID 24911151 DOI: 10.1172/Jci75429 |
0.324 |
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| 2014 |
Cockerham LR, Jain V, Sinclair E, Glidden DV, Hartogenesis W, Hatano H, Hunt PW, Martin JN, Pilcher CD, Sekaly R, McCune JM, Hecht FM, Deeks SG. Programmed death-1 expression on CD4⁺ and CD8⁺ T cells in treated and untreated HIV disease. Aids (London, England). 28: 1749-58. PMID 24871455 DOI: 10.1097/Qad.0000000000000314 |
0.315 |
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| 2014 |
Thiébaut R, Drylewicz J, Prague M, Lacabaratz C, Beq S, Jarne A, Croughs T, Sekaly RP, Lederman MM, Sereti I, Commenges D, Lévy Y. Quantifying and predicting the effect of exogenous interleukin-7 on CD4+ T cells in HIV-1 infection. Plos Computational Biology. 10: e1003630. PMID 24853554 DOI: 10.1371/Journal.Pcbi.1003630 |
0.38 |
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| 2014 |
Girard T, Gaucher D, El-Far M, Breton G, Sékaly RP. CD80 and CD86 IgC domains are important for quaternary structure, receptor binding and co-signaling function. Immunology Letters. 161: 65-75. PMID 24845157 DOI: 10.1016/J.Imlet.2014.05.002 |
0.35 |
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| 2014 |
Fortin JS, Genève L, Gauthier C, Shoukry NH, Azar GA, Younes S, Yassine-Diab B, Sékaly RP, Fremont DH, Thibodeau J. MMTV superantigens coerce an unconventional topology between the TCR and MHC class II. Journal of Immunology (Baltimore, Md. : 1950). 192: 1896-906. PMID 24453254 DOI: 10.4049/Jimmunol.1203130 |
0.306 |
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| 2014 |
Vaccari M, Gordon SN, Fourati S, Schifanella L, Cameron M, Keele BF, Shen X, Tomaras G, Billings E, Rao M, Liyanage NP, Vargas-Inchaustegui DA, Whitney S, Doster MN, Binello N, ... ... Sekaly R, et al. Adjuvant Dependent Mucosal V2 Responses and RAS Activation in Vaccine Induced Protection from SIVmac251 Acquisition Aids Research and Human Retroviruses. 30: A64-A65. DOI: 10.1089/Aid.2014.5117.Abstract |
0.384 |
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| 2013 |
Evans VA, Kumar N, Filali A, Procopio FA, Yegorov O, Goulet JP, Saleh S, Haddad EK, da Fonseca Pereira C, Ellenberg PC, Sekaly RP, Cameron PU, Lewin SR. Myeloid dendritic cells induce HIV-1 latency in non-proliferating CD4+ T cells. Plos Pathogens. 9: e1003799. PMID 24339779 DOI: 10.1371/journal.ppat.1003799 |
0.419 |
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| 2013 |
Phetsouphanh C, Xu Y, Amin J, Seddiki N, Procopio F, Sekaly RP, Zaunders JJ, Kelleher AD. Characterization of transcription factor phenotypes within antigen-specific CD4+ T cells using qualitative multiplex single-cell RT-PCR. Plos One. 8: e74946. PMID 24124462 DOI: 10.1371/Journal.Pone.0074946 |
0.339 |
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| 2013 |
Breton G, Chomont N, Takata H, Fromentin R, Ahlers J, Filali-Mouhim A, Riou C, Boulassel MR, Routy JP, Yassine-Diab B, Sékaly RP. Programmed death-1 is a marker for abnormal distribution of naive/memory T cell subsets in HIV-1 infection. Journal of Immunology (Baltimore, Md. : 1950). 191: 2194-204. PMID 23918986 DOI: 10.4049/Jimmunol.1200646 |
0.372 |
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| 2013 |
Lederman MM, Funderburg NT, Sekaly RP, Klatt NR, Hunt PW. Residual immune dysregulation syndrome in treated HIV infection. Advances in Immunology. 119: 51-83. PMID 23886064 DOI: 10.1016/B978-0-12-407707-2.00002-3 |
0.336 |
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| 2013 |
Vandergeeten C, Fromentin R, DaFonseca S, Lawani MB, Sereti I, Lederman MM, Ramgopal M, Routy JP, Sékaly RP, Chomont N. Interleukin-7 promotes HIV persistence during antiretroviral therapy. Blood. 121: 4321-9. PMID 23589672 DOI: 10.1182/Blood-2012-11-465625 |
0.377 |
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| 2013 |
Katlama C, Deeks SG, Autran B, Martinez-Picado J, van Lunzen J, Rouzioux C, Miller M, Vella S, Schmitz JE, Ahlers J, Richman DD, Sekaly RP. Barriers to a cure for HIV: new ways to target and eradicate HIV-1 reservoirs. Lancet. 381: 2109-17. PMID 23541541 DOI: 10.1016/S0140-6736(13)60104-X |
0.308 |
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| 2013 |
Vaccari M, Halwani R, Patterson LJ, Boasso A, Beal J, Tryniszewska E, Hryniewicz A, Venzon D, Haddad EK, El-Far M, Rosati M, Pavlakis GN, Felber BK, Al-Muhsen S, Robert-Guroff M, ... Sekaly RP, et al. Antibodies to gp120 and PD-1 expression on virus-specific CD8+ T cells in protection from simian AIDS. Journal of Virology. 87: 3526-37. PMID 23325679 DOI: 10.1128/JVI.02686-12 |
0.337 |
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| 2013 |
Tzelepis F, Joseph J, Haddad EK, Maclean S, Dudani R, Agenes F, Peng SL, Sekaly RP, Sad S. Intrinsic role of FoxO3a in the development of CD8+ T cell memory. Journal of Immunology (Baltimore, Md. : 1950). 190: 1066-75. PMID 23277488 DOI: 10.4049/Jimmunol.1200639 |
0.35 |
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| 2013 |
Costiniuk CT, Kovacs C, Routy JP, Singer J, Gurunathan S, Sekaly RP, Angel JB. Short communication: human immunodeficiency virus rebound in blood and seminal plasma following discontinuation of antiretroviral therapy. Aids Research and Human Retroviruses. 29: 266-9. PMID 22908887 DOI: 10.1089/Aid.2011.0343 |
0.353 |
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| 2013 |
Sekaly R, Zeidan J, Lalezari J, Mitsuyasu R, Lee G, Giedlin M, Nichol G, Tang W, Ando D, Deeks S. CD4 reconstitution and reduction of reservoir in HIV-positive patients following a single infusion of CCR5 modified autologous CD4 T cells (SB-728-T) The Lancet. 382: S21. DOI: 10.1016/S0140-6736(13)62269-2 |
0.358 |
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| 2012 |
Doroudchi M, Yegorov O, Baumgartner T, Kernaleguen AE, Breton G, Ndongala ML, Boulassel MR, Routy JP, Bernard NF, Sékaly RP, Yassine-Diab B. Autologous HIV-1 clade-B Nef peptides elicit increased frequency, breadth and function of CD8+ T-cells compared to consensus peptides. Plos One. 7: e49562. PMID 23185362 DOI: 10.1371/Journal.Pone.0049562 |
0.34 |
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| 2012 |
Fukazawa Y, Park H, Cameron MJ, Lefebvre F, Lum R, Coombes N, Mahyari E, Hagen SI, Bae JY, Reyes MD, Swanson T, Legasse AW, Sylwester A, Hansen SG, Smith AT, et al. Lymph node T cell responses predict the efficacy of live attenuated SIV vaccines. Nature Medicine. 18: 1673-81. PMID 22961108 DOI: 10.1038/Nm.2934 |
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| 2012 |
Trautmann L, Mbitikon-Kobo FM, Goulet JP, Peretz Y, Shi Y, Van Grevenynghe J, Procopio FA, Boulassel MR, Routy JP, Chomont N, Haddad EK, Sekaly RP. Profound metabolic, functional, and cytolytic differences characterize HIV-specific CD8 T cells in primary and chronic HIV infection. Blood. 120: 3466-77. PMID 22955926 DOI: 10.1182/blood-2012-04-422550 |
0.35 |
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| 2012 |
van Grevenynghe J, Cubas RA, DaFonseca S, Metcalf T, Tremblay CL, Trautmann L, Sekaly RP, Schatzle J, Haddad EK. Foxo3a: an integrator of immune dysfunction during HIV infection. Cytokine & Growth Factor Reviews. 23: 215-21. PMID 22748238 DOI: 10.1016/J.Cytogfr.2012.05.008 |
0.451 |
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| 2012 |
Girard T, El-Far M, Gaucher D, Acuto O, Beaulé G, Michel F, Mourad W, Sékaly RP. A conserved polylysine motif in CD86 cytoplasmic tail is necessary for cytoskeletal association and effective co-stimulation. Biochemical and Biophysical Research Communications. 423: 301-7. PMID 22659416 DOI: 10.1016/J.Bbrc.2012.05.116 |
0.395 |
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| 2012 |
Johnson MJ, Petrovas C, Yamamoto T, Lindsay RW, Loré K, Gall JG, Gostick E, Lefebvre F, Cameron MJ, Price DA, Haddad E, Sekaly RP, Seder RA, Koup RA. Type I IFN induced by adenovirus serotypes 28 and 35 has multiple effects on T cell immunogenicity. Journal of Immunology (Baltimore, Md. : 1950). 188: 6109-18. PMID 22586038 DOI: 10.4049/Jimmunol.1103717 |
0.311 |
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| 2012 |
Janbazian L, Price DA, Canderan G, Filali-Mouhim A, Asher TE, Ambrozak DR, Scheinberg P, Boulassel MR, Routy JP, Koup RA, Douek DC, Sekaly RP, Trautmann L. Clonotype and repertoire changes drive the functional improvement of HIV-specific CD8 T cell populations under conditions of limited antigenic stimulation. Journal of Immunology (Baltimore, Md. : 1950). 188: 1156-67. PMID 22210916 DOI: 10.4049/Jimmunol.1102610 |
0.391 |
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| 2012 |
Wilkinson P, Filali-Mouhim A, Li S, Ahlers J, Schatzle J, Pulendran B, Sekaly RP, Cameron MJ. An open-ended plea for the development of a global database of HIV vaccine responses Current Opinion in Hiv and Aids. 7: 10-16. PMID 22156846 DOI: 10.1097/Coh.0B013E32834E390A |
0.348 |
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| 2012 |
Peretz Y, Cameron C, Sékaly RP. Dissecting the HIV-specific immune response: a systems biology approach. Current Opinion in Hiv and Aids. 7: 17-23. PMID 22134339 DOI: 10.1097/Coh.0B013E32834Ddb0E |
0.368 |
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| 2012 |
Boulassel MR, Chomont N, Pai NP, Gilmore N, Sékaly RP, Routy JP. CD4 T cell nadir independently predicts the magnitude of the HIV reservoir after prolonged suppressive antiretroviral therapy. Journal of Clinical Virology : the Official Publication of the Pan American Society For Clinical Virology. 53: 29-32. PMID 22019250 DOI: 10.1016/J.Jcv.2011.09.018 |
0.349 |
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| 2012 |
Mbitikon-Kobo FM, Bonneville M, Sekaly RP, Trautmann L. Ex vivo measurement of the cytotoxic capacity of human primary antigen-specific CD8 T cells. Journal of Immunological Methods. 375: 252-7. PMID 21996428 DOI: 10.1016/j.jim.2011.09.008 |
0.359 |
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| 2012 |
Gómez C, Perdiguero B, Jimenez V, Filali-Mouhim A, Ghneim K, Haddad E, Quakkerlaar E, Delaloye J, Harari A, Roger T, Duhem T, Sekaly R, Melief C, Calandra T, Sallusto F, et al. Systems analysis of MVA-C induced immune response reveals its significance as a vaccine candidate against HIV/AIDS of clade C Retrovirology. 9: 303. DOI: 10.1186/1742-4690-9-S2-P303 |
0.344 |
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| 2012 |
Liyanage N, Pegu P, Gordon S, Cameron M, Foulds K, Doster M, Vaccari M, Koup R, Roederer M, Sékaly R, Franchini G. RV144-like trial in macaques using ALVAC-SIV & gp120 induces innate immunity and increases the frequency of NK22 & NKG2A+ cells in mucosal tissues Retrovirology. 9. DOI: 10.1186/1742-4690-9-S2-O14 |
0.334 |
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| 2012 |
Spaans JN, Routy JP, Tremblay C, Singer J, Bernard N, Gurunathan S, Sékaly RP, Angel JB. Optimizing the efficiency of therapeutic HIV vaccine trials: A case for CTN 173 Trials in Vaccinology. 1: 21-26. DOI: 10.1016/J.Trivac.2012.01.003 |
0.354 |
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| 2011 |
Angel JB, Routy JP, Tremblay C, Ayers D, Woods R, Singer J, Bernard N, Kovacs C, Smaill F, Gurunathan S, Sekaly RP. A randomized controlled trial of HIV therapeutic vaccination using ALVAC with or without Remune. Aids (London, England). 25: 731-9. PMID 21330911 DOI: 10.1097/Qad.0B013E328344Cea5 |
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| 2011 |
Chomont N, DaFonseca S, Vandergeeten C, Ancuta P, Sékaly RP. Maintenance of CD4+ T-cell memory and HIV persistence: keeping memory, keeping HIV. Current Opinion in Hiv and Aids. 6: 30-6. PMID 21242891 DOI: 10.1097/Coh.0B013E3283413775 |
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| 2011 |
DaFonseca S, El-Far M, Boulassel M, Routy J, Sékaly R, Chomont N. A role for negative regulators of T cell activation in the establishment and maintenance of the HIV reservoir F1000research. 2. DOI: 10.7490/F1000Research.1927.1 |
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| 2010 |
Perrin H, Canderan G, Sékaly RP, Trautmann L. New approaches to design HIV-1 T-cell vaccines. Current Opinion in Hiv and Aids. 5: 368-76. PMID 20978376 DOI: 10.1097/Coh.0B013E32833D2Cc0 |
0.436 |
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| 2010 |
Cameron PU, Saleh S, Sallmann G, Solomon A, Wightman F, Evans VA, Boucher G, Haddad EK, Sekaly RP, Harman AN, Anderson JL, Jones KL, Mak J, Cunningham AL, Jaworowski A, et al. Establishment of HIV-1 latency in resting CD4+ T cells depends on chemokine-induced changes in the actin cytoskeleton. Proceedings of the National Academy of Sciences of the United States of America. 107: 16934-9. PMID 20837531 DOI: 10.1073/Pnas.1002894107 |
0.499 |
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| 2010 |
Ancuta P, Monteiro P, Sekaly RP. Th17 lineage commitment and HIV-1 pathogenesis. Current Opinion in Hiv and Aids. 5: 158-65. PMID 20543594 DOI: 10.1097/Coh.0B013E3283364733 |
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| 2010 |
Ndongala ML, Kamya P, Boulet S, Peretz Y, Rouleau D, Tremblay C, Leblanc R, Côté P, Baril JG, Thomas R, Vézina S, Boulassel MR, Routy JP, Sékaly RP, Bernard NF. Changes in function of HIV-specific T-cell responses with increasing time from infection. Viral Immunology. 23: 159-68. PMID 20373996 DOI: 10.1089/Vim.2009.0084 |
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| 2010 |
Rodrigue-Gervais IG, Rigsby H, Jouan L, Sauvé D, Sékaly RP, Willems B, Lamarre D. Dendritic cell inhibition is connected to exhaustion of CD8+ T cell polyfunctionality during chronic hepatitis C virus infection. Journal of Immunology (Baltimore, Md. : 1950). 184: 3134-44. PMID 20173023 DOI: 10.4049/Jimmunol.0902522 |
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| 2010 |
Gosselin A, Monteiro P, Chomont N, Diaz-Griffero F, Said EA, Fonseca S, Wacleche V, El-Far M, Boulassel MR, Routy JP, Sekaly RP, Ancuta P. Peripheral blood CCR4+CCR6+ and CXCR3+CCR6+CD4+ T cells are highly permissive to HIV-1 infection. Journal of Immunology (Baltimore, Md. : 1950). 184: 1604-16. PMID 20042588 DOI: 10.4049/Jimmunol.0903058 |
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| 2010 |
Routy JP, Boulassel MR, Yassine-Diab B, Nicolette C, Healey D, Jain R, Landry C, Yegorov O, Tcherepanova I, Monesmith T, Finke L, Sékaly RP. Immunologic activity and safety of autologous HIV RNA-electroporated dendritic cells in HIV-1 infected patients receiving antiretroviral therapy. Clinical Immunology (Orlando, Fla.). 134: 140-7. PMID 19889582 DOI: 10.1016/J.Clim.2009.09.009 |
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| 2010 |
Saïdi H, Carbonneil C, Magri G, Eslahpazir J, Sekaly RP, Bélec L. Differential modulation of CCR5-tropic human immunodeficiency virus-1 transfer from macrophages towards T cells under interleukin-4/interleukin-13 microenvironment. Human Immunology. 71: 1-13. PMID 19706316 DOI: 10.1016/J.Humimm.2009.08.011 |
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| 2009 |
Horton RE, Kaefer N, Songok E, Guijon FB, Kettaf N, Boucher G, Sekaly RP, Ball TB, Plummer FA. A comparative analysis of gene expression patterns and cell phenotypes between cervical and peripheral blood mononuclear cells. Plos One. 4: e8293. PMID 20011545 DOI: 10.1371/Journal.Pone.0008293 |
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| 2009 |
Chomont N, El-Far M, Ancuta P, Trautmann L, Procopio FA, Yassine-Diab B, Boucher G, Boulassel MR, Ghattas G, Brenchley JM, Schacker TW, Hill BJ, Douek DC, Routy JP, Haddad EK, et al. HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation. Nature Medicine. 15: 893-900. PMID 19543283 DOI: 10.1038/Nm.1972 |
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| 2009 |
Streeck H, Jolin JS, Qi Y, Yassine-Diab B, Johnson RC, Kwon DS, Addo MM, Brumme C, Routy JP, Little S, Jessen HK, Kelleher AD, Hecht FM, Sekaly RP, Rosenberg ES, et al. Human immunodeficiency virus type 1-specific CD8+ T-cell responses during primary infection are major determinants of the viral set point and loss of CD4+ T cells. Journal of Virology. 83: 7641-8. PMID 19458000 DOI: 10.1128/Jvi.00182-09 |
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| 2009 |
Schneidewind A, Brumme ZL, Brumme CJ, Power KA, Reyor LL, O'Sullivan K, Gladden A, Hempel U, Kuntzen T, Wang YE, Oniangue-Ndza C, Jessen H, Markowitz M, Rosenberg ES, Sékaly RP, et al. Transmission and long-term stability of compensated CD8 escape mutations. Journal of Virology. 83: 3993-7. PMID 19091871 DOI: 10.1128/Jvi.01108-08 |
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| 2009 |
Gosselin A, Monteiro P, Chomont N, Diaz-Griffero F, Wacleche VS, Said EA, Fonseca S, El-Far M, Boulassel M, Routy J, Sekaly R, Ancuta P. P16-54 LB. Blood CCR6+ Th17 and Th1Th17 but not CCR6neg Th1 cells are targets for HIV replication and their frequency is diminished in HIV-infected subjects Retrovirology. 6. DOI: 10.1186/1742-4690-6-S3-P407 |
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| 2008 |
Dulude G, Cheynier R, Gauchat D, Abdallah A, Kettaf N, Sékaly RP, Gratton S. The magnitude of thymic output is genetically determined through controlled intrathymic precursor T cell proliferation. Journal of Immunology (Baltimore, Md. : 1950). 181: 7818-24. PMID 19017971 DOI: 10.4049/Jimmunol.181.11.7818 |
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| 2008 |
Démoulins T, Abdallah A, Kettaf N, Baron ML, Gerarduzzi C, Gauchat D, Gratton S, Sékaly RP. Reversible blockade of thymic output: an inherent part of TLR ligand-mediated immune response. Journal of Immunology (Baltimore, Md. : 1950). 181: 6757-69. PMID 18981093 DOI: 10.4049/Jimmunol.181.10.6757 |
0.386 |
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| 2008 |
Badr G, Bédard N, Abdel-Hakeem MS, Trautmann L, Willems B, Villeneuve JP, Haddad EK, Sékaly RP, Bruneau J, Shoukry NH. Early interferon therapy for hepatitis C virus infection rescues polyfunctional, long-lived CD8+ memory T cells. Journal of Virology. 82: 10017-31. PMID 18667516 DOI: 10.1128/Jvi.01083-08 |
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| 2008 |
Salha MD, Cheynier R, Halwani R, McGrath H, Langaee TY, Yassine Diab B, Fournier J, Parenteau M, Edgar J, Ko D, Sherring A, Bogdanovic D, Sekaly RP, Rud EW. Persistence of restricted CD4 T cell expansions in SIV-infected macaques resistant to SHIV89.6P superinfection. Virology. 377: 239-47. PMID 18570962 DOI: 10.1016/j.virol.2008.04.031 |
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| 2008 |
Halwani R, Boyer JD, Yassine-Diab B, Haddad EK, Robinson TM, Kumar S, Parkinson R, Wu L, Sidhu MK, Phillipson-Weiner R, Pavlakis GN, Felber BK, Lewis MG, Shen A, Siliciano RF, ... ... Sekaly RP, et al. Therapeutic vaccination with simian immunodeficiency virus (SIV)-DNA + IL-12 or IL-15 induces distinct CD8 memory subsets in SIV-infected macaques. Journal of Immunology (Baltimore, Md. : 1950). 180: 7969-79. PMID 18523260 DOI: 10.4049/Jimmunol.180.12.7969 |
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| 2008 |
Baron ML, Gauchat D, La Motte-Mohs R, Kettaf N, Abdallah A, Michiels T, Zúñiga-Pflücker JC, Sékaly RP. TLR Ligand-Induced Type I IFNs Affect Thymopoiesis. Journal of Immunology (Baltimore, Md. : 1950). 180: 7134-46. PMID 18490712 DOI: 10.4049/Jimmunol.180.11.7134 |
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| 2008 |
El-Far M, Halwani R, Said E, Trautmann L, Doroudchi M, Janbazian L, Fonseca S, van Grevenynghe J, Yassine-Diab B, Sékaly RP, Haddad EK. T-cell exhaustion in HIV infection. Current Hiv/Aids Reports. 5: 13-9. PMID 18417030 DOI: 10.1007/S11904-008-0003-7 |
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van Grevenynghe J, Procopio FA, He Z, Chomont N, Riou C, Zhang Y, Gimmig S, Boucher G, Wilkinson P, Shi Y, Yassine-Diab B, Said EA, Trautmann L, El Far M, Balderas RS, ... ... Sekaly RP, et al. Transcription factor FOXO3a controls the persistence of memory CD4(+) T cells during HIV infection. Nature Medicine. 14: 266-74. PMID 18311149 DOI: 10.1038/Nm1728 |
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| 2008 |
Blais ME, Brochu S, Giroux M, Bélanger MP, Dulude G, Sékaly RP, Perreault C. Why T cells of thymic versus extrathymic origin are functionally different. Journal of Immunology (Baltimore, Md. : 1950). 180: 2299-312. PMID 18250439 DOI: 10.4049/Jimmunol.180.4.2299 |
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| 2008 |
Requena M, Bouhlal H, Nasreddine N, Saidi H, Gody JC, Aubry S, Grésenguet G, Kazatchkine MD, Sekaly RP, Bélec L, Hocini H. Inhibition of HIV-1 transmission in trans from dendritic cells to CD4+ T lymphocytes by natural antibodies to the CRD domain of DC-SIGN purified from breast milk and intravenous immunoglobulins. Immunology. 123: 508-18. PMID 17999675 DOI: 10.1111/J.1365-2567.2007.02717.X |
0.4 |
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| 2008 |
Halwani R, Doroudchi M, El-Far M, Tanel A, Shi Y, Yassine-Diab B, Sekaly R. Role of Memory T Cells in Influenza Viral Infection Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry. 7: 87-96. DOI: 10.2174/187152308784533186 |
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| 2008 |
Boulassel M, Yassine-Diab B, Healey D, Nicolette C, Sékaly R, Routy JP. Impact of Autologous Dendritic Cell Immunotherapy (Arcelis™) on B Cell Subsets in HIV-1-Infected Subjects Receiving Antiretroviral Therapy Blood. 112: 80-80. DOI: 10.1182/BLOOD.V112.11.80.80 |
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| 2008 |
Peretz Y, Shi Y, He Z, Trautmann L, Diab BY, Haddad E, Sékaly R. 167 Elite controllers are enriched with HIV-specific cells expressing CD160 but lacking PD1 Cytokine. 43: 275-275. DOI: 10.1016/J.Cyto.2008.07.210 |
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| 2008 |
Shi Y, Trautmann L, Peretz Y, Zeidan J, Yassine-Diab B, He Z, Boulassel M, Routy J, Haddad EK, Sékaly R. 23 Impaired signaling in memory T-cells during HIV infection Cytokine. 43: 241-242. DOI: 10.1016/J.Cyto.2008.07.063 |
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| 2007 |
Chomont N, Trautmann L, Routy JP, Sékaly RP. Drug resistance mutations and the cellular immune response: a valuable synergy for the development of novel immune therapies. Current Opinion in Hiv and Aids. 2: 116-22. PMID 19372876 DOI: 10.1097/Coh.0B013E3280287A4D |
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| 2007 |
Wang C, Wen T, Routy JP, Bernard NF, Sekaly RP, Watts TH. 4-1BBL induces TNF receptor-associated factor 1-dependent Bim modulation in human T cells and is a critical component in the costimulation-dependent rescue of functionally impaired HIV-specific CD8 T cells. Journal of Immunology (Baltimore, Md. : 1950). 179: 8252-63. PMID 18056369 DOI: 10.4049/Jimmunol.179.12.8252 |
0.404 |
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| 2007 |
Sharif-Askari E, Gaucher D, Halwani R, Ma J, Jao K, Abdallah A, Haddad EK, Sékaly RP. p56Lck tyrosine kinase enhances the assembly of death-inducing signaling complex during Fas-mediated apoptosis. The Journal of Biological Chemistry. 282: 36048-56. PMID 17932036 DOI: 10.1074/Jbc.M706007200 |
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|
| 2007 |
Dion ML, Sékaly RP, Cheynier R. Estimating thymic function through quantification of T-cell receptor excision circles. Methods in Molecular Biology (Clifton, N.J.). 380: 197-213. PMID 17876095 DOI: 10.1007/978-1-59745-395-0_12 |
0.44 |
|
| 2007 |
Peretz Y, Ndongala ML, Boulet S, Boulassel MR, Rouleau D, Côté P, Longpré D, Routy JP, Falutz J, Tremblay C, Tsoukas CM, Sékaly RP, Bernard NF. Functional T cell subsets contribute differentially to HIV peptide-specific responses within infected individuals: correlation of these functional T cell subsets with markers of disease progression. Clinical Immunology (Orlando, Fla.). 124: 57-68. PMID 17521962 DOI: 10.1016/J.Clim.2007.04.004 |
0.31 |
|
| 2007 |
Streeck H, Lichterfeld M, Alter G, Meier A, Teigen N, Yassine-Diab B, Sidhu HK, Little S, Kelleher A, Routy JP, Rosenberg ES, Sekaly RP, Walker BD, Altfeld M. Recognition of a defined region within p24 GAG by CD8+ T cells during primary human immunodeficiency virus type 1 infection in individuals expressing protective HLA class I alleles Journal of Virology. 81: 7725-7731. PMID 17494064 DOI: 10.1128/Jvi.00708-07 |
0.436 |
|
| 2007 |
Rodrigue-Gervais IG, Jouan L, Beaulé G, Sauvé D, Bruneau J, Willems B, Sékaly RP, Lamarre D. Poly(I:C) and lipopolysaccharide innate sensing functions of circulating human myeloid dendritic cells are affected in vivo in hepatitis C virus-infected patients. Journal of Virology. 81: 5537-46. PMID 17376921 DOI: 10.1128/Jvi.01741-06 |
0.317 |
|
| 2007 |
Maisnier-Patin K, Crabé S, Breton G, Dupuy FP, Yassine-Diab B, Sékaly RP. [mRNA-transfected dendritic cells: a promising strategy in immunotherapy]. MéDecine Sciences : M/S. 23: 279-84. PMID 17349289 DOI: 10.1051/Medsci/2007233279 |
0.425 |
|
| 2007 |
Boulet S, Ndongala ML, Peretz Y, Boisvert MP, Boulassel MR, Tremblay C, Routy JP, Sekaly RP, Bernard NF. A dual color ELISPOT method for the simultaneous detection of IL-2 and IFN-gamma HIV-specific immune responses. Journal of Immunological Methods. 320: 18-29. PMID 17222422 DOI: 10.1016/J.Jim.2006.11.010 |
0.336 |
|
| 2007 |
Younes SA, Trautmann L, Yassine-Diab B, Kalfayan LH, Kernaleguen AE, Cameron TO, Boulassel R, Stern LJ, Routy JP, Grossman Z, Dumont AR, Sekaly RP. The duration of exposure to HIV modulates the breadth and the magnitude of HIV-specific memory CD4+ T cells. Journal of Immunology (Baltimore, Md. : 1950). 178: 788-97. PMID 17202340 DOI: 10.4049/Jimmunol.178.2.788 |
0.39 |
|
| 2007 |
Riou C, Yassine-Diab B, Van grevenynghe J, Somogyi R, Greller LD, Gagnon D, Gimmig S, Wilkinson P, Shi Y, Cameron MJ, Campos-Gonzalez R, Balderas RS, Kelvin D, Sekaly RP, Haddad EK. Convergence of TCR and cytokine signaling leads to FOXO3a phosphorylation and drives the survival of CD4+ central memory T cells. The Journal of Experimental Medicine. 204: 79-91. PMID 17190839 DOI: 10.1084/Jem.20061681 |
0.413 |
|
| 2007 |
Dion ML, Bordi R, Zeidan J, Asaad R, Boulassel MR, Routy JP, Lederman MM, Sekaly RP, Cheynier R. Slow disease progression and robust therapy-mediated CD4+ T-cell recovery are associated with efficient thymopoiesis during HIV-1 infection. Blood. 109: 2912-20. PMID 17164338 DOI: 10.1182/Blood-2006-09-047308 |
0.38 |
|
| 2007 |
Trautmann L, Said EA, Halwani R, Janbazian L, Chomont N, El-Far M, Breton G, Haddad EK, Sekaly RP. Programmed death 1: A critical regulator of T-cell function and a strong target for immunotherapies for chronic viral infections Current Opinion in Hiv and Aids. 2: 219-227. DOI: 10.1097/COH.0b013e3280ebb5c9 |
0.33 |
|
| 2006 |
Trautmann L, Janbazian L, Chomont N, Said EA, Gimmig S, Bessette B, Boulassel MR, Delwart E, Sepulveda H, Balderas RS, Routy JP, Haddad EK, Sekaly RP. Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction Nature Medicine. 12: 1198-1202. PMID 16917489 DOI: 10.1038/Nm1482 |
0.35 |
|
| 2006 |
Moldovan MC, Sabbagh L, Breton G, Sékaly RP, Krummel MF. Triggering of T cell activation via CD4 dimers. Journal of Immunology (Baltimore, Md. : 1950). 176: 5438-45. PMID 16622011 DOI: 10.4049/Jimmunol.176.9.5438 |
0.387 |
|
| 2006 |
Riou C, Dumont AR, Yassine-Diab B, Haddad EK, Sekaly RP. IL-4 influences the differentiation and the susceptibility to activation-induced cell death of human naive CD8+ T cells. International Immunology. 18: 827-35. PMID 16611649 DOI: 10.1093/Intimm/Dxl019 |
0.436 |
|
| 2006 |
Sabbagh L, Bourbonnière M, Denis F, Sékaly RP. Cloning and functional characterization of the murine caspase-3 gene promoter. Dna and Cell Biology. 25: 104-15. PMID 16460234 DOI: 10.1089/Dna.2006.25.104 |
0.319 |
|
| 2006 |
Trautmann L, Janbazian L, Chomont N, Said EA, Gimmig S, Bessette B, Boulassel M, Delwart E, Sepulveda H, Balderas RS, Routy J, Haddad EK, Sekaly R. Corrigendum: Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction Nature Medicine. 12: 1329-1329. DOI: 10.1038/Nm1106-1329B |
0.35 |
|
| 2005 |
Bukczynski J, Wen T, Wang C, Christie N, Routy JP, Boulassel MR, Kovacs CM, Macdonald KS, Ostrowski M, Sekaly RP, Bernard NF, Watts TH. Enhancement of HIV-specific CD8 T cell responses by dual costimulation with CD80 and CD137L. Journal of Immunology (Baltimore, Md. : 1950). 175: 6378-89. PMID 16272290 DOI: 10.4049/Jimmunol.175.10.6378 |
0.435 |
|
| 2005 |
Serghides L, Bukczynski J, Wen T, Wang C, Routy JP, Boulassel MR, Sekaly RP, Ostrowski M, Bernard NF, Watts TH. Evaluation of OX40 ligand as a costimulator of human antiviral memory CD8 T cell responses: comparison with B7.1 and 4-1BBL. Journal of Immunology (Baltimore, Md. : 1950). 175: 6368-77. PMID 16272289 DOI: 10.4049/Jimmunol.175.10.6368 |
0.364 |
|
| 2005 |
Sabbagh L, Bourbonnière M, Sékaly RP, Cohen LY. Selective up-regulation of caspase-3 gene expression following TCR engagement. Molecular Immunology. 42: 1345-54. PMID 15950730 DOI: 10.1016/J.Molimm.2004.12.011 |
0.318 |
|
| 2005 |
Azar GA, Sékaly RP, Thibodeau J. A defective viral superantigen-presenting phenotype in HLA-DR transfectants is corrected by CIITA. Journal of Immunology (Baltimore, Md. : 1950). 174: 7548-57. PMID 15944254 DOI: 10.4049/Jimmunol.174.12.7548 |
0.366 |
|
| 2005 |
Rose JJ, Janvier K, Chandrasekhar S, Sekaly RP, Bonifacino JS, Venkatesan S. CD4 down-regulation by HIV-1 and simian immunodeficiency virus (SIV) Nef proteins involves both internalization and intracellular retention mechanisms. The Journal of Biological Chemistry. 280: 7413-26. PMID 15611114 DOI: 10.1074/Jbc.M409420200 |
0.331 |
|
| 2005 |
Routy JP, Boulassel M, Mercier F, Grignon C, Young M, Legault M, Tremblay C, Cheynier R, Sekaly R. Expression of Interleukin-7 Receptor and Activation Markers on Central Memory CD8 Cells in HIV-Infected Individuals Treated with Antiretrovirals. Blood. 106: 1438-1438. DOI: 10.1182/Blood.V106.11.1438.1438 |
0.451 |
|
| 2004 |
Sabbagh L, Kaech SM, Bourbonnière M, Woo M, Cohen LY, Haddad EK, Labrecque N, Ahmed R, Sékaly RP. The selective increase in caspase-3 expression in effector but not memory T cells allows susceptibility to apoptosis. Journal of Immunology (Baltimore, Md. : 1950). 173: 5425-33. PMID 15494489 DOI: 10.4049/Jimmunol.173.9.5425 |
0.406 |
|
| 2004 |
Belshe R, Franchini G, Girard MP, Gotch F, Kaleebu P, Marthas ML, McChesney MB, McCullough R, Mhalu F, Salmon-Ceron D, Sekaly RP, van Rompay K, Verrier B, Wahren B, Weissenbacher M. Support for the RV144 HIV vaccine trial. Science (New York, N.Y.). 305: 177-80; author reply. PMID 15247455 DOI: 10.1126/Science.305.5681.177B |
0.31 |
|
| 2004 |
Boulassel M, Younes S, Yacine-Diab B, Sekaly R, Routy JP. Persistence of High Viral Load Abrogates Long-Term HIV-Specific Memory CD4 T-Cells Producing Interleukin-2. Blood. 104: 3104-3104. DOI: 10.1182/BLOOD.V104.11.3104.3104 |
0.384 |
|
| 2003 |
Younes SA, Yassine-Diab B, Dumont AR, Boulassel MR, Grossman Z, Routy JP, Sekaly RP. HIV-1 viremia prevents the establishment of interleukin 2-producing HIV-specific memory CD4+ T cells endowed with proliferative capacity. The Journal of Experimental Medicine. 198: 1909-22. PMID 14676302 DOI: 10.1084/Jem.20031598 |
0.501 |
|
| 2003 |
D'Souza S, McGrath H, Sékaly RP. Early activation events differentiate the reactivity of two T-cell families to Staphylococcus enterotoxin A. Cellular Immunology. 223: 113-9. PMID 14527509 DOI: 10.1016/S0008-8749(03)00156-4 |
0.339 |
|
| 2003 |
Iyasere C, Tilton JC, Johnson AJ, Younes S, Yassine-Diab B, Sekaly RP, Kwok WW, Migueles SA, Laborico AC, Shupert WL, Hallahan CW, Davey RT, Dybul M, Vogel S, Metcalf J, et al. Diminished proliferation of human immunodeficiency virus-specific CD4+ T cells is associated with diminished interleukin-2 (IL-2) production and is recovered by exogenous IL-2. Journal of Virology. 77: 10900-9. PMID 14512540 DOI: 10.1128/Jvi.77.20.10900-10909.2003 |
0.407 |
|
| 2003 |
Poulin JF, Sylvestre M, Champagne P, Dion ML, Kettaf N, Dumont A, Lainesse M, Fontaine P, Roy DC, Perreault C, Sékaly RP, Cheynier R. Evidence for adequate thymic function but impaired naive T-cell survival following allogeneic hematopoietic stem cell transplantation in the absence of chronic graft-versus-host disease. Blood. 102: 4600-7. PMID 12933579 DOI: 10.1182/Blood-2003-05-1428 |
0.413 |
|
| 2003 |
Bernardin F, Doukhan L, Longone-Miller A, Champagne P, Sekaly R, Delwart E. Estimate of the total number of CD8+ clonal expansions in healthy adults using a new DNA heteroduplex-tracking assay for CDR3 repertoire analysis. Journal of Immunological Methods. 274: 159-75. PMID 12609542 DOI: 10.1016/S0022-1759(02)00514-8 |
0.306 |
|
| 2003 |
Boyer JD, Kutzler MA, Chattergoon MA, Calarota SA, Pavlakis G, Sekaly RP, MacGregor RR, Weiner DB. Engineering DNA vaccination as an approach to HIV immune therapy Clinical and Applied Immunology Reviews. 3: 183-197. DOI: 10.1016/S1529-1049(02)00158-7 |
0.301 |
|
| 2002 |
Ellefsen K, Harari A, Champagne P, Bart P, Sékaly R, Pantaleo G. Distribution and functional analysis of memory antiviral CD8 T cell responses in HIV-1 and cytomegalovirus infections. European Journal of Immunology. 32: 3756-3764. PMID 12516570 DOI: 10.1002/1521-4141(200212)32:12<3756::Aid-Immu3756>3.0.Co;2-E |
0.49 |
|
| 2002 |
Moldovan MC, Yachou A, Lévesque K, Wu H, Hendrickson WA, Cohen EA, Sékaly RP. CD4 dimers constitute the functional component required for T cell activation Journal of Immunology. 169: 6261-6268. PMID 12444132 DOI: 10.4049/Jimmunol.169.11.6261 |
0.423 |
|
| 2002 |
Nie Z, Phenix BN, Lum JJ, Alam A, Lynch DH, Beckett B, Krammer PH, Sekaly RP, Badley AD. HIV-1 protease processes procaspase 8 to cause mitochondrial release of cytochrome c, caspase cleavage and nuclear fragmentation Cell Death and Differentiation. 9: 1172-1184. PMID 12404116 DOI: 10.1038/Sj.Cdd.4401094 |
0.3 |
|
| 2001 |
Champagne P, Dumont AR, Sékaly RP. Learning to remember: generation and maintenance of T-cell memory. Dna and Cell Biology. 20: 745-60. PMID 11879568 DOI: 10.1089/104454901753438561 |
0.366 |
|
| 2001 |
Lavoie PM, McGrath H, Shoukry NH, Cazenave PA, Sékaly RA, Thibodeau J. Quantitative relationship between MHC class II-superantigen complexes and the balance of T cell activation versus death Journal of Immunology. 166: 7229-7237. PMID 11390471 DOI: 10.4049/Jimmunol.166.12.7229 |
0.375 |
|
| 2001 |
Champagne P, Ogg GS, King AS, Knabenhans C, Ellefsen K, Nobile M, Appay V, Rizzardi GP, Fleury S, Lipp M, Förster R, Rowland-Jones S, Sékaly RP, McMichael AJ, Pantaleo G. Skewed maturation of memory HIV-specific CD8 T lymphocytes. Nature. 410: 106-11. PMID 11242051 DOI: 10.1038/35065118 |
0.334 |
|
| 2001 |
Cameron TO, Cochran JR, Yassine-Diab B, Sékaly RP, Stern LJ. Cutting edge: detection of antigen-specific CD4+ T cells by HLA-DR1 oligomers is dependent on the T cell activation state. Journal of Immunology (Baltimore, Md. : 1950). 166: 741-5. PMID 11145645 DOI: 10.4049/Jimmunol.166.2.741 |
0.437 |
|
| 2000 |
Gratton S, Haughn L, Sekaly RP, Julius M. The extracellular domain of CD4 regulates the initiation of T cell activation Molecular Immunology. 37: 213-219. PMID 10930628 DOI: 10.1016/S0161-5890(00)00046-8 |
0.4 |
|
| 2000 |
Al-Harthi L, Marchetti G, Steffens CM, Poulin J, Sékaly R, Landay A. Detection of T cell receptor circles (TRECs) as biomarkers for de novo T cell synthesis using a quantitative polymerase chain reaction-enzyme linked immunosorbent assay (PCR-ELISA). Journal of Immunological Methods. 237: 187-97. PMID 10725462 DOI: 10.1016/S0022-1759(00)00136-8 |
0.427 |
|
| 2000 |
Soudeyns H, Champagne P, Holloway CL, Silvestri GU, Ringuette N, Samson J, Lapointe N, Sékaly RP. Transient T cell receptor β-chain variable region-specific expansions of CD4+ and CD8+ T cells during the early phase of pediatric human immunodeficiency virus infection: Characterization of expanded cell populations by T cell receptor phenotyping Journal of Infectious Diseases. 181: 107-120. PMID 10608757 DOI: 10.1086/315181 |
0.398 |
|
| 2000 |
Routy J, Vanhems P, Rouleau D, Tsoukas C, Lefèbvre E, Côté P, LeBlanc R, Conway B, Alary M, Bruneau J, Sekaly R. Comparison of Clinical Features of Acute HIV-1 Infection in Patients Infected Sexually or Through Injection Drug Use. Journal of Acquired Immune Deficiency Syndromes. 24: 425-432. DOI: 10.1097/00042560-200008150-00004 |
0.322 |
|
| 1999 |
Alam A, Cohen LY, Aouad S, Sékaly R. Early activation of caspases during T lymphocyte stimulation results in selective substrate cleavage in nonapoptotic cells. Journal of Experimental Medicine. 190: 1879-1890. PMID 10601362 DOI: 10.1084/Jem.190.12.1879 |
0.381 |
|
| 1999 |
Yachou A, Sékaly RP. Binding of soluble recombinant HIV envelope glycoprotein, rgp120, induces conformational changes in the cellular membrane-anchored CD4 molecule. Biochemical and Biophysical Research Communications. 265: 428-33. PMID 10558884 DOI: 10.1006/Bbrc.1999.1686 |
0.372 |
|
| 1999 |
Poulin JF, Sékaly RP. Function of the thymus in HIV-infected adults. Jama. 282: 219. PMID 10422975 DOI: 10.1001/Jama.282.3.219 |
0.496 |
|
| 1999 |
Lavoie PM, Thibodeau J, Erard F, Sékaly RP. Understanding the mechanism of action of bacterial superantigens from a decade of research Immunological Reviews. 168: 257-269. PMID 10399079 DOI: 10.1111/J.1600-065X.1999.Tb01297.X |
0.39 |
|
| 1998 |
Leder L, Llera A, Lavoie PM, Lebedeva MI, Li H, Sékaly RP, Bohach GA, Gahr PJ, Schlievert PM, Karjalainen K, Mariuzza RA. A mutational analysis of the binding of staphylococcal enterotoxins B and C3 to the T cell receptor β chain and major histocompatibility complex class II Journal of Experimental Medicine. 187: 823-833. PMID 9500785 DOI: 10.1084/Jem.187.6.823 |
0.348 |
|
| 1998 |
Pantaleo G, Soudeyns H, Demarest JF, Vaccarezza M, Graziosi C, Paolucci S, Daucher MB, Cohen OJ, Denis F, Biddison WE, Sekaly RP, Fauci AS. Accumulation of human immunodeficiency virus-specific cytotoxic T lymphocytes away from the predominant site of virus replication during primary infection. European Journal of Immunology. 27: 3166-73. PMID 9464802 DOI: 10.1002/eji.1830271213 |
0.33 |
|
| 1998 |
Ciurli C, Posnett DN, Sékaly R, Denis F. Highly biased CDR3 usage in restricted sets of beta chain variable regions during viral superantigen 9 response. Journal of Experimental Medicine. 187: 253-258. PMID 9432983 DOI: 10.1084/Jem.187.2.253 |
0.399 |
|
| 1997 |
Alam A, Braun MY, Hartgers F, Lesage S, Cohen L, Hugo P, Denis F, Sékaly RP. Specific activation of the cysteine protease CPP32 during the negative selection of T cells in the thymus Journal of Experimental Medicine. 186: 1503-1512. PMID 9348308 DOI: 10.1084/Jem.186.9.1503 |
0.369 |
|
| 1997 |
Pantaleo G, Soudeyns H, Demarest JF, Vaccarezza M, Graziosi C, Paolucci S, Daucher M, Cohen OJ, Denis F, Biddison WE, Sekaly RP, Fauci AS. Evidence for rapid disappearance of initially expanded HIV-specific CD8+ T cell clones during primary HIV infection. Proceedings of the National Academy of Sciences of the United States of America. 94: 9848-53. PMID 9275214 DOI: 10.1073/Pnas.94.18.9848 |
0.399 |
|
| 1997 |
Delcourt M, Thibodeau J, Denis F, Sekaly RP. Paracrine transfer of mouse mammary tumor virus superantigen. The Journal of Experimental Medicine. 185: 471-80. PMID 9053447 DOI: 10.1084/Jem.185.3.471 |
0.339 |
|
| 1997 |
De Alba YB, Marche PN, Cazenave PA, Cloutier I, Sekaly RP, Thibodeau J. Vα domain modulates the multiple topologies of mouse T cell receptor vβ20/staphylococcal enterotoxins A and E complexes European Journal of Immunology. 27: 92-99. PMID 9022003 DOI: 10.1002/Eji.1830270114 |
0.376 |
|
| 1996 |
Sutkowski N, Palkama T, Ciurli C, Sekaly RP, Thorley-Lawson DA, Huber BT. An Epstein-Barr virus-associated superantigen Journal of Experimental Medicine. 184: 971-980. PMID 9064357 DOI: 10.1084/Jem.184.3.971 |
0.355 |
|
| 1996 |
Ciurli C, Sékaly R, Soudeyns H. Study of the T cell receptor repertoire in viral immunodeficiency disease. Springer Seminars in Immunopathology. 17: 319-332. PMID 8966659 DOI: 10.1007/Bf01795132 |
0.499 |
|
| 1996 |
Filion MC, Proulx C, Bradley AJ, Devine DV, Sékaly RP, Décary F, Chartrand P. Presence in peripheral blood of healthy individuals of autoreactive T cells to a membrane antigen present on bone marrow-derived cells Blood. 88: 2144-2150. PMID 8822934 |
0.327 |
|
| 1996 |
Filion M, Proulx C, Bradley A, Devine D, Sekaly R, Decary F, Chartrand P. Presence in peripheral blood of healthy individuals of autoreactive T cells to a membrane antigen present on bone marrow-derived cells Blood. 88: 2144-2150. DOI: 10.1182/Blood.V88.6.2144.Bloodjournal8862144 |
0.433 |
|
| 1994 |
Zerbib AC, Reske-Kunz AB, Lock P, Sékaly RP. CD4-mediated enhancement or inhibition of T cell activation does not require the CD4:p56lck association. The Journal of Experimental Medicine. 179: 1973-83. PMID 8195720 DOI: 10.1084/jem.179.6.1973 |
0.316 |
|
| 1994 |
Graziosi C, Pantaleo G, Gantt KR, Fortin JP, Demarest JF, Cohen OJ, Sékaly RP, Fauci AS. Lack of evidence for the dichotomy of TH1 and TH2 predominance in HIV-infected individuals. Science (New York, N.Y.). 265: 248-52. PMID 8023143 DOI: 10.1126/Science.8023143 |
0.425 |
|
| 1994 |
Rebai N, Pantaleo G, Demarest JF, Ciurli C, Soudeyns H, Adelsberger JW, Vaccarezza M, Walker RE, Sekaly RP, Fauci AS. Analysis of the T-cell receptor β-chain variable-region (Vβ) repertoire in monozygotic twins discordant for human immunodeficiency virus: Evidence for perturbations of specific Vβ segments in CD4+ T cells of the virus-positive twins Proceedings of the National Academy of Sciences of the United States of America. 91: 1529-1533. PMID 7906416 DOI: 10.1073/Pnas.91.4.1529 |
0.342 |
|
| 1994 |
Tremblay M, Meloche S, Gratton S, Wainberg M, Sékaly R. Association of p56lck with the cytoplasmic domain of CD4 modulates HIV-1 expression. The Embo Journal. 13: 774-783. DOI: 10.1002/J.1460-2075.1994.Tb06320.X |
0.346 |
|
| 1993 |
Labrecque N, McGrath H, Subramanyam M, Huber BT, Sekaly RP. Human T cells respond to mouse mammary tumor virus-encoded superantigen: Vβ restriction and conserved evolutionary features Journal of Experimental Medicine. 177: 1735-1743. PMID 8388432 DOI: 10.1084/Jem.177.6.1735 |
0.313 |
|
| 1993 |
Soudeyns H, Rebai N, Pantaleo GP, Ciurli C, Boghossian T, Sékaly R, Fauci AS. The T cell receptor Vβ repertoire in HIV-1 infection and disease Seminars in Immunology. 5: 175-185. PMID 8102262 DOI: 10.1006/Smim.1993.1021 |
0.416 |
|
| 1992 |
Haughn L, Gratton S, Caron L, Sékaly RP, Veillette A, Julius M. Association of tyrosine kinase p56lck with CD4 inhibits the induction of growth through the alpha beta T-cell receptor. Nature. 358: 328-31. PMID 1322497 DOI: 10.1038/358328A0 |
0.422 |
|
| 1991 |
Sekaly RP, Croteau G, Bowman M, Scholl P, Burakoff S, Geha RS. The CD4 molecule is not always required for the T cell response to bacterial enterotoxins Journal of Experimental Medicine. 173: 367-371. PMID 1988539 DOI: 10.1084/Jem.173.2.367 |
0.332 |
|
| 1991 |
Carrel S, Salvi S, Rafti F, Favrot M, Rapin C, Sekaly RP. Direct involvement of CD7 (gp40) in activation of TcR γ/δ+ T cells European Journal of Immunology. 21: 1195-1200. PMID 1709867 DOI: 10.1002/Eji.1830210515 |
0.3 |
|
| 1991 |
Biassoni R, Ferrini S, Prigione I, Pelak VS, Sekaly RP, Long EO. Activated CD3- CD16+ natural killer cells express a subset of the lymphokine genes induced in activated αβ+ and γδ+ T cells Scandinavian Journal of Immunology. 33: 247-252. PMID 1707180 DOI: 10.1111/j.1365-3083.1991.tb01769.x |
0.309 |
|
| 1990 |
Tremblay M, Meloche S, Sekaly RP, Wainberg MA. Complement receptor 2 mediates enhancement of human immunodeficiency virus 1 infection in epstein-barr virus-carrying B cells Journal of Experimental Medicine. 171: 1791-1796. PMID 2159052 DOI: 10.1084/Jem.171.5.1791 |
0.315 |
|
| 1990 |
Kanagawa O, Nakauchi H, Sekaly RP, Maeda K, Takagaki Y. Expression and function of the tranfected CD8α chain in murine T cell hybridomas International Immunology. 2: 957-964. PMID 2127694 DOI: 10.1093/Intimm/2.10.957 |
0.338 |
|
| 1987 |
Gay D, Maddon P, Sekaly R, Talle MA, Godfrey M, Long E, Goldstein G, Chess L, Axel R, Kappler J. Functional interaction between human T-cell protein CD4 and the major histocompatibility complex HLA-DR antigen. Nature. 328: 626-9. PMID 3112582 DOI: 10.1038/328626A0 |
0.318 |
|
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