Aloysius Klingelhutz - Publications

Affiliations: 
University of Iowa, Iowa City, IA 
Area:
Molecular Biology, Cell Biology

33 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Bullert A, Li X, Zhang C, Lee K, Pulliam CF, Cagle BS, Doorn JA, Klingelhutz AJ, Robertson LW, Lehmler HJ. Disposition and Metabolomic Effects of 2,2',5,5'-Tetrachlorobiphenyl in Female Rats Following Intraperitoneal Exposure. Biorxiv : the Preprint Server For Biology. PMID 37609242 DOI: 10.1101/2023.06.19.544952  0.437
2023 Bullert A, Li X, Chunyun Z, Lee K, Pulliam CF, Cagle BS, Doorn JA, Klingelhutz AJ, Robertson LW, Lehmler HJ. Disposition and Metabolomic Effects of 2,2',5,5'-Tetrachlorobiphenyl in Female Rats Following Intraperitoneal Exposure. Environmental Toxicology and Pharmacology. 104245. PMID 37572994 DOI: 10.1016/j.etap.2023.104245  0.437
2022 Gourronc FA, Helm BK, Robertson LW, Chimenti MS, Lehmler HJ, Ankrum JA, Klingelhutz AJ. Dataset of transcriptomic changes that occur in human preadipocytes over a 3-day course of exposure to 3,3',4,4',5-Pentachlorobiphenyl (PCB126). Data in Brief. 45: 108571. PMID 36131953 DOI: 10.1016/j.dib.2022.108571  0.525
2022 Gourronc FA, Helm BK, Robertson LW, Chimenti MS, Joachim-Lehmler H, Ankrum JA, Klingelhutz AJ. Transcriptome sequencing of 3,3',4,4',5-Pentachlorobiphenyl (PCB126)-treated human preadipocytes demonstrates progressive changes in pathways associated with inflammation and diabetes. Toxicology in Vitro : An International Journal Published in Association With Bibra. 83: 105396. PMID 35618242 DOI: 10.1016/j.tiv.2022.105396  0.508
2019 Gourronc FA, Perdew GH, Robertson LW, Klingelhutz AJ. PCB126 blocks the thermogenic beiging response of adipocytes. Environmental Science and Pollution Research International. PMID 31721030 DOI: 10.1007/S11356-019-06663-0  0.484
2017 Gourronc FA, Robertson LW, Klingelhutz AJ. A delayed proinflammatory response of human preadipocytes to PCB126 is dependent on the aryl hydrocarbon receptor. Environmental Science and Pollution Research International. PMID 28699004 DOI: 10.1007/S11356-017-9676-Z  0.489
2016 Gadupudi GS, Klingelhutz AJ, Robertson LW. Diminished phosphorylation of CREB is a key event in the dysregulation of gluconeogenesis and glycogenolysis in PCB126 hepatotoxicity. Chemical Research in Toxicology. PMID 27509375 DOI: 10.1021/Acs.Chemrestox.6B00172  0.731
2015 Gadupudi GS, Klaren WD, Olivier AK, Klingelhutz AJ, Robertson LW. PCB126-induced disruption in gluconeogenesis and fatty acid oxidation precedes fatty liver in male rats. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 26396156 DOI: 10.1093/Toxsci/Kfv215  0.726
2015 Gadupudi G, Gourronc FA, Ludewig G, Robertson LW, Klingelhutz AJ. PCB126 inhibits adipogenesis of human preadipocytes. Toxicology in Vitro : An International Journal Published in Association With Bibra. 29: 132-41. PMID 25304490 DOI: 10.1016/J.Tiv.2014.09.015  0.742
2014 Hagen J, Muniz VP, Falls KC, Reed SM, Taghiyev AF, Quelle FW, Gourronc FA, Klingelhutz AJ, Major HJ, Askeland RW, Sherman SK, O'Dorisio TM, Bellizzi AM, Howe JR, Darbro BW, et al. RABL6A promotes G1-S phase progression and pancreatic neuroendocrine tumor cell proliferation in an Rb1-dependent manner. Cancer Research. 74: 6661-70. PMID 25273089 DOI: 10.1158/0008-5472.Can-13-3742  0.606
2013 Pereboeva L, Westin E, Patel T, Flaniken I, Lamb L, Klingelhutz A, Goldman F. DNA damage responses and oxidative stress in dyskeratosis congenita. Plos One. 8: e76473. PMID 24124565 DOI: 10.1182/Blood.V120.21.2359.2359  0.725
2011 Senthilkumar PK, Klingelhutz AJ, Jacobus JA, Lehmler H, Robertson LW, Ludewig G. Airborne polychlorinated biphenyls (PCBs) reduce telomerase activity and shorten telomere length in immortal human skin keratinocytes (HaCat). Toxicology Letters. 204: 64-70. PMID 21530622 DOI: 10.1016/J.Toxlet.2011.04.012  0.51
2011 Westin ER, Aykin-Burns N, Buckingham EM, Spitz DR, Goldman FD, Klingelhutz AJ. The p53/p21(WAF/CIP) pathway mediates oxidative stress and senescence in dyskeratosis congenita cells with telomerase insufficiency. Antioxidants & Redox Signaling. 14: 985-97. PMID 21087144 DOI: 10.1089/Ars.2010.3444  0.72
2009 Nowicki P, Hoover A, De Geest K, Goodheart M, Lace M, Haugen T, Turek L, Strand G, Bossler A, Klingelhutz A, Lee J. Protein tyrosine phosphatase nonreceptor 13 (PTPN13) is targeted by human papillomavirus 16 E6 in cervical epithelium Infectious Agents and Cancer. 4. DOI: 10.1186/1750-9378-4-S2-P31  0.318
2009 Hoover A, Strand G, Nowicki P, Anderson M, Klingelhutz A, Bossler A, Lee J. An invasion mechanism for human papillomavirus related cancers: HPV 16 E6 degrades PTPN13 allowing enhanced map kinase signaling Infectious Agents and Cancer. 4: 1-1. DOI: 10.1186/1750-9378-4-S2-O13  0.386
2009 Agarwal S, Loh Y, McLoughlin EM, Huang J, Park I, Miller JD, Huo H, Okuka M, Reis RMd, Loewer S, Keefe D, Goldman FD, Klingelhutz A, Liu L, Daley GQ. Telomere Elongation in Dyskeratosis Congenita Induced Pluripotent Stem Cells. Blood. 114: 497-497. DOI: 10.1182/Blood.V114.22.497.497  0.39
2008 Jacobus JA, Flor S, Klingelhutz A, Robertson LW, Ludewig G. 2-(4'-CHLOROPHENYL)-1,4-BENZOQUINONE INCREASES THE FREQUENCY OF MICRONUCLEI AND SHORTENS TELOMERES. Environmental Toxicology and Pharmacology. 25: 267-272. PMID 18438462 DOI: 10.1016/J.Etap.2007.10.022  0.514
2008 Goldman FD, Cowan KR, Tawfik DS, Hamilton W, Westin E, Klingelhutz A. Transduction of hTR into Hematopoietic Stem Cells Increases Telomerase Activity Blood. 112: 4624-4624. DOI: 10.1182/Blood.V112.11.4624.4624  0.744
2007 Westin ER, Chavez E, Lee KM, Gourronc FA, Riley S, Lansdorp PM, Goldman FD, Klingelhutz AJ. Telomere restoration and extension of proliferative lifespan in dyskeratosis congenita fibroblasts. Aging Cell. 6: 383-94. PMID 17381549 DOI: 10.1111/J.1474-9726.2007.00288.X  0.716
2007 Witt T, Klingelhutz A, Westin E, Satyanarayana P, Lansdorp PM, Goldman FD. The Impact of Telomere Shortening in Dyskeratosis Congenita Cells on DNA Damage Response Pathways. Blood. 110: 4052-4052. DOI: 10.1182/Blood.V110.11.4052.4052  0.396
2006 Berger KL, Barriga F, Lace MJ, Turek LP, Zamba GJ, Domann FE, Lee JH, Klingelhutz AJ. Cervical keratinocytes containing stably replicating extrachromosomal HPV-16 are refractory to transformation by oncogenic H-Ras. Virology. 356: 68-78. PMID 16945398 DOI: 10.1016/J.Virol.2006.07.039  0.726
2006 Nyunoya T, Monick MM, Klingelhutz A, Yarovinsky TO, Cagley JR, Hunninghake GW. Cigarette smoke induces cellular senescence. American Journal of Respiratory Cell and Molecular Biology. 35: 681-8. PMID 16840774 DOI: 10.1165/Rcmb.2006-0169Oc  0.305
2006 Darbro BW, Lee KM, Nguyen NK, Domann FE, Klingelhutz AJ. Methylation of the p16(INK4a) promoter region in telomerase immortalized human keratinocytes co-cultured with feeder cells. Oncogene. 25: 7421-33. PMID 16767161 DOI: 10.1038/Sj.Onc.1209729  0.612
2005 Darbro BW, Schneider GB, Klingelhutz AJ. Co-regulation of p16INK4A and migratory genes in culture conditions that lead to premature senescence in human keratinocytes. The Journal of Investigative Dermatology. 125: 499-509. PMID 16117791 DOI: 10.1111/J.0022-202X.2005.23844.X  0.629
2005 Klingelhutz AJ, Qian Q, Phillips SL, Gourronc FA, Darbro BW, Patil SR. Amplification of the chromosome 20q region is associated with expression of HPV-16 E7 in human airway and anogenital epithelial cells. Virology. 340: 237-44. PMID 16051300 DOI: 10.1016/J.Virol.2005.06.027  0.596
2004 Lee JH, Yi SM, Anderson ME, Berger KL, Welsh MJ, Klingelhutz AJ, Ozbun MA. Propagation of infectious human papillomavirus type 16 by using an adenovirus and Cre/LoxP mechanism. Proceedings of the National Academy of Sciences of the United States of America. 101: 2094-9. PMID 14769917 DOI: 10.1073/Pnas.0308615100  0.726
2003 Palanca-Wessels MC, Klingelhutz A, Reid BJ, Norwood TH, Opheim KE, Paulson TG, Feng Z, Rabinovitch PS. Extended lifespan of Barrett's esophagus epithelium transduced with the human telomerase catalytic subunit: a useful in vitro model. Carcinogenesis. 24: 1183-90. PMID 12807723 DOI: 10.1093/Carcin/Bgg076  0.354
2002 Mauser A, Holley-Guthrie E, Zanation A, Yarborough W, Kaufmann W, Klingelhutz A, Seaman WT, Kenney S. The Epstein-Barr virus immediate-early protein BZLF1 induces expression of E2F-1 and other proteins involved in cell cycle progression in primary keratinocytes and gastric carcinoma cells. Journal of Virology. 76: 12543-52. PMID 12438580 DOI: 10.1128/Jvi.76.24.12543-12552.2002  0.393
2002 Sprague DL, Phillips SL, Mitchell CJ, Berger KL, Lace M, Turek LP, Klingelhutz AJ. Telomerase activation in cervical keratinocytes containing stably replicating human papillomavirus type 16 episomes. Virology. 301: 247-54. PMID 12359427 DOI: 10.1006/Viro.2002.1542  0.732
2001 Duffy C, Klingelhutz A. Oligonucleotide array analysis of telomerase activation by the human papillomavirus type 16 E6 protein Nature Genetics. 27: 51-51. DOI: 10.1038/87062  0.308
2000 Farwell DG, Shera KA, Koop JI, Bonnet GA, Matthews CP, Reuther GW, Coltrera MD, McDougall JK, Klingelhutz AJ. Genetic and epigenetic changes in human epithelial cells immortalized by telomerase. The American Journal of Pathology. 156: 1537-47. PMID 10793065 DOI: 10.1016/S0002-9440(10)65025-0  0.317
1998 Kiyono T, Foster SA, Koop JI, McDougall JK, Galloway DA, Klingelhutz AJ. Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells. Nature. 396: 84-8. PMID 9817205 DOI: 10.1038/23962  0.305
1995 Galloway DA, Halbert CL, Demers GW, Foster SA, Blanton RA, Merrick D, Klingelhutz A, McDougall JK. Use of amphotropic retroviruses expressing human papillomavirus 16 E6 and E7 to determine the consequences of acute expression of the viral oncogenes and to establish immortalized human cell lines Radiation Oncology Investigations. 3: 315-319. DOI: 10.1002/Roi.2970030612  0.404
Show low-probability matches.