| Year |
Citation |
Score |
| 2017 |
Ijaz T, Sun H, Pinchuk IV, Milewicz DM, Tilton RG, Brasier AR. Deletion of NF-κB/RelA in Angiotensin II-Sensitive Mesenchymal Cells Blocks Aortic Vascular Inflammation and Abdominal Aortic Aneurysm Formation. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 28818856 DOI: 10.1161/Atvbaha.117.309863 |
0.306 |
|
| 2017 |
Ijaz T, Jamaluddin M, Zhao Y, Zhang Y, Jay J, Finnerty CC, Herndon DN, Tilton RG, Brasier AR. Coordinate activities of BRD4 and CDK9 in the transcriptional elongation complex are required for TGFβ-induced Nox4 expression and myofibroblast transdifferentiation. Cell Death & Disease. 8: e2606. PMID 28182006 DOI: 10.1038/Cddis.2016.434 |
0.324 |
|
| 2016 |
Ijaz T, Tilton RG, Brasier AR. Cytokine amplification and macrophage effector functions in aortic inflammation and abdominal aortic aneurysm formation. Journal of Thoracic Disease. 8: E746-54. PMID 27619163 DOI: 10.21037/Jtd.2016.06.37 |
0.336 |
|
| 2015 |
Hu S, Liu H, Ha Y, Luo X, Motamedi M, Gupta MP, Ma JX, Tilton RG, Zhang W. Posttranslational modification of Sirt6 activity by peroxynitrite. Free Radical Biology & Medicine. 79: 176-85. PMID 25476852 DOI: 10.1016/J.Freeradbiomed.2014.11.011 |
0.359 |
|
| 2015 |
Boretsky A, Gupta P, Tirgan N, Liu R, Godley BF, Zhang W, Tilton RG, Motamedi M. Nicotine accelerates diabetes-induced retinal changes. Current Eye Research. 40: 368-77. PMID 24911405 DOI: 10.3109/02713683.2014.924147 |
0.307 |
|
| 2014 |
Liu R, Liu H, Ha Y, Tilton RG, Zhang W. Oxidative Stress Induces Endothelial Cell Senescence via Downregulation of Sirt6 Biomed Research International. 2014: 902842-902842. PMID 25162034 DOI: 10.1155/2014/902842 |
0.431 |
|
| 2014 |
Ameri H, Liu H, Liu R, Ha Y, Paulucci-Holthauzen AA, Hu S, Motamedi M, Godley BF, Tilton RG, Zhang W. TWEAK/Fn14 pathway is a novel mediator of retinal neovascularization. Investigative Ophthalmology & Visual Science. 55: 801-13. PMID 24408972 DOI: 10.1167/Iovs.13-12812 |
0.305 |
|
| 2013 |
Ju X, Ijaz T, Sun H, Ray S, Lejeune W, Lee C, Recinos A, Guo DC, Milewicz DM, Tilton RG, Brasier AR. Interleukin-6-signal transducer and activator of transcription-3 signaling mediates aortic dissections induced by angiotensin II via the T-helper lymphocyte 17-interleukin 17 axis in C57BL/6 mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 33: 1612-21. PMID 23685554 DOI: 10.1161/Atvbaha.112.301049 |
0.322 |
|
| 2012 |
Tirgan N, Kulp GA, Gupta P, Boretsky A, Wiraszka TA, Godley B, Tilton RG, Motamedi M. Nicotine exposure exacerbates development of cataracts in a type 1 diabetic rat model. Experimental Diabetes Research. 2012: 349320. PMID 23049540 DOI: 10.1155/2012/349320 |
0.342 |
|
| 2012 |
Starkey JM, Tilton RG. Proteomics and systems biology for understanding diabetic nephropathy Journal of Cardiovascular Translational Research. 5: 479-490. PMID 22581264 DOI: 10.1007/S12265-012-9372-9 |
0.319 |
|
| 2011 |
Zhao Y, Banerjee S, LeJeune WS, Choudhary S, Tilton RG. NF-κB-inducing kinase increases renal tubule epithelial inflammation associated with diabetes. Experimental Diabetes Research. 2011: 192564-192564. PMID 21869881 DOI: 10.1155/2011/192564 |
0.392 |
|
| 2011 |
Zhao Y, Banerjee S, Dey N, LeJeune WS, Sarkar PS, Brobey R, Rosenblatt KP, Tilton RG, Choudhary S. Klotho depletion contributes to increased inflammation in kidney of the db/db mouse model of diabetes via RelA (serine)536 phosphorylation. Diabetes. 60: 1907-16. PMID 21593200 DOI: 10.2337/Db10-1262 |
0.38 |
|
| 2011 |
Tieu BC, Ju X, Lee C, Sun H, Lejeune W, Recinos A, Brasier AR, Tilton RG. Aortic adventitial fibroblasts participate in angiotensin-induced vascular wall inflammation and remodeling. Journal of Vascular Research. 48: 261-72. PMID 21099231 DOI: 10.1159/000320358 |
0.346 |
|
| 2010 |
Starkey JM, Zhao Y, Sadygov RG, Haidacher SJ, Lejeune WS, Dey N, Luxon BA, Kane MA, Napoli JL, Denner L, Tilton RG. Altered retinoic acid metabolism in diabetic mouse kidney identified by O isotopic labeling and 2D mass spectrometry. Plos One. 5: e11095. PMID 20559430 DOI: 10.1371/Journal.Pone.0011095 |
0.375 |
|
| 2010 |
Westenbrink BD, Ruifrok WPT, Voors AA, Tilton RG, Veldhuisen DJV, Schoemaker RG, Gilst WHV, Boer RAD. Vascular endothelial growth factor is crucial for erythropoietin-induced improvement of cardiac function in heart failure. Cardiovascular Research. 87: 30-39. PMID 20139114 DOI: 10.1093/Cvr/Cvq041 |
0.363 |
|
| 2010 |
Ido Y, Nyengaard JR, Chang K, Tilton RG, Kilo C, Mylari BL, Oates PJ, Williamson JR. Early neural and vascular dysfunctions in diabetic rats are largely sequelae of increased sorbitol oxidation. Antioxidants & Redox Signaling. 12: 39-51. PMID 19624259 DOI: 10.1089/Ars.2009.2502 |
0.327 |
|
| 2009 |
Tieu BC, Lee C, Sun H, Lejeune W, Recinos A, Ju X, Spratt H, Guo DC, Milewicz D, Tilton RG, Brasier AR. An adventitial IL-6/MCP1 amplification loop accelerates macrophage-mediated vascular inflammation leading to aortic dissection in mice. The Journal of Clinical Investigation. 119: 3637-51. PMID 19920349 DOI: 10.1172/Jci38308 |
0.341 |
|
| 2009 |
Irani Y, Brereton HM, Tilton RG, Coster DJ, Williams KA. Production of scFv antibody fragments from a hybridoma with functional activity against human vascular endothelial growth factor. Hybridoma (2005). 28: 205-9. PMID 19445630 DOI: 10.1089/Hyb.2009.0001 |
0.367 |
|
| 2008 |
Hou T, Tieu BC, Ray S, Recinos Iii A, Cui R, Tilton RG, Brasier AR. Roles of IL-6-gp130 Signaling in Vascular Inflammation. Current Cardiology Reviews. 4: 179-92. PMID 19936194 DOI: 10.2174/157340308785160570 |
0.332 |
|
| 2008 |
Westenbrink BD, Ruifrok WP, Boer RAD, Voors AA, Tilton R, Veldhuisen DJV, Schoemaker RG, Gilst WHV. 588 Erythropoietin restores cardiac function in Heart Failure by promoting Vascular Endothelial Growth Factor expression in cardiomyocytes European Journal of Heart Failure Supplements. 7: 147-148. DOI: 10.1016/S1567-4215(08)60422-1 |
0.304 |
|
| 2007 |
Tilton RG, Haidacher SJ, Lejeune WS, Zhang X, Zhao Y, Kurosky A, Brasier AR, Denner L. Diabetes-induced changes in the renal cortical proteome assessed with two-dimensional gel electrophoresis and mass spectrometry. Proteomics. 7: 1729-42. PMID 17436268 DOI: 10.1002/Pmic.200700017 |
0.362 |
|
| 2007 |
Recinos A, LeJeune WS, Sun H, Lee CY, Tieu BC, Lu M, Hou T, Boldogh I, Tilton RG, Brasier AR. Angiotensin II induces IL-6 expression and the Jak-STAT3 pathway in aortic adventitia of LDL receptor-deficient mice. Atherosclerosis. 194: 125-33. PMID 17109863 DOI: 10.1016/J.Atherosclerosis.2006.10.013 |
0.327 |
|
| 2006 |
Cui R, Tieu B, Recinos A, Tilton RG, Brasier AR. RhoA mediates angiotensin II-induced phospho-Ser536 nuclear factor kappaB/RelA subunit exchange on the interleukin-6 promoter in VSMCs. Circulation Research. 99: 723-30. PMID 16960103 DOI: 10.1161/01.Res.0000244015.10655.3F |
0.353 |
|
| 2006 |
Vriese ASD, Tilton RG, Mortier S, Lameire NH. Myofibroblast transdifferentiation of mesothelial cells is mediated by RAGE and contributes to peritoneal fibrosis in uraemia Nephrology Dialysis Transplantation. 21: 2549-2555. PMID 16757496 DOI: 10.1093/Ndt/Gfl271 |
0.324 |
|
| 2006 |
Starkey JM, Haidacher SJ, LeJeune WS, Zhang X, Tieu BC, Choudhary S, Brasier AR, Denner LA, Tilton RG. Diabetes-induced activation of canonical and noncanonical nuclear factor-kappaB pathways in renal cortex. Diabetes. 55: 1252-9. PMID 16644679 DOI: 10.2337/Db05-1554 |
0.381 |
|
| 2006 |
Jensen LJ, Denner L, Schrijvers BF, Tilton RG, Rasch R, Flyvbjerg A. Renal effects of a neutralising RAGE-antibody in long-term streptozotocin-diabetic mice. The Journal of Endocrinology. 188: 493-501. PMID 16522729 DOI: 10.1677/Joe.1.06524 |
0.391 |
|
| 2006 |
Schrijvers BF, Flyvbjerg A, Tilton RG, Lameire NH, Vriese ASD. A neutralizing VEGF antibody prevents glomerular hypertrophy in a model of obese type 2 diabetes, the Zucker diabetic fatty rat Nephrology Dialysis Transplantation. 21: 324-329. PMID 16249198 DOI: 10.1093/Ndt/Gfi217 |
0.42 |
|
| 2005 |
Schrijvers BF, Flyvbjerg A, Tilton RG, Rasch R, Lameire NH, De Vriese AS. Pathophysiological role of vascular endothelial growth factor in the remnant kidney. Nephron. Experimental Nephrology. 101: e9-15. PMID 15925906 DOI: 10.1159/000086034 |
0.369 |
|
| 2005 |
Schrijvers BF, Vriese ASD, Tilton R, Voorde JVD, Denner L, Lameire NH, Flyvbjerg A. Inhibition of vascular endothelial growth factor (VEGF) does not affect early renal changes in a rat model of lean type 2 diabetes. Hormone and Metabolic Research. 37: 21-25. PMID 15702434 DOI: 10.1055/S-2005-861027 |
0.433 |
|
| 2005 |
Fukuda G, Khan ZA, Barbin YP, Farhangkhoee H, Tilton RG, Chakrabarti S. Endothelin-mediated remodeling in aortas of diabetic rats. Diabetes/Metabolism Research and Reviews. 21: 367-75. PMID 15580650 DOI: 10.1002/Dmrr.527 |
0.399 |
|
| 2004 |
Flyvbjerg A, Denner L, Schrijvers BF, Tilton RG, Mogensen TH, Paludan SR, Rasch R. Long-term renal effects of a neutralizing RAGE antibody in obese type 2 diabetic mice. Diabetes. 53: 166-72. PMID 14693711 DOI: 10.2337/Diabetes.53.1.166 |
0.36 |
|
| 2002 |
Flyvbjerg A, Dagnaes-Hansen F, De Vriese AS, Schrijvers BF, Tilton RG, Rasch R. Amelioration of long-term renal changes in obese type 2 diabetic mice by a neutralizing vascular endothelial growth factor antibody. Diabetes. 51: 3090-4. PMID 12351452 DOI: 10.2337/Diabetes.51.10.3090 |
0.418 |
|
| 2002 |
Tilton RG. Diabetic vascular dysfunction: links to glucose-induced reductive stress and VEGF. Microscopy Research and Technique. 57: 390-407. PMID 12112445 DOI: 10.1002/Jemt.10092 |
0.429 |
|
| 2002 |
Flyvbjerg A, Schrijvers BF, De Vriese AS, Tilton RG, Rasch R. Compensatory glomerular growth after unilateral nephrectomy is VEGF dependent. American Journal of Physiology. Endocrinology and Metabolism. 283: E362-6. PMID 12110543 DOI: 10.1152/Ajpendo.00007.2002 |
0.364 |
|
| 2001 |
Vriese AS, Tilton RG, Stephan CC, Lameire NH. Vascular endothelial growth factor is essential for hyperglycemia-induced structural and functional alterations of the peritoneal membrane. Journal of the American Society of Nephrology : Jasn. 12: 1734-1741. PMID 11461947 DOI: 10.1681/ASN.V1281734 |
0.319 |
|
| 2001 |
Yeh CH, Sturgis L, Haidacher J, Zhang XN, Sherwood SJ, Bjercke RJ, Juhasz O, Crow MT, Tilton RG, Denner L. Requirement for p38 and p44/p42 mitogen-activated protein kinases in RAGE-mediated nuclear factor-kappaB transcriptional activation and cytokine secretion. Diabetes. 50: 1495-504. PMID 11375353 DOI: 10.2337/Diabetes.50.6.1495 |
0.34 |
|
| 2001 |
Vriese AS, Tilton RG, Elger M, Stephan CC, Kriz W, Lameire NH. Antibodies against vascular endothelial growth factor improve early renal dysfunction in experimental diabetes. Journal of the American Society of Nephrology : Jasn. 12: 993-1000. PMID 11316858 DOI: 10.1681/ASN.V125993 |
0.351 |
|
| 2001 |
Ido Y, Chang KC, Lejeune WS, Bjercke RJ, Reiser KM, Williamson JR, Tilton RG. Vascular dysfunction induced by AGE is mediated by VEGF via mechanisms involving reactive oxygen species, guanylate cyclase, and protein kinase C. Microcirculation. 8: 251-263. DOI: 10.1038/Sj.Mn.7800079 |
0.383 |
|
| 1998 |
Vanderslice P, Munsch CL, Rachal E, Erichsen D, Sughrue KM, Truong AN, Wygant JN, McIntyre BW, Eskin SG, Tilton RG, Polverini PJ. Angiogenesis induced by tumor necrosis factor-agr; is mediated by alpha4 integrins. Angiogenesis. 2: 265-75. PMID 14517466 DOI: 10.1023/A:1009296700991 |
0.331 |
|
| 1997 |
Tilton RG, Dixon RA, Brock TA. Growth factor antagonists for the treatment of diabetic vascular complications. Expert Opinion On Investigational Drugs. 6: 1671-84. PMID 15989571 DOI: 10.1517/13543784.6.11.1671 |
0.422 |
|
| 1997 |
Tilton RG, Kawamura T, Chang KC, Ido Y, Bjercke RJ, Stephan CC, Brock TA, Williamson JR. Vascular dysfunction induced by elevated glucose levels in rats is mediated by vascular endothelial growth factor. The Journal of Clinical Investigation. 99: 2192-202. PMID 9151791 DOI: 10.1172/Jci119392 |
0.37 |
|
| 1997 |
Nyengaard JR, Chang K, Berhorst S, Reiser KM, Williamson JR, Tilton RG. Discordant Effects of Guanidines on Renal Structure and Function and on Regional Vascular Dysfunction and Collagen Changes in Diabetic Rats Diabetes. 46: 94-106. PMID 8971088 DOI: 10.2337/Diab.46.1.94 |
0.41 |
|
| 1996 |
Schmidt RE, Dorsey DA, Beaudet LN, Reiser KM, Williamson JR, Tilton RG. Effect of aminoguanidine on the frequency of neuroaxonal dystrophy in the superior mesenteric sympathetic autonomic ganglia of rats with streptozocin-induced diabetes Diabetes. 45: 284-290. PMID 8593931 DOI: 10.2337/Diab.45.3.284 |
0.381 |
|
| 1995 |
Tilton R, Chang K, Nyengaard JR, Enden MVd, Ido Y, Williamson JR. Inhibition of Sorbitol Dehydrogenase: Effects on Vascular and Neural Dysfunction in Streptozocin-Induced Diabetic Rats Diabetes. 44: 234-242. PMID 7859946 DOI: 10.2337/Diab.44.2.234 |
0.383 |
|
| 1993 |
Williamson JR, Chang K, Frangos M, Hasan KS, Ido Y, Kawamura T, Nyengaard JR, van den Enden M, Kilo C, Tilton RG. Hyperglycemic pseudohypoxia and diabetic complications. Diabetes. 42: 801-13. PMID 8495803 DOI: 10.2337/Diab.42.6.801 |
0.399 |
|
| 1992 |
Corbett JA, Tilton RG, Chang K, Hasan KS, Ido Y, Wang JL, Sweetland MA, Lancaster JR, Williamson JR, McDaniel ML. Aminoguanidine, a novel inhibitor of nitric oxide formation, prevents diabetic vascular dysfunction Diabetes. 41: 552-556. PMID 1376704 DOI: 10.2337/Diab.41.4.552 |
0.409 |
|
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