Year |
Citation |
Score |
2019 |
Prasher D, Zhang H, McCarthy PM, Oudit G, Fedak PW, Greenway SC. Abstract 656: Construction and Application of an Epigenetic Atlas of the Human Heart Circulation Research. 125. DOI: 10.1161/Res.125.Suppl_1.656 |
0.307 |
|
2017 |
Svystonyuk D, Turnbull J, Teng G, Belke D, Guzzardi D, Park D, Kang S, Fedak P. ACELLULAR EXTRACELLULAR MATRIX SCAFFOLD REPROGRAMS CARDIAC FIBROBLASTS AND PROMOTES ADAPTIVE CARDIAC REMODELING AND REPAIR Canadian Journal of Cardiology. 33: S49-S50. DOI: 10.1016/J.Cjca.2017.07.485 |
0.375 |
|
2017 |
Kang S, Verma S, Teng G, Belke D, Svystonyuk D, Guzzardi D, Park D, Turnbull J, Malik G, Fedak P. DIRECT EFFECTS OF EMPAGLIFLOZIN ON EXTRACELLULAR MATRIX REMODELING IN HUMAN CARDIAC FIBROBLASTS: NOVEL TRANSLATIONAL CLUES TO EMPA-REG OUTCOME Canadian Journal of Cardiology. 33: S169. DOI: 10.1016/J.Cjca.2017.07.330 |
0.439 |
|
2017 |
Park D, Regmi S, Svystonyuk D, Belke D, Teng G, Turnbull J, Guzzardi D, Kang S, Schmidt T, Fedak P. IMPLICATIONS OF PRG4/LUBRICIN IN ATTENUATING MYOFIBROBLAST-MEDIATED INTRATHORACIC ADHESION DEVELOPMENT AFTER CARDIAC SURGERY Canadian Journal of Cardiology. 33: S92-S93. DOI: 10.1016/J.Cjca.2017.07.183 |
0.317 |
|
2017 |
Guzzardi D, Teng G, Svystonyuk D, Kang S, Park D, Belke D, Turnbull J, Fedak P. FLUOROQUINOLONE INDUCES HUMAN AORTIC FIBROBLAST-MEDIATED EXTRACELLULAR MATRIX DYSREGULATION Canadian Journal of Cardiology. 33: S38-S39. DOI: 10.1016/J.Cjca.2017.07.092 |
0.311 |
|
2016 |
Svystonyuk D, Mewhort H, Turnbull J, Teng G, Belke D, Guzzardi D, Park D, Kang S, Fedak P. EXTRACELLULAR MATRIX BIOMATERIAL PROMOTES VASCULOGENESIS AND CARDIAC REPAIR: EVIDENCE OF A BIOINDUCTIVE FGF-2 DEPENDENT MECHANISM Canadian Journal of Cardiology. 32: S81-S82. DOI: 10.1016/J.Cjca.2016.07.106 |
0.353 |
|
2015 |
Teng G, Svystonyuk D, Mewhort HE, Turnbull JD, Belke DD, Duff HJ, Fedak PW. Tetrandrine reverses human cardiac myofibroblast activation and myocardial fibrosis. American Journal of Physiology. Heart and Circulatory Physiology. 308: H1564-74. PMID 25862829 DOI: 10.1016/J.Cjca.2014.07.159 |
0.355 |
|
2015 |
Svystonyuk D, Malik G, Mewhort H, Guzzardi D, Park D, Belke D, Teng G, Fedak P. SIS-ECM BIOMATERIAL DECREASES HUMAN CARDIAC MYOFIBROBLAST ACTIVATION AND ATTENUATES LOCAL MATRIX REMODELING Canadian Journal of Cardiology. 31: S194-S195. DOI: 10.1016/J.Cjca.2015.07.412 |
0.347 |
|
2015 |
Mewhort H, Turnbull J, Teng G, Belke D, Svystonyuk D, Guzzardi D, Duff H, Fedak P. SURGICAL APPLICATION OF A NOVEL BIOMATERIAL ENHANCES POST-MI FUNCTIONAL RECOVERY BY STIMULATING VASCULOGENESIS THROUGH AN ACTIVE BIO-INDUCTIVE MECHANISM Canadian Journal of Cardiology. 31: S74. DOI: 10.1016/J.Cjca.2015.07.168 |
0.393 |
|
2014 |
Teo KK, Cohen E, Buller C, Hassan A, Carere R, Cox JL, Ly H, Fedak PW, Chan K, Légaré JF, Connelly K, Tanguay JF, Ye J, Gupta M, John Mancini GB, et al. Canadian Cardiovascular Society/Canadian Association of Interventional Cardiology/Canadian Society of Cardiac Surgery position statement on revascularization--multivessel coronary artery disease. The Canadian Journal of Cardiology. 30: 1482-91. PMID 25475448 DOI: 10.1016/J.Cjca.2014.09.034 |
0.302 |
|
2014 |
Bracey NA, Gershkovich B, Chun J, Vilaysane A, Meijndert HC, Wright JR, Fedak PW, Beck PL, Muruve DA, Duff HJ. Mitochondrial NLRP3 protein induces reactive oxygen species to promote Smad protein signaling and fibrosis independent from the inflammasome. The Journal of Biological Chemistry. 289: 19571-84. PMID 24841199 DOI: 10.1074/Jbc.M114.550624 |
0.331 |
|
2014 |
Mewhort H, Turnbull J, Flewitt J, Meijndert H, Guzzardi D, Lipon B, Svystonyuk D, Fedak P. EXTRACELLULAR MATRIX PATCH THERAPY TO ENHANCE INFARCT HEALING: PRECLINICAL VALIDATION OF A NOVEL SURGICAL STRATEGY Canadian Journal of Cardiology. 30: S252-S253. DOI: 10.1016/J.Cjca.2014.07.437 |
0.308 |
|
2014 |
Mewhort H, Lipon B, Svystonyuk D, Guzzardi D, Fedak P. INFLAMMATION INDUCES POST-ISCHEMIC HEART FAILURE: SYSTEMIC MONOCYTES STIMULATE HUMAN CARDIAC MYOFIBROBLAST ACTIVATION BY DIRECT CELL-CELL CONTACT Canadian Journal of Cardiology. 30: S155. DOI: 10.1016/J.Cjca.2014.07.231 |
0.321 |
|
2014 |
Svystonyuk D, Ngu J, Mewhort H, Guzzardi D, Lipon B, Park D, Teng G, Belke D, Fedak P. FIBROBLAST GROWTH FACTOR (FGF-2) PREVENTS HUMAN CARDIAC FIBROBLAST-MEDIATED EXTRACELLULAR MATRIX REMODELING Canadian Journal of Cardiology. 30: S153. DOI: 10.1016/J.Cjca.2014.07.227 |
0.336 |
|
2013 |
Ngu J, Meijndert C, Mewhort H, Turnbull J, Yong W, Stetler-Stevenson W, Fedak P. The Role of Tissue Inhibitor of Metalloproteinase-2 in Human Cardiac Fibroblast-Mediated Extracellular Matrix Remodeling Canadian Journal of Cardiology. 29: S363-S364. DOI: 10.1016/J.Cjca.2013.07.622 |
0.374 |
|
2013 |
Mewhort H, Turnbull J, Meijndert C, Ngu J, Fedak P. Epicardial Infarct Repair Attenuates Ischemic Remodeling and Heart Failure Canadian Journal of Cardiology. 29: S212-S213. DOI: 10.1016/J.Cjca.2013.07.348 |
0.358 |
|
2012 |
Fedak PW, Bai L, Turnbull J, Ngu J, Narine K, Duff HJ. Cell therapy limits myofibroblast differentiation and structural cardiac remodeling: basic fibroblast growth factor-mediated paracrine mechanism. Circulation. Heart Failure. 5: 349-56. PMID 22508775 DOI: 10.1161/CIRCHEARTFAILURE.111.965889 |
0.305 |
|
2011 |
Deuse T, Adam M, Fedak P, Robbins R, Reichenspurner H, Schrepfer S. 546 Stem Cell Transplantation: HGF or VEGF Enhance Myocardial Function after Infarction The Journal of Heart and Lung Transplantation. 30: S183-S184. DOI: 10.1016/J.Healun.2011.01.557 |
0.37 |
|
2010 |
Deuse T, Fedak P, Robbins R, Reichenspurner H, Schrepfer S. 237: HGF or VEGF Gene Transfer Maximizes Mesenchymal Stem Cell-Based Myocardial Salvage after Acute Myocardial Infarction The Journal of Heart and Lung Transplantation. 29: S81-S81. DOI: 10.1016/J.Healun.2009.11.248 |
0.33 |
|
2009 |
Angoulvant D, Fazel S, Weisel RD, Lai TY, Fedak PW, Chen L, Rafati S, Seneviratne CK, Degousee N, Li RK. Cell-based gene therapy modifies matrix remodeling after a myocardial infarction in tissue inhibitor of matrix metalloproteinase-3-deficient mice. The Journal of Thoracic and Cardiovascular Surgery. 137: 471-80. PMID 19185172 DOI: 10.1016/J.Jtcvs.2008.08.031 |
0.569 |
|
2008 |
Fedak PW. Paracrine effects of cell transplantation: modifying ventricular remodeling in the failing heart. Seminars in Thoracic and Cardiovascular Surgery. 20: 87-93. PMID 18707639 DOI: 10.1053/j.semtcvs.2008.04.001 |
0.327 |
|
2007 |
Tian H, Cimini M, Fedak PW, Altamentova S, Fazel S, Huang ML, Weisel RD, Li RK. TIMP-3 deficiency accelerates cardiac remodeling after myocardial infarction. Journal of Molecular and Cellular Cardiology. 43: 733-43. PMID 17945252 DOI: 10.1016/J.Yjmcc.2007.09.003 |
0.533 |
|
2006 |
Wang CH, Anderson N, Li SH, Szmitko PE, Cherng WJ, Fedak PW, Fazel S, Li RK, Yau TM, Weisel RD, Stanford WL, Verma S. Stem cell factor deficiency is vasculoprotective: unraveling a new therapeutic potential of imatinib mesylate. Circulation Research. 99: 617-25. PMID 16931795 DOI: 10.1161/01.Res.0000243210.79654.Fd |
0.51 |
|
2006 |
Fazel S, Cimini M, Chen L, Li S, Angoulvant D, Fedak P, Verma S, Weisel RD, Keating A, Li RK. Cardioprotective c-kit+ cells are from the bone marrow and regulate the myocardial balance of angiogenic cytokines. The Journal of Clinical Investigation. 116: 1865-77. PMID 16823487 DOI: 10.1172/Jci27019 |
0.576 |
|
2006 |
Fedak PW, Moravec CS, McCarthy PM, Altamentova SM, Wong AP, Skrtic M, Verma S, Weisel RD, Li RK. Altered expression of disintegrin metalloproteinases and their inhibitor in human dilated cardiomyopathy. Circulation. 113: 238-45. PMID 16401770 DOI: 10.1161/CIRCULATIONAHA.105.571414 |
0.518 |
|
2005 |
Fedak PW, Szmitko PE, Weisel RD, Altamentova SM, Nili N, Ohno N, Verma S, Fazel S, Strauss BH, Li RK. Cell transplantation preserves matrix homeostasis: a novel paracrine mechanism. The Journal of Thoracic and Cardiovascular Surgery. 130: 1430-9. PMID 16256799 DOI: 10.1016/J.Jtcvs.2005.05.055 |
0.532 |
|
2005 |
Fazel S, Chen L, Weisel RD, Angoulvant D, Seneviratne C, Fazel A, Cheung P, Lam J, Fedak PW, Yau TM, Li RK. Cell transplantation preserves cardiac function after infarction by infarct stabilization: augmentation by stem cell factor. The Journal of Thoracic and Cardiovascular Surgery. 130: 1310. PMID 16256783 DOI: 10.1016/J.Jtcvs.2005.07.012 |
0.511 |
|
2005 |
Fedak PW, Verma S, Weisel RD, Skrtic M, Li RK. Cardiac remodeling and failure: from molecules to man (Part III). Cardiovascular Pathology : the Official Journal of the Society For Cardiovascular Pathology. 14: 109-19. PMID 15914295 DOI: 10.1016/j.carpath.2005.03.004 |
0.541 |
|
2005 |
Fedak PW, Verma S, Weisel RD, Li RK. Cardiac remodeling and failure From molecules to man (Part II). Cardiovascular Pathology : the Official Journal of the Society For Cardiovascular Pathology. 14: 49-60. PMID 15780796 DOI: 10.1016/j.carpath.2005.01.005 |
0.553 |
|
2005 |
Wang CH, Li SH, Weisel RD, Fedak PW, Hung A, Li RK, Rao V, Hyland K, Cherng WJ, Errett L, Leclerc Y, Bonneau D, Latter DA, Verma S. Tetrahydrobiopterin deficiency exaggerates intimal hyperplasia after vascular injury. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 289: R299-304. PMID 15774769 DOI: 10.1152/ajpregu.00269.2004 |
0.481 |
|
2005 |
Fedak PW, Verma S, Weisel RD, Li RK. Cardiac remodeling and failure: from molecules to man (Part I). Cardiovascular Pathology : the Official Journal of the Society For Cardiovascular Pathology. 14: 1-11. PMID 15710285 DOI: 10.1016/J.Carpath.2004.12.002 |
0.529 |
|
2004 |
Weisel RD, Fazel S, Fedak PW, Li RK. Cardiac restoration by cell transplantation. International Journal of Cardiology. 95: S5-7. PMID 15336835 |
0.516 |
|
2004 |
Liu TB, Fedak PW, Weisel RD, Yasuda T, Kiani G, Mickle DA, Jia ZQ, Li RK. Enhanced IGF-1 expression improves smooth muscle cell engraftment after cell transplantation. American Journal of Physiology. Heart and Circulatory Physiology. 287: H2840-9. PMID 15331370 DOI: 10.1152/ajpheart.00439.2004 |
0.505 |
|
2004 |
Fedak PW, Smookler DS, Kassiri Z, Ohno N, Leco KJ, Verma S, Mickle DA, Watson KL, Hojilla CV, Cruz W, Weisel RD, Li RK, Khokha R. TIMP-3 deficiency leads to dilated cardiomyopathy. Circulation. 110: 2401-9. PMID 15262835 DOI: 10.1161/01.Cir.0000134959.83967.2D |
0.545 |
|
2004 |
Ozawa T, Mickle DA, Weisel RD, Matsubayashi K, Fujii T, Fedak PW, Koyama N, Ikada Y, Li RK. Tissue-engineered grafts matured in the right ventricular outflow tract. Cell Transplantation. 13: 169-77. PMID 15129763 |
0.473 |
|
2004 |
Verma S, Rao V, Weisel RD, Li SH, Fedak PW, Miriuka S, Li RK. Novel cardioprotective effects of pravastatin in human ventricular cardiomyocytes subjected to hypoxia and reoxygenation: beneficial effects of statins independent of endothelial cells. The Journal of Surgical Research. 119: 66-71. PMID 15126084 DOI: 10.1016/J.Jss.2003.10.011 |
0.565 |
|
2004 |
Wang CH, Ciliberti N, Li SH, Szmitko PE, Weisel RD, Fedak PW, Al-Omran M, Cherng WJ, Li RK, Stanford WL, Verma S. Rosiglitazone facilitates angiogenic progenitor cell differentiation toward endothelial lineage: a new paradigm in glitazone pleiotropy. Circulation. 109: 1392-400. PMID 14993120 DOI: 10.1161/01.Cir.0000123231.49594.21 |
0.495 |
|
2004 |
Li SH, Szmitko PE, Weisel RD, Wang CH, Fedak PW, Li RK, Mickle DA, Verma S. C-reactive protein upregulates complement-inhibitory factors in endothelial cells. Circulation. 109: 833-6. PMID 14967730 DOI: 10.1161/01.CIR.0000117087.27524.0E |
0.504 |
|
2003 |
Mikhail P, Verma S, Fedak PW, Weisel RD, Li RK. Does ischemic preconditioning afford clinically relevant cardioprotection? American Journal of Cardiovascular Drugs : Drugs, Devices, and Other Interventions. 3: 1-11. PMID 14727941 |
0.482 |
|
2003 |
Verma S, Badiwala MV, Weisel RD, Li SH, Wang CH, Fedak PW, Li RK, Mickle DA. C-reactive protein activates the nuclear factor-kappaB signal transduction pathway in saphenous vein endothelial cells: implications for atherosclerosis and restenosis. The Journal of Thoracic and Cardiovascular Surgery. 126: 1886-91. PMID 14688701 DOI: 10.1016/J.Jtcvs.2003.07.026 |
0.489 |
|
2003 |
Ohno N, Fedak PW, Weisel RD, Mickle DA, Fujii T, Li RK. Transplantation of cryopreserved muscle cells in dilated cardiomyopathy: effects on left ventricular geometry and function. The Journal of Thoracic and Cardiovascular Surgery. 126: 1537-48. PMID 14666030 DOI: 10.1016/S0022-5223(03)01021-3 |
0.521 |
|
2003 |
Fedak PW, Weisel RD, Verma S, Mickle DA, Li RK. Restoration and regeneration of failing myocardium with cell transplantation and tissue engineering. Seminars in Thoracic and Cardiovascular Surgery. 15: 277-86. PMID 12973705 DOI: 10.1016/S1043-0679(03)70007-0 |
0.568 |
|
2003 |
Matsubayashi K, Fedak PW, Mickle DA, Weisel RD, Ozawa T, Li RK. Improved left ventricular aneurysm repair with bioengineered vascular smooth muscle grafts. Circulation. 108: II219-25. PMID 12970236 DOI: 10.1161/01.cir.0000087450.34497.9a |
0.489 |
|
2003 |
Verma S, Li SH, Wang CH, Fedak PW, Li RK, Weisel RD, Mickle DA. Resistin promotes endothelial cell activation: further evidence of adipokine-endothelial interaction. Circulation. 108: 736-40. PMID 12874180 DOI: 10.1161/01.Cir.0000084503.91330.49 |
0.466 |
|
2003 |
Dhillon B, Badiwala MV, Li SH, Li RK, Weisel RD, Mickle DA, Fedak PW, Rao V, Verma S. Caveolin: a key target for modulating nitric oxide availability in health and disease. Molecular and Cellular Biochemistry. 247: 101-9. PMID 12841637 DOI: 10.1023/A:1024198518582 |
0.471 |
|
2003 |
Tang GH, Fedak PW, Yau TM, Weisel RD, Kulik A, Mickle DA, Li RK. Cell transplantation to improve ventricular function in the failing heart. European Journal of Cardio-Thoracic Surgery : Official Journal of the European Association For Cardio-Thoracic Surgery. 23: 907-16. PMID 12829066 DOI: 10.1016/S1010-7940(03)00140-4 |
0.529 |
|
2003 |
Verma S, Wang CH, Weisel RD, Badiwala MV, Li SH, Fedak PW, Li RK, Mickle DA. Hyperglycemia potentiates the proatherogenic effects of C-reactive protein: reversal with rosiglitazone. Journal of Molecular and Cellular Cardiology. 35: 417-9. PMID 12689821 DOI: 10.1016/S0022-2828(03)00042-7 |
0.512 |
|
2003 |
Wang CH, Li SH, Weisel RD, Fedak PW, Dumont AS, Szmitko P, Li RK, Mickle DA, Verma S. C-reactive protein upregulates angiotensin type 1 receptors in vascular smooth muscle. Circulation. 107: 1783-90. PMID 12665485 DOI: 10.1161/01.Cir.0000061916.95736.E5 |
0.491 |
|
2003 |
Fedak PW, Altamentova SM, Weisel RD, Nili N, Ohno N, Verma S, Lee TY, Kiani C, Mickle DA, Strauss BH, Li RK. Matrix remodeling in experimental and human heart failure: a possible regulatory role for TIMP-3. American Journal of Physiology. Heart and Circulatory Physiology. 284: H626-34. PMID 12388270 DOI: 10.1152/Ajpheart.00684.2002 |
0.515 |
|
2003 |
Verma S, Badiwala MV, Wang CH, Weisel RD, Li S, Bikramjit D, Fedak PW, Li R, Mickle DA. C-reactive protein activates the NF-κB signal transduction pathway in human saphenous vein endothelial cells Journal of the American College of Cardiology. 41: 318. DOI: 10.1016/S0735-1097(03)82487-7 |
0.313 |
|
2002 |
Ohno N, Fedak PW, Weisel RD, Komeda M, Mickle DA, Li RK. Cell transplantation in non-ischemic dilated cardiomyopathy. A novel biological approach for ventricular restoration. The Japanese Journal of Thoracic and Cardiovascular Surgery : Official Publication of the Japanese Association For Thoracic Surgery = Nihon KyōBu Geka Gakkai Zasshi. 50: 457-60. PMID 12478864 DOI: 10.1007/Bf02919635 |
0.488 |
|
2002 |
Akhyari P, Fedak PW, Weisel RD, Lee TY, Verma S, Mickle DA, Li RK. Mechanical stretch regimen enhances the formation of bioengineered autologous cardiac muscle grafts. Circulation. 106: I137-42. PMID 12354723 DOI: 10.1161/01.Cir.0000032893.55215.Fc |
0.513 |
|
2002 |
Verma S, Wang CH, Li SH, Dumont AS, Fedak PW, Badiwala MV, Dhillon B, Weisel RD, Li RK, Mickle DA, Stewart DJ. A self-fulfilling prophecy: C-reactive protein attenuates nitric oxide production and inhibits angiogenesis. Circulation. 106: 913-9. PMID 12186793 DOI: 10.1161/01.Cir.0000029802.88087.5E |
0.447 |
|
2002 |
Verma S, Maitland A, Weisel RD, Li SH, Fedak PW, Pomroy NC, Mickle DA, Li RK, Ko L, Rao V. Hyperglycemia exaggerates ischemia-reperfusion-induced cardiomyocyte injury: reversal with endothelin antagonism. The Journal of Thoracic and Cardiovascular Surgery. 123: 1120-4. PMID 12063458 DOI: 10.1067/Mtc.2002.121973 |
0.468 |
|
2002 |
Verma S, Maitland A, Weisel RD, Fedak PW, Li SH, Mickle DA, Li RK, Ko L, Rao V. Increased endothelin-1 production in diabetic patients after cardioplegic arrest and reperfusion impairs coronary vascular reactivity: reversal by means of endothelin antagonism. The Journal of Thoracic and Cardiovascular Surgery. 123: 1114-9. PMID 12063457 DOI: 10.1067/Mtc.2002.121972 |
0.467 |
|
2002 |
Verma S, Maitland A, Weisel RD, Fedak PW, Pomroy NC, Li SH, Mickle DA, Li RK, Rao V. Novel cardioprotective effects of tetrahydrobiopterin after anoxia and reoxygenation: Identifying cellular targets for pharmacologic manipulation. The Journal of Thoracic and Cardiovascular Surgery. 123: 1074-83. PMID 12063453 DOI: 10.1067/Mtc.2002.121687 |
0.538 |
|
2002 |
Verma S, Fedak PW, Weisel RD, Butany J, Rao V, Maitland A, Li RK, Dhillon B, Yau TM. Fundamentals of reperfusion injury for the clinical cardiologist. Circulation. 105: 2332-6. PMID 12021216 DOI: 10.1161/01.Cir.0000016602.96363.36 |
0.486 |
|
2002 |
Verma S, Li SH, Badiwala MV, Weisel RD, Fedak PW, Li RK, Dhillon B, Mickle DA. Endothelin antagonism and interleukin-6 inhibition attenuate the proatherogenic effects of C-reactive protein. Circulation. 105: 1890-6. PMID 11997273 DOI: 10.1161/01.Cir.0000015126.83143.B4 |
0.446 |
|
2002 |
Shiono N, Rao V, Weisel RD, Kawasaki M, Li RK, Mickle DA, Fedak PW, Tumiati LC, Ko L, Verma S. L-arginine protects human heart cells from low-volume anoxia and reoxygenation. American Journal of Physiology. Heart and Circulatory Physiology. 282: H805-15. PMID 11834473 DOI: 10.1152/ajpheart.00594.2001 |
0.494 |
|
2002 |
Miriuka S, Rao V, Weisel R, Li S, Anderson T, Maitland A, Fedak P, Li R, Verma S. Cyclosporin induced endothelial dysfunction: effects of the nitric oxide cofactor, tetrahydrobiopterin The Journal of Heart and Lung Transplantation. 21: 130-131. DOI: 10.1016/S1053-2498(01)00644-1 |
0.461 |
|
2002 |
Verma S, Shiono N, Li R, Mickle DA, Fedak PW, Weisel RD. L-arginine protects human heart cells from simulated anoxia and reoxgenation Journal of the American College of Cardiology. 39: 451-452. DOI: 10.1016/S0735-1097(02)82029-0 |
0.324 |
|
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