Joshua C. Harrell, Ph.D. - Publications

Affiliations: 
2007 University of Colorado Anschutz Medical Campus, Denver, Aurora, CO 
Area:
Molecular Biology, Oncology

43 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Patel NH, Sohal SS, Manjili MH, Harrell JC, Gewirtz DA. The Roles of Autophagy and Senescence in the Tumor Cell Response to Radiation. Radiation Research. 194: 103-115. PMID 32845995 DOI: 10.1667/Rade-20-00009  0.357
2020 Finlay-Schultz J, Jacobsen BM, Riley D, Paul KV, Turner S, Ferreira-Gonzalez A, Harrell JC, Kabos P, Sartorius CA. New generation breast cancer cell lines developed from patient-derived xenografts. Breast Cancer Research : Bcr. 22: 68. PMID 32576280 DOI: 10.1186/s13058-020-01300-y  0.585
2020 Alzubi MA, Boyd DC, Harrell JC. The utility of the "Glowing Head" mouse for breast cancer metastasis research. Clinical & Experimental Metastasis. PMID 31938954 DOI: 10.1007/s10585-020-10020-8  0.47
2020 Cai Q, Harrell JC, Koblinski J, Oh Y. OR05-02 The IGFBP-3/IGFBP-3 Receptor Axis Is a New Therapeutic Target for Triple Negative Breast Cancer Journal of the Endocrine Society. 4. DOI: 10.1210/jendso/bvaa046.1885  0.424
2020 Woock AE, Grible JM, Zot P, Harrell JC, Michael I, Clevenger CV. SAT-139 STAT5A Regulation by Serine Phosphorylation in Breast Cancer Journal of the Endocrine Society. 4. DOI: 10.1210/Jendso/Bvaa046.1035  0.506
2020 Grible JM, Zot P, Harrell JC, Idowu M, Clevenger CV. SAT-130 The Intermediate Prolactin Receptor Is a Breast Cancer Oncogene Journal of the Endocrine Society. 4. DOI: 10.1210/Jendso/Bvaa046.1033  0.554
2019 Alzubi MA, Sohal SS, Sriram M, Turner TH, Zot P, Idowu M, Harrell JC. Quantitative assessment of breast cancer liver metastasis expansion with patient-derived xenografts. Clinical & Experimental Metastasis. PMID 31069566 DOI: 10.1007/s10585-019-09968-z  0.467
2019 Alzubi MA, Turner TH, Olex AL, Sohal SS, Tobin NP, Recio SG, Bergh J, Hatschek T, Parker JS, Sartorius CA, Perou CM, Dozmorov MG, Harrell JC. Separation of breast cancer and organ microenvironment transcriptomes in metastases. Breast Cancer Research : Bcr. 21: 36. PMID 30841919 DOI: 10.1186/S13058-019-1123-2  0.374
2019 Murray GF, Turner TH, Guest D, Leslie KA, Alzubi MA, Radhakrishnan SK, Harrell JC, Reed J. QPI Allows in vitro Drug Screening of Triple Negative Breast Cancer PDX Tumors and Fine Needle Biopsies Frontiers in Physics. 7. DOI: 10.3389/fphy.2019.00158  0.477
2018 Murray GF, Turner TH, Leslie KA, Alzubi MA, Guest D, Sohal SS, Teitell MA, Harrell JC, Reed J. Live Cell Mass Accumulation Measurement Non-Invasively Predicts Carboplatin Sensitivity in Triple-Negative Breast Cancer Patient-Derived Xenografts. Acs Omega. 3: 17687-17692. PMID 30613814 DOI: 10.1021/acsomega.8b02224  0.54
2018 Maczis MA, Maceyka M, Waters MR, Newton J, Singh M, Rigsby MF, Turner TH, Alzubi MA, Harrell JC, Milstien S, Spiegel S. Sphingosine kinase 1 activation by estrogen receptor α36 contributes to tamoxifen resistance in breast cancer. Journal of Lipid Research. PMID 30315000 DOI: 10.1194/jlr.M085191  0.52
2018 Knott SRV, Wagenblast E, Khan S, Kim SY, Soto M, Wagner M, Turgeon MO, Fish L, Erard N, Gable AL, Maceli AR, Dickopf S, Papachristou EK, D'Santos CS, Carey LA, ... ... Harrell JC, et al. Erratum: Asparagine bioavailability governs metastasis in a model of breast cancer. Nature. 556: 135. PMID 29620732 DOI: 10.1038/nature26162  0.437
2018 Turner TH, Alzubi MA, Sohal SS, Olex AL, Dozmorov MG, Harrell JC. Characterizing the efficacy of cancer therapeutics in patient-derived xenograft models of metastatic breast cancer. Breast Cancer Research and Treatment. PMID 29532339 DOI: 10.1007/s10549-018-4748-4  0.51
2018 Knott SRV, Wagenblast E, Khan S, Kim SY, Soto M, Wagner M, Turgeon MO, Fish L, Erard N, Gable AL, Maceli AR, Dickopf S, Papachristou EK, D'Santos CS, Carey LA, ... ... Harrell JC, et al. Asparagine bioavailability governs metastasis in a model of breast cancer. Nature. PMID 29414946 DOI: 10.1038/Nature25465  0.474
2017 Harrell JC, Shroka TM, Jacobsen BM. Estrogen induces c-Kit and an aggressive phenotype in a model of invasive lobular breast cancer. Oncogenesis. 6: 396. PMID 29176653 DOI: 10.1038/s41389-017-0002-x  0.681
2017 Tobin NP, Lundberg A, Lindström LS, Harrell JC, Foukakis T, Carlsson L, Einbeigi Z, Linderholm BK, Loman N, Malmberg M, Fernö M, Czene K, Perou CM, Bergh J, Hatschek T. PAM50 provides prognostic information when applied to the lymph node metastases of advanced breast cancer patients. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 28972041 DOI: 10.1158/1078-0432.Ccr-17-2301  0.46
2016 Medler TR, Craig JM, Fiorillo AA, Feeney YB, Harrell JC, Clevenger CV. HDAC6 Deacetylates HMGN2 to Regulate Stat5a Activity and Breast Cancer Growth. Molecular Cancer Research : McR. PMID 27358110 DOI: 10.1158/1541-7786.MCR-16-0109  0.549
2016 Wahdan-Alaswad R, Harrell JC, Fan Z, Edgerton SM, Liu B, Thor AD. Metformin Attenuates Transforming Growth Factor Beta (TGF-β) Mediated Oncogenesis in Mesenchymal Stem-like/Claudin-low Triple Negative Breast Cancer. Cell Cycle (Georgetown, Tex.). 0. PMID 26919310 DOI: 10.1080/15384101.2016.1152432  0.355
2015 Voduc KD, Nielsen TO, Perou CM, Harrell JC, Fan C, Kennecke H, Minn AJ, Cryns VL, Cheang MC. αB-crystallin Expression in Breast Cancer is Associated with Brain Metastasis. Npj Breast Cancer. 1. PMID 27656679 DOI: 10.1038/npjbcancer.2015.14  0.5
2015 Black JL, Harrell JC, Leisner TM, Fellmeth MJ, George SD, Reinhold D, Baker NM, Jones CD, Der CJ, Perou CM, Parise LV. CIB1 depletion impairs cell survival and tumor growth in triple-negative breast cancer. Breast Cancer Research and Treatment. PMID 26105795 DOI: 10.1007/S10549-015-3458-4  0.56
2015 Ince TA, Sousa AD, Jones MA, Harrell JC, Agoston ES, Krohn M, Selfors LM, Liu W, Chen K, Yong M, Buchwald P, Wang B, Hale KS, Cohick E, Sergent P, et al. Characterization of twenty-five ovarian tumour cell lines that phenocopy primary tumours. Nature Communications. 6: 7419. PMID 26080861 DOI: 10.1038/Ncomms8419  0.327
2014 Wang CA, Harrell JC, Iwanaga R, Jedlicka P, Ford HL. Vascular endothelial growth factor C promotes breast cancer progression via a novel antioxidant mechanism that involves regulation of superoxide dismutase 3. Breast Cancer Research : Bcr. 16: 462. PMID 25358638 DOI: 10.1186/S13058-014-0462-2  0.453
2014 Bockhorn J, Prat A, Chang YF, Liu X, Huang S, Shang M, Nwachukwu C, Gomez-Vega MJ, Harrell JC, Olopade OI, Perou CM, Liu H. Differentiation and loss of malignant character of spontaneous pulmonary metastases in patient-derived breast cancer models. Cancer Research. 74: 7406-17. PMID 25339353 DOI: 10.1158/0008-5472.Can-14-1188  0.516
2014 Drews-Elger K, Brinkman JA, Miller P, Shah SH, Harrell JC, da Silva TG, Ao Z, Schlater A, Azzam DJ, Diehl K, Thomas D, Slingerland JM, Perou CM, Lippman ME, El-Ashry D. Primary breast tumor-derived cellular models: characterization of tumorigenic, metastatic, and cancer-associated fibroblasts in dissociated tumor (DT) cultures. Breast Cancer Research and Treatment. 144: 503-17. PMID 24567196 DOI: 10.1007/S10549-014-2887-9  0.596
2014 Santagata S, Thakkar A, Ergonul A, Wang B, Woo T, Hu R, Harrell JC, McNamara G, Schwede M, Culhane AC, Kindelberger D, Rodig S, Richardson A, Schnitt SJ, Tamimi RM, et al. Taxonomy of breast cancer based on normal cell phenotype predicts outcome. The Journal of Clinical Investigation. 124: 859-70. PMID 24463450 DOI: 10.1172/Jci70941  0.64
2014 Xiao L, Harrell JC, Perou CM, Dudley AC. Identification of a stable molecular signature in mammary tumor endothelial cells that persists in vitro. Angiogenesis. 17: 511-8. PMID 24257808 DOI: 10.1007/S10456-013-9409-Y  0.382
2014 Harrell JC, Pfefferle AD, Zalles N, Prat A, Fan C, Khramtsov A, Olopade OI, Troester MA, Dudley AC, Perou CM. Endothelial-like properties of claudin-low breast cancer cells promote tumor vascular permeability and metastasis. Clinical & Experimental Metastasis. 31: 33-45. PMID 23975155 DOI: 10.1007/S10585-013-9607-4  0.601
2013 Pfefferle AD, Herschkowitz JI, Usary J, Harrell JC, Spike BT, Adams JR, Torres-Arzayus MI, Brown M, Egan SE, Wahl GM, Rosen JM, Perou CM. Transcriptomic classification of genetically engineered mouse models of breast cancer identifies human subtype counterparts. Genome Biology. 14: R125. PMID 24220145 DOI: 10.1186/Gb-2013-14-11-R125  0.482
2013 Jambal P, Badtke MM, Harrell JC, Borges VF, Post MD, Sollender GE, Spillman MA, Horwitz KB, Jacobsen BM. Estrogen switches pure mucinous breast cancer to invasive lobular carcinoma with mucinous features. Breast Cancer Research and Treatment. 137: 431-48. PMID 23247610 DOI: 10.1007/S10549-012-2377-X  0.637
2012 Kabos P, Finlay-Schultz J, Li C, Kline E, Finlayson C, Wisell J, Manuel CA, Edgerton SM, Harrell JC, Elias A, Sartorius CA. Patient-derived luminal breast cancer xenografts retain hormone receptor heterogeneity and help define unique estrogen-dependent gene signatures. Breast Cancer Research and Treatment. 135: 415-32. PMID 22821401 DOI: 10.1007/s10549-012-2164-8  0.668
2012 Iwanaga R, Wang CA, Micalizzi DS, Harrell JC, Jedlicka P, Sartorius CA, Kabos P, Farabaugh SM, Bradford AP, Ford HL. Expression of Six1 in luminal breast cancers predicts poor prognosis and promotes increases in tumor initiating cells by activation of extracellular signal-regulated kinase and transforming growth factor-beta signaling pathways. Breast Cancer Research : Bcr. 14: R100. PMID 22765220 DOI: 10.1186/Bcr3219  0.621
2012 Haughian JM, Pinto MP, Harrell JC, Bliesner BS, Joensuu KM, Dye WW, Sartorius CA, Tan AC, Heikkilä P, Perou CM, Horwitz KB. Maintenance of hormone responsiveness in luminal breast cancers by suppression of Notch. Proceedings of the National Academy of Sciences of the United States of America. 109: 2742-7. PMID 21969591 DOI: 10.1073/Pnas.1106509108  0.751
2011 Camp JT, Elloumi F, Roman-Perez E, Rein J, Stewart DA, Harrell JC, Perou CM, Troester MA. Interactions with fibroblasts are distinct in Basal-like and luminal breast cancers. Molecular Cancer Research : McR. 9: 3-13. PMID 21131600 DOI: 10.1158/1541-7786.Mcr-10-0372  0.599
2010 Spillman MA, Manning NG, Dye WW, Sartorius CA, Post MD, Harrell JC, Jacobsen BM, Horwitz KB. Tissue-specific pathways for estrogen regulation of ovarian cancer growth and metastasis. Cancer Research. 70: 8927-36. PMID 20959477 DOI: 10.1158/0008-5472.Can-10-1238  0.751
2010 Pinto MP, Badtke MM, Dudevoir ML, Harrell JC, Jacobsen BM, Horwitz KB. Vascular endothelial growth factor secreted by activated stroma enhances angiogenesis and hormone-independent growth of estrogen receptor-positive breast cancer. Cancer Research. 70: 2655-64. PMID 20332242 DOI: 10.1158/0008-5472.Can-09-4373  0.633
2009 Micalizzi DS, Christensen KL, Jedlicka P, Coletta RD, Barón AE, Harrell JC, Horwitz KB, Billheimer D, Heichman KA, Welm AL, Schiemann WP, Ford HL. The Six1 homeoprotein induces human mammary carcinoma cells to undergo epithelial-mesenchymal transition and metastasis in mice through increasing TGF-beta signaling. The Journal of Clinical Investigation. 119: 2678-90. PMID 19726885 DOI: 10.1172/Jci37815  0.674
2008 Horwitz KB, Dye WW, Harrell JC, Kabos P, Sartorius CA. Rare steroid receptor-negative basal-like tumorigenic cells in luminal subtype human breast cancer xenografts. Proceedings of the National Academy of Sciences of the United States of America. 105: 5774-9. PMID 18391223 DOI: 10.1073/Pnas.0706216105  0.782
2008 Harrell JC, Dye WW, Harvell DM, Sartorius CA, Horwitz KB. Contaminating cells alter gene signatures in whole organ versus laser capture microdissected tumors: a comparison of experimental breast cancers and their lymph node metastases. Clinical & Experimental Metastasis. 25: 81-8. PMID 17932773 DOI: 10.1007/S10585-007-9105-7  0.699
2007 Harrell JC, Dye WW, Harvell DM, Pinto M, Jedlicka P, Sartorius CA, Horwitz KB. Estrogen insensitivity in a model of estrogen receptor positive breast cancer lymph node metastasis. Cancer Research. 67: 10582-91. PMID 17975003 DOI: 10.1158/0008-5472.Can-07-1655  0.784
2006 Harrell JC, Dye WW, Allred DC, Jedlicka P, Spoelstra NS, Sartorius CA, Horwitz KB. Estrogen receptor positive breast cancer metastasis: altered hormonal sensitivity and tumor aggressiveness in lymphatic vessels and lymph nodes. Cancer Research. 66: 9308-15. PMID 16982776 DOI: 10.1158/0008-5472.Can-06-1769  0.771
2006 Jacobsen BM, Harrell JC, Jedlicka P, Borges VF, Varella-Garcia M, Horwitz KB. Spontaneous fusion with, and transformation of mouse stroma by, malignant human breast cancer epithelium. Cancer Research. 66: 8274-9. PMID 16912208 DOI: 10.1158/0008-5472.Can-06-1456  0.739
2005 Massart F, Harrell JC, Federico G, Saggese G. Human breast milk and xenoestrogen exposure: a possible impact on human health. Journal of Perinatology : Official Journal of the California Perinatal Association. 25: 282-8. PMID 15605068 DOI: 10.1038/Sj.Jp.7211251  0.381
2003 Korach KS, Emmen JM, Walker VR, Hewitt SC, Yates M, Hall JM, Swope DL, Harrell JC, Couse JF. Update on animal models developed for analyses of estrogen receptor biological activity. The Journal of Steroid Biochemistry and Molecular Biology. 86: 387-91. PMID 14623535  0.304
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