| Year |
Citation |
Score |
| 2023 |
Paudel S, Mishra N, Agarwal R. Phytochemicals as Immunomodulatory Molecules in Cancer Therapeutics. Pharmaceuticals (Basel, Switzerland). 16. PMID 38139779 DOI: 10.3390/ph16121652 |
0.319 |
|
| 2023 |
Kandhari K, Mishra JPN, Agarwal R, Singh RP. Acacetin induces sustained ERK1/2 activation and RIP1-dependent necroptotic death in breast cancer cells. Toxicology and Applied Pharmacology. 462: 116409. PMID 36740148 DOI: 10.1016/j.taap.2023.116409 |
0.302 |
|
| 2022 |
Kandhari K, Paudel S, Raina K, Agarwal C, Kant R, Wempe MF, O'Bryant C, Agarwal R. Comparative Pre-clinical Efficacy of Chinese and Indian Cultivars of Bitter Melon () against Pancreatic Cancer. Journal of Cancer Prevention. 26: 266-276. PMID 35047453 DOI: 10.15430/JCP.2021.26.4.266 |
0.329 |
|
| 2021 |
Romanucci V, Giordano M, Pagano R, Agarwal C, Agarwal R, Zarrelli A, Di Fabio G. Solid-phase synthesis of curcumin mimics and their anticancer activity against human pancreatic, prostate, and colorectal cancer cell lines. Bioorganic & Medicinal Chemistry. 42: 116249. PMID 34126286 DOI: 10.1016/j.bmc.2021.116249 |
0.337 |
|
| 2020 |
Guth A, Monk E, Agarwal R, Bergman BC, Zemski-Berry KA, Minic A, Jordan K, Schlaepfer IR. Targeting Fat Oxidation in Mouse Prostate Cancer Decreases Tumor Growth and Stimulates Anti-Cancer Immunity. International Journal of Molecular Sciences. 21. PMID 33352903 DOI: 10.3390/ijms21249660 |
0.304 |
|
| 2020 |
Dhar D, Raina K, Kumar D, Wempe MF, Bagby SM, Pitts TM, Orlicky DJ, Agarwal C, Messersmith WA, Agarwal R. Bitter melon juice intake with gemcitabine intervention circumvents resistance to gemcitabine in pancreatic patient-derived xenograft tumors. Molecular Carcinogenesis. PMID 32816368 DOI: 10.1002/Mc.23251 |
0.382 |
|
| 2020 |
Prasad RR, Paudel S, Raina K, Agarwal R. Silibinin and non-melanoma skin cancers. Journal of Traditional and Complementary Medicine. 10: 236-244. PMID 32670818 DOI: 10.1016/J.Jtcme.2020.02.003 |
0.452 |
|
| 2020 |
Anwar A, Anwar H, Yamauchi T, Tseng R, Agarwal R, Horwitz LD, Zhai Z, Fujita M. Bucillamine Inhibits UVB-induced MAPK Activation and Apoptosis in Human HaCaT Keratinocytes and SKH-1 Hairless Mouse Skin. Photochemistry and Photobiology. PMID 32077107 DOI: 10.1111/Php.13228 |
0.445 |
|
| 2020 |
Deep G, Jain A, Kumar A, Agarwal C, Kim S, Leevy WM, Agarwal R. Exosomes secreted by prostate cancer cells under hypoxia promote matrix metalloproteinases activity at pre-metastatic niches. Molecular Carcinogenesis. PMID 31943365 DOI: 10.1002/Mc.23157 |
0.388 |
|
| 2020 |
Maroni P, Kessler ER, Rodrigues-Pessoa R, Nicklawsky A, Flaig T, Lam E, Bernard B, Moore J, Anderson K, Gao D, Raina K, Agarwal R. Abstract CT207: A phase II trial using grape seed extract for prostate cancer patients with non-metastatic PSA progression after local therapy Cancer Research. 80. DOI: 10.1158/1538-7445.Am2020-Ct207 |
0.317 |
|
| 2019 |
Goswami DG, Kant R, Ammar DA, Agarwal C, Gomez J, Agarwal R, Saba LM, Fritz KS, Tewari-Singh N. Toxic consequences and oxidative protein carbonylation from chloropicrin exposure in human corneal epithelial cells. Toxicology Letters. PMID 31884112 DOI: 10.1016/J.Toxlet.2019.12.023 |
0.434 |
|
| 2019 |
da Silva RF, Banzato TP, Alves LF, Carvalho JE, Agarwal R, Cagnon VHA. Antiangiogenic therapy with Nintedanib affects hypoxia, angiogenesis and apoptosis in the ventral prostate of TRAMP animals. Cell and Tissue Research. PMID 31473819 DOI: 10.1007/S00441-019-03091-X |
0.42 |
|
| 2019 |
Goswami DG, Kant R, Ammar DA, Kumar D, Enzenauer RW, Petrash JM, Tewari-Singh N, Agarwal R. Acute corneal injury in rabbits following nitrogen mustard ocular exposure. Experimental and Molecular Pathology. 104275. PMID 31233733 DOI: 10.1016/J.Yexmp.2019.104275 |
0.329 |
|
| 2019 |
Dhar D, Raina K, Kant R, Wempe MF, Serkova NJ, Agarwal C, Agarwal R. Bitter melon juice-intake modulates glucose metabolism and lactate efflux in tumors in its efficacy against pancreatic cancer. Carcinogenesis. PMID 31194859 DOI: 10.1093/Carcin/Bgz114 |
0.331 |
|
| 2019 |
Rigby C, Deep G, Jain A, Orlicky DJ, Agarwal C, Agarwal R. Silibinin inhibits ultraviolet B radiation-induced mast cells recruitment and bone morphogenetic protein 2 expression in the skin at early stages in Ptch(+/-) mouse model of basal cell carcinoma. Molecular Carcinogenesis. PMID 30912211 DOI: 10.1002/Mc.23008 |
0.443 |
|
| 2019 |
Tyagi A, Kumar S, Raina K, Wempe MF, Maroni PD, Agarwal R, Agarwal C. Differential effect of grape seed extract and its active constituent procyanidin B2 3,3″-di-O-gallate against prostate cancer stem cells. Molecular Carcinogenesis. PMID 30828884 DOI: 10.1002/Mc.22995 |
0.417 |
|
| 2019 |
Rigby CM, Deep G, Jain AK, Orlicky DJ, Agarwal C, Raina K, Agarwal R. Abstract 5088: Silibinin inhibits UVB-induced promotion and progression of microscopic basal cell carcinoma formation via targeting bone morphogenic protein 2 Cancer Research. 79: 5088-5088. DOI: 10.1158/1538-7445.Am2019-5088 |
0.475 |
|
| 2019 |
Dhar D, Kant R, Raina K, Wempe MF, Serkova NJ, Agarwal C, Agarwal R. Abstract 5078: Modulation of glucose metabolism and lactate efflux in tumors by bitter melon juice in its efficacy against pancreatic cancer Cancer Research. 79: 5078-5078. DOI: 10.1158/1538-7445.Am2019-5078 |
0.381 |
|
| 2019 |
Dhar D, Kumar D, Raina K, Orlicky DJ, Agarwal C, Agarwal R. Abstract 2123: A combinatorial approach using gemcitabine and bitter melon juice overcomes drug resistance impacting gemcitabine uptake and metabolism Cancer Research. 79: 2123-2123. DOI: 10.1158/1538-7445.Am2019-2123 |
0.308 |
|
| 2018 |
Dheeraj A, Agarwal C, Schlaepfer IR, Raben D, Singh R, Agarwal R, Deep G. A novel approach to target hypoxic cancer cells via combining β-oxidation inhibitor etomoxir with radiation. Hypoxia (Auckland, N.Z.). 6: 23-33. PMID 30175155 DOI: 10.2147/Hp.S163115 |
0.396 |
|
| 2018 |
da Silva RF, Dhar D, Raina K, Kumar D, Kant R, Cagnon VHA, Agarwal C, Agarwal R. Nintedanib inhibits growth of human prostate carcinoma cells by modulating both cell cycle and angiogenesis regulators. Scientific Reports. 8: 9540. PMID 29934570 DOI: 10.1038/S41598-018-27831-1 |
0.474 |
|
| 2018 |
Dhar D, Deep G, Kumar S, Wempe MF, Raina K, Agarwal C, Agarwal R. Bitter melon juice exerts its efficacy against pancreatic cancer via targeting both bulk and cancer stem cells. Molecular Carcinogenesis. PMID 29727019 DOI: 10.1002/Mc.22833 |
0.414 |
|
| 2018 |
Jones DZ, Schmidt ML, Suman S, Hobbing KR, Barve SS, Gobejishvili L, Brock G, Klinge CM, Rai SN, Park J, Clark GJ, Agarwal R, Kidd LR. Micro-RNA-186-5p inhibition attenuates proliferation, anchorage independent growth and invasion in metastatic prostate cancer cells. Bmc Cancer. 18: 421. PMID 29653561 DOI: 10.1186/S12885-018-4258-0 |
0.391 |
|
| 2018 |
Panda PK, Naik PP, Praharaj PP, Meher BR, Gupta PK, Verma RS, Maiti TK, Shanmugam MK, Chinnathambi A, Alharbi SA, Sethi G, Agarwal R, Bhutia SK. Abrus agglutinin stimulates BMP-2-dependent differentiation through autophagic degradation of β-catenin in colon cancer stem cells. Molecular Carcinogenesis. PMID 29457276 DOI: 10.1002/Mc.22791 |
0.411 |
|
| 2018 |
Romanucci V, Agarwal C, Agarwal R, Pannecouque C, Iuliano M, De Tommaso G, Caruso T, Di Fabio G, Zarrelli A. Silibinin phosphodiester glyco-conjugates: Synthesis, redox behaviour and biological investigations. Bioorganic Chemistry. 77: 349-359. PMID 29421711 DOI: 10.1016/J.Bioorg.2018.01.026 |
0.35 |
|
| 2018 |
Agarwal R, Agarwal C. Abstract B32: Translational potential of a small-molecule silibinin in colorectal cancer: Targeting cancer stem cells and their inflammatory niche Clinical Cancer Research. 24. DOI: 10.1158/1557-3265.Tcm17-B32 |
0.433 |
|
| 2018 |
Guth AM, Salzmann-Sullivan M, Beaton C, Goldkorn A, Gibson EA, Kessler E, Lam E, Flaig T, Agarwal R, Schlaepfer IR. Abstract A021: CPT1A-mediated fat oxidation and its role in the immune response to prostate cancer Cancer Research. 78. DOI: 10.1158/1538-7445.Prca2017-A021 |
0.398 |
|
| 2018 |
Dhar D, Kumar D, Bagby S, Pitts TM, Messersmith WA, Raina K, Agarwal R. Abstract 277: Gaining insights into pancreatic cancer intervention with bitter melon, a natural agent, in combination with gemcitabine using patient derived xenografts Cancer Research. 78: 277-277. DOI: 10.1158/1538-7445.Am2018-277 |
0.368 |
|
| 2018 |
Raina K, Jain AK, Kumar D, Mohan V, Maroni P, Agarwal R. Abstract 272: Effect of inositol hexaphosphate on cancer stem cell pool of prostate tumors Cancer Research. 78: 272-272. DOI: 10.1158/1538-7445.Am2018-272 |
0.446 |
|
| 2017 |
Goswami DG, Kant R, Tewari-Singh N, Agarwal R. Efficacy of anti-inflammatory, antibiotic and pleiotropic agents in reversing nitrogen mustard-induced injury in ex vivo cultured rabbit cornea. Toxicology Letters. PMID 29174984 DOI: 10.1016/J.Toxlet.2017.11.026 |
0.334 |
|
| 2017 |
Goswami DG, Agarwal R, Tewari-Singh N. Phosgene Oxime: Injury and associated Mechanisms compared to vesicating agents Sulfur Mustard and Lewisite. Toxicology Letters. PMID 29141200 DOI: 10.1016/J.Toxlet.2017.11.011 |
0.333 |
|
| 2017 |
Tewari-Singh N, Goswami DG, Kant R, Ammar DA, Kumar D, Enzenauer RW, Casillas RP, Croutch CR, Petrash JM, Agarwal R. Histopathological and Molecular Changes in the rabbit cornea from Arsenical Vesicant Lewisite Exposure. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 28973427 DOI: 10.1093/Toxsci/Kfx198 |
0.314 |
|
| 2017 |
Kumar R, Deep G, Wempe MF, Surek J, Kumar A, Agarwal R, Agarwal C. Procyanidin B2 3,3"-di-O-gallate induces oxidative stress-mediated cell death in prostate cancer cells via inhibiting MAP kinase phosphatase activity and activating ERK1/2 and AMPK. Molecular Carcinogenesis. PMID 28876465 DOI: 10.1002/Mc.22731 |
0.464 |
|
| 2017 |
Punia R, Raina K, Agarwal R, Singh RP. Acacetin enhances the therapeutic efficacy of doxorubicin in non-small-cell lung carcinoma cells. Plos One. 12: e0182870. PMID 28859099 DOI: 10.1371/Journal.Pone.0182870 |
0.439 |
|
| 2017 |
Sinha N, Panda PK, Naik PP, Das DN, Mukhopadhyay S, Maiti TK, Shanmugam MK, Chinnathambi A, Zayed ME, Alharbi SA, Sethi G, Agarwal R, Bhutia SK. Abrus agglutinin promotes irreparable DNA damage by triggering ROS generation followed by ATM-p73 mediated apoptosis in oral squamous cell carcinoma. Molecular Carcinogenesis. PMID 28543759 DOI: 10.1002/Mc.22679 |
0.471 |
|
| 2017 |
da Silva RF, Nogueira-Pangrazi E, Kido LA, Montico F, Arana S, Kumar D, Raina K, Agarwal R, Cagnon VHA. Nintedanib antiangiogenic inhibitor effectiveness in delaying adenocarcinoma progression in Transgenic Adenocarcinoma of the Mouse Prostate (TRAMP). Journal of Biomedical Science. 24: 31. PMID 28499383 DOI: 10.1186/S12929-017-0334-Z |
0.387 |
|
| 2017 |
Dhar D, Raina K, Agarwal R. Mechanisms and Drug Targets for Pancreatic Cancer Chemoprevention. Current Medicinal Chemistry. PMID 28322154 DOI: 10.2174/0929867324666170320120647 |
0.378 |
|
| 2017 |
Dheeraj A, Rigby CM, O'Bryant CL, Agarwal C, Singh RP, Deep G, Agarwal R. Silibinin Treatment Inhibits the Growth of Hedgehog Inhibitor Resistant Basal Cell Carcinoma Cells via Targeting EGFR-MAPK-Akt and Hedgehog Signaling. Photochemistry and Photobiology. PMID 28120452 DOI: 10.1111/Php.12727 |
0.389 |
|
| 2017 |
Tewari-Singh N, Goswami DG, Kant R, Croutch CR, Casillas RP, Orlicky DJ, Agarwal R. Cutaneous exposure to vesicant phosgene oxime: Acute effects on the skin and systemic toxicity. Toxicology and Applied Pharmacology. PMID 28087322 DOI: 10.1016/J.Taap.2017.01.003 |
0.367 |
|
| 2017 |
Mukhopadhyay S, Schlaepfer IR, Bergman BC, Panda PK, Praharaj PP, Naik PP, Agarwal R, Bhutia SK. ATG14 facilitated lipophagy in cancer cells induce ER stress mediated mitoptosis through a ROS dependent pathway. Free Radical Biology & Medicine. PMID 28069524 DOI: 10.1016/J.Freeradbiomed.2017.01.007 |
0.387 |
|
| 2017 |
Dhar D, Deep G, Kumar S, Agarwal C, Serkova N, Wempe M, Raina K, Agarwal R. Abstract 1268: Bitter melon efficacy against human pancreatic cancer cells: possible involvement of cellular stemness and metabolome targets Cancer Research. 77: 1268-1268. DOI: 10.1158/1538-7445.Am2017-1268 |
0.389 |
|
| 2017 |
Agarwal C, Kumar D, Tyagi A, Serkova N, Wempe M, Raina K, Agarwal R. Abstract 1249: Procyanidin B2-3,3′-di-O-gallate targets cancer cell metabolism in its efficacy against human prostate carcinoma cells Cancer Research. 77: 1249-1249. DOI: 10.1158/1538-7445.Am2017-1249 |
0.365 |
|
| 2016 |
Naik PP, Das DN, Panda PK, Mukhopadhyay S, Sinha N, Praharaj PP, Agarwal R, Bhutia SK. Implications of cancer stem cells in developing therapeutic resistance in oral cancer. Oral Oncology. 62: 122-135. PMID 27865365 DOI: 10.1016/J.Oraloncology.2016.10.008 |
0.423 |
|
| 2016 |
Rigby CM, Roy S, Deep G, Guillermo-Lagae R, Jain AK, Dhar D, Orlicky DJ, Agarwal C, Agarwal R. Role of p53 in silibinin-mediated inhibition of ultraviolet B radiation-induced DNA damage, inflammation and skin carcinogenesis. Carcinogenesis. PMID 27729375 DOI: 10.1093/Carcin/Bgw106 |
0.398 |
|
| 2016 |
Qin JJ, Sarkar S, Voruganti S, Agarwal R, Wang W, Zhang R. Identification of lineariifolianoid A as a novel dual NFAT1 and MDM2 inhibitor for human cancer therapy. Journal of Biomedical Research. 30: 322-333. PMID 27533941 DOI: 10.7555/Jbr.30.20160018 |
0.496 |
|
| 2016 |
Deep G, Kumar R, Nambiar DK, Jain AK, Ramteke AM, Serkova NJ, Agarwal C, Agarwal R. Silibinin inhibits hypoxia-induced HIF-1α-mediated signaling, angiogenesis and lipogenesis in prostate cancer cells: In vitro evidence and in vivo functional imaging and metabolomics. Molecular Carcinogenesis. PMID 27533043 DOI: 10.1002/Mc.22537 |
0.44 |
|
| 2016 |
Raina K, Kumar S, Dhar D, Agarwal R. Silibinin and colorectal cancer chemoprevention: a comprehensive review on mechanisms and efficacy. Journal of Biomedical Research. 30. PMID 27476880 DOI: 10.7555/Jbr.30.20150111 |
0.375 |
|
| 2016 |
Raina K, Kumar D, Agarwal R. Promise of bitter melon (Momordica charantia) bioactives in cancer prevention and therapy. Seminars in Cancer Biology. PMID 27452666 DOI: 10.1016/J.Semcancer.2016.07.002 |
0.345 |
|
| 2016 |
Mohan V, Agarwal R, Singh RP. A novel alkaloid, evodiamine causes nuclear localization of cytochrome-c and induces apoptosis independent of p53 in human lung cancer cells. Biochemical and Biophysical Research Communications. PMID 27402273 DOI: 10.1016/J.Bbrc.2016.07.037 |
0.461 |
|
| 2016 |
Goswami DG, Tewari-Singh N, Agarwal R. Corneal toxicity induced by vesicating agents and effective treatment options. Annals of the New York Academy of Sciences. PMID 27327041 DOI: 10.1111/Nyas.13121 |
0.338 |
|
| 2016 |
Tewari-Singh N, Agarwal R. Mustard vesicating agent-induced toxicity in the skin tissue and silibinin as a potential countermeasure. Annals of the New York Academy of Sciences. PMID 27326543 DOI: 10.1111/Nyas.13099 |
0.368 |
|
| 2016 |
Sabarwal A, Agarwal R, Singh RP. Fisetin inhibits cellular proliferation and induces mitochondria-dependent apoptosis in human gastric cancer cells. Molecular Carcinogenesis. PMID 27254419 DOI: 10.1002/Mc.22512 |
0.445 |
|
| 2016 |
Ting H, Deep G, Kumar S, Jain AK, Agarwal C, Agarwal R. Beneficial effects of the naturally occurring flavonoid silibinin on the prostate cancer microenvironment: role of monocyte chemotactic protein-1 and immune cell recruitment. Carcinogenesis. PMID 27207648 DOI: 10.1093/Carcin/Bgw039 |
0.444 |
|
| 2016 |
Panda PK, Behera B, Meher BR, Das DN, Mukhopadhyay S, Sinha N, Naik PP, Roy B, Das J, Paul S, Maiti TK, Agarwal R, Bhutia SK. Abrus agglutinin, a type II ribosome inactivating protein inhibits Akt/PH domain to induce endoplasmic reticulum stress mediated autophagy-dependent cell death. Molecular Carcinogenesis. PMID 27182794 DOI: 10.1002/Mc.22502 |
0.421 |
|
| 2016 |
Qin JJ, Wang W, Sarkar S, Voruganti S, Agarwal R, Zhang R. Inulanolide A as a new dual inhibitor of NFAT1-MDM2 pathway for breast cancer therapy. Oncotarget. PMID 27105525 DOI: 10.18632/Oncotarget.8873 |
0.408 |
|
| 2016 |
Tewari-Singh N, Croutch CR, Tuttle R, Goswami DG, Kant R, Peters E, Culley T, Ammar DA, Enzenauer RW, Petrash JM, Casillas RP, Agarwal R. Clinical progression of ocular injury following arsenical vesicant lewisite exposure. Cutaneous and Ocular Toxicology. 1-10. PMID 27002633 DOI: 10.3109/15569527.2015.1127255 |
0.303 |
|
| 2016 |
Deep G, Kumar R, Jain AK, Dhar D, Panigrahi GK, Hussain A, Agarwal C, El-Elimat T, Sica VP, Oberlies NH, Agarwal R. Graviola inhibits hypoxia-induced NADPH oxidase activity in prostate cancer cells reducing their proliferation and clonogenicity. Scientific Reports. 6: 23135. PMID 26979487 DOI: 10.1038/Srep23135 |
0.441 |
|
| 2016 |
Raina K, Kumar D, Agarwal R, Agarwal C. Abstract A03: Procyanidin B2 3,3”-di-O-gallate from grape seed causes metabolic alterations in prostate cancer cells: 1H-, 13C- and 31P-NMRS-based metabolomics study Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Metca15-A03 |
0.414 |
|
| 2016 |
Agarwal R, Dhar D, Agarwal C, Deep G. Abstract 5236: Bitter melon juice causes strong efficacy towards pancreatic cancer stem cells by modulating the hedgehog signaling pathway Cancer Research. 76: 5236-5236. DOI: 10.1158/1538-7445.Am2016-5236 |
0.38 |
|
| 2016 |
Schlaepfer IR, Deep G, Agarwal R, Zhang Z, Salzmann-Sullivan M, Su L, Flaig T. Abstract 1055: CPT1A-mediated lipid catabolism modulates growth, AR expression and hypoxia survival of prostate cancer Cancer Research. 76: 1055-1055. DOI: 10.1158/1538-7445.Am2016-1055 |
0.414 |
|
| 2015 |
Goswami DG, Tewari-Singh N, Dhar D, Kumar D, Agarwal C, Ammar DA, Kant R, Enzenauer RW, Petrash JM, Agarwal R. Nitrogen Mustard-Induced Corneal Injury Involves DNA Damage and Pathways Related to Inflammation, Epithelial-Stromal Separation, and Neovascularization. Cornea. PMID 26555588 DOI: 10.1097/Ico.0000000000000685 |
0.362 |
|
| 2015 |
Nambiar D, Rajamani P, Deep G, Jain AK, Agarwal R, Singh RP. Silibinin preferentially radiosensitizes prostate cancer by inhibiting DNA repair signaling. Molecular Cancer Therapeutics. PMID 26516160 DOI: 10.1158/1535-7163.Mct-15-0348 |
0.462 |
|
| 2015 |
Guillermo-Lagae R, Deep G, Ting H, Agarwal C, Agarwal R. Silibinin enhances the repair of ultraviolet B-induced DNA damage by activating p53-dependent nucleotide excision repair mechanism in human dermal fibroblasts. Oncotarget. PMID 26447614 DOI: 10.18632/Oncotarget.5519 |
0.393 |
|
| 2015 |
Charepalli V, Reddivari L, Radhakrishnan S, Vadde R, Agarwal R, Vanamala JK. Anthocyanin-containing purple-fleshed potatoes suppress colon tumorigenesis via elimination of colon cancer stem cells. The Journal of Nutritional Biochemistry. PMID 26383537 DOI: 10.1016/J.Jnutbio.2015.08.005 |
0.47 |
|
| 2015 |
Kumar R, Deep G, Agarwal R. An Overview of Ultraviolet B Radiation-Induced Skin Cancer Chemoprevention by Silibinin. Current Pharmacology Reports. 1: 206-215. PMID 26097804 DOI: 10.1007/S40495-015-0027-9 |
0.436 |
|
| 2015 |
Schlaepfer IR, Nambiar DK, Ramteke A, Kumar R, Dhar D, Agarwal C, Bergman B, Graner M, Maroni P, Singh RP, Agarwal R, Deep G. Hypoxia induces triglycerides accumulation in prostate cancer cells and extracellular vesicles supporting growth and invasiveness following reoxygenation. Oncotarget. PMID 26087400 DOI: 10.18632/Oncotarget.4479 |
0.434 |
|
| 2015 |
Tilley C, Deep G, Agarwal R. Chemopreventive opportunities to control basal cell carcinoma: Current perspectives. Molecular Carcinogenesis. 54: 688-97. PMID 26053157 DOI: 10.1002/Mc.22348 |
0.349 |
|
| 2015 |
Kumar D, Tewari-Singh N, Agarwal C, Jain AK, Inturi S, Kant R, White CW, Agarwal R. Nitrogen mustard exposure of murine skin induces DNA damage, oxidative stress and activation of MAPK/Akt-AP1 pathway leading to induction of inflammatory and proteolytic mediators. Toxicology Letters. 235: 161-71. PMID 25891025 DOI: 10.1016/J.Toxlet.2015.04.006 |
0.788 |
|
| 2015 |
Jain AK, Tewari-Singh N, Inturi S, Kumar D, Orlicky DJ, Agarwal C, White CW, Agarwal R. Flavanone silibinin treatment attenuates nitrogen mustard-induced toxic effects in mouse skin. Toxicology and Applied Pharmacology. 285: 71-8. PMID 25791923 DOI: 10.1016/J.Taap.2015.03.009 |
0.786 |
|
| 2015 |
Somasagara RR, Deep G, Shrotriya S, Patel M, Agarwal C, Agarwal R. Bitter melon juice targets molecular mechanisms underlying gemcitabine resistance in pancreatic cancer cells. International Journal of Oncology. 46: 1849-57. PMID 25672620 DOI: 10.3892/Ijo.2015.2885 |
0.795 |
|
| 2015 |
Schlaepfer IR, Glodé LM, Hitz CA, Pac CT, Boyle KE, Maroni P, Deep G, Agarwal R, Lucia SM, Cramer SD, Serkova NJ, Eckel RH. Inhibition of Lipid Oxidation Increases Glucose Metabolism and Enhances 2-Deoxy-2-[(18)F]Fluoro-D-Glucose Uptake in Prostate Cancer Mouse Xenografts. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 17: 529-38. PMID 25561013 DOI: 10.1007/S11307-014-0814-4 |
0.303 |
|
| 2015 |
Kumar R, Deep G, Wempe MF, Agarwal R, Agarwal C. Procyanidin B2 3,3″-di-O-gallate inhibits endothelial cells growth and motility by targeting VEGFR2 and integrin signaling pathways. Current Cancer Drug Targets. 15: 14-26. PMID 25552257 DOI: 10.2174/1568009614666141229102254 |
0.442 |
|
| 2015 |
Goswami DG, Kumar D, Tewari-Singh N, Orlicky DJ, Jain AK, Kant R, Rancourt RC, Dhar D, Inturi S, Agarwal C, White CW, Agarwal R. Topical nitrogen mustard exposure causes systemic toxic effects in mice. Experimental and Toxicologic Pathology : Official Journal of the Gesellschaft FüR Toxikologische Pathologie. 67: 161-70. PMID 25481215 DOI: 10.1016/J.Etp.2014.11.006 |
0.758 |
|
| 2015 |
Shrotriya S, Agarwal R, Sclafani RA. A perspective on chemoprevention by resveratrol in head and neck squamous cell carcinoma. Advances in Experimental Medicine and Biology. 815: 333-48. PMID 25427916 DOI: 10.1007/978-3-319-09614-8_19 |
0.819 |
|
| 2015 |
Ramteke A, Ting H, Agarwal C, Mateen S, Somasagara R, Hussain A, Graner M, Frederick B, Agarwal R, Deep G. Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules. Molecular Carcinogenesis. 54: 554-65. PMID 24347249 DOI: 10.1002/Mc.22124 |
0.805 |
|
| 2015 |
Shrotriya S, Tyagi A, Deep G, Orlicky DJ, Wisell J, Wang XJ, Sclafani RA, Agarwal R, Agarwal C. Grape seed extract and resveratrol prevent 4-nitroquinoline 1-oxide induced oral tumorigenesis in mice by modulating AMPK activation and associated biological responses. Molecular Carcinogenesis. 54: 291-300. PMID 24243690 DOI: 10.1002/Mc.22099 |
0.804 |
|
| 2015 |
Raina K, Kumar S, Kumar D, Somasagara RR, Punia R, Kant R, Agarwal R, Agarwal C. Abstract 901: Grape seed extract decreases visceral adiposity and impairs the pro-tumorigenic adipose tissue secretions affecting colorectal cancer growth and progression Cancer Research. 75: 901-901. DOI: 10.1158/1538-7445.Am2015-901 |
0.353 |
|
| 2015 |
Nambiar DK, Rajamani P, Jain A, Deep G, Agarwal R, Singh RP. Abstract 3339: Silibinin improves radiotherapeutic efficacy in prostate cancer by reducing IR-induced toxicity and EMT Cancer Research. 75: 3339-3339. DOI: 10.1158/1538-7445.Am2015-3339 |
0.501 |
|
| 2015 |
Kumar S, Kumar D, Raina K, Serkova NJ, Agarwal C, Agarwal R. Abstract 2807: Oral silibinin inhibits tumorigenic potential of colon cancer stem cells Cancer Research. 75: 2807-2807. DOI: 10.1158/1538-7445.Am2015-2807 |
0.407 |
|
| 2014 |
Shrotriya S, Deep G, Lopert P, Patel M, Agarwal R, Agarwal C. Grape seed extract targets mitochondrial electron transport chain complex III and induces oxidative and metabolic stress leading to cytoprotective autophagy and apoptotic death in human head and neck cancer cells. Molecular Carcinogenesis. PMID 25557495 DOI: 10.1002/Mc.22246 |
0.804 |
|
| 2014 |
Tilley C, Deep G, Agarwal C, Wempe MF, Biedermann D, Valentová K, Kren V, Agarwal R. Silibinin and its 2,3-dehydro-derivative inhibit basal cell carcinoma growth via suppression of mitogenic signaling and transcription factors activation. Molecular Carcinogenesis. PMID 25492239 DOI: 10.1002/Mc.22253 |
0.49 |
|
| 2014 |
Nambiar DK, Deep G, Singh RP, Agarwal C, Agarwal R. Silibinin inhibits aberrant lipid metabolism, proliferation and emergence of androgen-independence in prostate cancer cells via primarily targeting the sterol response element binding protein 1. Oncotarget. 5: 10017-33. PMID 25294820 DOI: 10.18632/Oncotarget.2488 |
0.399 |
|
| 2014 |
Kumar S, Kumar D, Raina K, Agarwal R, Agarwal C. Functional modification of adipocytes by grape seed extract impairs their pro-tumorigenic signaling on colon cancer stem cells and the daughter cancer cells. Oncotarget. 5: 10151-69. PMID 25294814 DOI: 10.18632/Oncotarget.2467 |
0.409 |
|
| 2014 |
Deep G, Kumar R, Jain AK, Agarwal C, Agarwal R. Silibinin inhibits fibronectin induced motility, invasiveness and survival in human prostate carcinoma PC3 cells via targeting integrin signaling. Mutation Research. 768: 35-46. PMID 25285031 DOI: 10.1016/J.Mrfmmm.2014.05.002 |
0.46 |
|
| 2014 |
Kavitha CV, Jain AK, Agarwal C, Pierce A, Keating A, Huber KM, Serkova NJ, Wempe MF, Agarwal R, Deep G. Asiatic acid induces endoplasmic reticulum stress and apoptotic death in glioblastoma multiforme cells both in vitro and in vivo. Molecular Carcinogenesis. PMID 25252179 DOI: 10.1002/Mc.22220 |
0.442 |
|
| 2014 |
Kumar S, Raina K, Agarwal C, Agarwal R. Silibinin strongly inhibits the growth kinetics of colon cancer stem cell-enriched spheroids by modulating interleukin 4/6-mediated survival signals. Oncotarget. 5: 4972-89. PMID 24970802 DOI: 10.18632/Oncotarget.2068 |
0.396 |
|
| 2014 |
Tewari-Singh N, Inturi S, Jain AK, Agarwal C, Orlicky DJ, White CW, Agarwal R, Day BJ. Catalytic antioxidant AEOL 10150 treatment ameliorates sulfur mustard analog 2-chloroethyl ethyl sulfide-associated cutaneous toxic effects. Free Radical Biology & Medicine. 72: 285-95. PMID 24815113 DOI: 10.1016/J.Freeradbiomed.2014.04.022 |
0.799 |
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| 2014 |
Bauerle KT, Schweppe RE, Lund G, Kotnis G, Deep G, Agarwal R, Pozdeyev N, Wood WM, Haugen BR. Nuclear factor κB-dependent regulation of angiogenesis, and metastasis in an in vivo model of thyroid cancer is associated with secreted interleukin-8. The Journal of Clinical Endocrinology and Metabolism. 99: E1436-44. PMID 24758177 DOI: 10.1210/Jc.2013-3636 |
0.363 |
|
| 2014 |
Inturi S, Tewari-Singh N, Agarwal C, White CW, Agarwal R. Activation of DNA damage repair pathways in response to nitrogen mustard-induced DNA damage and toxicity in skin keratinocytes. Mutation Research. 763: 53-63. PMID 24732344 DOI: 10.1016/J.Mrfmmm.2014.04.002 |
0.786 |
|
| 2014 |
Derry MM, Somasagara RR, Raina K, Kumar S, Gomez J, Patel M, Agarwal R, Agarwal C. Target identification of grape seed extract in colorectal cancer using drug affinity responsive target stability (DARTS) technique: role of endoplasmic reticulum stress response proteins. Current Cancer Drug Targets. 14: 323-36. PMID 24724981 DOI: 10.2174/1568009614666140411101942 |
0.798 |
|
| 2014 |
Derry MM, Raina K, Agarwal R, Agarwal C. Characterization of azoxymethane-induced colon tumor metastasis to lung in a mouse model relevant to human sporadic colorectal cancer and evaluation of grape seed extract efficacy. Experimental and Toxicologic Pathology : Official Journal of the Gesellschaft FüR Toxikologische Pathologie. 66: 235-42. PMID 24670932 DOI: 10.1016/J.Etp.2014.02.003 |
0.793 |
|
| 2014 |
Jain AK, Tewari-Singh N, Inturi S, Orlicky DJ, White CW, Agarwal R. Myeloperoxidase deficiency attenuates nitrogen mustard-induced skin injuries. Toxicology. 320: 25-33. PMID 24631667 DOI: 10.1016/J.Tox.2014.02.013 |
0.777 |
|
| 2014 |
Ting HJ, Deep G, Jain AK, Cimic A, Sirintrapun J, Romero LM, Cramer SD, Agarwal C, Agarwal R. Silibinin prevents prostate cancer cell-mediated differentiation of naïve fibroblasts into cancer-associated fibroblast phenotype by targeting TGF β2. Molecular Carcinogenesis. PMID 24615813 DOI: 10.1002/Mc.22135 |
0.421 |
|
| 2014 |
Deep G, Jain AK, Ramteke A, Ting H, Vijendra KC, Gangar SC, Agarwal C, Agarwal R. SNAI1 is critical for the aggressiveness of prostate cancer cells with low E-cadherin. Molecular Cancer. 13: 37. PMID 24565133 DOI: 10.1186/1476-4598-13-37 |
0.354 |
|
| 2014 |
Tewari-Singh N, Jain AK, Orlicky DJ, White CW, Agarwal R. Cutaneous injury-related structural changes and their progression following topical nitrogen mustard exposure in hairless and haired mice. Plos One. 9: e85402. PMID 24416404 DOI: 10.1371/Journal.Pone.0085402 |
0.375 |
|
| 2014 |
Ting H, Deep G, Agarwal C, Agarwal R. The strategies to control prostate cancer by chemoprevention approaches. Mutation Research. 760: 1-15. PMID 24389535 DOI: 10.1016/J.Mrfmmm.2013.12.003 |
0.419 |
|
| 2014 |
Jain AK, Tewari-Singh N, Inturi S, Orlicky DJ, White CW, Agarwal R. Histopathological and immunohistochemical evaluation of nitrogen mustard-induced cutaneous effects in SKH-1 hairless and C57BL/6 mice. Experimental and Toxicologic Pathology : Official Journal of the Gesellschaft FüR Toxikologische Pathologie. 66: 129-38. PMID 24373750 DOI: 10.1016/J.Etp.2013.11.005 |
0.787 |
|
| 2014 |
Tyagi A, Raina K, Shrestha SP, Miller B, Thompson JA, Wempe MF, Agarwal R, Agarwal C. Procyanidin B2 3,3(″)-di-O-gallate, a biologically active constituent of grape seed extract, induces apoptosis in human prostate cancer cells via targeting NF-κB, Stat3, and AP1 transcription factors. Nutrition and Cancer. 66: 736-46. PMID 24191894 DOI: 10.1080/01635581.2013.783602 |
0.429 |
|
| 2014 |
Narayanapillai S, Agarwal C, Deep G, Agarwal R. Silibinin inhibits ultraviolet B radiation-induced DNA-damage and apoptosis by enhancing interleukin-12 expression in JB6 cells and SKH-1 hairless mouse skin. Molecular Carcinogenesis. 53: 471-9. PMID 23359305 DOI: 10.1002/Mc.22000 |
0.393 |
|
| 2014 |
Kavitha CV, Deep G, Gangar SC, Jain AK, Agarwal C, Agarwal R. Silibinin inhibits prostate cancer cells- and RANKL-induced osteoclastogenesis by targeting NFATc1, NF-κB, and AP-1 activation in RAW264.7 cells. Molecular Carcinogenesis. 53: 169-80. PMID 23115104 DOI: 10.1002/Mc.21959 |
0.433 |
|
| 2014 |
Somasagara R, Deep G, Shrotriya S, Patel M, Agarwal C, Agarwal R. Abstract 698A: Bitter melon juice targets molecular mechanisms underlying gemcitabine resistance in pancreatic cancer cells Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-698A |
0.408 |
|
| 2014 |
Kumar S, Kumar D, Raina K, Agarwal R, Agarwal C. Abstract 4116: Grape seed extract impairs adipocyte-colorectal cancer cell interaction and decreases adipocyte-driven colon cancer stem colonosphere formation Cancer Research. 74: 4116-4116. DOI: 10.1158/1538-7445.Am2014-4116 |
0.403 |
|
| 2014 |
Deep G, Ramteke AM, Nambiar DK, Jain AK, Serkova NJ, Agarwal C, Agarwal R. Abstract 4114: Silibinin inhibits hypoxia-induced proliferation, angiogenesis and lipogenesis in prostate cancer cells both in vitro and in vivo Cancer Research. 74: 4114-4114. DOI: 10.1158/1538-7445.Am2014-4114 |
0.453 |
|
| 2014 |
Nambiar DK, Deep G, Singh RP, Agarwal C, Agarwal R. Abstract 2452: Silibinin inhibits lipid metabolism by primarily targeting the master regulator sterol response element binding protein 1 (SREBP1) in prostate cancer cells Cancer Research. 74: 2452-2452. DOI: 10.1158/1538-7445.Am2014-2452 |
0.403 |
|
| 2014 |
Tyagi A, Somasagara R, Kumar S, Raina K, Agarwal C, Agarwal R. Abstract 2127: Silibinin modulates the inflammatory signals on colon cancer stem cells and provides protective effect against colitis-associated colon tumorigenesis Cancer Research. 74: 2127-2127. DOI: 10.1158/1538-7445.Am2014-2127 |
0.434 |
|
| 2014 |
Schlaepfer IR, Pac CT, Serkova NJ, Deep G, Agarwal R, Cramer SD, Eckel RH, Glode LM. Abstract 107: Lipid metabolism inhibitors enhance glycolysis and FDG-PET imaging of prostate cancer tumors Cancer Research. 74: 107-107. DOI: 10.1158/1538-7445.Am2014-107 |
0.368 |
|
| 2014 |
Kumar R, Deep G, Wempe M, Agarwal R, Agarwal C. Abstract 1012: Procyanidin B2 3,3″-di-O-gallate (B2G2), a biologically active constituent of grape seed extract, inhibits angiogenesis targeting multiple molecular pathways Cancer Research. 74: 1012-1012. DOI: 10.1158/1538-7445.Am2014-1012 |
0.486 |
|
| 2013 |
Bhat TA, Nambiar D, Tailor D, Pal A, Agarwal R, Singh RP. Acacetin inhibits in vitro and in vivo angiogenesis and downregulates Stat signaling and VEGF expression Cancer Prevention Research. 6: 1128-1139. PMID 23943785 DOI: 10.1158/1940-6207.Capr-13-0209 |
0.387 |
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| 2013 |
Inturi S, Tewari-Singh N, Jain AK, Roy S, White CW, Agarwal R. Absence of a p53 allele delays nitrogen mustard-induced early apoptosis and inflammation of murine skin. Toxicology. 311: 184-90. PMID 23845566 DOI: 10.1016/J.Tox.2013.06.013 |
0.793 |
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| 2013 |
Raina K, Tyagi A, Kumar D, Agarwal R, Agarwal C. Role of oxidative stress in cytotoxicity of grape seed extract in human bladder cancer cells. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 61: 187-95. PMID 23831192 DOI: 10.1016/J.Fct.2013.06.039 |
0.459 |
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| 2013 |
Tewari-Singh N, Jain AK, Inturi S, White CW, Agarwal R. Clinically-relevant cutaneous lesions by nitrogen mustard: useful biomarkers of vesicants skin injury in SKH-1 hairless and C57BL/6 mice. Plos One. 8: e67557. PMID 23826320 DOI: 10.1371/Journal.Pone.0067557 |
0.763 |
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| 2013 |
Forster GM, Raina K, Kumar A, Kumar S, Agarwal R, Chen MH, Bauer JE, McClung AM, Ryan EP. Rice varietal differences in bioactive bran components for inhibition of colorectal cancer cell growth. Food Chemistry. 141: 1545-52. PMID 23790950 DOI: 10.1016/J.Foodchem.2013.04.020 |
0.396 |
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| 2013 |
Raina K, Agarwal R. Promise and potential of silibinin in colorectal cancer management: what patterns can be seen? Future Oncology (London, England). 9: 759-61. PMID 23718291 DOI: 10.2217/Fon.13.51 |
0.31 |
|
| 2013 |
Tyagi A, Raina K, Gangar S, Kaur M, Agarwal R, Agarwal C. Differential effect of grape seed extract against human non-small-cell lung cancer cells: the role of reactive oxygen species and apoptosis induction. Nutrition and Cancer. 65: 44-53. PMID 23682782 DOI: 10.1080/01635581.2013.785003 |
0.461 |
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| 2013 |
Mateen S, Raina K, Agarwal R. Chemopreventive and anti-cancer efficacy of silibinin against growth and progression of lung cancer. Nutrition and Cancer. 65: 3-11. PMID 23682778 DOI: 10.1080/01635581.2013.785004 |
0.807 |
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| 2013 |
Agarwal R, Kale RK, Rao CV, Singh RP. Introduction to Special Issue on Molecular Basis for Cancer Prevention with Bioactive Food Components in Nutrition and Cancer--an International Journal. Nutrition and Cancer. 65: 1-2. PMID 23682777 DOI: 10.1080/01635581.2013.785012 |
0.404 |
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| 2013 |
Derry MM, Raina K, Agarwal C, Agarwal R. Identifying molecular targets of lifestyle modifications in colon cancer prevention. Frontiers in Oncology. 3: 119. PMID 23675573 DOI: 10.3389/Fonc.2013.00119 |
0.797 |
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| 2013 |
Derry MM, Raina K, Balaiya V, Jain AK, Shrotriya S, Huber KM, Serkova NJ, Agarwal R, Agarwal C. Grape seed extract efficacy against azoxymethane-induced colon tumorigenesis in A/J mice: interlinking miRNA with cytokine signaling and inflammation. Cancer Prevention Research (Philadelphia, Pa.). 6: 625-33. PMID 23639480 DOI: 10.1158/1940-6207.Capr-13-0053 |
0.796 |
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| 2013 |
Jain AK, Raina K, Agarwal R. Deletion of p21/Cdkn1a confers protective effect against prostate tumorigenesis in transgenic adenocarcinoma of the mouse prostate model. Cell Cycle (Georgetown, Tex.). 12: 1598-604. PMID 23624841 DOI: 10.4161/Cc.24741 |
0.344 |
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| 2013 |
Deep G, Agarwal R. Targeting tumor microenvironment with silibinin: promise and potential for a translational cancer chemopreventive strategy. Current Cancer Drug Targets. 13: 486-99. PMID 23617249 DOI: 10.2174/15680096113139990041 |
0.418 |
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| 2013 |
Ting H, Deep G, Agarwal R. Molecular mechanisms of silibinin-mediated cancer chemoprevention with major emphasis on prostate cancer. The Aaps Journal. 15: 707-16. PMID 23588585 DOI: 10.1208/S12248-013-9486-2 |
0.4 |
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| 2013 |
Agarwal C, Wadhwa R, Deep G, Biedermann D, Gažák R, Křen V, Agarwal R. Anti-cancer efficacy of silybin derivatives -- a structure-activity relationship. Plos One. 8: e60074. PMID 23555889 DOI: 10.1371/Journal.Pone.0060074 |
0.422 |
|
| 2013 |
Kaur M, Deep G, Jain AK, Raina K, Agarwal C, Wempe MF, Agarwal R. Bitter melon juice activates cellular energy sensor AMP-activated protein kinase causing apoptotic death of human pancreatic carcinoma cells. Carcinogenesis. 34: 1585-92. PMID 23475945 DOI: 10.1093/Carcin/Bgt081 |
0.458 |
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| 2013 |
Mateen S, Raina K, Agarwal C, Chan D, Agarwal R. Silibinin synergizes with histone deacetylase and DNA methyltransferase inhibitors in upregulating E-cadherin expression together with inhibition of migration and invasion of human non-small cell lung cancer cells. The Journal of Pharmacology and Experimental Therapeutics. 345: 206-14. PMID 23461975 DOI: 10.1124/Jpet.113.203471 |
0.801 |
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| 2013 |
Raina K, Agarwal C, Wadhwa R, Serkova NJ, Agarwal R. Energy deprivation by silibinin in colorectal cancer cells: a double-edged sword targeting both apoptotic and autophagic machineries. Autophagy. 9: 697-713. PMID 23445752 DOI: 10.4161/Auto.23960 |
0.489 |
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| 2013 |
Derry M, Raina K, Agarwal R, Agarwal C. Differential effects of grape seed extract against human colorectal cancer cell lines: the intricate role of death receptors and mitochondria. Cancer Letters. 334: 69-78. PMID 23268334 DOI: 10.1016/J.Canlet.2012.12.015 |
0.821 |
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| 2013 |
Sy-Cordero AA, Graf TN, Runyon SP, Wani MC, Kroll DJ, Agarwal R, Brantley SJ, Paine MF, Polyak SJ, Oberlies NH. Enhanced bioactivity of silybin B methylation products. Bioorganic & Medicinal Chemistry. 21: 742-7. PMID 23260576 DOI: 10.1016/J.Bmc.2012.11.035 |
0.344 |
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| 2013 |
Raina K, Ravichandran K, Rajamanickam S, Huber KM, Serkova NJ, Agarwal R. Inositol hexaphosphate inhibits tumor growth, vascularity, and metabolism in TRAMP mice: a multiparametric magnetic resonance study. Cancer Prevention Research (Philadelphia, Pa.). 6: 40-50. PMID 23213071 DOI: 10.1158/1940-6207.Capr-12-0387 |
0.349 |
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| 2013 |
Nambiar D, Prajapati V, Agarwal R, Singh RP. In vitro and in vivo anticancer efficacy of silibinin against human pancreatic cancer BxPC-3 and PANC-1 cells Cancer Letters. 334: 109-117. PMID 23022268 DOI: 10.1016/J.Canlet.2012.09.004 |
0.484 |
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| 2013 |
Raina K, Agarwal C, Agarwal R. Effect of silibinin in human colorectal cancer cells: targeting the activation of NF-κB signaling. Molecular Carcinogenesis. 52: 195-206. PMID 22086675 DOI: 10.1002/Mc.21843 |
0.405 |
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| 2013 |
Deep G, Jain AK, Mateen S, Vijendra KC, Gangar SC, Agarwal C, Agarwal R. Abstract C73: Src-beta catenin-SNAI1 axis is critical for the stemness and bone metastasis of E-cadherin-lacking prostate cancer cells Cancer Research. 73. DOI: 10.1158/1538-7445.Tim2013-C73 |
0.805 |
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| 2013 |
Kumar S, Raina K, Agarwal C, Agarwal R. Abstract 4877: Silibinin strongly modulates the cytokine interleukin-4/6 survival signals in colon cancer stem cells. Cancer Research. 73: 4877-4877. DOI: 10.1158/1538-7445.Am2013-4877 |
0.39 |
|
| 2013 |
Tilley C, Deep G, Agarwal C, Agarwal R. Abstract 3664: Silibinin induces cell cycle arrest and apoptotic death via targeting hedgehog signaling in basal cell carcinoma cells. Cancer Research. 73: 3664-3664. DOI: 10.1158/1538-7445.Am2013-3664 |
0.504 |
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| 2013 |
Jain AK, Raina K, Agarwal R. Abstract 306: Deletion of p21/Cdkn1a confers protective effect against prostate tumorigenesis in Transgenic Adenocarcinoma of the Mouse Prostate model. Cancer Research. 73: 306-306. DOI: 10.1158/1538-7445.Am2013-306 |
0.363 |
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| 2013 |
Tyagi A, Raina K, Kumar S, Agarwal R, Agarwal C. Abstract 2593: Procyanidin B2 3,3″-di-O-gallate causes strong efficacy towards prostate cancer stem cells via targeting Notch1 signaling. Cancer Research. 73: 2593-2593. DOI: 10.1158/1538-7445.Am2013-2593 |
0.448 |
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| 2013 |
Deep G, Ramteke A, Atilano-Roque A, Agarwal C, Agarwal R. Abstract 2587: Silibinin targets stemness and aberrant metabolic signaling in prostate cancer cells. Cancer Research. 73: 2587-2587. DOI: 10.1158/1538-7445.Am2013-2587 |
0.464 |
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| 2013 |
Ramasamy K, Deep G, Tyagi A, Agarwal C, Agarwal R. Abstract 2579: Silibinin inhibits tumor associated macrophages-induced lung cancer cell growth and invasiveness by down-regulating macrophage migration inhibitory factor . Cancer Research. 73: 2579-2579. DOI: 10.1158/1538-7445.Am2013-2579 |
0.39 |
|
| 2012 |
Tewari-Singh N, Jain AK, Inturi S, Agarwal C, White CW, Agarwal R. Silibinin attenuates sulfur mustard analog-induced skin injury by targeting multiple pathways connecting oxidative stress and inflammation. Plos One. 7: e46149. PMID 23029417 DOI: 10.1371/Journal.Pone.0046149 |
0.774 |
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| 2012 |
Henderson AJ, Ollila CA, Kumar A, Borresen EC, Raina K, Agarwal R, Ryan EP. Chemopreventive properties of dietary rice bran: current status and future prospects. Advances in Nutrition (Bethesda, Md.). 3: 643-53. PMID 22983843 DOI: 10.3945/An.112.002303 |
0.44 |
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| 2012 |
Mateen S, Raina K, Jain AK, Agarwal C, Chan D, Agarwal R. Epigenetic modifications and p21-cyclin B1 nexus in anticancer effect of histone deacetylase inhibitors in combination with silibinin on non-small cell lung cancer cells. Epigenetics. 7: 1161-72. PMID 22965008 DOI: 10.4161/Epi.22070 |
0.813 |
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| 2012 |
Tewari-Singh N, Jain AK, Inturi S, Ammar DA, Agarwal C, Tyagi P, Kompella UB, Enzenauer RW, Petrash JM, Agarwal R. Silibinin, dexamethasone, and doxycycline as potential therapeutic agents for treating vesicant-inflicted ocular injuries. Toxicology and Applied Pharmacology. 264: 23-31. PMID 22841772 DOI: 10.1016/J.Taap.2012.07.014 |
0.777 |
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| 2012 |
Shrotriya S, Gagan D, Ramasamy K, Raina K, Barbakadze V, Merlani M, Gogilashvili L, Amiranashvili L, Mulkijanyan K, Papadopoulos K, Agarwal C, Agarwal R. Poly[3-(3, 4-dihydroxyphenyl) glyceric acid] from Comfrey exerts anti-cancer efficacy against human prostate cancer via targeting androgen receptor, cell cycle arrest and apoptosis. Carcinogenesis. 33: 1572-80. PMID 22693258 DOI: 10.1093/carcin/bgs202 |
0.8 |
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| 2012 |
Deep G, Gangar SC, Rajamanickam S, Raina K, Gu M, Agarwal C, Oberlies NH, Agarwal R. Angiopreventive efficacy of pure flavonolignans from milk thistle extract against prostate cancer: targeting VEGF-VEGFR signaling. Plos One. 7: e34630. PMID 22514647 DOI: 10.1371/Journal.Pone.0034630 |
0.425 |
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| 2012 |
Sikka A, Kaur M, Agarwal C, Deep G, Agarwal R. Metformin suppresses growth of human head and neck squamous cell carcinoma via global inhibition of protein translation. Cell Cycle (Georgetown, Tex.). 11: 1374-82. PMID 22421144 DOI: 10.4161/Cc.19798 |
0.446 |
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| 2012 |
Shrotriya S, Deep G, Gu M, Kaur M, Jain AK, Inturi S, Agarwal R, Agarwal C. Generation of reactive oxygen species by grape seed extract causes irreparable DNA damage leading to G2/M arrest and apoptosis selectively in head and neck squamous cell carcinoma cells. Carcinogenesis. 33: 848-58. PMID 22266465 DOI: 10.1093/Carcin/Bgs019 |
0.811 |
|
| 2012 |
Roy S, Deep G, Agarwal C, Agarwal R. Silibinin prevents ultraviolet B radiation-induced epidermal damages in JB6 cells and mouse skin in a p53-GADD45α-dependent manner. Carcinogenesis. 33: 629-36. PMID 22166495 DOI: 10.1093/Carcin/Bgr299 |
0.463 |
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| 2012 |
Bhat TA, Nambiar D, Pal A, Agarwal R, Singh RP. Fisetin inhibits various attributes of angiogenesis in vitro and in vivo-implications for angioprevention Carcinogenesis. 33: 385-393. PMID 22139440 DOI: 10.1093/Carcin/Bgr282 |
0.414 |
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| 2012 |
Narayanapillai S, Agarwal C, Tilley C, Agarwal R. Silibinin is a potent sensitizer of UVA radiation-induced oxidative stress and apoptosis in human keratinocyte HaCaT cells. Photochemistry and Photobiology. 88: 1135-40. PMID 22118157 DOI: 10.1111/J.1751-1097.2011.01050.X |
0.456 |
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| 2012 |
Tyagi A, Agarwal C, Dwyer-Nield LD, Singh RP, Malkinson AM, Agarwal R. Silibinin modulates TNF-α and IFN-γ mediated signaling to regulate COX2 and iNOS expression in tumorigenic mouse lung epithelial LM2 cells. Molecular Carcinogenesis. 51: 832-42. PMID 21882257 DOI: 10.1002/Mc.20851 |
0.401 |
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| 2012 |
Mukhtar H, Zaidi S, Raza H, Agarwal R. Differential expression of glutathione-s-transferase isozymes in murine and human skin tumors. International Journal of Oncology. 6: 37-43. PMID 21556498 DOI: 10.3892/Ijo.6.1.37 |
0.36 |
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| 2012 |
Mohan R, Katiyar S, Khan S, Zaim M, Mukhtar H, Agarwal R. Protective effect of all trans retinoic acid against tumor promotion and progression in low- and high-risk protocols of mouse skin chemical carcinogenesis. International Journal of Oncology. 8: 1079-88. PMID 21544467 DOI: 10.3892/Ijo.8.6.1079 |
0.328 |
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| 2012 |
Agarwal R. Abstract CN08-03: Targeting Molecular Pathways in the Tumor Microenvironment: A holistic Approach for Cancer Chemoprevention Cancer Prevention Research. 5: CN08-03-CN08-03. DOI: 10.1158/1940-6207.Prev-12-Cn08-03 |
0.447 |
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| 2012 |
Ting HJ, Deep G, Agarwal C, Cramer SD, Romero LM, Agarwal R. Abstract A86: Silibinin inhibits prostate cancer and stromal cells interaction through targeting TGF and -smooth muscle actin Cancer Prevention Research. 5: A86-A86. DOI: 10.1158/1940-6207.Prev-12-A86 |
0.453 |
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| 2012 |
Tilley C, Roy S, Deep G, Agarwal C, Agarwal R. Abstract A85: Silibinin exerts its protective effects against UVB-induced photodamage and skin carcinogenesis through p53 Cancer Prevention Research. 5: A85-A85. DOI: 10.1158/1940-6207.Prev-12-A85 |
0.39 |
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| 2012 |
Derry MM, Raina K, Balaiya V, Jain A, Shrotriya S, Agarwal R, Agarwal C. Abstract A32: Chemopreventive potential of Grape Seed Extract in azoxymethane-induced colon tumorigenesis in the A/J mouse model: interlinking miRNA expression and inflammatory and cytokine signaling Cancer Prevention Research. 5: A32-A32. DOI: 10.1158/1940-6207.Prev-12-A32 |
0.795 |
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| 2012 |
Kumar S, Raina K, Agarwal C, Agarwal R. Abstract LB-179: Effect of silibinin on the growth kinetics of 3D tumor spheroids: Colorectal cancer cells enriched for cancer stem cell phenotype Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-179 |
0.461 |
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| 2012 |
Agarwal C, Raina K, Tyagi A, Shrotriya S, Patel A, Agarwal R. Abstract 598: Grape seed extract targets bladder cancer cells via initiating both apoptotic and autophagic machineries Cancer Research. 72: 598-598. DOI: 10.1158/1538-7445.Am2012-598 |
0.488 |
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| 2012 |
Deep G, Vijendra KC, Jain AK, Gangar SC, Agarwal C, Agarwal R. Abstract 3426: E-cadherin regulates ‘stemness’ and ‘bone metastasis’ of prostate cancer cells Cancer Research. 72: 3426-3426. DOI: 10.1158/1538-7445.Am2012-3426 |
0.424 |
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| 2012 |
Raina K, Kumar S, Tyagi A, Agarwal C, Agarwal R. Abstract 1637: Silibinin causes strong efficacy towards colon cancer stem cells by modulating IL-4 caused CD44 expression Cancer Research. 72: 1637-1637. DOI: 10.1158/1538-7445.Am2012-1637 |
0.398 |
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| 2012 |
Kaur M, Gu M, Agarwal C, Wempe M, Agarwal R. Abstract 1612: Bitter melon juice induces apoptotic death of human pancreatic carcinoma cells Cancer Research. 72: 1612-1612. DOI: 10.1158/1538-7445.Am2012-1612 |
0.508 |
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| 2012 |
Mateen S, Raina K, Agarwal C, Chan D, Agarwal R. Abstract 1608: Silibinin synergizes with histone deacetylase (HDAC) inhibitors in upregulating E-cadherin expression in non-small lung cancer (NSCLC) cells Cancer Research. 72: 1608-1608. DOI: 10.1158/1538-7445.Am2012-1608 |
0.441 |
|
| 2012 |
Shrotriya S, Deep G, Gu M, Kaur M, Jain AK, Inturi S, Agarwal R, Agarwal C. Abstract 1598: Grape seed extract induces irreparable DNA damage causing G2/M arrest and apoptosis selectively in head and neck squamous cell carcinoma cells: Potential involvement of reactive oxygen species Cancer Research. 72: 1598-1598. DOI: 10.1158/1538-7445.Am2012-1598 |
0.829 |
|
| 2012 |
Narayanapillai SC, Gu M, Agarwal C, Agarwal R. Abstract 1592: Silibinin inhibits UVB-induced DNA-damage and apoptosis by enhancing interleukin-12 expression in JB6 cells and SKH-1 mouse skin Cancer Research. 72: 1592-1592. DOI: 10.1158/1538-7445.Am2012-1592 |
0.409 |
|
| 2011 |
Inturi S, Tewari-Singh N, Gu M, Shrotriya S, Gomez J, Agarwal C, White CW, Agarwal R. Mechanisms of sulfur mustard analog 2-chloroethyl ethyl sulfide-induced DNA damage in skin epidermal cells and fibroblasts. Free Radical Biology & Medicine. 51: 2272-80. PMID 21920433 DOI: 10.1016/J.Freeradbiomed.2011.08.020 |
0.794 |
|
| 2011 |
Kavitha CV, Agarwal C, Agarwal R, Deep G. Asiatic acid inhibits pro-angiogenic effects of VEGF and human gliomas in endothelial cell culture models. Plos One. 6: e22745. PMID 21826202 DOI: 10.1371/Journal.Pone.0022745 |
0.406 |
|
| 2011 |
Jain AK, Tewari-Singh N, Gu M, Inturi S, White CW, Agarwal R. Sulfur mustard analog, 2-chloroethyl ethyl sulfide-induced skin injury involves DNA damage and induction of inflammatory mediators, in part via oxidative stress, in SKH-1 hairless mouse skin. Toxicology Letters. 205: 293-301. PMID 21722719 DOI: 10.1016/J.Toxlet.2011.06.019 |
0.781 |
|
| 2011 |
Tyagi A, Gu M, Takahata T, Frederick B, Agarwal C, Siriwardana S, Agarwal R, Sclafani RA. Resveratrol selectively induces DNA Damage, independent of Smad4 expression, in its efficacy against human head and neck squamous cell carcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 5402-11. PMID 21705453 DOI: 10.1158/1078-0432.Ccr-11-1072 |
0.344 |
|
| 2011 |
Deep G, Gangar SC, Agarwal C, Agarwal R. Role of E-cadherin in antimigratory and antiinvasive efficacy of silibinin in prostate cancer cells. Cancer Prevention Research (Philadelphia, Pa.). 4: 1222-32. PMID 21546539 DOI: 10.1158/1940-6207.Capr-10-0370 |
0.395 |
|
| 2011 |
Jain AK, Tewari-Singh N, Orlicky DJ, White CW, Agarwal R. 2-Chloroethyl ethyl sulfide causes microvesication and inflammation-related histopathological changes in male hairless mouse skin. Toxicology. 282: 129-38. PMID 21295104 DOI: 10.1016/J.Tox.2011.01.021 |
0.372 |
|
| 2011 |
Kaur M, Tyagi A, Singh RP, Sclafani RA, Agarwal R, Agarwal C. Grape seed extract upregulates p21 (Cip1) through redox-mediated activation of ERK1/2 and posttranscriptional regulation leading to cell cycle arrest in colon carcinoma HT29 cells. Molecular Carcinogenesis. 50: 553-62. PMID 21268136 DOI: 10.1002/Mc.20739 |
0.436 |
|
| 2011 |
Ramasamy K, Dwyer-Nield LD, Serkova NJ, Hasebroock KM, Tyagi A, Raina K, Singh RP, Malkinson AM, Agarwal R. Silibinin prevents lung tumorigenesis in wild-type but not in iNOS-/- mice: potential of real-time micro-CT in lung cancer chemoprevention studies. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 753-61. PMID 21148748 DOI: 10.1158/1078-0432.Ccr-10-2290 |
0.334 |
|
| 2011 |
Tewari-Singh N, Agarwal C, Huang J, Day BJ, White CW, Agarwal R. Efficacy of glutathione in ameliorating sulfur mustard analog-induced toxicity in cultured skin epidermal cells and in SKH-1 mouse skin in vivo. The Journal of Pharmacology and Experimental Therapeutics. 336: 450-9. PMID 20974699 DOI: 10.1124/Jpet.110.173708 |
0.443 |
|
| 2011 |
Derry M, Balaiya V, Jain A, Gu M, Shrotriya S, Agarwal R, Agarwal C. Abstract B40: Chemoprevention potential of grape seed extract in azoxymethane-induced colon tumorigenesis in the A/J mouse model Cancer Prevention Research. 4. DOI: 10.1158/1940-6207.Prev-11-B40 |
0.809 |
|
| 2011 |
Deep G, George A, Agarwal C, Agarwal R. Abstract 4598: Silibinin targets fibronectin-integrin interaction and actin remodeling towards inhibiting motility and proliferation of human prostate carcinoma PC3 cells Cancer Research. 71: 4598-4598. DOI: 10.1158/1538-7445.Am2011-4598 |
0.435 |
|
| 2011 |
Derry MM, Agarwal R, Agarwal C. Abstract 4594: Grape seed extract induces apoptosis in human colorectal carcinoma through modulation of death receptors and anti-apoptotic molecules Cancer Research. 71: 4594-4594. DOI: 10.1158/1538-7445.Am2011-4594 |
0.83 |
|
| 2011 |
Mateen S, Gu M, Jain A, Agarwal C, Chan D, Agarwal R. Abstract 4592: Anti-tumorigenic effects of silibinin in combination with histone dacetylase inhibitors (TSA and SAHA): Involvement of G2/M arrest and apoptotic cell death Cancer Research. 71: 4592-4592. DOI: 10.1158/1538-7445.Am2011-4592 |
0.829 |
|
| 2011 |
Tyagi A, Gu M, Fredrick B, Agarwal C, Siriwardana S, Agarwal R, Sclafani RA. Abstract 3708: Resveratrol induces DNA damage independent of Smad4 expression in its efficacy against human head and neck carcinoma cells Cancer Research. 71: 3708-3708. DOI: 10.1158/1538-7445.Am2011-3708 |
0.52 |
|
| 2011 |
Vijendra KC, Deep G, Harrison G, Glode M, Agarwal C, Agarwal R. Abstract 3695: Oligonol, a novel lychee fruit-derived low-molecular weight procyanidin extract, inhibits angiogenesis: Implications for its use as angiopreventive agent against cancer Cancer Research. 71: 3695-3695. DOI: 10.1158/1538-7445.Am2011-3695 |
0.472 |
|
| 2011 |
Vijendra KC, Agarwal C, Agarwal R, Deep G. Abstract 3690: Asiatic acid is an effective alternative agent targeting growth, angiogenesis and invasiveness of malignant gliomas Cancer Research. 71: 3690-3690. DOI: 10.1158/1538-7445.Am2011-3690 |
0.494 |
|
| 2010 |
Ravichandran K, Velmurugan B, Gu M, Singh RP, Agarwal R. Inhibitory effect of silibinin against azoxymethane-induced colon tumorigenesis in A/J mice. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 4595-606. PMID 20823143 DOI: 10.1158/1078-0432.Ccr-10-1213 |
0.415 |
|
| 2010 |
Deep G, Gangar SC, Oberlies NH, Kroll DJ, Agarwal R. Isosilybin A induces apoptosis in human prostate cancer cells via targeting Akt, NF-κB, and androgen receptor signaling. Molecular Carcinogenesis. 49: 902-12. PMID 20721970 DOI: 10.1002/Mc.20670 |
0.441 |
|
| 2010 |
Deep G, Agarwal R. Antimetastatic efficacy of silibinin: molecular mechanisms and therapeutic potential against cancer. Cancer Metastasis Reviews. 29: 447-63. PMID 20714788 DOI: 10.1007/S10555-010-9237-0 |
0.428 |
|
| 2010 |
Velmurugan B, Gangar SC, Kaur M, Tyagi A, Deep G, Agarwal R. Silibinin exerts sustained growth suppressive effect against human colon carcinoma SW480 xenograft by targeting multiple signaling molecules. Pharmaceutical Research. 27: 2085-97. PMID 20628792 DOI: 10.1007/S11095-010-0207-6 |
0.378 |
|
| 2010 |
Velmurugan B, Singh RP, Agarwal R, Agarwal C. Dietary-feeding of grape seed extract prevents azoxymethane-induced colonic aberrant crypt foci formation in fischer 344 rats. Molecular Carcinogenesis. 49: 641-52. PMID 20564341 DOI: 10.1002/Mc.20643 |
0.41 |
|
| 2010 |
Tewari-Singh N, Gu M, Agarwal C, White CW, Agarwal R. Biological and molecular mechanisms of sulfur mustard analogue-induced toxicity in JB6 and HaCaT cells: possible role of ataxia telangiectasia-mutated/ataxia telangiectasia-Rad3-related cell cycle checkpoint pathway. Chemical Research in Toxicology. 23: 1034-44. PMID 20469912 DOI: 10.1021/Tx100038B |
0.473 |
|
| 2010 |
Kaur M, Velmurugan B, Tyagi A, Agarwal C, Singh RP, Agarwal R. Silibinin suppresses growth of human colorectal carcinoma SW480 cells in culture and xenograft through down-regulation of beta-catenin-dependent signaling. Neoplasia (New York, N.Y.). 12: 415-24. PMID 20454513 DOI: 10.1593/Neo.10188 |
0.357 |
|
| 2010 |
Redente EF, Dwyer-Nield LD, Merrick DT, Raina K, Agarwal R, Pao W, Rice PL, Shroyer KR, Malkinson AM. Tumor progression stage and anatomical site regulate tumor-associated macrophage and bone marrow-derived monocyte polarization. The American Journal of Pathology. 176: 2972-85. PMID 20431028 DOI: 10.2353/Ajpath.2010.090879 |
0.333 |
|
| 2010 |
Rajamanickam S, Velmurugan B, Kaur M, Singh RP, Agarwal R. Chemoprevention of intestinal tumorigenesis in APCmin/+ mice by silibinin. Cancer Research. 70: 2368-78. PMID 20215518 DOI: 10.1158/0008-5472.Can-09-3249 |
0.414 |
|
| 2010 |
Flaig TW, Glodé M, Gustafson D, Van Bokhoven A, Tao Y, Wilson S, Su LJ, Li Y, Harrison G, Agarwal R, Crawford ED, Lucia MS, Pollak M. A study of high-dose oral silybin-phytosome followed by prostatectomy in patients with localized prostate cancer Prostate. 70: 848-855. PMID 20127732 DOI: 10.1002/Pros.21118 |
0.313 |
|
| 2010 |
Velmurugan B, Singh RP, Kaul N, Agarwal R, Agarwal C. Dietary feeding of grape seed extract prevents intestinal tumorigenesis in APCmin/+ mice. Neoplasia (New York, N.Y.). 12: 95-102. PMID 20072658 DOI: 10.1593/Neo.91718 |
0.405 |
|
| 2010 |
Ling H, Jia X, Zhang Y, Gapter LA, Lim YS, Agarwal R, Ng KY. Pachymic acid inhibits cell growth and modulates arachidonic acid metabolism in nonsmall cell lung cancer A549 cells. Molecular Carcinogenesis. 49: 271-82. PMID 19918789 DOI: 10.1002/Mc.20597 |
0.407 |
|
| 2010 |
Mateen S, Tyagi A, Agarwal C, Singh RP, Agarwal R. Silibinin inhibits human nonsmall cell lung cancer cell growth through cell-cycle arrest by modulating expression and function of key cell-cycle regulators. Molecular Carcinogenesis. 49: 247-58. PMID 19908243 DOI: 10.1002/Mc.20595 |
0.818 |
|
| 2010 |
Gu M, Raina K, Agarwal C, Agarwal R. Inositol hexaphosphate downregulates both constitutive and ligand-induced mitogenic and cell survival signaling, and causes caspase-mediated apoptotic death of human prostate carcinoma PC-3 cells. Molecular Carcinogenesis. 49: 1-12. PMID 19544333 DOI: 10.1002/Mc.20560 |
0.412 |
|
| 2010 |
Singh RP, Bhat TA, Nambiar D, Balaiya V, Agarwal R. Abstract LB-428: Decursin inhibits advanced human prostate tumor xenograft growth involving antiproliferative and antiangiogenic mechanisms Cancer Research. 70. DOI: 10.1158/1538-7445.Am10-Lb-428 |
0.481 |
|
| 2010 |
Raina K, Ravichandran K, Rajamanickam S, Hasebroock KM, Serkova NJ, Agarwal R. Abstract 950: Energy deprivation by Inositol Hexaphosphate inhibits prostate tumor growth and progression in TRAMP mice Cancer Research. 70: 950-950. DOI: 10.1158/1538-7445.Am10-950 |
0.384 |
|
| 2010 |
Ramasamy K, Nield LD, Serkova NJ, Hasebroock KM, Tyagi A, Raina K, Malkinson AM, Agarwal R. Abstract 948: Silibinin selectively inhibits growth and progression of urethane-induced lung tumors in wild-type but not inducible nitric oxide synthase (-/-) mice: potential usefulness of micro-computed tomography scanning in lung cancer chemoprevention studies Cancer Research. 70: 948-948. DOI: 10.1158/1538-7445.Am10-948 |
0.4 |
|
| 2010 |
Derry MM, Kaur M, Agarwal R, Agarwal C. Abstract 5721: Grape seed extract induces both intrinsic and extrinsic apoptotic pathways in its efficacy against human colorectal cancer cells harboring varying degrees of metastatic potential Cancer Research. 70: 5721-5721. DOI: 10.1158/1538-7445.Am10-5721 |
0.473 |
|
| 2010 |
Agarwal C, Raina K, Agarwal R. Abstract 5692: Anti-inflammatory effects of silibinin in colorectal cancer: Targeting the activation of NF-κB signaling Cancer Research. 70: 5692-5692. DOI: 10.1158/1538-7445.Am10-5692 |
0.445 |
|
| 2010 |
Tyagi A, Gangar SC, Raina K, Agarwal R, Agarwal C. Abstract 5687: Grape seed extract induces apoptosis via reactive oxygen species-dependent mechanism in human non-small-cell lung cancer cells Cancer Research. 70: 5687-5687. DOI: 10.1158/1538-7445.Am10-5687 |
0.49 |
|
| 2010 |
Gangar SC, Deep G, Agarwal R. Abstract 5661: Silibinin inhibits advanced human prostate carcinoma-induced osteoclastogenesis Cancer Research. 70: 5661-5661. DOI: 10.1158/1538-7445.Am10-5661 |
0.445 |
|
| 2010 |
Deep G, Gangar SC, Agarwal R. Abstract 5650: Silibinin inhibits epithelial to mesenchymal transition in prostate cancer cells: Role of E-cadherin and beyond Cancer Research. 70: 5650-5650. DOI: 10.1158/1538-7445.Am10-5650 |
0.433 |
|
| 2010 |
Mateen S, Raina K, Agarwal C, Agarwal R. Abstract 3796: Inhibition of epigenetic chromatin-modification enzymes: histone deacetylases and DNA methyltransferases by silibinin in human NSCLC H1299 cells Cancer Research. 70: 3796-3796. DOI: 10.1158/1538-7445.Am10-3796 |
0.816 |
|
| 2010 |
Raina K, Agarwal C, Serkova NJ, Agarwal R. Abstract 3790: Molecular mechanism of cell death by silibinin in colorectal cancer: Apoptosis versus autophagy Cancer Research. 70: 3790-3790. DOI: 10.1158/1538-7445.Am10-3790 |
0.493 |
|
| 2010 |
Shrotriya S, Agarwal C, Agarwal R. Abstract 1876: Grape seed extract targets TGFβ/Smad signaling in its potential efficacy against human head and neck cancer cells Cancer Research. 70: 1876-1876. DOI: 10.1158/1538-7445.Am10-1876 |
0.455 |
|
| 2009 |
Gu M, Roy S, Raina K, Agarwal C, Agarwal R. Inositol hexaphosphate suppresses growth and induces apoptosis in prostate carcinoma cells in culture and nude mouse xenograft: PI3K-Akt pathway as potential target. Cancer Research. 69: 9465-72. PMID 19920184 DOI: 10.1158/0008-5472.Can-09-2805 |
0.455 |
|
| 2009 |
Pal A, Tewari-Singh N, Gu M, Agarwal C, Huang J, Day BJ, White CW, Agarwal R. Sulfur mustard analog induces oxidative stress and activates signaling cascades in the skin of SKH-1 hairless mice. Free Radical Biology & Medicine. 47: 1640-51. PMID 19761830 DOI: 10.1016/J.Freeradbiomed.2009.09.011 |
0.384 |
|
| 2009 |
Singh RP, Agarwal R. Cosmeceuticals and silibinin. Clinics in Dermatology. 27: 479-84. PMID 19695480 DOI: 10.1016/J.Clindermatol.2009.05.012 |
0.323 |
|
| 2009 |
Kaur M, Agarwal C, Agarwal R. Anticancer and cancer chemopreventive potential of grape seed extract and other grape-based products. The Journal of Nutrition. 139: 1806S-12S. PMID 19640973 DOI: 10.3945/Jn.109.106864 |
0.394 |
|
| 2009 |
Kaur M, Velmurugan B, Tyagi A, Deep G, Katiyar S, Agarwal C, Agarwal R. Silibinin suppresses growth and induces apoptotic death of human colorectal carcinoma LoVo cells in culture and tumor xenograft. Molecular Cancer Therapeutics. 8: 2366-74. PMID 19638451 DOI: 10.1158/1535-7163.Mct-09-0304 |
0.482 |
|
| 2009 |
Kaur M, Velmurugan B, Rajamanickam S, Agarwal R, Agarwal C. Gallic acid, an active constituent of grape seed extract, exhibits anti-proliferative, pro-apoptotic and anti-tumorigenic effects against prostate carcinoma xenograft growth in nude mice. Pharmaceutical Research. 26: 2133-40. PMID 19543955 DOI: 10.1007/S11095-009-9926-Y |
0.397 |
|
| 2009 |
Raina K, Serkova NJ, Agarwal R. Silibinin Feeding Alters the Metabolic Profile in TRAMP Prostatic Tumors: 1H-NMRS–Based Metabolomics Study Cancer Research. 69: 3731-3735. PMID 19366793 DOI: 10.1158/0008-5472.Can-09-0096 |
0.319 |
|
| 2009 |
Kang TJ, Lee SY, Singh RP, Agarwal R, Yim DS. Anti-tumor activity of oxypeucedanin from Ostericum koreanum against human prostate carcinoma DU145 cells. Acta Oncologica (Stockholm, Sweden). 48: 895-900. PMID 19322700 DOI: 10.1080/02841860902824925 |
0.44 |
|
| 2009 |
Roy S, Gu M, Ramasamy K, Singh RP, Agarwal C, Siriwardana S, Sclafani RA, Agarwal R. p21/Cip1 and p27/Kip1 Are essential molecular targets of inositol hexaphosphate for its antitumor efficacy against prostate cancer. Cancer Research. 69: 1166-73. PMID 19176374 DOI: 10.1158/0008-5472.Can-08-3115 |
0.383 |
|
| 2009 |
Singh RP, Raina K, Deep G, Chan D, Agarwal R. Silibinin suppresses growth of human prostate carcinoma PC-3 orthotopic xenograft via activation of extracellular signal-regulated kinase 1/2 and inhibition of signal transducers and activators of transcription signaling. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 613-21. PMID 19147767 DOI: 10.1158/1078-0432.Ccr-08-1846 |
0.344 |
|
| 2009 |
Tyagi A, Singh RP, Ramasamy K, Raina K, Redente EF, Dwyer-Nield LD, Radcliffe RA, Malkinson AM, Agarwal R. Growth inhibition and regression of lung tumors by silibinin: modulation of angiogenesis by macrophage-associated cytokines and nuclear factor-kappaB and signal transducers and activators of transcription 3. Cancer Prevention Research (Philadelphia, Pa.). 2: 74-83. PMID 19139021 DOI: 10.1158/1940-6207.Capr-08-0095 |
0.372 |
|
| 2009 |
Agarwal R, Deep G. Kava, a tonic for relieving the irrational development of natural preventive agents. Cancer Prevention Research (Philadelphia, Pa.). 1: 409-12. PMID 19138987 DOI: 10.1158/1940-6207.Capr-08-0172 |
0.34 |
|
| 2009 |
Tewari-Singh N, Rana S, Gu M, Pal A, Orlicky DJ, White CW, Agarwal R. Inflammatory biomarkers of sulfur mustard analog 2-chloroethyl ethyl sulfide-induced skin injury in SKH-1 hairless mice. Toxicological Sciences : An Official Journal of the Society of Toxicology. 108: 194-206. PMID 19075041 DOI: 10.1093/Toxsci/Kfn261 |
0.406 |
|
| 2009 |
Ling H, Zhou L, Jia X, Gapter LA, Agarwal R, Ng KY. Polyporenic acid C induces caspase-8-mediated apoptosis in human lung cancer A549 cells. Molecular Carcinogenesis. 48: 498-507. PMID 18973184 DOI: 10.1002/Mc.20487 |
0.455 |
|
| 2009 |
Raina K, Agarwal R. Combinatorial strategies for cancer eradication by silibinin and cytotoxic agents: efficacy and mechanisms. Acta Pharmacologica Sinica. 28: 1466-75. PMID 17723180 DOI: 10.1111/J.1745-7254.2007.00691.X |
0.402 |
|
| 2008 |
Rajamanickam S, Agarwal R. Natural products and colon cancer: current status and future prospects. Drug Development Research. 69: 460-471. PMID 19884979 DOI: 10.1002/Ddr.20276 |
0.403 |
|
| 2008 |
Velmurugan B, Singh RP, Tyagi A, Agarwal R. Inhibition of azoxymethane-induced colonic aberrant crypt foci formation by silibinin in male Fisher 344 rats. Cancer Prevention Research (Philadelphia, Pa.). 1: 376-84. PMID 19138982 DOI: 10.1158/1940-6207.Capr-08-0059 |
0.45 |
|
| 2008 |
Singh RP, Raina K, Sharma G, Agarwal R. Silibinin inhibits established prostate tumor growth, progression, invasion, and metastasis and suppresses tumor angiogenesis and epithelial-mesenchymal transition in transgenic adenocarcinoma of the mouse prostate model mice. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 7773-80. PMID 19047104 DOI: 10.1158/1078-0432.Ccr-08-1309 |
0.33 |
|
| 2008 |
Kaur M, Mandair R, Agarwal R, Agarwal C. Grape seed extract induces cell cycle arrest and apoptosis in human colon carcinoma cells. Nutrition and Cancer. 60: 2-11. PMID 19003575 DOI: 10.1080/01635580802381295 |
0.434 |
|
| 2008 |
Zhou L, Zhang Y, Gapter LA, Ling H, Agarwal R, Ng KY. Cytotoxic and anti-oxidant activities of lanostane-type triterpenes isolated from Poria cocos. Chemical & Pharmaceutical Bulletin. 56: 1459-62. PMID 18827390 DOI: 10.1248/Cpb.56.1459 |
0.311 |
|
| 2008 |
Deep G, Raina K, Singh RP, Oberlies NH, Kroll DJ, Agarwal R. Isosilibinin inhibits advanced human prostate cancer growth in athymic nude mice: comparison with silymarin and silibinin. International Journal of Cancer. 123: 2750-8. PMID 18798272 DOI: 10.1002/Ijc.23879 |
0.428 |
|
| 2008 |
Raina K, Rajamanickam S, Singh RP, Deep G, Chittezhath M, Agarwal R. Stage-specific inhibitory effects and associated mechanisms of silibinin on tumor progression and metastasis in transgenic adenocarcinoma of the mouse prostate model. Cancer Research. 68: 6822-30. PMID 18701508 DOI: 10.1158/0008-5472.Can-08-1332 |
0.359 |
|
| 2008 |
Chittezhath M, Deep G, Singh RP, Agarwal C, Agarwal R. Silibinin inhibits cytokine-induced signaling cascades and down-regulates inducible nitric oxide synthase in human lung carcinoma A549 cells. Molecular Cancer Therapeutics. 7: 1817-26. PMID 18644994 DOI: 10.1158/1535-7163.Mct-08-0256 |
0.41 |
|
| 2008 |
Roy S, Singh RP, Agarwal C, Siriwardana S, Sclafani R, Agarwal R. Downregulation of both p21/Cip1 and p27/Kip1 produces a more aggressive prostate cancer phenotype. Cell Cycle (Georgetown, Tex.). 7: 1828-35. PMID 18583941 DOI: 10.4161/Cc.7.12.6024 |
0.36 |
|
| 2008 |
Raina K, Rajamanickam S, Singh RP, Agarwal R. Chemopreventive efficacy of inositol hexaphosphate against prostate tumor growth and progression in TRAMP mice. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 3177-84. PMID 18483386 DOI: 10.1158/1078-0432.Ccr-07-5275 |
0.31 |
|
| 2008 |
Ramasamy K, Agarwal R. Multitargeted therapy of cancer by silymarin Cancer Letters. 269: 352-362. PMID 18472213 DOI: 10.1016/J.Canlet.2008.03.053 |
0.45 |
|
| 2008 |
Raina K, Rajamanickam S, Deep G, Singh M, Agarwal R, Agarwal C. Chemopreventive effects of oral gallic acid feeding on tumor growth and progression in TRAMP mice. Molecular Cancer Therapeutics. 7: 1258-67. PMID 18445658 DOI: 10.1158/1535-7163.Mct-07-2220 |
0.394 |
|
| 2008 |
Deep G, Oberlies NH, Kroll DJ, Agarwal R. Identifying the differential effects of silymarin constituents on cell growth and cell cycle regulatory molecules in human prostate cancer cells. International Journal of Cancer. 123: 41-50. PMID 18435416 DOI: 10.1002/Ijc.23485 |
0.429 |
|
| 2008 |
Singh RP, Gu M, Agarwal R. Silibinin inhibits colorectal cancer growth by inhibiting tumor cell proliferation and angiogenesis. Cancer Research. 68: 2043-50. PMID 18339887 DOI: 10.1158/0008-5472.Can-07-6247 |
0.415 |
|
| 2008 |
Deep G, Oberlies NH, Kroll DJ, Agarwal R. Isosilybin B causes androgen receptor degradation in human prostate carcinoma cells via PI3K-Akt-Mdm2-mediated pathway Oncogene. 27: 3986-3998. PMID 18332867 DOI: 10.1038/Onc.2008.45 |
0.358 |
|
| 2008 |
Anwar A, Gu M, Brady S, Qamar L, Behbakht K, Shellman YG, Agarwal R, Norris DA, Horwitz LD, Fujita M. Photoprotective effects of bucillamine against UV-induced damage in an SKH-1 hairless mouse model. Photochemistry and Photobiology. 84: 477-83. PMID 18266821 DOI: 10.1111/J.1751-1097.2007.00288.X |
0.396 |
|
| 2008 |
Tyagi A, Sharma Y, Agarwal C, Agarwal R. Silibinin impairs constitutively active TGFalpha-EGFR autocrine loop in advanced human prostate carcinoma cells. Pharmaceutical Research. 25: 2143-50. PMID 18253818 DOI: 10.1007/S11095-008-9545-Z |
0.372 |
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| 2008 |
Singh RP, Tyagi A, Sharma G, Mohan S, Agarwal R. Oral silibinin inhibits in vivo human bladder tumor xenograft growth involving down-regulation of survivin. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 300-8. PMID 18172282 DOI: 10.1158/1078-0432.Ccr-07-1565 |
0.418 |
|
| 2008 |
Graf TN, Pappa A, Nakanishi Y, Oberlies NH, Agarwal R, Kroll DJ. Pure Flavonolignans from Extracts of Milk Thistle (Silybum marianum) Against Models of Human Prostate Cancer Planta Medica. 74. DOI: 10.1055/S-2008-1075191 |
0.319 |
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| 2007 |
Tyagi A, Raina K, Singh RP, Gu M, Agarwal C, Harrison G, Glode LM, Agarwal R. Chemopreventive effects of silymarin and silibinin on N-butyl-N-(4-hydroxybutyl) nitrosamine induced urinary bladder carcinogenesis in male ICR mice. Molecular Cancer Therapeutics. 6: 3248-55. PMID 18089718 DOI: 10.1158/1535-7163.Mct-07-2006 |
0.451 |
|
| 2007 |
Raina K, Blouin MJ, Singh RP, Majeed N, Deep G, Varghese L, Glodé LM, Greenberg NM, Hwang D, Cohen P, Pollak MN, Agarwal R. Dietary feeding of silibinin inhibits prostate tumor growth and progression in transgenic adenocarcinoma of the mouse prostate model. Cancer Research. 67: 11083-91. PMID 18006855 DOI: 10.1158/0008-5472.Can-07-2222 |
0.399 |
|
| 2007 |
Kaur M, Agarwal R. Transcription factors: Molecular targets for prostate cancer intervention by phytochemicals Current Cancer Drug Targets. 7: 355-367. PMID 17979630 DOI: 10.2174/156800907780809732 |
0.414 |
|
| 2007 |
Graf TN, Wani MC, Agarwal R, Kroll DJ, Oberlies NH. Gram-scale purification of flavonolignan diastereoisomers from Silybum marianum (Milk Thistle) extract in support of preclinical in vivo studies for prostate cancer chemoprevention. Planta Medica. 73: 1495-501. PMID 17948171 DOI: 10.1055/S-2007-990239 |
0.314 |
|
| 2007 |
Roy S, Kaur M, Agarwal C, Tecklenburg M, Sclafani RA, Agarwal R. p21 and p27 induction by silibinin is essential for its cell cycle arrest effect in prostate carcinoma cells. Molecular Cancer Therapeutics. 6: 2696-707. PMID 17938263 DOI: 10.1158/1535-7163.Mct-07-0104 |
0.378 |
|
| 2007 |
Singh RP, Deep G, Blouin MJ, Pollak MN, Agarwal R. Silibinin suppresses in vivo growth of human prostate carcinoma PC-3 tumor xenograft. Carcinogenesis. 28: 2567-74. PMID 17916909 DOI: 10.1093/Carcin/Bgm218 |
0.418 |
|
| 2007 |
Singh RP, Agarwal R. Inducible nitric oxide synthase-vascular endothelial growth factor axis: a potential target to inhibit tumor angiogenesis by dietary agents. Current Cancer Drug Targets. 7: 475-83. PMID 17691907 DOI: 10.2174/156800907781386632 |
0.333 |
|
| 2007 |
Raina K, Singh RP, Agarwal R, Agarwal C. Oral grape seed extract inhibits prostate tumor growth and progression in TRAMP mice. Cancer Research. 67: 5976-82. PMID 17575168 DOI: 10.1158/0008-5472.Can-07-0295 |
0.409 |
|
| 2007 |
Deep G, Agarwal R. Chemopreventive efficacy of silymarin in skin and prostate cancer. Integrative Cancer Therapies. 6: 130-45. PMID 17548792 DOI: 10.1177/1534735407301441 |
0.431 |
|
| 2007 |
Gu M, Singh RP, Dhanalakshmi S, Agarwal C, Agarwal R. Silibinin inhibits inflammatory and angiogenic attributes in photocarcinogenesis in SKH-1 hairless mice. Cancer Research. 67: 3483-91. PMID 17409458 DOI: 10.1158/0008-5472.Can-06-3955 |
0.43 |
|
| 2007 |
Deep G, Oberlies NH, Kroll DJ, Agarwal R. Isosilybin B and isosilybin A inhibit growth, induce G1 arrest and cause apoptosis in human prostate cancer LNCaP and 22Rv1 cells. Carcinogenesis. 28: 1533-42. PMID 17389612 DOI: 10.1093/Carcin/Bgm069 |
0.434 |
|
| 2007 |
Agarwal C, Tyagi A, Kaur M, Agarwal R. Silibinin inhibits constitutive activation of Stat3, and causes caspase activation and apoptotic death of human prostate carcinoma DU145 cells. Carcinogenesis. 28: 1463-70. PMID 17341659 DOI: 10.1093/Carcin/Bgm042 |
0.426 |
|
| 2007 |
Agarwal C, Veluri R, Kaur M, Chou SC, Thompson JA, Agarwal R. Fractionation of high molecular weight tannins in grape seed extract and identification of procyanidin B2-3,3'-di-O-gallate as a major active constituent causing growth inhibition and apoptotic death of DU145 human prostate carcinoma cells. Carcinogenesis. 28: 1478-84. PMID 17331955 DOI: 10.1093/Carcin/Bgm045 |
0.372 |
|
| 2007 |
Flaig TW, Su LJ, Harrison G, Agarwal R, Glodé LM. Silibinin synergizes with mitoxantrone to inhibit cell growth and induce apoptosis in human prostate cancer cells. International Journal of Cancer. 120: 2028-33. PMID 17230508 DOI: 10.1002/Ijc.22465 |
0.427 |
|
| 2007 |
Kaur M, Agarwal R. Silymarin and epithelial cancer chemoprevention: How close we are to bedside? Toxicology and Applied Pharmacology. 224: 350-359. PMID 17184801 DOI: 10.1016/J.Taap.2006.11.011 |
0.409 |
|
| 2007 |
Agarwal C, Tyagi A, Agarwal R. Gallic acid causes inactivating phosphorylation of cdc25A/cdc25C-cdc2 via ATM-Chk2 activation, leading to cell cycle arrest, and induces apoptosis in human prostate carcinoma DU145 cells. Molecular Cancer Therapeutics. 5: 3294-302. PMID 17172433 DOI: 10.1158/1535-7163.Mct-06-0483 |
0.419 |
|
| 2007 |
Flaig TW, Gustafson DL, Su LJ, Zirrolli JA, Crighton F, Harrison GS, Pierson AS, Agarwal R, Glodé LM. A phase I and pharmacokinetic study of silybin-phytosome in prostate cancer patients. Investigational New Drugs. 25: 139-46. PMID 17077998 DOI: 10.1007/S10637-006-9019-2 |
0.328 |
|
| 2006 |
Agarwal R, Agarwal C, Ichikawa H, Singh RP, Aggarwal BB. Anticancer potential of silymarin: from bench to bed side. Anticancer Research. 26: 4457-98. PMID 17201169 |
0.321 |
|
| 2006 |
Kaur M, Singh RP, Gu M, Agarwal R, Agarwal C. Grape seed extract inhibits in vitro and in vivo growth of human colorectal carcinoma cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 6194-202. PMID 17062697 DOI: 10.1158/1078-0432.Ccr-06-1465 |
0.413 |
|
| 2006 |
Singh RP, Agarwal R. Mechanisms of action of novel agents for prostate cancer chemoprevention. Endocrine-Related Cancer. 13: 751-78. PMID 16954429 DOI: 10.1677/Erc.1.01126 |
0.413 |
|
| 2006 |
Gu M, Singh RP, Dhanalakshmi S, Mohan S, Agarwal R. Differential effect of silibinin on E2F transcription factors and associated biological events in chronically UVB-exposed skin versus tumors in SKH-1 hairless mice. Molecular Cancer Therapeutics. 5: 2121-9. PMID 16928834 DOI: 10.1158/1535-7163.Mct-06-0052 |
0.462 |
|
| 2006 |
Singh RP, Deep G, Chittezhath M, Kaur M, Dwyer-Nield LD, Malkinson AM, Agarwal R. Effect of silibinin on the growth and progression of primary lung tumors in mice. Journal of the National Cancer Institute. 98: 846-55. PMID 16788158 DOI: 10.1093/Jnci/Djj231 |
0.331 |
|
| 2006 |
Tyagi A, Singh RP, Agarwal C, Agarwal R. Silibinin activates p53-caspase 2 pathway and causes caspase-mediated cleavage of Cip1/p21 in apoptosis induction in bladder transitional-cell papilloma RT4 cells: evidence for a regulatory loop between p53 and caspase 2. Carcinogenesis. 27: 2269-80. PMID 16777994 DOI: 10.1093/Carcin/Bgl098 |
0.366 |
|
| 2006 |
Kaur M, Agarwal R, Agarwal C. Grape seed extract induces anoikis and caspase-mediated apoptosis in human prostate carcinoma LNCaP cells: possible role of ataxia telangiectasia mutated-p53 activation. Molecular Cancer Therapeutics. 5: 1265-74. PMID 16731759 DOI: 10.1158/1535-7163.Mct-06-0014 |
0.464 |
|
| 2006 |
Singh RP, Dhanalakshmi S, Mohan S, Agarwal C, Agarwal R. Silibinin inhibits UVB- and epidermal growth factor-induced mitogenic and cell survival signaling involving activator protein-1 and nuclear factor-kappaB in mouse epidermal JB6 cells. Molecular Cancer Therapeutics. 5: 1145-53. PMID 16731746 DOI: 10.1158/1535-7163.Mct-05-0478 |
0.406 |
|
| 2006 |
Dwivedi C, Valluri HB, Guan X, Agarwal R. Chemopreventive effects of alpha-santalol on ultraviolet B radiation-induced skin tumor development in SKH-1 hairless mice. Carcinogenesis. 27: 1917-22. PMID 16679309 DOI: 10.1093/Carcin/Bgl058 |
0.35 |
|
| 2006 |
Singh RP, Agarwal R. Prostate cancer chemoprevention by silibinin: bench to bedside. Molecular Carcinogenesis. 45: 436-42. PMID 16637061 DOI: 10.1002/Mc.20223 |
0.403 |
|
| 2006 |
Singh RP, Agarwal R. Natural flavonoids targeting deregulated cell cycle progression in cancer cells. Current Drug Targets. 7: 345-54. PMID 16515531 DOI: 10.2174/138945006776055004 |
0.451 |
|
| 2006 |
Veluri R, Singh RP, Liu Z, Thompson JA, Agarwal R, Agarwal C. Fractionation of grape seed extract and identification of gallic acid as one of the major active constituents causing growth inhibition and apoptotic death of DU145 human prostate carcinoma cells. Carcinogenesis. 27: 1445-53. PMID 16474170 DOI: 10.1093/Carcin/Bgi347 |
0.356 |
|
| 2006 |
Deep G, Singh RP, Agarwal C, Kroll DJ, Agarwal R. Silymarin and silibinin cause G1 and G2–M cell cycle arrest via distinct circuitries in human prostate cancer PC3 cells: a comparison of flavanone silibinin with flavanolignan mixture silymarin Oncogene. 25: 1053-1069. PMID 16205633 DOI: 10.1038/Sj.Onc.1209146 |
0.4 |
|
| 2005 |
Singh RP, Agarwal R. Mechanisms and preclinical efficacy of silibinin in preventing skin cancer. European Journal of Cancer (Oxford, England : 1990). 41: 1969-79. PMID 16084079 DOI: 10.1016/J.Ejca.2005.03.033 |
0.444 |
|
| 2005 |
Singh RP, Agarwal R. Prostate cancer and inositol hexaphosphate: efficacy and mechanisms. Anticancer Research. 25: 2891-903. PMID 16080543 |
0.321 |
|
| 2005 |
Tyagi A, Singh RP, Agarwal C, Siriwardana S, Sclafani RA, Agarwal R. Resveratrol causes Cdc2-tyr15 phosphorylation via ATM/ATR-Chk1/2-Cdc25C pathway as a central mechanism for S phase arrest in human ovarian carcinoma Ovcar-3 cells. Carcinogenesis. 26: 1978-87. PMID 15975956 DOI: 10.1093/Carcin/Bgi165 |
0.39 |
|
| 2005 |
Davis-Searles PR, Nakanishi Y, Kim NC, Graf TN, Oberlies NH, Wani MC, Wall ME, Agarwal R, Kroll DJ. Milk thistle and prostate cancer: Differential effects of pure flavonolignans from Silybum marianum on antiproliferative end points in human prostate carcinoma cells Cancer Research. 65: 4448-4457. PMID 15899838 DOI: 10.1158/0008-5472.Can-04-4662 |
0.356 |
|
| 2005 |
Gu M, Dhanalakshmi S, Singh RP, Agarwal R. Dietary feeding of silibinin prevents early biomarkers of UVB radiation-induced carcinogenesis in SKH-1 hairless mouse epidermis. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 14: 1344-9. PMID 15894701 DOI: 10.1158/1055-9965.Epi-04-0664 |
0.47 |
|
| 2005 |
Gu M, Dhanalakshmi S, Mohan S, Singh RP, Agarwal R. Silibinin inhibits ultraviolet B radiation-induced mitogenic and survival signaling, and associated biological responses in SKH-1 mouse skin. Carcinogenesis. 26: 1404-13. PMID 15831527 DOI: 10.1093/Carcin/Bgi096 |
0.434 |
|
| 2005 |
Dhanalakshmi S, Agarwal C, Singh RP, Agarwal R. Silibinin up-regulates DNA-protein kinase-dependent p53 activation to enhance UVB-induced apoptosis in mouse epithelial JB6 cells. The Journal of Biological Chemistry. 280: 20375-83. PMID 15792956 DOI: 10.1074/Jbc.M414640200 |
0.397 |
|
| 2005 |
Yim D, Singh RP, Agarwal C, Lee S, Chi H, Agarwal R. A novel anticancer agent, decursin, induces G1 arrest and apoptosis in human prostate carcinoma cells. Cancer Research. 65: 1035-44. PMID 15705905 |
0.31 |
|
| 2005 |
Singh RP, Agrawal P, Yim D, Agarwal C, Agarwal R. Acacetin inhibits cell growth and cell cycle progression, and induces apoptosis in human prostate cancer cells: Structure-activity relationship with linarin and linarin acetate Carcinogenesis. 26: 845-854. PMID 15637089 DOI: 10.1093/Carcin/Bgi014 |
0.448 |
|
| 2005 |
Singh RP, Dhanalakshmi S, Agarwal C, Agarwal R. Silibinin strongly inhibits growth and survival of human endothelial cells via cell cycle arrest and downregulation of survivin, Akt and NF-kappaB: implications for angioprevention and antiangiogenic therapy. Oncogene. 24: 1188-202. PMID 15558015 DOI: 10.1038/Sj.Onc.1208276 |
0.437 |
|
| 2005 |
Kaur M, Agarwal C, Singh RP, Guan X, Dwivedi C, Agarwal R. Skin cancer chemopreventive agent, {alpha}-santalol, induces apoptotic death of human epidermoid carcinoma A431 cells via caspase activation together with dissipation of mitochondrial membrane potential and cytochrome c release. Carcinogenesis. 26: 369-80. PMID 15528219 DOI: 10.1093/Carcin/Bgh325 |
0.429 |
|
| 2005 |
Flaig T, Agarwal R, Su L, Harrison GS, Gustafson DL, Glode LM. A phase I study of silibinin in hormone refractory prostate cancer Journal of Clinical Oncology. 23: 4698-4698. DOI: 10.1200/Jco.2005.23.16_Suppl.4698 |
0.31 |
|
| 2004 |
Singh RP, Mallikarjuna GU, Sharma G, Dhanalakshmi S, Tyagi AK, Chan DC, Agarwal C, Agarwal R. Oral silibinin inhibits lung tumor growth in athymic nude mice and forms a novel chemocombination with doxorubicin targeting nuclear factor kappaB-mediated inducible chemoresistance. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 8641-7. PMID 15623648 DOI: 10.1158/1078-0432.Ccr-04-1435 |
0.446 |
|
| 2004 |
Agarwal C, Dhanalakshmi S, Singh RP, Agarwal R. Inositol hexaphosphate inhibits growth and induces G1 arrest and apoptotic death of androgen-dependent human prostate carcinoma LNCaP cells. Neoplasia (New York, N.Y.). 6: 646-59. PMID 15548374 DOI: 10.1593/Neo.04232 |
0.454 |
|
| 2004 |
Singh RP, Agarwal R. A cancer chemopreventive agent silibinin, targets mitogenic and survival signaling in prostate cancer. Mutation Research. 555: 21-32. PMID 15476849 DOI: 10.1016/J.Mrfmmm.2004.05.017 |
0.432 |
|
| 2004 |
Mallikarjuna G, Dhanalakshmi S, Singh RP, Agarwal C, Agarwal R. Silibinin protects against photocarcinogenesis via modulation of cell cycle regulators, mitogen-activated protein kinases, and Akt signaling. Cancer Research. 64: 6349-56. PMID 15342425 DOI: 10.1158/0008-5472.Can-04-1632 |
0.413 |
|
| 2004 |
Mohan S, Dhanalakshmi S, Mallikarjuna GU, Singh RP, Agarwal R. Silibinin modulates UVB-induced apoptosis via mitochondrial proteins, caspases activation, and mitogen-activated protein kinase signaling in human epidermoid carcinoma A431 cells. Biochemical and Biophysical Research Communications. 320: 183-9. PMID 15207719 DOI: 10.1016/J.Bbrc.2004.05.153 |
0.427 |
|
| 2004 |
Tyagi A, Agarwal C, Harrison G, Glode LM, Agarwal R. Silibinin causes cell cycle arrest and apoptosis in human bladder transitional cell carcinoma cells by regulating CDKI-CDK-cyclin cascade, and caspase 3 and PARP cleavages. Carcinogenesis. 25: 1711-20. PMID 15117815 DOI: 10.1093/Carcin/Bgh180 |
0.463 |
|
| 2004 |
Sharma G, Tyagi AK, Singh RP, Chan DC, Agarwal R. Synergistic anti-cancer effects of grape seed extract and conventional cytotoxic agent doxorubicin against human breast carcinoma cells. Breast Cancer Research and Treatment. 85: 1-12. PMID 15039593 DOI: 10.1023/B:Brea.0000020991.55659.59 |
0.45 |
|
| 2004 |
Dhanalakshmi S, Mallikarjuna GU, Singh RP, Agarwal R. Silibinin prevents ultraviolet radiation-caused skin damages in SKH-1 hairless mice via a decrease in thymine dimer positive cells and an up-regulation of p53-p21/Cip1 in epidermis. Carcinogenesis. 25: 1459-65. PMID 15033902 DOI: 10.1093/Carcin/Bgh152 |
0.448 |
|
| 2004 |
Singh RP, Agarwal R. Prostate cancer prevention by silibinin. Current Cancer Drug Targets. 4: 1-11. PMID 14965263 DOI: 10.2174/1568009043481605 |
0.447 |
|
| 2004 |
Singh RP, Sharma G, Mallikarjuna GU, Dhanalakshmi S, Agarwal C, Agarwal R. In vivo suppression of hormone-refractory prostate cancer growth by inositol hexaphosphate: induction of insulin-like growth factor binding protein-3 and inhibition of vascular endothelial growth factor. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 244-50. PMID 14734476 DOI: 10.1158/1078-0432.Ccr-1080-3 |
0.316 |
|
| 2004 |
Tyagi AK, Agarwal C, Chan DC, Agarwal R. Synergistic anti-cancer effects of silibinin with conventional cytotoxic agents doxorubicin, cisplatin and carboplatin against human breast carcinoma MCF-7 and MDA-MB468 cells. Oncology Reports. 11: 493-9. PMID 14719089 |
0.331 |
|
| 2004 |
Singh RP, Tyagi AK, Dhanalakshmi S, Agarwal R, Agarwal C. Grape seed extract inhibits advanced human prostate tumor growth and angiogenesis and upregulates insulin-like growth factor binding protein-3. International Journal of Cancer. 108: 733-40. PMID 14696100 DOI: 10.1002/Ijc.11620 |
0.416 |
|
| 2004 |
Tyagi AK, Agarwal C, Singh RP, Shroyer KR, Glode LM, Agarwal R. Silibinin down-regulates survivin protein and mRNA expression and causes caspases activation and apoptosis in human bladder transitional-cell papilloma RT4 cells. Biochemical and Biophysical Research Communications. 312: 1178-84. PMID 14651997 DOI: 10.1016/J.Bbrc.2003.11.038 |
0.478 |
|
| 2004 |
Sharma G, Singh RP, Agarwal R. Growth inhibitory and apoptotic effects of inositol hexaphosphate in transgenic adenocarcinoma of mouse prostate (TRAMP-C1) cells. International Journal of Oncology. 23: 1413-8. PMID 14532984 |
0.359 |
|
| 2004 |
Dhanalakshmi S, Agarwal R, Agarwal C. Inhibition of NF-kappaB pathway in grape seed extract-induced apoptotic death of human prostate carcinoma DU145 cells. International Journal of Oncology. 23: 721-7. PMID 12888909 |
0.343 |
|
| 2004 |
Agarwal C, Singh RP, Dhanalakshmi S, Agarwal R. Anti-angiogenic efficacy of grape seed extract in endothelial cells. Oncology Reports. 11: 681-685. DOI: 10.3892/Or.11.3.681 |
0.408 |
|
| 2004 |
Tyagi AK, Agarwal C, Chan DCF, Agarwal R. Synergistic Anti-Cancer Effects Of Silibinin With Conventional Cytotoxic Agents Doxorubicin, Cisplatin And Carboplatin Against Human Breast Carcinoma Mcf-7 And Mda-Mb468 Cells Oncology Reports. 11: 493-499. DOI: 10.3892/Or.11.2.493 |
0.442 |
|
| 2003 |
Agarwal C, Singh RP, Dhanalakshmi S, Tyagi AK, Tecklenburg M, Sclafani RA, Agarwal R. Silibinin upregulates the expression of cyclin-dependent kinase inhibitors and causes cell cycle arrest and apoptosis in human colon carcinoma HT-29 cells. Oncogene. 22: 8271-82. PMID 14614451 DOI: 10.1038/Sj.Onc.1207158 |
0.46 |
|
| 2003 |
Qi L, Singh RP, Lu Y, Agarwal R, Harrison GS, Franzusoff A, Glode LM. Epidermal growth factor receptor mediates silibinin-induced cytotoxicity in a rat glioma cell line. Cancer Biology & Therapy. 2: 526-31. PMID 14614320 DOI: 10.4161/Cbt.2.5.452 |
0.394 |
|
| 2003 |
Dhanalakshmi S, Mallikarjuna GU, Singh RP, Agarwal R. Dual efficacy of silibinin in protecting or enhancing ultraviolet B radiation-caused apoptosis in HaCaT human immortalized keratinocytes. Carcinogenesis. 25: 99-106. PMID 14555614 DOI: 10.1093/Carcin/Bgg188 |
0.435 |
|
| 2003 |
Dhanalakshmi S, Agarwal P, Glode LM, Agarwal R. Silibinin sensitizes human prostate carcinoma DU145 cells to cisplatin- and carboplatin-induced growth inhibition and apoptotic death. International Journal of Cancer. 106: 699-705. PMID 12866029 DOI: 10.1002/Ijc.11299 |
0.439 |
|
| 2003 |
Singh RP, Agarwal R. Tumor angiogenesis: a potential target in cancer control by phytochemicals. Current Cancer Drug Targets. 3: 205-17. PMID 12769689 DOI: 10.2174/1568009033481985 |
0.426 |
|
| 2003 |
Singh RP, Agarwal C, Agarwal R. Inositol hexaphosphate inhibits growth, and induces G1 arrest and apoptotic death of prostate carcinoma DU145 cells: modulation of CDKI-CDK-cyclin and pRb-related protein-E2F complexes. Carcinogenesis. 24: 555-63. PMID 12663518 DOI: 10.1093/Carcin/24.3.555 |
0.443 |
|
| 2003 |
Tyagi A, Agarwal R, Agarwal C. Grape seed extract inhibits EGF-induced and constitutively active mitogenic signaling but activates JNK in human prostate carcinoma DU145 cells: possible role in antiproliferation and apoptosis. Oncogene. 22: 1302-16. PMID 12618755 DOI: 10.1038/Sj.Onc.1206265 |
0.44 |
|
| 2003 |
Tyagi A, Agarwal C, Agarwal R. Inhibition of retinoblastoma protein (Rb) phosphorylation at serine sites and an increase in Rb-E2F complex formation by silibinin in androgen-dependent human prostate carcinoma LNCaP cells: role in prostate cancer prevention. Molecular Cancer Therapeutics. 1: 525-32. PMID 12479270 |
0.302 |
|
| 2003 |
Tyagi A, Agarwal C, Agarwal R. The cancer preventive flavonoid silibinin causes hypophosphorylation of Rb/p107 and Rb2/p130 via modulation of cell cycle regulators in human prostate carcinoma DU145 cells. Cell Cycle (Georgetown, Tex.). 1: 137-42. PMID 12429923 |
0.351 |
|
| 2003 |
Tyagi AK, Singh RP, Agarwal C, Chan DC, Agarwal R. Silibinin strongly synergizes human prostate carcinoma DU145 cells to doxorubicin-induced growth Inhibition, G2-M arrest, and apoptosis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 8: 3512-9. PMID 12429642 |
0.305 |
|
| 2003 |
Singh RP, Agarwal R. Flavonoid antioxidant silymarin and skin cancer. Antioxidants & Redox Signaling. 4: 655-63. PMID 12230878 DOI: 10.1089/15230860260220166 |
0.467 |
|
| 2003 |
Sharma G, Singh RP, Agarwal R. Growth inhibitory and apoptotic effects of inositol hexaphosphate in transgenic adenocarcinoma of mouse prostate (TRAMP-C1) cells. International Journal of Oncology. 23: 1413-1418. DOI: 10.3892/Ijo.23.5.1413 |
0.465 |
|
| 2003 |
Dhanalakshmi S, Agarwal R, Agarwal C. Inhibition of NF-κB pathway in grape seed extract-induced apoptotic death of human prostate carcinoma DU145 cells International Journal of Oncology. 23: 721-727. DOI: 10.3892/Ijo.23.3.721 |
0.452 |
|
| 2002 |
Singh RP, Dhanalakshmi S, Agarwal R. Phytochemicals as cell cycle modulators--a less toxic approach in halting human cancers. Cell Cycle (Georgetown, Tex.). 1: 156-61. PMID 12429925 |
0.363 |
|
| 2002 |
Agarwal C, Singh RP, Agarwal R. Grape seed extract induces apoptotic death of human prostate carcinoma DU145 cells via caspases activation accompanied by dissipation of mitochondrial membrane potential and cytochrome c release. Carcinogenesis. 23: 1869-76. PMID 12419835 DOI: 10.1093/Carcin/23.11.1869 |
0.416 |
|
| 2002 |
Tyagi A, Bhatia N, Condon MS, Bosland MC, Agarwal C, Agarwal R. Antiproliferative and apoptotic effects of silibinin in rat prostate cancer cells Prostate. 53: 211-217. PMID 12386921 DOI: 10.1002/Pros.10146 |
0.449 |
|
| 2002 |
Jiang W, Zhu Z, Bhatia N, Agarwal R, Thompson HJ. Mechanisms of energy restriction: effects of corticosterone on cell growth, cell cycle machinery, and apoptosis. Cancer Research. 62: 5280-7. PMID 12234997 |
0.33 |
|
| 2002 |
Singh RP, Dhanalakshmi S, Tyagi AK, Chan DC, Agarwal C, Agarwal R. Dietary feeding of silibinin inhibits advance human prostate carcinoma growth in athymic nude mice and increases plasma insulin-like growth factor-binding protein-3 levels. Cancer Research. 62: 3063-9. PMID 12036915 |
0.303 |
|
| 2002 |
Dhanalakshmi S, Singh RP, Agarwal C, Agarwal R. Silibinin inhibits constitutive and TNFα-induced activation of NF-κB and sensitizes human prostate carcinoma DU145 cells to TNFα-induced apoptosis Oncogene. 21: 1759-1767. PMID 11896607 DOI: 10.1038/Sj.Onc.1205240 |
0.451 |
|
| 2002 |
Singh RP, Tyagi AK, Zhao J, Agarwal R. Silymarin inhibits growth and causes regression of established skin tumors in SENCAR mice via modulation of mitogen-activated protein kinases and induction of apoptosis. Carcinogenesis. 23: 499-510. PMID 11895866 DOI: 10.1093/Carcin/23.3.499 |
0.465 |
|
| 2002 |
Bhatia N, Agarwal C, Agarwal R. Differential responses of skin cancer-chemopreventive agents silibinin, quercetin, and epigallocatechin 3-gallate on mitogenic signaling and cell cycle regulators in human epidermoid carcinoma A431 cells. Nutrition and Cancer. 39: 292-9. PMID 11759294 DOI: 10.1207/S15327914Nc392_20 |
0.469 |
|
| 2002 |
Singh RP, Dhanalakshmi S, Agarwal R. Phytochemicals as Cell Cycle Modulators A Less Toxic Approach in Halting Human Cancers Cell Cycle. 1: 155-160. DOI: 10.4161/Cc.1.3.117 |
0.471 |
|
| 2001 |
Sharma Y, Agarwal C, Singh AK, Agarwal R. Inhibitory effect of silibinin on ligand binding to erbB1 and associated mitogenic signaling, growth, and DNA synthesis in advanced human prostate carcinoma cells. Molecular Carcinogenesis. 30: 224-36. PMID 11346885 DOI: 10.1002/Mc.1032 |
0.435 |
|
| 2001 |
Bhatia N, Agarwal R. Detrimental effect of cancer preventive phytochemicals silymarin, genistein and epigallocatechin 3-gallate on epigenetic events in human prostate carcinoma DU145 cells. The Prostate. 46: 98-107. PMID 11170137 DOI: 10.1002/1097-0045(20010201)46:2<98::Aid-Pros1013>3.0.Co;2-K |
0.438 |
|
| 2001 |
Zi X, Singh RP, Agarwal R. Impairment of erbB1 receptor and fluid-phase endocytosis and associated mitogenic signaling by inositol hexaphosphate in human prostate carcinoma DU145 cells. Carcinogenesis. 21: 2225-35. PMID 11133812 DOI: 10.1093/Carcin/21.12.2225 |
0.391 |
|
| 2000 |
Agarwal R. Cell signaling and regulators of cell cycle as molecular targets for prostate cancer prevention by dietary agents. Biochemical Pharmacology. 60: 1051-1059. PMID 11007941 DOI: 10.1016/S0006-2952(00)00385-3 |
0.475 |
|
| 2000 |
Jiang C, Agarwal R, Lü J. Anti-angiogenic potential of a cancer chemopreventive flavonoid antioxidant, silymarin: inhibition of key attributes of vascular endothelial cells and angiogenic cytokine secretion by cancer epithelial cells. Biochemical and Biophysical Research Communications. 276: 371-8. PMID 11006131 DOI: 10.1006/Bbrc.2000.3474 |
0.456 |
|
| 2000 |
Agarwal C, Sharma Y, Agarwal R. Anticarcinogenic effect of a polyphenolic fraction isolated from grape seeds in human prostate carcinoma DU145 cells: modulation of mitogenic signaling and cell-cycle regulators and induction of G1 arrest and apoptosis. Molecular Carcinogenesis. 28: 129-38. PMID 10942529 DOI: 10.1002/1098-2744(200007)28:3<129::Aid-Mc1>3.0.Co;2-0 |
0.456 |
|
| 2000 |
Zhao J, Lahiri-Chatterjee M, Sharma Y, Agarwal R. Inhibitory effect of a flavonoid antioxidant silymarin on benzoyl peroxide-induced tumor promotion, oxidative stress and inflammatory responses in SENCAR mouse skin. Carcinogenesis. 21: 811-6. PMID 10753220 DOI: 10.1093/Carcin/21.4.811 |
0.414 |
|
| 2000 |
Bhatia N, Zhao J, Wolf DM, Agarwal R. Inhibition of human carcinoma cell growth and DNA synthesis by silibinin, an active constituent of milk thistle: comparison with silymarin. Cancer Letters. 147: 77-84. PMID 10660092 DOI: 10.1016/S0304-3835(99)00276-1 |
0.441 |
|
| 1999 |
Zhao J, Sharma Y, Agarwal R. Significant inhibition by the flavonoid antioxidant silymarin against 12-O-tetradecanoylphorbol 13-acetate-caused modulation of antioxidant and inflammatory enzymes, and cyclooxygenase 2 and interleukin-1alpha expression in SENCAR mouse epidermis: implications in the prevention of stage I tumor promotion. Molecular Carcinogenesis. 26: 321-33. PMID 10569809 DOI: 10.1002/(Sici)1098-2744(199912)26:4<321::Aid-Mc11>3.0.Co;2-9 |
0.462 |
|
| 1999 |
Zhao J, Agarwal R. Tissue distribution of silibinin, the major active constituent of silymarin, in mice and its association with enhancement of phase II enzymes: implications in cancer chemoprevention Carcinogenesis. 20: 2101-2108. PMID 10545412 DOI: 10.1093/Carcin/20.11.2101 |
0.394 |
|
| 1999 |
Zi X, Agarwal R. Modulation of mitogen-activated protein kinase activation and cell cycle regulators by the potent skin cancer preventive agent silymarin. Biochemical and Biophysical Research Communications. 263: 528-36. PMID 10491326 DOI: 10.1006/Bbrc.1999.1398 |
0.446 |
|
| 1999 |
Zhao J, Wang J, Chen Y, Agarwal R. Anti-tumor-promoting activity of a polyphenolic fraction isolated from grape seeds in the mouse skin two-stage initiation-promotion protocol and identification of procyanidin B5-3'-gallate as the most effective antioxidant constituent. Carcinogenesis. 20: 1737-1745. PMID 10469619 DOI: 10.1093/Carcin/20.9.1737 |
0.373 |
|
| 1999 |
Zi X, Agarwal R. Silibinin decreases prostate-specific antigen with cell growth inhibition via G1 arrest, leading to differentiation of prostate carcinoma cells: implications for prostate cancer intervention. Proceedings of the National Academy of Sciences of the United States of America. 96: 7490-5. PMID 10377442 DOI: 10.1073/Pnas.96.13.7490 |
0.42 |
|
| 1998 |
Ahmad N, Gali H, Javed S, Agarwal R. Skin cancer chemopreventive effects of a flavonoid antioxidant silymarin are mediated via impairment of receptor tyrosine kinase signaling and perturbation in cell cycle progression. Biochemical and Biophysical Research Communications. 247: 294-301. PMID 9642119 DOI: 10.1006/Bbrc.1998.8748 |
0.446 |
|
| 1998 |
Ahmad N, Feyes DK, Agarwal R, Mukhtar H. Photodynamic therapy results in induction of WAF1/CIP1/P21 leading to cell cycle arrest and apoptosis. Proceedings of the National Academy of Sciences of the United States of America. 95: 6977-82. PMID 9618524 DOI: 10.1073/Pnas.95.12.6977 |
0.38 |
|
| 1998 |
Ahmad N, Feyes DK, Nieminen AL, Agarwal R, Mukhtar H. Green tea constituent epigallocatechin-3-gallate and induction of apoptosis and cell cycle arrest in human carcinoma cells. Journal of the National Cancer Institute. 89: 1881-6. PMID 9414176 DOI: 10.1093/Jnci/89.24.1881 |
0.452 |
|
| 1997 |
Zi X, Mukhtar H, Agarwal R. Novel cancer chemopreventive effects of a flavonoid antioxidant silymarin: inhibition of mRNA expression of an endogenous tumor promoter TNF alpha. Biochemical and Biophysical Research Communications. 239: 334-9. PMID 9345320 DOI: 10.1006/Bbrc.1997.7375 |
0.364 |
|
| 1997 |
Srivastava SK, Hu X, Xia H, Zaren HA, Chatterjee ML, Agarwal R, Singh SV. Mechanism of differential efficacy of garlic organosulfides in preventing benzo(a)pyrene-induced cancer in mice. Cancer Letters. 118: 61-7. PMID 9310261 DOI: 10.1016/S0304-3835(97)00237-1 |
0.397 |
|
| 1997 |
Ahmad N, Srivastava RC, Agarwal R, Mukhtar H. Nitric oxide synthase and skin tumor promotion. Biochemical and Biophysical Research Communications. 232: 328-31. PMID 9125174 DOI: 10.1006/Bbrc.1997.6275 |
0.358 |
|
| 1997 |
Katiyar SK, Korman NJ, Mukhtar H, Agarwal R. Protective effects of silymarin against photocarcinogenesis in a mouse skin model. Journal of the National Cancer Institute. 89: 556-66. PMID 9106644 DOI: 10.1093/Jnci/89.8.556 |
0.398 |
|
| 1997 |
Katiyar SK, Mohan RR, Agarwal R, Mukhtar H. Protection against induction of mouse skin papillomas with low and high risk of conversion to malignancy by green tea polyphenols. Carcinogenesis. 18: 497-502. PMID 9067548 DOI: 10.1093/Carcin/18.3.497 |
0.344 |
|
| 1997 |
Chatterjee ML, Agarwal R, Mukhtar H. Ultraviolet B radiation-induced DNA lesions in mouse epidermis: an assessment using a novel 32P-postlabelling technique. Biochemical and Biophysical Research Communications. 229: 590-5. PMID 8954942 DOI: 10.1006/Bbrc.1996.1848 |
0.357 |
|
| 1997 |
Agarwal R, Mukhtar H. Cancer chemoprevention by polyphenols in green tea and artichoke. Advances in Experimental Medicine and Biology. 401: 35-50. PMID 8886125 DOI: 10.1007/978-1-4613-0399-2_4 |
0.41 |
|
| 1996 |
Agarwal R, Korman NJ, Mohan RR, Feyes DK, Jawed S, Zaim MT, Mukhtar H. Apoptosis is an early event during phthalocyanine photodynamic therapy-induced ablation of chemically induced squamous papillomas in mouse skin. Photochemistry and Photobiology. 63: 547-52. PMID 8934768 DOI: 10.1111/J.1751-1097.1996.Tb03082.X |
0.412 |
|
| 1996 |
Agarwal R, Mukhtar H. Chemoprevention of Photocarcinogenesis Photochemistry and Photobiology. 63: 440-444. PMID 8934760 DOI: 10.1111/J.1751-1097.1996.Tb03066.X |
0.341 |
|
| 1996 |
Singh SV, Mohan RR, Agarwal R, Benson PJ, Hu X, Rudy MA, Xia H, Katoh A, Srivastava SK, Mukhtar H, Gupta V, Zaren HA. Novel anti-carcinogenic activity of an organosulfide from garlic: inhibition of H-RAS oncogene transformed tumor growth in vivo by diallyl disulfide is associated with inhibition of p21H-ras processing. Biochemical and Biophysical Research Communications. 225: 660-5. PMID 8753815 DOI: 10.1006/Bbrc.1996.1226 |
0.325 |
|
| 1996 |
Khan SG, Dummer R, Siddiqui J, Bickers DR, Agarwal R, Mukhtar H. Farnesyltransferase activity and mRNA expression in human skin basal cell carcinomas. Biochemical and Biophysical Research Communications. 220: 795-801. PMID 8607844 DOI: 10.1006/Bbrc.1996.0483 |
0.345 |
|
| 1996 |
Katiyar SK, Elmets CA, Agarwal R, Mukhtar H. Protection against ultraviolet-B radiation-induced local and systemic suppression of contact hypersensitivity and edema responses in C3H/HeN mice by green tea polyphenols. Photochemistry and Photobiology. 62: 855-61. PMID 8570723 DOI: 10.1111/J.1751-1097.1995.Tb09147.X |
0.333 |
|
| 1995 |
Khan SG, Saxena R, Bickers DR, Mukhtar H, Agarwal R. Inhibition of ras p21 membrane localization and modulation of protein kinase C isozyme expression during regression of chemical carcinogen-induced murine skin tumors by lovastatin. Molecular Carcinogenesis. 12: 205-12. PMID 7727042 DOI: 10.1002/Mc.2940120405 |
0.311 |
|
| 1995 |
Katiyar SK, Rupp CO, Korman NJ, Agarwal R, Mukhtar H. Inhibition of 12-O-tetradecanoylphorbol-13-acetate and other skin tumor-promoter-caused induction of epidermal interleukin-1 alpha mRNA and protein expression in SENCAR mice by green tea polyphenols. The Journal of Investigative Dermatology. 105: 394-8. PMID 7665919 DOI: 10.1111/1523-1747.Ep12321030 |
0.343 |
|
| 1994 |
Mukhtar H, Katiyar SK, Agarwal R. Green tea and skin--anticarcinogenic effects. The Journal of Investigative Dermatology. 102: 3-7. PMID 8288907 DOI: 10.1111/1523-1747.Ep12371720 |
0.372 |
|
| 1994 |
Agarwal R, Katiyar SK, Khan SG, Mukhtar H. Protection against ultraviolet B radiation-induced effects in the skin of SKH-1 hairless mice by a polyphenolic fraction isolated from green tea. Photochemistry and Photobiology. 58: 695-700. PMID 8284325 DOI: 10.1111/J.1751-1097.1993.Tb04954.X |
0.356 |
|
| 1994 |
Katiyar SK, Agarwal R, Mukhtar H. Inhibition of both stage I and stage II skin tumor promotion in SENCAR mice by a polyphenolic fraction isolated from green tea: inhibition depends on the duration of polyphenol treatment. Carcinogenesis. 14: 2641-3. PMID 8269639 DOI: 10.1093/Carcin/14.12.2641 |
0.336 |
|
| 1994 |
Katiyar SK, Agarwal R, Mukhtar H. Inhibition of spontaneous and photo-enhanced lipid peroxidation in mouse epidermal microsomes by epicatechin derivatives from green tea. Cancer Letters. 79: 61-6. PMID 8187054 DOI: 10.1016/0304-3835(94)90063-9 |
0.388 |
|
| 1994 |
Khan SG, Bickers DR, Mukhtar H, Agarwal R. Ras p21 farnesylation in ultraviolet B radiation-induced tumors in the skin of SKH-1 hairless mice. The Journal of Investigative Dermatology. 102: 754-8. PMID 8176259 DOI: 10.1111/1523-1747.Ep12377020 |
0.325 |
|
| 1994 |
Mukhtar H, Katiyar SK, Agarwal R. Cancer chemoprevention by green tea components. Advances in Experimental Medicine and Biology. 354: 123-34. PMID 8067281 DOI: 10.1007/978-1-4899-0939-8_9 |
0.409 |
|
| 1994 |
Agarwal R, Katiyar SK, Lundgren DW, Mukhtar H. Inhibitory effect of silymarin, an anti-hepatotoxic flavonoid, on 12-O-tetradecanoylphorbol-13-acetate-induced epidermal ornithine decarboxylase activity and mRNA in SENCAR mice. Carcinogenesis. 15: 1099-103. PMID 8020140 DOI: 10.1093/Carcin/15.6.1099 |
0.406 |
|
| 1994 |
Jugert FK, Agarwal R, Kuhn A, Bickers DR, Merk HF, Mukhtar H. Multiple cytochrome P450 isozymes in murine skin: induction of P450 1A, 2B, 2E, and 3A by dexamethasone. The Journal of Investigative Dermatology. 102: 970-5. PMID 8006463 DOI: 10.1111/1523-1747.Ep12384210 |
0.33 |
|
| 1994 |
Agarwal R, Jugert FK, Khan SG, Bickers DR, Merk HF, Mukhtar H. Evidence for multiple inducible cytochrome P450 isozymes in SENCAR mouse skin by pyridine. Biochemical and Biophysical Research Communications. 199: 1400-6. PMID 7511897 DOI: 10.1006/Bbrc.1994.1386 |
0.33 |
|
| 1993 |
Katiyar SK, Agarwal R, Zaim MT, Mukhtar H. Protection against N-nitrosodiethylamine and benzo[a]pyrene-induced forestomach and lung tumorigenesis in A/J mice by green tea. Carcinogenesis. 14: 849-55. PMID 8504476 DOI: 10.1093/Carcin/14.5.849 |
0.389 |
|
| 1993 |
Katiyar SK, Agarwal R, Ekker S, Wood GS, Mukhtar H. Protection against 12-O-tetradecanoylphorbol-13-acetate-caused inflammation in SENCAR mouse ear skin by polyphenolic fraction isolated from green tea. Carcinogenesis. 14: 361-5. PMID 8453711 DOI: 10.1093/Carcin/14.3.361 |
0.415 |
|
| 1993 |
Zaidi SI, Agarwal R, Eichler G, Rihter BD, Kenney ME, Mukhtar H. Photodynamic effects of new silicon phthalocyanines: in vitro studies utilizing rat hepatic microsomes and human erythrocyte ghosts as model membrane sources Photochemistry and Photobiology. 58: 204-210. PMID 8415911 DOI: 10.1111/J.1751-1097.1993.Tb09550.X |
0.314 |
|
| 1993 |
Agarwal R, Khan SG, Athar M, Zaidi SI, Bickers DR, Mukhtar H. ras protein p21 processing enzyme farnesyltransferase in chemical carcinogen-induced murine skin tumors. Molecular Carcinogenesis. 8: 290-8. PMID 8280377 DOI: 10.1002/Mc.2940080412 |
0.338 |
|
| 1993 |
Katiyar SK, Agarwal R, Mukhtar H. Protective effects of green tea polyphenols administered by oral intubation against chemical carcinogen-induced forestomach and pulmonary neoplasia in A/J mice. Cancer Letters. 73: 167-72. PMID 8221629 DOI: 10.1016/0304-3835(93)90260-G |
0.389 |
|
| 1993 |
Agarwal R, Khan SG, Mukhtar H. Ras p21 farnesylation in ultraviolet radiation-induced tumors in murine skin Journal of Dermatological Science. 6: 8. DOI: 10.1016/0923-1811(93)90812-4 |
0.3 |
|
| 1993 |
Mukhtar H, Katiyar SK, Agarwal R. Protection against tumor promoter-induced inflammation in murine skin by green tea polyphenols Journal of Dermatological Science. 6: 8. DOI: 10.1016/0923-1811(93)90811-3 |
0.351 |
|
| 1992 |
Athar M, Agarwal R, Wang ZY, Lloyd JR, Bickers DR, Mukhtar H. All-trans retinoic acid protects against conversion of chemically induced and ultraviolet B radiation-induced skin papillomas to carcinomas. Carcinogenesis. 12: 2325-9. PMID 1747935 DOI: 10.1093/Carcin/12.12.2325 |
0.402 |
|
| 1992 |
Agarwal R, Zaidi SI, Athar M, Bickers DR, Mukhtar H. Photodynamic effects of chloroaluminum phthalocyanine tetrasulfonate are mediated by singlet oxygen: in vivo and in vitro studies utilizing hepatic microsomes as a model membrane source. Archives of Biochemistry and Biophysics. 294: 30-7. PMID 1550355 DOI: 10.1016/0003-9861(92)90132-G |
0.318 |
|
| 1992 |
Agarwal R, Athar M, Elmets CA, Bickers DR, Mukhtar H. Photodynamic therapy of chemically- and ultraviolet B radiation-induced murine skin papillomas by chloroaluminum phthalocyanine tetrasulfonate. Photochemistry and Photobiology. 56: 43-50. PMID 1508981 DOI: 10.1111/J.1751-1097.1992.Tb09600.X |
0.358 |
|
| 1992 |
Katiyar SK, Agarwal R, Wang ZY, Bhatia AK, Mukhtar H. (-)-Epigallocatechin-3-gallate in Camellia sinensis leaves from Himalayan region of Sikkim: inhibitory effects against biochemical events and tumor initiation in Sencar mouse skin. Nutrition and Cancer. 18: 73-83. PMID 1408948 DOI: 10.1080/01635589209514207 |
0.413 |
|
| 1991 |
Agarwal R, Athar M, Bickers DR, Mukhtar H. Evidence for the involvement of singlet oxygen in the photodestruction by chloroaluminum phthalocyanine tetrasulfonate. Biochemical and Biophysical Research Communications. 173: 34-41. PMID 2256924 DOI: 10.1016/S0006-291X(05)81017-4 |
0.317 |
|
| 1991 |
Agarwal R, Athar M, Urban SA, Bickers DR, Mukhtar H. Involvement of singlet oxygen in chloroaluminum phthalocyanine tetrasulfonate-mediated photoenhancement of lipid peroxidation in rat epidermal microsomes. Cancer Letters. 56: 125-9. PMID 1998941 DOI: 10.1016/0304-3835(91)90086-W |
0.31 |
|
| 1991 |
Agarwal R, Wang ZY, Mukhtar H. Inhibition of mouse skin tumor-initiating activity of DMBA by chronic oral feeding of glycyrrhizin in drinking water. Nutrition and Cancer. 15: 187-93. PMID 1907733 DOI: 10.1080/01635589109514126 |
0.399 |
|
| 1991 |
Wang ZY, Agarwal R, Bickers DR, Mukhtar H. Protection against ultraviolet B radiation-induced photocarcinogenesis in hairless mice by green tea polyphenols. Carcinogenesis. 12: 1527-30. PMID 1860173 DOI: 10.1093/Carcin/12.8.1527 |
0.384 |
|
| 1991 |
Wang ZY, Agarwal R, Zhou ZC, Bickers DR, Mukhtar H. Antimutagenic and antitumorigenic activities of nordihydroguaiaretic acid. Mutation Research. 261: 153-62. PMID 1719406 DOI: 10.1016/0165-1218(91)90062-Q |
0.404 |
|
| 1987 |
Mehrotra NK, Kumar S, Agarwal R, Antony M. Jute batching oil: a tumor promoter on mouse skin. Environmental Research. 42: 12-23. PMID 3803329 DOI: 10.1016/S0013-9351(87)80003-8 |
0.307 |
|
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