| Year |
Citation |
Score |
| 2022 |
Trieu KG, Tsai SY, Eberl M, Ju V, Ford NC, Doane OJ, Peterson JK, Veniaminova NA, Grachtchouk M, Harms PW, Swartling FJ, Dlugosz AA, Wong SY. Basal cell carcinomas acquire secondary mutations to overcome dormancy and progress from microscopic to macroscopic disease. Cell Reports. 39: 110779. PMID 35508126 DOI: 10.1016/j.celrep.2022.110779 |
0.341 |
|
| 2022 |
Verhaegen ME, Harms PW, Van Goor JJ, Arche J, Patrick MT, Wilbert D, Zabawa H, Grachtchouk M, Liu CJ, Hu K, Kelly MC, Chen P, Saunders TL, Weidinger S, Syu LJ, ... ... Dlugosz AA, et al. Direct cellular reprogramming enables development of viral T antigen-driven Merkel cell carcinoma in mice. The Journal of Clinical Investigation. PMID 35143422 DOI: 10.1172/JCI152069 |
0.421 |
|
| 2022 |
Kumari A, Li L, Ermilov AN, Franks NE, Dlugosz AA, Allen BL, Mistretta CM. Hedgehog (HH) pathway endogenous antagonist HHIP: unique lingual expression in filiform papillae during homeostasis and ectopic in fungiform papillae during HH signaling inhibition. Developmental Dynamics : An Official Publication of the American Association of Anatomists. PMID 35048440 DOI: 10.1002/dvdy.456 |
0.348 |
|
| 2021 |
Grachtchouk M, Liu J, Hutchin ME, Harms PW, Thomas D, Wei L, Wang A, Cummings D, Lowe L, Garlick J, Sciubba J, Chinnaiyan AM, Verhaegen ME, Dlugosz AA. Constitutive Hedgehog/GLI2 signaling drives extracutaneous basaloid squamous cell carcinoma development and bone remodeling. Carcinogenesis. PMID 34117865 DOI: 10.1093/carcin/bgab050 |
0.409 |
|
| 2021 |
Steele NG, Biffi G, Kemp SB, Zhang Y, Drouillard D, Syu LJ, Hao Y, Oni TE, Brosnan E, Elyada E, Doshi A, Hansma C, Espinoza C, Abbas A, The S, ... ... Dlugosz AA, et al. Inhibition of Hedgehog signaling alters fibroblast composition in pancreatic cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 33495315 DOI: 10.1158/1078-0432.CCR-20-3715 |
0.373 |
|
| 2020 |
Quan T, Xiang Y, Liu Y, Qin Z, Yang Y, Bou-Gharios G, Voorhees JJ, Dlugosz AA, Fisher GJ. Dermal Fibroblast CCN1 Expression in Mice Recapitulates Human Skin Dermal Aging. The Journal of Investigative Dermatology. PMID 32800875 DOI: 10.1016/J.Jid.2020.07.019 |
0.342 |
|
| 2020 |
El-Zaatari M, Bishu S, Zhang M, Grasberger H, Hou G, Haley HR, Humphries BA, Syu LJ, Dlugosz A, Luker KE, Luker G, Eaton KA, Kamada N, Cascalho M, Kao JY. Aim2-Mediated/IFN-β-Independent Regulation of Gastric Metaplastic Lesions via CD8+ T Cells. Jci Insight. PMID 32053518 DOI: 10.1172/Jci.Insight.94035 |
0.341 |
|
| 2020 |
Grachtchouk M, Wilbert D, Hoover A, Pyrozhenko D, Verhaegen M, Dlugosz AA. LB919 Aging does not facilitate nodular BCC development in mice expressing oncogenic Smo Journal of Investigative Dermatology. 140. DOI: 10.1016/J.Jid.2020.05.007 |
0.325 |
|
| 2020 |
He T, Quan T, Xia W, Dlugosz AA, Voorhees JJ, Fisher GJ. 296 Recombination efficiency and expression of fibroblast-specific Cre drivers in mouse skin Journal of Investigative Dermatology. 140. DOI: 10.1016/J.Jid.2020.03.302 |
0.335 |
|
| 2020 |
Verhaegen ME, Goor JV, Arche J, Harms P, Wilbert D, Zabawa H, Patrick M, Tsoi LC, Chinnaiyan A, Dlugosz AA. 118 In vivo cellular reprogramming facilitates viral T antigen-driven Merkel cell carcinoma development in adult mice Journal of Investigative Dermatology. 140. DOI: 10.1016/J.Jid.2020.03.121 |
0.342 |
|
| 2019 |
Veniaminova NA, Grachtchouk M, Doane OJ, Peterson JK, Quigley DA, Lull MV, Pyrozhenko DV, Nair RR, Patrick MT, Balmain A, Dlugosz AA, Tsoi LC, Wong SY. Niche-Specific Factors Dynamically Regulate Sebaceous Gland Stem Cells in the Skin. Developmental Cell. PMID 31564613 DOI: 10.1016/J.Devcel.2019.08.015 |
0.415 |
|
| 2019 |
Billi AC, Gharaee-Kermani M, Fullmer J, Tsoi LC, Hill BD, Gruszka D, Ludwig J, Xing X, Estadt S, Wolf SJ, Rizvi SM, Berthier CC, Hodgin JB, Beamer MA, Sarkar MK, ... ... Dlugosz AA, et al. The female-biased factor VGLL3 drives cutaneous and systemic autoimmunity. Jci Insight. 4. PMID 30996136 DOI: 10.1172/Jci.Insight.127291 |
0.317 |
|
| 2019 |
Choi JE, Verhaegen ME, Yazdani S, Malik R, Harms PW, Mangelberger D, Tien J, Cao X, Wang Y, Cieślik M, Gurkan J, Yazdani M, Jing X, Juckette K, Su F, ... ... Dlugosz AA, et al. Characterizing the Therapeutic Potential of a Potent BET Degrader in Merkel Cell Carcinoma. Neoplasia (New York, N.Y.). 21: 322-330. PMID 30797188 DOI: 10.1016/J.Neo.2019.01.003 |
0.392 |
|
| 2019 |
Fleming JT, Brignola E, Chen L, Guo Y, Zhao S, Wang Q, Li B, Correa H, Ermilov AN, Dlugosz AA, Chiang C. Insight into the etiology of undifferentiated soft tissue sarcomas from a novel mouse model. Molecular Cancer Research : McR. PMID 30683671 DOI: 10.1158/1541-7786.Mcr-18-0117 |
0.445 |
|
| 2019 |
Veniaminova NA, Grachtchouk M, Doane O, Peterson J, Dlugosz AA, Tsoi A, Wong SY. 879 Dynamic regulation of sebaceous gland stem cells during skin homeostasis and aging Journal of Investigative Dermatology. 139. DOI: 10.1016/J.Jid.2019.03.955 |
0.36 |
|
| 2019 |
Verhaegen ME, Mangelberger D, Wilbert D, VanGoor J, Harms P, Dlugosz AA. 132 Atoh1 is required for maintenance of Merkel cell carcinoma lineage identity Journal of Investigative Dermatology. 139. DOI: 10.1016/J.Jid.2019.03.208 |
0.332 |
|
| 2018 |
Chakrabarti J, Holokai L, Syu L, Steele NG, Chang J, Wang J, Ahmed S, Dlugosz A, Zavros Y. Hedgehog signaling induces PD-L1 expression and tumor cell proliferation in gastric cancer. Oncotarget. 9: 37439-37457. PMID 30647844 DOI: 10.18632/Oncotarget.26473 |
0.383 |
|
| 2018 |
Fan K, Ritter C, Nghiem P, Blom A, Verhaegen ME, Dlugosz A, Odum N, Woetmann A, Tothill RW, Hicks RJ, Sand M, Schrama D, Schadendorf D, Ugurel S, Becker JC. Circulating cell-free miR-375 as surrogate marker of tumor burden in Merkel cell carcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 30061360 DOI: 10.1158/1078-0432.Ccr-18-1184 |
0.413 |
|
| 2018 |
Chakrabarti J, Holokai L, Syu L, Steele N, Chang J, Dlugosz A, Zavros Y. Mouse-Derived Gastric Organoid and Immune Cell Co-culture for the Study of the Tumor Microenvironment. Methods in Molecular Biology (Clifton, N.J.). 1817: 157-168. PMID 29959712 DOI: 10.1007/978-1-4939-8600-2_16 |
0.342 |
|
| 2018 |
Eberl M, Mangelberger D, Swanson JB, Verhaegen ME, Harms PW, Frohm ML, Dlugosz AA, Wong SY. Tumor Architecture and Notch Signaling Modulate Drug Response in Basal Cell Carcinoma. Cancer Cell. PMID 29395868 DOI: 10.1016/J.Ccell.2017.12.015 |
0.46 |
|
| 2018 |
Grachtchouk M, Wilbert D, Hoover A, Dlugosz A. LB1483 Preferential development of nodular basal cell carcinomas from Lgr6+ cells in skin Journal of Investigative Dermatology. 138. DOI: 10.1016/J.Jid.2018.06.012 |
0.385 |
|
| 2018 |
Verhaegen M, Mangelberger D, Harms P, Wilbert D, Zabawa H, Goor JV, Kelly M, Chen P, Dlugosz A. 195 Postnatal initiation of MCC-like tumor development in mice co-expressing Merkel cell polyomavirus T antigens and ATOH1 Journal of Investigative Dermatology. 138. DOI: 10.1016/J.Jid.2018.03.200 |
0.415 |
|
| 2018 |
Zhu X, Leboeuf M, Liu F, Chen S, Olson E, Morrisey E, Dlugosz A, MIllar S. 165 HDAC1 and HDAC2 regulate homeostasis and tumorigenesis of postnatal epidermis Journal of Investigative Dermatology. 138: S28. DOI: 10.1016/J.Jid.2018.03.170 |
0.306 |
|
| 2017 |
Kumari A, Ermilov AN, Grachtchouk M, Dlugosz AA, Allen BL, Bradley RM, Mistretta CM. Recovery of taste organs and sensory function after severe loss from Hedgehog/Smoothened inhibition with cancer drug sonidegib. Proceedings of the National Academy of Sciences of the United States of America. PMID 29133390 DOI: 10.1073/Pnas.1712881114 |
0.354 |
|
| 2017 |
El-Zaatari M, Bass AJ, Bowlby R, Zhang M, Syu LJ, Yang Y, Grasberger H, Shreiner A, Tan B, Bishu S, Leung WK, Todisco A, Kamada N, Cascalho M, Dlugosz AA, et al. Indoleamine 2,3-dioxygenase 1, Increased in Human Gastric Pre-Neoplasia, Promotes Inflammation and Metaplasia in Mice and is Associated with Type II Hypersensitivity/Autoimmunity. Gastroenterology. PMID 28912017 DOI: 10.1053/J.Gastro.2017.09.002 |
0.33 |
|
| 2017 |
Verhaegen ME, Mangelberger D, Harms PW, Eberl M, Wilbert DM, Meireles J, Bichakjian CK, Saunders TL, Wong SY, Dlugosz AA. Merkel cell polyomavirus small T antigen initiates Merkel cell carcinoma-like tumor development in mice. Cancer Research. PMID 28512245 DOI: 10.1158/0008-5472.Can-17-0035 |
0.481 |
|
| 2017 |
Millington G, Elliott K, Chang YT, Chang CF, Dlugosz A, Brugmann SA. Cilia-dependent GLI processing in neural crest cells is required for tongue development. Developmental Biology. PMID 28286175 DOI: 10.1016/J.Ydbio.2017.02.021 |
0.339 |
|
| 2017 |
Xu T, Zhang H, Park SS, Venneti S, Kuick R, Ha K, Michael LE, Santi M, Uchida C, Uchida T, Srinivasan A, Olson JM, Dlugosz AA, Camelo-Piragua S, Rual JF. Loss of Pin1 Suppresses Hedgehog-Driven Medulloblastoma Tumorigenesis. Neoplasia (New York, N.Y.). 19: 216-225. PMID 28167297 DOI: 10.1016/J.Neo.2017.01.002 |
0.761 |
|
| 2017 |
Chakrabarti J, Holokai LL, Bertaux-Skeirik N, Syu L, Broda T, Chang J, Teal EL, Wells J, Dlugosz AA, Zavros Y. Hedgehog Signaling Regulates PDL-1 Expression in Gastric Cancer Cells to Induce Tumor Proliferation Gastroenterology. 152: S1311-S1312. DOI: 10.1016/S0016-5085(17)34367-6 |
0.472 |
|
| 2017 |
Syu L, Verhaegen M, Grachtchouk M, Mangelberger D, Zabawa H, Dlugosz A. 877 Small T antigen from a folliculotropic polyomavirus activates canonical Wnt/β-catenin signaling in vivo Journal of Investigative Dermatology. 137. DOI: 10.1016/J.Jid.2017.02.903 |
0.326 |
|
| 2017 |
Verhaegen ME, Mangelberger D, Harms PW, Eberl M, Wilbert D, Meireles J, Zabawa H, Saunders T, Dlugosz AA. 143 Merkel cell carcinoma-like tumor development in mice is dependent on the FBXW7 binding domain of Merkel cell polyomavirus small T antigen Journal of Investigative Dermatology. 137. DOI: 10.1016/J.Jid.2017.02.157 |
0.395 |
|
| 2016 |
Ermilov AN, Kumari A, Li L, Joiner AM, Grachtchouk MA, Allen BL, Dlugosz AA, Mistretta CM. Maintenance of Taste Organs Is Strictly Dependent on Epithelial Hedgehog/GLI Signaling. Plos Genetics. 12: e1006442. PMID 27893742 DOI: 10.1371/Journal.Pgen.1006442 |
0.467 |
|
| 2016 |
Di Girolamo D, Ambrosio R, De Stefano MA, Mancino G, Porcelli T, Luongo C, Di Cicco E, Scalia G, Vecchio LD, Colao A, Dlugosz AA, Missero C, Salvatore D, Dentice M. Reciprocal interplay between thyroid hormone and microRNA-21 regulates hedgehog pathway-driven skin tumorigenesis. The Journal of Clinical Investigation. 126: 2308-20. PMID 27159391 DOI: 10.1172/Jci84465 |
0.394 |
|
| 2016 |
Syu LJ, Zhao X, Zhang Y, Grachtchouk M, Demitrack E, Ermilov A, Wilbert DM, Zheng X, Kaatz A, Greenson JK, Gumucio DL, Merchant JL, di Magliano MP, Samuelson LC, Dlugosz AA. Invasive mouse gastric adenocarcinomas arising from Lgr5+ stem cells are dependent on crosstalk between the Hedgehog/GLI2 and mTOR pathways. Oncotarget. PMID 26859571 DOI: 10.18632/Oncotarget.7182 |
0.518 |
|
| 2016 |
Harms PW, Collie AM, Hovelson DH, Cani AK, Verhaegen ME, Patel RM, Fullen DR, Omata K, Dlugosz AA, Tomlins SA, Billings SD. Next generation sequencing of Cytokeratin 20-negative Merkel cell carcinoma reveals ultraviolet-signature mutations and recurrent TP53 and RB1 inactivation. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. PMID 26743471 DOI: 10.1038/Modpathol.2015.154 |
0.41 |
|
| 2016 |
Rual JM, Xu T, Zhang H, Park S, Venneti S, Kuick R, Ha K, Michael L, Santi M, Uchida C, Uchida T, Srinivasan A, Dlugosz A, Camelo-Piragua S. Abstract 2447: PIN1 protects GLI1 from ubiquitination and promotes Hedgehog-driven medulloblastoma tumorigenesis Cancer Research. 76: 2447-2447. DOI: 10.1158/1538-7445.Am2016-2447 |
0.765 |
|
| 2016 |
El-Zaatari M, Bass A, Bowlby R, Zhang M, Syu L, Grasberger H, Shreiner A, Kamada N, Cascalho M, Dlugosz AA, Kao JY. 373 Indoleamine-2,3-Dioxygenase-1 (IDO1) Regulates B Cell Maturation and Is Critical for Gastric Pre-Neoplasia Gastroenterology. 150: S83. DOI: 10.1016/S0016-5085(16)30398-5 |
0.31 |
|
| 2016 |
Mangelberger D, Verhaegen M, Harms P, Durham A, Kozlow J, Cederna P, Bichakjian C, Johnson T, Dlugosz A. 098 Co-expression of epidermal keratins and neuroendocrine markers in Merkel cell carcinoma tumors and cell lines Journal of Investigative Dermatology. 136: S18. DOI: 10.1016/J.Jid.2016.02.124 |
0.413 |
|
| 2016 |
Verhaegen ME, Mangelberger D, Harms PW, Wilbert D, Meireles J, Saunders T, Dlugosz AA. 092 Merkel cell polyomavirus small T antigen co-expressed with Atoh1 drives development of intraepidermal MCC Journal of Investigative Dermatology. 136. DOI: 10.1016/J.Jid.2016.02.118 |
0.507 |
|
| 2015 |
Wang B, Merillat SA, Vincent M, Huber AK, Basrur V, Mangelberger D, Zeng L, Elenitoba-Johnson K, Miller RA, Irani DN, Dlugosz AA, Schnell S, Scaglione KM, Paulson HL. Loss of the Ubiquitin-conjugating Enzyme Ube2W results in susceptibility to early postnatal lethality and defects in skin, immune and male reproductive systems. The Journal of Biological Chemistry. PMID 26601958 DOI: 10.1074/Jbc.M115.676601 |
0.368 |
|
| 2015 |
Hammiller BO, El-Abaseri TB, Dlugosz AA, Hansen LA. A Method for the Immortalization of Newborn Mouse Skin Keratinocytes. Frontiers in Oncology. 5: 177. PMID 26284198 DOI: 10.3389/Fonc.2015.00177 |
0.357 |
|
| 2015 |
Harms PW, Vats P, Verhaegen ME, Robinson DR, Wu YM, Dhanasekaran SM, Palanisamy N, Siddiqui J, Cao X, Su F, Wang R, Xiao H, Kunju LP, Mehra R, Tomlins SA, ... ... Dlugosz AA, et al. The Distinctive Mutational Spectra of Polyomavirus-Negative Merkel Cell Carcinoma. Cancer Research. PMID 26238782 DOI: 10.1158/0008-5472.Can-15-0702 |
0.354 |
|
| 2015 |
Peterson SC, Eberl M, Vagnozzi AN, Belkadi A, Veniaminova NA, Verhaegen ME, Bichakjian CK, Ward NL, Dlugosz AA, Wong SY. Basal cell carcinoma preferentially arises from stem cells within hair follicle and mechanosensory niches. Cell Stem Cell. 16: 400-12. PMID 25842978 DOI: 10.1016/j.stem.2015.02.006 |
0.417 |
|
| 2015 |
Sharpe HJ, Pau G, Dijkgraaf GJ, Basset-Seguin N, Modrusan Z, Januario T, Tsui V, Durham AB, Dlugosz AA, Haverty PM, Bourgon R, Tang JY, Sarin KY, Dirix L, Fisher DC, et al. Genomic analysis of smoothened inhibitor resistance in basal cell carcinoma. Cancer Cell. 27: 327-41. PMID 25759019 DOI: 10.1016/J.Ccell.2015.02.001 |
0.384 |
|
| 2015 |
Kern D, Regl G, Hofbauer SW, Altenhofer P, Achatz G, Dlugosz A, Schnidar H, Greil R, Hartmann TN, Aberger F. Hedgehog/GLI and PI3K signaling in the initiation and maintenance of chronic lymphocytic leukemia. Oncogene. PMID 25639866 DOI: 10.1038/Onc.2014.450 |
0.481 |
|
| 2015 |
Kumari A, Ermilov AN, Allen BL, Bradley RM, Dlugosz AA, Mistretta CM. Hedgehog pathway blockade with the cancer drug LDE225 disrupts taste organs and taste sensation. Journal of Neurophysiology. 113: 1034-40. PMID 25392175 DOI: 10.1152/Jn.00822.2014 |
0.366 |
|
| 2015 |
Verhaegen ME, Mangelberger D, Harms PW, Vozheiko TD, Weick JW, Wilbert DM, Saunders TL, Ermilov AN, Bichakjian CK, Johnson TM, Imperiale MJ, Dlugosz AA. Merkel cell polyomavirus small T antigen is oncogenic in transgenic mice. The Journal of Investigative Dermatology. 135: 1415-24. PMID 25313532 DOI: 10.1038/Jid.2014.446 |
0.325 |
|
| 2015 |
Xu T, Zhang H, Park SS, Camelo-Piragua S, Dlugosz A, Venneti S, Kuick R, Uchida T, Rual J. PTPS-26PIN1, A THERAPEUTIC TARGET IN HEDGEHOG-DRIVEN MEDULLOBLASTOMA Neuro-Oncology. 17: v184.5-v185. DOI: 10.1093/Neuonc/Nov228.26 |
0.495 |
|
| 2014 |
Luongo C, Ambrosio R, Salzano S, Dlugosz AA, Missero C, Dentice M. The sonic hedgehog-induced type 3 deiodinase facilitates tumorigenesis of basal cell carcinoma by reducing Gli2 inactivation. Endocrinology. 155: 2077-88. PMID 24693967 DOI: 10.1210/En.2013-2108 |
0.406 |
|
| 2013 |
Liu HX, Ermilov A, Grachtchouk M, Li L, Gumucio DL, Dlugosz AA, Mistretta CM. Multiple Shh signaling centers participate in fungiform papilla and taste bud formation and maintenance. Developmental Biology. 382: 82-97. PMID 23916850 DOI: 10.1016/J.Ydbio.2013.07.022 |
0.4 |
|
| 2013 |
Harms PW, Patel RM, Verhaegen ME, Giordano TJ, Nash KT, Johnson CN, Daignault S, Thomas DG, Gudjonsson JE, Elder JT, Dlugosz AA, Johnson TM, Fullen DR, Bichakjian CK. Distinct gene expression profiles of viral- and nonviral-associated merkel cell carcinoma revealed by transcriptome analysis. The Journal of Investigative Dermatology. 133: 936-45. PMID 23223137 DOI: 10.1038/Jid.2012.445 |
0.422 |
|
| 2012 |
Saqui-Salces M, Covés-Datson E, Veniaminova NA, Waghray M, Syu LJ, Dlugosz AA, Merchant JL. Inflammation and Gli2 suppress gastrin gene expression in a murine model of antral hyperplasia. Plos One. 7: e48039. PMID 23110168 DOI: 10.1371/Journal.Pone.0048039 |
0.378 |
|
| 2012 |
Yuspa SH, Kraemer KH, Dlugosz AA, Roop DR, Kulesz-Martin M, Bickenbach JR. Montagna Symposium 2011: 60th Anniversary--Advances in Science and Medicine Catalyzed by Pioneering Skin Research. The Journal of Investigative Dermatology. 132: 1317-20. PMID 22499034 DOI: 10.1038/Jid.2011.480 |
0.34 |
|
| 2012 |
Eberl M, Klingler S, Mangelberger D, Loipetzberger A, Damhofer H, Zoidl K, Schnidar H, Hache H, Bauer HC, Solca F, Hauser-Kronberger C, Ermilov AN, Verhaegen ME, Bichakjian CK, Dlugosz AA, et al. Hedgehog-EGFR cooperation response genes determine the oncogenic phenotype of basal cell carcinoma and tumour-initiating pancreatic cancer cells. Embo Molecular Medicine. 4: 218-33. PMID 22294553 DOI: 10.1002/Emmm.201100201 |
0.462 |
|
| 2012 |
Wong S, Epstein E, Dlugosz A, Reiter J. Abstract SY37-01: Cilia and wounding cooperate with Hedgehog signaling to initiate basal cell carcinoma Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Sy37-01 |
0.536 |
|
| 2011 |
Grachtchouk M, Pero J, Yang SH, Ermilov AN, Michael LE, Wang A, Wilbert D, Patel RM, Ferris J, Diener J, Allen M, Lim S, Syu LJ, Verhaegen M, Dlugosz AA. Basal cell carcinomas in mice arise from hair follicle stem cells and multiple epithelial progenitor populations. The Journal of Clinical Investigation. 121: 1768-81. PMID 21519145 DOI: 10.1172/Jci46307 |
0.787 |
|
| 2011 |
Qiao XT, Samuelson LC, Dlugosz A, Merchant JL, Gumucio DL. Villin-Marked Gastric Epithelial Progenitor Cells Do Not Give Rise to Tumors or Metaplastic Cells in a Variety of Mouse Models Gastroenterology. 140: S-830. DOI: 10.1016/S0016-5085(11)63439-2 |
0.424 |
|
| 2011 |
Ermilov A, Ferris J, Pero J, Qiao XT, Greenson JK, Gumucio DL, Dlugosz A. Deregulated Hedgehog Signaling in the Pathogenesis of Barrett's Disease and Gastric Adenocarcinoma Gastroenterology. 140: S-157. DOI: 10.1016/S0016-5085(11)60639-2 |
0.305 |
|
| 2011 |
Covés-Datson E, Saqui-Salces M, Waghray M, Merchant JL, Dlugosz A. Induction of Follistatin in Metaplastic Antra of Gastrin Null Mice Correlates With Increased Hedgehog Signaling Gastroenterology. 140: S-92. DOI: 10.1016/S0016-5085(11)60375-2 |
0.383 |
|
| 2010 |
Depianto D, Kerns ML, Dlugosz AA, Coulombe PA. Keratin 17 promotes epithelial proliferation and tumor growth by polarizing the immune response in skin. Nature Genetics. 42: 910-4. PMID 20871598 DOI: 10.1038/Ng.665 |
0.447 |
|
| 2010 |
Cheng X, Jin J, Hu L, Shen D, Dong XP, Samie MA, Knoff J, Eisinger B, Liu ML, Huang SM, Caterina MJ, Dempsey P, Michael LE, Dlugosz AA, Andrews NC, et al. TRP channel regulates EGFR signaling in hair morphogenesis and skin barrier formation. Cell. 141: 331-43. PMID 20403327 DOI: 10.1016/J.Cell.2010.03.013 |
0.739 |
|
| 2010 |
Syu L, Ferris J, Qiao X, Tetarbe M, Merchant JL, Gumucio DL, Dlugosz A. 584 Transgenic Expression of Interferon Gamma in the Gastric Corpus Leads to Inflammation, Progenitor Cell Expansion, and Mucous Metaplasia Gastroenterology. 138: S-83. DOI: 10.1016/S0016-5085(10)60379-4 |
0.329 |
|
| 2009 |
Wong SY, Seol AD, So PL, Ermilov AN, Bichakjian CK, Epstein EH, Dlugosz AA, Reiter JF. Primary cilia can both mediate and suppress Hedgehog pathway-dependent tumorigenesis. Nature Medicine. 15: 1055-61. PMID 19701205 DOI: 10.1038/Nm.2011 |
0.521 |
|
| 2009 |
Han YG, Kim HJ, Dlugosz AA, Ellison DW, Gilbertson RJ, Alvarez-Buylla A. Dual and opposing roles of primary cilia in medulloblastoma development. Nature Medicine. 15: 1062-5. PMID 19701203 DOI: 10.1038/Nm.2020 |
0.479 |
|
| 2009 |
Sharov AA, Mardaryev AN, Sharova TY, Grachtchouk M, Atoyan R, Byers HR, Seykora JT, Overbeek P, Dlugosz A, Botchkarev VA. Bone morphogenetic protein antagonist noggin promotes skin tumorigenesis via stimulation of the Wnt and Shh signaling pathways. The American Journal of Pathology. 175: 1303-14. PMID 19700758 DOI: 10.2353/Ajpath.2009.090163 |
0.517 |
|
| 2009 |
Kolterud A, Grosse AS, Zacharias WJ, Walton KD, Kretovich KE, Madison BB, Waghray M, Ferris JE, Hu C, Merchant JL, Dlugosz AA, Kottmann AH, Gumucio DL. Paracrine Hedgehog signaling in stomach and intestine: new roles for hedgehog in gastrointestinal patterning. Gastroenterology. 137: 618-28. PMID 19445942 DOI: 10.1053/J.Gastro.2009.05.002 |
0.427 |
|
| 2009 |
Fan Z, Du J, Liu H, Zhang H, Dlugosz AA, Wang CY, Fan M, Shen Y, Wang S. A susceptibility locus on 1p32-1p34 for congenital macrostomia in a Chinese family and identification of a novel PTCH2 mutation. American Journal of Medical Genetics. Part A. 149: 521-4. PMID 19208383 DOI: 10.1002/Ajmg.A.32647 |
0.328 |
|
| 2009 |
Gudjonsson JE, Aphale A, Grachtchouk M, Ding J, Nair RP, Wang T, Voorhees JJ, Dlugosz AA, Elder JT. Lack of evidence for activation of the hedgehog pathway in psoriasis. The Journal of Investigative Dermatology. 129: 635-40. PMID 18754037 DOI: 10.1038/Jid.2008.266 |
0.4 |
|
| 2008 |
Yang SH, Andl T, Grachtchouk V, Wang A, Liu J, Syu LJ, Ferris J, Wang TS, Glick AB, Millar SE, Dlugosz AA. Pathological responses to oncogenic Hedgehog signaling in skin are dependent on canonical Wnt/beta3-catenin signaling. Nature Genetics. 40: 1130-5. PMID 19165927 DOI: 10.1038/Ng.192 |
0.489 |
|
| 2008 |
Michael LE, Westerman BA, Ermilov AN, Wang A, Ferris J, Liu J, Blom M, Ellison DW, van Lohuizen M, Dlugosz AA. Bmi1 is required for Hedgehog pathway-driven medulloblastoma expansion. Neoplasia (New York, N.Y.). 10: 1343-9, 5p following. PMID 19048113 DOI: 10.1593/Neo.81078 |
0.772 |
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| 2008 |
Liu F, Chu EY, Watt B, Zhang Y, Gallant NM, Andl T, Yang SH, Lu MM, Piccolo S, Schmidt-Ullrich R, Taketo MM, Morrisey EE, Atit R, Dlugosz AA, Millar SE. Wnt/beta-catenin signaling directs multiple stages of tooth morphogenesis. Developmental Biology. 313: 210-24. PMID 18022614 DOI: 10.1016/J.Ydbio.2007.10.016 |
0.42 |
|
| 2008 |
Zhang Y, Andl T, Liu F, Yang SH, Taketo MM, Dlugosz AA, Millar SE. Constitutive activation of β-catenin signaling in embryonic surface epithelium results in global acquisition of hair follicle fate Developmental Biology. 319: 537. DOI: 10.1016/J.Ydbio.2008.05.258 |
0.35 |
|
| 2007 |
Pasca di Magliano M, Biankin AV, Heiser PW, Cano DA, Gutierrez PJ, Deramaudt T, Segara D, Dawson AC, Kench JG, Henshall SM, Sutherland RL, Dlugosz A, Rustgi AK, Hebrok M. Common activation of canonical Wnt signaling in pancreatic adenocarcinoma. Plos One. 2: e1155. PMID 17982507 DOI: 10.1371/Journal.Pone.0001155 |
0.462 |
|
| 2007 |
Zavros Y, Waghray M, Tessier A, Bai L, Todisco A, L Gumucio D, Samuelson LC, Dlugosz A, Merchant JL. Reduced pepsin A processing of sonic hedgehog in parietal cells precedes gastric atrophy and transformation. The Journal of Biological Chemistry. 282: 33265-74. PMID 17872943 DOI: 10.1074/Jbc.M707090200 |
0.337 |
|
| 2007 |
Bradley SV, Hyun TS, Oravecz-Wilson KI, Li L, Waldorff EI, Ermilov AN, Goldstein SA, Zhang CX, Drubin DG, Varela K, Parlow A, Dlugosz AA, Ross TS. Degenerative phenotypes caused by the combined deficiency of murine HIP1 and HIP1r are rescued by human HIP1. Human Molecular Genetics. 16: 1279-92. PMID 17452370 DOI: 10.1093/Hmg/Ddm076 |
0.336 |
|
| 2007 |
Vasireddy V, Uchida Y, Salem N, Kim SY, Mandal MN, Reddy GB, Bodepudi R, Alderson NL, Brown JC, Hama H, Dlugosz A, Elias PM, Holleran WM, Ayyagari R. Loss of functional ELOVL4 depletes very long-chain fatty acids (> or =C28) and the unique omega-O-acylceramides in skin leading to neonatal death. Human Molecular Genetics. 16: 471-82. PMID 17208947 DOI: 10.1093/Hmg/Ddl480 |
0.323 |
|
| 2007 |
Liu F, Thirumangalathu S, Gallant NM, Yang SH, Stoick-Cooper CL, Reddy ST, Andl T, Taketo MM, Dlugosz AA, Moon RT, Barlow LA, Millar SE. Wnt-beta-catenin signaling initiates taste papilla development. Nature Genetics. 39: 106-12. PMID 17128274 DOI: 10.1038/Ng1932 |
0.351 |
|
| 2006 |
Grachtchouk M, Liu J, Wang A, Wei L, Bichakjian CK, Garlick J, Paulino AF, Giordano T, Dlugosz AA. Odontogenic keratocysts arise from quiescent epithelial rests and are associated with deregulated hedgehog signaling in mice and humans. The American Journal of Pathology. 169: 806-14. PMID 16936257 DOI: 10.2353/Ajpath.2006.060054 |
0.414 |
|
| 2006 |
Bhatia N, Thiyagarajan S, Elcheva I, Saleem M, Dlugosz A, Mukhtar H, Spiegelman VS. Gli2 is targeted for ubiquitination and degradation by beta-TrCP ubiquitin ligase. The Journal of Biological Chemistry. 281: 19320-6. PMID 16651270 DOI: 10.1074/Jbc.M513203200 |
0.403 |
|
| 2005 |
Hutchin ME, Kariapper MS, Grachtchouk M, Wang A, Wei L, Cummings D, Liu J, Michael LE, Glick A, Dlugosz AA. Sustained Hedgehog signaling is required for basal cell carcinoma proliferation and survival: conditional skin tumorigenesis recapitulates the hair growth cycle. Genes & Development. 19: 214-23. PMID 15625189 DOI: 10.1101/Gad.1258705 |
0.792 |
|
| 2004 |
Brancaccio A, Minichiello A, Grachtchouk M, Antonini D, Sheng H, Parlato R, Dathan N, Dlugosz AA, Missero C. Requirement of the forkhead gene Foxe1, a target of sonic hedgehog signaling, in hair follicle morphogenesis. Human Molecular Genetics. 13: 2595-606. PMID 15367491 DOI: 10.1093/hmg/ddh292 |
0.368 |
|
| 2004 |
Cui C, Elsam T, Tian Q, Seykora JT, Grachtchouk M, Dlugosz A, Tseng H. Gli proteins up-regulate the expression of basonuclin in Basal cell carcinoma. Cancer Research. 64: 5651-8. PMID 15313903 DOI: 10.1158/0008-5472.CAN-04-0801 |
0.358 |
|
| 2003 |
Allen M, Grachtchouk M, Sheng H, Grachtchouk V, Wang A, Wei L, Liu J, Ramirez A, Metzger D, Chambon P, Jorcano J, Dlugosz AA. Hedgehog signaling regulates sebaceous gland development. The American Journal of Pathology. 163: 2173-8. PMID 14633591 DOI: 10.1016/S0002-9440(10)63574-2 |
0.401 |
|
| 2003 |
Grachtchouk V, Grachtchouk M, Lowe L, Johnson T, Wei L, Wang A, de Sauvage F, Dlugosz AA. The magnitude of hedgehog signaling activity defines skin tumor phenotype. The Embo Journal. 22: 2741-51. PMID 12773389 DOI: 10.1093/emboj/cdg271 |
0.424 |
|
| 2003 |
Mill P, Mo R, Fu H, Grachtchouk M, Kim PC, Dlugosz AA, Hui CC. Sonic hedgehog-dependent activation of Gli2 is essential for embryonic hair follicle development. Genes & Development. 17: 282-94. PMID 12533516 DOI: 10.1101/gad.1038103 |
0.388 |
|
| 2002 |
Dlugosz A, Merlino G, Yuspa SH. Progress in cutaneous cancer research. Journal of Investigative Dermatology Symposium Proceedings. 7: 17-26. PMID 12518788 DOI: 10.1046/J.1523-1747.2002.19631.X |
0.328 |
|
| 2002 |
Sheng H, Goich S, Wang A, Grachtchouk M, Lowe L, Mo R, Lin K, de Sauvage FJ, Sasaki H, Hui CC, Dlugosz AA. Dissecting the oncogenic potential of Gli2: deletion of an NH(2)-terminal fragment alters skin tumor phenotype. Cancer Research. 62: 5308-16. PMID 12235001 |
0.373 |
|
| 2000 |
Denning MF, Dlugosz AA, Cheng C, Dempsey PJ, Coffey RJ, Threadgill DW, Magnuson T, Yuspa SH. Cross-talk between epidermal growth factor receptor and protein kinase C during calcium-induced differentiation of keratinocytes Experimental Dermatology. 9: 192-199. PMID 10839717 DOI: 10.1034/J.1600-0625.2000.009003192.X |
0.353 |
|
| 1999 |
Ding Q, Fukami SI, Meng X, Nishizaki Y, Zhang X, Sasaki H, Dlugosz A, Nakafuku M, Hui CC. Mouse suppressor of fused is a negative regulator of Sonic hedgehog signaling and alters the subcellular distribution of Gli1 Current Biology. 9: 1119-1122. PMID 10531011 DOI: 10.1016/S0960-9822(99)80482-5 |
0.353 |
|
| 1999 |
Dlugosz A. The Hedgehog and the hair follicle: a growing relationship. Journal of Clinical Investigation. 104: 851-853. PMID 10510325 DOI: 10.1172/Jci8416 |
0.324 |
|
| 1999 |
Chiang C, Swan RZ, Grachtchouk M, Bolinger M, Litingtung Y, Robertson EK, Cooper MK, Gaffield W, Westphal H, Beachy PA, Dlugosz AA. Essential role for Sonic hedgehog during hair follicle morphogenesis. Developmental Biology. 205: 1-9. PMID 9882493 DOI: 10.1006/Dbio.1998.9103 |
0.446 |
|
| 1998 |
Lee YS, Yuspa SH, Dlugosz AA. Differentiation of cultured human epidermal keratinocytes at high cell densities is mediated by endogenous activation of the protein kinase C signaling pathway. The Journal of Investigative Dermatology. 111: 762-6. PMID 9804335 DOI: 10.1046/J.1523-1747.1998.00365.X |
0.309 |
|
| 1998 |
Chiang C, Litingtung Y, Bolinger M, Beachy P, Westphal H, Dlugosz A. Targeted disruption of Sonic hedgehog reveals an essential role in hair follicle morphogenesis Journal of Dermatological Science. 16: S2. DOI: 10.1016/S0923-1811(98)83007-7 |
0.324 |
|
| 1996 |
Stanwell C, Dlugosz AA, Yuspa SH. Staurosporine induces a complete program of terminal differentiation in neoplastic mouse keratinocytes via activation of protein kinase C Carcinogenesis. 17: 1259-1265. PMID 8681440 DOI: 10.1093/Carcin/17.6.1259 |
0.412 |
|
| 1996 |
Stanwell C, Denning MF, Rutberg SE, Cheng C, Yuspa SH, Dlugosz AA. Staurosporine induces a sequential program of mouse keratinocyte terminal differentiation through activation of PKC isozymes Journal of Investigative Dermatology. 106: 482-489. PMID 8648181 DOI: 10.1111/1523-1747.Ep12343690 |
0.408 |
|
| 1996 |
Dlugosz AA, Glick AB, Tennenbaum T, Weinberg WC, Yuspa SH. Isolation and utilization of epidermal keratinocytes for oncogene research. Methods in Enzymology. 254: 3-20. PMID 8531694 DOI: 10.1016/0076-6879(95)54003-2 |
0.375 |
|
| 1994 |
Yuspa SH, Dlugosz AA, Cheng CK, Denning MF, Tennenbaum T, Glick AB, Weinberg WC. Role of oncogenes and tumor suppressor genes in multistage carcinogenesis Journal of Investigative Dermatology. 103. PMID 7963691 DOI: 10.1038/Jid.1994.16 |
0.462 |
|
| 1994 |
Dlugosz AA, Yuspa SH. Protein kinase C regulates keratinocyte transglutaminase (TGK) gene expression in cultured primary mouse epidermal keratinocytes induced to terminally differentiate by calcium Journal of Investigative Dermatology. 102: 409-414. PMID 7908680 DOI: 10.1111/1523-1747.Ep12372171 |
0.312 |
|
| 1993 |
Strickland JE, Dlugosz AA, Hennings H, Yuspa SH. Inhibition of tumor formation from grafted murine papilloma cells by treatment of grafts with staurosporine, an inducer of squamous differentiation. Carcinogenesis. 14: 205-209. PMID 8435862 DOI: 10.1093/Carcin/14.2.205 |
0.426 |
|
| 1993 |
Dlugosz AA, Yuspa SH. Coordinate changes in gene expression which mark the spinous to granular cell transition in epidermis are regulated by protein kinase C. Journal of Cell Biology. 120: 217-225. PMID 7678013 DOI: 10.1083/Jcb.120.1.217 |
0.352 |
|
| 1993 |
Dlugosz AA, Cheng C, Denning MF, Dempsey PJ, Coffey RJ, Yuspa SH. KGF induces TGFα expression and activates the EGF receptor signaling pathway to alter keratinocyte growth and differentiation in vitro Journal of Dermatological Science. 6: 41. DOI: 10.1016/0923-1811(93)90954-N |
0.413 |
|
| 1992 |
Lee E, Punnonen K, Cheng C, Click A, Dlugosz A, Yuspa SH. Analysis of phospholipid metabolism in murine keratinocytes transformed by the v-ras oncogene: relationship of phosphatidylinositol turnover and cytokine stimulation to the transformed phenotype. Carcinogenesis. 13: 2367-2373. PMID 1473246 DOI: 10.1093/Carcin/13.12.2367 |
0.314 |
|
| 1992 |
Dlugosz AA, Mischak H, Mushinski JF, Yuspa SH. Transcripts encoding protein kinase C-alpha, -delta, -epsilon, -zeta, and -eta are expressed in basal and differentiating mouse keratinocytes in vitro and exhibit quantitative changes in neoplastic cells. Molecular Carcinogenesis. 5: 286-92. PMID 1379814 DOI: 10.1002/Mc.2940050409 |
0.34 |
|
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