| Year |
Citation |
Score |
| 2024 |
Goswami D, Patel H, Betz W, Armstrong J, Camargo N, Patil A, Chakravarty S, Murphy SC, Sim BKL, Vaughan AM, Hoffman SL, Kappe SH. A replication competent Plasmodium falciparum parasite completely attenuated by dual gene deletion. Embo Molecular Medicine. PMID 38514791 DOI: 10.1038/s44321-024-00057-7 |
0.51 |
|
| 2020 |
Goswami D, Betz W, Locham NK, Parthiban C, Brager C, Schäfer C, Camargo N, Nguyen T, Kennedy SY, Murphy SC, Vaughan AM, Kappe SH. A replication-competent late liver stage-attenuated human malaria parasite. Jci Insight. PMID 32484795 DOI: 10.1172/jci.insight.135589 |
0.569 |
|
| 2019 |
Healy SA, Murphy SC, Hume JCC, Shelton L, Kuntz S, Van Voorhis WC, Moodie Z, Metch B, Wang R, Silver-Brace T, Fishbaugher M, Kennedy M, Finney OC, Chaturvedi R, Hobbs CV, ... ... Kappe SH, et al. Chemoprophylaxis vaccination: Phase 1 study to explore stage-specific immunity to Plasmodium falciparum in U.S. adults. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 31621832 DOI: 10.1093/Cid/Ciz1010 |
0.56 |
|
| 2019 |
Gupta DK, Dembele L, Voorberg-van der Wel A, Roma G, Yip A, Chuenchob V, Kangwanrangsan N, Ishino T, Vaughan AM, Kappe SH, Flannery EL, Sattabongkot J, Mikolajczak SA, Bifani P, Kocken CHM, et al. The Liver-Specific Protein 2 (LISP2) is an early marker of liver stage development. Elife. 8. PMID 31094679 DOI: 10.7554/Elife.43362 |
0.569 |
|
| 2019 |
Gupta DK, Dembele L, Wel AVd, Roma G, Yip A, Chuenchob V, Kangwanrangsan N, Ishino T, Vaughan AM, Kappe SH, Flannery EL, Sattabongkot J, Mikolajczak S, Bifani P, Kocken CH, et al. Author response: The Plasmodium liver-specific protein 2 (LISP2) is an early marker of liver stage development Elife. DOI: 10.7554/Elife.43362.033 |
0.447 |
|
| 2018 |
Hahn WO, Butler NS, Lindner SE, Akilesh HM, Sather DN, Kappe SH, Hamerman JA, Gale M, Liles WC, Pepper M. cGAS-mediated control of blood-stage malaria promotes Plasmodium-specific germinal center responses. Jci Insight. 3. PMID 29367469 DOI: 10.1172/Jci.Insight.94142 |
0.7 |
|
| 2018 |
Flannery EL, Foquet L, Chuenchob V, Fishbaugher M, Billman Z, Navarro MJ, Betz W, Olsen TM, Lee J, Camargo N, Nguyen T, Schafer C, Sack BK, Wilson EM, Saunders J, ... ... Kappe SH, et al. Assessing drug efficacy against Plasmodium falciparum liver stages in vivo. Jci Insight. 3. PMID 29321371 DOI: 10.1172/jci.insight.92587 |
0.488 |
|
| 2018 |
Scally SW, Murugan R, Triller G, Imkeller K, Bosch A, Costa G, Pissarev M, Kreschel C, Marois E, Sack BK, Salman AM, Janse CJ, Khan SM, Kappe SH, Adegnika AA, et al. Structural studies of human antibody responses against leading malaria vaccine antigen PfCSP Acta Crystallographica Section a Foundations and Advances. 74: a207-a207. DOI: 10.1107/S0108767318097921 |
0.311 |
|
| 2017 |
Murphy SC, Duke ER, Shipman KJ, Jensen RL, Fong Y, Ferguson S, Janes HE, Gillespie K, Seilie AM, Hanron AE, Rinn L, Fishbaugher M, VonGoedert T, Fritzen E, Kappe SH, et al. A randomized trial of the prophylactic activity of DSM265 against pre-erythrocytic Plasmodium falciparum controlled human malaria infection by mosquito bites and direct venous inoculation. The Journal of Infectious Diseases. PMID 29216395 DOI: 10.1093/Infdis/Jix613 |
0.497 |
|
| 2017 |
Ortega C, Frando A, Webb-Robertson BJ, Anderson LN, Fleck ND, Flannery EL, Fishbaugher M, Murphree TA, Hansen JR, Smith RD, Kappe SH, Wright A, Grundner C. A global survey of ATPase activity in Plasmodium falciparum asexual blood stages and gametocytes. Molecular & Cellular Proteomics : McP. PMID 29079720 DOI: 10.1074/Mcp.Ra117.000088 |
0.397 |
|
| 2017 |
Hanron AE, Billman ZP, Seilie AM, Olsen TM, Fishbaugher M, Chang M, Rueckle T, Andenmatten N, Greenhouse B, Arinaitwe E, Rek J, Das S, Domingo GJ, Shipman K, Kappe SH, et al. Multiplex, DNase-free one-step reverse transcription PCR for Plasmodium 18S rRNA and spliced gametocyte-specific mRNAs. Malaria Journal. 16: 208. PMID 28526032 DOI: 10.1186/S12936-017-1863-3 |
0.391 |
|
| 2017 |
Sack B, Kappe SH, Sather DN. Towards functional antibody-based vaccines to prevent pre-erythrocytic malaria infection. Expert Review of Vaccines. 1-12. PMID 28277097 DOI: 10.1080/14760584.2017.1295853 |
0.398 |
|
| 2017 |
Vaughan AM, Kappe SH. Malaria Parasite Liver Infection and Exoerythrocytic Biology. Cold Spring Harbor Perspectives in Medicine. PMID 28242785 DOI: 10.1101/cshperspect.a025486 |
0.626 |
|
| 2017 |
Kublin JG, Mikolajczak SA, Sack BK, Fishbaugher ME, Seilie A, Shelton L, VonGoedert T, Firat M, Magee S, Fritzen E, Betz W, Kain HS, Dankwa DA, Steel RW, Vaughan AM, ... ... Kappe SH, et al. Complete attenuation of genetically engineered Plasmodium falciparum sporozoites in human subjects. Science Translational Medicine. 9. PMID 28053159 DOI: 10.1126/scitranslmed.aad9099 |
0.46 |
|
| 2016 |
Keitany GJ, Kim KS, Krishnamurty AT, Hondowicz BD, Hahn WO, Dambrauskas N, Sather DN, Vaughan AM, Kappe SH, Pepper M. Blood Stage Malaria Disrupts Humoral Immunity to the Pre-erythrocytic Stage Circumsporozoite Protein. Cell Reports. 17: 3193-3205. PMID 28009289 DOI: 10.1016/J.Celrep.2016.11.060 |
0.508 |
|
| 2016 |
Arredondo SA, Kappe SH. The s48/45 six-cysteine proteins: mediators of interaction throughout the Plasmodium life cycle. International Journal For Parasitology. PMID 27899328 DOI: 10.1016/j.ijpara.2016.10.002 |
0.423 |
|
| 2016 |
Steel RW, Sack BK, Tsuji M, Kappe SH. An opsonic phagocytosis assay for Plasmodium falciparum sporozoites. Clinical and Vaccine Immunology : Cvi. PMID 27881488 DOI: 10.1128/Cvi.00445-16 |
0.352 |
|
| 2016 |
Steel RW, Kappe SH, Sack BK. An expanding toolkit for preclinical pre-erythrocytic malaria vaccine development: bridging traditional mouse malaria models and human trials. Future Microbiology. PMID 27855488 DOI: 10.2217/Fmb-2016-0077 |
0.598 |
|
| 2016 |
Speake C, Pichugin A, Sahu T, Malkov V, Morrison R, Pei Y, Juompan L, Milman N, Zarling S, Anderson C, Wong-Madden S, Wendler J, Ishizuka A, MacMillen ZW, Garcia V, ... Kappe SH, et al. Identification of Novel Pre-Erythrocytic Malaria Antigen Candidates for Combination Vaccines with Circumsporozoite Protein. Plos One. 11: e0159449. PMID 27434123 DOI: 10.1371/Journal.Pone.0159449 |
0.379 |
|
| 2016 |
Swearingen KE, Lindner SE, Shi L, Shears MJ, Harupa A, Hopp CS, Vaughan AM, Springer TA, Moritz RL, Kappe SH, Sinnis P. Interrogating the Plasmodium Sporozoite Surface: Identification of Surface-Exposed Proteins and Demonstration of Glycosylation on CSP and TRAP by Mass Spectrometry-Based Proteomics. Plos Pathogens. 12: e1005606. PMID 27128092 DOI: 10.1371/Journal.Ppat.1005606 |
0.656 |
|
| 2016 |
Dankwa DA, Davis MJ, Kappe SH, Vaughan AM. A Plasmodium Mei2-like RNA Binding Protein is essential for completion of liver stage schizogony. Infection and Immunity. PMID 26883588 DOI: 10.1128/IAI.01417-15 |
0.525 |
|
| 2015 |
Kaushansky A, Douglass AN, Arang N, Vigdorovich V, Dambrauskas N, Kain HS, Austin LS, Sather DN, Kappe SH. Malaria parasites target the hepatocyte receptor EphA2 for successful host infection. Science (New York, N.Y.). 350: 1089-92. PMID 26612952 DOI: 10.1126/Science.Aad3318 |
0.795 |
|
| 2015 |
Bijker EM, Borrmann S, Kappe SH, Mordmüller B, Sack BK, Khan SM. Novel approaches to whole sporozoite vaccination against malaria. Vaccine. PMID 26469716 DOI: 10.1016/J.Vaccine.2015.09.095 |
0.392 |
|
| 2015 |
Sack BK, Miller JL, Vaughan AM, Kappe SH. Measurement of Antibody-Mediated Reduction of Plasmodium yoelii Liver Burden by Bioluminescent Imaging. Methods in Molecular Biology (Clifton, N.J.). 1325: 69-80. PMID 26450380 DOI: 10.1007/978-1-4939-2815-6_6 |
0.525 |
|
| 2015 |
Douglass AN, Metzger PG, Kappe SH, Kaushansky A. Flow Cytometry-Based Assessment of Antibody Function Against Malaria Pre-erythrocytic Infection. Methods in Molecular Biology (Clifton, N.J.). 1325: 49-58. PMID 26450378 DOI: 10.1007/978-1-4939-2815-6_4 |
0.726 |
|
| 2015 |
Kaushansky A, Kappe SH. Host ER stress during malaria parasite infection. Embo Reports. 16: 883-4. PMID 26138101 DOI: 10.15252/Embr.201540792 |
0.789 |
|
| 2015 |
Groat-Carmona AM, Kain H, Brownell J, Douglass AN, Aly AS, Kappe SH. A Plasmodium α/β-hydrolase modulates the development of invasive stages. Cellular Microbiology. 17: 1848-67. PMID 26118838 DOI: 10.1111/Cmi.12477 |
0.574 |
|
| 2015 |
Kaushansky A, Kappe SH. Selection and refinement: the malaria parasite's infection and exploitation of host hepatocytes. Current Opinion in Microbiology. 26: 71-8. PMID 26102161 DOI: 10.1016/J.Mib.2015.05.013 |
0.803 |
|
| 2015 |
Vaughan AM, Pinapati RS, Cheeseman IH, Camargo N, Fishbaugher M, Checkley LA, Nair S, Hutyra CA, Nosten FH, Anderson TJ, Ferdig MT, Kappe SH. Plasmodium falciparum genetic crosses in a humanized mouse model. Nature Methods. 12: 631-3. PMID 26030447 DOI: 10.1038/Nmeth.3432 |
0.374 |
|
| 2015 |
Sack BK, Keitany GJ, Vaughan AM, Miller JL, Wang R, Kappe SH. Mechanisms of stage-transcending protection following immunization of mice with late liver stage-arresting genetically attenuated malaria parasites. Plos Pathogens. 11: e1004855. PMID 25974076 DOI: 10.1371/journal.ppat.1004855 |
0.513 |
|
| 2015 |
Mikolajczak SA, Vaughan AM, Kangwanrangsan N, Roobsoong W, Fishbaugher M, Yimamnuaychok N, Rezakhani N, Lakshmanan V, Singh N, Kaushansky A, Camargo N, Baldwin M, Lindner SE, Adams JH, Sattabongkot J, ... Kappe SH, et al. Plasmodium vivax liver stage development and hypnozoite persistence in human liver-chimeric mice. Cell Host & Microbe. 17: 526-35. PMID 25800544 DOI: 10.1016/J.Chom.2015.02.011 |
0.844 |
|
| 2015 |
Lakshmanan V, Fishbaugher ME, Morrison B, Baldwin M, Macarulay M, Vaughan AM, Mikolajczak SA, Kappe SH. Cyclic GMP balance is critical for malaria parasite transmission from the mosquito to the mammalian host. Mbio. 6: e02330. PMID 25784701 DOI: 10.1128/mBio.02330-14 |
0.517 |
|
| 2015 |
Douglass AN, Kain HS, Abdullahi M, Arang N, Austin LS, Mikolajczak SA, Billman ZP, Hume JC, Murphy SC, Kappe SH, Kaushansky A. Host-based Prophylaxis Successfully Targets Liver Stage Malaria Parasites. Molecular Therapy : the Journal of the American Society of Gene Therapy. 23: 857-65. PMID 25648263 DOI: 10.1038/Mt.2015.18 |
0.795 |
|
| 2015 |
Kaushansky A, Austin LS, Mikolajczak SA, Lo FY, Miller JL, Douglass AN, Arang N, Vaughan AM, Gardner MJ, Kappe SH. Susceptibility to Plasmodium yoelii preerythrocytic infection in BALB/c substrains is determined at the point of hepatocyte invasion. Infection and Immunity. 83: 39-47. PMID 25312960 DOI: 10.1128/Iai.02230-14 |
0.773 |
|
| 2014 |
Sack BK, Kappe SH. A novel immune regulator links malaria and inflammatory bowel disease. The Journal of Experimental Medicine. 211: 2482. PMID 25512579 DOI: 10.1084/Jem.21113Insight1 |
0.542 |
|
| 2014 |
Talley AK, Healy SA, Finney OC, Murphy SC, Kublin J, Salas CJ, Lundebjerg S, Gilbert P, Van Voorhis WC, Whisler J, Wang R, Ockenhouse CF, Heppner DG, Kappe SH, Duffy PE. Safety and comparability of controlled human Plasmodium falciparum infection by mosquito bite in malaria-naïve subjects at a new facility for sporozoite challenge. Plos One. 9: e109654. PMID 25405724 DOI: 10.1371/Journal.Pone.0109654 |
0.534 |
|
| 2014 |
Keitany GJ, Sack B, Smithers H, Chen L, Jang IK, Sebastian L, Gupta M, Sather DN, Vignali M, Vaughan AM, Kappe SH, Wang R. Immunization of mice with live-attenuated late liver stage-arresting Plasmodium yoelii parasites generates protective antibody responses to preerythrocytic stages of malaria. Infection and Immunity. 82: 5143-53. PMID 25267837 DOI: 10.1128/Iai.02320-14 |
0.456 |
|
| 2014 |
Harupa A, Sack BK, Lakshmanan V, Arang N, Douglass AN, Oliver BG, Stuart AB, Sather DN, Lindner SE, Hybiske K, Torii M, Kappe SH. SSP3 is a novel Plasmodium yoelii sporozoite surface protein with a role in gliding motility. Infection and Immunity. 82: 4643-53. PMID 25156733 DOI: 10.1128/Iai.01800-14 |
0.688 |
|
| 2014 |
Mikolajczak SA, Lakshmanan V, Fishbaugher M, Camargo N, Harupa A, Kaushansky A, Douglass AN, Baldwin M, Healer J, O'Neill M, Phuong T, Cowman A, Kappe SH. A next-generation genetically attenuated Plasmodium falciparum parasite created by triple gene deletion. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 1707-15. PMID 24827907 DOI: 10.1038/Mt.2014.85 |
0.733 |
|
| 2014 |
Miller JL, Sack BK, Baldwin M, Vaughan AM, Kappe SH. Interferon-mediated innate immune responses against malaria parasite liver stages. Cell Reports. 7: 436-47. PMID 24703850 DOI: 10.1016/j.celrep.2014.03.018 |
0.544 |
|
| 2014 |
Austin LS, Kaushansky A, Kappe SH. Susceptibility to Plasmodium liver stage infection is altered by hepatocyte polyploidy. Cellular Microbiology. 16: 784-95. PMID 24612025 DOI: 10.1111/Cmi.12282 |
0.796 |
|
| 2014 |
Finney OC, Keitany GJ, Smithers H, Kaushansky A, Kappe S, Wang R. Immunization with genetically attenuated P. falciparum parasites induces long-lived antibodies that efficiently block hepatocyte invasion by sporozoites. Vaccine. 32: 2135-8. PMID 24582635 DOI: 10.1016/J.Vaccine.2014.02.055 |
0.734 |
|
| 2014 |
Vidadala RS, Ojo KK, Johnson SM, Zhang Z, Leonard SE, Mitra A, Choi R, Reid MC, Keyloun KR, Fox AM, Kennedy M, Silver-Brace T, Hume JC, Kappe S, Verlinde CL, et al. Development of potent and selective Plasmodium falciparum calcium-dependent protein kinase 4 (PfCDPK4) inhibitors that block the transmission of malaria to mosquitoes. European Journal of Medicinal Chemistry. 74: 562-73. PMID 24531197 DOI: 10.1016/J.Ejmech.2013.12.048 |
0.476 |
|
| 2014 |
Kaushansky A, Mikolajczak SA, Vignali M, Kappe SH. Of men in mice: the success and promise of humanized mouse models for human malaria parasite infections. Cellular Microbiology. 16: 602-11. PMID 24506682 DOI: 10.1111/Cmi.12277 |
0.73 |
|
| 2014 |
Sack BK, Miller JL, Vaughan AM, Douglass A, Kaushansky A, Mikolajczak S, Coppi A, Gonzalez-Aseguinolaza G, Tsuji M, Zavala F, Sinnis P, Kappe SH. Model for in vivo assessment of humoral protection against malaria sporozoite challenge by passive transfer of monoclonal antibodies and immune serum. Infection and Immunity. 82: 808-17. PMID 24478094 DOI: 10.1128/Iai.01249-13 |
0.767 |
|
| 2014 |
Liehl P, Zuzarte-LuÃs V, Chan J, Zillinger T, Baptista F, Carapau D, Konert M, Hanson KK, Carret C, Lassnig C, Müller M, Kalinke U, Saeed M, Chora AF, Golenbock DT, ... ... Kappe SH, et al. Host-cell sensors for Plasmodium activate innate immunity against liver-stage infection. Nature Medicine. 20: 47-53. PMID 24362933 DOI: 10.1038/Nm.3424 |
0.527 |
|
| 2014 |
Lindner SE, Sartain MJ, Hayes K, Harupa A, Moritz RL, Kappe SH, Vaughan AM. Enzymes involved in plastid-targeted phosphatidic acid synthesis are essential for Plasmodium yoelii liver-stage development. Molecular Microbiology. 91: 679-93. PMID 24330260 DOI: 10.1111/Mmi.12485 |
0.686 |
|
| 2014 |
van Schaijk BC, Kumar TR, Vos MW, Richman A, van Gemert GJ, Li T, Eappen AG, Williamson KC, Morahan BJ, Fishbaugher M, Kennedy M, Camargo N, Khan SM, Janse CJ, Sim KL, ... ... Kappe SH, et al. Type II fatty acid biosynthesis is essential for Plasmodium falciparum sporozoite development in the midgut of Anopheles mosquitoes. Eukaryotic Cell. 13: 550-9. PMID 24297444 DOI: 10.1128/Ec.00264-13 |
0.479 |
|
| 2014 |
Ojo KK, Eastman RT, Vidadala R, Zhang Z, Rivas KL, Choi R, Lutz JD, Reid MC, Fox AM, Hulverson MA, Kennedy M, Isoherranen N, Kim LM, Comess KM, Kempf DJ, ... ... Kappe SH, et al. A specific inhibitor of PfCDPK4 blocks malaria transmission: chemical-genetic validation. The Journal of Infectious Diseases. 209: 275-84. PMID 24123773 DOI: 10.1093/Infdis/Jit522 |
0.361 |
|
| 2013 |
Cobbold SA, Vaughan AM, Lewis IA, Painter HJ, Camargo N, Perlman DH, Fishbaugher M, Healer J, Cowman AF, Kappe SH, Llinás M. Kinetic flux profiling elucidates two independent acetyl-CoA biosynthetic pathways in Plasmodium falciparum. The Journal of Biological Chemistry. 288: 36338-50. PMID 24163372 DOI: 10.1074/Jbc.M113.503557 |
0.396 |
|
| 2013 |
Mailu BM, Ramasamay G, Mudeppa DG, Li L, Lindner SE, Peterson MJ, DeRocher AE, Kappe SH, Rathod PK, Gardner MJ. A nondiscriminating glutamyl-tRNA synthetase in the plasmodium apicoplast: the first enzyme in an indirect aminoacylation pathway. The Journal of Biological Chemistry. 288: 32539-52. PMID 24072705 DOI: 10.1074/Jbc.M113.507467 |
0.707 |
|
| 2013 |
Spring M, Murphy J, Nielsen R, Dowler M, Bennett JW, Zarling S, Williams J, de la Vega P, Ware L, Komisar J, Polhemus M, Richie TL, Epstein J, Tamminga C, Chuang I, ... ... Kappe SH, et al. First-in-human evaluation of genetically attenuated Plasmodium falciparum sporozoites administered by bite of Anopheles mosquitoes to adult volunteers. Vaccine. 31: 4975-83. PMID 24029408 DOI: 10.1016/j.vaccine.2013.08.007 |
0.475 |
|
| 2013 |
Kaushansky A, Metzger PG, Douglass AN, Mikolajczak SA, Lakshmanan V, Kain HS, Kappe SH. Malaria parasite liver stages render host hepatocytes susceptible to mitochondria-initiated apoptosis. Cell Death & Disease. 4: e762. PMID 23928701 DOI: 10.1038/Cddis.2013.286 |
0.784 |
|
| 2013 |
Miller JL, Murray S, Vaughan AM, Harupa A, Sack B, Baldwin M, Crispe IN, Kappe SH. Quantitative bioluminescent imaging of pre-erythrocytic malaria parasite infection using luciferase-expressing Plasmodium yoelii. Plos One. 8: e60820. PMID 23593316 DOI: 10.1371/journal.pone.0060820 |
0.603 |
|
| 2013 |
Kaushansky A, Ye AS, Austin LS, Mikolajczak SA, Vaughan AM, Camargo N, Metzger PG, Douglass AN, MacBeath G, Kappe SH. Suppression of host p53 is critical for Plasmodium liver-stage infection. Cell Reports. 3: 630-7. PMID 23478020 DOI: 10.1016/J.Celrep.2013.02.010 |
0.841 |
|
| 2013 |
Pei Y, Miller JL, Lindner SE, Vaughan AM, Torii M, Kappe SH. Plasmodium yoelii inhibitor of cysteine proteases is exported to exomembrane structures and interacts with yoelipain-2 during asexual blood-stage development. Cellular Microbiology. 15: 1508-26. PMID 23421981 DOI: 10.1111/Cmi.12124 |
0.762 |
|
| 2013 |
Lindner SE, Mikolajczak SA, Vaughan AM, Moon W, Joyce BR, Sullivan WJ, Kappe SH. Perturbations of Plasmodium Puf2 expression and RNA-seq of Puf2-deficient sporozoites reveal a critical role in maintaining RNA homeostasis and parasite transmissibility. Cellular Microbiology. 15: 1266-83. PMID 23356439 DOI: 10.1111/Cmi.12116 |
0.751 |
|
| 2013 |
Lindner SE, Swearingen KE, Harupa A, Vaughan AM, Sinnis P, Moritz RL, Kappe SH. Total and putative surface proteomics of malaria parasite salivary gland sporozoites. Molecular & Cellular Proteomics : McP. 12: 1127-43. PMID 23325771 DOI: 10.1074/Mcp.M112.024505 |
0.771 |
|
| 2013 |
Vaughan AM, Kappe SH. Vaccination using radiation- or genetically attenuated live sporozoites. Methods in Molecular Biology (Clifton, N.J.). 923: 549-66. PMID 22990804 DOI: 10.1007/978-1-62703-026-7_38 |
0.405 |
|
| 2012 |
Kennedy M, Fishbaugher ME, Vaughan AM, Patrapuvich R, Boonhok R, Yimamnuaychok N, Rezakhani N, Metzger P, Ponpuak M, Sattabongkot J, Kappe SH, Hume JC, Lindner SE. A rapid and scalable density gradient purification method for Plasmodium sporozoites. Malaria Journal. 11: 421. PMID 23244590 DOI: 10.1186/1475-2875-11-421 |
0.699 |
|
| 2012 |
Nacer A, Movila A, Baer K, Mikolajczak SA, Kappe SH, Frevert U. Neuroimmunological blood brain barrier opening in experimental cerebral malaria. Plos Pathogens. 8: e1002982. PMID 23133375 DOI: 10.1371/journal.ppat.1002982 |
0.307 |
|
| 2012 |
Vaughan AM, Mikolajczak SA, Camargo N, Lakshmanan V, Kennedy M, Lindner SE, Miller JL, Hume JC, Kappe SH. A transgenic Plasmodium falciparum NF54 strain that expresses GFP-luciferase throughout the parasite life cycle. Molecular and Biochemical Parasitology. 186: 143-7. PMID 23107927 DOI: 10.1016/J.Molbiopara.2012.10.004 |
0.757 |
|
| 2012 |
Vaughan AM, Mikolajczak SA, Wilson EM, Grompe M, Kaushansky A, Camargo N, Bial J, Ploss A, Kappe SH. Complete Plasmodium falciparum liver-stage development in liver-chimeric mice. The Journal of Clinical Investigation. 122: 3618-28. PMID 22996664 DOI: 10.1172/Jci62684 |
0.795 |
|
| 2012 |
Orlov M, Vaida F, Finney OC, Smith DM, Talley AK, Wang R, Kappe SH, Deng Q, Schooley RT, Duffy PE. P. falciparum enhances HIV replication in an experimental malaria challenge system. Plos One. 7: e39000. PMID 22745697 DOI: 10.1371/Journal.Pone.0039000 |
0.378 |
|
| 2012 |
Vaughan AM, Kappe SH, Ploss A, Mikolajczak SA. Development of humanized mouse models to study human malaria parasite infection. Future Microbiology. 7: 657-65. PMID 22568719 DOI: 10.2217/Fmb.12.27 |
0.471 |
|
| 2012 |
Ojo KK, Pfander C, Mueller NR, Burstroem C, Larson ET, Bryan CM, Fox AM, Reid MC, Johnson SM, Murphy RC, Kennedy M, Mann H, Leibly DJ, Hewitt SN, Verlinde CL, ... Kappe S, et al. Transmission of malaria to mosquitoes blocked by bumped kinase inhibitors. The Journal of Clinical Investigation. 122: 2301-5. PMID 22565309 DOI: 10.1172/Jci61822 |
0.374 |
|
| 2012 |
Khan SM, Janse CJ, Kappe SH, Mikolajczak SA. Genetic engineering of attenuated malaria parasites for vaccination. Current Opinion in Biotechnology. 23: 908-16. PMID 22560204 DOI: 10.1016/j.copbio.2012.04.003 |
0.338 |
|
| 2012 |
Vaughan AM, Kappe SH. Malaria vaccine development: persistent challenges. Current Opinion in Immunology. 24: 324-31. PMID 22521906 DOI: 10.1016/j.coi.2012.03.009 |
0.314 |
|
| 2012 |
Voza T, Miller JL, Kappe SH, Sinnis P. Extrahepatic exoerythrocytic forms of rodent malaria parasites at the site of inoculation: clearance after immunization, susceptibility to primaquine, and contribution to blood-stage infection. Infection and Immunity. 80: 2158-64. PMID 22431651 DOI: 10.1128/Iai.00246-12 |
0.529 |
|
| 2012 |
Butler NS, Vaughan AM, Harty JT, Kappe SH. Whole parasite vaccination approaches for prevention of malaria infection. Trends in Immunology. 33: 247-54. PMID 22405559 DOI: 10.1016/J.It.2012.02.001 |
0.321 |
|
| 2012 |
Murphy SC, Prentice JL, Williamson K, Wallis CK, Fang FC, Fried M, Pinzon C, Wang R, Talley AK, Kappe SH, Duffy PE, Cookson BT. Real-time quantitative reverse transcription PCR for monitoring of blood-stage Plasmodium falciparum infections in malaria human challenge trials. The American Journal of Tropical Medicine and Hygiene. 86: 383-94. PMID 22403305 DOI: 10.4269/Ajtmh.2012.10-0658 |
0.418 |
|
| 2012 |
Kaushansky A, Rezakhani N, Mann H, Kappe SH. Development of a quantitative flow cytometry-based assay to assess infection by Plasmodium falciparum sporozoites. Molecular and Biochemical Parasitology. 183: 100-3. PMID 22342965 DOI: 10.1016/J.Molbiopara.2012.01.006 |
0.749 |
|
| 2012 |
Miller JL, Harupa A, Kappe SH, Mikolajczak SA. Plasmodium yoelii macrophage migration inhibitory factor is necessary for efficient liver-stage development. Infection and Immunity. 80: 1399-407. PMID 22252874 DOI: 10.1128/IAI.05861-11 |
0.582 |
|
| 2012 |
Lindner SE, Miller JL, Kappe SH. Malaria parasite pre-erythrocytic infection: preparation meets opportunity. Cellular Microbiology. 14: 316-24. PMID 22151703 DOI: 10.1111/J.1462-5822.2011.01734.X |
0.795 |
|
| 2011 |
Kaushansky A, Kappe SH. The crucial role of hepatocyte growth factor receptor during liver-stage infection is not conserved among Plasmodium species. Nature Medicine. 17: 1180-1; author reply. PMID 21988987 DOI: 10.1038/Nm.2456 |
0.719 |
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| 2011 |
Lindner SE, Llinás M, Keck JL, Kappe SH. The primase domain of PfPrex is a proteolytically matured, essential enzyme of the apicoplast. Molecular and Biochemical Parasitology. 180: 69-75. PMID 21856338 DOI: 10.1016/J.Molbiopara.2011.08.002 |
0.72 |
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| 2011 |
MacKellar DC, Vaughan AM, Aly AS, DeLeon S, Kappe SH. A systematic analysis of the early transcribed membrane protein family throughout the life cycle of Plasmodium yoelii. Cellular Microbiology. 13: 1755-67. PMID 21819513 DOI: 10.1111/J.1462-5822.2011.01656.X |
0.845 |
|
| 2011 |
Butler NS, Schmidt NW, Vaughan AM, Aly AS, Kappe SH, Harty JT. Superior antimalarial immunity after vaccination with late liver stage-arresting genetically attenuated parasites. Cell Host & Microbe. 9: 451-62. PMID 21669394 DOI: 10.1016/J.Chom.2011.05.008 |
0.401 |
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| 2011 |
Aly AS, Lindner SE, MacKellar DC, Peng X, Kappe SH. SAP1 is a critical post-transcriptional regulator of infectivity in malaria parasite sporozoite stages. Molecular Microbiology. 79: 929-39. PMID 21299648 DOI: 10.1111/J.1365-2958.2010.07497.X |
0.816 |
|
| 2010 |
Tasdemir D, Sanabria D, Lauinger IL, Tarun A, Herman R, Perozzo R, Zloh M, Kappe SH, Brun R, Carballeira NM. 2-Hexadecynoic acid inhibits plasmodial FAS-II enzymes and arrests erythrocytic and liver stage Plasmodium infections. Bioorganic & Medicinal Chemistry. 18: 7475-85. PMID 20855214 DOI: 10.1016/J.Bmc.2010.08.055 |
0.436 |
|
| 2010 |
Pei Y, Tarun AS, Vaughan AM, Herman RW, Soliman JM, Erickson-Wayman A, Kappe SH. Plasmodium pyruvate dehydrogenase activity is only essential for the parasite's progression from liver infection to blood infection. Molecular Microbiology. 75: 957-71. PMID 20487290 DOI: 10.1111/j.1365-2958.2009.07034.x |
0.464 |
|
| 2010 |
Kappe SH, Vaughan AM, Boddey JA, Cowman AF. That was then but this is now: malaria research in the time of an eradication agenda. Science (New York, N.Y.). 328: 862-6. PMID 20466924 DOI: 10.1126/science.1184785 |
0.392 |
|
| 2010 |
Mackellar DC, O'Neill MT, Aly AS, Sacci JB, Cowman AF, Kappe SH. Plasmodium falciparum PF10_0164 (ETRAMP10.3) is an essential parasitophorous vacuole and exported protein in blood stages. Eukaryotic Cell. 9: 784-94. PMID 20228203 DOI: 10.1128/Ec.00336-09 |
0.851 |
|
| 2010 |
Mikolajczak SA, Vaughan AM, Soliman JM, Kappe SH. A genetically attenuated parasite vaccine does not require liver stage persistence to elicit sterile protective immunity against sporozoite-induced malaria in mice. The Journal of Infectious Diseases. 201: 1270-1; author reply. PMID 20225958 DOI: 10.1086/651279 |
0.401 |
|
| 2010 |
Aly AS, Downie MJ, Mamoun CB, Kappe SH. Subpatent infection with nucleoside transporter 1-deficient Plasmodium blood stage parasites confers sterile protection against lethal malaria in mice. Cellular Microbiology. 12: 930-8. PMID 20088947 DOI: 10.1111/J.1462-5822.2010.01441.X |
0.498 |
|
| 2010 |
Jacobs-Lorena VY, Mikolajczak SA, Labaied M, Vaughan AM, Kappe SH. A dispensable Plasmodium locus for stable transgene expression. Molecular and Biochemical Parasitology. 171: 40-4. PMID 20045029 DOI: 10.1016/J.Molbiopara.2009.12.009 |
0.822 |
|
| 2010 |
Vaughan AM, Wang R, Kappe SH. Genetically engineered, attenuated whole-cell vaccine approaches for malaria. Human Vaccines. 6: 107-13. PMID 19838068 |
0.314 |
|
| 2009 |
Tarun AS, Vaughan AM, Kappe SH. Redefining the role of de novo fatty acid synthesis in Plasmodium parasites. Trends in Parasitology. 25: 545-50. PMID 19819758 DOI: 10.1016/j.pt.2009.09.002 |
0.39 |
|
| 2009 |
Trimnell A, Takagi A, Gupta M, Richie TL, Kappe SH, Wang R. Genetically attenuated parasite vaccines induce contact-dependent CD8+ T cell killing of Plasmodium yoelii liver stage-infected hepatocytes. Journal of Immunology (Baltimore, Md. : 1950). 183: 5870-8. PMID 19812194 DOI: 10.4049/Jimmunol.0900302 |
0.475 |
|
| 2009 |
VanBuskirk KM, O'Neill MT, De La Vega P, Maier AG, Krzych U, Williams J, Dowler MG, Sacci JB, Kangwanrangsan N, Tsuboi T, Kneteman NM, Heppner DG, Murdock BA, Mikolajczak SA, Aly AS, ... ... Kappe SH, et al. Preerythrocytic, live-attenuated Plasmodium falciparum vaccine candidates by design. Proceedings of the National Academy of Sciences of the United States of America. 106: 13004-9. PMID 19625622 DOI: 10.1073/pnas.0906387106 |
0.508 |
|
| 2009 |
Aly AS, Vaughan AM, Kappe SH. Malaria parasite development in the mosquito and infection of the mammalian host. Annual Review of Microbiology. 63: 195-221. PMID 19575563 DOI: 10.1146/annurev.micro.091208.073403 |
0.606 |
|
| 2009 |
Albuquerque SS, Carret C, Grosso AR, Tarun AS, Peng X, Kappe SH, Prudêncio M, Mota MM. Host cell transcriptional profiling during malaria liver stage infection reveals a coordinated and sequential set of biological events. Bmc Genomics. 10: 270. PMID 19534804 DOI: 10.1186/1471-2164-10-270 |
0.65 |
|
| 2009 |
Kumar KA, Baxter P, Tarun AS, Kappe SH, Nussenzweig V. Conserved protective mechanisms in radiation and genetically attenuated uis3(-) and uis4(-) Plasmodium sporozoites. Plos One. 4: e4480. PMID 19214236 DOI: 10.1371/Journal.Pone.0004480 |
0.498 |
|
| 2009 |
Vaughan AM, O'Neill MT, Tarun AS, Camargo N, Phuong TM, Aly AS, Cowman AF, Kappe SH. Type II fatty acid synthesis is essential only for malaria parasite late liver stage development. Cellular Microbiology. 11: 506-20. PMID 19068099 DOI: 10.1111/j.1462-5822.2008.01270.x |
0.494 |
|
| 2008 |
Vaughan AM, Aly AS, Kappe SH. Malaria parasite pre-erythrocytic stage infection: gliding and hiding. Cell Host & Microbe. 4: 209-18. PMID 18779047 DOI: 10.1016/j.chom.2008.08.010 |
0.611 |
|
| 2008 |
Mikolajczak SA, Silva-Rivera H, Peng X, Tarun AS, Camargo N, Jacobs-Lorena V, Daly TM, Bergman LW, de la Vega P, Williams J, Aly AS, Kappe SH. Distinct malaria parasite sporozoites reveal transcriptional changes that cause differential tissue infection competence in the mosquito vector and mammalian host. Molecular and Cellular Biology. 28: 6196-207. PMID 18710954 DOI: 10.1128/Mcb.00553-08 |
0.837 |
|
| 2008 |
Epiphanio S, Mikolajczak SA, Gonçalves LA, Pamplona A, Portugal S, Albuquerque S, Goldberg M, Rebelo S, Anderson DG, Akinc A, Vornlocher HP, Kappe SH, Soares MP, Mota MM. Heme oxygenase-1 is an anti-inflammatory host factor that promotes murine plasmodium liver infection. Cell Host & Microbe. 3: 331-8. PMID 18474360 DOI: 10.1016/J.Chom.2008.04.003 |
0.507 |
|
| 2008 |
Aly AS, Mikolajczak SA, Rivera HS, Camargo N, Jacobs-Lorena V, Labaied M, Coppens I, Kappe SH. Targeted deletion of SAP1 abolishes the expression of infectivity factors necessary for successful malaria parasite liver infection. Molecular Microbiology. 69: 152-63. PMID 18466298 DOI: 10.1111/J.1365-2958.2008.06271.X |
0.852 |
|
| 2008 |
Greenwood BM, Fidock DA, Kyle DE, Kappe SH, Alonso PL, Collins FH, Duffy PE. Malaria: progress, perils, and prospects for eradication. The Journal of Clinical Investigation. 118: 1266-76. PMID 18382739 DOI: 10.1172/Jci33996 |
0.38 |
|
| 2008 |
Mikolajczak SA, Aly AS, Dumpit RF, Vaughan AM, Kappe SH. An efficient strategy for gene targeting and phenotypic assessment in the Plasmodium yoelii rodent malaria model. Molecular and Biochemical Parasitology. 158: 213-6. PMID 18242728 DOI: 10.1016/j.molbiopara.2007.12.006 |
0.376 |
|
| 2008 |
Tarun AS, Peng X, Dumpit RF, Ogata Y, Silva-Rivera H, Camargo N, Daly TM, Bergman LW, Kappe SH. A combined transcriptome and proteome survey of malaria parasite liver stages. Proceedings of the National Academy of Sciences of the United States of America. 105: 305-10. PMID 18172196 DOI: 10.1073/Pnas.0710780104 |
0.556 |
|
| 2007 |
Baer K, Klotz C, Kappe SH, Schnieder T, Frevert U. Release of hepatic Plasmodium yoelii merozoites into the pulmonary microvasculature. Plos Pathogens. 3: e171. PMID 17997605 DOI: 10.1371/journal.ppat.0030171 |
0.482 |
|
| 2007 |
Tarun AS, Dumpit RF, Camargo N, Labaied M, Liu P, Takagi A, Wang R, Kappe SH. Protracted sterile protection with Plasmodium yoelii pre-erythrocytic genetically attenuated parasite malaria vaccines is independent of significant liver-stage persistence and is mediated by CD8+ T cells. The Journal of Infectious Diseases. 196: 608-16. PMID 17624848 DOI: 10.1086/519742 |
0.431 |
|
| 2007 |
Jobe O, Lumsden J, Mueller AK, Williams J, Silva-Rivera H, Kappe SH, Schwenk RJ, Matuschewski K, Krzych U. Genetically attenuated Plasmodium berghei liver stages induce sterile protracted protection that is mediated by major histocompatibility complex Class I-dependent interferon-gamma-producing CD8+ T cells. The Journal of Infectious Diseases. 196: 599-607. PMID 17624847 DOI: 10.1086/519743 |
0.34 |
|
| 2007 |
Labaied M, Harupa A, Dumpit RF, Coppens I, Mikolajczak SA, Kappe SH. Plasmodium yoelii sporozoites with simultaneous deletion of P52 and P36 are completely attenuated and confer sterile immunity against infection. Infection and Immunity. 75: 3758-68. PMID 17517871 DOI: 10.1128/IAI.00225-07 |
0.559 |
|
| 2007 |
Labaied M, Camargo N, Kappe SH. Depletion of the Plasmodium berghei thrombospondin-related sporozoite protein reveals a role in host cell entry by sporozoites. Molecular and Biochemical Parasitology. 153: 158-66. PMID 17418435 DOI: 10.1016/j.molbiopara.2007.03.001 |
0.604 |
|
| 2007 |
Mikolajczak SA, Jacobs-Lorena V, MacKellar DC, Camargo N, Kappe SH. L-FABP is a critical host factor for successful malaria liver stage development. International Journal For Parasitology. 37: 483-9. PMID 17303141 DOI: 10.1016/J.Ijpara.2007.01.002 |
0.796 |
|
| 2006 |
Mikolajczak SA, Kappe SH. A clash to conquer: the malaria parasite liver infection. Molecular Microbiology. 62: 1499-506. PMID 17074071 DOI: 10.1111/j.1365-2958.2006.05470.x |
0.564 |
|
| 2006 |
Cowman AF, Kappe SH. Microbiology. Malaria's stealth shuttle. Science (New York, N.Y.). 313: 1245-6. PMID 16946056 DOI: 10.1126/science.1132940 |
0.308 |
|
| 2006 |
Tarun AS, Baer K, Dumpit RF, Gray S, Lejarcegui N, Frevert U, Kappe SH. Quantitative isolation and in vivo imaging of malaria parasite liver stages. International Journal For Parasitology. 36: 1283-93. PMID 16890231 DOI: 10.1016/j.ijpara.2006.06.009 |
0.543 |
|
| 2006 |
Kappe SH, Duffy PE. Malaria liver stage culture: in vitro veritas? The American Journal of Tropical Medicine and Hygiene. 74: 706-7. PMID 16687666 |
0.381 |
|
| 2005 |
Mueller AK, Camargo N, Kaiser K, Andorfer C, Frevert U, Matuschewski K, Kappe SH. Plasmodium liver stage developmental arrest by depletion of a protein at the parasite-host interface. Proceedings of the National Academy of Sciences of the United States of America. 102: 3022-7. PMID 15699336 DOI: 10.1073/pnas.0408442102 |
0.61 |
|
| 2005 |
Mueller AK, Labaied M, Kappe SH, Matuschewski K. Genetically modified Plasmodium parasites as a protective experimental malaria vaccine. Nature. 433: 164-7. PMID 15580261 DOI: 10.1038/nature03188 |
0.577 |
|
| 2004 |
Kappe SH, Buscaglia CA, Nussenzweig V. Plasmodium sporozoite molecular cell biology. Annual Review of Cell and Developmental Biology. 20: 29-59. PMID 15473834 DOI: 10.1146/Annurev.Cellbio.20.011603.150935 |
0.629 |
|
| 2004 |
Kaiser K, Matuschewski K, Camargo N, Ross J, Kappe SH. Differential transcriptome profiling identifies Plasmodium genes encoding pre-erythrocytic stage-specific proteins. Molecular Microbiology. 51: 1221-32. PMID 14982620 DOI: 10.1046/j.1365-2958.2003.03909.x |
0.432 |
|
| 2004 |
Kappe SH, Buscaglia CA, Bergman LW, Coppens I, Nussenzweig V. Apicomplexan gliding motility and host cell invasion: overhauling the motor model. Trends in Parasitology. 20: 13-6. PMID 14700584 DOI: 10.1016/J.Pt.2003.10.011 |
0.481 |
|
| 2004 |
Kaiser K, Camargo N, Coppens I, Morrisey JM, Vaidya AB, Kappe SH. A member of a conserved Plasmodium protein family with membrane-attack complex/perforin (MACPF)-like domains localizes to the micronemes of sporozoites. Molecular and Biochemical Parasitology. 133: 15-26. PMID 14668008 DOI: 10.1016/J.Molbiopara.2003.08.009 |
0.549 |
|
| 2003 |
Kaiser K, Camargo N, Kappe SH. Transformation of sporozoites into early exoerythrocytic malaria parasites does not require host cells. The Journal of Experimental Medicine. 197: 1045-50. PMID 12707302 DOI: 10.1084/jem.20022100 |
0.545 |
|
| 2003 |
Kappe SH, Kaiser K, Matuschewski K. The Plasmodium sporozoite journey: a rite of passage. Trends in Parasitology. 19: 135-43. PMID 12643997 |
0.422 |
|
| 2003 |
Bergman LW, Kaiser K, Fujioka H, Coppens I, Daly TM, Fox S, Matuschewski K, Nussenzweig V, Kappe SH. Myosin A tail domain interacting protein (MTIP) localizes to the inner membrane complex of Plasmodium sporozoites. Journal of Cell Science. 116: 39-49. PMID 12456714 DOI: 10.1242/Jcs.00194 |
0.494 |
|
| 2002 |
Matuschewski K, Ross J, Brown SM, Kaiser K, Nussenzweig V, Kappe SH. Infectivity-associated changes in the transcriptional repertoire of the malaria parasite sporozoite stage. The Journal of Biological Chemistry. 277: 41948-53. PMID 12177071 DOI: 10.1074/Jbc.M207315200 |
0.732 |
|
| 2002 |
Blair PL, Kappe SH, Maciel JE, Balu B, Adams JH. Plasmodium falciparum MAEBL is a unique member of the ebl family. Molecular and Biochemical Parasitology. 122: 35-44. PMID 12076768 DOI: 10.1016/S0166-6851(02)00067-1 |
0.787 |
|
| 1999 |
Kappe S, Bruderer T, Gantt S, Fujioka H, Nussenzweig V, Ménard R. Conservation of a gliding motility and cell invasion machinery in Apicomplexan parasites Journal of Cell Biology. 147: 937-943. PMID 10579715 DOI: 10.1083/Jcb.147.5.937 |
0.781 |
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