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Lothar Berg - Publications

Affiliations: 
1955 Universität Rostock, Rostock, Mecklenburg-Vorpommern, Germany 
Area:
Mathematics
Website:
https://cpr.uni-rostock.de/resolve/id/cpr_person_00001546
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67 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Forconi CS, Mulama DH, Saikumar Lakshmi P, Foley J, Otieno JA, Kurtis JD, Berg LJ, Ong'echa JM, Münz C, Moormann AM. Interplay between IL-10, IFN-γ, IL-17A and PD-1 Expressing EBNA1-Specific CD4 and CD8 T Cell Responses in the Etiologic Pathway to Endemic Burkitt Lymphoma. Cancers. 13. PMID 34771539 DOI: 10.3390/cancers13215375  0.354
2021 Gallagher MP, Conley JM, Vangala P, Garber M, Reboldi A, Berg LJ. Hierarchy of signaling thresholds downstream of the T cell receptor and the Tec kinase ITK. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34452995 DOI: 10.1073/pnas.2025825118  0.36
2020 Conley JM, Gallagher MP, Rao A, Berg LJ. Activation of the Tec Kinase ITK Controls Graded IRF4 Expression in Response to Variations in TCR Signal Strength. Journal of Immunology (Baltimore, Md. : 1950). PMID 32493815 DOI: 10.4049/Jimmunol.1900853  0.341
2020 Cho HS, Ha S, Shin HM, Reboldi A, Hall JA, Huh JR, Usherwood EJ, Berg LJ. CD8 T Cells Require ITK-Mediated TCR Signaling for Migration to the Intestine. Immunohorizons. 4: 57-71. PMID 32034085 DOI: 10.4049/immunohorizons.1900093  0.413
2019 Conley JM, Berg LJ. TCR signaling: it's all about the numbers. Nature Immunology. PMID 31591572 DOI: 10.1038/S41590-019-0520-0  0.318
2018 Olesin E, Nayar R, Saikumar-Lakshmi P, Berg LJ. The Transcription Factor Runx2 Is Required for Long-Term Persistence of Antiviral CD8 Memory T Cells. Immunohorizons. 2: 251-261. PMID 30264035 DOI: 10.4049/immunohorizons.1800046  0.35
2018 Gallagher MP, Conley JM, Berg LJ. Peptide Antigen Concentration Modulates Digital NFAT1 Activation in Primary Mouse Naive CD8 T Cells as Measured by Flow Cytometry of Isolated Cell Nuclei. Immunohorizons. 2: 208-215. PMID 30221251 DOI: 10.4049/immunohorizons.1800032  0.373
2017 Shin HM, Kapoor VN, Kim G, Li P, Kim HR, Suresh M, Kaech SM, Wherry EJ, Selin LK, Leonard WJ, Welsh RM, Berg LJ. Transient expression of ZBTB32 in anti-viral CD8+ T cells limits the magnitude of the effector response and the generation of memory. Plos Pathogens. 13: e1006544. PMID 28827827 DOI: 10.1371/Journal.Ppat.1006544  0.354
2017 Falanga YT, Frascoli M, Kaymaz Y, Forconi C, Ong'echa JM, Bailey JA, Berg LJ, Moormann AM. High pathogen burden in childhood promotes the development of unconventional innate-like CD8+ T cells. Jci Insight. 2. PMID 28768916 DOI: 10.1172/Jci.Insight.93814  0.38
2016 Urban SL, Berg LJ, Welsh RM. Type 1 interferon licenses naïve CD8 T cells to mediate anti-viral cytotoxicity. Virology. 493: 52-9. PMID 26999026 DOI: 10.1016/J.Virol.2016.03.005  0.382
2016 Conley JM, Gallagher MP, Berg LJ. T Cells and Gene Regulation: The Switching On and Turning Up of Genes after T Cell Receptor Stimulation in CD8 T Cells. Frontiers in Immunology. 7: 76. PMID 26973653 DOI: 10.3389/Fimmu.2016.00076  0.417
2015 Nayar R, Schutten E, Jangalwe S, Durost PA, Kenney LL, Conley JM, Daniels K, Brehm MA, Welsh RM, Berg LJ. IRF4 Regulates the Ratio of T-Bet to Eomesodermin in CD8+ T Cells Responding to Persistent LCMV Infection. Plos One. 10: e0144826. PMID 26714260 DOI: 10.1371/Journal.Pone.0144826  0.396
2015 Cho HS, Shin HM, Haberstock-Debic H, Xing Y, Owens TD, Funk JO, Hill RJ, Bradshaw JM, Berg LJ. A Small Molecule Inhibitor of ITK and RLK Impairs Th1 Differentiation and Prevents Colitis Disease Progression. Journal of Immunology (Baltimore, Md. : 1950). PMID 26466958 DOI: 10.4049/Jimmunol.1501828  0.352
2015 Nayar R, Schutten E, Jangalwe S, Durost PA, Kenney LL, Conley JM, Daniels K, Brehm MA, Welsh RM, Berg LJ. IRF4 regulates the ratio of T-Bet to eomesodermin in CD8+ T cells responding to persistent LCMV infection Plos One. 10. DOI: 10.1371/journal.pone.0144826  0.355
2014 Pereira RM, Martinez GJ, Engel I, Cruz-Guilloty F, Barboza BA, Tsagaratou A, Lio CW, Berg LJ, Lee Y, Kronenberg M, Bandukwala HS, Rao A. Jarid2 is induced by TCR signalling and controls iNKT cell maturation. Nature Communications. 5: 4540. PMID 25105474 DOI: 10.1038/Ncomms5540  0.343
2014 Prince AL, Kraus Z, Carty SA, Ng C, Yin CC, Jordan MS, Schwartzberg PL, Berg LJ. Development of innate CD4+ and CD8+ T cells in Itk-deficient mice is regulated by distinct pathways. Journal of Immunology (Baltimore, Md. : 1950). 193: 688-99. PMID 24943215 DOI: 10.4049/Jimmunol.1302059  0.409
2014 Kapoor VN, Shin HM, Cho OH, Berg LJ, Kang J, Welsh RM. Regulation of tissue-dependent differences in CD8+ T cell apoptosis during viral infection. Journal of Virology. 88: 9490-503. PMID 24942579 DOI: 10.1128/Jvi.01223-14  0.347
2014 Prince AL, Watkin LB, Yin CC, Selin LK, Kang J, Schwartzberg PL, Berg LJ. Innate PLZF+CD4+ αβ T cells develop and expand in the absence of Itk. Journal of Immunology (Baltimore, Md. : 1950). 193: 673-87. PMID 24928994 DOI: 10.4049/Jimmunol.1302058  0.413
2014 Nayar R, Schutten E, Bautista B, Daniels K, Prince AL, Enos M, Brehm MA, Swain SL, Welsh RM, Berg LJ. Graded levels of IRF4 regulate CD8+ T cell differentiation and expansion, but not attrition, in response to acute virus infection. Journal of Immunology (Baltimore, Md. : 1950). 192: 5881-93. PMID 24835398 DOI: 10.4049/Jimmunol.1303187  0.374
2013 Jain N, Miu B, Jiang JK, McKinstry KK, Prince A, Swain SL, Greiner DL, Thomas CJ, Sanderson MJ, Berg LJ, Kang J. CD28 and ITK signals regulate autoreactive T cell trafficking. Nature Medicine. 19: 1632-7. PMID 24270545 DOI: 10.1038/Nm.3393  0.393
2013 Shin HM, Kapoor VN, Guan T, Kaech SM, Welsh RM, Berg LJ. Epigenetic modifications induced by Blimp-1 Regulate CD8⁺ T cell memory progression during acute virus infection. Immunity. 39: 661-75. PMID 24120360 DOI: 10.1016/J.Immuni.2013.08.032  0.329
2013 Joseph RE, Kleino I, Wales TE, Xie Q, Fulton DB, Engen JR, Berg LJ, Andreotti AH. Activation loop dynamics determine the different catalytic efficiencies of B cell- and T cell-specific tec kinases. Science Signaling. 6: ra76. PMID 23982207 DOI: 10.1126/Scisignal.2004298  0.33
2013 Yin CC, Cho OH, Sylvia KE, Narayan K, Prince AL, Evans JW, Kang J, Berg LJ. The Tec kinase ITK regulates thymic expansion, emigration, and maturation of γδ NKT cells. Journal of Immunology (Baltimore, Md. : 1950). 190: 2659-69. PMID 23378428 DOI: 10.4049/Jimmunol.1202531  0.364
2012 Nayar R, Enos M, Prince A, Shin H, Hemmers S, Jiang JK, Klein U, Thomas CJ, Berg LJ. TCR signaling via Tec kinase ITK and interferon regulatory factor 4 (IRF4) regulates CD8+ T-cell differentiation. Proceedings of the National Academy of Sciences of the United States of America. 109: E2794-802. PMID 23011795 DOI: 10.1073/Pnas.1205742109  0.431
2012 Narayan K, Sylvia KE, Malhotra N, Yin CC, Martens G, Vallerskog T, Kornfeld H, Xiong N, Cohen NR, Brenner MB, Berg LJ, Kang J. Intrathymic programming of effector fates in three molecularly distinct γδ T cell subtypes. Nature Immunology. 13: 511-8. PMID 22473038 DOI: 10.1038/Ni.2247  0.359
2011 Chang JT, Ciocca ML, Kinjyo I, Palanivel VR, McClurkin CE, Dejong CS, Mooney EC, Kim JS, Steinel NC, Oliaro J, Yin CC, Florea BI, Overkleeft HS, Berg LJ, Russell SM, et al. Asymmetric proteasome segregation as a mechanism for unequal partitioning of the transcription factor T-bet during T lymphocyte division. Immunity. 34: 492-504. PMID 21497118 DOI: 10.1016/J.Immuni.2011.03.017  0.362
2010 Marshall HD, Prince AL, Berg LJ, Welsh RM. IFN-alpha beta and self-MHC divert CD8 T cells into a distinct differentiation pathway characterized by rapid acquisition of effector functions. Journal of Immunology (Baltimore, Md. : 1950). 185: 1419-28. PMID 20592282 DOI: 10.4049/Jimmunol.1001140  0.374
2010 Andreotti AH, Schwartzberg PL, Joseph RE, Berg LJ. T-cell signaling regulated by the Tec family kinase, Itk. Cold Spring Harbor Perspectives in Biology. 2: a002287. PMID 20519342 DOI: 10.1101/Cshperspect.A002287  0.397
2009 Berg LJ. Strength of T cell receptor signaling strikes again. Immunity. 31: 529-31. PMID 19833081 DOI: 10.1016/J.Immuni.2009.09.008  0.332
2009 Shi M, Lin TH, Appell KC, Berg LJ. Cell cycle progression following naive T cell activation is independent of Jak3/common gamma-chain cytokine signals. Journal of Immunology (Baltimore, Md. : 1950). 183: 4493-501. PMID 19734221 DOI: 10.4049/Jimmunol.0804339  0.415
2009 Sacristán C, Schattgen SA, Berg LJ, Bunnell SC, Roy AL, Rosenstein Y. Characterization of a novel interaction between transcription factor TFII-I and the inducible tyrosine kinase in T cells. European Journal of Immunology. 39: 2584-95. PMID 19701889 DOI: 10.1002/Eji.200839031  0.365
2009 Felices M, Yin CC, Kosaka Y, Kang J, Berg LJ. Tec kinase Itk in gammadeltaT cells is pivotal for controlling IgE production in vivo. Proceedings of the National Academy of Sciences of the United States of America. 106: 8308-13. PMID 19416854 DOI: 10.1073/Pnas.0808459106  0.4
2009 Prince AL, Yin CC, Enos ME, Felices M, Berg LJ. The Tec kinases Itk and Rlk regulate conventional versus innate T-cell development. Immunological Reviews. 228: 115-31. PMID 19290924 DOI: 10.1111/J.1600-065X.2008.00746.X  0.435
2008 Shi M, Lin TH, Appell KC, Berg LJ. Janus-kinase-3-dependent signals induce chromatin remodeling at the Ifng locus during T helper 1 cell differentiation. Immunity. 28: 763-73. PMID 18549798 DOI: 10.1016/J.Immuni.2008.04.016  0.4
2008 Felices M, Berg LJ. The Tec kinases Itk and Rlk regulate NKT cell maturation, cytokine production, and survival. Journal of Immunology (Baltimore, Md. : 1950). 180: 3007-18. PMID 18292523 DOI: 10.4049/Jimmunol.180.5.3007  0.416
2008 Prince AL, Marshall HD, Atherly LO, Lucas JA, Felices M, Berg LJ. The role of tec kinases in CD8+ T cell memory differentiation The Faseb Journal. 22: 511-511. DOI: 10.1096/Fasebj.22.2_Supplement.511  0.316
2007 Lucas JA, Felices M, Evans JW, Berg LJ. Subtle defects in pre-TCR signaling in the absence of the Tec kinase Itk. Journal of Immunology (Baltimore, Md. : 1950). 179: 7561-7. PMID 18025201 DOI: 10.4049/Jimmunol.179.11.7561  0.41
2007 Berg LJ. Signalling through TEC kinases regulates conventional versus innate CD8(+) T-cell development. Nature Reviews. Immunology. 7: 479-85. PMID 17479128 DOI: 10.1038/Nri2091  0.417
2007 Felices M, Falk M, Kosaka Y, Berg LJ. Tec kinases in T cell and mast cell signaling. Advances in Immunology. 93: 145-84. PMID 17383541 DOI: 10.1016/S0065-2776(06)93004-1  0.337
2006 Kosaka Y, Felices M, Berg LJ. Itk and Th2 responses: action but no reaction. Trends in Immunology. 27: 453-60. PMID 16931156 DOI: 10.1016/J.It.2006.08.006  0.394
2006 Atherly LO, Lucas JA, Felices M, Yin CC, Reiner SL, Berg LJ. The Tec family tyrosine kinases Itk and Rlk regulate the development of conventional CD8+ T cells. Immunity. 25: 79-91. PMID 16860759 DOI: 10.1016/J.Immuni.2006.05.012  0.397
2006 Mayack SR, Berg LJ. Cutting edge: an alternative pathway of CD4+ T cell differentiation is induced following activation in the absence of gamma-chain-dependent cytokine signals. Journal of Immunology (Baltimore, Md. : 1950). 176: 2059-63. PMID 16455959 DOI: 10.4049/Jimmunol.176.4.2059  0.418
2006 Atherly LO, Brehm MA, Welsh RM, Berg LJ. Tec kinases Itk and Rlk are required for CD8+ T cell responses to virus infection independent of their role in CD4+ T cell help. Journal of Immunology (Baltimore, Md. : 1950). 176: 1571-81. PMID 16424186 DOI: 10.4049/Jimmunol.176.3.1571  0.415
2006 Atherly LO, Brehm MA, Welsh RM, Berg LJ. Tec kinases Itk and Rlk are required for CD8+ T cell responses to virus infection independent of their role in CD4+ T cell help. The Journal of Immunology. 176: 3842-3842. DOI: 10.4049/jimmunol.176.6.3842  0.358
2005 Li CR, Berg LJ. Itk is not essential for CD28 signaling in naive T cells. Journal of Immunology (Baltimore, Md. : 1950). 174: 4475-9. PMID 15814667 DOI: 10.4049/Jimmunol.174.8.4475  0.34
2005 Berg LJ, Finkelstein LD, Lucas JA, Schwartzberg PL. Tec family kinases in T lymphocyte development and function. Annual Review of Immunology. 23: 549-600. PMID 15771581 DOI: 10.1146/Annurev.Immunol.22.012703.104743  0.327
2004 Miller AT, Wilcox HM, Lai Z, Berg LJ. Signaling through Itk promotes T helper 2 differentiation via negative regulation of T-bet. Immunity. 21: 67-80. PMID 15345221 DOI: 10.1016/J.Immuni.2004.06.009  0.375
2003 Wilcox HM, Berg LJ. Itk phosphorylation sites are required for functional activity in primary T cells. The Journal of Biological Chemistry. 278: 37112-21. PMID 12842872 DOI: 10.1074/Jbc.M304811200  0.346
2003 Lucas JA, Miller AT, Atherly LO, Berg LJ. The role of Tec family kinases in T cell development and function. Immunological Reviews. 191: 119-38. PMID 12614356 DOI: 10.1034/J.1600-065X.2003.00029.X  0.381
2002 Lucas JA, Atherly LO, Berg LJ. The absence of Itk inhibits positive selection without changing lineage commitment. Journal of Immunology (Baltimore, Md. : 1950). 168: 6142-51. PMID 12055226 DOI: 10.4049/Jimmunol.168.12.6142  0.388
2002 Miller AT, Berg LJ. Defective Fas ligand expression and activation-induced cell death in the absence of IL-2-inducible T cell kinase. Journal of Immunology (Baltimore, Md. : 1950). 168: 2163-72. PMID 11859102 DOI: 10.4049/Jimmunol.168.5.2163  0.371
2001 Soldevila G, Castellanos C, Malissen M, Berg LJ. Analysis of the individual role of the TCRzeta chain in transgenic mice after conditional activation with chemical inducers of dimerization. Cellular Immunology. 214: 123-38. PMID 12088411 DOI: 10.1006/Cimm.2001.1892  0.394
2001 Berg LJ, Kang J. Molecular determinants of TCR expression and selection. Current Opinion in Immunology. 13: 232-41. PMID 11228418 DOI: 10.1016/S0952-7915(00)00209-0  0.35
2001 Gozalo-Sanmillan S, McNally JM, Lin MY, Chambers CA, Berg LJ. Cutting edge: Two distinct mechanisms lead to impaired T cell homeostasis in Janus kinase 3-and CTLA-4-deficient mice Journal of Immunology. 166: 727-730. PMID 11145642 DOI: 10.4049/Jimmunol.166.2.727  0.414
2000 Baird AM, Lucas JA, Berg LJ. A profound deficiency in thymic progenitor cells in mice lacking Jak3. Journal of Immunology (Baltimore, Md. : 1950). 165: 3680-8. PMID 11034372 DOI: 10.4049/Jimmunol.165.7.3680  0.351
1998 Bunnell SC, Berg LJ. The signal transduction of motion and antigen recognition: factors affecting T cell function and differentiation. Genetic Engineering. 20: 63-110. PMID 9666556 DOI: 10.1007/978-1-4899-1739-3_4  0.306
1998 Baird AM, Thomis DC, Berg LJ. T cell development and activation in Jak3-deficient mice. Journal of Leukocyte Biology. 63: 669-77. PMID 9620658 DOI: 10.1002/Jlb.63.6.669  0.324
1998 Liu KQ, Bunnell SC, Gurniak CB, Berg LJ. T cell receptor-initiated calcium release is uncoupled from capacitative calcium entry in Itk-deficient T cells. The Journal of Experimental Medicine. 187: 1721-7. PMID 9584150 DOI: 10.1084/Jem.187.10.1721  0.313
1997 Thomis DC, Berg LJ. Peripheral expression of Jak3 is required to maintain T lymphocyte function. The Journal of Experimental Medicine. 185: 197-206. PMID 9016869 DOI: 10.1084/Jem.185.2.197  0.385
1996 Yelon D, Spain LM, Lim K, Berg LJ. Alterations in CD4 dependence accompany T cell development and differentiation International Immunology. 8: 1077-1090. PMID 8757953 DOI: 10.1093/Intimm/8.7.1077  0.352
1995 Stowers L, Yelon D, Berg LJ, Chant J. Regulation of the polarization of T cells toward antigen-presenting cells by Ras-related GTPase CDC42. Proceedings of the National Academy of Sciences of the United States of America. 92: 5027-31. PMID 7761442 DOI: 10.1073/Pnas.92.11.5027  0.31
1995 Lieberman SA, Spain LM, Wang L, Berg LJ. Enhanced T cell maturation and altered lineage commitment in T cell receptor/CD4-transgenic mice Cellular Immunology. 162: 56-67. PMID 7704911 DOI: 10.1006/Cimm.1995.1051  0.352
1995 Raab M, Cai YC, Bunnell SC, Heyeck SD, Berg LJ, Rudd CE. p56Lck and p59Fyn regulate CD28 binding to phosphatidylinositol 3-kinase, growth factor receptor-bound protein GRB-2, and T cell-specific protein-tyrosine kinase ITK: implications for T-cell costimulation. Proceedings of the National Academy of Sciences of the United States of America. 92: 8891-5. PMID 7568038 DOI: 10.1073/Pnas.92.19.8891  0.319
1993 Heyeck SD, Berg LJ. Developmental regulation of a murine T-cell-specific tyrosine kinase gene, Tsk. Proceedings of the National Academy of Sciences of the United States of America. 90: 669-73. PMID 8421704 DOI: 10.1073/Pnas.90.2.669  0.376
1990 Davis MM, Groth BFDS, Berg LJ, Lin A, Devaux B, Sagerstrom C, Elliott JF, Bjorkman PJ. Chapter 13 Selection of an αβ T-Cell Antigen Receptor in Vivo and Expression in Vitro in a Soluble Form Current Topics in Membranes and Transport. 36: 155-160. DOI: 10.1016/S0070-2161(08)60175-6  0.347
1989 Berg LJ, Fazekas de St Groth B, Pullen AM, Davis MM. Phenotypic differences between alpha beta versus beta T-cell receptor transgenic mice undergoing negative selection. Nature. 340: 559-62. PMID 2528070 DOI: 10.1038/340559A0  0.303
1989 Berg LJ, Pullen AM, Fazekas de St Groth B, Mathis D, Benoist C, Davis MM. Antigen/MHC-specific T cells are preferentially exported from the thymus in the presence of their MHC ligand. Cell. 58: 1035-46. PMID 2476238 DOI: 10.1016/0092-8674(89)90502-3  0.343
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