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Carlo Rago, Ph.D. - Publications

Affiliations: 
2009 Johns Hopkins University, Baltimore, MD 
Area:
Oncology, Molecular Biology, Genetics
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32 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Yun J, Mullarky E, Lu C, Bosch KN, Kavalier A, Rivera K, Roper J, Chio II, Giannopoulou EG, Rago C, Muley A, Asara JM, Paik J, Elemento O, Chen Z, et al. Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH. Science (New York, N.Y.). PMID 26541605 DOI: 10.1126/Science.Aaa5004  0.694
2014 Ghosh S, Sur S, Yerram SR, Rago C, Bhunia AK, Hossain MZ, Paun BC, Ren YR, Iacobuzio-Donahue CA, Azad NA, Kern SE. Hypersensitivities for acetaldehyde and other agents among cancer cells null for clinically relevant Fanconi anemia genes. The American Journal of Pathology. 184: 260-70. PMID 24200853 DOI: 10.1016/J.Ajpath.2013.09.023  0.787
2014 Yun J, Kavalier A, Mullarky E, Bosch K, Roper J, Rago C, Paik J, Asara J, Gross S, Vogelstein B, Papadopoulos N, Cantley L. Abstract 2951: Vitamin C is selectively toxic to cancer cells harboring KRAS or BRAF mutations by targeting GAPDH Cancer Research. 74: 2951-2951. DOI: 10.1158/1538-7445.Am2014-2951  0.747
2013 Yun J, Kavalier A, Roper J, Gross S, Rago C, Papadopoulos N, Vogelstein B, Cantley L. Abstract C60: Vitamin C inhibits the survival and growth of colorectal cancer cells with KRAS or BRAF mutations Cancer Research. 73. DOI: 10.1158/1538-7445.Fbcr13-C60  0.72
2013 Ghosh S, Sur S, Yerram SR, Rago C, Bhunia AK, Hossain MZ, Paun BC, Ren YR, Iacobuzio-Donahue CA, Azad NA, Kern SE. Abstract 3580: Acetaldehyde and drug hypersensitivities of Fanconi anemia defects: Implications for cancer initiation, prevention, and therapy. Cancer Research. 73: 3580-3580. DOI: 10.1158/1538-7445.Am2013-3580  0.717
2012 Duncan CG, Barwick BG, Jin G, Rago C, Kapoor-Vazirani P, Powell DR, Chi JT, Bigner DD, Vertino PM, Yan H. A heterozygous IDH1R132H/WT mutation induces genome-wide alterations in DNA methylation. Genome Research. 22: 2339-55. PMID 22899282 DOI: 10.1101/Gr.132738.111  0.402
2010 Ericson K, Gan C, Cheong I, Rago C, Samuels Y, Velculescu VE, Kinzler KW, Huso DL, Vogelstein B, Papadopoulos N. Genetic inactivation of AKT1, AKT2, and PDPK1 in human colorectal cancer cells clarifies their roles in tumor growth regulation. Proceedings of the National Academy of Sciences of the United States of America. 107: 2598-603. PMID 20133737 DOI: 10.1073/Pnas.0914018107  0.769
2010 Ericson K, Gan C, Cheong I, Rago C, Samuels Y, Velculescu VE, Kinzler KW, Huso DL, Vogelstein B, Papadopoulos N. Genetic inactivation of AKT1, AKT2, and PDPK1 in human colorectal cancer cells clarifies their roles in tumor growth regulation (Proceedings of the National Academy of Sciences of the United States of America (2010) 107 (2598-2603) DOI: 10.1073/pnas.0914018107) Proceedings of the National Academy of Sciences of the United States of America. 107: 6551. DOI: 10.1073/Pnas.1002415107  0.754
2009 Yun J, Rago C, Cheong I, Pagliarini R, Angenendt P, Rajagopalan H, Schmidt K, Willson JK, Markowitz S, Zhou S, Diaz LA, Velculescu VE, Lengauer C, Kinzler KW, Vogelstein B, et al. Glucose deprivation contributes to the development of KRAS pathway mutations in tumor cells. Science (New York, N.Y.). 325: 1555-9. PMID 19661383 DOI: 10.1126/Science.1174229  0.775
2009 Sur S, Pagliarini R, Bunz F, Rago C, Diaz LA, Kinzler KW, Vogelstein B, Papadopoulos N. A panel of isogenic human cancer cells suggests a therapeutic approach for cancers with inactivated p53. Proceedings of the National Academy of Sciences of the United States of America. 106: 3964-9. PMID 19225112 DOI: 10.1073/Pnas.0813333106  0.796
2008 Hucl T, Rago C, Gallmeier E, Brody JR, Gorospe M, Kern SE. A syngeneic variance library for functional annotation of human variation: application to BRCA2. Cancer Research. 68: 5023-30. PMID 18593900 DOI: 10.1158/0008-5472.Can-07-6189  0.447
2007 Rago C, Vogelstein B, Bunz F. Genetic knockouts and knockins in human somatic cells Nature Protocols. 2: 2734-2746. PMID 18007609 DOI: 10.1038/Nprot.2007.408  0.524
2007 Rago C, Huso DL, Diehl F, Karim B, Liu G, Papadopoulos N, Samuels Y, Velculescu VE, Vogelstein B, Kinzler KW, Diaz LA. Serial assessment of human tumor burdens in mice by the analysis of circulating DNA. Cancer Research. 67: 9364-70. PMID 17909045 DOI: 10.1158/0008-5472.Can-07-0605  0.503
2006 Gallmeier E, Calhoun ES, Rago C, Brody JR, Cunningham SC, Hucl T, Gorospe M, Kohli M, Lengauer C, Kern SE. Targeted disruption of FANCC and FANCG in human cancer provides a preclinical model for specific therapeutic options. Gastroenterology. 130: 2145-54. PMID 16762635 DOI: 10.1053/J.Gastro.2006.03.016  0.516
2006 Dang DT, Chen F, Gardner LB, Cummins JM, Rago C, Bunz F, Kantsevoy SV, Dang LH. Hypoxia-inducible factor-1alpha promotes nonhypoxia-mediated proliferation in colon cancer cells and xenografts. Cancer Research. 66: 1684-936. PMID 16452228 DOI: 10.1158/0008-5472.Can-05-2887  0.716
2005 Dang DT, Chen F, Kohli M, Rago C, Cummins JM, Dang LH. Glutathione S-transferase pi1 promotes tumorigenicity in HCT116 human colon cancer cells. Cancer Research. 65: 9485-94. PMID 16230413 DOI: 10.1158/0008-5472.Can-05-1930  0.781
2005 Samuels Y, Diaz LA, Schmidt-Kittler O, Cummins JM, Delong L, Cheong I, Rago C, Huso DL, Lengauer C, Kinzler KW, Vogelstein B, Velculescu VE. Mutant PIK3CA promotes cell growth and invasion of human cancer cells. Cancer Cell. 7: 561-73. PMID 15950905 DOI: 10.1016/J.Ccr.2005.05.014  0.785
2005 Cho-Vega JH, Troncoso P, Do KA, Rago C, Wang X, Tsavachidis S, Medeiros LJ, Spurgers K, Logothetis C, McDonnell TJ. Combined laser capture microdissection and serial analysis of gene expression from human tissue samples. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 18: 577-84. PMID 15529182 DOI: 10.1038/Modpathol.3800327  0.447
2004 Cummins JM, Kohli M, Rago C, Kinzler KW, Vogelstein B, Bunz F. X-linked inhibitor of apoptosis protein (XIAP) is a nonredundant modulator of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis in human cancer cells. Cancer Research. 64: 3006-8. PMID 15126334 DOI: 10.1158/0008-5472.Can-04-0046  0.77
2004 Cummins JM, Rago C, Kohli M, Kinzler KW, Lengauer C, Vogelstein B. Tumour suppression: disruption of HAUSP gene stabilizes p53. Nature. 428: 1 p following 486. PMID 15058298 DOI: 10.1038/Nature02501  0.72
2004 Rajagopalan H, Jallepalli PV, Rago C, Velculescu VE, Kinzler KW, Vogelstein B, Lengauer C. Inactivation of hCDC4 can cause chromosomal instability Nature. 428: 77-81. PMID 14999283 DOI: 10.1038/Nature02313  0.575
2004 Kohli M, Rago C, Lengauer C, Kinzler KW, Vogelstein B. Facile methods for generating human somatic cell gene knockouts using recombinant adeno-associated viruses Nucleic Acids Research. 32: e3. PMID 14704360 DOI: 10.1093/Nar/Gnh009  0.576
2002 Saha S, Sparks AB, Rago C, Akmaev V, Wang CJ, Vogelstein B, Kinzler KW, Velculescu VE. Using the transcriptome to annotate the genome. Nature Biotechnology. 20: 508-12. PMID 11981567 DOI: 10.1038/Nbt0502-508  0.481
2002 Wang TL, Rago C, Silliman N, Ptak J, Markowitz S, Willson JK, Parmigiani G, Kinzler KW, Vogelstein B, Velculescu VE. Prevalence of somatic alterations in the colorectal cancer cell genome. Proceedings of the National Academy of Sciences of the United States of America. 99: 3076-80. PMID 11867767 DOI: 10.1073/Pnas.261714699  0.713
2001 Saha S, Bardelli A, Buckhaults P, Velculescu VE, Rago C, St Croix B, Romans KE, Choti MA, Lengauer C, Kinzler KW, Vogelstein B. A phosphatase associated with metastasis of colorectal cancer. Science (New York, N.Y.). 294: 1343-6. PMID 11598267 DOI: 10.1126/Science.1065817  0.61
2001 Hwang PM, Bunz F, Yu J, Rago C, Chan TA, Murphy MP, Kelso GF, Smith RA, Kinzler KW, Vogelstein B. Ferredoxin reductase affects p53-dependent, 5-fluorouracil-induced apoptosis in colorectal cancer cells. Nature Medicine. 7: 1111-7. PMID 11590433 DOI: 10.1038/Nm1001-1111  0.729
2001 Hwang PM, Bunz F, Yu J, Rago C, Chan TA, Murphy MP, Kelso GF, Smith RAJ, Kinzler KW, Vogelstein B. Erratum: Ferredoxin reductase affects p53-dependent, 5-fluorouracil-induced apoptosis in colorectal cancer cells (Nature Medicine (2001) 7 (1111-1117)) Nature Medicine. 7. DOI: 10.1038/Nm1101-1255A  0.714
2000 St Croix B, Rago C, Velculescu V, Traverso G, Romans KE, Montgomery E, Lal A, Riggins GJ, Lengauer C, Vogelstein B, Kinzler KW. Genes expressed in human tumor endothelium. Science (New York, N.Y.). 289: 1197-202. PMID 10947988 DOI: 10.1126/Science.289.5482.1197  0.51
2000 Hermeking H, Rago C, Schuhmacher M, Li Q, Barrett JF, Obaya AJ, O'Connell BC, Mateyak MK, Tam W, Kohlhuber F, Dang CV, Sedivy JM, Eick D, Vogelstein B, Kinzler KW. Identification of CDK4 as a target of c-MYC. Proceedings of the National Academy of Sciences of the United States of America. 97: 2229-34. PMID 10688915 DOI: 10.1073/Pnas.050586197  0.525
1999 Yu J, Zhang L, Hwang PM, Rago C, Kinzler KW, Vogelstein B. Identification and classification of p53-regulated genes. Proceedings of the National Academy of Sciences of the United States of America. 96: 14517-22. PMID 10588737 DOI: 10.1073/Pnas.96.25.14517  0.608
1999 Velculescu VE, Madden SL, Zhang L, Lash AE, Yu J, Rago C, Lal A, Wang CJ, Beaudry GA, Ciriello KM, Cook BP, Dufault MR, Ferguson AT, Gao Y, He TC, et al. Analysis of human transcriptomes. Nature Genetics. 23: 387-8. PMID 10581018 DOI: 10.1038/70487  0.388
1998 He TC, Sparks AB, Rago C, Hermeking H, Zawel L, Da Costa LT, Morin PJ, Vogelstein B, Kinzler KW. Identification of c-MYC as a target of the APC pathway Science. 281: 1509-1512. PMID 9727977 DOI: 10.1126/Science.281.5382.1509  0.589
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