Dong Shen, Ph.D. - Publications

Affiliations: 
2009 Johns Hopkins University, Baltimore, MD 
Area:
Genetics, Oncology

43 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Zhu J, Liu Z, Liang X, Wang L, Wu D, Mao W, Shen D. A Pan-Cancer Study of KMT2 Family as Therapeutic Targets in Cancer. Journal of Oncology. 2022: 3982226. PMID 35058979 DOI: 10.1155/2022/3982226  0.393
2021 Shen D, Zhang J, Yuan K, Zhao J, Zhao Z, Cui L, Zhang Y, Wang G, Cai S, Bai Y, Li W, Huang X. Landscape of IDH1/2 mutations in Chinese patients with solid tumors: A pan-cancer analysis. Molecular Genetics & Genomic Medicine. e1697. PMID 34145795 DOI: 10.1002/mgg3.1697  0.439
2021 He SY, Lin QF, Chen J, Yu GP, Zhang JL, Shen D. Efficacy of afatinib in a patient with rare EGFR (G724S/R776H) mutations and amplification in lung adenocarcinoma: A case report. World Journal of Clinical Cases. 9: 1329-1335. PMID 33644199 DOI: 10.12998/wjcc.v9.i6.1329  0.416
2018 Chen C, Shen D, Li J, Sun Y, Wang J. TTF-1 and EGFR expression are related to EGFR mutation in lung adenocarcinoma. International Journal of Clinical and Experimental Pathology. 11: 4650-4656. PMID 31949865  0.303
2016 Miller CA, Gindin Y, Lu C, Griffith OL, Griffith M, Shen D, Hoog J, Li T, Larson DE, Watson M, Davies SR, Hunt K, Suman VJ, Snider J, Walsh T, et al. Aromatase inhibition remodels the clonal architecture of estrogen-receptor-positive breast cancers. Nature Communications. 7: 12498. PMID 27502118 DOI: 10.1038/Ncomms12498  0.467
2016 Jiang L, Huang J, Higgs BW, Hu Z, Xiao Z, Yao X, Conley S, Zhong H, Liu Z, Brohawn P, Shen D, Wu S, Ge X, Jiang Y, Zhao Y, et al. Genomic Landscape Survey Identifies SRSF1 as a Key Oncodriver in Small Cell Lung Cancer. Plos Genetics. 12: e1005895. PMID 27093186 DOI: 10.1371/journal.pgen.1005895  0.366
2015 Churpek JE, Pyrtel K, Kanchi KL, Shao J, Koboldt D, Miller CA, Shen D, Fulton R, O'Laughlin M, Fronick C, Pusic I, Uy GL, Braunstein EM, Levis M, Ross J, et al. Genomic analysis of germline and somatic variants in familial myelodysplasia/acute myeloid leukemia. Blood. PMID 26492932 DOI: 10.1182/Blood-2015-04-641100  0.497
2015 Klco JM, Miller CA, Griffith M, Petti A, Spencer DH, Ketkar-Kulkarni S, Wartman LD, Christopher M, Lamprecht TL, Helton NM, Duncavage EJ, Payton JE, Baty J, Heath SE, Griffith OL, ... Shen D, et al. Association Between Mutation Clearance After Induction Therapy and Outcomes in Acute Myeloid Leukemia. Jama. 314: 811-22. PMID 26305651 DOI: 10.1001/Jama.2015.9643  0.326
2015 Wong TN, Ramsingh G, Young AL, Miller CA, Touma W, Welch JS, Lamprecht TL, Shen D, Hundal J, Fulton RS, Heath S, Baty JD, Klco JM, Ding L, Mardis ER, et al. Role of TP53 mutations in the origin and evolution of therapy-related acute myeloid leukaemia. Nature. 518: 552-5. PMID 25487151 DOI: 10.1038/Nature13968  0.451
2015 Klco JM, Miller CA, Griffith M, Petti A, Spencer DH, Ketkar-Kulkarni S, Wartman LD, Christopher M, Lamprecht TL, Payton JE, Baty J, Heath SE, Griffith OL, Shen D, Hundal J, et al. Abstract PR11: Genomic approaches for risk assessment in acute myeloid leukemia Cancer Research. 75. DOI: 10.1158/1538-7445.Transcagen-Pr11  0.423
2015 Klco JM, Miller CA, Griffith M, Petti A, Spencer DH, Ketkar-Kulkarni S, Wartman LD, Christopher M, Lamprecht TL, Payton JE, Baty J, Heath SE, Griffith OL, Shen D, Hundal J, et al. Abstract PR03: Genomic approaches for risk assessment in acute myeloid leukemia Cancer Research. 75. DOI: 10.1158/1538-7445.Compsysbio-Pr03  0.43
2015 Miller CA, Gindin Y, Lu C, Griffith O, Griffith M, Shen D, Hoog J, Watson M, Davies SR, Hunt K, Snider JE, DeSchryver K, Wilson RK, Ellis MJ, Mardis E. Abstract 959: Aromatase inhibition shapes the clonal architecture of estrogen receptor-positive breast cancers Cancer Research. 75: 959-959. DOI: 10.1158/1538-7445.Am2015-959  0.332
2013 Li S, Shen D, Shao J, Crowder R, Liu W, Prat A, He X, Liu S, Hoog J, Lu C, Ding L, Griffith OL, Miller C, Larson D, Fulton RS, et al. Endocrine-therapy-resistant ESR1 variants revealed by genomic characterization of breast-cancer-derived xenografts. Cell Reports. 4: 1116-30. PMID 24055055 DOI: 10.1016/J.Celrep.2013.08.022  0.478
2013 Walter MJ, Shen D, Shao J, Ding L, White BS, Kandoth C, Miller CA, Niu B, McLellan MD, Dees ND, Fulton R, Elliot K, Heath S, Grillot M, Westervelt P, et al. Clonal diversity of recurrently mutated genes in myelodysplastic syndromes. Leukemia. 27: 1275-82. PMID 23443460 DOI: 10.1038/Leu.2013.58  0.564
2013 Bose R, Kavuri SM, Searleman AC, Shen W, Shen D, Koboldt DC, Monsey J, Goel N, Aronson AB, Li S, Ma CX, Ding L, Mardis ER, Ellis MJ. Activating HER2 mutations in HER2 gene amplification negative breast cancer. Cancer Discovery. 3: 224-37. PMID 23220880 DOI: 10.1158/2159-8290.Cd-12-0349  0.583
2013 Neal Wong T, Ramsingh G, Young A, Shen D, Miller C, Lamprecht T, Heath S, Fulton RS, Mardis ER, Ding L, Westervelt P, Welch J, Walter MJ, Graubert T, DiPersio JF, et al. The Role Of Early TP53 Mutations On The Evolution Of Therapy-Related AML Blood. 122: 5-5. DOI: 10.1182/Blood.V122.21.5.5  0.488
2013 Ellis MJ, Li S, Shen D, Ding L, Crowder R, Shao J, Goncalves R, Tao Y, Luo J, Prat A, Liu W, Gonzalez-Angulo AM, Liu S, McMichael JF, Miller C, et al. Abstract LB-265: Patient-derived xenografts from advanced luminal-type breast cancer: insights into endocrine therapy resistance. Cancer Research. 73. DOI: 10.1158/1538-7445.Am2013-Lb-265  0.422
2013 Li S, Shen D, Li D, Yu T, Luo J, Hoog J, McMichael J, Miller C, Larson D, Bose R, Fulton B, Wilson R, Perou C, Mardis E, Ellis M. Abstract LB-236: Patient derived xenografts as high-fidelity genomic models for advanced breast cancer. Cancer Research. 73. DOI: 10.1158/1538-7445.Am2013-Lb-236  0.467
2012 Ellis MJ, Ding L, Shen D, Luo J, Suman VJ, Wallis JW, Van Tine BA, Hoog J, Goiffon RJ, Goldstein TC, Ng S, Lin L, Crowder R, Snider J, Ballman K, et al. Whole-genome analysis informs breast cancer response to aromatase inhibition. Nature. 486: 353-60. PMID 22722193 DOI: 10.1038/Nature11143  0.571
2012 Walter MJ, Shen D, Ding L, Shao J, Koboldt DC, Chen K, Larson DE, McLellan MD, Dooling D, Abbott R, Fulton R, Magrini V, Schmidt H, Kalicki-Veizer J, O'Laughlin M, et al. Clonal architecture of secondary acute myeloid leukemia. The New England Journal of Medicine. 366: 1090-8. PMID 22417201 DOI: 10.1056/Nejmoa1106968  0.502
2012 Koboldt DC, Zhang Q, Larson DE, Shen D, McLellan MD, Lin L, Miller CA, Mardis ER, Ding L, Wilson RK. VarScan 2: somatic mutation and copy number alteration discovery in cancer by exome sequencing. Genome Research. 22: 568-76. PMID 22300766 DOI: 10.1101/Gr.129684.111  0.554
2012 Ding L, Ley TJ, Larson DE, Miller CA, Koboldt DC, Welch JS, Ritchey JK, Young MA, Lamprecht T, McLellan MD, McMichael JF, Wallis JW, Lu C, Shen D, Harris CC, et al. Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing. Nature. 481: 506-10. PMID 22237025 DOI: 10.1038/Nature10738  0.523
2012 Graubert TA, Shen D, Ding L, Okeyo-Owuor T, Lunn CL, Shao J, Krysiak K, Harris CC, Koboldt DC, Larson DE, McLellan MD, Dooling DJ, Abbott RM, Fulton RS, Schmidt H, et al. Recurrent mutations in the U2AF1 splicing factor in myelodysplastic syndromes. Nature Genetics. 44: 53-7. PMID 22158538 DOI: 10.1038/Ng.1031  0.515
2012 Ellis MJ, Ding L, Shen D, Luo J, Suman VJ, Goiffon RJ, Wallis JW, Goldstein TC, Chen K, Allred DC, Leitch AM, Olson JA, Ota DM, Watson M, Piwnica-Worms D, et al. Whole genome sequencing to characterize luminal-type breast cancer. Journal of Clinical Oncology. 30: 503-503. DOI: 10.1200/Jco.2012.30.15_Suppl.503  0.577
2012 Ramsingh G, Shen D, Lamprecht T, Heath S, Fulton RS, Mardis ER, Ding L, Westervelt P, Welch JS, Walter MJ, Graubert T, DiPersio JF, Ley TJ, Wilson RK, Link DC. Whole Genome Sequencing of Therapy-Related Acute Myeloid Leukemia Blood. 120: 784-784. DOI: 10.1182/Blood.V120.21.784.784  0.496
2012 Tomasson MH, Shen D, Hucthagowder V, Schierding W, Mullins CD, Fiala M, Hall IM, Wallis J, Fulton RS, Fulton LA, Kulkarni S, Mardis ER, Wilson RK, Ley TJ, DiPersio JF, et al. Whole Genome Sequencing Reveals Novel Recurring Somatic Mutations Affecting HUWE1 and DIAPH2 Genes in Multiple Myeloma Blood. 120: 320-320. DOI: 10.1182/Blood.V120.21.320.320  0.551
2012 Ellis MJ, Li D, Shen D, Luo J, Suman VJ, Wallis JW, Tine BAV, Hoog J, Crowder RJ, Snider JE, Ballman K, Chen K, Koboldt DC, Schierding WS, McMichael JF, et al. Abstract LB-423: Whole genome comparisons of pre- and post- aromatase inhibitor treatment in estrogen receptor positive breast cancer Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-423  0.501
2012 Bose R, Kavuri S, Searleman A, Shen W, Shen D, Koboldt D, Monsey J, Li S, Ding L, Mardis E, Ellis M. Abstract S5-6: Activating HER2 mutations in HER2 gene amplification negative breast cancers. Cancer Research. 72. DOI: 10.1158/0008-5472.Sabcs12-S5-6  0.59
2011 Bell D, Berchuck A, Birrer M, Chien J, Cramer DW, Dao F, Dhir R, Disaia P, Gabra H, Glenn P, Godwin AK, Gross J, Hartmann L, Huang M, Huntsman DG, ... ... Shen D, et al. Integrated genomic analyses of ovarian carcinoma Nature. 474: 609-615. PMID 21720365 DOI: 10.1038/Nature10166  0.444
2011 Link DC, Schuettpelz LG, Shen D, Wang J, Walter MJ, Kulkarni S, Payton JE, Ivanovich J, Goodfellow PJ, Le Beau M, Koboldt DC, Dooling DJ, Fulton RS, Bender RH, Fulton LL, et al. Identification of a novel TP53 cancer susceptibility mutation through whole-genome sequencing of a patient with therapy-related AML. Jama. 305: 1568-76. PMID 21505135 DOI: 10.1001/Jama.2011.473  0.566
2011 Walter MJ, Ding L, Shen D, Shao J, Grillot M, McLellan M, Fulton R, Schmidt H, Kalicki-Veizer J, O'Laughlin M, Kandoth C, Baty J, Westervelt P, Dipersio JF, Mardis ER, et al. Recurrent DNMT3A mutations in patients with myelodysplastic syndromes Leukemia. 25: 1153-1158. PMID 21415852 DOI: 10.1182/Blood.V116.21.608.608  0.511
2011 Ellis MJ, Ding L, Shen D, Wallis J, Suman V, Luo J, Tao Y, Hoog J, Davies S, Lin L, Perou C, Tine BV, Bose R, Chang LW, Chen K, et al. Abstract LB-87: Analysis of luminal-type breast cancer by massively parallel sequencing Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Lb-87  0.506
2010 Ding L, Ellis MJ, Li S, Larson DE, Chen K, Wallis JW, Harris CC, McLellan MD, Fulton RS, Fulton LL, Abbott RM, Hoog J, Dooling DJ, Koboldt DC, Schmidt H, ... ... Shen D, et al. Genome remodelling in a basal-like breast cancer metastasis and xenograft. Nature. 464: 999-1005. PMID 20393555 DOI: 10.1038/Nature08989  0.438
2010 Walter MJ, Shen D, Shao J, Ding L, Grillot M, McLellan M, Fulton R, Schmidt H, Kalicki-Veizer J, Michelle O, Westervelt P, DiPersio JF, Mardis ER, Wilson R, Ley TJ, et al. Recurrent DNMT3A Mutations In Patients with Myelodysplastic Syndrome Blood. 116: 608-608. DOI: 10.1182/blood.v116.21.608.608  0.449
2010 Schuettpelz L, Link DC, Shen D, Walter MJ, Koboldt DC, Dooling DJ, Fulton RS, Schmidt H, Maupin R, O'Laughlin M, Chen K, McLellan MD, Kulkarni S, Ivanovich J, Lebeau M, et al. DNA Sequence of the Cancer Genome of a Patient with Therapy-Related Acute Myeloid Leukemia Blood. 116: 580-580. DOI: 10.1182/Blood.V116.21.580.580  0.531
2010 Walter MJ, Shen D, Ding L, Shao J, Witowski S, Chen K, Koboldt DC, Dooling DJ, Maupin R, Fulton RS, Schmidt H, O'Laughlin M, McLellan MD, Frater J, Westervelt P, et al. Detection of Novel Mutations In MDS/AML by Whole Genome Sequencing Blood. 116: 299-299. DOI: 10.1182/Blood.V116.21.299.299  0.542
2010 Mardis E, Ding L, Shen D, Wallis J, Chen K, Watson M, Hoog J, Ellis M, Rk W. Abstract ES7-1: Next Generation Sequencing for the Clinician: A Breast Cancer Study Cancer Research. 70. DOI: 10.1158/0008-5472.Sabcs10-Es7-1  0.43
2008 Barber TD, McManus K, Yuen KW, Reis M, Parmigiani G, Shen D, Barrett I, Nouhi Y, Spencer F, Markowitz S, Velculescu VE, Kinzler KW, Vogelstein B, Lengauer C, Hieter P. Chromatid cohesion defects may underlie chromosome instability in human colorectal cancers. Proceedings of the National Academy of Sciences of the United States of America. 105: 3443-8. PMID 18299561 DOI: 10.1073/Pnas.0712384105  0.665
2007 Wood LD, Parsons DW, Jones S, Lin J, Sjöblom T, Leary RJ, Shen D, Boca SM, Barber T, Ptak J, Silliman N, Szabo S, Dezso Z, Ustyanksky V, Nikolskaya T, et al. The genomic landscapes of human breast and colorectal cancers. Science (New York, N.Y.). 318: 1108-13. PMID 17932254 DOI: 10.1126/science.1145720  0.729
2005 Diehl F, Li M, Dressman D, He Y, Shen D, Szabo S, Diaz LA, Goodman SN, David KA, Juhl H, Kinzler KW, Vogelstein B. Detection and quantification of mutations in the plasma of patients with colorectal tumors. Proceedings of the National Academy of Sciences of the United States of America. 102: 16368-73. PMID 16258065 DOI: 10.1073/Pnas.0507904102  0.563
2004 van der Heijden MS, Brody JR, Gallmeier E, Cunningham SC, Dezentje DA, Shen D, Hruban RH, Kern SE. Functional defects in the fanconi anemia pathway in pancreatic cancer cells. The American Journal of Pathology. 165: 651-7. PMID 15277238 DOI: 10.1016/S0002-9440(10)63329-9  0.35
2004 Wang Z, Shen D, Parsons DW, Bardelli A, Sager J, Szabo S, Ptak J, Silliman N, Peters BA, van der Heijden MS, Parmigiani G, Yan H, Wang TL, Riggins G, Powell SM, et al. Mutational analysis of the tyrosine phosphatome in colorectal cancers. Science (New York, N.Y.). 304: 1164-6. PMID 15155950 DOI: 10.1126/Science.1096096  0.709
2004 Wang Z, Cummins JM, Shen D, Cahill DP, Jallepalli PV, Wang TL, Parsons DW, Traverso G, Awad M, Silliman N, Ptak J, Szabo S, Willson JK, Markowitz SD, Goldberg ML, et al. Three classes of genes mutated in colorectal cancers with chromosomal instability. Cancer Research. 64: 2998-3001. PMID 15126332 DOI: 10.1158/0008-5472.Can-04-0587  0.677
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