Year |
Citation |
Score |
2022 |
Kinney WD, Haar L, Lawrence DS. Lights, Camera, PAKtion: Design and Engineering of a Subcellular Targeting Optogenetic PAK1 Kinase and Sensor. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 35553711 DOI: 10.1096/fasebj.2022.36.S1.R3679 |
0.321 |
|
2021 |
Zywot EM, Orlova N, Ding S, Rampersad RR, Rabjohns EM, Wickenheisser VA, Wang Q, Welfare JG, Haar L, Eudy AM, Tarrant TK, Lawrence DS. Light-Triggered Drug Release from Red Blood Cells Suppresses Arthritic Inflammation. Advanced Therapeutics. 5. PMID 35528736 DOI: 10.1002/adtp.202100159 |
0.448 |
|
2021 |
Anttila MM, Vickerman BM, Wang Q, Lawrence DS, Allbritton NL. Photoactivatable Reporter to Perform Multiplexed and Temporally Controlled Measurements of Kinase and Protease Activity in Single Cells. Analytical Chemistry. PMID 34865468 DOI: 10.1021/acs.analchem.1c04225 |
0.501 |
|
2021 |
Vickerman BM, O'Banion CP, Tan X, Lawrence DS. Light-Controlled Release of Therapeutic Proteins from Red Blood Cells. Acs Central Science. 7: 93-103. PMID 33532572 DOI: 10.1021/acscentsci.0c01151 |
0.793 |
|
2019 |
Parag-Sharma K, O'Banion CP, Henry EC, Musicant AM, Cleveland JL, Lawrence DS, Amelio AL. Engineered BRET-Based Biologic Light Sources Enable Spatio-Temporal Control Over Diverse Optogenetic Systems. Acs Synthetic Biology. PMID 31834783 DOI: 10.1021/Acssynbio.9B00277 |
0.788 |
|
2019 |
Marvin CM, Ding S, White RE, Orlova N, Wang Q, Zywot EM, Vickerman BM, Harr L, Tarrant TK, Dayton PA, Lawrence DS. On Command Drug Delivery via Cell-Conveyed Phototherapeutics. Small (Weinheim An Der Bergstrasse, Germany). e1901442. PMID 31353802 DOI: 10.1002/Smll.201901442 |
0.495 |
|
2019 |
O'Banion CP, Vickerman BM, Haar L, Lawrence DS. Compartmentalized cAMP Generation by Engineered Photoactivated Adenylyl Cyclases. Cell Chemical Biology. PMID 31353320 DOI: 10.1016/J.Chembiol.2019.07.004 |
0.79 |
|
2019 |
Haar LL, Lawrence DS, Hughes RM. Optogenetic perturbation of the biochemical pathways that control cell behavior. Methods in Enzymology. 622: 309-328. PMID 31155059 DOI: 10.1016/Bs.Mie.2019.02.020 |
0.59 |
|
2019 |
Proctor A, Wang Q, Lawrence DS, Allbritton NL. Selection and optimization of enzyme reporters for chemical cytometry. Methods in Enzymology. 622: 221-248. PMID 31155054 DOI: 10.1016/Bs.Mie.2019.02.023 |
0.518 |
|
2019 |
O'Banion CP, Goswami A, Lawrence DS. Design, construction, and validation of optogenetic proteins. Methods in Enzymology. 621: 171-190. PMID 31128778 DOI: 10.1016/Bs.Mie.2019.02.019 |
0.796 |
|
2018 |
Cann ML, Herring LE, Haar L, Gilbert TSK, Goldfarb D, Richards KL, Graves LM, Lawrence DS. Dasatinib is preferentially active in the activated B-cell subtype of diffuse large B-cell lymphoma. Journal of Proteome Research. PMID 30540191 DOI: 10.1021/Acs.Jproteome.8B00841 |
0.302 |
|
2018 |
Lawrence D, O'banion CP. Optogenetics: A Primer for Chemists. Chembiochem : a European Journal of Chemical Biology. PMID 29671930 DOI: 10.1002/Cbic.201800013 |
0.769 |
|
2018 |
Ding S, O'Banion CP, Welfare JG, Lawrence DS. Cellular Cyborgs: On the Precipice of a Drug Delivery Revolution. Cell Chemical Biology. PMID 29628434 DOI: 10.1016/J.Chembiol.2018.03.003 |
0.765 |
|
2018 |
Vickerman BM, Anttila MM, Peterson BV, Allbritton NL, Lawrence DS. Design and Application of Sensors for Chemical Cytometry. Acs Chemical Biology. PMID 29376326 DOI: 10.1021/Acschembio.7B01009 |
0.327 |
|
2018 |
Tarrant TK, Marvin C, Wang Q, Serafin S, Lawrence D. Light-Mediated Delivery of Therapeutics Journal of Allergy and Clinical Immunology. 141: AB197. DOI: 10.1016/J.Jaci.2017.12.624 |
0.498 |
|
2017 |
O'Banion CP, Priestman MA, Hughes RM, Herring LE, Capuzzi SJ, Lawrence DS. Design and Profiling of a Subcellular Targeted Optogenetic cAMP-Dependent Protein Kinase. Cell Chemical Biology. PMID 29104065 DOI: 10.1016/J.Chembiol.2017.09.011 |
0.806 |
|
2016 |
Hughes RM, Marvin CM, Rodgers ZL, Ding S, Oien NP, Smith WJ, Lawrence DS. Phototriggered Secretion of Membrane Compartmentalized Bioactive Agents. Angewandte Chemie (International Ed. in English). PMID 27874260 DOI: 10.1002/Anie.201609731 |
0.754 |
|
2016 |
Proctor A, Zigoneanu IG, Wang Q, Sims CE, Lawrence DS, Allbritton NL. Development of a protease-resistant reporter to quantify BCR-ABL activity in intact cells. The Analyst. PMID 27704073 DOI: 10.1039/C6An01378C |
0.544 |
|
2016 |
Mainz ER, Wang Q, Lawrence DS, Allbritton NL. An Integrated Chemical Cytometry Method: Shining a Light on Akt Activity in Single Cells. Angewandte Chemie (International Ed. in English). PMID 27647713 DOI: 10.1002/Anie.201606914 |
0.563 |
|
2016 |
Rodgers ZL, Shell TA, Brugh AM, Nowotarski HL, Forbes MD, Lawrence DS. Fluorophore Assisted Photolysis of Thiolato-Cob(III)alamins. Inorganic Chemistry. PMID 26848595 DOI: 10.1021/Acs.Inorgchem.5B02036 |
0.75 |
|
2015 |
O'Banion CP, Nguyen LT, Wang Q, Priestman MA, Holly SP, Parise LV, Lawrence DS. The Plasma Membrane as a Reservoir, Protective Shield, and Light-Triggered Launch Pad for Peptide Therapeutics. Angewandte Chemie (International Ed. in English). PMID 26636264 DOI: 10.1002/Anie.201508767 |
0.777 |
|
2015 |
Turner AH, Lebhar MS, Proctor A, Wang Q, Lawrence DS, Allbritton NL. RATIONAL DESIGN OF A DEPHOSPHORYLATION-RESISTANT REPORTER ENABLES SINGLE-CELL MEASUREMENT OF TYROSINE KINASE ACTIVITY. Acs Chemical Biology. PMID 26587880 DOI: 10.1021/Acschembio.5B00667 |
0.541 |
|
2015 |
Shell TA, Lawrence DS. Vitamin B12: A Tunable, Long Wavelength, Light-Responsive Platform for Launching Therapeutic Agents. Accounts of Chemical Research. PMID 26479305 DOI: 10.1021/Acs.Accounts.5B00331 |
0.787 |
|
2015 |
Hughes RM, Freeman DJ, Lamb KN, Pollet RM, Smith WJ, Lawrence DS. Optogenetic Apoptosis: Light-Triggered Cell Death. Angewandte Chemie (International Ed. in English). 54: 12064-8. PMID 26418181 DOI: 10.1002/Anie.201506346 |
0.492 |
|
2015 |
Rodgers ZL, Hughes RM, Doherty LM, Shell JR, Molesky BP, Brugh AM, Forbes MD, Moran AM, Lawrence DS. B(12)-mediated, long wavelength photopolymerization of hydrogels. Journal of the American Chemical Society. 137: 3372-8. PMID 25697508 DOI: 10.1021/Jacs.5B00182 |
0.765 |
|
2015 |
Priestman MA, Wang Q, Jernigan FE, Chowdhury R, Schmidt M, Lawrence DS. Multicolor monitoring of the proteasome's catalytic signature. Acs Chemical Biology. 10: 433-40. PMID 25347733 DOI: 10.1021/Cb5007322 |
0.79 |
|
2014 |
Hughes RM, Lawrence DS. Optogenetic engineering: light-directed cell motility. Angewandte Chemie (International Ed. in English). 53: 10904-7. PMID 25156888 DOI: 10.1002/Anie.201404198 |
0.542 |
|
2014 |
Smith WJ, Oien NP, Hughes RM, Marvin CM, Rodgers ZL, Lee J, Lawrence DS. Cell-mediated assembly of phototherapeutics. Angewandte Chemie (International Ed. in English). 53: 10945-8. PMID 25154925 DOI: 10.1002/Anie.201406216 |
0.768 |
|
2014 |
Proctor A, Herrera-Loeza SG, Wang Q, Lawrence DS, Yeh JJ, Allbritton NL. Measurement of protein kinase B activity in single primary human pancreatic cancer cells. Analytical Chemistry. 86: 4573-80. PMID 24716819 DOI: 10.1021/Ac500616Q |
0.493 |
|
2014 |
Oien NP, Nguyen LT, Jernigan FE, Priestman MA, Lawrence DS. Long-wavelength fluorescent reporters for monitoring protein kinase activity. Angewandte Chemie (International Ed. in English). 53: 3975-8. PMID 24604833 DOI: 10.1002/Anie.201309691 |
0.78 |
|
2014 |
Shell TA, Shell JR, Rodgers ZL, Lawrence DS. Tunable visible and near-IR photoactivation of light-responsive compounds by using fluorophores as light-capturing antennas. Angewandte Chemie (International Ed. in English). 53: 875-8. PMID 24285381 DOI: 10.1002/Anie.201308816 |
0.758 |
|
2013 |
Jernigan FE, Lawrence DS. A broad spectrum dark quencher: construction of multiple colour protease and photolytic sensors. Chemical Communications (Cambridge, England). 49: 6728-30. PMID 23778327 DOI: 10.1039/C3Cc42628A |
0.74 |
|
2013 |
Phillips RM, Bair E, Lawrence DS, Sims CE, Allbritton NL. Measurement of protein tyrosine phosphatase activity in single cells by capillary electrophoresis. Analytical Chemistry. 85: 6136-42. PMID 23682679 DOI: 10.1021/Ac401106E |
0.306 |
|
2013 |
Shell JR, Lawrence DS. Probes of the mitochondrial cAMP-dependent protein kinase. Biochimica Et Biophysica Acta. 1834: 1359-63. PMID 23410952 DOI: 10.1016/J.Bbapap.2013.02.002 |
0.79 |
|
2013 |
Wang Q, Priestman MA, Lawrence DS. Monitoring of protein arginine deiminase activity by using fluorescence quenching: multicolor visualization of citrullination. Angewandte Chemie (International Ed. in English). 52: 2323-5. PMID 23339123 DOI: 10.1002/Anie.201208464 |
0.543 |
|
2013 |
Phillips RM, Lawrence DS, Sims CE, Allbritton NL. Abstract 4128: A novel approach to the measurement of tyrosine phosphorylation dynamics in intact single cells using capillary electrophoresis. Cancer Research. 73: 4128-4128. DOI: 10.1158/1538-7445.Am2013-4128 |
0.362 |
|
2012 |
Xu W, Allbritton N, Lawrence DS. SRC kinase regulation in progressively invasive cancer. Plos One. 7: e48867. PMID 23145001 DOI: 10.1371/Journal.Pone.0048867 |
0.347 |
|
2012 |
Zhang S, Chen L, Lawrence DS, Zhang ZY. A combinatorial strategy for the acquisition of potent and specific protein tyrosine phosphatase inhibitors. Methods in Molecular Biology (Clifton, N.J.). 928: 53-65. PMID 22956133 DOI: 10.1007/978-1-62703-008-3_5 |
0.374 |
|
2012 |
Proctor A, Wang Q, Lawrence DS, Allbritton NL. Development of a peptidase-resistant substrate for single-cell measurement of protein kinase B activation. Analytical Chemistry. 84: 7195-202. PMID 22881604 DOI: 10.1021/Ac301489D |
0.53 |
|
2012 |
Priestman MA, Shell TA, Sun L, Lee HM, Lawrence DS. Merging of confocal and caging technologies: selective three-color communication with profluorescent reporters. Angewandte Chemie (International Ed. in English). 51: 7684-7. PMID 22740297 DOI: 10.1002/Anie.201202820 |
0.772 |
|
2012 |
Shell JR, Lawrence DS. Proteolytic regulation of the mitochondrial cAMP-dependent protein kinase. Biochemistry. 51: 2258-64. PMID 22385295 DOI: 10.1021/Bi201573K |
0.766 |
|
2012 |
Proctor A, Wang Q, Lawrence DS, Allbritton NL. Metabolism of peptide reporters in cell lysates and single cells. The Analyst. 137: 3028-38. PMID 22314840 DOI: 10.1039/C2An16162A |
0.511 |
|
2012 |
Phillips RM, Lawrence DS, Allbritton NL. Analysis of EGFR Signaling in Single Cells using Capillary Electrophoresis Biophysical Journal. 102: 666a-667a. DOI: 10.1016/J.Bpj.2011.11.3629 |
0.387 |
|
2012 |
Proctor A, Wang Q, Lawrence DS, Allbritton NL. Construction of Peptidase-Resistant Substrates for Kinases Biophysical Journal. 102: 273a. DOI: 10.1016/J.Bpj.2011.11.1503 |
0.529 |
|
2011 |
Lee HM, Xu W, Lawrence DS. Construction of a photoactivatable profluorescent enzyme via propinquity labeling. Journal of the American Chemical Society. 133: 2331-3. PMID 21302921 DOI: 10.1021/Ja108950Q |
0.624 |
|
2011 |
Shell TA, Lawrence DS. A new trick (hydroxyl radical generation) for an old vitamin (B12). Journal of the American Chemical Society. 133: 2148-50. PMID 21275391 DOI: 10.1021/Ja111585C |
0.754 |
|
2011 |
Priestman MA, Sun L, Lawrence DS. Dual wavelength photoactivation of cAMP- and cGMP-dependent protein kinase signaling pathways. Acs Chemical Biology. 6: 377-84. PMID 21218856 DOI: 10.1021/Cb100398E |
0.426 |
|
2010 |
Wang Q, Zimmerman EI, Toutchkine A, Martin TD, Graves LM, Lawrence DS. Multicolor monitoring of dysregulated protein kinases in chronic myelogenous leukemia. Acs Chemical Biology. 5: 887-95. PMID 20583816 DOI: 10.1021/Cb100099H |
0.537 |
|
2010 |
Agnes RS, Jernigan F, Shell JR, Sharma V, Lawrence DS. Suborganelle sensing of mitochondrial cAMP-dependent protein kinase activity. Journal of the American Chemical Society. 132: 6075-80. PMID 20380406 DOI: 10.1021/Ja909652Q |
0.789 |
|
2010 |
Wakata A, Lee HM, Rommel P, Toutchkine A, Schmidt M, Lawrence DS. Simultaneous fluorescent monitoring of proteasomal subunit catalysis. Journal of the American Chemical Society. 132: 1578-82. PMID 20078037 DOI: 10.1021/Ja907226N |
0.607 |
|
2010 |
Lee HM, Priestman MA, Lawrence DS. Light-mediated spatial control via photolabile fluorescently quenched peptide cassettes. Journal of the American Chemical Society. 132: 1446-7. PMID 20073458 DOI: 10.1021/Ja907427P |
0.606 |
|
2010 |
Priestman MA, Lawrence DS. Light-mediated remote control of signaling pathways. Biochimica Et Biophysica Acta. 1804: 547-58. PMID 19765679 DOI: 10.1016/J.Bbapap.2009.09.005 |
0.426 |
|
2009 |
Sharma V, Lawrence DS. Uber-responsive peptide-based sensors of signaling proteins. Angewandte Chemie (International Ed. in English). 48: 7290-2. PMID 19739174 DOI: 10.1002/Anie.200903717 |
0.355 |
|
2009 |
Zhang S, Chen L, Luo Y, Gunawan A, Lawrence DS, Zhang ZY. Acquisition of a potent and selective TC-PTP inhibitor via a stepwise fluorophore-tagged combinatorial synthesis and screening strategy. Journal of the American Chemical Society. 131: 13072-9. PMID 19737019 DOI: 10.1021/Ja903733Z |
0.354 |
|
2009 |
Lee HM, Larson DR, Lawrence DS. Illuminating the chemistry of life: design, synthesis, and applications of "caged" and related photoresponsive compounds. Acs Chemical Biology. 4: 409-27. PMID 19298086 DOI: 10.1021/Cb900036S |
0.586 |
|
2008 |
Li H, Hah JM, Lawrence DS. Light-mediated liberation of enzymatic activity: "small molecule" caged protein equivalents. Journal of the American Chemical Society. 130: 10474-5. PMID 18642802 DOI: 10.1021/Ja803395D |
0.661 |
|
2008 |
Lee JH, Kumar S, Lawrence DS. Stepwise combinatorial evolution of Akt bisubstrate inhibitors. Chembiochem : a European Journal of Chemical Biology. 9: 507-9. PMID 18224646 DOI: 10.1002/Cbic.200700583 |
0.62 |
|
2008 |
Garrett SC, Hodgson L, Rybin A, Toutchkine A, Hahn KM, Lawrence DS, Bresnick AR. A biosensor of S100A4 metastasis factor activation: inhibitor screening and cellular activation dynamics. Biochemistry. 47: 986-96. PMID 18154362 DOI: 10.1021/Bi7021624 |
0.36 |
|
2008 |
Wakata A, Cahill SM, Blumenstein M, Gunby RH, Jockusch S, Marti AA, Cimbro B, Gambacorti-Passerini C, Donella-Deana A, Pinna LA, Turro NJ, Lawrence DS. A mechanistic design principle for protein tyrosine kinase sensors: application to a validated cancer target. Organic Letters. 10: 301-4. PMID 18085786 DOI: 10.1021/Ol702675B |
0.367 |
|
2008 |
Sharma V, Wang Q, Lawrence DS. Peptide-based fluorescent sensors of protein kinase activity: design and applications. Biochimica Et Biophysica Acta. 1784: 94-9. PMID 17881302 DOI: 10.1016/J.Bbapap.2007.07.016 |
0.559 |
|
2007 |
Dai Z, Dulyaninova NG, Kumar S, Bresnick AR, Lawrence DS. Visual snapshots of intracellular kinase activity at the onset of mitosis. Chemistry & Biology. 14: 1254-60. PMID 18022564 DOI: 10.1016/J.Chembiol.2007.10.007 |
0.678 |
|
2007 |
Zhang S, Chen L, Kumar S, Wu L, Lawrence DS, Zhang ZY. An affinity-based fluorescence polarization assay for protein tyrosine phosphatases. Methods (San Diego, Calif.). 42: 261-7. PMID 17532513 DOI: 10.1016/J.Ymeth.2007.02.008 |
0.57 |
|
2007 |
Nandy SK, Agnes RS, Lawrence DS. Photochemically-activated probes of protein-protein interactions. Organic Letters. 9: 2249-52. PMID 17506572 DOI: 10.1021/Ol070238T |
0.411 |
|
2007 |
Sharma V, Agnes RS, Lawrence DS. Deep quench: an expanded dynamic range for protein kinase sensors. Journal of the American Chemical Society. 129: 2742-3. PMID 17305340 DOI: 10.1021/Ja068280R |
0.401 |
|
2007 |
Lawrence DS, Wang Q. Seeing is believing: peptide-based fluorescent sensors of protein tyrosine kinase activity. Chembiochem : a European Journal of Chemical Biology. 8: 373-8. PMID 17243187 DOI: 10.1002/Cbic.200600473 |
0.567 |
|
2006 |
Wang Q, Dai Z, Cahill SM, Blumenstein M, Lawrence DS. Light-regulated sampling of protein tyrosine kinase activity. Journal of the American Chemical Society. 128: 14016-7. PMID 17061870 DOI: 10.1021/Ja065852Z |
0.669 |
|
2006 |
Hah JM, Sharma V, Li H, Lawrence DS. Acquisition of a "Group A"-selective Src kinase inhibitor via a global targeting strategy. Journal of the American Chemical Society. 128: 5996-7. PMID 16669643 DOI: 10.1021/Ja060136I |
0.633 |
|
2006 |
Wang Q, Cahill SM, Blumenstein M, Lawrence DS. Self-reporting fluorescent substrates of protein tyrosine kinases. Journal of the American Chemical Society. 128: 1808-9. PMID 16464077 DOI: 10.1021/Ja0577692 |
0.559 |
|
2006 |
Lee H, Xie L, Luo Y, Lee SY, Lawrence DS, Wang XB, Sotgia F, Lisanti MP, Zhang ZY. Identification of phosphocaveolin-1 as a novel protein tyrosine phosphatase 1B substrate. Biochemistry. 45: 234-40. PMID 16388599 DOI: 10.1021/Bi051560J |
0.393 |
|
2005 |
Varfolomeev E, Maecker H, Sharp D, Lawrence D, Renz M, Vucic D, Ashkenazi A. Molecular determinants of kinase pathway activation by Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand. The Journal of Biological Chemistry. 280: 40599-608. PMID 16227629 DOI: 10.1074/Jbc.M509560200 |
0.324 |
|
2005 |
Lawrence DS. The preparation and in vivo applications of caged peptides and proteins. Current Opinion in Chemical Biology. 9: 570-5. PMID 16182597 DOI: 10.1016/J.Cbpa.2005.09.002 |
0.379 |
|
2005 |
Lawrence DS. Signaling protein inhibitors via the combinatorial modification of peptide scaffolds. Biochimica Et Biophysica Acta. 1754: 50-7. PMID 16172031 DOI: 10.1016/J.Bbapap.2005.07.038 |
0.381 |
|
2005 |
Li H, Lawrence DS. Acquisition of Fyn-selective SH3 domain ligands via a combinatorial library strategy. Chemistry & Biology. 12: 905-12. PMID 16125102 DOI: 10.1016/J.Chembiol.2005.06.007 |
0.332 |
|
2005 |
Wang Q, Lawrence DS. Phosphorylation-driven protein-protein interactions: a protein kinase sensing system. Journal of the American Chemical Society. 127: 7684-5. PMID 15913351 DOI: 10.1021/Ja050789J |
0.566 |
|
2005 |
Liang F, Lee SY, Liang J, Lawrence DS, Zhang ZY. The role of protein-tyrosine phosphatase 1B in integrin signaling. The Journal of Biological Chemistry. 280: 24857-63. PMID 15866871 DOI: 10.1074/Jbc.M502780200 |
0.383 |
|
2005 |
Kumar S, Liang F, Lawrence DS, Zhang ZY. Small molecule approach to studying protein tyrosine phosphatase. Methods (San Diego, Calif.). 35: 9-21. PMID 15588981 DOI: 10.1016/J.Ymeth.2004.07.003 |
0.538 |
|
2004 |
Ghosh M, Song X, Mouneimne G, Sidani M, Lawrence DS, Condeelis JS. Cofilin promotes actin polymerization and defines the direction of cell motility. Science (New York, N.Y.). 304: 743-6. PMID 15118165 DOI: 10.1126/Science.1094561 |
0.572 |
|
2004 |
Lee JH, Nandy SK, Lawrence DS. A highly potent and selective PKCalpha inhibitor generated via combinatorial modification of a peptide scaffold. Journal of the American Chemical Society. 126: 3394-5. PMID 15025445 DOI: 10.1021/Ja037300B |
0.543 |
|
2004 |
Chen CA, Yeh RH, Yan X, Lawrence DS. Biosensors of protein kinase action: from in vitro assays to living cells. Biochimica Et Biophysica Acta. 1697: 39-51. PMID 15023349 DOI: 10.1016/J.Bbapap.2003.11.012 |
0.44 |
|
2003 |
Xie L, Lee SY, Andersen JN, Waters S, Shen K, Guo XL, Moller NP, Olefsky JM, Lawrence DS, Zhang ZY. Cellular effects of small molecule PTP1B inhibitors on insulin signaling. Biochemistry. 42: 12792-804. PMID 14596593 DOI: 10.1021/Bi035238P |
0.618 |
|
2003 |
Veldhuyzen WF, Nguyen Q, McMaster G, Lawrence DS. A light-activated probe of intracellular protein kinase activity. Journal of the American Chemical Society. 125: 13358-9. PMID 14583022 DOI: 10.1021/Ja037801X |
0.418 |
|
2003 |
Liang F, Huang Z, Lee SY, Liang J, Ivanov MI, Alonso A, Bliska JB, Lawrence DS, Mustelin T, Zhang ZY. Aurintricarboxylic acid blocks in vitro and in vivo activity of YopH, an essential virulent factor of Yersinia pestis, the agent of plague. The Journal of Biological Chemistry. 278: 41734-41. PMID 12888560 DOI: 10.1074/Jbc.M307152200 |
0.353 |
|
2003 |
Lawrence DS. Chemical probes of signal-transducing proteins. Accounts of Chemical Research. 36: 401-9. PMID 12809526 DOI: 10.1021/Ar020132S |
0.417 |
|
2003 |
Shang L, Kwon YG, Nandy S, Lawrence DS, Edelman AM. Catalytic and regulatory domains of doublecortin kinase-1. Biochemistry. 42: 2185-94. PMID 12590608 DOI: 10.1021/Bi026913I |
0.37 |
|
2003 |
Sun JP, Fedorov AA, Lee SY, Guo XL, Shen K, Lawrence DS, Almo SC, Zhang ZY. Crystal structure of PTP1B complexed with a potent and selective bidentate inhibitor. The Journal of Biological Chemistry. 278: 12406-14. PMID 12547827 DOI: 10.1074/Jbc.M212491200 |
0.634 |
|
2002 |
Lin W, Albanese C, Pestell RG, Lawrence DS. Spatially discrete, light-driven protein expression. Chemistry & Biology. 9: 1347-53. PMID 12498888 DOI: 10.1016/S1074-5521(02)00288-0 |
0.465 |
|
2002 |
Guo XL, Shen K, Wang F, Lawrence DS, Zhang ZY. Probing the molecular basis for potent and selective protein-tyrosine phosphatase 1B inhibition. The Journal of Biological Chemistry. 277: 41014-22. PMID 12193602 DOI: 10.1074/Jbc.M207347200 |
0.643 |
|
2002 |
Yeh RH, Lee TR, Lawrence DS. From consensus sequence to high-affinity ligands: acquisition of signaling protein modulators. Pharmacology & Therapeutics. 93: 179-91. PMID 12191610 DOI: 10.1016/S0163-7258(02)00187-0 |
0.345 |
|
2002 |
Lin W, Lawrence DS. A strategy for the construction of caged diols using a photolabile protecting group. The Journal of Organic Chemistry. 67: 2723-6. PMID 11950329 DOI: 10.1021/Jo0163851 |
0.486 |
|
2002 |
Chen CA, Yeh RH, Lawrence DS. Design and synthesis of a fluorescent reporter of protein kinase activity. Journal of the American Chemical Society. 124: 3840-1. PMID 11942815 DOI: 10.1021/Ja017530V |
0.395 |
|
2002 |
Ghosh M, Ichetovkin I, Song X, Condeelis JS, Lawrence DS. A new strategy for caging proteins regulated by kinases. Journal of the American Chemical Society. 124: 2440-1. PMID 11890784 DOI: 10.1021/Ja017592L |
0.59 |
|
2002 |
Yeh RH, Yan X, Cammer M, Bresnick AR, Lawrence DS. Real time visualization of protein kinase activity in living cells. The Journal of Biological Chemistry. 277: 11527-32. PMID 11790790 DOI: 10.1074/Jbc.M111300200 |
0.426 |
|
2001 |
Shen K, Keng YF, Wu L, Guo XL, Lawrence DS, Zhang ZY. Acquisition of a specific and potent PTP1B inhibitor from a novel combinatorial library and screening procedure. The Journal of Biological Chemistry. 276: 47311-9. PMID 11584002 DOI: 10.1074/Jbc.M106568200 |
0.653 |
|
2001 |
Yeh RH, Lee TR, Lawrence DS. From consensus sequence peptide to high affinity ligand, a "library scan" strategy. The Journal of Biological Chemistry. 276: 12235-40. PMID 11278862 DOI: 10.1074/Jbc.M011232200 |
0.308 |
|
2001 |
Lawrence DS. Functional proteomics: large-scale analysis of protein kinase activity. Genome Biology. 2: REVIEWS1007. PMID 11182893 DOI: 10.1186/Gb-2001-2-2-Reviews1007 |
0.371 |
|
2001 |
Arancio O, Antonova I, Gambaryan S, Lohmann SM, Wood JS, Lawrence DS, Hawkins RD. Presynaptic role of cGMP-dependent protein kinase during long-lasting potentiation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 143-9. PMID 11150330 DOI: 10.1523/Jneurosci.21-01-00143.2001 |
0.32 |
|
2001 |
Profit AA, Lee TR, Niu J, Lawrence DS. Molecular rulers: an assessment of distance and spatial relationships of Src tyrosine kinase Sh2 and active site regions. The Journal of Biological Chemistry. 276: 9446-51. PMID 11118446 DOI: 10.1074/Jbc.M009262200 |
0.344 |
|
2001 |
Zhou B, Wu L, Shen K, Zhang J, Lawrence DS, Zhang ZY. Multiple regions of MAP kinase phosphatase 3 are involved in its recognition and activation by ERK2. The Journal of Biological Chemistry. 276: 6506-15. PMID 11104775 DOI: 10.1074/Jbc.M009753200 |
0.651 |
|
2000 |
Zebda N, Bernard O, Bailly M, Welti S, Lawrence DS, Condeelis JS. Phosphorylation of ADF/cofilin abolishes EGF-induced actin nucleation at the leading edge and subsequent lamellipod extension. The Journal of Cell Biology. 151: 1119-28. PMID 11086013 DOI: 10.1083/Jcb.151.5.1119 |
0.329 |
|
2000 |
Yan X, Curley K, Lawrence DS. The specificity of the protein kinase C alpha, betaII and gamma isoforms as assessed by an unnatural alcohol-appended peptide library. The Biochemical Journal. 349: 709-15. PMID 10903131 DOI: 10.1042/Bj3490709 |
0.356 |
|
2000 |
Vetter SW, Keng YF, Lawrence DS, Zhang ZY. Assessment of protein-tyrosine phosphatase 1B substrate specificity using "inverse alanine scanning". The Journal of Biological Chemistry. 275: 2265-8. PMID 10644673 DOI: 10.1074/Jbc.275.4.2265 |
0.335 |
|
1999 |
Curley K, Lawrence DS. Caged regulators of signaling pathways. Pharmacology & Therapeutics. 82: 347-54. PMID 10454211 DOI: 10.1016/S0163-7258(98)00055-2 |
0.398 |
|
1999 |
Taing M, Keng YF, Shen K, Wu L, Lawrence DS, Zhang ZY. Potent and highly selective inhibitors of the protein tyrosine phosphatase 1B. Biochemistry. 38: 3793-803. PMID 10090769 DOI: 10.1021/Bi9813781 |
0.644 |
|
1999 |
Curley K, Lawrence DS. Light-activated proteins. Current Opinion in Chemical Biology. 3: 84-8. PMID 10021410 DOI: 10.1016/S1367-5931(99)80015-5 |
0.381 |
|
1999 |
Profit AA, Lee TR, Lawrence DS. Bivalent inhibitors of protein tyrosine kinases Journal of the American Chemical Society. 121: 280-283. DOI: 10.1021/Ja983515N |
0.398 |
|
1998 |
Lawrence DS, Niu J. Protein kinase inhibitors: the tyrosine-specific protein kinases. Pharmacology & Therapeutics. 77: 81-114. PMID 9578319 DOI: 10.1016/S0163-7258(97)00052-1 |
0.392 |
|
1998 |
White RR, Kwon YG, Taing M, Lawrence DS, Edelman AM. Definition of optimal substrate recognition motifs of Ca2+-calmodulin-dependent protein kinases IV and II reveals shared and distinctive features. The Journal of Biological Chemistry. 273: 3166-72. PMID 9452427 DOI: 10.1074/Jbc.273.6.3166 |
0.345 |
|
1998 |
Wood JS, Koszelak M, Liu J, Lawrence DS. A caged protein kinase inhibitor [23] Journal of the American Chemical Society. 120: 7145-7146. DOI: 10.1021/Ja980960+ |
0.355 |
|
1997 |
Puius YA, Zhao Y, Sullivan M, Lawrence DS, Almo SC, Zhang ZY. Identification of a second aryl phosphate-binding site in protein-tyrosine phosphatase 1B: a paradigm for inhibitor design. Proceedings of the National Academy of Sciences of the United States of America. 94: 13420-5. PMID 9391040 DOI: 10.1073/Pnas.94.25.13420 |
0.302 |
|
1997 |
Pluskey S, Mahroof-Tahir M, Crans DC, Lawrence DS. Vanadium oxoanions and cAMP-dependent protein kinase: an anti-substrate inhibitor. The Biochemical Journal. 321: 333-9. PMID 9020863 DOI: 10.1042/Bj3210333 |
0.386 |
|
1997 |
Niu J, Lawrence DS. Nonphosphorylatable tyrosine surrogates. Implications for protein kinase inhibitor design. The Journal of Biological Chemistry. 272: 1493-9. PMID 8999819 DOI: 10.1074/Jbc.272.3.1493 |
0.388 |
|
1996 |
Chen L, Montserat J, Lawrence DS, Zhang ZY. VHR and PTP1 protein phosphatases exhibit remarkably different active site specificities toward low molecular weight nonpeptidic substrates Biochemistry. 35: 9349-9354. PMID 8755712 DOI: 10.1021/Bi960700+ |
0.383 |
|
1996 |
Wang C, Lee TR, Lawrence DS, Adams JA. Rate-determining steps for tyrosine phosphorylation by the kinase domain of v-fps. Biochemistry. 35: 1533-9. PMID 8634284 DOI: 10.1021/Bi952435I |
0.374 |
|
1996 |
Montserat J, Chen L, Lawrence DS, Zhang ZY. Potent low molecular weight substrates for protein-tyrosine phosphatase Journal of Biological Chemistry. 271: 7868-7872. PMID 8631832 DOI: 10.1074/Jbc.271.13.7868 |
0.361 |
|
1996 |
Yan X, Corbin JD, Francis SH, Lawrence DS. Precision targeting of protein kinases: An affinity label that inactivates the cGMP- but not the cAMP-dependent protein kinase Journal of Biological Chemistry. 271: 1845-1848. PMID 8567627 DOI: 10.1074/Jbc.271.4.1845 |
0.388 |
|
1996 |
Werner DS, Lee TR, Lawrence DS. Is protein kinase substrate efficacy a reliable barometer for successful inhibitor design? Journal of Biological Chemistry. 271: 180-185. PMID 8550556 DOI: 10.1074/Jbc.271.1.180 |
0.343 |
|
1996 |
Wood JS, Yan X, Mendelow M, Corbin JD, Francis SH, Lawrence DS. Precision substrate targeting of protein kinases: The cGMP- and cAMP-dependent protein kinases Journal of Biological Chemistry. 271: 174-179. PMID 8550555 DOI: 10.1074/Jbc.271.1.174 |
0.372 |
|
1996 |
Dunn D, Chen L, Lawrence DS, Zhang ZY. The active site specificity of the Yersinia protein-tyrosine phosphatase Journal of Biological Chemistry. 271: 168-173. PMID 8550553 DOI: 10.1074/Jbc.271.1.168 |
0.364 |
|
1996 |
Yan X, Lawrence DS, Corbin JD, Francis SH. Distinguishing between A mitogenic and two closely related nonmitogenic protein kinases Journal of the American Chemical Society. 118: 11684-11685. DOI: 10.1021/Ja963129A |
0.341 |
|
1996 |
Yan X, Lawrence DS, Corbin JD, Francis SH. Distinguishing between closely related protein kinases: A variation on the bisubstrate inhibitor theme Journal of the American Chemical Society. 118: 6321-6322. DOI: 10.1021/Ja9609213 |
0.347 |
|
1995 |
Srinivasan J, Koszelak M, Mendelow M, Kwon YG, Lawrence DS. The design of peptide-based substrates for the cdc2 protein kinase. The Biochemical Journal. 927-31. PMID 7639712 DOI: 10.1042/Bj3090927 |
0.382 |
|
1995 |
Lee TR, Till JH, Lawrence DS, Miller WT. Precision substrate targeting of protein kinases v-Abl and c-Src. The Journal of Biological Chemistry. 270: 27022-6. PMID 7592951 DOI: 10.1074/Jbc.270.45.27022 |
0.49 |
|
1995 |
Lee TR, Niu J, Lawrence DS. The extraordinary active site substrate specificity of pp60c-src: A multiple specificity protein kinase Journal of Biological Chemistry. 270: 5375-5380. PMID 7534295 DOI: 10.1074/Jbc.270.10.5375 |
0.403 |
|
1994 |
Lee TR, Niu J, Lawrence DS. Phenol kinase activity of the serine/threonine-specific cAMP-dependent protein kinase: steric and electronic effects. Biochemistry. 33: 4245-50. PMID 8155641 DOI: 10.1021/Bi00180A019 |
0.351 |
|
1994 |
Lee JC, Kwon YG, Lawrence DS, Edelman AM. A requirement of hydrophobic and basic amino acid residues for substrate recognition by Ca2+/calmodulin-dependent protein kinase Ia. Proceedings of the National Academy of Sciences of the United States of America. 91: 6413-7. PMID 8022798 DOI: 10.1073/Pnas.91.14.6413 |
0.319 |
|
1993 |
Lee TR, Mendelow M, Srinivasan J, Kwon YG, Lawrence DS. Molecular basis for the substrate specificity of a serine threonine-specific protein kinase Journal of the American Chemical Society. 115: 9888-9891. DOI: 10.1021/Ja00075A003 |
0.373 |
|
1993 |
Kwon YG, Srinivasan J, Mendelow M, Pluskey S, Lawrence DS. The cAMP-dependent protein kinase discriminates between prochiral hydroxyl groups Journal of the American Chemical Society. 115: 7527-7528. DOI: 10.1021/Ja00069A072 |
0.34 |
|
1992 |
Dick DL, Rao TVS, Sukumaran D, Lawrence DS. Molecular encapsulation: cyclodextrin-based analogs of heme-containing proteins Journal of the American Chemical Society. 114: 2664-2669. DOI: 10.1021/Ja00033A046 |
0.322 |
|
1991 |
Sukumaran DK, Prorok M, Lawrence DS. A molecular constraint that generates a cis peptide bond Journal of the American Chemical Society. 113: 706-707. DOI: 10.1021/Ja00002A067 |
0.696 |
|
1990 |
Prorok M, Lawrence DS. Multiple arginine residues contribute to the increased efficacy of peptide substrates for the cAMP-dependent protein kinase. Biochemical and Biophysical Research Communications. 165: 368-71. PMID 2590233 DOI: 10.1016/0006-291X(89)91079-6 |
0.378 |
|
1990 |
Prorok M, Lawrence DS. An affinity label of absolute peptidic origin Journal of the American Chemical Society. 112: 8626-8627. DOI: 10.1021/Ja00179A081 |
0.7 |
|
1989 |
Prorok M, Lawrence DS. Intrasubstrate steric interactions in the active site control the specificity of the cAMP-dependent protein kinase. Biochemical and Biophysical Research Communications. 158: 136-40. PMID 2912444 DOI: 10.1016/S0006-291X(89)80188-3 |
0.384 |
|
1989 |
Prorok M, Lawrence DS. Cryopreservation of the cyclic 3',5'-adenosine monophosphate-dependent protein kinase from bovine cardiac muscle. Journal of Biochemical and Biophysical Methods. 18: 167-75. PMID 2732419 DOI: 10.1016/0165-022X(89)90001-8 |
0.324 |
|
1985 |
Kaiser ET, Lawrence DS, Rokita SE. The chemical modification of enzymatic specificity. Annual Review of Biochemistry. 54: 565-95. PMID 2992359 DOI: 10.1146/Annurev.Bi.54.070185.003025 |
0.526 |
|
1985 |
Stevens RV, Lawrence DS. Camphorae: chiral intermediates fob the total synthesis of steroids. Part 2. An enantiospecific approach toward vitamin d metabolites Tetrahedron. 41: 93-100. DOI: 10.1016/S0040-4020(01)83472-4 |
0.424 |
|
1985 |
DOUGHTY MB, LAWRENCE DS. ChemInform Abstract: ON THE INTRAMOLECULAR CYCLIZATION OF A THIAZOLIUM SALT Chemischer Informationsdienst. 16. DOI: 10.1002/chin.198531213 |
0.422 |
|
1984 |
O'Brian CA, Lawrence DS, Kaiser ET, Weinstein IB. Protein kinase C phosphorylates the synthetic peptide Arg-Arg-Lys-Ala-Ser-Gly-Pro-Pro-Val in the presence of phospholipid plus either Ca2+ or a phorbol ester tumor promoter. Biochemical and Biophysical Research Communications. 124: 296-302. PMID 6238595 DOI: 10.1016/0006-291X(84)90951-3 |
0.532 |
|
1984 |
Kaiser ET, Lawrence DS. Chemical mutation of enzyme active sites. Science (New York, N.Y.). 226: 505-11. PMID 6238407 DOI: 10.1126/Science.6238407 |
0.516 |
|
1983 |
Stevens RV, Gaeta FCA, Lawrence DS. Camphorae: Chiral intermediates for the enantiospecific total synthesis of steroids. 1 Journal of the American Chemical Society. 105: 7713-7719. DOI: 10.1002/Chin.198414324 |
0.484 |
|
1982 |
Trueblood KN, Knobler CB, Lawrence DS, Stevens RV. Structures of the 1:1 complexes of 18-crown-6 with hydrazinium perchlorate, hydroxylammonium perchlorate, and methylammonium perchlorate Journal of the American Chemical Society. 104: 1355-1362. DOI: 10.1002/Chin.198226057 |
0.409 |
|
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