☰

Subra Kugathasan, M.D. - Publications

Affiliations: 
Pediatrics Emory University, Atlanta, GA 
Area:
Inflammatory Bowel Disease genetics
Tree Info Similar researchers PubMed Report error

351 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Zhao Q, Duck LW, Killian JT, Rosenberg AF, Mannon PJ, King RG, Denson LA, Kugathasan S, Janoff EN, Jenmalm MC, Elson CO. Crohn's patients and healthy infants share immunodominant B cell response to commensal flagellin peptide epitopes. Gastroenterology. PMID 39173722 DOI: 10.1053/j.gastro.2024.08.015  0.307
2024 Dennison TW, Edgar RD, Payne F, Nayak KM, Ross ADB, Cenier A, Glemas C, Giachero F, Foster AR, Harris R, Kraiczy J, Salvestrini C, Stavrou G, Torrente F, Brook K, ... ... Kugathasan S, et al. Patient-derived organoid biobank identifies epigenetic dysregulation of intestinal epithelial MHC-I as a novel mechanism in severe Crohn's Disease. Gut. PMID 38857990 DOI: 10.1136/gutjnl-2024-332043  0.334
2024 Aschenbrenner D, Nassiri I, Venkateswaran S, Pandey S, Page M, Drowley L, Armstrong M, Kugathasan S, Fairfax B, Uhlig HH. An isoform quantitative trait locus in SBNO2 links genetic susceptibility to Crohn's disease with defective antimicrobial activity. Nature Communications. 15: 4529. PMID 38806456 DOI: 10.1038/s41467-024-47218-3  0.34
2024 Brown M, Dodd A, Shi F, Greenwood E, Nagpal S, Kolachala VL, Kugathasan S, Gibson G. Concordant B and T Cell Heterogeneity Inferred from the Multiomic Landscape of Peripheral Blood Mononuclear Cells in a Crohn's Disease Cohort. Journal of Crohn's & Colitis. PMID 38613150 DOI: 10.1093/ecco-jcc/jjae055  0.343
2024 Khrom M, Long M, Dube S, Robbins L, Botwin GJ, Yang S, Mengesha E, Li D, Naito T, Bonthala NN, Ha C, Melmed G, Rabizadeh S, Syal G, Vasiliauskas E, ... ... Kugathasan S, et al. Comprehensive association analyses of extraintestinal manifestations in inflammatory bowel disease. Gastroenterology. PMID 38490347 DOI: 10.1053/j.gastro.2024.02.026  0.343
2023 Washburn S, Maddipatla SC, Murthy S, Dodd A, Pelia RS, Kolachala VL, Geem D, Matthews JD, Gibson G, Kugathasan S. Persistent Inflammation of the Rectum in Perianal Fistulizing Crohn's Disease Is Associated With Goblet Cell Function. Gastro Hep Advances. 3: 131-133. PMID 39132177 DOI: 10.1016/j.gastha.2023.09.002  0.33
2023 Astore C, Sharma S, Nagpal S, Cutler DJ, Rioux JD, Cho JH, McGovern DPB, Brant SR, Kugathasan S, Jordan IK, Gibson G. The role of admixture in the rare variant contribution to inflammatory bowel disease. Genome Medicine. 15: 97. PMID 37968638 DOI: 10.1186/s13073-023-01244-w  0.385
2023 Geem D, Hercules D, Pelia RS, Venkateswaran S, Griffiths A, Noe JD, Dotson JL, Snapper S, Rabizadeh S, Rosh JR, Baldassano RN, Markowitz JF, Walters TD, Ananthakrishnan A, Sharma G, ... ... Kugathasan S, et al. Progression of Pediatric Crohn's Disease Is Associated With Anti-Tumor Necrosis Factor Timing and Body Mass Index Z-Score Normalization. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. PMID 37802268 DOI: 10.1016/j.cgh.2023.08.042  0.33
2023 Harris RA, Bush AH, Eagar TN, Qian J, Greenwood MP, Opekun AR, Baldassano R, Guthery SL, Noe JD, Otley A, Rosh JR, Kugathasan S, Kellermayer R. Exome Sequencing Implicates DGKZ, ESRRA, and GXYLT1 for Modulating Granuloma Formation in Crohn's Disease. Journal of Pediatric Gastroenterology and Nutrition. PMID 37347142 DOI: 10.1097/MPG.0000000000003873  0.335
2023 Braun T, Sosnovski KE, Amir A, BenShoshan M, VanDussen KL, Karns R, Levhar N, Abbas-Egbariya H, Hadar R, Efroni G, Castel D, Avivi C, Rosen MJ, Grifiths AM, Walters TD, ... ... Kugathasan S, et al. Mucosal transcriptomics highlight lncRNAs implicated in ulcerative colitis, Crohn disease, and celiac disease. Jci Insight. PMID 37261910 DOI: 10.1172/jci.insight.170181  0.326
2023 Wu Y, Gettler K, Kars ME, Giri M, Li D, Bayrak CS, Zhang P, Jain A, Maffucci P, Sabic K, Van Vleck T, Nadkarni G, Denson LA, Ostrer H, Levine AP, ... ... Kugathasan S, et al. Identifying high-impact variants and genes in exomes of Ashkenazi Jewish inflammatory bowel disease patients. Nature Communications. 14: 2256. PMID 37080976 DOI: 10.1038/s41467-023-37849-3  0.334
2023 Venkateswaran S, Somineni HK, Matthews JD, Kilaru V, Hyams JS, Denson LA, Kellamayer R, Gibson G, Cutler DJ, Conneely KN, Smith AK, Kugathasan S. Longitudinal DNA methylation profiling of the rectal mucosa identifies cell-specific signatures of disease status, severity and clinical outcomes in ulcerative colitis cell-specific DNA methylation signatures of UC. Clinical Epigenetics. 15: 50. PMID 36964596 DOI: 10.1186/s13148-023-01462-4  0.308
2023 Howk AA, Smith SR, Polireddy K, Sauer CG, Kugathasan S, Glasson J, Chahine AA. The Use of the Perioperative Nutrition Score in Postoperative Pediatric Inflammatory Bowel Disease Patients. Journal of Pediatric Surgery. PMID 36914462 DOI: 10.1016/j.jpedsurg.2023.02.015  0.307
2022 Cordero RY, Cordero JB, Stiemke AB, Datta LW, Buyske S, Kugathasan S, McGovern DPB, Brant SR, Simpson CL. Trans-ancestry, Bayesian Meta-analysis Discovers 20 Novel Risk Loci for Inflammatory Bowel Disease in an African American, East Asian, and European Cohort. Human Molecular Genetics. PMID 36308435 DOI: 10.1093/hmg/ddac269  0.382
2022 Maddipatla SC, Kolachala VL, Venkateswaran S, Dodd AF, Pelia RS, Geem D, Yin H, Sun Y, Xu C, Mo A, Kosters A, Yang J, Matthews JD, Ghosn E, Kugathasan S, et al. Assessing Cellular and Transcriptional Diversity of Ileal Mucosa Among Treatment-Naïve and Treated Crohn's Disease. Inflammatory Bowel Diseases. PMID 36206201 DOI: 10.1093/ibd/izac201  0.348
2022 Sazonovs A, Stevens CR, Venkataraman GR, Yuan K, Avila B, Abreu MT, Ahmad T, Allez M, Ananthakrishnan AN, Atzmon G, Baras A, Barrett JC, Barzilai N, Beaugerie L, Beecham A, ... ... Kugathasan S, et al. Large-scale sequencing identifies multiple genes and rare variants associated with Crohn's disease susceptibility. Nature Genetics. PMID 36038634 DOI: 10.1038/s41588-022-01156-2  0.71
2022 Jurickova I, Bonkowski E, Angerman E, Novak E, Huron A, Akers G, Iwasawa K, Braun T, Hadar R, Hooker M, Han S, Cutler DJ, Okou DT, Kugathasan S, Jegga A, et al. Eicosatetraynoic Acid and Butyrate Regulate Human Intestinal Organoid Mitochondrial and Extracellular Matrix Pathways Implicated in Crohn's Disease Strictures. Inflammatory Bowel Diseases. PMID 35259271 DOI: 10.1093/ibd/izac037  0.681
2022 Venkateswaran S, Somineni HK, Kilaru V, Katrinli S, Prince J, Okou DT, Hyams JS, Denson LA, Kellermayer R, Gibson G, Cutler DJ, Smith AK, Kugathasan S, Conneely KN. Methylation Quantitative Trait Loci are Largely Consistent across Disease States in Crohn's disease. G3 (Bethesda, Md.). PMID 35172000 DOI: 10.1093/g3journal/jkac041  0.729
2021 Berger K, Somineni H, Prince J, Kugathasan S, Gibson G. Altered splicing associated with the pathology of inflammatory bowel disease. Human Genomics. 15: 47. PMID 34301333 DOI: 10.1186/s40246-021-00347-y  0.386
2021 Niklinska-Schirtz BJ, Venkateswaran S, Anbazhagan M, Kolachala VL, Prince J, Dodd A, Chinnadurai R, Gibson G, Denson LA, Cutler DJ, Jegga AG, Matthews JD, Kugathasan S. Ileal derived organoids from Crohn's disease patients show unique transcriptomic and secretomic signatures. Cellular and Molecular Gastroenterology and Hepatology. PMID 34271224 DOI: 10.1016/j.jcmgh.2021.06.018  0.329
2021 Somineni HK, Weitzner JH, Venkateswaran S, Dodd A, Prince J, Karikaran A, Sauer CG, Abramowicz S, Zwick ME, Cutler DJ, Okou DT, Chopra P, Kugathasan S. Site- and Taxa-Specific Disease-Associated Oral Microbial Structures Distinguish Inflammatory Bowel Diseases. Inflammatory Bowel Diseases. PMID 34002220 DOI: 10.1093/ibd/izab082  0.722
2021 Nayar S, Morrison JK, Giri M, Gettler K, Chuang LS, Walker LA, Ko HM, Kenigsberg E, Kugathasan S, Merad M, Chu J, Cho JH. A myeloid-stromal niche and gp130 rescue in NOD2-driven Crohn's disease. Nature. PMID 33789339 DOI: 10.1038/s41586-021-03484-5  0.318
2021 Somineni HK, Nagpal S, Venkateswaran S, Cutler DJ, Okou DT, Haritunians T, Simpson CL, Begum F, Datta LW, Quiros AJ, Seminerio J, Mengesha E, Alexander JS, Baldassano RN, Dudley-Brown S, ... ... Kugathasan S, et al. Whole-genome sequencing of African Americans implicates differential genetic architecture in inflammatory bowel disease. American Journal of Human Genetics. PMID 33600772 DOI: 10.1016/j.ajhg.2021.02.001  0.735
2021 Degenhardt F, Mayr G, Wendorff M, Boucher G, Ellinghaus E, Ellinghaus D, ElAbd H, Rosati E, Hübenthal M, Juzenas S, Abedian S, Vahedi H, Thelma BK, Yang SK, Ye BD, ... ... Kugathasan S, et al. Trans-ethnic analysis of the human leukocyte antigen region for ulcerative colitis reveals shared but also ethnicity-specific disease associations. Human Molecular Genetics. PMID 33555323 DOI: 10.1093/hmg/ddab017  0.676
2020 Potdar AA, Dube S, Naito T, Li K, Botwin G, Haritunians T, Li D, Casero D, Yang S, Bilsborough J, Perrigoue JG, Denson LA, Daly M, Targan SR, Fleshner P, ... ... Kugathasan S, et al. Altered intestinal ACE2 levels are associated with inflammation, severe disease and response to anti-cytokine therapy in IBD. Gastroenterology. PMID 33160965 DOI: 10.1053/j.gastro.2020.10.041  0.379
2020 Haberman Y, Minar P, Karns R, Dexheimer PJ, Ghandikota S, Tegge S, Shapiro D, Shuler B, Venkateswaran S, Braun T, Ta A, Walters TD, Baldassano RN, Noe JD, Rosh J, ... ... Kugathasan S, et al. Mucosal Inflammatory and Wound Healing Gene Programs Reveal Targets for Stricturing Behavior in Pediatric Crohn's Disease. Journal of Crohn's & Colitis. PMID 32770196 DOI: 10.1093/Ecco-Jcc/Jjaa166  0.396
2020 Mack DR, Saul B, Boyle B, Griffiths A, Sauer C, Markowitz J, LeLeiko N, Keljo D, Rosh JR, Baker SS, Steiner S, Heyman MB, Patel AS, Baldassano R, Noe J, ... ... Kugathasan S, et al. Analysis of Using the Total White Blood Cell Count to Define Severe New Onset Ulcerative Colitis in Children. Journal of Pediatric Gastroenterology and Nutrition. PMID 32520830 DOI: 10.1097/Mpg.0000000000002797  0.334
2020 Potdar AA, Dube S, Naito T, Botwin G, Haritunians T, Li D, Yang S, Bilsborough J, Denson LA, Daly M, Targan SR, Fleshner P, Braun J, Kugathasan S, Stappenbeck TS, et al. Reduced expression of COVID-19 host receptor, is associated with small bowel inflammation, more severe disease, and response to anti-TNF therapy in Crohn's disease. Medrxiv : the Preprint Server For Health Sciences. PMID 32511625 DOI: 10.1101/2020.04.19.20070995  0.348
2020 Mo A, Krishnakumar C, Arafat D, Dhere T, Iskandar H, Dodd A, Prince J, Kugathasan S, Gibson G. African Ancestry Proportion Influences Ileal Gene Expression in Inflammatory Bowel Disease. Cellular and Molecular Gastroenterology and Hepatology. PMID 32058087 DOI: 10.1016/J.Jcmgh.2020.02.001  0.427
2020 Haberman Ziv Y, Minar P, Karns R, Dexheimer P, Ghandikota S, Tegge S, Shapiro D, Shuler B, Venkateswaran S, Braun T, Aronow B, Gibson G, Hyams J, Kugathasan S, Jegga A, et al. DOP89 Pre-treatment mucosal inflammatory and wound healing gene programmes reveal mechanisms associated with future stricturing behaviour during 5-year follow-up in paediatric Crohn’s disease Journal of Crohn's and Colitis. 14: S127-S127. DOI: 10.1093/Ecco-Jcc/Jjz203.128  0.346
2020 Venkateswaran S, Kilaru V, Somineni H, Matthews J, Hyams J, Investigators P, Cutler D, Smith A, Conneely K, Kugathasan S. 15 LONGITUDINAL EVALUATION OF MUCOSAL DNA METHYLATION IN ULCERATIVE COLITIS SHOWS DISEASE-SPECIFIC CHANGES Gastroenterology. 158: S50-S51. DOI: 10.1053/J.Gastro.2019.11.143  0.345
2020 Niklinska-Schirtz B, Matthews J, Dodd A, Prince J, Biliya S, Venkateswaran S, Kugathasan S. P147 Patient Derived Intestinal Organoids Represent An Epithelial Model To Study Pediatric Crohns Disease Gastroenterology. 158. DOI: 10.1053/J.Gastro.2019.11.140  0.415
2020 Fondell AW, Mosha MH, Wright M, Maltz R, Boyle BM, Niklinska-Schirtz BJ, Kugathasan S, Gibson ME, Shapiro JM, Rosenheck S, Langseder A, Kennedy MC, Rosh JR, Hyams JS. Mo1903 HIGH RATES OF SURGERY PERSIST FOR CHILDREN PRESENTING WITH INTERNAL PENETRATING CROHN'S DISEASE: OBSERVATIONS FROM A MULTICENTER STUDY Gastroenterology. 158: S-971. DOI: 10.1016/S0016-5085(20)33100-0  0.381
2020 Shih T, Yusung S, Li D, Gonsky R, Botwin GJ, Casero D, Ziring D, Rabizadeh S, Denson LA, Kugathasan S, McGovern DP, Braun JG. Su1988 ENVIRONMENTAL EFFECT OF RESOLVED HUMAN CMV INFECTION AND NK RECEPTOR GENETICS IN PEDIATRIC CROHN'S DISEASE SUSCEPTIBILITY AND PHENOTYPE. Gastroenterology. 158: S-735. DOI: 10.1016/S0016-5085(20)32514-2  0.369
2020 Schirmer M, Denson LA, Walters TD, Griffiths AM, Mack DR, Leleiko NS, Markowitz J, Boyle BM, Shah S, Rosh JR, Kugathasan S, Vlamakis H, Hyams JS, Xavier R. Su1219 GUT MICROBIAL STRAINS AND METABOLITES IN DISEASE COURSE OF PEDIATRIC ULCERATIVE COLITIS Gastroenterology. 158: S-548. DOI: 10.1016/S0016-5085(20)32067-9  0.382
2020 TA A, Ollberding N, Karns R, Haberman Y, Baldassano RN, Markowitz J, Heyman M, Kirschner BS, Oliva-Hemker M, Pfefferkorn MD, Kellermayer R, Snapper SB, Rabizadeh S, Hyams JS, Kugathasan S, et al. 1162 BASELINE ILEAL LUMINAL NARROWING IS ASSOCIATED WITH SPECIFIC PRE-TREATMENT MUCOSAL GENE PROGRAMS AND MICROBIAL SHIFTS AND SUBSEQUENT LIKELIHOOD OF TRANSMURAL HEALING IN PEDIATRIC CROHN'S DISEASE Gastroenterology. 158: S-234-S-235. DOI: 10.1016/S0016-5085(20)31272-5  0.396
2020 Hyams JS, Walters TD, Brimacombe M, Mack DR, Griffiths AM, Boyle BM, Leleiko NS, Markowitz J, Sauer CG, Keljo DJ, Kugathasan S, Haberman Y, Denson LA. 1161 CLINICAL AND HOST BIOLOGICAL FACTORS CAN PREDICT COLECTOMY RISK IN CHILDREN NEWLY DIAGNOSED WITH ULCERATIVE COLITIS Gastroenterology. 158: S-234. DOI: 10.1016/S0016-5085(20)31271-3  0.31
2020 Haberman Y, Minar PP, Karns R, Dexheimer PJ, Ghandikota S, Tegge S, Shapiro D, Shuler B, Venkateswaran S, Braun T, Walters TD, Baldassano RN, Noe JD, Kellermayer R, Markowitz J, ... ... Kugathasan S, et al. 935 PRE-TREATMENT MUCOSAL INFLAMMATORY AND WOUND HEALING GENE PROGRAMS REVEAL MECHANISMS ASSOCIATED WITH FUTURE STRICTURING BEHAVIOR DURING FIVE YEAR FOLLOW-UP IN PEDIATRIC CROHN'S DISEASE Gastroenterology. 158: S-187-S-188. DOI: 10.1016/S0016-5085(20)31152-5  0.395
2020 Ungaro RC, Hu L, Ji J, Kugathasan S, Dubinsky M, Sands BE, Cho JH. 764 MACHINE LEARNING IDENTIFIES NOVEL BLOOD PROTEOMIC PREDICTORS OF PENETRATING AND STRICTURING COMPLICATIONS IN NEWLY DIAGNOSED PEDIATRIC CROHN'S DISEASE Gastroenterology. 158: S-158-S-159. DOI: 10.1016/S0016-5085(20)31082-9  0.347
2020 Venkateswaran S, Somineni HK, Matthews J, Kilaru V, Denson LA, Hyams JS, Investigators P, Cutler DJ, Smith AK, Conneely KN, Kugathasan S. 614 RECTAL TISSUE DNA METHYLATION IN ULCERATIVE COLITIS SHOWS DISEASE-SPECIFIC ASSOCIATIONS: INSIGHTS FROM LONGITUDINAL ANALYSIS OF PROTECT STUDY PARTICIPANTS Gastroenterology. 158: S-131. DOI: 10.1016/S0016-5085(20)31007-6  0.338
2020 Niklinska-Schirtz BJ, Matthews J, Venkateswaran S, Prince J, Dodd A, Cutler DJ, Kugathasan S. 589 Pediatric Crohn'S Disease Patient Derived Organoids Show Persistent Transcriptomic Epithelial Cell Defects Gastroenterology. 158. DOI: 10.1016/S0016-5085(20)30995-1  0.414
2020 Dubinsky MC, Sockolow R, Kugathasan S, Hemperly A, Rabizadeh S, Casteele NV. Sa1869 COMBINATION OF SERUM ENDOSCOPIC HEALING INDEX AND THERAPEUTIC DRUG MONITORING ALLOWS FOR NON-INVASIVE TIGHT DISEASE MANAGEMENT IN PEDIATRIC PATIENTS WITH CROHN'S DISEASE TREATED WITH ANTI-TUMOR NECROSIS FACTOR THERAPY Gastroenterology. 158. DOI: 10.1016/S0016-5085(20)30802-7  0.395
2019 Martin JC, Chang C, Boschetti G, Ungaro R, Giri M, Grout JA, Gettler K, Chuang LS, Nayar S, Greenstein AJ, Dubinsky M, Walker L, Leader A, Fine JS, Whitehurst CE, ... ... Kugathasan S, et al. Single-Cell Analysis of Crohn's Disease Lesions Identifies a Pathogenic Cellular Module Associated with Resistance to Anti-TNF Therapy. Cell. PMID 31474370 DOI: 10.1016/J.Cell.2019.08.008  0.355
2019 Naramore SK, Bennett WE, Jiang G, Kugathasan S, Denson LA, Hyams JS, Steiner SJ. Serologic, but not Genetic, Markers are Associated with Impaired Anthropometrics at Diagnosis of Pediatric Crohn's Disease. Journal of Pediatric Gastroenterology and Nutrition. PMID 31393333 DOI: 10.1097/Mpg.0000000000002462  0.454
2019 Cohen RZ, Schoen BT, Kugathasan S, Sauer CG. Management of Anti-drug Antibodies (ADA) to Biologic Medications in Children with Inflammatory Bowel Disease. Journal of Pediatric Gastroenterology and Nutrition. PMID 31335833 DOI: 10.1097/Mpg.0000000000002440  0.416
2019 Niklinska-Schirtz BJ, Kugathasan S. Anti-TNF Therapy Is Emerging as the Primary Treatment Modality in Pediatric Inflammatory Bowel Disease. Inflammatory Bowel Diseases. PMID 31323085 DOI: 10.1093/Ibd/Izz158  0.401
2019 Stevens JP, Ballengee CR, Chandradevan R, Thompson AB, Schoen BT, Kugathasan S, Sauer CG. Performance of Interferon-Gamma Release Assays for Tuberculosis Screening in Pediatric Inflammatory Bowel Disease. Journal of Pediatric Gastroenterology and Nutrition. PMID 31261245 DOI: 10.1097/Mpg.0000000000002428  0.347
2019 Venkateswaran S, Denson LA, Jurickova I, Dodd A, Zwick ME, Cutler DJ, Kugathasan S, Okou DT. Neutrophil GM-CSF signaling in inflammatory bowel disease patients is influenced by non-coding genetic variants. Scientific Reports. 9: 9168. PMID 31235766 DOI: 10.1038/S41598-019-45701-2  0.705
2019 Lloyd-Price J, Arze C, Ananthakrishnan AN, Schirmer M, Avila-Pacheco J, Poon TW, Andrews E, Ajami NJ, Bonham KS, Brislawn CJ, Casero D, Courtney H, Gonzalez A, Graeber TG, Hall AB, ... ... Kugathasan S, et al. Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases. Nature. 569: 655-662. PMID 31142855 DOI: 10.1038/S41586-019-1237-9  0.476
2019 Tokarz R, Hyams JS, Mack DR, Boyle B, Griffiths AM, LeLeiko NS, Sauer CG, Shah S, Markowitz J, Baker SS, Rosh J, Baldassano RN, Kugathasan S, Walters T, Tagliafierro T, et al. Characterization of Stool Virome in Children Newly Diagnosed With Moderate to Severe Ulcerative Colitis. Inflammatory Bowel Diseases. PMID 31112614 DOI: 10.1093/Ibd/Izz099  0.337
2019 Scott FI, Rubin DT, Kugathasan S, Bousvaros A, Elson CO, Newberry RD, Melmed GY, Pekow J, Fleshman JW, Boyle BM, Mahadevan U, Cannon LM, Long MD, Cross RK, Ha CY, et al. Challenges in IBD Research: Pragmatic Clinical Research. Inflammatory Bowel Diseases. 25: S40-S47. PMID 31095704 DOI: 10.1093/Ibd/Izz085  0.321
2019 Wu J, Lubman DM, Kugathasan S, Denson LA, Hyams JS, Dubinsky MC, Griffiths AM, Baldassano RN, Noe JD, Rabizadeh S, Gulati AS, Rosh JR, Crandall WV, Higgins PDR, Stidham RW. Serum Protein Biomarkers of Fibrosis Aid in Risk Stratification of Future Stricturing Complications in Pediatric Crohn's Disease. The American Journal of Gastroenterology. 114: 777-785. PMID 31058681 DOI: 10.14309/Ajg.0000000000000237  0.429
2019 Wright M, Chandrakasan S, Okou DT, Yin H, Jurickova I, Denson LA, Kugathasan S. Early Onset Granulomatous Colitis Associated with a Mutation in NCF4 Resolved with Hematopoietic Stem Cell Transplantation. The Journal of Pediatrics. PMID 31027832 DOI: 10.1016/J.Jpeds.2019.03.042  0.683
2019 Ahmed S, Vachaparambil C, Kugathasan S. Pediatric inflammatory bowel disease: continuous lessons for adult inflammatory bowel disease. Current Opinion in Gastroenterology. PMID 31021923 DOI: 10.1097/MOG.0000000000000548  0.354
2019 Hyams JS, Davis Thomas S, Gotman N, Haberman Y, Karns R, Schirmer M, Mo A, Mack DR, Boyle B, Griffiths AM, LeLeiko NS, Sauer CG, Keljo DJ, Markowitz J, Baker SS, ... ... Kugathasan S, et al. Clinical and biological predictors of response to standardised paediatric colitis therapy (PROTECT): a multicentre inception cohort study. Lancet (London, England). PMID 30935734 DOI: 10.1016/S0140-6736(18)32592-3  0.387
2019 Lindoso L, Ballengee CR, Patel KP, Romero R, Caltharp S, Alazraki AL, Kugathasan S. Multilocus Heterotopic Gastric Mucosa of Ileum Masquerading as VEOIBD in a Newborn. Pediatrics. PMID 30898843 DOI: 10.1542/Peds.2018-2398  0.364
2019 Somineni HK, Venkateswaran S, Kilaru V, Marigorta UM, Mo A, Okou DT, Kellermayer R, Mondal K, Cobb D, Walters TD, Griffiths A, Noe JD, Crandall WV, Rosh JR, Mack DR, ... ... Kugathasan S, et al. Blood-derived DNA Methylation Signatures of Crohn's Disease and Severity of Intestinal Inflammation. Gastroenterology. PMID 30779925 DOI: 10.1053/J.Gastro.2019.01.270  0.744
2019 Gettler K, Giri M, Kenigsberg E, Martin J, Chuang LS, Hsu NY, Denson LA, Hyams JS, Griffiths A, Noe JD, Crandall WV, Mack DR, Kellermayer R, Abraham C, Hoffman G, ... Kugathasan S, et al. Prioritizing Crohn's disease genes by integrating association signals with gene expression implicates monocyte subsets. Genes and Immunity. PMID 30692607 DOI: 10.1038/S41435-019-0059-Y  0.384
2019 Krishnakumar C, Ballengee CR, Liu C, Kim MO, Baker SS, Baldassano RN, Cohen SA, Crandall WV, Denson LA, Dubinsky MC, Evans J, Gokhale R, Griffiths A, Guthery SL, Oliva-Hemker M, ... ... Kugathasan S, et al. Variation in Care in the Management of Children With Crohn's Disease: Data From a Multicenter Inception Cohort Study. Inflammatory Bowel Diseases. PMID 30601983 DOI: 10.1093/Ibd/Izy363  0.391
2019 Ahmed S, Iskandar H, Liu Z, Mondal K, Markowitz J, Hyams J, Denson L, Walters T, Dubinsky MC, Kugathasan S. Persisting Malnutrition After Medical Therapy in Children With Crohnʼs Disease Is Associated With Increased Rates of Surgery and Complicated Disease Behavior American Journal of Gastroenterology. 114: S459-S460. DOI: 10.14309/01.Ajg.0000592708.51441.3A  0.378
2019 Haberman Y, Karns R, Dexheimer P, Schirmer M, Braun T, Collins M, Mo A, Rosen M, Gotman N, Kugathasan S, Walters TD, Gibson G, Thomas SD, Huttenhower C, Xavier RJ, et al. OP19 Corticosteroid response rectal gene signature and associated microbial variation in treatment naïve ulcerative colitis Journal of Crohns & Colitis. 13. DOI: 10.1093/Ecco-Jcc/Jjy222.018  0.314
2019 Venkateswaran S, Somineni H, Kilaru V, Cutler D, Smith A, Investigators R, Conneely K, Kugathasan S. P108 Longitudinal Mqtl Study In Blood From Pediatric Crohn’S Disease Patients Gastroenterology. 156. DOI: 10.1053/J.Gastro.2019.01.173  0.373
2019 Nagpal S, Mo A, Hyams JS, Marigorta U, Mack DR, Boyle BM, Griffiths AM, Leleiko NS, Baldassano RN, Rosh JR, Keljo DJ, Markowitz J, Walters TD, Kugathasan S, Denson LA, et al. Tu1760 – Alterations in Expression Quantitative Trait Loci from Diagnosis to Recovery in Pediatric Ulcerative Colitis Gastroenterology. 156: S-1113-S-1114. DOI: 10.1016/S0016-5085(19)39746-X  0.317
2019 Venkateswaran S, Somineni HK, Kilaru V, Hyams JS, Denson LA, Cutler DJ, Smith AK, Conneely KN, Kugathasan S. Tu1159 – Blood Mqtl Effects are Consistent During the Course of the Disease Regardless of Remission Or Relapse Status in Pediatric Crohn’s Disease Patients Gastroenterology. 156: S-967. DOI: 10.1016/S0016-5085(19)39373-4  0.433
2019 Fondell AW, Wang Z, Mack DR, Griffiths AM, Boyle BM, Patel AS, Sauer CG, Markowitz J, Rosh JR, Leleiko NS, Keljo DJ, Walters TD, Kugathasan S, Denson LA, Hyams JS. Su1790 – Infliximab Rescue Less Effective in Preventing Colectomy Early in the Course of Newly Diagnosed Ulcerative Colitis Gastroenterology. 156: S-612. DOI: 10.1016/S0016-5085(19)38427-6  0.318
2019 Somineni HK, Haritunians T, Simpson CL, Cutler DJ, Okou D, Itan Y, Venkateswaran S, Stevens C, Datta LW, Dhere TA, Lazarev M, Consortium EAAI, Zwick ME, Cho JH, Daly MJ, ... ... Kugathasan S, et al. Su1028 – Whole-Genome Sequencing of African Americans Identifies Novel Rare Variants Associated with Inflammatory Bowel Disease Gastroenterology. 156: S-488-S-489. DOI: 10.1016/S0016-5085(19)38082-5  0.725
2019 Krishnakumar C, Ananthakrishnan A, Boyle BM, Griffiths AM, Leleiko NS, Mack DR, Markowitz J, Rosh JR, Sauer CG, Walters TD, Denson LA, Hyams JS, Kugathasan S. 302 – Early Change in Fecal Calprotectin Predicts One Year Clinical Outcome in Children Newly Diagnosed with Ulcerative Colitis Gastroenterology. 156: S-60. DOI: 10.1016/S0016-5085(19)36934-3  0.3
2019 Whaley KG, Xiong Y, Karns R, Hyams JS, Kugathasan S, Boyle BM, Walters TD, Kelsen JR, Leleiko NS, Waddell A, Fox S, Haberman Y, Minar PP, Denson LA, Thomas S, et al. 235 – Early Infliximab Pharmacokinetics and Week One Clinical Response in Pediatric Acute Severe Ulcerative Colitis: the Arch Study Gastroenterology. 156: S-44. DOI: 10.1016/S0016-5085(19)36891-X  0.313
2018 Venkateswaran S, Marigorta UM, Denson LA, Hyams JS, Gibson G, Kugathasan S. Bowel Location Rather Than Disease Subtype Dominates Transcriptomic Heterogeneity in Pediatric IBD. Cellular and Molecular Gastroenterology and Hepatology. 6: 474-476.e3. PMID 30364773 DOI: 10.1016/J.Jcmgh.2018.07.001  0.383
2018 Schirmer M, Denson L, Vlamakis H, Franzosa EA, Thomas S, Gotman NM, Rufo P, Baker SS, Sauer C, Markowitz J, Pfefferkorn M, Oliva-Hemker M, Rosh J, Otley A, Boyle B, ... ... Kugathasan S, et al. Compositional and Temporal Changes in the Gut Microbiome of Pediatric Ulcerative Colitis Patients Are Linked to Disease Course. Cell Host & Microbe. 24: 600-610.e4. PMID 30308161 DOI: 10.1016/J.Chom.2018.09.009  0.319
2018 Lindoso L, Mondal K, Venkateswaran S, Somineni HK, Ballengee C, Walters TD, Griffiths A, Noe JD, Crandall W, Snapper S, Rabizadeh S, Rosh JR, LeLeiko N, Guthery S, Mack D, ... ... Kugathasan S, et al. The Effect of Early-Life Environmental Exposures on Disease Phenotype and Clinical Course of Crohn's Disease in Children. The American Journal of Gastroenterology. PMID 30267029 DOI: 10.1038/S41395-018-0239-9  0.464
2018 Kelly D, Kotliar M, Woo V, Jagannathan S, Whitt J, Moncivaiz J, Aronow BJ, Dubinsky MC, Hyams JS, Markowitz JF, Baldassano RN, Stephens MC, Walters TD, Kugathasan S, Haberman Y, et al. Microbiota-sensitive epigenetic signature predicts inflammation in Crohn's disease. Jci Insight. 3. PMID 30232290 DOI: 10.1172/Jci.Insight.122104  0.398
2018 Ballengee CR, Stidham RW, Liu C, Kim MO, Prince J, Mondal K, Baldassano R, Dubinsky M, Markowitz J, Leleiko N, Hyams J, Denson L, Kugathasan S. Association Between Plasma Level of Collagen Type III alpha 1 Chain and Development of Strictures in Pediatric Patients With Crohn's Disease. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. PMID 30213581 DOI: 10.1016/J.Cgh.2018.09.008  0.39
2018 Somineni HK, Kugathasan S. The microbiome in inflammatory bowel disease: from prevailing clinical evidence to future possibilities. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. PMID 30196163 DOI: 10.1016/J.Cgh.2018.08.078  0.402
2018 Chen JS, Hu F, Kugathasan S, Jorde LB, Nix D, Rutherford A, Denson L, Watkins WS, Prahalad S, Huff C, Guthery SL. Targeted Gene Sequencing in Children with Crohn's Disease and Their Parents: Implications for Missing Heritability. G3 (Bethesda, Md.). 8: 2881-2888. PMID 30166421 DOI: 10.1534/G3.118.200404  0.358
2018 Denson LA, Jurickova I, Karns R, Shaw KA, Cutler DJ, Okou D, Alexander Valencia C, Dodd A, Mondal K, Aronow BJ, Haberman Y, Linn A, Price A, Bezold R, Lake K, ... ... Kugathasan S, et al. Genetic and Transcriptomic Variation Linked to Neutrophil Granulocyte-Macrophage Colony-Stimulating Factor Signaling in Pediatric Crohn's Disease. Inflammatory Bowel Diseases. PMID 30124884 DOI: 10.1093/Ibd/Izy265  0.726
2018 Mo A, Marigorta UM, Arafat D, Chan LHK, Ponder L, Jang SR, Prince J, Kugathasan S, Prahalad S, Gibson G. Disease-specific regulation of gene expression in a comparative analysis of juvenile idiopathic arthritis and inflammatory bowel disease. Genome Medicine. 10: 48. PMID 29950172 DOI: 10.1186/s13073-018-0558-x  0.379
2018 Picoraro JA, Lee D, Heller CA, Weaver A, Hyams JS, Conklin LS, Otley A, Ziring D, Kugathasan S, Rosh JR, Mulberg A, Denson LA, Kappelman MD, Grossman AB, Bousvaros A, et al. Pediatric Inflammatory Bowel Disease Clinical Innovations Meeting of the Crohn's & Colitis Foundation: Charting the Future of Pediatric IBD. Inflammatory Bowel Diseases. PMID 29931102 DOI: 10.1093/Ibd/Izy205  0.474
2018 Chandradevan R, Hofmekler T, Mondal K, Harun N, Venkateswaran S, Somineni HK, Ballengee CR, Kim MO, Griffiths A, Noe JD, Crandall WV, Snapper S, Rabizadeh S, Rosh JR, Walters TD, ... ... Kugathasan S, et al. Evolution of Pediatric Inflammatory Bowel Disease Unclassified (IBD-U): Incorporated With Serological and Gene Expression Profiles. Inflammatory Bowel Diseases. PMID 29860529 DOI: 10.1093/Ibd/Izy136  0.506
2018 Steenland K, Kugathasan S, Barr DB. PFOA and ulcerative colitis. Environmental Research. 165: 317-321. PMID 29777922 DOI: 10.1016/J.Envres.2018.05.007  0.385
2018 Ballengee CR, Kugathasan S. Response to Biologics Delay Progression of Crohn's Disease in Children but Not Early Surgery. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. PMID 29775795 DOI: 10.1016/J.Cgh.2018.05.010  0.384
2018 Spencer EA, Davis SM, Mack DR, Boyle BM, Griffiths AM, LeLeiko NS, Sauer CG, Keljo DJ, Markowitz JF, Baker SS, Rosh JR, Baldassano RN, Oliva-Hemker M, Pfefferkorn MD, Otley AR, ... ... Kugathasan S, et al. Serologic Reactivity Reflects Clinical Expression of Ulcerative Colitis in Children. Inflammatory Bowel Diseases. PMID 29718391 DOI: 10.1093/Ibd/Izy009  0.501
2018 Shaw KA, Cutler DJ, Okou D, Dodd A, Aronow BJ, Haberman Y, Stevens C, Walters TD, Griffiths A, Baldassano RN, Noe JD, Hyams JS, Crandall WV, Kirschner BS, Heyman MB, ... ... Kugathasan S, et al. Genetic variants and pathways implicated in a pediatric inflammatory bowel disease cohort. Genes and Immunity. PMID 29593342 DOI: 10.1038/S41435-018-0015-2  0.744
2018 Venkateswaran S, Prince J, Cutler DJ, Marigorta UM, Okou DT, Prahalad S, Mack D, Boyle B, Walters T, Griffiths A, Sauer CG, LeLeiko N, Keljo D, Markowitz J, Baker SS, ... ... Kugathasan S, et al. Enhanced Contribution of HLA in Pediatric Onset Ulcerative Colitis. Inflammatory Bowel Diseases. 24: 829-838. PMID 29562276 DOI: 10.1093/Ibd/Izx084  0.729
2018 Denson LA, Jurickova I, Karns R, Shaw KA, Cutler DJ, Okou D, Dodd A, Quinn K, Mondal K, Aronow BJ, Haberman Y, Linn A, Price A, Bezold R, Lake K, ... ... Kugathasan S, et al. Clinical and Genomic Correlates of Neutrophil Reactive Oxygen Species Production in Pediatric Patients with Crohn's Disease. Gastroenterology. PMID 29454792 DOI: 10.1053/J.Gastro.2018.02.016  0.74
2018 Haberman Y, BenShoshan M, Di Segni A, Dexheimer PJ, Braun T, Weiss B, Walters TD, Baldassano RN, Noe JD, Markowitz J, Rosh J, Heyman MB, Griffiths AM, Crandall WV, Mack DR, ... ... Kugathasan S, et al. Long ncRNA Landscape in the Ileum of Treatment-Naive Early-Onset Crohn Disease. Inflammatory Bowel Diseases. 24: 346-360. PMID 29361088 DOI: 10.1093/Ibd/Izx013  0.393
2018 Schirmer M, Franzosa EA, Lloyd-Price J, McIver LJ, Schwager R, Poon TW, Ananthakrishnan AN, Andrews E, Barron G, Lake K, Prasad M, Sauk J, Stevens B, Wilson RG, Braun J, ... ... Kugathasan S, et al. Dynamics of metatranscription in the inflammatory bowel disease gut microbiome. Nature Microbiology. PMID 29311644 DOI: 10.1038/S41564-017-0089-Z  0.338
2018 Somineni HK, Venkateswaran S, Kilaru V, Chopra P, Okou DT, Hyams JS, Denson LA, Cutler DJ, Gibson G, Conneely KN, Smith AK, Kugathasan S. 10 EPIGENOME-WIDE ASSOCIATION STUDY IDENTIFIED SHARED METHYLOMIC CONTRIBUTIONS TO SUSCEPTIBILITY AND PROGRESSION IN PEDIATRIC CROHN’S DISEASE Inflammatory Bowel Diseases. 24: S71-S71. DOI: 10.1093/ibd/izy038.017  0.725
2018 Haberman Y, BenShoshan M, Segni AD, Dexheimer PJ, Braun T, Weiss B, Avivi C, Barshack I, Anikster Y, Aronow B, Hyams JS, Kugathasan S, Denson LA. DOP015 Dysregulation of cell-type-specific long ncRNA in the ileum of treatment naïve early onset Crohn disease Journal of Crohns & Colitis. 12. DOI: 10.1093/Ecco-Jcc/Jjx180.052  0.368
2018 Turner D, Koletzko S, Winter H, Baldassano R, Dubinsky M, Faubion W, Hyams J, Kugathasan S, Rosh J, Escher J, Griffiths A, Kierkus J, Russell R, Heap G, Arikan D, et al. DOP008 Safety of adalimumab in children and adolescents with moderate-to-severe Crohn’s disease: interim results of the CAPE registry Journal of Crohn's and Colitis. 12: S035-S035. DOI: 10.1093/Ecco-Jcc/Jjx180.045  0.338
2018 Somineni HK, Venkateswaran S, Kilaru V, Chopra P, Okou DT, Hyams JS, Denson LA, Cutler DJ, Gibson G, Conneely KN, Smith AK, Kugathasan S. 10 EPIGENOME-WIDE ASSOCIATION STUDY IDENTIFIED SHARED METHYLOMIC CONTRIBUTIONS TO SUSCEPTIBILITY AND PROGRESSION IN PEDIATRIC CROHN'S DISEASE Gastroenterology. 154: S101. DOI: 10.1053/J.Gastro.2017.11.238  0.753
2018 Le K, Somineni H, Venkateswaran S, Chopra P, Karikaran A, Dodd A, Prince J, Weitzner J, Kugathasan S. P150 MICROBIOME RISK SCORE (MRS) IN THE DIAGNOSIS AND CLASSIFICATION OF INFLAMMATORY BOWEL DISEASE Gastroenterology. 154: S79. DOI: 10.1053/J.Gastro.2017.11.199  0.396
2018 Bamidele AO, Svingen PA, Sagstetter MR, Gonzalez M, Sarmento OF, Braga Neto MB, Friton JJ, Kugathasan S, Lomberk G, Urrutia RA, Faubion WA. 15 DISRUPTION OF FOXP3-EZH2 INTERACTION BY GENETIC MUTATION OR SIGNALING-INDUCED INACTIVATION REPRESENTS A NOVEL PATHOBIOLOGICAL MECHANISM IN INFLAMMATORY BOWEL DISEASE Inflammatory Bowel Diseases. 24: S10-S11. DOI: 10.1053/J.Gastro.2017.11.063  0.393
2018 Denson LA, Jurickova I, Karns R, Shaw KA, Cutler DJ, Okou D, Dodd A, Mondal K, Aronow BJ, Haberman Y, Linn A, Price A, Bezold R, Lake K, Jackson K, ... ... Kugathasan S, et al. 27 CLINICAL AND GENOMIC CORRELATES OF NEUTROPHIL GRANULOCYTE-MACROPHAGE COLONY STIMULATING FACTOR SIGNALING IN PEDIATRIC CROHN DISEASE Inflammatory Bowel Diseases. 24: S7-S8. DOI: 10.1053/J.Gastro.2017.11.051  0.711
2018 Denson LA, Jurickova I, Karns R, Shaw KA, Cutler DJ, Okou D, Dodd A, Mondal K, Aronow BJ, Haberman Y, Linn A, Price A, Bezold R, Lake K, Jackson K, ... ... Kugathasan S, et al. 27 CLINICAL AND GENOMIC CORRELATES OF NEUTROPHIL GRANULOCYTE-MACROPHAGE COLONY STIMULATING FACTOR SIGNALING IN PEDIATRIC CROHN DISEASE Gastroenterology. 154: S10-S11. DOI: 10.1053/j.gastro.2017.11.051  0.69
2018 Marigorta U, Venkateswaran S, Denson LA, Hyams JS, Gibson G, Kugathasan S. Tu1798 - Transcriptome Variation in Ileal and Rectal Biopsies of Pediatric IBD Patients Gastroenterology. 154: S-1022. DOI: 10.1016/S0016-5085(18)33424-3  0.337
2018 Wu J, Lubman DM, Kugathasan S, Denson LA, Hyams JS, Dubinsky M, Griffiths AM, Baldassano RN, Noe JD, Crandall WV, Higgins PD, Stidham RW. Su1878 - Serum Markers can Predict Future Fibrostenotic Complications at the Time of Diagnosis in Pediatric Crohn's Disease Gastroenterology. 154: S-616-S-617. DOI: 10.1016/S0016-5085(18)32224-8  0.386
2018 Bauman LE, Haberman Y, Hao L, Patel S, Tangpricha V, Karns R, Dexheimer PJ, Collins MH, Rosen MJ, Bonkowski E, Marquis A, Gotman N, Rufo PA, Baker SS, Sauer CG, ... ... Kugathasan S, et al. Sa2009 - Bioavailable Serum Vitamin D and Rectal Vitamin D Receptor Expression at Diagnosis in Pediatric Ulcerative Colitis: Associations with Disease Severity, Clinical Outcomes, and Rectal Patterns of Gene Expression Gastroenterology. 154: S-446. DOI: 10.1016/S0016-5085(18)31745-1  0.304
2018 Haberman Y, Schirmer M, Dexheimer PJ, Karns R, Braun T, Kim M, Walters TD, Baldassano RN, Noe JD, Rosh JR, Markowitz J, Crandall WV, Mack DR, Griffiths AM, Heyman MB, ... ... Kugathasan S, et al. 740 - Age-of-Onset Dependent Ileal Immune Maturation and Reduced Alpha-Defensin in Pediatric Crohn Disease with Already Established Dysbiosis Gastroenterology. 154: S-154. DOI: 10.1016/S0016-5085(18)30930-2  0.342
2018 Schirmer M, Vlamakis H, Denson LA, Franzosa EA, Davis S, Rufo PA, Baker SS, Sauer CG, Markowitz J, Pfefferkorn MD, Oliva-Hemker M, Rosh JR, Otley A, Boyle BM, Mack DR, ... ... Kugathasan S, et al. 634 - Gut Microbial Factors Implicated in Disease Progression and Treatment Response in Pediatric Ulcerative Colitis Gastroenterology. 154: S-133. DOI: 10.1016/S0016-5085(18)30871-0  0.43
2018 Haberman Y, Karns R, Dexheimer PJ, Bauman LE, Collins MH, Rosen MJ, Bonkowski E, Marquis A, Gotman N, Rufo PA, Baker SS, Sauer CG, Markowitz J, Pfefferkorn MD, Rosh JR, ... ... Kugathasan S, et al. 589 - The Treatment Naive Rectal Transcriptome Identifies Pathways Mediating Clinical and Endoscopic Severity and Response to Initial Therapy in Pediatric Ulcerative Colitis Gastroenterology. 154: S-124. DOI: 10.1016/S0016-5085(18)30842-4  0.327
2018 Hyams JS, Wang Z, Davis S, Mack DR, Boyle BM, Griffiths AM, Leleiko NS, Baldassano RN, Marquis A, Gotman N, Keljo DJ, Rosh JR, Serrano J, Kugathasan S, Markowitz J, et al. 498 - Defining Remission in Pediatric Ulcerative Colitis: Evidence from the Protect Study Gastroenterology. 154: S-113-S-114. DOI: 10.1016/S0016-5085(18)30815-1  0.366
2018 Jurickova I, Karns R, Cutler DJ, Okou D, Dodd A, Mondal K, Aronow BJ, Haberman Y, Linn A, Price A, Bezold R, Lake K, Jackson K, Walters TD, Griffiths AM, ... ... Kugathasan S, et al. 378 - Genomic Correlates of Reduced Neutrophil Granulocytemacrophage Colony Stimulating Factor Signaling in Stricturing Pediatric Crohn Disease Gastroenterology. 154: S-89-S-90. DOI: 10.1016/S0016-5085(18)30746-7  0.715
2017 Bertha M, Vasantharoopan A, Kumar A, Bruce BB, Prince J, Hofmekler T, Okou D, Chopra P, Wang G, Sauer C, Landers CJ, Hussain SZ, Cross RK, Baldassano RN, Kappelman MD, ... ... Kugathasan S, et al. IBD Serology and Disease Outcomes in African Americans With Crohn's Disease. Inflammatory Bowel Diseases. 24: 209-216. PMID 29272484 DOI: 10.1093/Ibd/Izx021  0.739
2017 Hall AB, Yassour M, Sauk J, Garner A, Jiang X, Arthur T, Lagoudas GK, Vatanen T, Fornelos N, Wilson R, Bertha M, Cohen M, Garber J, Khalili H, Gevers D, ... ... Kugathasan S, et al. A novel Ruminococcus gnavus clade enriched in inflammatory bowel disease patients. Genome Medicine. 9: 103. PMID 29183332 DOI: 10.1186/S13073-017-0490-5  0.336
2017 Schwerd T, Bryant RV, Pandey S, Capitani M, Meran L, Cazier JB, Jung J, Mondal K, Parkes M, Mathew CG, Fiedler K, McCarthy DJ, ... ... Kugathasan S, et al. NOX1 loss-of-function genetic variants in patients with inflammatory bowel disease. Mucosal Immunology. PMID 29091079 DOI: 10.1038/Mi.2017.74  0.385
2017 Kugathasan S, Denson LA, Hyams JS. Exclusive and partial enteral nutrition for Crohn's disease - Authors' reply. Lancet (London, England). 390: 1486-1487. PMID 28952446 DOI: 10.1016/S0140-6736(17)32157-8  0.437
2017 Hyams JS, Davis S, Mack DR, Boyle B, Griffiths AM, LeLeiko NS, Sauer CG, Keljo DJ, Markowitz J, Baker SS, Rosh J, Baldassano RN, Patel A, Pfefferkorn M, Otley A, ... ... Kugathasan S, et al. Factors associated with early outcomes following standardised therapy in children with ulcerative colitis (PROTECT): a multicentre inception cohort study. The Lancet. Gastroenterology & Hepatology. PMID 28939374 DOI: 10.1016/S2468-1253(17)30252-2  0.382
2017 Boyle B, Collins MH, Wang Z, Mack D, Griffiths A, Sauer C, Markowitz J, LeLeiko N, Keljo D, Rosh J, Baker SS, Pfefferkorn M, Heyman M, Patel A, Baldassano R, ... ... Kugathasan S, et al. Histologic Correlates of Clinical and Endoscopic Severity in Children Newly Diagnosed With Ulcerative Colitis. The American Journal of Surgical Pathology. PMID 28863076 DOI: 10.1097/Pas.0000000000000939  0.372
2017 Hyams JS, Kugathasan S, Dubinsky MC. Combination Therapy in Pediatric Inflammatory Bowel Disease: Yes, No, Maybe. Inflammatory Bowel Diseases. PMID 28837525 DOI: 10.1097/MIB.0000000000001206  0.329
2017 Marigorta UM, Denson LA, Hyams JS, Mondal K, Prince J, Walters TD, Griffiths A, Noe JD, Crandall WV, Rosh JR, Mack DR, Kellermayer R, Heyman MB, Baker SS, Stephens MC, ... ... Kugathasan S, et al. Transcriptional risk scores link GWAS to eQTLs and predict complications in Crohn's disease. Nature Genetics. PMID 28805827 DOI: 10.1038/Ng.3936  0.445
2017 Santha SL, Shankar PR, Pan A, Schoen B, Kugathasan S, Sauer CG. Mucosal Healing in Clinical Practice: A Single-Center Pediatric IBD Experience. Inflammatory Bowel Diseases. PMID 28644180 DOI: 10.1097/Mib.0000000000001176  0.445
2017 Okou DT, Brant SR, Simpson CL, Haritunians T, Huang C, McGovern DPB, Kugathasan S. Reply. Gastroenterology. PMID 28482170 DOI: 10.1053/j.gastro.2017.05.006  0.592
2017 Gevers D, Kugathasan S, Knights D, Kostic AD, Knight R, Xavier RJ. A Microbiome Foundation for the Study of Crohn's Disease. Cell Host & Microbe. 21: 301-304. PMID 28279336 DOI: 10.1016/J.Chom.2017.02.012  0.429
2017 Mondal K, Kugathasan S. IBD: Genetic differences in Crohn's disease susceptibility and outcome. Nature Reviews. Gastroenterology & Hepatology. PMID 28270696 DOI: 10.1038/Nrgastro.2017.24  0.469
2017 Kugathasan S, Denson LA, Walters TD, Kim MO, Marigorta UM, Schirmer M, Mondal K, Liu C, Griffiths A, Noe JD, Crandall WV, Snapper S, Rabizadeh S, Rosh JR, Shapiro JM, et al. Prediction of complicated disease course for children newly diagnosed with Crohn's disease: a multicentre inception cohort study. Lancet (London, England). PMID 28259484 DOI: 10.1016/S0140-6736(17)30317-3  0.417
2017 Hyams JS, Dubinsky MC, Baldassano RN, Colletti RB, Cucchiara S, Escher J, Faubion W, Fell J, Gold BD, Griffiths A, Koletzko S, Kugathasan S, Markowitz J, Ruemmele FM, Veereman G, et al. Infliximab not Associated With Increased Risk of Malignancy or Hemophagocytic Lymphohistiocytosis in Pediatric Patients With Inflammatory Bowel Disease. Gastroenterology. PMID 28193515 DOI: 10.1053/J.Gastro.2017.02.004  0.426
2017 Rosen MJ, Karns R, Vallance JE, Bezold R, Waddell A, Collins MH, Haberman Y, Minar P, Baldassano RN, Hyams JS, Baker SS, Kellermayer R, Noe JD, Griffiths AM, Rosh JR, ... ... Kugathasan S, et al. Mucosal Expression of Type 2 and Type 17 Immune Response Genes Distinguishes Ulcerative Colitis From Colon-only Crohn's Disease in Treatment-naïve Pediatric Patients. Gastroenterology. PMID 28132889 DOI: 10.1053/J.Gastro.2017.01.016  0.448
2017 Kugathasan S, Denson L, Walters T, Kim MO, Marigorta U, Schirmer M, Mondal K, Liu C, Stephens M, Baldassano R, Markowitz J, Xavier R, Aronow B, Gibson G, Hyams J, et al. O-002 Predicting a Complicated Course for Children Newly Diagnosed with Crohn's Disease: A Multicenter Inception Cohort Study. Inflammatory Bowel Diseases. 23: S1. PMID 28125550 DOI: 10.1097/01.MIB.0000512512.23221.2f  0.314
2017 Chandrakasan S, Venkateswaran S, Kugathasan S. Nonclassic Inflammatory Bowel Disease in Young Infants: Immune Dysregulation, Polyendocrinopathy, Enteropathy, X-Linked Syndrome, and Other Disorders. Pediatric Clinics of North America. 64: 139-160. PMID 27894441 DOI: 10.1016/J.Pcl.2016.08.010  0.367
2017 Bamidele AO, Svingen P, Ramos GP, Sagstetter M, Sarmento OF, Gonzalez M, Lomberk G, Urrutia R, Kugathasan S, Faubion W. Disruption of Epigenetic Pathways in Regulatory T Cells by FOXP3 Mutations and Pro-Inflammatory Signals During Inflammatory Bowel Disease Gastroenterology. 152: S981-S982. DOI: 10.1016/S0016-5085(17)33324-3  0.375
2017 Weitzner J, Ballengee CR, Sauer CG, Venkateswaran S, Prince J, Dodd A, Le K, Chopra P, Kugathasan S. Oral and Fecal Microbiome Characteristics in Treatment Naïve Pediatric IBD Patients Over Time: a Prospective Longitudinal Study Gastroenterology. 152: S961. DOI: 10.1016/S0016-5085(17)33262-6  0.315
2017 Denson LA, Davis S, Mack DR, Boyle BM, Griffiths AM, Leleiko NS, Sauer CG, Keljo DJ, Markowitz J, Baker SS, Rosh JR, Baldassano RN, Patel AS, Pfefferkorn MD, Otley A, ... ... Kugathasan S, et al. Predicting Response to Oral Corticosteroid Induction Therapy in Children Newly Diagnosed with Moderately Active Ulcerative Colitis: The Protect Study Gastroenterology. 152: S957-S958. DOI: 10.1016/S0016-5085(17)33252-3  0.311
2017 Denson LA, Davis S, Mack DR, Boyle BM, Griffiths AM, Leleiko NS, Sauer CG, Keljo DJ, Markowitz J, Baker SS, Rosh JR, Baldassano RN, Patel AS, Pfefferkorn MD, Otley A, ... ... Kugathasan S, et al. Predicting Response to Mesalamine Induction Therapy in Children Newly Diagnosed with Mild-to-Moderate Ulcerative Colitis: The Protect Study Gastroenterology. 152: S956-S957. DOI: 10.1016/S0016-5085(17)33251-1  0.308
2017 Ballengee CR, Prince J, Baldassano RN, Denson LA, Katz J, Cross RK, Patel AS, Quiros A, Tomer G, Kugathasan S. Procollagen III N-Terminal Propeptide (PIIINP) as a Circulating Biomarker for Active Stricture Development in Pediatric Crohn's Disease Gastroenterology. 152: S956. DOI: 10.1016/S0016-5085(17)33250-X  0.384
2017 Denson LA, Jurickova I, Shaw K, Linn A, Dodd A, Okou D, Chalk C, Bonkowski E, Griffiths AM, Baldassano RN, Noe JD, Hyams JS, Crandall WV, Heyman MB, Snapper SB, ... ... Kugathasan S, et al. Low Neutrophil Reactive Oxygen Species Production is Associated with Nicotinamide-Adenine Dinucleotide Phosphate (NADPH) Oxidase Gene Mutations and Refractory Colonic Involvement in Pediatric Crohn Disease Gastroenterology. 152: S955. DOI: 10.1016/S0016-5085(17)33247-X  0.694
2017 Denson LA, Jurickova I, Shaw K, Linn A, Dodd A, Okou D, Chalk C, Bonkowski E, Griffiths AM, Baldassano RN, Noe JD, Hyams JS, Crandall WV, Heyman MB, Snapper SB, ... ... Kugathasan S, et al. Reduced Neutrophil Granulocyte-Macrophage Colony Stimulating Factor Signaling is Associated with Granulocyte-Macrophage Colony Stimulating Factor Receptor Alpha Chain Gene Mutations and Stricturing Disease Complications in Pediatric Crohn Disease Gastroenterology. 152: S955. DOI: 10.1016/S0016-5085(17)33246-8  0.703
2017 Prince J, Venkateswaran S, Cutler DJ, Okou D, Chopra P, Davis S, Baker SS, Strople JA, Hommel KA, Evans JS, Sauer CG, Markowitz J, Rufo PA, Pfefferkorn MD, Ziring D, ... ... Kugathasan S, et al. Greater Contribution of HLA to Risk for Pediatric-Onset Ulcerative Colitis Can be Narrowed to 3 Independent Classic HLA Variants and Corresponding Amino Acid Changes Gastroenterology. 152: S954. DOI: 10.1016/S0016-5085(17)33244-4  0.674
2017 Townsend P, Davis S, Mack DR, Boyle BM, Griffiths AM, Leleiko NS, Sauer CG, Keljo DJ, Markowitz J, Baker SS, Rosh JR, Baldassano RN, Patel AS, Pfefferkorn MD, Otley A, ... ... Kugathasan S, et al. Is Mesalamine Monotherapy Equally Effective in Inducing Remission in Mild Versus Moderate Pediatric Ulcerative Colitis at Diagnosis? Gastroenterology. 152: S953. DOI: 10.1016/S0016-5085(17)33242-0  0.337
2017 Hyams JS, Davis S, Mack DR, Boyle BM, Griffiths AM, Leleiko NS, Sauer CG, Keljo DJ, Markowitz J, Baker SS, Rosh JR, Baldassano RN, Patel AS, Pfefferkorn MD, Otley A, ... ... Kugathasan S, et al. Predicting Non-Response to Intravenous Corticosteroid Induction Therapy in Children Newly Diagnosed with Severely Active Ulcerative Colitis: The Protect Study Gastroenterology. 152: S202. DOI: 10.1016/S0016-5085(17)30981-2  0.311
2017 Hyams JS, Davis S, Mack DR, Boyle BM, Griffiths AM, Leleiko NS, Sauer CG, Keljo DJ, Markowitz J, Baker SS, Rosh JR, Baldassano RN, Patel AS, Pfefferkorn MD, Otley A, ... ... Kugathasan S, et al. Suboptimal Early Outcomes following Standardized Induction Therapy in Children Newly Diagnosed with Ulcerative Colitis: The Protect Study Gastroenterology. 152: S201. DOI: 10.1016/S0016-5085(17)30979-4  0.304
2017 Schirmer M, Vlamakis H, Denson LA, Davis S, Rufo PA, Baker SS, Strople JA, Sauer CG, Markowitz J, Pfefferkorn MD, Ziring D, Oliva-Hemker M, Sudel B, Rosh JR, Otley A, ... ... Kugathasan S, et al. Microbial Dysbiosis Associated with Disease Severity in Treatment Naive Pediatric Patients with New-Onset Ulcerative Colitis Gastroenterology. 152: S172-S173. DOI: 10.1016/S0016-5085(17)30894-6  0.439
2017 Kugathasan S, Denson LA, Walters TD, Kim M, Marigorta U, Schirmer M, Mondal K, Liu C, Griffiths AM, Noe JD, Crandall WV, Snapper SB, Rabizadeh S, Rosh JR, Shapiro JM, et al. Early Anti-TNF is Effective in Preventing Internal Penetrating but not Stricturing Disease Complications in Children Newly Diagnosed with Crohn's Disease: A Prospective Risk Prediction Model for Disease Behavior Study Gastroenterology. 152: S64. DOI: 10.1016/S0016-5085(17)30569-3  0.462
2016 Hofmekler T, Bertha M, McCracken C, Martineau B, McKinnon E, Schoen BT, McElhanon BO, Tenjarla G, Kugathasan S, Sauer C. Infliximab Optimization Based on Therapeutic Drug Monitoring in Pediatric IBD. Journal of Pediatric Gastroenterology and Nutrition. PMID 28079601 DOI: 10.1097/Mpg.0000000000001302  0.381
2016 Brant SR, Okou DT, Simpson CL, Cutler DJ, Haritunians T, Bradfield JP, Chopra P, Prince J, Begum F, Kumar A, Huang C, Venkateswaran S, Datta LW, Wei Z, Thomas K, ... ... Kugathasan S, et al. Genome-wide Association Study Identifies African-Specific Susceptibility Loci in African Americans with Inflammatory Bowel Disease. Gastroenterology. PMID 27693347 DOI: 10.1053/J.Gastro.2016.09.032  0.763
2016 Rivas MA, Graham D, Sulem P, Stevens C, Desch AN, Goyette P, Gudbjartsson D, Jonsdottir I, Thorsteinsdottir U, Degenhardt F, Mucha S, Kurki MI, Li D, D'Amato M, Annese V, ... ... Kugathasan S, et al. A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis. Nature Communications. 7: 12342. PMID 27503255 DOI: 10.1038/Ncomms12342  0.378
2016 Li D, Achkar JP, Haritunians T, Jacobs JP, Hui KY, D'Amato M, Brand S, Radford-Smith G, Halfvarson J, Niess JH, Kugathasan S, Büning C, Schumm LP, Klei L, Ananthakrishnan A, et al. A pleiotropic missense variant in SLC39A8 is associated with Crohn's disease and human gut microbiome composition. Gastroenterology. PMID 27492617 DOI: 10.1053/J.Gastro.2016.06.051  0.511
2016 Syed S, Kugathasan S, Kumar A, Prince J, Schoen BT, McCracken C, Ziegler TR, Suchdev PS. Use of Reticulocyte Hemoglobin Content in the Assessment of Iron Deficiency in Children with Inflammatory Bowel Disease. Journal of Pediatric Gastroenterology and Nutrition. PMID 27429427 DOI: 10.1097/Mpg.0000000000001335  0.313
2016 Shaw KA, Bertha M, Hofmekler T, Chopra P, Vatanen T, Srivatsa A, Prince J, Kumar A, Sauer C, Zwick ME, Satten GA, Kostic AD, Mulle JG, Xavier RJ, Kugathasan S. Dysbiosis, inflammation, and response to treatment: a longitudinal study of pediatric subjects with newly diagnosed inflammatory bowel disease. Genome Medicine. 8: 75. PMID 27412252 DOI: 10.1186/S13073-016-0331-Y  0.348
2016 Dhere T, Copland I, Garcia M, Chiang KY, Chinnadurai R, Prasad M, Galipeau J, Kugathasan S. Randomised clinical trial: safety of autologous and metabolically fit bone marrow mesenchymal stromal cells in medically refractory Crohn's disease - a phase 1 trial with three doses. Alimentary Pharmacology & Therapeutics. PMID 27385373 DOI: 10.1111/Apt.13717  0.33
2016 Chuang LS, Villaverde N, Hui KY, Mortha A, Rahman A, Levine AP, Haritunians T, Ng SM, Zhang W, Hsu NY, Facey JA, Luong T, Fernandez-Hernandez H, Li D, Rivas M, ... ... Kugathasan S, et al. A Frameshift in CSF2RB Predominant Among Ashkenazi Jews Increases Risk for Crohn's Disease and Reduces Monocyte Signaling via GMCSF. Gastroenterology. PMID 27377463 DOI: 10.1053/J.Gastro.2016.06.045  0.357
2016 Romano C, Syed S, Valenti S, Kugathasan S. Management of Acute Severe Colitis in Children With Ulcerative Colitis in the Biologics Era. Pediatrics. 137. PMID 27244779 DOI: 10.1542/Peds.2015-1184  0.363
2016 Palle SK, Prasad M, Kugathasan S. Approach to a Child with Colitis. Indian Journal of Pediatrics. PMID 27080713 DOI: 10.1007/S12098-016-2091-5  0.399
2016 Schwerd T, Pandey S, Yang HT, Bagola K, Jameson E, Jung J, Lachmann RH, Shah N, Patel SY, Booth C, Runz H, Düker G, Bettels R, Rohrbach M, Kugathasan S, et al. Impaired antibacterial autophagy links granulomatous intestinal inflammation in Niemann-Pick disease type C1 and XIAP deficiency with NOD2 variants in Crohn's disease. Gut. PMID 26953272 DOI: 10.1136/Gutjnl-2015-310382  0.409
2016 Yusung S, Kugathasan S, Udell J, Lin L, Braun J. Su1860 Cytomegalovirus Infection Enhances Susceptibility to Crohn's Disease in Individuals With KIR and HLA Pairs Enabling NK Cell Licensing Gastroenterology. 150: S572-S573. DOI: 10.1016/S0016-5085(16)31959-X  0.349
2016 Hyams JS, Dubinsky M, Davis S, Walters TD, Mack DR, Boyle B, Griffiths AM, Leleiko NS, Sauer C, Keljo DJ, Markowitz J, Baker SS, Rosh JR, Baldassano RN, Oliva-Hemker M, ... ... Kugathasan S, et al. 634 Serologic Reactivity Reflects Clinical and Genetic Expression of Ulcerative Colitis in Children. The Protect Study Gastroenterology. 150: S133. DOI: 10.1016/S0016-5085(16)30548-0  0.332
2016 Hyams JS, Dubinsky M, Baldassano RN, Colletti RB, Cucchiara S, Escher J, Faubion W, Fell J, Gold BD, Griffiths AM, Koletzko S, Kugathasan S, Markowitz J, Ruemmele F, Veereman G, et al. 629 Risk of Malignancy in Pediatric Inflammatory Bowel Disease: Results From the DEVELOP Registry Gastroenterology. 150. DOI: 10.1016/S0016-5085(16)30543-1  0.445
2016 Dhere T, Copland I, Chiang K, Garcia M, Chinnadurai R, Chikkabbagilu M, Galipeau J, Kugathasan S. Safety and Efficacy of Autologous and Metabolically Fit Bone Marrow Mesenchymal Stromal Cells (BM-MSC) in Medically Refractory Crohn's Disease (CD) Cytotherapy. 18: S12. DOI: 10.1016/J.Jcyt.2016.03.030  0.381
2015 Sunseri WM, Kugathasan S, Keljo DJ, Greer JB, Ranganathan S, Cross RK, Siegel CA, Regueiro MD. IBD LIVE Case Series-Case 3: Very Early-Onset Inflammatory Bowel Disease: When Genetic Testing Proves Beneficial. Inflammatory Bowel Diseases. 21: 2958-68. PMID 26583935 DOI: 10.1097/Mib.0000000000000650  0.406
2015 Sauer CG, Middleton JP, McCracken C, Loewen J, Braithwaite K, Alazraki A, Martin DR, Kugathasan S. Magnetic Resonance Enterography (MRE) Healing and MRE Remission Predicts Improved Outcome in Pediatric Crohn Disease. Journal of Pediatric Gastroenterology and Nutrition. PMID 26348683 DOI: 10.1097/Mpg.0000000000000976  0.394
2015 Li YR, Li J, Zhao SD, Bradfield JP, Mentch FD, Maggadottir SM, Hou C, Abrams DJ, Chang D, Gao F, Guo Y, Wei Z, Connolly JJ, Cardinale CJ, Bakay M, ... ... Kugathasan S, et al. Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases. Nature Medicine. 21: 1018-27. PMID 26301688 DOI: 10.1038/Nm.3933  0.407
2015 Huang C, Haritunians T, Okou DT, Cutler DJ, Zwick ME, Taylor KD, Datta LW, Maranville JC, Liu Z, Ellis S, Chopra P, Alexander JS, Baldassano RN, Cross RK, Dassopoulos T, ... ... Kugathasan S, et al. Characterization of Genetic Loci That Affect Susceptibility to Inflammatory Bowel Diseases in African Americans. Gastroenterology. PMID 26278503 DOI: 10.1053/J.Gastro.2015.07.065  0.708
2015 McGovern DP, Kugathasan S, Cho JH. Genetics of Inflammatory Bowel Diseases. Gastroenterology. 149: 1163-1176.e2. PMID 26255561 DOI: 10.1053/j.gastro.2015.08.001  0.3
2015 Simek RZ, Prince J, Syed S, Sauer CG, Martineau B, Hofmekler T, Freeman AJ, Kumar A, McElhanon BO, Schoen BT, Tenjarla G, McCracken C, Ziegler TR, Tangpricha V, Kugathasan S. Pilot Study Evaluating Efficacy of two Regimens for Hypovitaminosis D Repletion in Pediatric Inflammatory Bowel Disease. Journal of Pediatric Gastroenterology and Nutrition. PMID 26196201 DOI: 10.1097/Mpg.0000000000000915  0.341
2015 Cutler DJ, Zwick ME, Okou DT, Prahalad S, Walters T, Guthery SL, Dubinsky M, Baldassano R, Crandall WV, Rosh J, Markowitz J, Stephens M, Kellermayer R, Pfefferkorn M, Heyman MB, ... ... Kugathasan S, et al. Dissecting Allele Architecture of Early Onset IBD Using High-Density Genotyping. Plos One. 10: e0128074. PMID 26098103 DOI: 10.1371/Journal.Pone.0128074  0.742
2015 Ning K, Gettler K, Zhang W, Ng SM, Bowen BM, Hyams J, Stephens MC, Kugathasan S, Denson LA, Schadt EE, Hoffman GE, Cho JH. Improved integrative framework combining association data with gene expression features to prioritize Crohn's disease genes. Human Molecular Genetics. 24: 4147-57. PMID 25935003 DOI: 10.1093/Hmg/Ddv142  0.388
2015 Chinnadurai R, Copland IB, Ng S, Garcia M, Prasad M, Arafat D, Gibson G, Kugathasan S, Galipeau J. Mesenchymal Stromal Cells Derived From Crohn's Patients Deploy Indoleamine 2,3-dioxygenase-mediated Immune Suppression, Independent of Autophagy. Molecular Therapy : the Journal of the American Society of Gene Therapy. 23: 1248-61. PMID 25899824 DOI: 10.1038/Mt.2015.67  0.338
2015 Haberman Y, Tickle TL, Dexheimer PJ, Kim MO, Tang D, Karns R, Baldassano RN, Noe JD, Rosh J, Markowitz J, Heyman MB, Griffiths AM, Crandall WV, Mack DR, Baker SS, ... ... Kugathasan S, et al. Corrigendum. Pediatric Crohn disease patients exhibit specific ileal transcriptome and microbiome signature. The Journal of Clinical Investigation. 125: 1363. PMID 25729854 DOI: 10.1172/Jci79657  0.455
2015 Natarajan B, Sauer C, Shehata B, Kugathasan S. Hidradenitis suppurativa and pediatric Crohn disease. Journal of Pediatric Gastroenterology and Nutrition. 60: e29-30. PMID 24121140 DOI: 10.1097/Mpg.0000000000000185  0.483
2015 Mack DR, Saul B, Davis S, Marquis A, Boyle B, Griffiths AM, Sauer C, Markowitz J, Leleiko NS, Rosh JR, Keljo DJ, Baker SS, Pfefferkorn MD, Heyman MB, Patel AS, ... ... Kugathasan S, et al. Su1195 Simple Blood Testing Defines Severe New Onset Ulcerative Colitis in Children: The PROTECT Study Gastroenterology. 148: S-433-S-434. DOI: 10.1016/S0016-5085(15)31466-9  0.304
2015 Walters TD, Mack DR, Boyle B, Griffiths AM, Sauer C, Leleiko NS, Markowitz J, Keljo DJ, Rosh JR, Baker SS, Heyman MB, Patel AS, Pfefferkorn MD, Baldassano R, Noe JD, ... ... Kugathasan S, et al. Sa1999 Patient Related Outcomes and Disease Activity Indices in New Onset Pediatric Ulcerative Colitis: The PROTECT Study Gastroenterology. 148: S-380. DOI: 10.1016/S0016-5085(15)31273-7  0.334
2015 Brant SR, Huang C, Haritunians T, Okou DT, Cutler DJ, Zwick ME, Datta LW, Taylor KD, Rotter JI, Bridges S, Kimberly RP, Rich SS, McGovern D, Kugathasan S. 387 Immunochip Implicates Multiple Genetic Loci for African American IBD Including HLA-DRB1*1502 for UC, NOD2, PTGER4, IL23R, LZKF3 and STAT5A/STAT3 for CD and Several Regions of Significant Admixture Linkage Disequilibrium Gastroenterology. 148: S-80. DOI: 10.1016/S0016-5085(15)30281-X  0.707
2015 Chinnadurai R, Copland IB, Ng S, Garcia M, Arafat D, Gibson G, Kugathasan S, Galipeau J. Marrow mesenchymal stromal cells derived from subjects with Crohn’s Disease deploy IDO mediated immune suppression, independent of autophagy process Cytotherapy. 17: S43. DOI: 10.1016/J.Jcyt.2015.03.457  0.309
2014 Okou DT, Kugathasan S. Role of genetics in pediatric inflammatory bowel disease. Inflammatory Bowel Diseases. 20: 1878-84. PMID 25118609 DOI: 10.1097/Mib.0000000000000085  0.747
2014 Okou DT, Mondal K, Faubion WA, Kobrynski LJ, Denson LA, Mulle JG, Ramachandran D, Xiong Y, Svingen P, Patel V, Bose P, Waters JP, Prahalad S, Cutler DJ, Zwick ME, ... Kugathasan S, et al. Exome sequencing identifies a novel FOXP3 mutation in a 2-generation family with inflammatory bowel disease. Journal of Pediatric Gastroenterology and Nutrition. 58: 561-8. PMID 24792626 DOI: 10.1097/Mpg.0000000000000302  0.723
2014 Minar P, Haberman Y, Jurickova I, Wen T, Rothenberg ME, Kim MO, Saeed SA, Baldassano RN, Stephens M, Markowitz J, Rosh J, Crandall WV, Heyman MB, Mack DR, Griffiths AM, ... ... Kugathasan S, et al. Utility of neutrophil Fcγ receptor I (CD64) index as a biomarker for mucosal inflammation in pediatric Crohn's disease. Inflammatory Bowel Diseases. 20: 1037-48. PMID 24788216 DOI: 10.1097/Mib.0000000000000049  0.457
2014 Gevers D, Kugathasan S, Denson LA, Vázquez-Baeza Y, Van Treuren W, Ren B, Schwager E, Knights D, Song SJ, Yassour M, Morgan XC, Kostic AD, Luo C, González A, McDonald D, et al. The treatment-naive microbiome in new-onset Crohn's disease. Cell Host & Microbe. 15: 382-92. PMID 24629344 DOI: 10.1016/J.Chom.2014.02.005  0.48
2014 Bicette R, Tenjarla G, Kugathasan S, Alazraki A, Haddad L. A 14-year-old girl with recurrent vulvar abscess. Journal of Pediatric and Adolescent Gynecology. 27: e83-6. PMID 24268555 DOI: 10.1016/J.Jpag.2013.07.010  0.346
2014 Walters TD, Kim MO, Denson LA, Griffiths AM, Dubinsky M, Markowitz J, Baldassano R, Crandall W, Rosh J, Pfefferkorn M, Otley A, Heyman MB, LeLeiko N, Baker S, Guthery SL, ... ... Kugathasan S, et al. Increased effectiveness of early therapy with anti-tumor necrosis factor-α vs an immunomodulator in children with Crohn's disease. Gastroenterology. 146: 383-91. PMID 24162032 DOI: 10.1053/J.Gastro.2013.10.027  0.386
2014 Dubinsky M, Cucchiara S, Escher JC, Faubion WA, Fell J, Gold BD, Griffiths AM, Hyams JS, Koletzko S, Kugathasan S, Veereman G, Winter H, Colletti RB, Baldassano R, Ruemmele F, et al. Su1391 Infliximab Therapy in Pediatric Crohn's Disease: Results From Develop, A Multicenter Prospective Inflammatory Bowel Disease Registry Gastroenterology. 146: S-456. DOI: 10.1016/S0016-5085(14)61634-6  0.494
2014 Hofmekler T, Bertha M, McCracken C, McKinnon E, Kugathasan S, Sauer C. Su1100 Determinants of Immunogenicity in Children With Inflammatory Bowel Disease Receiving Infliximab Gastroenterology. 146: S-374. DOI: 10.1016/S0016-5085(14)61349-4  0.442
2014 Markowitz J, Lerer T, Morganstern J, Deslandres C, Tomer G, Schaefer M, Kugathasan S, Faubion WA, Kappelman M, Sudel B, Hitch M, Keljo DJ, Grossman AB, Carvalho R, Leleiko NS, et al. 961 Long-Term Outcome of Children With Crohn's Disease: Results From a Large Multi-Center North American Inception Cohort Gastroenterology. 146: S-170-S-171. DOI: 10.1016/S0016-5085(14)60603-X  0.378
2014 Gevers D, Kugathasan S, Denson L, Vázquez-Baeza Y, Van Treuren W, Ren B, Schwager E, Knights D, Song SJ, Yassour M, Morgan X, Kostic AD, Luo C, Gonzalez A, McDonald D, et al. 850a The treatment-naive microbiome in early-onset Crohn's Disease Gastroenterology. 146: S-144. DOI: 10.1016/S0016-5085(14)60512-6  0.36
2014 Haberman Y, Tickle TL, Dexheimer PJ, Huttenhower C, Karns R, Baldassano R, Noe JD, Rosh JR, Markowitz J, Heyman MB, Griffiths AM, Crandall W, Mack DR, Baker SS, Hyams JS, ... Kugathasan S, et al. 78 Host Ileal APOA1 and DUOX2 Co-Expression Modules Are Associated With Microbial Shifts and Clinical Outcomes in Treatment Naive Pediatric Crohn Disease Gastroenterology. 146: S-22. DOI: 10.1016/S0016-5085(14)60078-0  0.369
2013 Middleton JP, Bhagavathula AP, Gaye B, Alvarez JA, Huang CS, Sauer CG, Tenjarla G, Schoen BT, Kumar A, Prasad M, Okou DT, Ifeadike WC, Dhere TA, Conneely KN, Ziegler TR, ... ... Kugathasan S, et al. Vitamin D status and bone mineral density in African American children with Crohn disease. Journal of Pediatric Gastroenterology and Nutrition. 57: 587-93. PMID 23760229 DOI: 10.1097/Mpg.0B013E31829E0B89  0.675
2013 Waters J, Dhere V, Benjamin A, Sekar A, Kumar A, Prahalad S, Okou DT, Kugathasan S. A practical and novel method to extract genomic DNA from blood collection kits for plasma protein preservation. Journal of Visualized Experiments : Jove. e4241. PMID 23711730 DOI: 10.3791/4241  0.638
2013 Kunde S, Pham A, Bonczyk S, Crumb T, Duba M, Conrad H, Cloney D, Kugathasan S. Safety, tolerability, and clinical response after fecal transplantation in children and young adults with ulcerative colitis. Journal of Pediatric Gastroenterology and Nutrition. 56: 597-601. PMID 23542823 DOI: 10.1097/Mpg.0B013E318292Fa0D  0.323
2013 Adamiak T, Walkiewicz-Jedrzejczak D, Fish D, Brown C, Tung J, Khan K, Faubion W, Park R, Heikenen J, Yaffee M, Rivera-Bennett MT, Wiedkamp M, Stephens M, Noel R, Nugent M, ... ... Kugathasan S, et al. Incidence, clinical characteristics, and natural history of pediatric IBD in Wisconsin: a population-based epidemiological study. Inflammatory Bowel Diseases. 19: 1218-23. PMID 23528339 DOI: 10.1097/MIB.0b013e318280b13e  0.326
2013 Huang A, Huang C, Kugathasan S. Vertebral osteomyelitis due to Candida parapsilosis in a child with Crohn disease while receiving anti-TNF therapy. Journal of Pediatric Gastroenterology and Nutrition. 56: e23-6. PMID 23201701 DOI: 10.1097/Mpg.0B013E31827Ecbda  0.383
2013 Moran CJ, Walters TD, Guo CH, Kugathasan S, Klein C, Turner D, Wolters VM, Bandsma RH, Mouzaki M, Zachos M, Langer JC, Cutz E, Benseler SM, Roifman CM, Silverberg MS, et al. IL-10R polymorphisms are associated with very-early-onset ulcerative colitis. Inflammatory Bowel Diseases. 19: 115-23. PMID 22550014 DOI: 10.1002/Ibd.22974  0.362
2013 Colletti R, Cucchiara S, Dubinsky M, Escher J, Faubion W, Fell J, Gold B, Griffiths A, Hyams J, Koletzko S, Kugathasan S, Winter H, Baldassano R, Markowitz J, Ruemmele F, et al. P436 Malignancies in children receiving infliximab and other inflammatory bowel disease therapies: an inflammatory bowel disease multicenter, prospective, long-term registry of pediatric patients (DEVELOP) registry data Journal of Crohn's and Colitis. 7: S184-S185. DOI: 10.1016/S1873-9946(13)60457-2  0.46
2013 Baldassano R, Colletti RB, Cucchiara S, Dubinsky M, Escher JC, Faubion WA, Fell J, Gold BD, Griffiths AM, Hyams JS, Koletzko S, Kugathasan S, Markowitz J, Ruemmele F, Veereman G, et al. 41 Serious Infections and Associated Risk Factors in Patients Receiving Infliximab and Immunotherapies for Children With Inflammatory Bowel Disease: Develop Registry Data Gastroenterology. 144: S-11. DOI: 10.1016/S1873-9946(13)60016-1  0.419
2013 Baldassano R, Colletti R, Cucchiara S, Dubinsky M, Escher J, Faubion W, Fell J, Gold B, Griffiths A, Hyams J, Koletzko S, Kugathasan S, Markowitz J, Ruemmele F, Veereman G, et al. 15 Serious infections and associated risk factors in patients receiving infliximab and immunotherapies for children with inflammatory bowel disease: DEVELOP registry data Journal of Crohn's and Colitis. 7: S7-S8. DOI: 10.1016/S1873-9946(13)60016-1  0.304
2013 Minar P, Jurickova I, Haberman Y, Kim M, Saeed SA, Hyams JS, Heyman MB, Kugathasan S, Denson L. Tu1940 Neutrophil FCy Receptor 1 (CD64) Index As a Non-Invasive Biomarker for Clinical and Mucosal Disease Activity in Pediatric Inflammatory Bowel Disease Gastroenterology. 144: S-886. DOI: 10.1016/S0016-5085(13)63296-5  0.468
2013 Kugathasan S, Okou DT, Mondal K, Benjamin AL, Kumar A, Hussain SZ, Katz J, Cross R, Moulton DE, Cutler DJ, Zwick ME. Su1743 Exome Sequencing Identify Novel Variants in African-Americans With Severe Perianal and Colonic Crohn's Disease Gastroenterology. 144: S-465. DOI: 10.1016/S0016-5085(13)61720-5  0.696
2013 Kugathasan S, Dubinsky M, Guthery SL, Okou DT, Bose P, Zwick ME, Cutler DJ, Waters JP, Hyams JS, Baldassano R, Stephens MC, Heyman MB, Griffiths AM, Crandall W, Markowitz J, et al. 976 Early Onset Crohn's Disease Exhibit Distinct Allele Architecture Differences and Reveal New IBD Loci Gastroenterology. 144: S-178. DOI: 10.1016/S0016-5085(13)60634-4  0.735
2013 Haberman Y, Dexheimer PJ, Karns R, Tang D, Fey B, Bonkowski EL, Griffiths AM, Hyams JS, Kugathasan S, Ziring D, Evans J, Baker SS, Mack DR, Moulton DE, Keljo DJ, et al. 834 Ileal Transcriptome Analysis Reveals Mucosal Immune Maturation With Increasing Age-of-Onset in Pediatric Crohn Disease and Healthy Controls - A Mucosal Gene Expression Based Signature That Supports the Paris Classification for Age-of-Onset Gastroenterology. 144: S-147-S-148. DOI: 10.1016/S0016-5085(13)60529-6  0.397
2013 Colletti RB, Cucchiara S, Dubinsky M, Escher JC, Faubion WA, Fell J, Gold BD, Griffiths AM, Hyams JS, Koletzko S, Kugathasan S, Winter HS, Baldassano R, Markowitz J, Ruemmele F, et al. 833 Malignancies in Children Receiving Infliximab and Other Inflammatory Bowel Disease Therapies: An Inflammatory Bowel Disease Multicenter, Prospective, Long-Term Registry of Pediatric Patients (Develop) Registry Data Gastroenterology. 144: S-147. DOI: 10.1016/S0016-5085(13)60528-4  0.356
2013 Hyams JS, Kim M, Denson L, Griffiths AM, Dubinsky M, Markowitz J, Baldassano R, Crandall W, Rosh JR, Pfefferkorn MD, Otley AR, Heyman MB, Leleiko NS, Baker SS, Guthery SL, ... ... Kugathasan S, et al. 829 Early Anti-TNFα Therapy Is Superior to Early Immunomodulator Therapy in Newly Diagnosed Children With Crohn's Disease Gastroenterology. 144: S-146. DOI: 10.1016/S0016-5085(13)60524-7  0.373
2012 Rieder F, Kugathasan S. Circulating antibodies against bacterial wall products: are there arguments for early immunosuppression? Digestive Diseases (Basel, Switzerland). 30: 55-66. PMID 23295693 DOI: 10.1159/000342603  0.467
2012 Stremmel W, Ehehalt R, Staffer S, Stoffels S, Mohr A, Karner M, Braun A, Gross V, Nielsen OH, Bjerrum JT, Seidelin JB, Nyberg C, Ainsworth M, Sandborn WJ, Fiocchi C, ... ... Kugathasan S, et al. Dealing with our 'in-vironment': new aspects of inflammatory bowel disease pathogenesis and therapy. Digestive Diseases. 30: 1-1. PMID 23295685 DOI: 10.1159/000342743  0.424
2012 Jostins L, Ripke S, Weersma RK, Duerr RH, McGovern DP, Hui KY, Lee JC, Schumm LP, Sharma Y, Anderson CA, Essers J, Mitrovic M, Ning K, Cleynen I, Theatre E, ... ... Kugathasan S, et al. Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. Nature. 491: 119-24. PMID 23128233 DOI: 10.1038/Nature11582  0.506
2012 Huang C, Kugathasan S. Markers that differentiate early from late IBD. Digestive Diseases (Basel, Switzerland). 30: 380-2. PMID 22796800 DOI: 10.1159/000338130  0.322
2012 Muise AM, Snapper SB, Kugathasan S. The age of gene discovery in very early onset inflammatory bowel disease. Gastroenterology. 143: 285-8. PMID 22727850 DOI: 10.1053/J.Gastro.2012.06.025  0.406
2012 Rosen MJ, Denson LA, Kugathasan S. Commentaries on "Workshop report: developing a pediatric inflammatory bowel diseases network and data platform in Canada": pediatric inflammatory bowel disease networks: raising the bar. Journal of Pediatric Gastroenterology and Nutrition. 55: 121-2. PMID 22659890 DOI: 10.1097/Mpg.0B013E3182605070  0.414
2012 Sauer CG, Middleton JP, Alazraki A, Udayasankar UK, Kalb B, Applegate KE, Martin DR, Kugathasan S. Comparison of magnetic resonance enterography with endoscopy, histopathology, and laboratory evaluation in pediatric Crohn disease. Journal of Pediatric Gastroenterology and Nutrition. 55: 178-84. PMID 22513710 DOI: 10.1097/Mpg.0B013E3182598465  0.438
2012 Adeyanju O, Okou DT, Huang C, Kumar A, Sauer C, Galloway C, Prasad M, Waters J, Cutler DJ, Zwick ME, Dhere T, Kugathasan S. Common NOD2 risk variants in African Americans with Crohn's disease are due exclusively to recent Caucasian admixture. Inflammatory Bowel Diseases. 18: 2357-9. PMID 22447396 DOI: 10.1002/Ibd.22944  0.721
2012 Wang MH, Okazaki T, Kugathasan S, Cho JH, Isaacs KL, Lewis JD, Smoot DT, Valentine JF, Kader HA, Ford JG, Harris ML, Oliva-Hemker M, Cuffari C, Torbenson MS, Duerr RH, et al. Contribution of higher risk genes and European admixture to Crohn's disease in African Americans. Inflammatory Bowel Diseases. 18: 2277-87. PMID 22411504 DOI: 10.1002/Ibd.22931  0.381
2012 Huff CD, Witherspoon DJ, Zhang Y, Gatenbee C, Denson LA, Kugathasan S, Hakonarson H, Whiting A, Davis CT, Wu W, Xing J, Watkins WS, Bamshad MJ, Bradfield JP, Bulayeva K, et al. Crohn's disease and genetic hitchhiking at IBD5. Molecular Biology and Evolution. 29: 101-11. PMID 21816865 DOI: 10.1093/Molbev/Msr151  0.455
2012 Kugathasan S, Dhere TA, Saeed SA, Denson L, Cross R, Landers CJ, McGovern DP, Walters TD, Dubinsky M. Su1914 Unique Antimicrobial and Genetic Profiles in African Americans With Crohn's Disease Suggest Underlying Mechanistic Differences Gastroenterology. 142: S-535. DOI: 10.1016/S0016-5085(12)62053-8  0.378
2012 Sauer CG, Middleton JP, Alazraki A, Kalb B, Applegate K, Martin DR, Kugathasan S. Sa1978 Magnetic Resonance Enterography Detects Response to Treatment in Children With Crohn's Disease Gastroenterology. 142: S-372. DOI: 10.1016/S0016-5085(12)61404-8  0.347
2012 Walters TD, Dubinsky M, Griffiths AM, Baldassano R, Hyams JS, Stephens MC, Markowitz J, Crandall W, Heyman MB, Kellermayer R, Mack DR, Oliva-Hemker M, Patel AS, Kirschner BS, Moulton DE, ... ... Kugathasan S, et al. 140 Anti-Microbial Serology Patterns in 824 Children With Newly Diagnosed Crohn's Disease: Association With GM-CSF Auto-Antibodies and Specific Clinical Phenotypes Gastroenterology. 142: S-36-S-37. DOI: 10.1016/S0016-5085(12)60140-1  0.405
2012 Hyams JS, Kim M, Denson L, Stephens MC, Markowitz J, Griffiths AM, Crandall W, Essers JB, Baldassano R, Dubinsky M, Rosh JR, Pfefferkorn MD, Kim SC, Otley AR, Kellermayer R, ... ... Kugathasan S, et al. 138 Effect of Deep Ulceration at Diagnostic Colonoscopy on Initial Therapy and One Year Outcome in Children With Crohn's Disease Gastroenterology. 142: S-36. DOI: 10.1016/S0016-5085(12)60138-3  0.397
2011 Sauer CG, Kugathasan S, Martin DR, Applegate KE. Medical radiation exposure in children with inflammatory bowel disease estimates high cumulative doses. Inflammatory Bowel Diseases. 17: 2326-32. PMID 21987300 DOI: 10.1002/Ibd.21626  0.335
2011 Biank VF, Sheth MK, Talano J, Margolis D, Simpson P, Kugathasan S, Stephens M. Association of Crohn's disease, thiopurines, and primary epstein-barr virus infection with hemophagocytic lymphohistiocytosis. The Journal of Pediatrics. 159: 808-12. PMID 21722918 DOI: 10.1016/J.Jpeds.2011.04.045  0.434
2011 Kunde S, Prasad M, Kugathasan S. Rising incidence of inflammatory bowel disease in young children: What does the future hold? Journal of Pediatric Gastroenterology and Nutrition. 53: 128. PMID 21637130 DOI: 10.1097/Mpg.0B013E318225Cde5  0.437
2011 Kang J, Kugathasan S, Georges M, Zhao H, Cho JH. Improved risk prediction for Crohn's disease with a multi-locus approach. Human Molecular Genetics. 20: 2435-42. PMID 21427131 DOI: 10.1093/Hmg/Ddr116  0.351
2011 Anderson CA, Boucher G, Lees CW, Franke A, D'Amato M, Taylor KD, Lee JC, Goyette P, Imielinski M, Latiano A, Lagacé C, Scott R, Amininejad L, Bumpstead S, Baidoo L, ... ... Kugathasan S, et al. Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47. Nature Genetics. 43: 246-52. PMID 21297633 DOI: 10.1038/Ng.764  0.439
2011 Hyams J, Walters TD, Crandall W, Kugathasan S, Griffiths A, Blank M, Johanns J, Lang Y, Markowitz J, Cohen S, Winter HS, Veereman-Wauters G, Ferry G, Baldassano R. Safety and efficacy of maintenance infliximab therapy for moderate-to-severe Crohn's disease in children: REACH open-label extension. Current Medical Research and Opinion. 27: 651-62. PMID 21241207 DOI: 10.1185/03007995.2010.547575  0.381
2011 Siegel CA, Siegel LS, Hyams JS, Kugathasan S, Markowitz J, Rosh JR, Leleiko N, Mack DR, Crandall W, Evans J, Keljo DJ, Otley AR, Oliva-Hemker M, Farrior S, Langton CR, et al. Real-time tool to display the predicted disease course and treatment response for children with Crohn's disease. Inflammatory Bowel Diseases. 17: 30-8. PMID 20812335 DOI: 10.1002/Ibd.21386  0.456
2011 Adeyanju O, Okou D, Huang C, Sauer C, Prasad M, Waters J, Ifeadike W, Benjamin A, Labaze S, Cutler D, Zwick M, Dhere T, Kugathasan S. Risk of NOD2 in African-American subjects with Crohnʼs disease is exclusively contributed by Caucasian admixture Inflammatory Bowel Diseases. 17: S77-S78. DOI: 10.1097/00054725-201112002-00255  0.697
2011 Huang C, Medina O, Geem D, Kim W, Kugathasan S, Denning T. VSIG4/Z39Ig, an inhibitory B7 superfamily member, is down-regulated in Intestinal mucosal tissue during Inflammatory Bowel Disease Inflammatory Bowel Diseases. 17: S68-S69. DOI: 10.1097/00054725-201112002-00221  0.39
2011 Dhere T, Hofmeckler T, Griglione N, Huang C, Sauer C, Tenjarla G, Schoen B, Ifeadike W, Olejeme H, Prasad M, Kumar A, Okou D, Galloway C, kugathasan S. Crohnʼs disease is 3 fold higher compared with ulcerative colitis among African-Americans; combined pediatric and adult data from the greater Atlanta area Inflammatory Bowel Diseases. 17: S56. DOI: 10.1097/00054725-201112002-00178  0.712
2011 Sauer CG, Middleton J, Huang C, Kalb B, Martin D, Alazraki A, Applegate K, Kugathasan S. Serial magnetic resonance enterography (MRE) directs clinical decision making in children with small bowel and/or perianal Crohnʼs disease (CD) Inflammatory Bowel Diseases. 17: S55. DOI: 10.1097/00054725-201112002-00176  0.37
2011 Bhagavathula A, Gaye B, Alvarez J, Huang C, Tenjarla G, Sauer C, Schoen B, Prasad M, Waters J, Ifeadike W, Okou D, Ziegler T, Tangprincha V, Kugathasan S. Vitamin D deficiency is found in 2/3 of African American population regardless of underlying IBD or not and the Vitamin D levels are not influenced by disease severity or location in AA population Inflammatory Bowel Diseases. 17: S6. DOI: 10.1097/00054725-201112002-00015  0.666
2011 Anderson CA, Boucher G, Lees CW, Franke A, D'Amato M, Taylor KD, Lee JC, Goyette P, Imielinski M, Latiano A, Lagacé C, Scott R, Amininejad L, Bumpstead S, Baidoo L, ... ... Kugathasan S, et al. Erratum: Corrigendum: Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47 Nature Genetics. 43: 919-919. DOI: 10.1038/Ng0911-919B  0.306
2011 Moran CJ, Kugathasan S, Klein C, Silverberg MS, Muise AM, Snapper SB. Interleukin-10 Receptor Gene Polymorphisms Associate with Early-Onset Inflammatory Bowel Disease Gastroenterology. 140: S-486. DOI: 10.1016/S0016-5085(11)62003-9  0.408
2011 Dubinsky M, Kugathasan S, Kwon S, Haritunians T, Wrobel IT, Wahbeh G, Quiros A, Bahar RJ, Farrior S, Teleten N, Panikkath D, Ippoliti A, Fleshner P, Williams CI, Landers CJ, et al. A Combination of Genetic, Clinical and Immune Markers Predict the Need for Surgery in Crohn's Disease Gastroenterology. 140: S-153. DOI: 10.1016/S0016-5085(11)60621-5  0.373
2010 Franke A, McGovern DP, Barrett JC, Wang K, Radford-Smith GL, Ahmad T, Lees CW, Balschun T, Lee J, Roberts R, Anderson CA, Bis JC, Bumpstead S, Ellinghaus D, Festen EM, ... ... Kugathasan S, et al. Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. Nature Genetics. 42: 1118-25. PMID 21102463 DOI: 10.1038/Ng.717  0.407
2010 Lee JJ, Essers JB, Kugathasan S, Escher JC, Lettre G, Butler JL, Stephens MC, Ramoni MF, Grand RJ, Hirschhorn J. Association of linear growth impairment in pediatric Crohn's disease and a known height locus: a pilot study. Annals of Human Genetics. 74: 489-97. PMID 20846217 DOI: 10.1111/J.1469-1809.2010.00606.X  0.375
2010 Schaefer ME, Machan JT, Kawatu D, Langton CR, Markowitz J, Crandall W, Mack DR, Evans JS, Pfefferkorn MD, Griffiths AM, Otley AR, Bousvaros A, Kugathasan S, Rosh JR, Keljo DJ, et al. Factors that determine risk for surgery in pediatric patients with Crohn's disease. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. 8: 789-94. PMID 20566311 DOI: 10.1016/J.Cgh.2010.05.021  0.417
2010 Dotson JL, Hyams JS, Markowitz J, LeLeiko NS, Mack DR, Evans JS, Pfefferkorn MD, Griffiths AM, Otley AR, Bousvaros A, Kugathasan S, Rosh JR, Keljo D, Carvalho RS, Tomer G, et al. Extraintestinal manifestations of pediatric inflammatory bowel disease and their relation to disease type and severity. Journal of Pediatric Gastroenterology and Nutrition. 51: 140-5. PMID 20453677 DOI: 10.1097/Mpg.0B013E3181Ca4Db4  0.49
2010 Shikhare G, Kugathasan S. Inflammatory bowel disease in children: current trends. Journal of Gastroenterology. 45: 673-82. PMID 20414789 DOI: 10.1007/S00535-010-0241-5  0.427
2010 Turner D, Mack D, Leleiko N, Walters TD, Uusoue K, Leach ST, Day AS, Crandall W, Silverberg MS, Markowitz J, Otley AR, Keljo D, Mamula P, Kugathasan S, Hyams J, et al. Severe pediatric ulcerative colitis: a prospective multicenter study of outcomes and predictors of response. Gastroenterology. 138: 2282-91. PMID 20193683 DOI: 10.1053/J.Gastro.2010.02.047  0.323
2010 Wang K, Baldassano R, Zhang H, Qu HQ, Imielinski M, Kugathasan S, Annese V, Dubinsky M, Rotter JI, Russell RK, Bradfield JP, Sleiman PM, Glessner JT, Walters T, Hou C, et al. Comparative genetic analysis of inflammatory bowel disease and type 1 diabetes implicates multiple loci with opposite effects. Human Molecular Genetics. 19: 2059-67. PMID 20176734 DOI: 10.1093/Hmg/Ddq078  0.463
2010 Sauer CG, Kugathasan S. Pediatric inflammatory bowel disease: highlighting pediatric differences in IBD. The Medical Clinics of North America. 94: 35-52. PMID 19944797 DOI: 10.1016/j.mcna.2009.10.002  0.379
2010 Pasternak BA, D'Mello S, Jurickova II, Han X, Willson T, Flick L, Petiniot L, Uozumi N, Divanovic S, Traurnicht A, Bonkowski E, Kugathasan S, Karp CL, Denson LA. Lipopolysaccharide exposure is linked to activation of the acute phase response and growth failure in pediatric Crohn's disease and murine colitis. Inflammatory Bowel Diseases. 16: 856-69. PMID 19924809 DOI: 10.1002/Ibd.21132  0.394
2010 Greenley RN, Doughty A, Stephens M, Kugathasan S. Brief report: development of the inflammatory bowel disease family responsibility questionnaire. Journal of Pediatric Psychology. 35: 183-7. PMID 19564243 DOI: 10.1093/Jpepsy/Jsp052  0.361
2010 Lee J, Essers J, Kugathasan S, Escher J, Lettre G, Butler J, Stephens M, Ramoni M, Grand R, Hirschhorn J. S03 Association of DYM gene with growth impairment in pediatric Crohn's disease Journal of Crohn's and Colitis Supplements. 4: 19-20. DOI: 10.1016/S1873-9954(10)70030-6  0.39
2010 Parkes M, McGovern DP, Franke A, Vermeire S, Louis E, Ahmad T, Mathew CG, Annese V, Rioux JD, Rotter JI, Dubinsky M, Taylor KD, Kugathasan S, Brant SR, Duerr RH, et al. 847v 18 New Crohn's Disease Susceptibility Genes and Loci Identified by the International IBD Genetics Consortium Gastroenterology. 138: S-115. DOI: 10.1016/S0016-5085(10)60528-8  0.425
2010 Sauer CG, Martin DR, Kugathasan S, Applegate K. 153 Medical Radiation Exposure in Children With Inflammatory Bowel Disease Estimates Potentially Dangerous Cumulative Doses Gastroenterology. 138: S-29-S-30. DOI: 10.1016/S0016-5085(10)60136-9  0.338
2009 Imielinski M, Baldassano RN, Griffiths A, Russell RK, Annese V, Dubinsky M, Kugathasan S, Bradfield JP, Walters TD, Sleiman P, Kim CE, Muise A, Wang K, Glessner JT, Saeed S, et al. Common variants at five new loci associated with early-onset inflammatory bowel disease. Nature Genetics. 41: 1335-40. PMID 19915574 DOI: 10.1038/Ng.489  0.415
2009 Sauer CG, Kugathasan S. Pediatric inflammatory bowel disease: highlighting pediatric differences in IBD. Gastroenterology Clinics of North America. 38: 611-28. PMID 19913205 DOI: 10.1016/j.gtc.2009.07.010  0.379
2009 Scherr R, Essers J, Hakonarson H, Kugathasan S. Genetic determinants of pediatric inflammatory bowel disease: is age of onset genetically determined? Digestive Diseases (Basel, Switzerland). 27: 236-9. PMID 19786746 DOI: 10.1159/000228555  0.475
2009 Rosh JR, Lerer T, Markowitz J, Goli SR, Mamula P, Noe JD, Pfefferkorn MD, Kelleher KT, Griffiths AM, Kugathasan S, Keljo D, Oliva-Hemker M, Crandall W, Carvalho RS, Mack DR, et al. Retrospective Evaluation of the Safety and Effect of Adalimumab Therapy (RESEAT) in pediatric Crohn's disease. The American Journal of Gastroenterology. 104: 3042-9. PMID 19724267 DOI: 10.1038/Ajg.2009.493  0.385
2009 Crandall W, Hyams J, Kugathasan S, Griffiths A, Zrubek J, Olson A, Liu G, Heuschkel R, Markowitz J, Cohen S, Winter H, Veereman-Wauters G, Ferry G, Baldassano RN. Infliximab therapy in children with concurrent perianal Crohn disease: observations from REACH. Journal of Pediatric Gastroenterology and Nutrition. 49: 183-90. PMID 19561542 DOI: 10.1097/Mpg.0B013E3181A70F21  0.394
2009 Essers JB, Lee JJ, Kugathasan S, Stevens CR, Grand RJ, Daly MJ. Established genetic risk factors do not distinguish early and later onset Crohn's disease. Inflammatory Bowel Diseases. 15: 1508-14. PMID 19322901 DOI: 10.1002/Ibd.20922  0.416
2009 Wang K, Zhang H, Kugathasan S, Annese V, Bradfield JP, Russell RK, Sleiman PM, Imielinski M, Glessner J, Hou C, Wilson DC, Walters T, Kim C, Frackelton EC, Lionetti P, et al. Diverse genome-wide association studies associate the IL12/IL23 pathway with Crohn Disease. American Journal of Human Genetics. 84: 399-405. PMID 19249008 DOI: 10.1016/J.Ajhg.2009.01.026  0.355
2009 Turner D, Hyams J, Markowitz J, Lerer T, Mack DR, Evans J, Pfefferkorn M, Rosh J, Kay M, Crandall W, Keljo D, Otley AR, Kugathasan S, Carvalho R, Oliva-Hemker M, et al. Appraisal of the pediatric ulcerative colitis activity index (PUCAI). Inflammatory Bowel Diseases. 15: 1218-23. PMID 19161178 DOI: 10.1002/Ibd.20867  0.421
2009 Hyams JS, Lerer T, Griffiths A, Pfefferkorn M, Kugathasan S, Evans J, Otley A, Carvalho R, Mack D, Bousvaros A, Rosh J, Mamula P, Kay M, Crandall W, Oliva-Hemker M, et al. Long-term outcome of maintenance infliximab therapy in children with Crohn's disease. Inflammatory Bowel Diseases. 15: 816-22. PMID 19107783 DOI: 10.1002/Ibd.20845  0.423
2009 Markowitz J, Kugathasan S, Dubinsky M, Mei L, Crandall W, LeLeiko N, Oliva-Hemker M, Rosh J, Evans J, Mack D, Otley A, Pfefferkorn M, Bahar R, Vasiliauskas E, Wahbeh G, et al. Age of diagnosis influences serologic responses in children with Crohn's disease: a possible clue to etiology? Inflammatory Bowel Diseases. 15: 714-9. PMID 19107777 DOI: 10.1002/Ibd.20831  0.414
2009 Keljo DJ, Markowitz J, Langton C, Lerer T, Bousvaros A, Carvalho R, Crandall W, Evans J, Griffiths A, Kay M, Kugathasan S, LeLeiko N, Mack D, Mamula P, Moyer MS, et al. Course and treatment of perianal disease in children newly diagnosed with Crohn's disease. Inflammatory Bowel Diseases. 15: 383-7. PMID 19023863 DOI: 10.1002/Ibd.20767  0.474
2009 Rosh J, Lerer T, Markowitz J, Mamula P, Pfefferkorn M, Griffiths A, Kugathasan S, Keljo D, Oliva-Hemker M, Crandall W, Carvalho R, Mack D, Hyams J. Long Term Use of Adalimumab in Pediatric Crohnʼs Disease: A Multi-Center Study: 1458 The American Journal of Gastroenterology. 104. DOI: 10.14309/00000434-200910003-01458  0.352
2009 Schaefer M, Machan J, Kawatu D, Langton C, Markowitz J, Crandall W, Mack D, Evans J, Pfefferkorn M, Griffiths A, Otley A, Bousvaros A, Kugathasan S, Rosh J, Keljo D. Five-year incidence of surgery in a prospectively followed cohort of pediatric patients with Crohnʼs Disease: P-0069. Inflammatory Bowel Diseases. 15. DOI: 10.1097/00054725-200912002-00077  0.349
2009 Hyams J, Crandall W, Kugathasan S, Griffiths A, Blank M, Lang G, Heuschkel R, Veereman-Wauters G, Baldassano R. P192 - Disease duration does not affect outcome following infliximab therapy in children with Crohn's disease Journal of Crohn's and Colitis. 3. DOI: 10.1016/S1873-9946(09)60219-1  0.361
2009 Rosh JR, Mohamed A, Markowitz J, Mack DR, Griffiths AM, Bousvaros A, Kay MH, Mamula P, Pfefferkorn MD, Carvalho RS, Kugathasan S, Keljo DJ, Tomer G, LeLeiko NS, Oliva-Hemker M, et al. W1196 Utilization and Effect of Methotrexate in the Treatment of Pediatric Crohn's Disease: A Multi-Center Experience Gastroenterology. 136: A-675. DOI: 10.1016/S0016-5085(09)63109-7  0.335
2009 Lora M, Pfefferkorn MD, Langton CR, Markowitz J, Evans J, Rosh JR, Kay MH, Crandall W, Keljo DJ, Otley AR, Kugathasan S, Carvalho RS, Oliva-Hemker M, Bousvaros A, Leleiko NS, et al. W1189 Indeterminate Colitis (IC) in Children: A Two-Year Follow-Up Gastroenterology. 136: A-673-A-674. DOI: 10.1016/S0016-5085(09)63102-4  0.31
2009 Keljo DJ, Markowitz J, Langton CR, Lerer T, Bousvaros A, Carvalho RS, Crandall W, Evans J, Griffiths AM, Kay MH, Kugathasan S, LeLeiko NS, Mack DR, Oliva-Hemker M, Otley AR, et al. W1188 Growth in Pediatric Patients with IBD Treated with Infliximab or 6-Mercaptopurine/Azathioprine Gastroenterology. 136: A-673. DOI: 10.1016/S0016-5085(09)63101-2  0.311
2009 Hyams JS, Blank M, Johanns J, Crandall W, Kugathasan S, Griffiths AM, Heuschkel R, Markowitz J, Cohen SA, Winter HS, Veereman G, Ferry GD, Walters TD, Baldassano R. W1181 Long-Term Efficacy and Safety of Maintenance Infliximab for the Treatment of Moderate-to-Severe Pediatric Crohn's Disease: Results from the Reach Study Gastroenterology. 136: A-671-A-672. DOI: 10.1016/S0016-5085(09)63094-8  0.408
2009 Markowitz J, Mack DR, Leleiko NS, Otley AR, Evans JS, Pfefferkorn MD, Oliva-Hemker M, Crandall W, Rosh JR, Kappelman MD, Keljo DJ, Kugathasan S, Lerer T, Hyams JS. W1103 Anti-CBIR1 Is Commonly Detectable in Children with Ulcerative Colitis, But Does Not Predict Disease Course Over the First 2 Years of Treatment Gastroenterology. 136: A-654-A-655. DOI: 10.1016/S0016-5085(09)63017-1  0.384
2009 Siegel CA, Siegel LS, Hyams JS, Kugathasan S, Markowitz J, Rosh JR, Leleiko N, Mack DR, Crandall W, Evans J, Keljo DJ, Otley AR, Oliva-Hemker M, Langton CR, Wrobel IT, et al. 1108 A Prediction Tool to Help Children with Crohn's Disease and Their Parents Understand Individualized Risks of Disease Complications and Response to Therapy Gastroenterology. 136: A-172. DOI: 10.1016/S0016-5085(09)60775-7  0.412
2009 D'Mello S, Trauernicht A, Bonkowski EL, Willson T, Kugathasan S, Denson L. 73 Innate Dysfunction and Linear Growth Failure in Pediatric Crohn Disease Gastroenterology. 136: A-13. DOI: 10.1016/S0016-5085(09)60063-9  0.349
2008 Thayu M, Leonard MB, Hyams JS, Crandall WV, Kugathasan S, Otley AR, Olson A, Johanns J, Marano CW, Heuschkel RB, Veereman-Wauters G, Griffiths AM, Baldassano RN. Improvement in biomarkers of bone formation during infliximab therapy in pediatric Crohn's disease: results of the REACH study. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. 6: 1378-84. PMID 19081527 DOI: 10.1016/J.Cgh.2008.07.010  0.334
2008 Kugathasan S, Cohen S. Searching for new clues in inflammatory bowel disease: tell tales from pediatric IBD natural history studies. Gastroenterology. 135: 1038-41. PMID 18786536 DOI: 10.1053/J.Gastro.2008.08.030  0.453
2008 Kugathasan S, Baldassano RN, Bradfield JP, Sleiman PM, Imielinski M, Guthery SL, Cucchiara S, Kim CE, Frackelton EC, Annaiah K, Glessner JT, Santa E, Willson T, Eckert AW, Bonkowski E, et al. Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease. Nature Genetics. 40: 1211-5. PMID 18758464 DOI: 10.1038/Ng.203  0.454
2008 Peterson N, Guthery S, Denson L, Lee J, Saeed S, Prahalad S, Biank V, Ehlert R, Tomer G, Grand R, Rudolph C, Kugathasan S. Genetic variants in the autophagy pathway contribute to paediatric Crohn's disease. Gut. 57: 1336-7; author reply. PMID 18719149 DOI: 10.1136/Gut.2008.152207  0.43
2008 Dubinsky MC, Kugathasan S, Mei L, Picornell Y, Nebel J, Wrobel I, Quiros A, Silber G, Wahbeh G, Katzir L, Vasiliauskas E, Bahar R, Otley A, Mack D, Evans J, et al. Increased immune reactivity predicts aggressive complicating Crohn's disease in children. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. 6: 1105-11. PMID 18619921 DOI: 10.1016/J.Cgh.2008.04.032  0.405
2008 Punati J, Markowitz J, Lerer T, Hyams J, Kugathasan S, Griffiths A, Otley A, Rosh J, Pfefferkorn M, Mack D, Evans J, Bousvaros A, Moyer MS, Wyllie R, Oliva-Hemker M, et al. Effect of early immunomodulator use in moderate to severe pediatric Crohn disease. Inflammatory Bowel Diseases. 14: 949-54. PMID 18306311 DOI: 10.1002/Ibd.20412  0.401
2008 Walkiewicz D, Werlin SL, Fish D, Scanlon M, Hanaway P, Kugathasan S. Fecal calprotectin is useful in predicting disease relapse in pediatric inflammatory bowel disease. Inflammatory Bowel Diseases. 14: 669-73. PMID 18240279 DOI: 10.1002/ibd.20376  0.327
2008 Greifer M, Kugathasan S, Hyams J, Lerer T, Kohn N, Markowitz J. Effect of High Body Mass Index on the Course of Pediatric Crohnʼs Disease: 1363 The American Journal of Gastroenterology. 103. DOI: 10.14309/00000434-200809001-01363  0.325
2008 Hyams J, Crandall W, Kugathasan S, Griffiths A, Blank M, Lang G, Heuschkel R, Veereman-Wauters G, Baldassano R. Disease Duration Does Not Affect Outcome Following Infliximab in Children with Crohnʼs Disease: 1360 The American Journal of Gastroenterology. 103. DOI: 10.14309/00000434-200809001-01360  0.418
2008 Lee J, Escher J, Shuman M, Kugathasan S, Butler J, Lettre G, Hirschhorn J, Essers J, Sandler D, Forbes P, Grand R. Growth impairment in pediatric Inflammatory Bowel Disease: Role of parental heights and genetic variants: O-0017. Inflammatory Bowel Diseases. 14. DOI: 10.1097/00054725-200812003-00017  0.377
2008 Wang M, Kugathasan S, Cho J, Isaacs K, Lewis J, Valentine J, Gold M, Smoot D, Duerr R, Rioux J, Silverberg M, Harris M, Ford J, Kittles R, Brant S. African and European genetic admixture in African American IBD patients Inflammatory Bowel Diseases. 14: S8. DOI: 10.1097/00054725-200812001-00026  0.311
2008 Lee J, Escher J, Shuman M, Kugathasan S, Butler J, Lettre G, Hirschhorn J, Essers J, Sandier D, Forbes P, Grand R. Growth impairment in pediatric Inflammatory Bowel Disease Inflammatory Bowel Diseases. 14: S6. DOI: 10.1097/00054725-200812001-00017  0.314
2008 Otley AR, Markowitz J, LeLeiko NS, Griffiths AM, Crandall W, Kugathasan S, Oliva-Hemker M, Bousvaros A, Pfefferkorn MD, Mack DR, Evans J, Rosh JR, Keljo D, Mamula P, Moyer MS, et al. W1225 Budesonide Is An Effective But Underutilized Therapy in Pediatric Crohn Disease Gastroenterology. 134: A-659. DOI: 10.1016/S0016-5085(08)63076-0  0.41
2008 Rosh JR, Lerer T, Markowitz J, Goli SR, Mamula P, Noe JD, Pfefferkorn MD, Kelleher KT, Griffiths AM, Kugathasan S, Keljo D, Oliva-Hemker M, Crandall W, Carvalho RS, Mack DR, et al. W1219 Retrospective Evaluation of the Safety and Effect of Adalimumab Therapy (Reseat) in Pediatric Crohn's Disease Gastroenterology. 134: 18-18. DOI: 10.1016/S0016-5085(08)63070-X  0.375
2008 Dotson JL, Hyams JS, Markowitz J, LeLeiko NS, Mack DR, Evans J, Pfefferkorn MD, Griffiths AM, Otley AR, Bousvaros A, Kugathasan S, Rosh JR, Keljo D, Carvalho RS, Moyer MS, et al. W1128 Extra-Intestinal Manifestations of Pediatric Inflammatory Bowel Disease Gastroenterology. 134: A-639. DOI: 10.1016/S0016-5085(08)62982-0  0.458
2008 Bousvaros A, Lerer T, Markowitz J, Griffiths AM, Keljo D, LeLeiko NS, Mack DR, Evans J, Pfefferkorn MD, Otley AR, Kugathasan S, Rosh JR, Carvalho RS, Moyer MS, Kay MH, et al. W1127 Clinical Outcome Following Immunomodulator Therapy in Pediatric Ulcerative Colitis (UC): Results from a Prospective Multicenter Inception Cohort Gastroenterology. 134: A-639. DOI: 10.1016/S0016-5085(08)62981-9  0.31
2008 Schaefer ME, Hyams JS, Markowitz J, Mack DR, Griffiths AM, Otley AR, Bousvaros A, Keljo D, Evans J, Pfefferkorn MD, Kay MH, Mamula P, Rosh JR, Carvalho RS, Kugathasan S, et al. T1164 Surgery in a Prospectively Followed Cohort of Pediatric Patients with Crohn's Disease (CD) Gastroenterology. 134: A-498. DOI: 10.1016/S0016-5085(08)62323-9  0.404
2008 Peterson N, Guthery SL, Denson L, Lee JJ, Saeed S, Biank VF, Ehlert R, Tomer G, Grand RJ, Rudolph CD, Kugathasan S. M2053 Autophagy Like Genes (ATG16L1 & IRGM), IL23R and Three Other Variants Are Associated with Pediatric Onset Crohn's Disease (CD) with Similar Risks (Odds Ratio) to Adult Onset Gastroenterology. 134: A-459. DOI: 10.1016/S0016-5085(08)62146-0  0.428
2008 Hyams JS, Lerer T, Pfefferkorn MD, Kugathasan S, Evans J, Otley AR, Griffiths AM, Carvalho RS, Mack DR, Bousvaros A, Rosh JR, Mamula P, Moyer MS, Kay MH, Crandall W, et al. 924 Long-Term Outcome Following Infliximab Therapy in Pediatric Patients with Crohn Disease: Results from a Multicenter Study Gastroenterology. 134: A-134-A-135. DOI: 10.1016/S0016-5085(08)60624-1  0.36
2008 Saeed S, Kugathasan S. Epidemiology of pediatric inflammatory bowel disease Pediatric Inflammatory Bowel Disease. 45-60. DOI: 10.1007/978-0-387-73481-1_4  0.379
2008 Levine A, Kugathasan S, Annese V, Biank V, Leshinsky-Silver E, Davidovich O, Kimmel G, Shamir R, Palmieri O, Karban A, Broeckel U, Cucchiara S. Erratum: Pediatric onset Crohn's colitis is characterized by genotype-dependent age-related susceptibility (Inflamatory Bowel Diseases vol. 13 (1509-1515)) Inflammatory Bowel Diseases. 14. DOI: 10.1002/Ibd.20813  0.449
2007 Turner D, Grossman AB, Rosh J, Kugathasan S, Gilman AR, Baldassano R, Griffiths AM. Methotrexate following unsuccessful thiopurine therapy in pediatric Crohn's disease. The American Journal of Gastroenterology. 102: 2804-12; quiz 2803, . PMID 18042110 DOI: 10.1111/J.1572-0241.2007.01474.X  0.424
2007 Kugathasan S, Nebel J, Skelton JA, Markowitz J, Keljo D, Rosh J, LeLeiko N, Mack D, Griffiths A, Bousvaros A, Evans J, Mezoff A, Moyer S, Oliva-Hemker M, Otley A, et al. Body mass index in children with newly diagnosed inflammatory bowel disease: observations from two multicenter North American inception cohorts. The Journal of Pediatrics. 151: 523-7. PMID 17961699 DOI: 10.1016/J.Jpeds.2007.04.004  0.405
2007 Levine A, Kugathasan S, Annese V, Biank V, Leshinsky-Silver E, Davidovich O, Kimmel G, Shamir R, Palmieri O, Orazio P, Karban A, Broeckel U, Cucchiara S. Pediatric onset Crohn's colitis is characterized by genotype-dependent age-related susceptibility. Inflammatory Bowel Diseases. 13: 1509-15. PMID 17763471 DOI: 10.1002/Ibd.20244  0.444
2007 Kugathasan S, Saubermann LJ, Smith L, Kou D, Itoh J, Binion DG, Levine AD, Blumberg RS, Fiocchi C. Mucosal T-cell immunoregulation varies in early and late inflammatory bowel disease. Gut. 56: 1696-705. PMID 17682002 DOI: 10.1136/Gut.2006.116467  0.467
2007 Kugathasan S, Fiocchi C. Progress in basic inflammatory bowel disease research. Seminars in Pediatric Surgery. 16: 146-53. PMID 17602969 DOI: 10.1053/J.Sempedsurg.2007.04.002  0.422
2007 Biank V, Broeckel U, Kugathasan S. Pediatric inflammatory bowel disease: clinical and molecular genetics. Inflammatory Bowel Diseases. 13: 1430-8. PMID 17600381 DOI: 10.1002/Ibd.20213  0.481
2007 Mack DR, Langton C, Markowitz J, LeLeiko N, Griffiths A, Bousvaros A, Evans J, Kugathasan S, Otley A, Pfefferkorn M, Rosh J, Mezoff A, Moyer S, Oliva-Hemker M, Rothbaum R, et al. Laboratory values for children with newly diagnosed inflammatory bowel disease. Pediatrics. 119: 1113-9. PMID 17545378 DOI: 10.1542/Peds.2006-1865  0.479
2007 Tao GZ, Strnad P, Zhou Q, Kamal A, Zhang L, Madani ND, Kugathasan S, Brant SR, Cho JH, Omary MB, Duerr RH. Analysis of keratin polypeptides 8 and 19 variants in inflammatory bowel disease. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. 5: 857-64. PMID 17509943 DOI: 10.1016/J.Cgh.2007.02.017  0.415
2007 Bousvaros A, Antonioli DA, Colletti RB, Dubinsky MC, Glickman JN, Gold BD, Griffiths AM, Jevon GP, Higuchi LM, Hyams JS, Kirschner BS, Kugathasan S, Baldassano RN, et al. Differentiating ulcerative colitis from Crohn disease in children and young adults: report of a working group of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition and the Crohn's and Colitis Foundation of America. Journal of Pediatric Gastroenterology and Nutrition. 44: 653-74. PMID 17460505 DOI: 10.1097/Mpg.0B013E31805563F3  0.47
2007 Hyams J, Crandall W, Kugathasan S, Griffiths A, Olson A, Johanns J, Liu G, Travers S, Heuschkel R, Markowitz J, Cohen S, Winter H, Veereman-Wauters G, Ferry G, Baldassano R, et al. Induction and maintenance infliximab therapy for the treatment of moderate-to-severe Crohn's disease in children. Gastroenterology. 132: 863-73; quiz 1165-6. PMID 17324398 DOI: 10.1053/J.Gastro.2006.12.003  0.341
2007 Kappelman MD, Bousvaros A, Hyams J, Markowitz J, Pfefferkorn M, Kugathasan S, Rosh J, Otley A, Mack D, Griffiths A, Evans J, Grand R, Langton C, Kleinman K, Finkelstein JA. Intercenter variation in initial management of children with Crohn's disease. Inflammatory Bowel Diseases. 13: 890-5. PMID 17286275 DOI: 10.1002/Ibd.20121  0.403
2007 Hyams JS, Wilson DC, Thomas A, Heuschkel R, Mitton S, Mitchell B, Daniels R, Libonati MA, Zanker S, Kugathasan S. Natalizumab therapy for moderate to severe Crohn disease in adolescents. Journal of Pediatric Gastroenterology and Nutrition. 44: 185-91. PMID 17255829 DOI: 10.1097/01.Mpg.0000252191.05170.E7  0.344
2007 Biank V, Friedrichs F, Babusukumar U, Wang T, Stoll M, Broeckel U, Kugathasan S. DLG5 R30Q variant is a female-specific protective factor in pediatric onset Crohn's disease. The American Journal of Gastroenterology. 102: 391-8. PMID 17156146 DOI: 10.1111/J.1572-0241.2006.01011.X  0.408
2007 Otley A, Hyams J, Baldassano R, Crandall W, Kugathasan S, Xu S, Yan S, Heuschkel R, Griffiths A. The effects of Infliximab therapy on health-related quality of life in pediatric crohnʼs disease: P-0071 Inflammatory Bowel Diseases. 13: 669-670. DOI: 10.1097/00054725-200705001-00091  0.3
2007 Stephens MC, Kugathasan S. Chapter 98 – Inflammatory Bowel Disease Comprehensive Pediatric Hospital Medicine. 628-632. DOI: 10.1016/B978-032303004-5.50102-2  0.449
2006 Biank VF, Kugathasan S. What are the risk factors for surgery and their implications for management of children with Crohn's disease? Nature Clinical Practice. Gastroenterology & Hepatology. 3: 660-1. PMID 17130872 DOI: 10.1038/Ncpgasthep0658  0.37
2006 Bousvaros A, Sylvester F, Kugathasan S, Szigethy E, Fiocchi C, Colletti R, Otley A, Amre D, Ferry G, Czinn SJ, Splawski JB, Oliva-Hemker M, Hyams JS, Faubion WA, Kirschner BS, et al. Challenges in pediatric inflammatory bowel disease. Inflammatory Bowel Diseases. 12: 885-913. PMID 16954808 DOI: 10.1097/01.Mib.0000228358.25364.8B  0.419
2006 Otley AR, Griffiths AM, Hale S, Kugathasan S, Pfefferkorn M, Mezoff A, Rosh J, Tolia V, Markowitz J, Mack D, Oliva-Hemker M, Wyllie R, Rothbaum R, Bousvaros A, Del Rosario JF, et al. Health-related quality of life in the first year after a diagnosis of pediatric inflammatory bowel disease. Inflammatory Bowel Diseases. 12: 684-91. PMID 16917222 DOI: 10.1097/00054725-200608000-00003  0.42
2006 Kugathasan S, Amre D. Inflammatory bowel disease--environmental modification and genetic determinants. Pediatric Clinics of North America. 53: 727-49. PMID 16873002 DOI: 10.1016/J.Pcl.2006.05.009  0.43
2006 Markowitz J, Hyams J, Mack D, Leleiko N, Evans J, Kugathasan S, Pfefferkorn M, Mezoff A, Rosh J, Tolia V, Otley A, Griffiths A, Moyer MS, Oliva-Hemker M, Wyllie R, et al. Corticosteroid therapy in the age of infliximab: acute and 1-year outcomes in newly diagnosed children with Crohn's disease. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. 4: 1124-9. PMID 16861053 DOI: 10.1016/J.Cgh.2006.05.011  0.348
2006 Babusukumar U, Wang T, McGuire E, Broeckel U, Kugathasan S. Contribution of OCTN variants within the IBD5 locus to pediatric onset Crohn's disease. The American Journal of Gastroenterology. 101: 1354-61. PMID 16771961 DOI: 10.1111/J.1572-0241.2006.00564.X  0.401
2006 Friedrichs F, Brescianini S, Annese V, Latiano A, Berger K, Kugathasan S, Broeckel U, Nikolaus S, Daly MJ, Schreiber S, Rioux JD, Stoll M. Evidence of transmission ratio distortion of DLG5 R30Q variant in general and implication of an association with Crohn disease in men. Human Genetics. 119: 305-11. PMID 16446977 DOI: 10.1007/S00439-006-0133-1  0.383
2006 Binion DG, Kugathasan S, Dwinell MB. Molecular stratification of Crohn's disease by chemokine receptors: fractalkine receptor polymorphisms define a fibrostenosing ileal subgroup. The American Journal of Gastroenterology. 101: 107-9. PMID 16405541 DOI: 10.1111/J.1572-0241.2006.00357.X  0.454
2006 Biank VF, Friedrichs F, Babusukumar U, Wang T, Stoll M, Broeckel U, Kugathasan S. DLG5 R30Q VARIANT AND GENDER INTERACTIONS IN PEDIATRIC-ONSET CROHN'S DISEASE (CD) Journal of Pediatric Gastroenterology and Nutrition. 43: E74. DOI: 10.1097/00005176-200610000-00221  0.447
2006 Keljo D, Markowitz J, Langton C, Lerer T, Kugathasan S, Griffiths A, Otley A, Rosh J, Pfefferkorn M, Mack D, Evans J, Bousvaros A, Moyer S, Rothbaum R, Wyllie R, et al. PERIANAL FISTULAE IN PEDIATRIC CROHN DISEASE Journal of Pediatric Gastroenterology and Nutrition. 43: E51. DOI: 10.1097/00005176-200610000-00148  0.483
2006 Mikhailov T, Furner S, Kugathasan S. ENVIRONMENTAL (LACK OF BREASTFEEDING) AND GENETIC (NOD2/CARD15) RISK FACTORS IN PEDIATRIC ONSET CROHN'S DISEASE (CD) Journal of Pediatric Gastroenterology and Nutrition. 43: E49. DOI: 10.1097/00005176-200610000-00141  0.442
2006 Garrity A, Lerer T, Otley A, Markowitz J, Griffiths A, Mack D, Evans J, Bousvaros A, Pfefferkorn M, Rothbaum R, Joel R, delRosario F, Kugathasan S, Wyllie R, Mezoff A, et al. DOES HAVING A FAMILY HISTORY OF INFLAMMATORY BOWEL DISEASE AFFECT QUALITY OF LIFE IN NEWLY DIAGNOSED CHILDREN? Journal of Pediatric Gastroenterology and Nutrition. 43: E48. DOI: 10.1097/00005176-200610000-00137  0.371
2006 Hyams J, Markowitz J, Lerer T, Kugathasan S, Rosh J, Bousvaros A, Evans J, Mack D, Otley A, Griffiths A, Wyllie R, Mezoff A, Oliva-Hemker M, Pfefferkorn M. PATTERNS OF INFLIXIMAB USE IN CHILDREN WITH CROHN DISEASE Journal of Pediatric Gastroenterology and Nutrition. 43: E46. DOI: 10.1097/00005176-200610000-00131  0.388
2005 Hyams J, Markowitz J, Otley A, Rosh J, Mack D, Bousvaros A, Kugathasan S, Pfefferkorn M, Tolia V, Evans J, Treem W, Wyllie R, Rothbaum R, del Rosario J, Katz A, et al. Evaluation of the pediatric crohn disease activity index: a prospective multicenter experience. Journal of Pediatric Gastroenterology and Nutrition. 41: 416-21. PMID 16205508 DOI: 10.1097/01.Mpg.0000183350.46795.42  0.449
2005 Bousvaros A, Guandalini S, Baldassano RN, Botelho C, Evans J, Ferry GD, Goldin B, Hartigan L, Kugathasan S, Levy J, Murray KF, Oliva-Hemker M, Rosh JR, Tolia V, Zholudev A, et al. A randomized, double-blind trial of Lactobacillus GG versus placebo in addition to standard maintenance therapy for children with Crohn's disease. Inflammatory Bowel Diseases. 11: 833-9. PMID 16116318 DOI: 10.1097/01.Mib.0000175905.00212.2C  0.363
2005 Galbraith SS, Drolet BA, Kugathasan S, Paller AS, Esterly NB. Asymptomatic inflammatory bowel disease presenting with mucocutaneous findings. Pediatrics. 116: e439-44. PMID 16099852 DOI: 10.1542/Peds.2004-2281  0.41
2005 Kugathasan S, Loizides A, Babusukumar U, McGuire E, Wang T, Hooper P, Nebel J, Kofman G, Noel R, Broeckel U, Tolia V. Comparative phenotypic and CARD15 mutational analysis among African American, Hispanic, and White children with Crohn's disease. Inflammatory Bowel Diseases. 11: 631-8. PMID 15973116 DOI: 10.1097/01.Mib.0000171279.05471.21  0.39
2005 Walkiewicz D, Werlin SL, Scanlon MC, Mao JN, Hanaway PJ, Kugathasan S, Fish D. Fecal Calprotectin Level Predicts Clinical Relapse in Clinically Quiescent Crohnʼs Disease: 1043 The American Journal of Gastroenterology. 100. DOI: 10.14309/00000434-200509001-01043  0.328
2005 Kugathasan S, Babusukumar U, Wang T, McGuire E, Broeckel U. DLG5-113A MUTATION IS STRONGLY ASSOCIATED WITH MALE GENDER BUT PROTECTIVE IN FEMALES IN PEDIATRIC ONSET CROHN??S DISEASE (CD) Journal of Pediatric Gastroenterology and Nutrition. 41: 549. DOI: 10.1097/01.Mpg.0000182038.73751.70  0.368
2005 Walkiewicz D, Werlin S, Fish D, Hanaway P, Kugathasan S, Salzman N. FECAL CALPROTECTIN DIFFERENTIATES BETWEEN CHILDREN WITH ACTIVE INFLAMMATORY BOWEL DISEASE (IBD) AND HEALTHY CHILDREN Journal of Pediatric Gastroenterology and Nutrition. 41: 548. DOI: 10.1097/01.Mpg.0000182035.50880.Ab  0.393
2005 Utterson E, Boslaugh S, Rothbaum R, Hyams J, Markowitz J, Griffiths A, Moyer S, Rosh J, Mack D, Evans J, Kugathasan S, Pfefferkorn M, Mezoff A, Tolia V, Otley A, et al. RESOURCE UTILIZATION FOR CHILDREN WITH NEWLY DIAGNOSED INFLAMMATORY BOWEL DISEASE Journal of Pediatric Gastroenterology and Nutrition. 41: 548. DOI: 10.1097/01.Mpg.0000182034.50880.E2  0.435
2005 Michail S, Hyams J, Mezoff A, Otley A, Rosh J, Mack D, Bousvaros A, Kugathasan S, Pfefferkorn M, Tolia V, Evans J, Wyllie R, Rothbaum R, Rosario Jd, Olivia-Hemker M, et al. INFLAMMATORY BOWEL DISEASE SEROLOGIC MARKERS IN CHILDREN; CORRELATION WITH CLINICAL FINDINGS: A REPORT BY THE PEDIATRIC IBD COLLABORATIVE GROUP Journal of Pediatric Gastroenterology and Nutrition. 41: 546. DOI: 10.1097/01.Mpg.0000182029.76429.08  0.44
2005 Babusukumar U, Tolia V, Loizides A, Wang T, McGuire E, Kofman G, Rajasingham R, Broeckel U, Kugathasan S. CARD15 & IBD5 DO NOT CONTRIBUTE TO CROHN??S DISEASE (CD) SUSCEPTIBILITY IN AFRICAN-AMERICAN & HISPANIC CHILDREN; A MULTI-CENTER STUDY Journal of Pediatric Gastroenterology and Nutrition. 41: 546. DOI: 10.1097/01.Mpg.0000182028.68806.A7  0.46
2005 Kugathasan S, Babusukumar U, McGuire E, Wang T, Nebel J, Broeckel U. IBD5 IS STRONGLY ASSOCIATED WITH PEDIATRIC ONSET CROHN??S DISEASE (CD): CONFIRMATION BY FAMILY-BASED ASSOCIATION & CASE CONTROL ANALYSIS FROM A PROSPECTIVE POPULATION-BASED NORTH AMERICAN COHORT Journal of Pediatric Gastroenterology and Nutrition. 41: 545-546. DOI: 10.1097/01.Mpg.0000182027.68806.43  0.436
2005 Hyams J, Crandall W, Kugathasan S, Heuschkel R, Griffiths A, Cohen S, Markowitz J, Olson A, Johanns J, Baldassano R. A RANDOMIZED, MULTICENTER, OPEN-LABEL STUDY TO EVALUATE THE SAFETY AND EFFICACY OF INFLIXIMAB IN PEDIATRIC PATIENTS WITH MODERATE-TO-SEVERE CROHN??S DISEASE Journal of Pediatric Gastroenterology and Nutrition. 41: 539. DOI: 10.1097/01.Mpg.0000182004.06031.Ce  0.351
2005 Grundy J, Pan W, Kugathasan S, Nagpala F, Hilton D, Taylor J, Goldblum R, Libonati M, Daniels R, Giacchino J. PHARMACOKINETICS AND PHARMACODYNAMICS OF NATALIZUMAB IN A PHASE 2 STUDY OF ADOLESCENT PATIENTS WITH CROHN??S DISEASE Journal of Pediatric Gastroenterology and Nutrition. 41: 538. DOI: 10.1097/01.Mpg.0000182003.06031.00  0.352
2004 Kugathasan S, Collins N, Maresso K, Hoffmann RG, Stephens M, Werlin SL, Rudolph C, Broeckel U. CARD15 gene mutations and risk for early surgery in pediatric-onset Crohn's disease. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. 2: 1003-9. PMID 15551253 DOI: 10.1016/S1542-3565(04)00452-5  0.407
2004 Sands BE, Cuffari C, Katz J, Kugathasan S, Onken J, Vitek C, Orenstein W. Guidelines for immunizations in patients with inflammatory bowel disease. Inflammatory Bowel Diseases. 10: 677-92. PMID 15472534 DOI: 10.1097/00054725-200409000-00028  0.357
2004 Fish D, Kugathasan S. Inflammatory bowel disease. Adolescent Medicine Clinics. 15: 67-90, ix. PMID 15272257 DOI: 10.1016/S1547336803000135  0.393
2004 Markowitz J, Hyams J, Mack D, Otley A, Rosh J, Pfefferkorn M, Tolia V, Oliva-Hemker M, Mezoff A, Treem W, Moyer S, Kugathasan S. Nod2 Variants In Children With Crohn Disease Are Associated With Onset Of Disease In The First Decade Of Life: 784 The American Journal of Gastroenterology. 99. DOI: 10.14309/00000434-200410001-00780  0.456
2004 Hyams J, Griffiths A, Markowitz J, Otley A, Mack D, Kugathasan S, Rosh J, Bousvaros A, Evans J, Rothbaum R, Wyllie R, Treem W, Katz A, Tolia V, Oliva-Hemker M, et al. P0712 RE-EVALUATION OF THE PEDIATRIC CROHN???S DISEASE ACTIVITY INDEX: USEFULNESS IN THE PRACTICE SETTING Journal of Pediatric Gastroenterology and Nutrition. 39: S328. DOI: 10.1097/00005176-200406001-00836  0.37
2004 Pfefferkorn M, Hyams J, Markowitz J, Griffiths A, Daggy J, Bousvaros A, Del Rosario F, Evans J, Grand R, Katz A, Kugathasan S, Mack D, Mezoff A, Oliva-Hemker M, Otley A, et al. P0687 CHARACTERIZATION OF HEIGHT AND WEIGHT PATTERNS IN NEWLY DIAGNOSED CHILDREN WITH INFLAMMATORY BOWEL DISEASE (IBD) Journal of Pediatric Gastroenterology and Nutrition. 39: S318. DOI: 10.1097/00005176-200406001-00811  0.409
2004 Mack D, Hyams J, Markowitz J, Griffiths A, Bousvaros A, Del Rosario J, Evans J, Grand R, Katz A, Kugathasan S, Mezoff A, Oliva-Hemker M, Otley A, Pfefferkorn M, Rosh J, et al. P0666 LAB PARAMETERS IN CHILDREN WITH INFLAMMATORY BOWEL DISEASE (IBD) AT DIAGNOSIS Journal of Pediatric Gastroenterology and Nutrition. 39: S310. DOI: 10.1097/00005176-200406001-00790  0.423
2004 Markowitz J, Rosh J, Hyams J, Bousvaros A, Del Rosario J, Evans J, Grand R, Griffiths A, Katz A, Kugathasan S, Mack D, Mezoff A, Oliva-Hemker M, Otley A, Pfefferkorn M, et al. P0615 STEROID THERAPY IN THE AGE OF INFLIXIMAB (IFX): IMMEDIATE AND 1 YEAR OUTCOME IN NEWLY DIAGNOSED CHILDREN WITH CROHN DISEASE (CD) Journal of Pediatric Gastroenterology and Nutrition. 39: S291. DOI: 10.1097/00005176-200406001-00739  0.394
2004 Kugathasan S, Maresso K, Collins N, Broeckel U. P0135 PP LEU 1007FSINSC IS STRONGLY ASSOCIATED WITH EARLY ONSET AND STRICTURING CROHN???S DISEASE IN CHILDREN Journal of Pediatric Gastroenterology and Nutrition. 39: S109. DOI: 10.1097/00005176-200406001-00259  0.423
2004 Hyams J, Wilson D, Thomas A, Mitchell B, Kugathasan S. O0107 A PHASE II, MULTICENTER, OPEN-LABEL STUDY OF THE SAFETY, TOLERABILITY, AND EFFECTIVENESS OF NATALIZUMAB IN ADOLESCENTS WITH MODERATELY TO SEVERELY ACTIVE CROHN???S DISEASE. Journal of Pediatric Gastroenterology and Nutrition. 39: S49. DOI: 10.1097/00005176-200406001-00109  0.303
2003 Werlin SL, Kugathasan S, Frautschy BC. Pancreatitis in children. Journal of Pediatric Gastroenterology and Nutrition. 37: 591-5. PMID 14581803 DOI: 10.1097/00005176-200311000-00017  0.32
2003 Kugathasan S, Judd RH, Hoffmann RG, Heikenen J, Telega G, Khan F, Weisdorf-Schindele S, San Pablo W, Perrault J, Park R, Yaffe M, Brown C, Rivera-Bennett MT, Halabi I, Martinez A, et al. Epidemiologic and clinical characteristics of children with newly diagnosed inflammatory bowel disease in Wisconsin: a statewide population-based study. The Journal of Pediatrics. 143: 525-31. PMID 14571234 DOI: 10.1067/S0022-3476(03)00444-X  0.466
2003 Kugathasan S, Miranda A, Nocton J, Drolet BA, Raasch C, Binion DG. Dermatologic manifestations of Crohn disease in children: response to infliximab. Journal of Pediatric Gastroenterology and Nutrition. 37: 150-4. PMID 12883301 DOI: 10.1097/00005176-200308000-00013  0.335
2003 Attila T, Shaker K, Kounev V, Levy MB, Knox JF, Emmons J, Prajapati D, Kugathasan S, Binion DG. Episodic infusion schedule and azathioprine (Aza) intolerance correlate with the development of severe adverse reaction during infliximab (Inflix) retreatment for Crohn's disease (Cd) Gastroenterology. 124: A526. DOI: 10.1016/S0016-5085(03)82664-1  0.401
2003 Markowitz J, Hyams J, Griffiths A, Bousvaros A, Fernando Del Rosario J, Evans J, Grand R, Katz A, Kugathasan S, Mack D, Mezoff A, Oliva-Hemker M, Otley A, Pfefferkorn M, Rosh J, et al. Initial response to treatment (Rx) and need for intensified (step-up) therapy in children with newly diagnosed, inflammatory bowel disease (IBD): A preliminary investigation by the pediatric IBD collaborative research group Gastroenterology. 124: A518. DOI: 10.1016/S0016-5085(03)82620-3  0.442
2003 Kugathasan S, Collins N, Maresso K, Matter A, Sherry K, Rudolph C, Binion D, Broeckel U. Nod2/card15 mutations and phenotypic correlation in pediatric Crohn's disease (Cd) Gastroenterology. 124: A375-A376. DOI: 10.1016/S0016-5085(03)81900-5  0.421
2003 Johnson NA, Dwinell M, Tolia V, Binion D, Kugathasan S. Expression of CXCR3, CXCR4, CCR5 in early and late pediatric Crohn's disease intestinal mucosal T-lymphocytes Gastroenterology. 124: A323. DOI: 10.1016/S0016-5085(03)81626-8  0.403
2003 Kugathasan S, Cheng K, Johnson NA, Ogawa H, Rafiee P, Binion DG, Thiagalingam S. Inactivation of mucosal SMAD signaling is associated with the progression from early to late Crohn's disease (Cd) Gastroenterology. 124: A313. DOI: 10.1016/S0016-5085(03)81579-2  0.436
2003 Otley A, Griffiths A, Hyams J, Markowitz J, J AB, Del Rosario F, Evans J, Grand R, Katz A, Kugathasan S, Mack D, Mezoff A, Oliva-Hemker M, Pfefferkom M, Rosh J, et al. IMPACT-II QOL questionnaire: Performance in new-onset pediatric IBD patients (the pediatric IBD collaborative registry) Gastroenterology. 124: A218-A219. DOI: 10.1016/S0016-5085(03)81098-3  0.321
2003 Kugathasan S, Heikenen J, Judd R, Brown C, Binion D. Defining the natural history of Crohn's disease behavior prospectively: Categorization of newly diagnosed pediatric patients using Vienna classification Gastroenterology. 124: A217. DOI: 10.1016/S0016-5085(03)81088-0  0.403
2003 Fish D, Werlin S, Rudolph C, Martinez A, Halabi I, Telega G, Blank E, Khan F, Raasch C, Brown C, Judd R, Heikenen J, Kugathasan S. A population based prospective study of clinical patterns, natural history and progression of pediatric ulcerative colitis (UC) in wisconsin (Wi) Gastroenterology. 124: A214. DOI: 10.1016/S0016-5085(03)81076-4  0.321
2003 Kounev V, Levy MB, Attila T, Saeian K, Kugathasan S, Knox JF, Emmons J, Hogan WJ, Shaker R, Binion DG. Increased rates of drug allergy in inflammatory bowel disease (IBD) patients compared to irritable bowel syndrome (IBS) patients and normal controls Gastroenterology. 124: A214. DOI: 10.1016/S0016-5085(03)81073-9  0.357
2003 Attila T, Saeian K, Knox JF, Emmons J, Calabrese L, Rose D, Prajapati D, Kugathasan S, Otterson MF, Binion DG. Correlation of short inflammatory bowel disease questionnaire (Sibdq) with clinical status in routine management of Crohn's disease (Cd) patients including ostomates Gastroenterology. 124: A199-A200. DOI: 10.1016/S0016-5085(03)81000-4  0.487
2001 Kugathasan S. Pediatric inflammatory bowel disease: clinical and therapeutic aspects. Current Opinion in Gastroenterology. 17: 350-5. PMID 17031182 DOI: 10.1097/00001574-200107000-00009  0.357
2001 Kugathasan S. Prolonged duration of response to infliximab in early pediatric Crohn's disease Journal of Pediatric Gastroenterology and Nutrition. 33: S40-S43. PMID 11685975 DOI: 10.1097/00005176-200109001-00007  0.442
2001 Puchner TC, Kugathasan S, Kelly KJ, Binion DG. Successful desensitization and therapeutic use of infliximab in adult and pediatric Crohn's disease patients with prior anaphylactic reaction. Inflammatory Bowel Diseases. 7: 34-7. PMID 11233658 DOI: 10.1097/00054725-200102000-00005  0.394
2001 Kugathasan S, Judd RH, Khan FN, Gourley GR, Heikenen JB, Werlin SL, Brown CW, Martinez A, Blank EL, Perreault JF, Yaffe MR, Park R, Rivera M, Telega G, Halibi I, et al. Wisconsin statewide survey of pediatric IBD diagnosis in the year 2000: Changing patterns of Crohn's disease (CD) and ulcerative colitis (UC) Gastroenterology. 120: A460. DOI: 10.1016/S0016-5085(08)82279-2  0.454
2001 Kugathasan S, Vasilopoulos S, Emmons JE, Raasch C, Kim JP, Werlin SL, Martinez A, Blank EL, Levy MB, Kelly KJ, Binion DG. Allergic reactions to infliximab retreatment are decreased in pediatric Crohn's disease (CD) patients compared to adults Gastroenterology. 120: A69. DOI: 10.1016/S0016-5085(08)80342-3  0.421
2000 Kugathasan S, Werlin SL, Martinez A, Rivera MT, Heikenen JB, Binion DG. Prolonged duration of response to infliximab in early but not late pediatric Crohn's disease American Journal of Gastroenterology. 95: 3189-3194. PMID 11095340 DOI: 10.1016/S0002-9270(00)02056-6  0.479
2000 Kugathasan S, Werlin SL, Aktay N, Martinez A, Heikenen JB, Binion DG. Prolonged duration of response to Inflixlmab in early pediatric Crohn's disease (CD): One year followup Gastroenterology. 118: A566-A567. DOI: 10.1016/S0016-5085(00)84401-7  0.44
2000 Kugathasan S, Stein DJ, Truitt RL, Binion DG. Distinct mucosal T cell phenotypes in early and late pediatric Crohn's disease (CD): Increased naive T cells are found in late, but not early CD Gastroenterology. 118: A347. DOI: 10.1016/S0016-5085(00)83488-5  0.365
2000 Vasilopoulos S, Kugathasan S, Saeian K, Emmons JE, Hogan WJ, Otterson MF, Telford GL, Binion DG. Intestinal strictures complicating initially successful infliximab treatment for luminal Crohn's disease The American Journal of Gastroenterology. 95: 2503-2503. DOI: 10.1016/S0002-9270(00)01467-2  0.417
1998 Kugathasan S, Itoh J, Boyle JT, Levine AD, Fiocchi C. DISTINCT MUCOSAL T-CELL RESPONSES TO IL-12 IN EARLY AND LATE STAGES OF INFLAMMATORY BOWEL DISEASE (IBD) Journal of Pediatric Gastroenterology & Nutrition. 27: 471. DOI: 10.1097/00005176-199810000-00054  0.356
1998 Kugathasan S, Itoh J, Kou D, Boyle J, Levine A, Fiocchi C. IL-12 receptor β2 chain upregulation in mucosal tcells in early but not late Crohn's disease (CD): implications for variable IFN-γ production during disease progression Gastroenterology. 114: A1015. DOI: 10.1016/S0016-5085(98)84130-9  0.378
1998 Itoh J, Kugathasan S, McCormick T, Lapetina E, Levine A, Fiocchi C. Resistance of Crohn's disease (CD) mucosal T-cells to cell death is independent of trigger: Decreased anti-Fas and nitric oxide (NO)-induced apoptosis Gastroenterology. 114: A381. DOI: 10.1016/S0016-5085(98)81543-6  0.33
1997 Kugathasan S, Boyle JT, Dahms BB, O'Riordan MA, Fiocchi C. MUCOSAL T-CELL REACTIVITY IN CHILDREN WITH INTESTINAL INFLAMMATION PREDICTS DIAGNOSIS OF CROHN'S DISEASE (CD) AND ULCERATIVE COLITIS (UC) Journal of Pediatric Gastroenterology &Amp Nutrition. 25: 452. DOI: 10.1097/00005176-199710000-00059  0.447
1996 Kugathasan S, Binion DG, Boyle JT, Fiocchi C. 85 DIFFERENTIAL GROWTH AND CLONALITY OF GUT T-CELLS AMONG CROHN'S DISEASE (CD), ULCERATIVE COLITIS (UC), UNDETERMINED INFLAMMATION (NON-IBD) AND CONTROL CHILDREN Journal of Pediatric Gastroenterology &Amp Nutrition. 23: 363. DOI: 10.1097/00005176-199610000-00115  0.444
Show low-probability matches.