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M. Eugenio Vazquez - Publications

Affiliations: 
2001-2004 Chemistry Massachusetts Institute of Technology, Cambridge, MA, United States 
 2004-2011 Organic Chemistry universidade de santiago de compostela, Santiago de Compostela, Galicia, Spain 
 2011- CIQUS universidade de santiago de compostela, Santiago de Compostela, Galicia, Spain 
Area:
Chemistry, Chemical Biology
Website:
http://www.usc.es/chembiousc
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63 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Alcalde-Ordóñez A, Barreiro-Piñeiro N, McGorman B, Gómez-González J, Bouzada D, Rivadulla F, Vázquez ME, Kellett A, Martínez-Costas J, López MV. A copper(ii) peptide helicate selectively cleaves DNA replication foci in mammalian cells. Chemical Science. 14: 14082-14091. PMID 38098723 DOI: 10.1039/d3sc03303a  0.455
2022 Learte-Aymamí S, Martin-Malpartida P, Roldán-Martín L, Sciortino G, Couceiro JR, Maréchal JD, Macias MJ, Mascareñas JL, Vázquez ME. Controlling oncogenic KRAS signaling pathways with a Palladium-responsive peptide. Communications Chemistry. 5: 75. PMID 36697641 DOI: 10.1038/s42004-022-00691-7  0.685
2022 Gómez-González J, Martínez-Castro L, Tolosa-Barrilero J, Alcalde-Ordóñez A, Learte-Aymamí S, Mascareñas JL, García-Martínez JC, Martínez-Costas J, Maréchal JD, Vázquez López M, Vázquez ME. Selective recognition of A/T-rich DNA 3-way junctions with a three-fold symmetric tripeptide. Chemical Communications (Cambridge, England). PMID 35730795 DOI: 10.1039/d2cc02874c  0.757
2021 Gómez-González J, Bouzada D, Pérez-Márquez LA, Sciortino G, Maréchal JD, Vázquez López M, Vázquez ME. Stereoselective Self-Assembly of DNA Binding Helicates Directed by the Viral β-Annulus Trimeric Peptide Motif. Bioconjugate Chemistry. PMID 34320309 DOI: 10.1021/acs.bioconjchem.1c00312  0.422
2020 Gómez-González J, Pérez Y, Sciortino G, Roldan-Martín L, Martínez-Costas J, Maréchal JD, Alfonso I, Vázquez M, Vazquez ME. Dynamic Stereoselection of Peptide Helicates and Their Selective Labeling of DNA Replication Foci in Cells. Angewandte Chemie (International Ed. in English). PMID 33290612 DOI: 10.1002/anie.202013039  0.43
2020 Rodriguez J, Mosquera J, Learte-Aymamı S, Vázquez ME, Mascareñas JL. Stimuli-Responsive DNA Binding by Synthetic Systems. Accounts of Chemical Research. PMID 32997936 DOI: 10.1021/acs.accounts.0c00415  0.846
2020 Learte-Aymamí S, Rodríguez J, Vazquez ME, Mascareñas JL. Assembly of a ternary metallopeptide complex at specific DNA sites mediated by an AT-Hook adaptor. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 32237247 DOI: 10.1002/Chem.202001277  0.822
2020 Sánchez MI, Vida Y, Pérez-Inestrosa E, Mascareñas JL, Vázquez ME, Sugiura A, Martínez-Costas J. MitoBlue as a tool to analyze the mitochondria-lysosome communication. Scientific Reports. 10: 3528. PMID 32103132 DOI: 10.1038/S41598-020-60573-7  0.755
2020 Carreira-Barral I, Riopedre-Fernández M, de Blas A, Mosquera J, Vázquez ME, Platas-Iglesias C, Esteban-Gómez D. Ditopic binuclear copper(II) complexes for DNA cleavage. Journal of Inorganic Biochemistry. 205: 110995. PMID 31955057 DOI: 10.1016/j.jinorgbio.2020.110995  0.65
2020 Eirin MV, Sánchez-Temprano A, Learte-Aymamí S, Caeiro J, Pazos E, Mascareñas J, Vazquez M, Mayán M. The senolytic activity of connexin43 peptides target senescence in osteoarthritis: new treatment approaches based on targeted therapy Osteoarthritis and Cartilage. 28: S202-S203. DOI: 10.1016/J.Joca.2020.02.329  0.648
2019 Sánchez MI, Rama G, Calo-Lapido R, Ucar K, Lincoln P, López MV, Melle-Franco M, Mascareñas JL, Vázquez ME. Canonical DNA minor groove insertion of bisbenzamidine-Ru(ii) complexes with chiral selectivity. Chemical Science. 10: 8668-8674. PMID 31803441 DOI: 10.1039/C9Sc03053K  0.84
2019 Calo-Lapido R, Penas C, Jiménez-Balsa A, Vázquez ME, Mascareñas JL. A chemical approach for the synthesis of the DNA-binding domain of the oncoprotein MYC. Organic & Biomolecular Chemistry. PMID 31166361 DOI: 10.1039/c9ob01209e  0.754
2018 Gómez-González J, Peña DG, Barka G, Sciortino G, Maréchal JD, Vázquez López M, Vázquez ME. Directed Self-Assembly of Trimeric DNA-Bindingchiral Miniprotein Helicates. Frontiers in Chemistry. 6: 520. PMID 30425980 DOI: 10.3389/fchem.2018.00520  0.365
2018 Rodríguez J, Learte-Aymamí S, Mosquera J, Celaya G, Rodríguez-Larrea D, Vázquez ME, Mascareñas JL. DNA-binding miniproteins based on zinc fingers. Assessment of the interaction using nanopores. Chemical Science. 9: 4118-4123. PMID 29780541 DOI: 10.1039/C7Sc05441F  0.862
2018 Bouzada D, Salvadó I, Barka G, Rama G, Martínez-Costas J, Lorca R, Somoza Á, Melle-Franco M, Vázquez ME, Vázquez López M. Selective G-quadruplex binding by oligoarginine-Ru(dppz) metallopeptides. Chemical Communications (Cambridge, England). PMID 29300399 DOI: 10.1039/C7Cc08286J  0.808
2017 Learte-Aymamí S, Curado N, Rodríguez J, Vázquez ME, Mascareñas JL. Metal-dependent DNA recognition and cell internalization of designed, basic peptides. Journal of the American Chemical Society. PMID 29056048 DOI: 10.1021/Jacs.7B07422  0.837
2016 Rodriguez J, Mosquera J, Couceiro JR, Nitschke J, Vázquez ME, Mascareñas JL. Anion Recognition as a Supramolecular Switch of Cell Internalization. Journal of the American Chemical Society. PMID 27984855 DOI: 10.1021/Jacs.6B11103  0.79
2016 Rodríguez J, Mosquera J, Couceiro JR, Vázquez ME, Mascareñas JL. Ruthenation of Non-stacked Guanines in DNA G-Quadruplex Structures: Enhancement of c-MYC Expression. Angewandte Chemie (International Ed. in English). PMID 27860057 DOI: 10.1002/Anie.201607965  0.806
2016 Pazos E, Garcia Algar M, Penas C, Nazarenus M, Torruella A, Pazos-Perez N, Guerrini L, Vázquez ME, Garcia-Rico E, Mascareñas JL, Alvarez-Puebla RA. SERS Surface Selection Rules for the Proteomic Liquid Biopsy in Real Samples: Efficient Detection of the Oncoprotein c-MYC. Journal of the American Chemical Society. PMID 27731990 DOI: 10.1021/Jacs.6B08957  0.654
2016 Salvadó I, Gamba I, Montenegro J, Martínez-Costas J, Brea JM, Loza MI, Vázquez López M, Vázquez ME. Membrane-disrupting iridium(iii) oligocationic organometallopeptides. Chemical Communications (Cambridge, England). PMID 27538788 DOI: 10.1039/c6cc05537k  0.767
2016 Rodríguez J, Mosquera J, Vázquez ME, Mascareñas JL. Nickel-Promoted Recognition of Long DNA Sites by Designed Peptide Derivatives. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 27484723 DOI: 10.1002/Chem.201602783  0.838
2016 Penas C, Mascareñas JL, Vázquez ME. Coupling the folding of a β-hairpin with chelation-enhanced luminescence of Tb(III) and Eu(III) ions for specific sensing of a viral RNA. Chemical Science (Royal Society of Chemistry : 2010). 2016: 2674-2678. PMID 27293537 DOI: 10.1039/C5Sc04501K  0.671
2016 Rodríguez J, Mosquera J, García-Fandiño R, Vázquez ME, Mascareñas JL. A designed DNA binding motif that recognizes extended sites and spans two adjacent major grooves. Chemical Science (Royal Society of Chemistry : 2010). 7: 3298-3303. PMID 27252825 DOI: 10.1039/C6Sc00045B  0.86
2016 Pazos E, Mascareñas JL, Vázquez ME. Identification of Cyclin A Binders with a Fluorescent Peptide Sensor. Methods in Molecular Biology (Clifton, N.J.). 1336: 67-83. PMID 26231709 DOI: 10.1007/978-1-4939-2926-9_7  0.711
2015 Gamba I, Salvadó I, Brissos RF, Gamez P, Brea J, Loza MI, Vázquez ME, López MV. High-affinity sequence-selective DNA binding by iridium(iii) polypyridyl organometallopeptides. Chemical Communications (Cambridge, England). PMID 26611126 DOI: 10.1039/c5cc07619f  0.834
2015 Penas C, Sánchez MI, Guerra-Varela J, Sánchez L, Vazquez ME, Mascarenas JL. Light-controlled cellular internalization and cytotoxicity of nucleic acid-binding agents. Studies in vitro and in zebrafish embryos. Chembiochem : a European Journal of Chemical Biology. PMID 26534774 DOI: 10.1002/Cbic.201500455  0.825
2015 Rodríguez J, Mosquera J, Couceiro JR, Vázquez ME, Mascareñas JL. The AT-Hook motif as a versatile minor groove anchor for promoting DNA binding of transcription factor fragments. Chemical Science (Royal Society of Chemistry : 2010). 6: 4767-4771. PMID 26290687 DOI: 10.1039/C5Sc01415H  0.863
2015 Pazos E, Portela C, Penas C, Vázquez ME, Mascareñas JL. Peptide-DNA conjugates as tailored bivalent binders of the oncoprotein c-Jun. Organic & Biomolecular Chemistry. 13: 5385-90. PMID 25778494 DOI: 10.1039/C5Ob00318K  0.713
2015 Mosquera J, Sánchez MI, Valero J, de Mendoza J, Vázquez ME, Mascareñas JL. Sequence-selective DNA binding with cell-permeable oligoguanidinium-peptide conjugates. Chemical Communications (Cambridge, England). 51: 4811-4. PMID 25692277 DOI: 10.1039/C4Cc09525A  0.85
2015 Bordello J, Sánchez MI, Vázquez ME, Mascareñas JL, Al-Soufi W, Novo M. Fluorescence-labeled bis-benzamidines as fluorogenic DNA minor-groove binders: photophysics and binding dynamics. Chemistry (Weinheim An Der Bergstrasse, Germany). 21: 1609-19. PMID 25418429 DOI: 10.1002/Chem.201404926  0.838
2014 Sánchez MI, Penas C, Vázquez ME, Mascareñas JL. Metal-catalyzed uncaging of DNA-binding agents in living cells†Electronic supplementary information (ESI) available: Synthesis and characterization of the studied molecules and required precursors. NMR, UV, and fluorescence spectra, titrations, control experiments, and detailed procedures for cell uptake and co-staining experiments. See DOI: 10.1039/c3sc53317dClick here for additional data file. Chemical Science (Royal Society of Chemistry : 2010). 5: 1901-1907. PMID 25632343 DOI: 10.1039/C3Sc53317D  0.836
2014 Sánchez MI, Martínez-Costas J, Mascareñas JL, Vázquez ME. MitoBlue: a nontoxic and photostable blue-emitting dye that selectively labels functional mitochondria. Acs Chemical Biology. 9: 2742-7. PMID 25325672 DOI: 10.1021/Cb500552F  0.764
2014 Mosquera J, Sánchez MI, Vázquez ME, Mascareñas JL. Ruthenium bipyridyl complexes as photocleavable dimerizers: deactivation of DNA-binding peptides using visible light. Chemical Communications (Cambridge, England). 50: 10975-8. PMID 25093860 DOI: 10.1039/C4Cc04512B  0.83
2014 Sánchez MI, Mosquera J, Vázquez ME, Mascareñas JL. Reversible supramolecular assembly at specific DNA sites: nickel-promoted bivalent DNA binding with designed peptide and bipyridyl-bis(benzamidine) components. Angewandte Chemie (International Ed. in English). 53: 9917-21. PMID 25044619 DOI: 10.1002/Anie.201405726  0.844
2014 Gamba I, Rama G, Ortega-Carrasco E, Maréchal JD, Martínez-Costas J, Vázquez ME, Vázquez López M. Programmed stereoselective assembly of DNA-binding helical metallopeptides. Chemical Communications (Cambridge, England). 50: 11097-100. PMID 25014483 DOI: 10.1039/c4cc03606a  0.375
2014 Sánchez MI, Penas C, Vázquez ME, Mascareñas JL. Metal-catalyzed uncaging of DNA-binding agents in living cells. Chemical Science (Royal Society of Chemistry : 2010). 2014: 1901-1907. PMID 24955233  0.82
2014 Mosquera J, Rodríguez J, Vázquez ME, Mascareñas JL. Selective DNA-binding by designed bisbenzamidine-homeodomain chimeras. Chembiochem : a European Journal of Chemical Biology. 15: 1092-5. PMID 24764315 DOI: 10.1002/Cbic.201400079  0.754
2014 Rodríguez J, Mosquera J, Vázquez O, Vázquez ME, Mascareñas JL. The ββα fold of zinc finger proteins as a "natural" protecting group. Chemoselective synthesis of a DNA-binding zinc finger derivative. Chemical Communications (Cambridge, England). 50: 2258-60. PMID 24418796 DOI: 10.1039/C3Cc47599A  0.835
2013 Gamba I, Salvadó I, Rama G, Bertazzon M, Sánchez MI, Sánchez-Pedregal VM, Martínez-Costas J, Brissos RF, Gamez P, Mascareñas JL, Vázquez López M, Vázquez ME. Custom-fit ruthenium(II) metallopeptides: a new twist to DNA binding with coordination compounds. Chemistry (Weinheim An Der Bergstrasse, Germany). 19: 13369-75. PMID 23943195 DOI: 10.1002/Chem.201301629  0.855
2013 Sánchez MI, Vázquez O, Vázquez ME, Mascareñas JL. Sequence-selective DNA recognition with peptide-bisbenzamidine conjugates. Chemistry (Weinheim An Der Bergstrasse, Germany). 19: 9923-9. PMID 23780839 DOI: 10.1002/Chem.201300519  0.844
2013 Mosquera J, Jiménez-Balsa A, Dodero VI, Vázquez ME, Mascareñas JL. Stimuli-responsive selection of target DNA sequences by synthetic bZIP peptides. Nature Communications. 4: 1874. PMID 23695668 DOI: 10.1038/ncomms2825  0.689
2012 Jiménez-Balsa A, Pazos E, Martínez-Albardonedo B, Mascareñas JL, Vázquez ME. Temporary electrostatic impairment of DNA recognition: light-driven DNA binding of peptide dimers. Angewandte Chemie (International Ed. in English). 51: 8825-9. PMID 22851533 DOI: 10.1002/Anie.201201627  0.531
2012 Bordello J, Sánchez MI, Vázquez ME, Mascareñas JL, Al-Soufi W, Novo M. Single-molecule approach to DNA minor-groove association dynamics. Angewandte Chemie (International Ed. in English). 51: 7541-4. PMID 22700034 DOI: 10.1002/Anie.201201099  0.803
2012 Sánchez MI, Martínez-Costas J, Gonzalez F, Bermudez MA, Vázquez ME, Mascareñas JL. In vivo light-driven DNA binding and cellular uptake of nucleic acid stains. Acs Chemical Biology. 7: 1276-80. PMID 22550994 DOI: 10.1021/Cb300100R  0.807
2011 Sánchez MI, Vázquez O, Vázquez ME, Mascareñas JL. Light-controlled DNA binding of bisbenzamidines. Chemical Communications (Cambridge, England). 47: 11107-9. PMID 21909542 DOI: 10.1039/C1Cc13355A  0.813
2011 Pazos E, Mosquera J, Vázquez ME, Mascareñas JL. DNA recognition by synthetic constructs. Chembiochem : a European Journal of Chemical Biology. 12: 1958-73. PMID 21805550 DOI: 10.1002/Cbic.201100247  0.717
2010 Vázquez O, Sánchez MI, Mascareñas JL, Vázquez ME. dsDNA-triggered energy transfer and lanthanide sensitization processes. Luminescent probing of specific A/T sequences. Chemical Communications (Cambridge, England). 46: 5518-20. PMID 20458409 DOI: 10.1039/B927305K  0.754
2010 Vázquez O, Sánchez MI, Martínez-Costas J, Vázquez ME, Mascareñas JL. Bis-4-aminobenzamidines: versatile, fluorogenic A/T-selective dsDNA binders. Organic Letters. 12: 216-9. PMID 20000489 DOI: 10.1021/Ol902501J  0.791
2009 Pazos E, Vázquez O, Mascareñas JL, Vázquez ME. Peptide-based fluorescent biosensors. Chemical Society Reviews. 38: 3348-59. PMID 20449054 DOI: 10.1039/B908546G  0.786
2008 Vázquez O, Blanco-Canosa JB, Vázquez ME, Martínez-Costas J, Castedo L, Mascareñas JL. Efficient DNA binding and nuclear uptake by distamycin derivatives conjugated to octa-arginine sequences. Chembiochem : a European Journal of Chemical Biology. 9: 2822-9. PMID 18942688 DOI: 10.1002/Cbic.200800345  0.849
2008 Pazos E, Torrecilla D, Vázquez López M, Castedo L, Mascareñas JL, Vidal A, Vázquez ME. Cyclin A probes by means of intermolecular sensitization of terbium-chelating peptides. Journal of the American Chemical Society. 130: 9652-3. PMID 18593119 DOI: 10.1021/Ja803520Q  0.707
2007 Vázquez O, Vázquez ME, Blanco JB, Castedo L, Mascareñas JL. Specific DNA recognition by a synthetic, monomeric Cys2His2 zinc-finger peptide conjugated to a minor-groove binder. Angewandte Chemie (International Ed. in English). 46: 6886-90. PMID 17674388 DOI: 10.1002/Anie.200702345  0.839
2006 Blanco JB, Dodero VI, Vázquez ME, Mosquera M, Castedo L, Mascareñas JL. Sequence-specific DNA binding by noncovalent peptide-tripyrrole conjugates. Angewandte Chemie (International Ed. in English). 45: 8210-4. PMID 17111444 DOI: 10.1002/Anie.200603115  0.784
2005 Blanco JB, Vázquez ME, Castedo L, Mascareñas JL. Sequence-specific DNA recognition by monomeric bZIP basic regions equipped with a tripyrrole unit on the N-terminal side. Towards the development of synthetic mimics of Skn-1. Chembiochem : a European Journal of Chemical Biology. 6: 2173-6. PMID 16231291 DOI: 10.1002/Cbic.200500294  0.749
2005 Humphrey D, Rajfur Z, Vazquez ME, Scheswohl D, Schaller MD, Jacobson K, Imperiali B. In situ photoactivation of a caged phosphotyrosine peptide derived from focal adhesion kinase temporarily halts lamellar extension of single migrating tumor cells. The Journal of Biological Chemistry. 280: 22091-101. PMID 15817454 DOI: 10.1074/Jbc.M502726200  0.524
2005 Vázquez ME, Blanco JB, Imperiali B. Photophysics and biological applications of the environment-sensitive fluorophore 6-N,N-dimethylamino-2,3-naphthalimide. Journal of the American Chemical Society. 127: 1300-6. PMID 15669870 DOI: 10.1021/Ja0449168  0.559
2005 Rothman DM, Petersson EJ, Vázquez ME, Brandt GS, Dougherty DA, Imperiali B. Caged phosphoproteins. Journal of the American Chemical Society. 127: 846-7. PMID 15656617 DOI: 10.1021/ja043875c  0.624
2003 Vázquez ME, Caamaño AM, Mascareñas JL. From transcription factors to designed sequence-specific DNA-binding peptides. Chemical Society Reviews. 32: 338-49. PMID 14671789 DOI: 10.1039/B206274G  0.782
2003 Blanco JB, Vázquez ME, Martinez-Costas J, Castedo L, Mascareñas JL. A synthetic miniprotein that binds specific DNA sequences by contacting both the major and the minor groove. Chemistry & Biology. 10: 713-22. PMID 12954330 DOI: 10.1016/S1074-5521(03)00172-8  0.773
2003 Vázquez ME, Nitz M, Stehn J, Yaffe MB, Imperiali B. Fluorescent caged phosphoserine peptides as probes to investigate phosphorylation-dependent protein associations. Journal of the American Chemical Society. 125: 10150-1. PMID 12926919 DOI: 10.1021/Ja0351847  0.713
2003 Rothman DM, Vazquez ME, Vogel EM, Imperiali B. Caged phospho-amino acid building blocks for solid-phase peptide synthesis. The Journal of Organic Chemistry. 68: 6795-8. PMID 12919051 DOI: 10.1021/Jo0344891  0.655
2002 Rothman DM, Vázquez ME, Vogel EM, Imperiali B. General method for the synthesis of caged phosphopeptides: tools for the exploration of signal transduction pathways. Organic Letters. 4: 2865-8. PMID 12182575 DOI: 10.1021/Ol0262587  0.671
2001 Vázquez ME, Caamaño AM, Martínez-Costas J, Castedo L, Mascareñas JL. Design and Synthesis of a Peptide That Binds Specific DNA Sequences through Simultaneous Interaction in the Major and in the Minor Groove This work was supported by the Spanish M.E.C. (PB97-0524) and the Xunta de Galicia (PGIDT00PXI20912PR). M.E.V. and A.M.C. thank the Xunta de Galicia and the University of Santiago for their predoctoral fellowships. We are very grateful to Prof. G. L. Verdine for his input and support in the early phases of this work. We also thank Prof. J. Benavente for allowing us to use the radioactivity facilities and Prof. C. Abell for critical reading of the manuscript. Angewandte Chemie (International Ed. in English). 40: 4723-4725. PMID 12404395 DOI: 10.1002/1521-3773(20011217)40:24<4723::AID-ANIE4723>3.0.CO;2-L  0.678
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