| Year |
Citation |
Score |
| 2020 |
Yao B, Zhang S, Wei Y, Tian S, Lu Z, Jin L, He Y, Xie W, Li Y. Structural Insights into the Specificity of Ligand Binding and Coactivator Assembly by Estrogen-Related Receptor β. Journal of Molecular Biology. PMID 32795533 DOI: 10.1016/J.Jmb.2020.08.007 |
0.348 |
|
| 2015 |
Jin L, Wang R, Zhu Y, Zheng W, Han Y, Guo F, Ye FB, Li Y. Selective targeting of nuclear receptor FXR by avermectin analogues with therapeutic effects on nonalcoholic fatty liver disease. Scientific Reports. 5: 17288. PMID 26620317 DOI: 10.1038/Srep17288 |
0.33 |
|
| 2015 |
Zheng W, Qiu L, Wang R, Feng X, Han Y, Zhu Y, Chen D, Liu Y, Jin L, Li Y. Selective targeting of PPARγ by the natural product chelerythrine with a unique binding mode and improved antidiabetic potency. Scientific Reports. 5: 12222. PMID 26183621 DOI: 10.1038/Srep12222 |
0.304 |
|
| 2014 |
Yang C, Li Q, Li Y. Targeting Nuclear Receptors with Marine Natural Products Marine Drugs. 12: 601-635. PMID 24473166 DOI: 10.3390/Md12020601 |
0.333 |
|
| 2013 |
Jin L, Feng X, Rong H, Pan Z, Inaba Y, Qiu L, Zheng W, Lin S, Wang R, Wang Z, Wang S, Liu H, Li S, Xie W, Li Y. The antiparasitic drug ivermectin is a novel FXR ligand that regulates metabolism. Nature Communications. 4: 1937. PMID 23728580 DOI: 10.1038/Ncomms2924 |
0.349 |
|
| 2013 |
Zheng W, Feng X, Qiu L, Pan Z, Wang R, Lin S, Hou D, Jin L, Li Y. Identification of the antibiotic ionomycin as an unexpected peroxisome proliferator-activated receptor γ (PPARγ) ligand with a unique binding mode and effective glucose-lowering activity in a mouse model of diabetes Diabetologia. 56: 401-411. PMID 23178929 DOI: 10.1007/S00125-012-2777-9 |
0.336 |
|
| 2012 |
Laurenzana EM, Chen T, Kannuswamy M, Sell BE, Strom SC, Li Y, Omiecinski CJ. The orphan nuclear receptor DAX-1 functions as a potent corepressor of the constitutive androstane receptor (NR1I3). Molecular Pharmacology. 82: 918-28. PMID 22896671 DOI: 10.1124/Mol.112.080721 |
0.327 |
|
| 2010 |
Jin L, Li Y. Structural and functional insights into nuclear receptor signaling. Advanced Drug Delivery Reviews. 62: 1218-26. PMID 20723571 DOI: 10.1016/J.Addr.2010.08.007 |
0.348 |
|
| 2010 |
Jin L, Martynowski D, Zheng S, Wada T, Xie W, Li Y. Structural basis for hydroxycholesterols as natural ligands of orphan nuclear receptor RORgamma. Molecular Endocrinology (Baltimore, Md.). 24: 923-9. PMID 20203100 DOI: 10.1210/Me.2009-0507 |
0.364 |
|
| 2010 |
Schopfer FJ, Cole MP, Groeger AL, Chen CS, Khoo NK, Woodcock SR, Golin-Bisello F, Motanya UN, Li Y, Zhang J, Garcia-Barrio MT, Rudolph TK, Rudolph V, Bonacci G, Baker PR, et al. Covalent peroxisome proliferator-activated receptor gamma adduction by nitro-fatty acids: selective ligand activity and anti-diabetic signaling actions. The Journal of Biological Chemistry. 285: 12321-33. PMID 20097754 DOI: 10.1074/Jbc.M109.091512 |
0.347 |
|
| 2008 |
Xu HE, Li Y. Ligand-Dependent and -Independent Regulation of PPARγ and Orphan Nuclear Receptors Science Signaling. 1. PMID 19050303 DOI: 10.1126/Scisignal.148Pe52 |
0.344 |
|
| 2008 |
Li Y, Zhang J, Schopfer FJ, Martynowski D, Garcia-Barrio MT, Kovach A, Suino-Powell K, Baker PRS, Freeman BA, Chen YE, Xu HE. Molecular recognition of nitrated fatty acids by PPARγ Nature Structural and Molecular Biology. 15: 865-867. PMID 18604218 DOI: 10.1038/Nsmb.1447 |
0.318 |
|
| 2008 |
Li Y, Kovach A, Suino-Powell K, Martynowski D, Xu HE. Structural and biochemical basis for the binding selectivity of peroxisome proliferator-activated receptor gamma to PGC-1alpha. Journal of Biological Chemistry. 283: 19132-19139. PMID 18469005 DOI: 10.1074/Jbc.M802040200 |
0.306 |
|
| 2006 |
Motola DL, Cummins CL, Rottiers V, Sharma KK, Li T, Li Y, Suino-Powell K, Xu HE, Auchus RJ, Antebi A, Mangelsdorf DJ. Identification of ligands for DAF-12 that govern dauer formation and reproduction in C. elegans. Cell. 124: 1209-23. PMID 16529801 DOI: 10.1016/J.Cell.2006.01.037 |
0.328 |
|
| 2005 |
Li Y, Suino K, Daugherty J, Xu HE. Structural and biochemical mechanisms for the specificity of hormone binding and coactivator assembly by mineralocorticoid receptor Molecular Cell. 19: 367-380. PMID 16061183 DOI: 10.1016/J.Molcel.2005.06.026 |
0.325 |
|
| 2005 |
Li Y, Choi M, Suino K, Kovach A, Daugherty J, Kliewer SA, Xu HE. Structural and biochemical basis for selective repression of the orphan nuclear receptor liver receptor homolog 1 by small heterodimer partner. Proceedings of the National Academy of Sciences of the United States of America. 102: 9505-10. PMID 15976031 DOI: 10.1073/Pnas.0501204102 |
0.353 |
|
| 2005 |
Li Y, Choi M, Cavey G, Daugherty J, Suino K, Kovach A, Bingham NC, Kliewer SA, Xu HE. Crystallographic identification and functional characterization of phospholipids as ligands for the orphan nuclear receptor steroidogenic factor-1. Molecular Cell. 17: 491-502. PMID 15721253 DOI: 10.1016/J.Molcel.2005.02.002 |
0.354 |
|
| 2004 |
Suino K, Peng L, Reynolds R, Li Y, Cha JY, Repa JJ, Kliewer SA, Xu HE. The Nuclear Xenobiotic Receptor CAR: Structural Determinants of Constitutive Activation and Heterodimerization Molecular Cell. 16: 893-905. PMID 15610733 DOI: 10.1016/J.Molcel.2004.11.036 |
0.349 |
|
| 2003 |
Li Y, Lambert MH, Xu HE. Activation of nuclear receptors: A perspective from structural genomics Structure. 11: 741-746. PMID 12842037 DOI: 10.1016/S0969-2126(03)00133-3 |
0.349 |
|
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